Reports of Increases in Opioid-Related Overdose During COVID Pandemic
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The Effects of Recreational Marijuana Legislation on the Opioid Epidemic in Washington State" (2018)
Claremont Colleges Scholarship @ Claremont CMC Senior Theses CMC Student Scholarship 2018 The ffecE ts of Recreational Marijuana Legislation on the Opioid Epidemic in Washington State Steven Dickerson Claremont McKenna College Recommended Citation Dickerson, Steven, "The Effects of Recreational Marijuana Legislation on the Opioid Epidemic in Washington State" (2018). CMC Senior Theses. 1757. http://scholarship.claremont.edu/cmc_theses/1757 This Open Access Senior Thesis is brought to you by Scholarship@Claremont. It has been accepted for inclusion in this collection by an authorized administrator. For more information, please contact [email protected]. Claremont McKenna College The Effects of Recreational Marijuana Legislation on the Opioid Epidemic in Washington State Submitted to Professor David Bjerk By: Steven Reid Dickerson Jr. for Senior Thesis Fall 2017 December 4th Table of Contents Abstract 2 Acknowledgments 3 Introduction 4 Literature Summary 7 A History of the Opioid Epidemic 7 The History of Marijuana Legislation in the United States 10 The Effect of Marijuana Laws on Opioid Usage 12 Data 13 Opioid Overdose Crude Death Rate 14 Self-Reported Drug Usage 15 Treatment Admissions 15 Empirical Strategy 16 Analysis 19 Opioid Overdose Crude Death Rates 19 Self-Reported Opioid Usage 24 -
Substance Use Resources for Grades 7-12
1 Substance Use Resources for Grades 7-12 Online Resource Library Search: https://www.voa-dakotas.org/resource-library Addiction: page 1 Alcohol: page 1 Drugs: page 4 Vaping/tobacco: page 10 Addiction Addiction and the Human Brain o DVD, 2006, HRM, 27 minutes, Grades 7-12 o Drug addiction is a disease of the brain and teens are at highest risk for acquiring this disease. This DVD explains the changes to the brain caused by prolonged use of drugs and shows why voluntary drug use eventually becomes involuntary and compulsive. Studies indicate that drugs affect the developing brain more than the brain of someone more mature, thus putting teens at a higher risk of addiction. Interviews with recovering teen addicts, an addiction counselor, and brain experts and researchers provide sobering considerations to viewers. Pre- and Post-tests are included. How Addiction Hijacks the Brain o DVD, 2016, HRM, CC, 24 minutes, Grades 7-College o This film drives home the message that drug and alcohol addiction are a disease of the brain and that teens are at highest risk for acquiring this disease. Leading scientists detail how drugs like heroin, nicotine, cocaine and marijuana change the brain, subvert the way it registers pleasure, and corrupt learning and motivation. Young recovering addicts provide a human face to the effects of drugs and alcohol as they describe how addiction involves intense craving for a drug and loss of control over its use. Viewers also learn that the brain’s plasticity, or ability to change, offers hope for addicts that they can turn their lives around. -
Empirical Evidence for Definitions of Episode, Remission, Recovery, Relapse and Recurrence in Depression: a Systematic Review
Epidemiology and Psychiatric Sciences (2019), 28, 544–562. © Cambridge University Press 2018 ORIGINAL ARTICLE doi:10.1017/S2045796018000227 Empirical evidence for definitions of episode, remission, recovery, relapse and recurrence in depression: a systematic review P. L. de Zwart1*, B. F. Jeronimus1,2 and P. de Jonge1,2 1 University of Groningen, University Medical Center Groningen, Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), Groningen, The Netherlands 2 University of Groningen, Faculty of Behavioural and Social Sciences, Department of Developmental Psychology, Groningen, The Netherlands Aims. For the past quarter of a century, Frank et al.’s (1991) consensus-based definitions of major depressive disorder (MDD) episode, remission, recovery, relapse and recurrence have been the paramount driving forces for consistency in MDD research as well as in clinical practice. This study aims to review the evidence for the empirical validation of Frank et al.’s proposed concept definitions and to discuss evidence-based modifications. Methods. A literature search of Web of Science and PubMed from 1/1/1991 to 08/30/2017 identified all publications which referenced Frank et al.’s request for definition validation. Publications with data relevant for validation were included and checked for referencing other studies providing such data. Results. A total of 56 studies involving 39 315 subjects were included, mainly presenting data to validate the severity and duration thresholds for defining remission and recovery. Most studies indicated that the severity threshold for defining remission should decrease. Additionally, specific duration thresholds to separate remission from recovery did not add any predictive value to the notion that increased remission duration alleviates the risk of reoccurrence of depressive symp- toms. -
Impact of Disclosure of Relapse for Self-Identified Sexual Addicts
Sexual Addiction & Compulsivity, 20:157–170, 2013 Copyright © Taylor & Francis Group, LLC ISSN: 1072-0162 print / 1532-5318 online DOI: 10.1080/10720162.2013.786659 ARTICLES Impact of Disclosure of Relapse for Self-Identified Sexual Addicts M. DEBORAH CORLEY Sante´ Center for Healing, Argyle, Texas SARA E. POLLARD and JOSHUA N. HOOK University of North Texas, Denton, Texas JENNIFER P. SCHNEIDER Tucson, Arizona Disclosure as a process of both recovery and healing within commit- ted relationships is advocated by couple and addiction therapists. The traumatic impact for partners of an initial disclosure or discov- ery of betrayals has been well documented, but less is known about the impact of disclosure for sex addicts. The present study explored the experience of relapse and disclosure among sex addicts. Relapse was a common experience among sex addicts, and the disclosure of relapse had a range of consequences for the addict and the re- lationship. Voluntary disclosure of relapse (rather than the partner discovering relapses independently) was associated with positive relational outcomes. The majority of sexual behaviors engaged in by sexual addicts who are in a committed relationship are considered a violation of trust by their partners (Bird, Butler, & Fife, 2007; Kalichman & Cain, 2004; Young, Griffin-Shelley, Cooper, O’Mara, & Buchanan, 2000). This violation is also considered a betrayal and may be described as a secret sexual, romantic, or emotional involvement that violates the rules of and commitment to an exclusive re- lationship (Glass, 2002; Laaser, 2011; Whisman & Wagers, 2005). The most significant betrayals are those associated with repeated secrets, lies, decep- tions, and broken promises (Corley & Schneider, 2002; Corley, Schneider, Thanks to Dr. -
Medications to Treat Opioid Use Disorder Research Report
Research Report Revised Junio 2018 Medications to Treat Opioid Use Disorder Research Report Table of Contents Medications to Treat Opioid Use Disorder Research Report Overview How do medications to treat opioid use disorder work? How effective are medications to treat opioid use disorder? What are misconceptions about maintenance treatment? What is the treatment need versus the diversion risk for opioid use disorder treatment? What is the impact of medication for opioid use disorder treatment on HIV/HCV outcomes? How is opioid use disorder treated in the criminal justice system? Is medication to treat opioid use disorder available in the military? What treatment is available for pregnant mothers and their babies? How much does opioid treatment cost? Is naloxone accessible? References Page 1 Medications to Treat Opioid Use Disorder Research Report Discusses effective medications used to treat opioid use disorders: methadone, buprenorphine, and naltrexone. Overview An estimated 1.4 million people in the United States had a substance use disorder related to prescription opioids in 2019.1 However, only a fraction of people with prescription opioid use disorders receive tailored treatment (22 percent in 2019).1 Overdose deaths involving prescription opioids more than quadrupled from 1999 through 2016 followed by significant declines reported in both 2018 and 2019.2,3 Besides overdose, consequences of the opioid crisis include a rising incidence of infants born dependent on opioids because their mothers used these substances during pregnancy4,5 and increased spread of infectious diseases, including HIV and hepatitis C (HCV), as was seen in 2015 in southern Indiana.6 Effective prevention and treatment strategies exist for opioid misuse and use disorder but are highly underutilized across the United States. -
The Opioid Epidemic: What Labs Have to Do with It?
The Opioid Epidemic: What labs have to do with it? Ewa King, Ph.D. Associate Director of Health RIDOH State Health Laboratories Analysis. Answers. Action. www.aphl.org Overview • Overdose trends • Opioids and their effects • Analytical testing approaches • Toxicology laboratories Analysis. Answers. Action. www.aphl.org Opioid overdose crisis 1 Analysis. Answers. Action. www.aphl.org Opioid overdose crisis 2 Analysis. Answers. Action. www.aphl.org Opiates and Opioids • Opiates vs. Opioids • Opiates: Naturally occurring, derived from the poppy plant • Opioids: “Opiate-like” drugs in effects, not chemical structure Includes opiates • Narcotic analgesics • CNS depressants • DEA Schedule I or II controlled substances • Additive effect with other CNS depressant drugs Analysis. Answers. Action. www.aphl.org Efficacy of Opioids • How do opioids work? • Bind with opioid receptors • Brain, spinal cord, GI tract, and throughout the body • Pain, emotion, breathing, movement, and digestion Opioid Receptor Analysis. Answers. Action. www.aphl.org Effects of Opioids Physiological Psychological • Pain relief • Drowsiness/ sedation • Cough suppression • Mental confusion • GI motility • Loss of memory • Respiratory depression • Lethargy/ apathy • Pupillary constriction • Euphoria/ tranquility • Itching • Mood swings • Constipation • Depression • Dependence • Withdrawal • Dependence Analysis. Answers. Action. www.aphl.org Opiates 1 Opiates • Naturally occurring alkaloids Opium • Latex from the opium poppy plant Codeine: • Mild to moderate pain • Antitussive Morphine: • Severe pain • Metabolite of codeine and heroin Analysis. Answers. Action. www.aphl.org Opiates 2 Semi-synthetic Opiates: • Synthesized from a natural opiate Heroin: • Schedule I narcotic Hydrocodone (Vicodin): • Mild to moderate pain • Metabolizes to hydromorphone (Dilaudid) Oxycodone (Oxycontin/Percocet): • Moderate to severe pain • Metabolizes to oxymorphone (Opana) Analysis. Answers. Action. -
Alcohol Use Disorder Relapse Factors a Systematic Review
Psychiatry Research 278 (2019) 97–115 Contents lists available at ScienceDirect Psychiatry Research journal homepage: www.elsevier.com/locate/psychres Alcohol use disorder relapse factors: A systematic review T ⁎ Wilco Sliedrechta, , Ranne de Waartb, Katie Witkiewitzc, Hendrik G. Roozend a De Hoop GGZ, Provincialeweg 70, 3329 KP Dordrecht, the Netherlands b Mentrum/Arkin, Wisselwerking 46-48, 1112 XR Diemen, the Netherlands c The University of New Mexico (UNM), MSC 03-2220, Univ of New Mexico, Albuquerque, NM 87131, USA d The University of New Mexico (UNM), Center on Alcoholism, Substance Abuse, and Addictions (CASAA), MSC 11 6280, 1 Univ of New Mexico, Albuquerque, NM 87106, USA ARTICLE INFO ABSTRACT Keywords: A relapsing-remitting course is very common in patients with an Alcohol Use Disorder (AUD). Understanding the Remittance determinants associated with alcohol resumption remains a formidable task. This paper examines relapse de- Recurrence terminants based on a systematic review of recent alcohol literature (2000–2019). Relevant databases were Relapse determinants consulted for articles that contained information about specific relapse determinants and reported statistical Dual diagnosis significance of each relapse determinant in predicting relapse. Relapse was broadly defined based on the Biopsychosocial model characterization in the included articles. From the initial identified 4613 papers, a total of 321 articles were Spiritual included. Results encompass multiple relapse determinants, which were ordered according to biopsychosocial and spiritual categories, and presented, using a descriptive methodology. Psychiatric co-morbidity, AUD se- verity, craving, use of other substances, health and social factors were consistently significantly associated with AUD relapse. Conversely, supportive social network factors, self efficacy, and factors related to purpose and meaning in life, were protective against AUD relapse. -
National Vital Statistics Report: Drugs Most Frequently Involved In
National Vital Statistics Reports Volume 67, Number 9 December 12, 2018 Drugs Most Frequently Involved in Drug Overdose Deaths: United States, 2011–2016 by Holly Hedegaard, M.D., M.S.P.H., and Brigham A. Bastian, B.S., National Center for Health Statistics; James P. Trinidad, M.P.H., M.S., U.S. Food and Drug Administration; Merianne Spencer, M.P.H., and Margaret Warner, Ph.D., National Center for Health Statistics Abstract overdose deaths involving methadone decreased from 1.4 per 100,000 in 2011 to 1.1 in 2016. The 10 most frequently Objective—This report identifies the specific drugs involved mentioned drugs often were found in combination with each most frequently in drug overdose deaths in the United States other. The drugs most frequently mentioned varied by the intent from 2011 through 2016. of the drug overdose death. In 2016, the drugs most frequently Methods—Record-level data from the 2011–2016 National mentioned in unintentional drug overdose deaths were fentanyl, Vital Statistics System–Mortality files were linked to electronic heroin, and cocaine, while the drugs most frequently mentioned files containing literal text information from death certificates. in suicides by drug overdose were oxycodone, diphenhydramine, Drug overdose deaths were identified using the International hydrocodone, and alprazolam. Classification of Diseases, Tenth Revision underlying cause- Conclusions—This report identifies patterns in the specific of-death codes X40–X44, X60–X64, X85, and Y10–Y14. Drug drugs most frequently involved in drug overdose deaths from mentions were identified by searching the literal text in three 2011 through 2016 and highlights the importance of complete fields of the death certificate: the causes of death from Part I, and accurate reporting in the literal text on death certificates. -
Washington DC's Opioid Strategic Plan
Updated as of March 2019 Letter from Mayor Muriel Bowser Too many of our neighbors in Washington, DC lose their lives or family members and friends to a substance use disorder. Many of these cases involve opioid overdoses. The District’s multi-stakeholder, public health approach has yielded progress in saving lives and reducing fatal overdoses, but there is still work to be done to reduce the impact of the epidemic on our city. “LIVE.LONG.DC,” Washington, DC’s Strategic Plan to Reduce Opioid Use, Misuse and Related Deaths is our blueprint for how best to continue moving forward with urgency and thoughtfulness as we work towards reversing fatal opioid overdoses. The Plan reflects the input of a cross-section of public and private partners, including DC government agencies, hospital leaders, physicians, substance use disorder treatment providers, community-based service providers, federal partners, and individuals in recovery. The updated Plan offers a comprehensive look at prevention, treatment, and recovery, detailing our goals and accompanying strategies to end Washington, DC’s opioid epidemic. Our Plan offers additional details on how these goals and strategies will be accomplished in order to ensure District residents can thrive and move forward with the support they need. Working together, the implementation of LIVE.LONG.DC has resulted in some early successes, which include: Reversing more than 1,000 overdoses through naloxone kits and training residents in naloxone use; Increasing the capacity of practitioners to provide Buprenorphine-based medication-assisted treatment (MAT); Monitoring trends in opioid use and tailoring responses and interventions based on real-time data; Increasing testing capacity via surveillance of synthetic opioids in the District, both to discover new synthetic opioids as well as characterize those currently present; and Revising innovative public education campaigns targeting those who are most likely to overdose on heroin and to educate young people on the dangers of misusing prescription opioids. -
Epidemic of Prescription Drug Overdose in Ohio
EPIDEMIC OF PRESCRIPTION There were more deaths in 2008 and 2009 in Ohio from D RUG OVERDOSE IN OHIO unintentional drug overdose than from DID YOU KNOW? motor vehicle In 2007, unintentional drug poisoning became the leading crashes! cause of injury death in Ohio, surpassing motor vehicle crashes and suicide for the first time on record. This trend continued in 2009. (See Figure 1) Among the leading causes of injury death (see below), unintentional poisonings increased from the cause of the fewest number of annual deaths in 1999 (369 deaths) to the greatest in 2009 (1,817).i (See Figure 2) From 1999 to 2009, Ohio’s death rate due to unintentional drug poisonings increased 335 percent, and the increase in deaths has been driven largely by prescription drug overdoses. In Ohio, there were 327 fatal unintentional drug overdoses in 1999 growing to 1,423 annual deaths in 2009. On average, from 2006 to 2009, approximately four people died each day in Ohio due to drug overdose.v Figure 1. Number of deaths from MV traffic Figure 2 . Percent change in the number of deaths for and unintentional drug poisonings by year, the leading causes of injury, Ohio 1999-20091,2 Ohio, 2000-20091,2 1800 all unintentional 39% 1600 firearm related 15% 1400 1200 homicide 34% 1000 unintentional suicide 17% 800 poisoning 600 unintentional poisoning 301% unt MV traffic Number of deathsNumber 400 unt MV traffic -31% 200 unintentional falls 100% 0 -100% 0% 100% 200% 300% 400% Percent change from 2000-2009 Year 1Source: Ohio Department of Health, Office of Vital Statistics; 2 Unintentional Poisoning includes non-drug and drug-related poisoning. -
Safety Notice 009/20 Acetylfentanyl and Fentanyl In
Safety Notice 009/20 Acetylfentanyl and fentanyl in non-opioid illicit drugs 16 October 2020 Background Distributed to: A cluster of hospitalisations due to unexpected opioid toxicity recently occured on • Chief Executives the Central Coast of NSW. Acetylfentanyl and fentanyl are circulating in NSW and • Directors of Clinical Governance may be misrepresented as or be adulterants in illicit cocaine or ketamine. • Director Regulation and Acetylfentanyl has a similar potency to fentanyl, both may cause serious harm and Compliance Unit death. People who do not use opioids regularly (‘opioid naïve’) may be unintentionally exposed and are at high risk of overdose. Even people who Action required by: regularly use opioids are at risk due to the relatively high potency of fentanyl and • Chief Executives acetylfentanyl. • Directors of Clinical Changes in illicit drug use in 2020, as well as variations in purity and alternative Governance ingredients, may be associated with unusual presentations and overdose. • Director Regulation and Compliance Unit Case management • We recommend you also Have a high index of suspicion for illicit fentanyl and fentanyl analogues in inform: suspected opioid overdose. This includes people who deny opioid use or • Drug and Alcohol Directors report use of other non-opioid illicit drugs including ketamine or stimulants and staff such as cocaine, but who present clinically with signs of an opioid • All Service Directors overdose. • Emergency Department • Intensive Care Unit • Airway management, oxygenation, and ventilation support take precedence • Toxicology Units over naloxone, where appropriate. • Ambulance • Cases may require titrated doses of naloxone with a higher total dose of • All Toxicology Staff 800 micrograms or more. -
What Are the Treatments for Heroin Addiction?
How is heroin linked to prescription drug abuse? See page 3. from the director: Research Report Series Heroin is a highly addictive opioid drug, and its use has repercussions that extend far beyond the individual user. The medical and social consequences of drug use—such as hepatitis, HIV/AIDS, fetal effects, crime, violence, and disruptions in family, workplace, and educational environments—have a devastating impact on society and cost billions of dollars each year. Although heroin use in the general population is rather low, the numbers of people starting to use heroin have been steadily rising since 2007.1 This may be due in part to a shift from abuse of prescription pain relievers to heroin as a readily available, cheaper alternative2-5 and the misperception that highly pure heroin is safer than less pure forms because it does not need to be injected. Like many other chronic diseases, addiction can be treated. Medications HEROIN are available to treat heroin addiction while reducing drug cravings and withdrawal symptoms, improving the odds of achieving abstinence. There are now a variety of medications that can be tailored to a person’s recovery needs while taking into account co-occurring What is heroin and health conditions. Medication combined with behavioral therapy is particularly how is it used? effective, offering hope to individuals who suffer from addiction and for those around them. eroin is an illegal, highly addictive drug processed from morphine, a naturally occurring substance extracted from the seed pod of certain varieties The National Institute on Drug Abuse (NIDA) has developed this publication to Hof poppy plants.