Chapter 2 Test Review
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Unit III, Modules 9-13 Test Review • See also the Unit III notes and pages 76-122 • About 45 m.c., plus two essays; one on brain functioning, the other review concepts from previous units. • Some practice questions are embedded in this presentation • Other practice questions are available at the textbook website and in the textbook after each module. Neuron Order of a transmission: dendrite, cell body, axon, synapse (see arrow below) Neural Communication Neurons, 80 Neural Communication • (a)Dendrite – the bushy, branching extensions of a neuron that receive messages and conduct impulses toward the (b)cell body • (c)Axon – the extension of a neuron, ending in branching terminal fibers, through which messages are sent to other neurons or to muscles or glands • Myelin [MY-uh-lin] Sheath – a layer of fatty cells segmentally encasing the fibers of many neurons – makes possible vastly greater transmission speed of neutral impulses, – Damage to can lead to Multiple sclerosis Neural Communication • Action Potential – a neural impulse; a brief electrical charge that travels down an axon; DEPOLARIZED – generated by the movement of positively charges atoms in and out of channels in the axon’s membrane • Threshold – the level of stimulation required to trigger a neural impulse Action Potential A neural impulse. A brief electrical charge that travels down an axon and is generated by the movement of positively charged atoms in and out of channels in the axon’s membrane. Practice question • Multiple sclerosis is a disease that is most directly associated with the degeneration of: a. the myelin sheath. b. the pituitary gland. c. endorphins. d. dendrites. Myelin Sheath – a layer of fatty cells segmentally encasing the fibers of many neurons – makes possible vastly greater transmission speed of neutral impulses, – Damage to can lead to Multiple sclerosis Sensory neurons • 1. Shoulder receptors detected the squeeze • Sensory neurons carried the info to your spinal cord • Sensory Neurons carry incoming information from the sense receptors to the CNS. Sensory Neuron (Bipolar) Interneurons • carried the information to your brain • Interneurons in your brain interpreted the info: “Hey someone squeezed my shoulder!” • Interneurons connect the other two neurons Interneuron Neuron (Unipolar) Motor neurons • carried the command for your hand to squeeze the shoulder of the person in front of you. • Motor Neurons carry outgoing information from the CNS to muscles and glands. Motor Neuron (Multipolar) Kinds of neurons and their location • Interneurons – Central Nervous System (CNS) neurons that internally communicate and intervene between the sensory inputs and motor outputs • Motor Neurons in the peripheral nervous system – carry outgoing information from the CNS to muscles and glands – Skeletal Nervous System – the division of the peripheral nervous system that controls the body’s skeletal muscles Kinds of Neurons, 62 Sensory Neurons carry incoming information from the sense receptors to the CNS. Motor Neurons carry outgoing information from the CNS to muscles and glands. Interneurons connect the two neurons. Interneuron Neuron Sensory Neuron (Unipolar) (Bipolar) Motor Neuron (Multipolar) Refractory Period & Pumps, 56 Refractory Period: After a neuron fires an action potential it pauses for a short period to recharge itself to fire again. Sodium-Potassium Pumps: Sodium-potassium pumps pump positive ions out from the inside of the neuron, making them ready for another action potential. Threshold, 56 Threshold: Each neuron receives depolarizing and hyperpolarizing currents from many neurons. When the depolarizing current (positive ions) minus the hyperpolarizing current (negative ions) exceed minimum intensity (threshold) the neuron fires an action potential. Action Potential, 55 A neural impulse. A brief electrical charge that travels down an axon and is generated by the movement of positively charged atoms in and out of channels in the axon’s membrane. Action Potential Properties All-or-None Response: When the depolarizing current exceeds the threshold, a neuron will fire. If the depolarizing current fails to exceed the threshold, a neuron will not fire. Intensity of an action potential remains the same throughout the length of the axon. Parts of a Neuron Cell Body: Life support center of the neuron. Dendrites: Branching extensions at the cell body. Receive messages from other neurons. Axon: Long single extension of a neuron, covered with myelin [MY-uh-lin] sheath to insulate and speed up messages through neurons. Terminal Branches of axon: Branched endings of an axon that transmit messages to other neurons. Neurotransmitters: chemical messengers released into synapse Reuptake: Prozac effects prevention of for serotonin Neurotransmitters in the synapse are reabsorbed into the sending neurons through the process of reuptake. This process applies the brakes on neurotransmitter action. Antidepressant drugs and serotonin, Antidepressant drugs like Prozac, Zoloft, and Paxil are Selective Serotonin Reuptake Inhibitors (SSRIs) that improve the mood by elevating levels of serotonin by inhibiting reuptake Can lead to neurogenesis: new brain cells. Agonists (see 82) Botox as an antagonist, 83 A poison (botulin) is injected into the face to block the working of ACh and relaxing the facial muscles. Re-injections are needed. http://test.selfinnovations.com/sc/images/crowsBefore.gif Curare: an antagonist • Curare acts only at muscular synapses and NOT at the synapses of the central nervous system (curare does not cross the blood-brain barrier), • Thus, a victim of curare poisoning may be aware of what is happening until the very end. • The victim can feel the paralysis progressing but is quickly unable to move, call out or gesture. • If artificial respiration is performed throughout, the victim usually recovers without ill effects. How it affects the body • Death from curare is caused by paralysis of the respiratory muscles. • The alkaloid curare molecule mimics the neurotransmitter ACETYLCHOLINE by binding to its receptor at muscle synapses. ACTS AS AN ANTAGONIST. • This prevents nerves from stimulating muscle contraction. • Paralysis sets in gradually, because curare must compete for receptor binding sites before occupying them Practice question • Botox injections smooth facial wrinkles because botulin is a(n): a. ACh antagonist. b. dopamine antagonist. c. ACh agonist. d. dopamine agonist. Agonists and antagonists, 59 • These are NOT neurotransmitters • Agonists mimic (act like) the action of neurotransmitters • Example: nicotine mimics Ach • Antagonists block the action of neurotransmitters • Example: curare blocks Ach (leading to paralysis of muscles) Practice question • A drug that blocks the reuptake of a particular neurotransmitter is called a(n): a. opiate. b. antagonist. c. glutamate. d. agonist. Motor neurons (CNS) • carried the command for your hand to squeeze the shoulder of the person in front of you. • Motor Neurons carry outgoing information from the CNS (brain and spinal column) to muscles and glands. Motor Neuron (Multipolar) An Examination of the effect of autonomic nervous system on heart rate • One set of nerves, the sympathetic nervous system (SNS), is the fight or flight system, mobilizing your body. • Another set of nerves, the parasympathetic nervous system (PNS) works to slow down the body’s resources Parasympathetic Sympathetic • Like a symphony: gets you excited Practice question • The peripheral nervous system consists of: a. association areas. b. the spinal cord. c. the reticular formation. d. sensory and motor neurons. Interneurons • carried the information to your brain • Interneurons in your brain interpreted the info: “Hey someone squeezed my shoulder!” • Interneurons connect the other two neurons Interneuron Neuron (Unipolar) Reflex • a simple, automatic, inborn response to a sensory stimulus Brain Sensory neuron (incoming information) Interneuron Motor neuron (outgoing information) Muscle Spinal cord Skin receptors Hormonal System • Endocrine System – the body’s “slow” chemical communication system – a set of glands that secrete hormones into the bloodstream Pituitary Gland Is called the “master gland.” The anterior pituitary lobe releases hormones that regulate other glands. The posterior lobe regulates water and salt balance. Adrenal Glands, 91 Adrenal glands consist of the adrenal medulla and the cortex. The medulla secretes hormones (epinephrine and norepinephrine) during stressful and emotional situations, while the adrenal cortex regulates salt and carbohydrate metabolism. Electroencephalogram (EEG), 95 – an amplified recording of the waves of electrical activity that sweep across the brain’s surface AJ Photo/ Photo Researchers, Photo/Researchers, PhotoAJ Inc. – these waves are measured by electrodes placed on the scalp PET Scan, 68 PET (positron emission of National National Laboratories Courtesy Brookhaven tomography) Scan is a visual display of brain activity that detects a radioactive form of glucose while the brain performs a given task. MRI Scan, 68 MRI (magnetic resonance imaging) uses magnetic fields and radio waves to produce computer-generated images that distinguish among different types of brain tissue. Both photos from Daniel Weinberger, M.D., CBDB, NIMH Practice question • Which of the following would be most useful for detecting the brain areas that are most active as a person performs mathematical calculations? a. a brain lesion b. an fMRI c. a PET scan d. a hemispherectomy Corpus callosum Cerebral cortex