DOCSLIB.ORG

Progam Book Final（210 X 297Mm封面）

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Progam Book Final（210 X 297Mm封面） GuangzhouGuangzhou InternationalInternational VascularVascular BiologyBiology ConferenceConference June 25, 2017 Organized by: Zhongshan Opthalmic Center, Sun Yat-sen University State Key Laboratory of Ophthalmology Welcome Acknowledgement Dear Colleagues and Friends, On behalf of the Chinese Vascular Biology Organization (CVBO), we are delighted to welcome you to our first International Vascular Biology Conference in Guangzhou, China. With the boost of economy, education and sciences in China in the past twenty years and a growing number of researchers returned to China from abroad, research in vascular biology in China is catching up and has made important contributions to the field, which promises a better progress in both basic and translational research in the future. The goals of this conference are to promote vascular biology research by establishing a platform for researchers and trainees to share and exchange cutting edge knowledge in vascular biology, and to boost communication, collaboration and education. We hereby welcome you to the beautiful city of Guangzhou, the “City of Flowers”, and hope that you will enjoy the great food and beautiful scenes of Guangzhou. We wish you a productive and enjoyable conference while staying in Guangzhou! Sincerely, Dr. Napoleone Ferrara Dr. Yizhi Liu Dr. Xuri Li 01 Guangzhou International Vascular Biology Conference 2017 The Zhongshan Ophthalmic Center (ZOC) The Zhongshan Ophthalmic Center (ZOC) is affiliated to Sun Yat-sen University in Guangzhou, the southern gateway to China. Since its inception in 1983, ZOC has been the largest eye care center in China. ZOC consists of three components: the Affiliated Ophthalmic Hospital, the Ophthalmic Research Institute, and the Department of Blindness Prevention. ZOC has more than 300 ophthalmologists and offers a full spectrum of tertiary subspecialty care for common and complicated eye diseases. In 2016, ZOC has managed an annual workload of 1,010,000 outpatient visits and more than 60,000 surgeries. In addition, the State Key Laboratory for Ophthalmology (SKLO), the only one of its kind in China, is hosted by ZOC. ZOC has actively participated in international academic events for years. In 2015, the Asia Pacific Academy of Ophthalmology (APAO) set its permanent headquarter at ZOC in the Zhujiang New Town. In 2014, the Nature Magazine Chinese Forum was held in ZOC in Guangzhou. In 2015, the Congress of the Asia Pacific Academy of Ophthalmology had its annual conference at ZOC. ZOC has also established collaborations with many institutions and organizations, such as the WHO, Johns Hopkins University and NIH/NEI. ZOC has taken on arduous tasks, carried forward our predecessors’ legacy and opened up new vistas in ophthalmology in China. ZOC strives to become one of the leading ophthalmic centers in the world. 02 The State Key Laboratory of Ophthalmology (SKLO) at ZOC The State Key Laboratory of Ophthalmology (SKLO) is the only one of its kind in China, and is established by the Ministry of Science and Technology of the Chinese government. The history of SKLO is very closely related to the first Western eye hospital in China established in 1835 in Guangzhou. The SKLO is currently led by Professor Yizhi Liu, an internationally recognized doctor and scientist in the field of stem cell and developmental biology. SKLO has more than 50 researchers, who actively conduct both basic and translational research in the fields of stem cell and developmental biology, neurobiology, vascular biology, immunology, gene therapy, ophthalmic diseases, etc, resulting in publication in the journals of Nature, JAMA, Science, PNAS, and Ophthalmology, etc. In 2016, the study on stem cell-mediated lens repair from Prof. Yizhi Liu’s team was recognized as one of the top 8 notable advances in the field of life sciences by Nature Medicine. SKLO’s goals are to advance our knowledge on the visual system in health and diseases, preserve and restore vision, and ultimately improve the quality of life. 03 Guangzhou International Vascular Biology Conference 2017 Conference information 会议地址：中山大学中山眼科中心珠江新城院区科技楼二楼学术报告厅 Conference Venue: Academic hall, 2F, Science Building, Zhongshan Opthalmic Center, Sun Yat-sen University, No.7 Jinsui Road, Zhujiang New Town, Tianhe District , Guangzhou, China 无线网络：sysuzoc；密码：ykzx8733 Wifi: sysuzoc, Key: ykzx8733 酒店地址：广州市天河区珠江新城金穗路5号威珀斯酒店 电话：188 1396 6176 (谭经理), 020 - 3893 3888 Hotel venue: Vaperse Hotel, No.5 Jinsui Road, Zhujiang New Town, Tianhe District, Guangzhou Tel: 188 1396 6176, 020 - 3893 3888 早餐：威珀斯酒店2楼帕萃美食餐厅 电话：188 1396 6176 (谭经理), 020 - 80732998 Breakfast: 2Fl, Peturs Restaurant, Vaperse Hotel Tel: 188 1396 6176, 020 - 8073 2998 04 Conference Program 8:30 AM – 5 PM Sunday, June 25, 2017 State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Jinsui Road 7, Zhujiang New Town, Guangzhou, China Morning Session Chairs: Jan Kitajewski, Zhongjun Zhou 8:50am - 9:00am Opening welcome Yizhi Liu, SKLO, Zhongshan Ophthalmic Center (ZOC), Sun Yat-Sen University 9:00am - 9:30am Novel insights in the regulation of angiogenesis Napoleone Ferrara, University of California, San Diego, USA 9:30am - 9:40am Discussion 9:40am - 10:10am Conbercept: from lab to bed Michael Yu, Innovent Biologics, Inc 10:10am - 10:20am Discussion 10:20am - 10:35am Coffee/tea break 10:35am - 11:05am Novel roles of VEGF-B in angiogenesis Xuri Li, SKLO, Zhongshan Ophthalmic Center (ZOC), Sun Yat-Sen University 05 Guangzhou International Vascular Biology Conference 2017 11:05am - 11:15am Discussion 11:15pm - 11:30pm Effect of PDGF-C on mouse embryonic stem cells Weisi Lu, Zhongshan Ophthalmic Center (ZOC), Sun Yat-Sen University 11:30pm - 11:35pm Discussion 11:35pm - 11:50pm Function and Mechanisms of Mig6 in angiogenesis Chunsik Lee, Zhongshan Ophthalmic Center (ZOC), Sun Yat-Sen University 11:50pm - 11:55pm Discussion 12:00pm - 1:45 pm Lunch Afternoon Session Chairs: Napoleone Ferrara, Michael Yu, Xuri Li 2:00pm - 2:30pm Notch functions in angiogenesis by diverse mechanisms Jan Kitajewski, University of Illinois Chicago, USA 2:30pm - 2:40pm Discussion 2:40pm - 3:10pm MT1-MMP is a critical regulator of lymphangiogenesis Zhongjun Zhou, The University of Hong Kong 3:10pm - 3:20pm Discussion 3:20pm - 3:35pm Effect of VEGF-B on insulin secretion Geng Tian, Binzhou Medical University 3:35pm - 3:40pm Discussion 06 3:40pm - 3:55pm PDGF-B signaling network in carcinogenesis Jia Mi, Binzhou Medical University 3:55pm - 4:00pm Discussion 4:00pm - 4:15pm Coffee/tea break 4:15pm - 4:30pm Function of VEGFRs in retinal pigment epithelial cells Rong Ju, Zhongshan Ophthalmic Center (ZOC), Sun Yat-Sen University 4:30pm - 4:35pm Discussion 4:35pm - 4:50pm Protective effect of Caveolin-1 on Retinal Ganglion Cells Zhongshu Tang, Zhongshan Ophthalmic Center (ZOC), Sun Yat-Sen University 4:50pm - 4:55pm Discussion 07 Guangzhou International Vascular Biology Conference 2017 Introduction of Lecturers Yizhi Liu,M.D., Ph.D. Napoleone Ferrara, M.D. Michael Yu, Ph.D. Jan Kitajewski, Ph.D. Zhongjun Zhou, Ph.D. Xuri Li, Ph.D. Chunsik Lee, Ph.D. Rong Ju, Ph.D. Zhongshu Tang, Ph.D. Geng Tian, Ph.D. Jia Mi, Ph.D. Weisi Lu, Ph.D. 08 Introduction of Lecturers Yizhi Liu,M.D., Ph.D. Zhongshan Ophthalmic Center, Sun Yat-Sen University Dr.Yizhi Liu has served as the director of the Zhongshan Ophthalmic Center, Sun Yat-sen University since Feb 2012. He has been elected to the standing committee member of Asia-Pacific Academy of Ophthalmology (APAO) and Chairman of Ophthalmology Association of Guangdong Province, as well as Editor-in-Chief of Molecular Vision and Associate Editor-in-Chief of Current Molecular Medicine. Dr. Liu has been admitted as the chief scientist with his research project granted by the National Program on Key Basic Research Project (973 Program), and has published more than 60 peer-reviewed papers to date in international scientific journals such as Nature, Proc Natl Acad Sci and OPHTHALMOLOGY. Dr. Liu is focusing on the regulatory mechanisms of ocular stem cells activation, proliferation and differentiation during the process of eye development and regeneration, as well as exploring their potential in the repair of damaged eye tissues and treatment of blinding disease. Representative Publications 1. Lin H, Ouyang H, Zhu J, Huang S, Liu Z, Chen S, Cao G, Li G, Signer RA, Xu Y, Chung C, Zhang Y, Lin D, Patel S, Wu F, Cai H, Hou J, Wen C, Jafari M, Liu X, Luo L, Zhu J, Qiu A, Hou R, Chen B, Chen J, Granet D, Heichel C, Shang F, Li X, Krawczyk M, Skowronska-Krawczyk D, Wang Y, Shi W, Chen D, Zhong Z, Zhong S, Zhang L, Chen S, Morrison SJ, Maas RL, Zhang K*, Liu Y*. Lens regeneration using endogenous stem cells with gain of visual function. Nature. 2016 Mar 17;531(7594):323-8. 2. Zhao L, Chen XJ, Zhu J, Xi YB, Yang X, Hu LD, Ouyang H, Patel SH, Jin X, Lin D, Wu F, Flagg K, Cai H, Li G, Cao G, Lin Y, Chen D, Wen C, Chung C, Wang Y, Qiu A, Yeh E, Wang W, Hu X, Grob S, Abagyan R, Su Z, Tjondro HC, Zhao XJ, Luo H, Hou R, Jefferson J, Perry P, Gao W, Kozak I, Granet D, Li Y, Sun X, Wang J, Zhang L, Liu Y, Yan YB, Zhang K. Lanosterol reverses protein aggregation in cataracts. Nature. 2015 Jul 30;523(7562):607-11. 3. Ouyang H, Xue Y, Lin Y, Zhang X, Xi L, Patel S, Cai H, Luo J, Zhang M, Zhang M, Yang Y, Li G, Li H, Jiang W, Yeh E, Lin J, Pei M, Zhu J,Cao G, Zhang L, Yu B, Chen S, Fu XD, Liu Y*,Zhang K. WNT7A and PAX6 define corneal epithelium homeostasis and pathogenesis. Nature. 2014 Jul 17;511(7509):358-61. 4. Gong L, Ji WK, Hu XH, Hu WF, Tang XC, Huang ZX, Li L, Liu M, Xiang SH, Wu E, Woodward Z, Liu YZ*, Nguyen QD*, Li DW*.
Load more

Recommended publications
  • Anti-Angiogenic Drugs to Treat Human Disease: an Interview with Napoleone Ferrara
    Disease Models & Mechanisms 2, 324-325 (2009) doi:10.1242/dmm.002972 A MODEL FOR LIFE Published by The Company of Biologists 2009 Anti-angiogenic drugs to treat human disease: an interview with Napoleone Ferrara Napoleone Ferrara identified vascular endothelial growth factor (VEGF) as a major regulator of blood vessel development. The antibodies that he and his colleagues created to block VEGF action also block cancer growth. Here, he discusses the work that led to the development of the anti-cancer drug Avastin (bevacizumab), and discusses the role of basic science in clinical medicine. he formation of new blood But none of the molecules that were ini- vessels, or angiogenesis, is neces- tially characterized as potential angiogenic sary for the development of most factors seemed to be important as endoge- multicellular organisms. The new nous regulators. For example, basic fibrob- vessels allow for the perfusion of last growth factor (bFGF) was one of the Torgans and tissues, including those involved first factors to be purified and characterized in normal embryonic development, repro- as an angiogenic factor. It was extremely ductive function and skeletal growth. potent in several in vitro and in vivo DMM However, promoting blood vessel develop- systems, but then when researchers tried to ment also allows tumors to obtain neces- block bFGF function with antibodies, it had sary nutrients and survival factors and to little effect on tumor growth. Even the eliminate catabolic products. In 2004, Dr knockout of the gene for bFGF did not Ferrara’s work at Genentech led to the first result in any obvious defect in vascular de- Food and Drug Administration (FDA) ap- velopment, so clearly something was genic factor that regulated blood vessel for- proval of the anti-VEGF antibody, under the missing.
    [Show full text]
  • Prize Winner Announcement
    Contact: Seema Kumar Janssen Pharmaceutical Companies of Johnson & Johnson 908-218-6460 or [email protected] Diane Pressman Janssen Pharmaceutical Companies of Johnson & Johnson 908-927-6171 or [email protected] Frederik Wittock Janssen Pharmaceutical Companies of Johnson & Johnson +32 14 60 57 24 or [email protected] Dr. Napoleone Ferrara Wins 2011 Dr. Paul Janssen Award for Biomedical Research Discovery Unlocked Key to Novel Anti-angiogenesis Therapies Washington, DC – June 28, 2011 – Johnson & Johnson today announced the winner of the 2011 Dr. Paul Janssen Award for Biomedical Research during the BIO International Convention (BIO) in Washington D.C. Napoleone Ferrara, M.D., is the seventh leading scientist to win the Award, which honors a scientist or team of scientists whose contributions have the potential to significantly improve the health and lives of people around the world. Dr. Ferrara was selected by an independent committee of eight renowned scientists, including Nobel Laureates, Lasker Prize winners, and others, for his research on angiogenesis, the process of new blood vessel formation that plays a key role in cancer proliferation and a number of other diseases. Dr. Ferrara’s discoveries opened the door to the development of a new class of therapeutics to combat a serious eye disorder and contributed to the development of new oncology therapeutics. “With the 2011 Dr. Paul Janssen Award for Biomedical Research, Johnson & Johnson recognizes Dr. Ferrara for the meaningful impact his discoveries have had on the lives of patients all over the world,” said Paul Stoffels, M.D., Worldwide Chairman, Pharmaceuticals, Johnson & Johnson. “Like Dr.
    [Show full text]
  • Lasker Interactive Research Nom'18.Indd
    THE 2018 LASKER MEDICAL RESEARCH AWARDS Nomination Packet albert and mary lasker foundation November 1, 2017 Greetings: On behalf of the Albert and Mary Lasker Foundation, I invite you to submit a nomination for the 2018 Lasker Medical Research Awards. Since 1945, the Lasker Awards have recognized the contributions of scientists, physicians, and public citizens who have made major advances in the understanding, diagnosis, treatment, cure, and prevention of disease. The Medical Research Awards will be offered in three categories in 2018: Basic Research, Clinical Research, and Special Achievement. The Lasker Foundation seeks nominations of outstanding scientists; nominations of women and minorities are encouraged. Nominations that have been made in previous years are not automatically reconsidered. Please see the Nomination Requirements section of this booklet for instructions on updating and resubmitting a nomination. The Foundation accepts electronic submissions. For information on submitting an electronic nomination, please visit www.laskerfoundation.org. Lasker Awards often presage future recognition of the Nobel committee, and they have become known popularly as “America’s Nobels.” Eighty-seven Lasker laureates have received the Nobel Prize, including 40 in the last three decades. Additional information on the Awards Program and on Lasker laureates can be found on our website, www.laskerfoundation.org. A distinguished panel of jurors will select the scientists to be honored with Lasker Medical Research Awards. The 2018 Awards will
    [Show full text]
  • Michel Foucault Ronald C Kessler Graham Colditz Sigmund Freud
    ANK RESEARCHER ORGANIZATION H INDEX CITATIONS 1 Michel Foucault Collège de France 296 1026230 2 Ronald C Kessler Harvard University 289 392494 3 Graham Colditz Washington University in St Louis 288 316548 4 Sigmund Freud University of Vienna 284 552109 Brigham and Women's Hospital 5 284 332728 JoAnn E Manson Harvard Medical School 6 Shizuo Akira Osaka University 276 362588 Centre de Sociologie Européenne; 7 274 771039 Pierre Bourdieu Collège de France Massachusetts Institute of Technology 8 273 308874 Robert Langer MIT 9 Eric Lander Broad Institute Harvard MIT 272 454569 10 Bert Vogelstein Johns Hopkins University 270 410260 Brigham and Women's Hospital 11 267 363862 Eugene Braunwald Harvard Medical School Ecole Polytechnique Fédérale de 12 264 364838 Michael Graetzel Lausanne 13 Frank B Hu Harvard University 256 307111 14 Yi Hwa Liu Yale University 255 332019 15 M A Caligiuri City of Hope National Medical Center 253 345173 16 Gordon Guyatt McMaster University 252 284725 17 Salim Yusuf McMaster University 250 357419 18 Michael Karin University of California San Diego 250 273000 Yale University; Howard Hughes 19 244 221895 Richard A Flavell Medical Institute 20 T W Robbins University of Cambridge 239 180615 21 Zhong Lin Wang Georgia Institute of Technology 238 234085 22 Martín Heidegger Universität Freiburg 234 335652 23 Paul M Ridker Harvard Medical School 234 318801 24 Daniel Levy National Institutes of Health NIH 232 286694 25 Guido Kroemer INSERM 231 240372 26 Steven A Rosenberg National Institutes of Health NIH 231 224154 Max Planck
    [Show full text]
  • 2014 Annual Report Letter from the CHAIR and President
    LASKER FOUNDATION 2014 Annual Report LETTER FROM THE CHAIR AND PRESIDENT HE Lasker FOUNDATION is committed to improving health by inspiring support for medical research. We shine a light on outstanding advances that improve health and spread the word that The mission of the Albert and Mary Lasker Foundation T great science needs broad-based support in order to thrive. The Lasker Foundation believes that it is critical to educate people everywhere that is to improve health by accelerating support for MIKE OVERLOCK Chair investments in medical research yield valuable returns in the form of treatments for Albert and Mary Lasker Foundation debilitating disorders, new means of preventing diseases, and improved quality of life. medical research through recognition of research excellence, This is a very exciting time for the Lasker Foundation. The Lasker Awards continue to draw international attention to the powerful advances being made in research. We are spearheading a number of new educational initiatives that bring informa- public education and advocacy. tion about health and science to the public. And our growing advocacy work is more important than ever as NIH and other federal funding for research continues to lose purchasing power. The success of our work at the Lasker Foundation is buoyed by the support we CLAIRE PomeroY, MD, MBA President receive from you and the many others who are dedicated to our mission. Together Albert and Mary Lasker Foundation we can achieve our vision of a healthier world through medical research. Video: The Lasker Legacy http://vimeo.com/104527849 3 LASKER AWARDS PROGRAM Please join us in congratulating our Lasker Award winners.
    [Show full text]
  • Jennifer Doudna, Ph.D., and Emmanuelle Charpentier, Ph.D., Win 2014 Dr
    Contact: Seema Kumar 732-524-2646 [email protected] Diane Pressman 908-927-6171 [email protected] Frederik Wittock +32 14 60 57 24 [email protected] Jennifer Doudna, Ph.D., and Emmanuelle Charpentier, Ph.D., Win 2014 Dr. Paul Janssen Award for Biomedical Research SAN DIEGO – June 24, 2014 – Johnson & Johnson today named Dr. Jennifer Doudna of the the University of California, Berkeley, and Dr. Emmanuelle Charpentier, of the Hannover Medical School and Helmholtz Centre for Infection Research (HZI), Germany and The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Sweden, the winners of the 2014 Dr. Paul Janssen Award for Biomedical Research. Their collaboration led to the discovery of a new method for precisely manipulating genetic information in ways that should produce new insights in health and disease, and may lead to the discovery of new targets for drug development. “Their discovery of this new DNA editing strategy is considered one of the most significant breakthroughs in molecular biology in the past decade,” said Paul Stoffels, MD, Chief Scientific Officer, Johnson & Johnson. “We are pleased to be able to recognize two researchers whose insights, persistence and collaboration have led to a significant leap in our understanding and ability to manipulate genetic processes. The work of Drs. Doudna and Charpentier has the potential to make a significant impact on human health, which is the very heart of Dr. Paul’s legacy, as well as our mission at Johnson & Johnson.” The Dr. Paul Janssen Award for Biomedical Research was created by Johnson & Johnson to honor the legacy of one of the most passionate, creative and productive scientists of the 20th century, Dr.
    [Show full text]
  • Nominations for Breakthrough Prizes in Life Sciences Now Open Online
    Nominations for Breakthrough Prizes in life sciences now open online 04 September 2013 | News | By BioSpectrum Bureau Nominations for Breakthrough Prizes in life sciences now open online The Breakthrough Prize in Life Sciences Foundation recently announced the opening of online nominations for Breakthrough Prizes for 2014. The rules and nomination form are made available in their official site. As per the rules, anyone can nominate a candidate online and all submissions must be completed by a third party. Nominations will be accepted through October 2, 2013. This year the foundation will award up to five prizes worth $3 million each, sponsored by Sergey Brin and Anne Wojcicki, Mark Zuckerberg and Priscilla Chan, and Yuri Milner. All prizes will be awarded for research aimed at curing deadly diseases and extending human life, with special attention to recent discoveries. One prize sponsored by Sergey Brin and Anne Wojcicki is aimed specifically at advancements in Parkinson's disease research. The 2014 prize winners will be chosen by the foundation's selection committee, comprised of prior recipients of the Breakthrough Prize in life sciences, including, Cornelia I. Bargmann, David Botstein, Lewis C. Cantley, Hans Clevers, Napoleone Ferrara, Titia de Lange, Eric S. Lander, Charles L. Sawyers, Bert Vogelstein, Robert A. Weinberg, and Shinya Yamanaka. "We all benefit from the brilliance and commitment of researchers at the frontiers of medical science. This is a chance to reward their achievements and support their future work. If you think someone deserves a Breakthrough Prize, you have the power to put them in the running," said Mr Art Levinson, Chairman of Apple Inc., Genentech, and The Breakthrough Prize in Life Sciences foundation.
    [Show full text]
  • 2018-01-03-Dr. Paul Janssen Award for Biomedical Research Issues
    Press Contacts: Dr. Paul Janssen Award for Biomedical Research Issues 2018 Call for Nominations to Celebrate Champions of Science Seema Kumar 908-405-1144 (M) [email protected] New Brunswick, N.J. – January 3, 2018 – Nominations are now being accepted for the 2018 Dr. Paul Janssen Award for Biomedical Research. This prestigious award Diane Pressman 908-927-6171 (O) celebrates today’s most dedicated researchers and champions of science whose [email protected] basic or clinical discoveries have made, or have the potential to make, significant contributions toward improving human health. Nominations will be accepted until February 28, 2018 at www.pauljanssenaward.com for consideration by an independent selection committee of world-renowned scientists. A $200,000 cash prize will be awarded to the scientist or group of scientists receiving the Award. The Dr. Paul Janssen Award for Biomedical Research honors Dr. Paul Janssen (1926-2003), one of the most productive pharmaceutical scientists of the 20th century, who was responsible for breakthrough treatments in key disease areas including pain management, psychiatry, infectious disease and gastroenterology. Janssen founded Janssen Pharmaceutica, N.V., now part of the Johnson & Johnson Family of Companies. “Behind every discovery that holds the promise for saving and improving lives are the scientists who pursue a vision and work tirelessly for many years to make it all possible,” said Paul Stoffels, M.D., Chief Scientific Officer, Johnson & Johnson. “We are proud to honor the legacy of Dr. Paul by recognizing the outstanding researchers and champions of science who make a lasting impact on our world.” In 2017, the Dr.
    [Show full text]
  • Acknowledgment of Reviewers, 2009
    Proceedings of the National Academy ofPNAS Sciences of the United States of America www.pnas.org Acknowledgment of Reviewers, 2009 The PNAS editors would like to thank all the individuals who dedicated their considerable time and expertise to the journal by serving as reviewers in 2009. Their generous contribution is deeply appreciated. A R. Alison Adcock Schahram Akbarian Paul Allen Lauren Ancel Meyers Duur Aanen Lia Addadi Brian Akerley Phillip Allen Robin Anders Lucien Aarden John Adelman Joshua Akey Fred Allendorf Jens Andersen Ruben Abagayan Zach Adelman Anna Akhmanova Robert Aller Olaf Andersen Alejandro Aballay Sarah Ades Eduard Akhunov Thorsten Allers Richard Andersen Cory Abate-Shen Stuart B. Adler Huda Akil Stefano Allesina Robert Andersen Abul Abbas Ralph Adolphs Shizuo Akira Richard Alley Adam Anderson Jonathan Abbatt Markus Aebi Gustav Akk Mark Alliegro Daniel Anderson Patrick Abbot Ueli Aebi Mikael Akke David Allison David Anderson Geoffrey Abbott Peter Aerts Armen Akopian Jeremy Allison Deborah Anderson L. Abbott Markus Affolter David Alais John Allman Gary Anderson Larry Abbott Pavel Afonine Eric Alani Laura Almasy James Anderson Akio Abe Jeffrey Agar Balbino Alarcon Osborne Almeida John Anderson Stephen Abedon Bharat Aggarwal McEwan Alastair Grac¸a Almeida-Porada Kathryn Anderson Steffen Abel John Aggleton Mikko Alava Genevieve Almouzni Mark Anderson Eugene Agichtein Christopher Albanese Emad Alnemri Richard Anderson Ted Abel Xabier Agirrezabala Birgit Alber Costica Aloman Robert P. Anderson Asa Abeliovich Ariel Agmon Tom Alber Jose´ Alonso Timothy Anderson Birgit Abler Noe¨l Agne`s Mark Albers Carlos Alonso-Alvarez Inger Andersson Robert Abraham Vladimir Agranovich Matthew Albert Suzanne Alonzo Tommy Andersson Wickliffe Abraham Anurag Agrawal Kurt Albertine Carlos Alos-Ferrer Masami Ando Charles Abrams Arun Agrawal Susan Alberts Seth Alper Tadashi Andoh Peter Abrams Rajendra Agrawal Adriana Albini Margaret Altemus Jose Andrade, Jr.
    [Show full text]
  • Exploration of Causal and Correlational Modelling in Cancer : Glioblastoma Case Study
    EXPLORATION OF CAUSAL AND CORRELATIONAL MODELLING IN CANCER : GLIOBLASTOMA CASE STUDY by SOMPOP SAENGPHUENG Submitted in partial fulfillment of the requirements For the degree of Doctor of Philosophy Dissertation Advisor: Dr. Sree N. Sreenath Department of Electrical Engineering & Computer Science CASE WESTERN RESERVE UNIVERSITY May 2015 CASE WESTERN RESERVE UNIVERSITY SCHOOL OF GRADUATE STUDIES We hereby approve the dissertation of SOMPOP SAENGPHUENG candidate for the Doctor of Philosophy degree * Dr. Sree N. Sreenath Dissertation Advisor Professor, Dr. James W. Jacobberger Professor, Dr. Mihajlo Mesarovic Professor, Dr. Vira Chankong Associate Professor, Dr. Evren Cavusoglu Assistant Professor, July 8th, 2014 *We also certify that written approval has been obtained for any proprietary material contained therein. Table of Contents Table of Contents ............................. iii List of Tables ............................... vii List of Figures ............................... viii Acknowledgement ............................. x Abstract .................................. xi 1 Introduction 1 1.1 Objective and Challenge ......................... 1 1.2 Biological Problem ............................ 4 1.3 Hallmark of Cancer and Angiogenesis .................. 7 1.4 Cause and Correlation of Angiogenesis in Glioblastoma ........ 8 1.5 Computer-aid analysis of causal structure ................ 9 1.6 Glioblastoma ............................... 9 1.7 Summary ................................. 9 2 Background 11 2.1 Glioblastoma or Glioblastoma
    [Show full text]
  • Napoleone Ferrara Receives the 2010 Lasker~Debakey Clinical Award for Breakthroughs in Angiogenesis Research
    Napoleone Ferrara receives the 2010 Lasker~DeBakey Clinical Award for breakthroughs in angiogenesis research Ushma S. Neill J Clin Invest. 2010;120(10):3409-3412. https://doi.org/10.1172/JCI45092. News When Napoleone Ferrara was a medical student in Italy in the 1970s, he became interested in reproductive endocrinology. Although his training never specifically focused on angiogenesis, he is recognized today for shaping the field through the discovery of its core signaling molecule, VEGF, and for exploiting VEGF for the first successful clinical treatments of wet age-related macular degeneration (AMD) and cancer. On September 21, 2010, the Albert and Mary Lasker Foundation announced they will present Ferrara (Figure 1) with the 2010 Lasker~DeBakey Clinical Medical Research Award for his work on VEGF, which led to an effective therapy for neovascular AMD. Ferrara spoke with the JCI about his journey from discovery to treatment. Revving the endocrine engine Ferrara grew up in the shadow of the most active European volcano in Catania, Sicily. His father was a judge, and others in his family were in the legal profession, but his interest in the life sciences started even in high school: “To me,” Ferrara said, “it was much more interesting than the law.” He followed his passion to medical school, where he felt fortunate to land in the laboratory of Umberto Scapagnini. Ferrara noted that the University of Catania was much better known for its clinical focus than for its research, but “along came this dynamic young pharmacology professor who had trained for […] Find the latest version: https://jci.me/45092/pdf News Napoleone Ferrara receives the 2010 Lasker~DeBakey Clinical Award for breakthroughs in angiogenesis research When Napoleone Ferrara was a medi- knew best, and the endocrine cells that con- had the opportunity to go back to Italy, he cal student in Italy in the 1970s, he became trolled ovarian function were located in the said, “my heart wanted to stay in the United interested in reproductive endocrinology.
    [Show full text]
  • Acknowledgment of Reviewers, 2017
    Acknowledgment of Reviewers, 2017 The PNAS editors would like to thank all the individuals who dedicated their considerable time and expertise to the journal by serving as reviewers in 2017. Their generous contribution is deeply appreciated. A Katarzyna P. Adamala Hiroji Aiba Christine Alewine Jean Alric Hillie Aaldering Andrew Adamatzky Erez Lieberman Aiden Caroline M. Alexander Eben Alsberg Lauri A. Aaltonen Jozef Adamcik Allison E. Aiello R. Todd Alexander Manfred Alsheimer Duur K. Aanen Igor Adameyko Iannis Aifantis Alfredo Alexander-Katz Grégoire Altan-Bonnet Matthew L. Aardema Vic Adamowicz Christopher Aiken Anastassia N. Lee Altenberg Dirk G. A. L. Aarts David J. Adams Roger D. Aines Alexandrova Galit Alter Adam R. Abate David J. Adams Tracy D. Ainsworth Frank Alexis Orly Alter Cory Abate-Shen Jonathan Adams Edoardo Airoldi Emil Alexov Florian Altermatt Peter Abbamonte Michael E. Adams Jacqueline Michael Alfaro Marcus Altfeld Abul K. Abbas Patti Adank Aitkenhead-Peterson Hashim M. Al-Hashimi Dario C. Altieri Emmanuel A. Abbe R. Alison Adcock Slimane Ait-Si-Ali Asfar Ali Katye E. Altieri Shahal Abbo Zach N. Adelman Joanna Aizenberg Nageeb Ali Amnon Altman David H. Abbott Robert S. Adelstein Javier Aizpurua Robin R. Ali John D. Altman Geoffrey W. Abbott Andrew Adey Jaffer A. Ajani Saleem H. Ali Steven Altschuler Nicholas L. Abbott W. Neil Adger Caroline M. Ajo-Franklin Karen Alim Andrea Alu Omar Abdel-Wahab Jess F. Adkins Myles Akabas Michael T. Alkire Veronica A. Alvarez Ibrokhim Y. Ralph Adolphs Michael Akam Suvarna Alladi Javier Álvarez Abdurakhmonov Markus Aebi Omar S. Akbari Frédéric H.-T. Allain Arturo Alvarez-Buylla Ikuro Abe Yehuda Afek Erol Akcay David Alland David Amabilino Junichi Abe Hagit P.
    [Show full text]