Nominations for Breakthrough Prizes in Life Sciences Now Open Online

Total Page:16

File Type:pdf, Size:1020Kb

Nominations for Breakthrough Prizes in Life Sciences Now Open Online Nominations for Breakthrough Prizes in life sciences now open online 04 September 2013 | News | By BioSpectrum Bureau Nominations for Breakthrough Prizes in life sciences now open online The Breakthrough Prize in Life Sciences Foundation recently announced the opening of online nominations for Breakthrough Prizes for 2014. The rules and nomination form are made available in their official site. As per the rules, anyone can nominate a candidate online and all submissions must be completed by a third party. Nominations will be accepted through October 2, 2013. This year the foundation will award up to five prizes worth $3 million each, sponsored by Sergey Brin and Anne Wojcicki, Mark Zuckerberg and Priscilla Chan, and Yuri Milner. All prizes will be awarded for research aimed at curing deadly diseases and extending human life, with special attention to recent discoveries. One prize sponsored by Sergey Brin and Anne Wojcicki is aimed specifically at advancements in Parkinson's disease research. The 2014 prize winners will be chosen by the foundation's selection committee, comprised of prior recipients of the Breakthrough Prize in life sciences, including, Cornelia I. Bargmann, David Botstein, Lewis C. Cantley, Hans Clevers, Napoleone Ferrara, Titia de Lange, Eric S. Lander, Charles L. Sawyers, Bert Vogelstein, Robert A. Weinberg, and Shinya Yamanaka. "We all benefit from the brilliance and commitment of researchers at the frontiers of medical science. This is a chance to reward their achievements and support their future work. If you think someone deserves a Breakthrough Prize, you have the power to put them in the running," said Mr Art Levinson, Chairman of Apple Inc., Genentech, and The Breakthrough Prize in Life Sciences foundation. The Breakthrough Prize in Life Sciences Foundation is a non-profit organization created by Art Levinson, Sergey Brin and Anne Wojcicki, Mark Zuckerberg and Priscilla Chan, and Yuri Milner..
Recommended publications
  • Looking at Earth: an Astronaut's Journey Induction Ceremony 2017
    american academy of arts & sciences winter 2018 www.amacad.org Bulletin vol. lxxi, no. 2 Induction Ceremony 2017 Class Speakers: Jane Mayer, Ursula Burns, James P. Allison, Heather K. Gerken, and Gerald Chan Annual David M. Rubenstein Lecture Looking at Earth: An Astronaut’s Journey David M. Rubenstein and Kathryn D. Sullivan ALSO: How Are Humans Different from Other Great Apes?–Ajit Varki, Pascal Gagneux, and Fred H. Gage Advancing Higher Education in America–Monica Lozano, Robert J. Birgeneau, Bob Jacobsen, and Michael S. McPherson Redistricting and Representation–Patti B. Saris, Gary King, Jamal Greene, and Moon Duchin noteworthy Select Prizes and Andrea Bertozzi (University of James R. Downing (St. Jude Chil- Barbara Grosz (Harvard Univer- California, Los Angeles) was se- dren’s Research Hospital) was sity) is the recipient of the Life- Awards to Members lected as a 2017 Simons Investi- awarded the 2017 E. Donnall time Achievement Award of the gator by the Simons Foundation. Thomas Lecture and Prize by the Association for Computational American Society of Hematology. Linguistics. Nobel Prize in Chemistry, Clara D. Bloomfield (Ohio State 2017 University) is the recipient of the Carol Dweck (Stanford Univer- Christopher Hacon (University 2017 Robert A. Kyle Award for sity) was awarded the inaugural of Utah) was awarded the Break- Joachim Frank (Columbia Univer- Outstanding Clinician-Scientist, Yidan Prize. through Prize in Mathematics. sity) presented by the Mayo Clinic Di- vision of Hematology. Felton Earls (Harvard Univer- Naomi Halas (Rice University) sity) is the recipient of the 2018 was awarded the 2018 Julius Ed- Nobel Prize in Economic Emmanuel J.
    [Show full text]
  • Medical Advisory Board September 1, 2006–August 31, 2007
    hoWard hughes medical iNstitute 2007 annual report What’s Next h o W ard hughes medical i 4000 oNes Bridge road chevy chase, marylaNd 20815-6789 www.hhmi.org N stitute 2007 a nn ual report What’s Next Letter from the president 2 The primary purpose and objective of the conversation: wiLLiam r. Lummis 6 Howard Hughes Medical Institute shall be the promotion of human knowledge within the CREDITS thiNkiNg field of the basic sciences (principally the field of like medical research and education) and the a scieNtist 8 effective application thereof for the benefit of mankind. Page 1 Page 25 Page 43 Page 50 seeiNg Illustration by Riccardo Vecchio Südhof: Paul Fetters; Fuchs: Janelia Farm lab: © Photography Neurotoxin (Brunger & Chapman): Page 3 Matthew Septimus; SCNT images: by Brad Feinknopf; First level of Rongsheng Jin and Axel Brunger; iN Bruce Weller Blake Porch and Chris Vargas/HHMI lab building: © Photography by Shadlen: Paul Fetters; Mouse Page 6 Page 26 Brad Feinknopf (Tsai): Li-Huei Tsai; Zoghbi: Agapito NeW Illustration by Riccardo Vecchio Arabidopsis: Laboratory of Joanne Page 44 Sanchez/Baylor College 14 Page 8 Chory; Chory: Courtesy of Salk Janelia Farm guest housing: © Jeff Page 51 Ways Illustration by Riccardo Vecchio Institute Goldberg/Esto; Dudman: Matthew Szostak: Mark Wilson; Evans: Fred Page 10 Page 27 Septimus; Lee: Oliver Wien; Greaves/PR Newswire, © HHMI; Mello: Erika Larsen; Hannon: Zack Rosenthal: Paul Fetters; Students: Leonardo: Paul Fetters; Riddiford: Steitz: Harold Shapiro; Lefkowitz: capacity Seckler/AP, © HHMI; Lowe: Zack Paul Fetters; Map: Reprinted by Paul Fetters; Truman: Paul Fetters Stewart Waller/PR Newswire, Seckler/AP, © HHMI permission from Macmillan Page 46 © HHMI for Page 12 Publishers, Ltd.: Nature vol.
    [Show full text]
  • 2016 Joint Meeting Program
    April 15 – 17, 2016 Fairmont Chicago Millennium Park • Chicago, Illinois The AAP/ASCI/APSA conference is jointly provided by Boston University School of Medicine and AAP/ASCI/APSA. Meeting Program and Abstracts www.jointmeeting.org www.jointmeeting.org Special Events at the 2016 AAP/ASCI/APSA Joint Meeting Friday, April 15 Saturday, April 16 ASCI President’s Reception ASCI Food and Science Evening 6:15 – 7:15 p.m. 6:30 – 9:00 p.m. Gold Room The Mid-America Club, Aon Center ASCI Dinner & New Member AAP Member Banquet Induction Ceremony (Ticketed guests only) (Ticketed guests only) 7:00 – 10:00 p.m. 7:30 – 9:45 p.m. Imperial Ballroom, Level B2 Rouge, Lobby Level How to Solve a Scientific Puzzle: Speaker: Clara D. Bloomfield, MD Clues from Stockholm and Broadway The Ohio State University Comprehensive Cancer Center Speaker: Joe Goldstein, MD APSA Welcome Reception & University of Texas Southwestern Medical Center at Dallas Presidential Address APSA Dinner (Ticketed guests only) 9:00 p.m. – Midnight Signature Room, 360 Chicago, 7:30 – 9:00 p.m. John Hancock Center (off-site) Rouge, Lobby Level Speaker: Daniel DelloStritto, APSA President Finding One’s Scientific Niche: Musings from a Clinical Neuroscientist Speaker: Helen Mayberg, MD, Emory University Dessert Reception (open to all attendees) 10:00 p.m. – Midnight Imperial Foyer, Level B2 Sunday, April 17 APSA Future of Medicine and www.jointmeeting.org Residency Luncheon Noon – 2:00 p.m. Rouge, Lobby Level 2 www.jointmeeting.org Program Contents General Program Information 4 Continuing Medical Education Information 5 Faculty and Speaker Disclosures 7 Scientific Program Schedule 9 Speaker Biographies 16 Call for Nominations: 2017 Harrington Prize for Innovation in Medicine 26 AAP/ASCI/APSA Joint Meeting Faculty 27 Award Recipients 29 Call for Nominations: 2017 Harrington Scholar-Innovator Award 31 Call for Nominations: George M.
    [Show full text]
  • 2011 Annual Report
    Memorial Sloan-Kettering Cancer Center 2011 Annual Report 10 steps closer 10 steps closer Letter from the Chairman and the President 1 1 | First effective treatments for advanced melanoma 5 2 Genomic analysis offers clues to most common | type of ovarian cancer 7 3 Breast cancer surgery: practice-changing | findings for some patients 9 4 New drugs offer survival benefit for men | with metastatic prostate cancer 11 5 | Insights into DNA damage and repair 13 6 Novel stem cell technique shows promise | in treating disease 15 7 Combination therapy may prevent spread | of nasopharyngeal tumors 17 8 Algorithm can predict shape of proteins, | speeding basic cancer research 19 9 Two of 2011’s top five advances in cancer | research led by MSKCC physician-scientists 21 10 | The Josie Robertson Surgery Center 23 The Campaign for Memorial Sloan-Kettering 25 Statistical Profile 27 Financial Summary 29 Boards of Overseers and Managers 31 www.mskcc.org/annualreport Letter from the Chairman and the President The year 2011 was a strong one at Memorial Sloan-Kettering. We continued to lead across “Our success as an institution is due in the spectrum of patient care, research, and training, and laid the groundwork for important progress in the years ahead. great measure to our remarkable staff… We want to begin by saying that our success as an institution is due in great measure to our remarkable staff. On a daily basis, we are inspired by their dedication and compassion, and We are inspired by their dedication Douglas A. Warner III are grateful for the work they do in the service of our patients and our mission.
    [Show full text]
  • GSA Welcomes 2012 Board Members
    7INTERs3PRING 4HE'3!2EPORTER winter s spring 2012 New Executive GSA Welcomes 2012 Board Members Director Now on Board The Genetics Society of America New Members of the GSA Board of welcomes four new members elected Directors Adam P. Fagen, by the general membership to the Ph.D., stepped in as 2012 GSA Board of Directors. The VICE PRESIDENT: GSA’s new Executive new members are: Michael Lynch Michael Lynch, Director beginning (Indiana University), who serves as Distinguished December 1, 2011. vice president in 2012 and as GSA Professor of Dr. Fagen previously president in 2013 and Marnie E. Biology, Class of was at the American Halpern (Carnegie Institution for 1954 Professor, Society of Plant Science); Mohamed Noor (Duke Department of Biologists (ASPB), University); and John Schimenti Biology, Indiana where he was the director of public (Cornell University), who will serve as University, continued on page nineteen directors. Bloomington. Dr. Lynch is a population and evolutionary biologist and a In addition to these elected officers, long-time member of GSA. Dr. Lynch 2012 Brenda J. Andrews (University of sees GSA as the home for geneticists Toronto), Editor-in-Chief of GSA’s who study a broad base of topics GSA Award journal, G3: Genes|Genomes|Genetics, and organisms, and as a forum Recipients which was first published online in where general discussion occurs, June 2011, becomes a member of the whether based on the principles Announced Board of Directors. The bylaws have of genetics, the most pressing historically included the GENETICS GSA is pleased to announce the issues within the discipline itself, or editor-in-chief on the Board and as a responses to societal concerns and/ 2012 recipients of its five awards result of a 2011 bylaw revision, the G3 for distinguished service in the or conflicts within applied genetics.
    [Show full text]
  • Resubmission JBC Frescas and De Lange
    Cell Biology: Binding of TPP1 Protein to TIN2 Protein Is Required for POT1a,b Protein-mediated Telomere Protection David Frescas and Titia de Lange J. Biol. Chem. 2014, 289:24180-24187. doi: 10.1074/jbc.M114.592592 originally published online July 23, 2014 Downloaded from Access the most updated version of this article at doi: 10.1074/jbc.M114.592592 http://www.jbc.org/ Find articles, minireviews, Reflections and Classics on similar topics on the JBC Affinity Sites. Alerts: • When this article is cited • When a correction for this article is posted at Rockefeller University Library on August 31, 2014 Click here to choose from all of JBC's e-mail alerts This article cites 29 references, 13 of which can be accessed free at http://www.jbc.org/content/289/35/24180.full.html#ref-list-1 THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 289, NO. 35, pp. 24180–24187, August 29, 2014 © 2014 by The American Society for Biochemistry and Molecular Biology, Inc. Published in the U.S.A. Binding of TPP1 Protein to TIN2 Protein Is Required for POT1a,b Protein-mediated Telomere Protection* Received for publication, June 30, 2014, and in revised form, July 22, 2014 Published, JBC Papers in Press, July 23, 2014, DOI 10.1074/jbc.M114.592592 David Frescas and Titia de Lange1 From the Laboratory for Cell Biology and Genetics, The Rockefeller University, New York, New York 10065 Background: Chromosome ends require the TPP1/POT1 heterodimers for protection. Results: A TIN2 mutant that fails to bind TPP1 resulted in phenotypes associated with TPP1/POT1 deletion.
    [Show full text]
  • Science & Policy Meeting Jennifer Lippincott-Schwartz Science in The
    SUMMER 2014 ISSUE 27 encounters page 9 Science in the desert EMBO | EMBL Anniversary Science & Policy Meeting pageS 2 – 3 ANNIVERSARY TH page 8 Interview Jennifer E M B O 50 Lippincott-Schwartz H ©NI Membership expansion EMBO News New funding for senior postdoctoral In perspective Georgina Ferry’s enlarges its membership into evolution, researchers. EMBO Advanced Fellowships book tells the story of the growth and ecology and neurosciences on the offer an additional two years of financial expansion of EMBO since 1964. occasion of its 50th anniversary. support to former and current EMBO Fellows. PAGES 4 – 6 PAGE 11 PAGES 16 www.embo.org HIGHLIGHTS FROM THE EMBO|EMBL ANNIVERSARY SCIENCE AND POLICY MEETING transmissible cancer: the Tasmanian devil facial Science meets policy and politics tumour disease and the canine transmissible venereal tumour. After a ceremony to unveil the 2014 marks the 50th anniversary of EMBO, the 45th anniversary of the ScienceTree (see box), an oak tree planted in soil European Molecular Biology Conference (EMBC), the organization of obtained from countries throughout the European member states who fund EMBO, and the 40th anniversary of the European Union to symbolize the importance of European integration, representatives from the govern- Molecular Biology Laboratory (EMBL). EMBO, EMBC, and EMBL recently ments of France, Luxembourg, Malta, Spain combined their efforts to put together a joint event at the EMBL Advanced and Switzerland took part in a panel discussion Training Centre in Heidelberg, Germany, on 2 and 3 July 2014. The moderated by Marja Makarow, Vice President for Research of the Academy of Finland.
    [Show full text]
  • Humankind 2.0: the Technologies of the Future 6. Biotech
    Humankind 2.0: The Technologies of the Future 6. Biotech Piero Scaruffi, 2017 See http://www.scaruffi.com/singular/human20.html for the full text of this discussion A brief History of Biotech 1953: Discovery of the structure of the DNA 2 A brief History of Biotech 1969: Jon Beckwith isolates a gene 1973: Stanley Cohen and Herbert Boyer create the first recombinant DNA organism 1974: Waclaw Szybalski coins the term "synthetic biology” 1975: Paul Berg organizes the Asilomar conference on recombinant DNA 3 A brief History of Biotech 1976: Genentech is founded 1977: Fred Sanger invents a method for rapid DNA sequencing and publishes the first full DNA genome of a living being Janet Rossant creates a chimera combining two mice species 1980: Genentech’s IPO, first biotech IPO 4 A brief History of Biotech 1982: The first biotech drug, Humulin, is approved for sale (Eli Lilly + Genentech) 1983: Kary Mullis invents the polymerase chain reaction (PCR) for copying genes 1986: Leroy Hood invents a way to automate gene sequencing 1986: Mario Capecchi performs gene editing on a mouse 1990: William French Anderson’s gene therapy 1990: First baby born via PGD (Alan Handyside’s lab) 5 A brief History of Biotech 1994: FlavrSavr Tomato 1994: Maria Jasin’s homing endonucleases for genome editing 1996: Srinivasan Chandrasegaran’s ZFN method for genome editing 1996: Ian Wilmut clones the first mammal, the sheep Dolly 1997: Dennis Lo detects fetal DNA in the mother’s blood 2000: George Davey Smith introduces Mendelian randomization 6 A brief History of Biotech
    [Show full text]
  • CRISPR-Cas Arxiv:1712.09865V2 [Q-Bio.PE] 26 Mar 2018
    The physicist's guide to one of biotechnology's hottest new topics: CRISPR-Cas Melia E. Bonomo1;3 and Michael W. Deem1;2;3 1Department of Physics and Astronomy, Rice University, Houston, TX 77005, USA 2Department of Bioengineering, Rice University, Houston, TX 77005, USA 3Center for Theoretical Biological Physics, Rice University, Houston, TX 77005, USA Contents 1 Introduction 3 2 Three stages of immunity 4 2.1 Adaptation . 6 2.2 Expression . 7 2.3 Interference . 8 3 Molecular memory cassettes 9 3.1 Timing and origin of acquired spacers . 10 3.2 Experimental studies of spacer diversity . 11 3.3 Modeling spacer diversity in the CRISPR locus . 12 3.4 Effects of spacer acquisition and deletion rates . 14 3.5 Timescale of spacer expression . 17 4 Horizontal gene transfer 17 4.1 Acquisition of CRISPR loci and spacers . 18 arXiv:1712.09865v2 [q-bio.PE] 26 Mar 2018 4.2 CRISPR-Cas restriction of HGT . 19 4.3 Persistent HGT . 20 5 Specificity 21 5.1 Cas specificity and conformational changes . 21 5.2 Identifying CRISPR-Cas PAMs . 24 5.3 Self and non-self discrimination . 25 5.4 Cross-reactivity . 26 5.5 Profiling Cas9 off-target activity . 27 1 6 Evolution and abundance of CRISPR loci 29 6.1 Support for a Lamarckian-type evolution . 29 6.2 Strain divergence . 31 6.3 Selection pressure for survival of the cell . 33 6.4 Impact of effectiveness . 34 7 Cost and regulation of CRISPR Activity 35 7.1 Spacer maintenance considerations . 36 7.2 Turning CRISPR on and off .
    [Show full text]
  • Anti-Angiogenic Drugs to Treat Human Disease: an Interview with Napoleone Ferrara
    Disease Models & Mechanisms 2, 324-325 (2009) doi:10.1242/dmm.002972 A MODEL FOR LIFE Published by The Company of Biologists 2009 Anti-angiogenic drugs to treat human disease: an interview with Napoleone Ferrara Napoleone Ferrara identified vascular endothelial growth factor (VEGF) as a major regulator of blood vessel development. The antibodies that he and his colleagues created to block VEGF action also block cancer growth. Here, he discusses the work that led to the development of the anti-cancer drug Avastin (bevacizumab), and discusses the role of basic science in clinical medicine. he formation of new blood But none of the molecules that were ini- vessels, or angiogenesis, is neces- tially characterized as potential angiogenic sary for the development of most factors seemed to be important as endoge- multicellular organisms. The new nous regulators. For example, basic fibrob- vessels allow for the perfusion of last growth factor (bFGF) was one of the Torgans and tissues, including those involved first factors to be purified and characterized in normal embryonic development, repro- as an angiogenic factor. It was extremely ductive function and skeletal growth. potent in several in vitro and in vivo DMM However, promoting blood vessel develop- systems, but then when researchers tried to ment also allows tumors to obtain neces- block bFGF function with antibodies, it had sary nutrients and survival factors and to little effect on tumor growth. Even the eliminate catabolic products. In 2004, Dr knockout of the gene for bFGF did not Ferrara’s work at Genentech led to the first result in any obvious defect in vascular de- Food and Drug Administration (FDA) ap- velopment, so clearly something was genic factor that regulated blood vessel for- proval of the anti-VEGF antibody, under the missing.
    [Show full text]
  • Prize Winner Announcement
    Contact: Seema Kumar Janssen Pharmaceutical Companies of Johnson & Johnson 908-218-6460 or [email protected] Diane Pressman Janssen Pharmaceutical Companies of Johnson & Johnson 908-927-6171 or [email protected] Frederik Wittock Janssen Pharmaceutical Companies of Johnson & Johnson +32 14 60 57 24 or [email protected] Dr. Napoleone Ferrara Wins 2011 Dr. Paul Janssen Award for Biomedical Research Discovery Unlocked Key to Novel Anti-angiogenesis Therapies Washington, DC – June 28, 2011 – Johnson & Johnson today announced the winner of the 2011 Dr. Paul Janssen Award for Biomedical Research during the BIO International Convention (BIO) in Washington D.C. Napoleone Ferrara, M.D., is the seventh leading scientist to win the Award, which honors a scientist or team of scientists whose contributions have the potential to significantly improve the health and lives of people around the world. Dr. Ferrara was selected by an independent committee of eight renowned scientists, including Nobel Laureates, Lasker Prize winners, and others, for his research on angiogenesis, the process of new blood vessel formation that plays a key role in cancer proliferation and a number of other diseases. Dr. Ferrara’s discoveries opened the door to the development of a new class of therapeutics to combat a serious eye disorder and contributed to the development of new oncology therapeutics. “With the 2011 Dr. Paul Janssen Award for Biomedical Research, Johnson & Johnson recognizes Dr. Ferrara for the meaningful impact his discoveries have had on the lives of patients all over the world,” said Paul Stoffels, M.D., Worldwide Chairman, Pharmaceuticals, Johnson & Johnson. “Like Dr.
    [Show full text]
  • Progam Book Final(210 X 297Mm封面)
    GuangzhouGuangzhou InternationalInternational VascularVascular BiologyBiology ConferenceConference June 25, 2017 Organized by: Zhongshan Opthalmic Center, Sun Yat-sen University State Key Laboratory of Ophthalmology Welcome Acknowledgement Dear Colleagues and Friends, On behalf of the Chinese Vascular Biology Organization (CVBO), we are delighted to welcome you to our first International Vascular Biology Conference in Guangzhou, China. With the boost of economy, education and sciences in China in the past twenty years and a growing number of researchers returned to China from abroad, research in vascular biology in China is catching up and has made important contributions to the field, which promises a better progress in both basic and translational research in the future. The goals of this conference are to promote vascular biology research by establishing a platform for researchers and trainees to share and exchange cutting edge knowledge in vascular biology, and to boost communication, collaboration and education. We hereby welcome you to the beautiful city of Guangzhou, the “City of Flowers”, and hope that you will enjoy the great food and beautiful scenes of Guangzhou. We wish you a productive and enjoyable conference while staying in Guangzhou! Sincerely, Dr. Napoleone Ferrara Dr. Yizhi Liu Dr. Xuri Li 01 Guangzhou International Vascular Biology Conference 2017 The Zhongshan Ophthalmic Center (ZOC) The Zhongshan Ophthalmic Center (ZOC) is affiliated to Sun Yat-sen University in Guangzhou, the southern gateway to China. Since its inception in 1983, ZOC has been the largest eye care center in China. ZOC consists of three components: the Affiliated Ophthalmic Hospital, the Ophthalmic Research Institute, and the Department of Blindness Prevention.
    [Show full text]