CancerResearch OFFICIAL JOURNAL OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH
January 1,1993 Volume 53 •¿ Number 1 PR1-207 ISSN0008-5472 •¿ CNREA 8 THE NATIONAL CHIEF NEUROFIBROMATOSISFOUNDATION HEMATOLOGY-ONCOLOGY DIVISION
announces the availability of A position is now available as Chief, Hematology- YOUNG INVESTIGATOR AWARDS Oncology Section, San Francisco VA Medical Center, with appointment at the Associate Professor or Profes which will provide salary support not to exceed sor of Medicine level at the University of California, $35,000 annually for period up to two years San Francisco. This is a leadership opportunity for an and oncologist or hematologist with a national reputation RESEARCH GRANTS as a biomedicai investigator, credentials to lead a strong clinical program, and an interest in training. The which will provide up to $50,000 for up to two years San Francisco VA is a UCSF teaching hospital, and for research on the cause and treatment of opportunities exist for participation in graduate pro neurofibromatosis 1 and 2 grams in the basic sciences at UCSF. Send curriculum vitaeto: The deadline for filing applications for funding beginning July 1, 1993, is Aprili, 1993. Gordon J. Strewler, M.D. Chair, SearchCommittee For information on applications please contact: DVA MedicalCenter(11IN) The National Neurofibromatosis Foundation 4150 ClementStreet 141 Fifth Avenue, Suite 7-S San Francisco,CA 94121 New York, NY 10010 (212) 460-8980 The University of California and the VA are Equal 1-800-323-7938 Opportunity/Affirmative Action Employers. Women Fax # (212) 529-6094 and minorities are encouraged to apply.
MEDICAL ONCOLOGISTS Assistant/Associate Professor Roswell Park Cancer Institute
Applications are being accepted for the positions of Assistant/Associate Professor of Medicine in Roswell ParkCancerlnstitute's Divisions of HématologieOncology and Bone Marrow Transplantation. The incumbent's responsibilities include providing consultative and attending services in HématologieOncology and/or Bone Marrow Transplantation, teaching students and supervising residents and fellows. Assistant Professor candidates must show evidence of experience in clinical care and teaching, and demonstrate potential to develop an outstanding clinical or laboratory research program in Oncology. Associate Professor candidates must provide evidence of development of a strong research program as well as demonstrate skill in clinical care and teaching. Candidates must be Board Certified in Internal Medicine and Board Eligible or Certified in Medical Oncology, as well as be able to meet Medical Licensure requirements in New York State. Send Curriculum Vitae to:
Clara D. Bloomfield, M.D. Head, Department of Medicine or Geoffrey P. Herzig, M.D. Chief, HématologieOncology and Bone Marrow Transplantation
Department of Medicine Roswell Park Cancer Institute Elm and Carlton Streets Buffalo, NY 14263
Roswell Park is a M/F/H/V Affirmative Action Employer AACR SPECIAL CONFERENCE IN CANCER RESEARCH OncogenesandAntioncogenesin Differentiation, Development,andHumanCancer
February1-6,1993 Big Sky Resort,Big Sky, Montana
CONFERENCE CHAIRPERSON
Carlo M. Croce / Philadelphia,PA
PROGRAM COMMITTEE
Stuart A. Aaronson / Bethesda, MD Mario R. Capecchi / Salt Lake City, UT Douglas Hanahan / San Francisco,CA
SCIENTIFIC PROGRAM
Keynote Address Tumor Suppressor Genes Eric J. Stanbridge' Irvine,CA RaymondL. White/ SaltLakeCity,UT Wen-HuaLee / SanAntonio,TX Gene Knockouts by Homologous DavidE. Housman/ Cambridge.MA Lennart Philipson Heidelberg.Germany Recombination I KarenVousdenI London.England Mario R. Capecchi SaltLakeCity.UT Allan Bradley Houston.TX Tyler Jacks Cambridge.MA Expression of Activated Oncogenes in BruceM. Speigelman Boston.MA Transgenic Mice I Allan Balmain' Glasgow.Scotland GeneKnockoutsby Homologous RobertS. Coffey/ Nashville,TN RecombinationII GilbertJay / Rockville.MD GeorgeF. VandeWoude Frederick.MD ErwinWagner Vienna.Austria HaroldE. Varmus SanFrancisco.CA DouglasHanahan' SanFrancisco.CA Expression of Activated Oncogenes in Transgenic Mice II Signal Transduction and Cancer I Terry Van Dyke Pittsburgh,PA StuartA. Aaronson/ Bethesda.MD AntonBerns/ Amsterdam.The Netherlands LewisC. Cantley Boston,MA AdditionalSpeakerto be Announced John J. Cohen Denver.CO DavidV. Goeddel S. SanFrancisco.CA
Signal Transduction and Cancer II MichaelH. Wigler ColdSpringHarbor.NY EdwardB. Ziff NewYork,NY MichaelJ. Weber' Richmond,VA InformationandApplicationForms
American Association for Cancer Research Chromosomal Translocations and Cancer Carlo M. Croce Philadelphia.PA Public Ledger Building MichaelL Cleary Stanford.CA 620 Chestnut Street, Suite 816 Eli Canaani Philadelphia.PA Philadelphia, PA 19106-3483 Anne Dejean Paris.France 215-440-9300 215-440-9313 (FAX) 83rd ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH MAY 20-23,1992 •¿ SAN DIEGO Each cassette is $11.50. •¿ Programs consists of one to three cassettes.
D CAN 201 Sixteenth Richard and Hinda Rosenthal D CAN 227 Symposium 5: Genomic Fluidity $11.50 Foundation Award Lecture: How Cancer« $23.00 (Two cassettes) Evade Chemotherapy D CAN 228 Symposium 6: Programmed Cell Death [Michael M. Gottesman] and General Motors $23.00 (Apoptosis) in the Etiology and Therapy of Cancer Research Foundation Journalism Cancer (Two cassettes) Awards (One cassette) D CAN 229 Symposium 7: Receptor Signaling and D CAN 202 JOINT AACR/ASCO PLENARY SESSION: $23.00 Transduction (Twocassettes) $23.00 Chemoprevention of Cancer D CAN 230 Minisymposium Epidemiology and (Two cassettes) $23.00 Prevention 2: Epidemiology and Prevention D CAN 203 Minisymposium Immunology 1: Vaccine (Twocassettes) $23.00 and Related Therapies (Two cassettes) D CAN 231 Minisymposium Clinical Investigations 10: D CAN 204 Minisymposium Preclinical $23.00 Novel Therapies (Two cassettes) $23.00 Pharmacology/Experimental D CAN 232 Minisymposium Carcinogenesis 11 : Therapeutics 1: New Methods for $23.00 Cellular and Molecular Changes in Predicting Drug Efficacy (Twocassettes) Carcinogenesis (Twocassettes) D CAN 205 Minisymposium Carcinogenesis 1: D CAN 233 Minisymposium Preclinical $23.00 Perturbations of Cell Cycle Control and $23.00 Pharmacology/Experimental Therapeutics Apoptosis (Two cassettes) 16: New Mechanisms of Multidrug Resistance D CAN 206 Minisymposium Biochemistry 1: Cellular (Two cassettes) $23.00 Responses to Genomic Insult D CAN 234 Presidential Address: Transforming Growth (Two cassettes) $11.50 Factors and Cancer: New Insights D CAN 207 Presentation by the Director of The [Harold L. Moses] (One cassette) $11.50 National Cancer Institute (One cassette) D CAN 235 Annual Business Meeting D CAN 208 Plenary Session 2: Novel Approaches to $11.50 (Onecassette) $23.00 Tumor Immunology (Twocassettes) D CAN 236 Meet the Expert Sunrise Session: D CAN 209 Symposium 1: Hereditary Predisposition $11.50 Proteoglycans and Cell Adhesion (One cassette) $23.00 to Cancer (Twocassettes) D CAN 237 Meet the Expert Sunrise Session: A New D CAN 210 Symposium 2: Antitumor Activities of $11.50 Therapeutic Approach for Cancer Treatment: $23.00 Cytokines (Two cassettes) Sequence-specific Antisense Nucleic Acid D CAN 211 Minisymposium Biology 3: Analogs (One cassette) $34.00 Metalloproteinases (Threecassettes) D CAN 238 Plenary Session 4: Cell Cycle Control D CAN 212 Minisymposium Preclinical $23.00 (Twocassettes) $34.00 Pharmacology/Experimental Therapeutics 4: D CAN 239 Symposium 8: HIV-associated Malignancies Protein Kinases: A Target for Therapy $23.00 (Two cassettes) (Threecassettes) D CAN 240 Symposium 9: Anticancer Drug Design and D CAN 213 Minisymposium Clinical Investigations 3: $23.00 Discovery (Two cassettes) $34.00 Molecular Markers of Risk and Prognosis D CAN 241 Minisymposium Endocrinology 5: (Threecassettes) $23.00 Endocrine, Autocrine, and Paracrine D CAN 214 Minisymposium Molecular Biology/ Growth Factors (Two cassettes) $34.00 Virology 3: Oncogenes (Threecassettes) D CAN 242 Minisymposium Biochemistry 5: Oncogenes D CAN 215 Eleventh Bruce F. Cain Memorial Award $23.00 (Twocassettes) $11.50 Lecture: Taxol: Mechanisms of Action and D CAN 243 Minisymposium Carcinogenesis 15: Genetics Resistance [Susan Band Horwitz] $23.00 of Cancer Susceptibility (Twocassettes) (One cassette) D CAN 244 Minisymposium Preclinical Pharmacology / D CAN 216 Minority Issues Committee Symposium: $23.00 Experimental Therapeutics 22: Antineoplastic $23.00 Careers and OpportunitésIn Cancer Properties of Ether Upids (Two cassettes) Research: Success and Survival in the D CAN 245 First American Cancer Society Award 1990« (Two cassettes) $11.50 Lecture: Human Gastric Carcinogenesis: A D CAN 217 Meet the Expert Sunrise Session: Multistep and Multifactorial Process $11.50 Contemporary Cytogenetics (One cassette) [Pelayo Correa] (One cassette) D CAN 218 Meet the Expert Sunrise Session: Gene D CAN 246 Eleventh Cornelius P. Rhoads Memorial $11.50 Therapy (One cassette) $11.50 Award Lecture: Analysis of Protein D CAN 219 Symposium 3: Molecular Genetics of Cancer Function in Vivo by Targeted Gene $34.50 (Three cassettes) Disruption [Elizabeth J. Robertson] D CAN 220 Plenary Session 3: The Role of Cell (One cassette) $23.00 Adhesion in Invasion and Metastasis D CAN 248 Symposium 10: The p53 Tumor Suppressor [Two cassettes) $23.00 Gene (Two cassettes) D CAN 221 Symposium 4: Multiple Genetic Alterations D CAN 249 Symposium 11 : Breast Cancer $23.00 and Multiple Steps In Carcinogenesis $23.00 (two cassettes) (Twocassettes) D CAN 250 Symposium 12: Gene Expression and D CAN 222 Minisymposium Immunology 4: Tumor $34.50 Chromatin Structure (Three cassettes) $34.50 Infiltrating Lymphocytes (Three cassettes) D CAN 251 Minisymposium Biology 15: Angiogenesis D CAN 223 Minisymposium Carcinogenesis 7: $34.50 (Three cassettes) $34.50 Molecular Alterations in Oncogenes and D CAN 252 Minisymposium Preclinical Tumor Suppressor Genes (Threecassettes) $34.50 Pharmacology/Experimental Therapeutics D CAN 224 Minisymposium Preclinical Pharmacology/ _ 33: Antisense (Three cassettes) $34.50 Experimental Therapeutics 10: Reversal of D CAN 253 Minisymposium Molecular Biology/Virology Drug Resistance III (Threecassettes) $23.00 11 : Tumor Suppressor Genes I D CAN 225 Minisymposium Clinical Investigations 7: (Two cassettes) $34.50 Biologicals for Treatment (Three cassettes) D CAN 254 Minisymposium Clinical Investigations 19: D CAN 226 Thirty-Second G.H.A. Clowes Memorial $23.00 Molecular Biology of Human Cancer II $11.50 Award Lecture: Drug Resistance: (Twocassettes) Genotype versus Phenotype [June L. Biedler] D CAN 255 Symposium 13: Molecular Mechanisms in (One cassette) $23.00 Carcinogenesis (Two cassettes) D CAN 256 Symposium 14: Molecular Approaches to $23.00 Diagnosis and Patient Evaluation CONTINUED. D CAN 257 Minisymposium Immunology 13: Cytokine D CO 215 (SIT3) Cancer in Older Persons $34.50 Modulation of Tumor Growth $11.50 (One cassette) (Three cassettes) D CO 216 (SIT4) Acceptance and Implementation D CAN 258 Minisymposium Preclinlcal $11.50 of New Therapy (One cassette) $34.50 Pharmacology/Experimental Therapeutic« D CO 217 Breast Cancer: Adjuvant Therapies 35: Liposomes in Drug Delivery $34.50 (Three cassettes) (Three cassettes) Q CO 218 Non-Small Cell Lung Cancer/Head and D CAN 259 Minisymposium Carclnogenesis 22: $34.50 Neck Tumors (Three cassettes) $34.50 Mutational Specificity (Three cassettes) D CO 219 Adult Leukemia D CAN 260 Minisymposium Biology 16: Signal $34.50 (Three cassettes) $34.50 Transduction (Three cassettes) D CO 220 Clinical Pharmacology $34.50 (Three cassettes) D CO 221 Pediatrie Solid Tumors $34.50 (Three cassettes) 28th ANNUAL MEETING OF THE AMERICAN D CO 222 Presidential Address and Awards SOCIETY OF CLINICAL ONCOLOGY $11.50 Ceremony [Martin D. Abeloff, MD] (One Cassette) O CO 223 Twenty-Third Annual David A. Karnofsky $11.50 Memorial Lecture: Ode to Methotrexate MAY 17-19, 1992 [Joseph Berlino, MD] (One Cassette) D CO 224 Plenary Session $23.00 (Two Cassettes) D CO 201 (S1) Pain Control in Patients With D CO 225 Breast Cancer: Advanced $11.50 Cancer (One cassette) $34.50 (Three Cassettes) D CO 202 (S2) Ovarian Cancer D CO 226 Gastrointestinal Tract Cancer $11.50 (One cassette) $34.50 (Three Cassettes) D CO 203 (S3) Lung Cancer D CO 227 Genitourinary Tract Cancer $11.50 (One cassette) $34.50 (Three Cassettes) O CO 204 (S4) Molecular Biology D CO 228 Tumor Immunology $11.50 (One cassette) $34.50 (Three Cassettes) D CO 205 (S5) Clinical Pharmacology for the D CO 229 Pediatrie Leukemia and Lymphoma $23.00 Non-Pharmacologist (Two cassettes) $34.50 (Three Cassettes) D CO 206 (S6) Promising New Drugs D CO 230 Small Cell Lung Cancer/Central $11.50 (One cassette) $34.50 Nervous System Tumors (Three Cassettes) D CO 207 (S7) Interpreting the Results of D CO 231 Adult Lymphoma $11.50 Clinical Trials: What do the Data Mean $34.50 (Three Cassettes) to Me? (One cassette) D CO 232 Melanoma/Sarcoma D CO 208 (S8) Futuristic Therapy of Breast $34.50 (Three Cassettes) $11.50 Cancer (One cassette) D CO 233 Gynecological Tumors D CO 209 (S9) Hodgkin's Disease: An Update $34.50 (Three Cassettes) $11.50 (One cassette) D CO 234 Epidemiology/Cancer Prevention and D CO 210 (S10) Myelodysplasia Syndromes in $34.50 Control (Three Cassettes) $11.50 Pediatrie and Adult Patients D CO 235 Cancer Biology and Molecular Genetics (One cassette) $23.00 (Two Cassettes) D CO 211 (S11) Organ Preservation in D CO 236 Lung Cancer (Poster Discussion) $11.50 Multimodality Solid Tumor Therapy $11.50 (One Cassette) (One cassette) D CO 237 Psychosocial Aspects D CO 212 (S12) New Aspects In Early Stage $11.50 (One Cassette) $11.50 Prostate Cancer (One cassette) D CO 213 (SITI) Pediatrie Brain Tumors $11.50 (One cassette) D CO 214 (SIT2) Breast Cancer Prevention With $11.50 Diet and Tamoxifen (One cassette)
DISCOUNTS: Special Offer: 1-5 ..$11.50 Each Buy all 16 Symposia & Special Interest Topic Sessions 6-11 . .5% Discount at a 10% Savings —¿ 12-24 ..10% Discount $765.00 (Regular Price $184.00) 25-48 ..15% Discount 49 or more tapes . .20% Discount
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eventually becoming Director of its Comprehensive Cancer Center and lhal Center's Associate Direclor CancerResearch for Clinical Research. Dr. Berlino is an American Cancer Society Clinical Research Professor and holds many special cancer consultanlships. He is a reviewer for Cancer Research and is currently on the edilorial boards of the International Journal of Cell Cloning and Cancer Investigation. Bert Vogelstein (middle) was recognized for his revolutionary sludies advancing our understanding of the successive mulalions responsible for ihe progres sion of colon cancer. Dr. Vogelstein graduated from the University of Pennsylvania in 1970 and received the M.D. from the Johns Hopkins School of Medicine in 1974. After iwo years al ihe Nalional Cancer Insli- lule (NCI), he returned to Johns Hopkins where he is currently Professor of Oncology. He has been an ad visor lo the NCI and presently serves the Nalional Institutes of Health Scientific Review Groups in this capacity. Dr. Vogelstein is a member of the National Academy of Sciences and the American Academy of Arts and Sciences and has received many awards in Cancer Research is pleased to feature the 1992 re recent years. He is on the review boards of Cancer cipients of the American Cancer Society's most pres Research; Cenes, Chromosomes & Cancer, and Science. tigious award, the Medal of Honor. Each year, the On the same day he received the Medal of Honor, Society honors leaders in basic research and in clinical Dr. Vogelstein was also named an American Cancer research and recognizes the lay contributors to the Society Research Professor. fight against cancer as well. The lay awardee is Roberl Stempel (lower right), Joseph Berlino (upper left) is Chairman of the Mo immediate pasl Chairman of ihe General Motors lecular Pharmacology and Therapeutics Program and Cancer Research Foundation, which has contribuled Chief of the Developmental Chemotherapy Service at greally to the fight against cancer by recognizing and the Memorial Sloan-Kettering Cancer Center. He was rewarding ihe most accomplished and productive can honored for his many contributions in clinical re cer researchers and by helping ihe public lo beller search; his work has led to the introduction worldwide understand importanl advances in the diagnosis, treat of effective new drugs and treatment protocols for ment, and prevention of cancer. Mr. Slempel, former lymphoma, mycosis fungoides, and lung cancer. The Chief Executive Officer and Chairman of the General award also recognized his efforts to gain a better Motors Corporalion, is a dislinguished leader in ihe understanding of antimetabolite action. Dr. Berlino business world. He was represenled al ihe awards graduated from Cornell Universily, received the M.D. ceremony by Joseph G. Forlner, M.D., Presidenl of from the Downstale Medical Center in Brooklyn, and ihe General Molors Cancer Research Foundalion. in 1961 joined the Yale University School of Medi cine. He served as Professor of Pharmacology al Yale. Sidney Weinhouse