For the Dietary Management of disorders in leucine metabolism in CHILDREN OVER 1 YEAR OF AGE, ADOLESCENTS AND ADULTS

• Concentrated mixture of pure L-amino acids DESCRIPTION • Free from leucine comida-Leu B is a concentrated amino acid mixture free from • Supplemented with vitamins, minerals and trace elements leucine for the dietary management of disorders in leucine • Free from sucrose metabolism, such as isovaleric acidemia. • Easy to prepare comida-Leu B is supplemented with vitamins, minerals and trace elements. INDICATIONS For the dietary treatment in children over 1 year of age, adolescents and adults with hyperleucinemia. RECOMMENDED USE The daily amount of comida-Leu B needed depends on age, body weight and individual metabolic condition. The dose of comida-Leu B is to be monitored and must be adjusted by the physician regularly. The daily amount required should be divided into 3 to 5 single portions and should be taken mixed also with food or beverages allowed in calculated amounts.

IMPORTANT NOTICE: • Not suitable as sole source of nutrition • Must be used under medical supervision • Not to be used by individuals without disorders in leucine metabolism • For children over 1 year of age, adolescents and adults with disorders in leucine metabolism • Not suitable for parenteral use

comida-Leu B is free from any preserving agent, colourings or sweeteners

produced in Food for Special GERMANY Medical Purposes Ingredients: L-Lysine-L-Aspartate, L-Glutamine, L-Proline, Potassium-L-Glutamate, L-Arginine-L-Aspartate, L-Serine, L-Valine, L-Isoleucine, L-Threonine, L-Lysine-L-Glutamate, tri-Calcium phosphate, L-Phenylalanine, L-Alanine, L-Tyrosine, Glycine, L-Cystine, L-Histidine, Maltodextrin, di-Calcium phosphate, Choline bitartrate, L-Tryptophan, L-Methionine, Sodium chloride, Magnesium carbonate, Vitamins (A, D, E, K, C, B1, B2, Niacin, B6, Folic acid, Pantothenic acid, B12, Biotin), Inositol, L-Carnitine-L-Tartrate, Taurine, tri-Potassium citrate, Vanillin, Iron-II-sulfate, Zinc sulfate, Potassium chloride, Manganese sulfate, Copper sulfate, Sodium fluoride, Sodium molybdate, Potassium iodide, Chromium-III-chloride, Sodium selenite.

Nutrition facts per 100 g Minerals per 100 g Energy kJ / kcal 1204 / 283 Sodium mg 614 Potassium mg 1386 Fat (of which) g < 0,5 Chloride mg 960 saturated fatty acids g < 0,1 Calcium mg 2278 Carbohydrates g 2,3 Phosphorus mg 1345 Magnesium mg 333 of which Sugar g < 0,5 Iron mg 31 Maltodextrin g 2,1 Trace elements Protein equivalent * g 69 Zinc mg 21 Copper µg 2401 Salt g 1,5 Iodine µg 343 Amino acids g 82 Chromium µg 69 Fluoride µg 412 L-Alanine g 3,9 Manganese µg 4802 L-Arginine g 3,4 Molybdenum µg 185 L-Aspartic acid g 7,1 Selenium µg 82 Vitamins L-Cystine g 2,3 Vitamin A µg 1378 L-Glutamic acid g 6,9 Vitamin D µg 21 L-Glutamine g 9,1 Vitamin E mg 24 Vitamin K µg 76 Glycine g 2,8 Vitamin C mg 185 L-Histidine g 2,3 Vitamin B1 µg 2265 L-Isoleucine g 4,7 Vitamin B2 µg 3089 Niacin mg 31 L-Lysin g 6,9 Vitamin B6 µg 2059 L-Methionine g 1,6 Folate (DFE) µg 572 L-Phenylalanine g 4,0 Pantothenic acid mg 18 Vitamin B12 µg 4,1 L-Proline g 7,2 Biotin µg 69 L-Serine g 5,2 L-Carnitine mg 172 Choline mg 892 L-Threonine g 4,6 Inositol mg 309 L-Tryptophan g 1,8 Taurine mg 172 L-Tyrosine g 3,7 L-Valine g 5,0 * Conversion: 1 g Protein = 1,2 g Amino acids = 17 kJ = 4 kcal