bioRxiv preprint doi: https://doi.org/10.1101/2020.01.22.915728; this version posted April 15, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. Ketamine blocks morphine-induced conditioned place preference and anxiety-like behaviors in mice. Authors: Greer McKendrick1,3, Hannah Garrett3,6, Holly E. Jones2,3,6, Dillon S. McDevitt2,3, Sonakshi Sharma3, Yuval Silberman4, Nicholas M. Graziane5* Author Affiliations: 1 Neuroscience graduate program, Penn State College of Medicine, Hershey, PA 17033, USA 2 Summer Undergraduate Research Internship Program, Penn State College of Medicine 3Department of Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Hershey, PA 17033, USA 4Department of Neural and Behavioral Sciences, Penn State College of Medicine, Hershey, PA 17033, USA 5Departments of Anesthesiology and Perioperative Medicine and Pharmacology, Penn State College of Medicine, Hershey, PA 17033, USA 6These authors contributed equally: Hannah Garrett and Holly E. Jones. * Correspondence: Nicholas Graziane, Ph.D. E-mail:
[email protected] Address: Department of Anesthesiology and Perioperative Medicine, Mail Code H187 Pennsylvania State College of Medicine 500 University Drive Hershey, PA 17033 Telephone: 717-531-0003 X-329159 Fax: 717-531-6221 Running title: Ketamine effects on morphine-induced CPP bioRxiv preprint doi: https://doi.org/10.1101/2020.01.22.915728; this version posted April 15, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity.