Meeting Program

XII European Meeting on Glial Cells in Health and Disease Bilbao | July 15 –18, 2015

Meeting Program

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2015

–18,

XII European Meeting XII European on Glial Cells in Health and Disease 15 Bilbao | July Meeting

GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 3 Program at a Glance �� 132 at a Glance Program Notes �� 130 Notes Map of Bilbao Public Transportation �� 128 Transportation Map of Bilbao Public �� 86 Session II Poster Session I�� Poster 44 Poster Sessions��Poster 42 �� 38 2015 18, July Saturday, �� 32 2015 17, July Friday, 2015�� 26 16, July Thursday, �� 21 2015 15, July Wednesday, �� 20 2015 14, July Tuesday, Schedule �� Schedule 20 General Information �� 16 Information General Surrounding Map �� 14 Map Surrounding Floor Plan �� 12 Floor Plan Exhibitors �� 10 Exhibitors Sponsors �� 9 Sponsors Local Organizing Institutions �� 8 Institutions Local Organizing Committees �� 7 Committees Acknowledgements �� 6 Acknowledgements Welcome �� 4 Welcome table of Contents table 4 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon Kettenmann forsetting thisup. like toparticularlythank ErikBoddeke,KrisJessen,MeinoGibson andHelmut Glia formedbytheprevious organizersoftheEuropeanGlialMeetings. Iwould organizers, K.I.T. Group,inassociation withthenon-profitorganizationNetwork The logisticsoftheMeetinghavebeenarranged bytheprofessionalcongress the cityhasbecomeaculturalreferencein SouthernEurope. combines traditionwithmodernity. Famousforitstapabarsandrestaurants, perienced atremendousmodernizationin recentyears.Itisalivelycitythat Bilbao istheeconomicalcapitalofBasqueCountry, acitythathasex- Old Quarter. within walkingdistancetomajorhotels,theGuggenheimMuseumand The EuskaldunaCentreisveryconvenientlylocatedattheheartofBilbaoand manently underconstructiononthesiteofformerEuskaldunaShipyard. one oftheflagshipsnewBilbao,whichwasdesignedasavesselper The GliaMeeting2015isbeingheldattheEuskaldunaConferenceCentre, with aninterestinglialcells. also becomprisedoftheyoungandgrowinglocalcommunityneuroscientists say,happy to participants, weare meeting. The sphere surroundingthis will record whichreflectsthegrowinginterestingliabiologyandvibrantatmo- is expectedtoreachnear1,200participantsfromabout45countries,anew The BilbaoMeetinghasreceivedover650posterabstractsandtheattendance grown insizetomorethan1,000participantsthelastmeetingBerlin. Glial MeetingshavebeenheldthroughoutEuropeeverysecondyearand sity ofHeidelbergwheremorethan600participantsgottogether. Subsequent series hasbecomeatraditionsincethefirstgatheringin1994atUniver comes toSpainaftertheoneheldinBarcelona2000.TheGlialMeeting This isthesecondtimethatthisimportantmeetingofglialcommunity 30 symposiareflectingthewiderangeoftopicsinglialfield. gram committeehasorganizedsevenexcellentplenarylecturesandselected pean MeetingonGlialCellFunctioninHealthandDiseaseBilbao.Thepro- On behalfofNetworkGliaandtheorganizers,IwelcomeyoualltoXIIEuro- Dear GliaCommunity, a w welcome M arM wElCo to all of you! all toME - - GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 5 - Carlos Matute Chair Local Organizing Committee We are very grateful for the generous support of Euskampus, the Basque Gov- are very grateful for the generous support We and IBRO Pan-European Center for Neuroscience, ernment, Achucarro Basque for providing stipends to support the par Regional Committee (IBRO-PERC) With your participation I am I hope that you will enjoy the meeting and our city. confident this meeting will be a grand success. ticipation of young scientists in the Introductory Course. I also acknowledge ticipation of young scientists for providing the abstracts as a USB drive as the support of Wiley-Blackwell providing stipends for young scientists, and the a supplement to GLIA and for for supporting several symposia, and all the Spanish Society of Neuroscience sponsors and exhibitors. 6 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon financial supportofthefollowingpartners(inalphabeticorder): Cells in Health andDisease gratefully acknowledge the collaboration and the The NetworkGliae.V. andtheorganizersofXIIEuropeanMeetingonGlial acknowledgements Committee (IBRO-PERC) IBRO Pan-EuropeanRegional Basque Government for Neuroscience Achucarro BasqueCenter Wiley-Blackwell University oftheBasqueCountry (SENC) Spanish SocietyforNeuroscience Ikerbasque GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 7

CoMMIttEE CoMMIttEE anIzInG CoMMIttEE orG raM anIzInG al Carlos Matute (Achucarro Center, Bilbao), Chair Carlos Matute (Achucarro Center, Alfonso Araque (Cajal Institute, Madrid) Bernardo Castellano (Universidad Autónoma, Barcelona) Fernando de Castro (Paraplegic Hospital, Toledo) Hugo Cabedo (Neuroscience Institute, Alicante) Bilbao) María Domercq (Achucarro Center, Luis Miguel García Segura (Cajal Institute, Madrid) Anna Planas (IDIBAPS, Barcelona) Bilbao) Jaime Sagarduy (Achucarro Center, Bilbao) Amanda Sierra (Achucarro Center, loC Anne Baron-Van Evercooren (France) Anne Baron-Van G. M. Boddeke (Netherlands) Hendrikus W. Bernardo Castellano (Spain) Christine Dijkstra (Netherlands) Kristjan Jessen (UK) Helmut Kettenmann (Germany), Chair Rebecca Matsas (Greece) Carlos Matute (Spain) Rhona Mirsky (UK) Eva Sykova (Czech Republic) orG Anne Baron-Van Evercooren (France), Chair Evercooren Anne Baron-Van (France) Etienne Audinat Sue Barnett (UK) Peter Brophy (UK) Philip Haydon (USA) Frank Heppner (Germany) Kristjan Jessen (UK) Helmut Kettenmann (Germany) Macklin (USA) Wendy Gianvito Martino (Italy) Rebecca Matsas (Greece) Carlos Matute (Spain) Klaus-Armin Nave (Germany) Hideyuki Okano (Japan) Sofroniew (USA) Michael V. (Germany) Jacqueline Trotter ProG Committees 8 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon Institutions local organizing (CSIC –SESCAM),Toledo Hospital NacionaldeParapléjicos (IDIBAPS), Barcelona mèdiques AugustPiiSunyer Institut d’InvestigacionsBio- Bilbao for Neuroscience Achucarro BasqueCenter (CSIC –UMHFISABIO), Alicante Instituto deNeurociencias Instituto Cajal(CSIC),Madrid Barcelona Institut deNeurociències(UAB), GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 9 or orS or orS SPonS al SPonS SPonS

loC BronzE SPonS GolD Sponsors support: for their sponsors the following like to thank would We 10 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon www.jireurope.com/home.asp jugates forFar-red andInfrareddetection onWestern blots. copy sample preparation,andsurgical microscopes. laser scanningmicroscopy withrelatedimagingsystems,electron micros- leaders incompound andstereomicroscopy, digitalmicroscopy,confocal for theiropticalprecision andinnovativetechnology. Itisone ofthemarket ness inthenineteenthcentury, itsinstruments have been widely recognized time. OurlatestproductsincludeAlexaFluor throughout Europeandincludesfirst-handtechnicaladviceinEuropean femtonics ltd. order, asatJune2015): We wouldliketothankthefollowingexhibitorsfortheir Exhibitors leica Microsystems Jackson Immunoresearch Europe ltd. www.femtonics.eu our unique modular systemsbuiltaccordingtocustomers’requirements. the researchers’pointofviewarenotonlyourreliabilityandfriendlypricesbut our microscopesarewidelyusedallaroundtheglobe.Ourmainstrengthsfrom suit otherapplications,includingbiophysicaluse.We canproudlystatethat ensuresthattheycan beeasily adapted to Furthermore, their modular nature search andpharmaceuticaldevelopment. 3D opticalmeasurementsandareespeciallysuitedforcutting-edgebrainre- investigations. Ourmicroscopesaretunedforthefastest,real-time2Dand scanning micro of laser

Femtonics focusesontheresearchanddevelopment of two-photonmicroscopy. Femtonics Ltd.isaR&Dcompany, operatinginthefield scopes for the booming area of(neuro)physiological booming scopes forthe Ever since the company started as a family busi- Ever sincethecompanystartedasa analysis ofmicrostructuresandnanostructures. microscopes andscientificinstruments forthe manufactures develops and Leica Microsystems

Our rapid,efficient,directserviceextends and Conjugates. supplies FirstClassSecondaryAntibodies ® 680 andAlexaFluor support (alphabetic ® Booth No. 4 Booth No. 5 Booth No. 2 790 con- GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 11 - - Booth No. 3 Booth No. 1

Thorlabs, a vertically integrated photonics prod- was founded in 1989 to serve ucts manufacturer,

Miltenyi Biotec is a global provider of products and ser Miltenyi Biotec is a global provider research and cellular vices that advance biomedical innovative tools support research at every Our therapy. translational research to level, from basic research to scientists and clinicians clinical application. Used by www.miltenyibiotec.com around the world, our technologies cover techniques of sample preparation, around the world, our technologies of ex- and cell culture. Our 25 years cytometry, cell isolation, cell sorting, flow - neuro stem cell biology, immunology, including pertise spans research areas Biotec has more than 1,400 employees in Miltenyi Today, science, and cancer. clinicians make a 25 countries – all dedicated to helping researchers and greater impact on science and health. tHorlaBS GmbH Miltenyi Biotec GmbH Miltenyi www.leica-microsystems.com Leica Microsystems has seven major plants and product development sites product development plants and seven major has Leica Microsystems has in over 100 countries, The company is represented around the world. network and an international organizations in 20 countries, sales and service Germany. are located in Wetzlar, partners. Its headquarters of distribution www.thorlabs.com the laser and electro-optics research market. As that market has spawned a the laser and electro-optics research market. As that market its core competen- multitude of technical innovations, Thorlabs has extended cies in an effort to play an ever increasing role serving the Photonics Industry medical, and de- at the research end, as well as the industrial, life science, highly integrated and diverse manufactur fense segments. The organization’s DFB, and VCSEL ing assets include semiconductor fabrication of Fabry-Perot, lasers, fiber towers for drawing glass optical fibers (silica, fluoride, tellurite, extensive glass and hollow core), MBE/MOCVD epitaxial wafer growth reactors, deposition capabilities, and metal fabrication facilities, advanced thin film and optomechanical and optoelectronic shops. 12 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon floor Plan street LeveL entrance 3: Main Access to the Meeting Art Exhibition LeveL -1 Media Check, Network Glia Office, Access to Auditorium

LeveL -2 Main Area: exhibition, session rooms, Posters

D2 Room D2 MEDIA CHECK D3 Room D3 NETWORK GLIA OFFICE

1 MEETING OFFICE 2 POSTER HELP DESK 3 Stairs between Level-2 and Level-1

Art Exhibition Exhibition Area Poster Area

Catering Area ENTRANCE 3 Main Access to the Meeting

GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 13

Main Access to the Meeting the to Access Main

Catering Area Catering ENTRANCE 3 ENTRANCE

floor Plan floor

Art Exhibition Art Exhibition Area Exhibition Poster Area Poster

3 l Leve between Stairs l Leve and -2 -1

2 POSTER HELP DESK HELP POSTER

1 MEETING OFFICE MEETING

D3 Room D3 NETWORK GLIA OFFICE GLIA NETWORK D3 Room

D2 Room D2 MEDIA CHECK MEDIA D2 Room Art Exhibition Art 14 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon Surrounding Map

BankS SHoPPInG rEStaurantS 16 restaurant Lúpulo 21 restaurant Yandiola Calle María Díaz de Haro, 7 Plaza Arrikibar, 4 1 Banco Popular 6 shopping Center Zubiarte 11 Foro Pizza 48013 Bilbao 48010 Bilbao Calle Ybarra Rafaela, 27 Calle Lehendakari Leizaola, 2 Botica Vieja, 27 48014 Bilbao 48001 Bilbao 48014 Bilbao 17 restaurant La Galea 22 restaurant La Florinda Calle de Rodríguez Arias, 71 Plaza Arrikibar, 4 2 Banco sabadell 7 supermarket Bm 12 McDonald's 48013 Bilbao 48010 Bilbao Gran Vía Don Diego López de Haro, 64 Calle Iruña, 9 Shopping Centre Zubiarte 48011 Bilbao 48014 Bilbao Calle Lehendakari Leizaola, 2 48001 Bilbao 18 Café estoril Plaza Emilio Campuzano, 3 3 Bnp Paribas 8 supermarket Carrefour 48011 Bilbao G Guggenheim Museum Gran Vía Don Diego López de Haro, 60 Calle María Díaz de Haro, 14 13 Cocktail Bar Jaime 48011 Bilbao 48013 Bilbao Gran Vía Diego López de Haro, 86 48009 Bilbao 19 restaurant el Huevo Frito Metro stops Calle del Maestro García River, 1 4 targobank 9 supermarket ercoreca 48011 Bilbao Calle de Rodríguez Arias, 65 Calle de Rodríguez Arias, 61 14 restaurant Le bol blanc tramway stops euskalduna 48013 Bilbao 48013 Bilbao Gran Vía Don Diego López de Haro, 87 and Arriaga 48911 Bilbao 20 Pizzeria La Foca Nicanora Calle de Iparraguirre, 3 5 Deutsche Bank 10 supermarket Carrefour 48009 Bilbao Plaza de Emilio Campuzano, 3 Calle Colón de Larreátegui, 40 15 restaurant Foster's Hollywood 48011 Bilbao 48009 Bilbao Gran Vía de Don Diego López de Haro, 68 48011 Bilbao

GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 15

Arriaga (Stop Old Town) Old (Stop Arriaga

22 21

4 8

3 10

Bizkaia Aretoa Bizkaia

Euskalduna

11 1 16 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon ElECtrICIty For thecorresponding certificates,pleaserefertothemeeting office. Attendance atbothIntroductoryCourseand meeting:1creditpoint Attendance perday: 1/5creditpoint Attendance attheIntroductoryCourse: Poster presentation: Students cancollectfollowingECTScredit pointsforattendingthemeeting: CrEDIt meeting hastakenplace. Certificates ofattendancewillbesenttoeveryparticipantbye-mailafterthe CErt about Bilbaoandsurroundings. information kind of interested participantswithany ference centre,providing During themeeting,atouristinformationdeskwillbeavailableatcon- BIlB “Public transportationandtravel”onpage18formoreinformation). the entiredurationofconference(startingfromTuesday untilSaturday, see The badgegivesalsodelegatesfreeaccesstothetramnetworkinBilbaofor badge visiblyatalltimes. which allowsentrancetothemeeting.Allparticipantsareaskedweartheir Upon registrationatthemeetingoffice,attendantswillreceiveanamebadge Ba –Glia Ceramic:collectionofpotterybasedonglialcells. Massana ArtSchoolbasedonNeuroscienceinspiration –Deconstructed neuroscience:collectionofjewelsmadebythestudents –Neurojewels: collectionofjewelsbasedonglialmorphologies –Glia inWatercolors –Pictures ofGlialCellsfrommemberstheSpanishNetwork –Cell onCanvas:collectionfromCarlosBarcia in followingsections: divided will be meeting. It displayed duringthewhole will be exhibition” art In additiontotheposterpresentationandindustrialexhibition,a“Glia art planner atthemeetingwebsite. registered participants).Additionallytheyareavailableviatheonlineitinerary available onsiteattheconferenceonaUSBmemorystick(freeofchargeforall The meetingabstractswillbepublishedinelectronicformatGLIAand a I General Information n alPHa BStra DGE EXHIBItI ao If IC I CtS PoI nforM at BEt ntS E of E IC orDEr on Su forStuDEnt at ly PPly att I on P EnD

oI anCE 1/5 creditpoint nt 1 creditpoint 230 V–50HzAC GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 17 - ICE 08:00–19:00 08:00–19:00 08:00–16:30 +49 176 83466704 [email protected] S’ SErv /SPEakEr on CCESS I M offICE/Cloakroo t a zat SESSIonS CHECk rnE anI uranCE EEtInG Each poster will hang for two days: Posters with poster number ending of an posters with poster numbers ending and Thursday, A will hang on Wednesday of a B will hang on Friday and Saturday. PoStEr M Group GmbH K.I.T. Münzgasse 2, 01067 Dresden, Germany E-mail: [email protected] www.kit-group.org CD ROM about 2 hours in advance of your talk, at the latest, or the day before. CD ROM about 2 hours in advance own laptop will not be possible. Please note that using your Opening times: July 15, 2015 Wednesday, July 16, 2015 Thursday, 08:00–20:30 Network Glia e. V. Max Delbrueck Center for Molecular Medicine (MDC) Berlin-Buch Robert-Rössle-Straße 10, 13092 Berlin, Germany E-mail: [email protected] www.networkglia.eu Friday, July 17, 2015 Friday, July 18, 2015 Saturday, Phone: E-Mail: orG MEDIa is located in the room D2 (see floor plan The media check for oral presentations / on a memory stick kindly ask you to hand in your presentation on page 12). We lunCH that on Please note from Thursday to Saturday. Lunch boxes will be served no lunch will be served. Wednesday Wireless internet access is available free of charge throughout the conference of charge throughout the conference access is available free Wireless internet venue. GLIA Network Login: Password: Bilbao15 IntE sonal insurance. Participants are advised to carry out their own insurance own insurance out their advised to carry are Participants sonal insurance. policies. The organizers do not take responsibility for individual medical, travel or per medical, for individual take responsibility do not The organizers InS 18 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon Posters withnumbersendingA: uneven serialnumbers.Eachposterispresentedintwosessionsof60min. poster duringthesession.Thesessionsaredividedintoevenand The presentingauthorofeachposterisrequestedtobepresentather/his a taxistandoutsideof thearrivalhallatBilbaoAirport. Taxis generally takeabout20–25minutesandcost upto€30perride.Thereis Via 79”. Costforasingleticket:€1.45 city. TheneareststoptotheEuskaldunaConferenceCentreis“Gran The busrunsthroughoutthedayandtakes about20 shuttle busBizkaibusA3247.Thestopislocated justoutsideofthearrivalhall. from thecentreofBilbaofromairportistotake cheap waytogetand The Bilbaoairportislocatedabout12kmawayfromthecity. Asimpleand How toreachthecitycenter/venuefromBilbaoairport PuBl poster helpdesk. Appropriate adhesivematerialtohangyourposterwillbeavailableatthe The sizeofaposterisDINA0landscapeformat(85 session. All postersmustberemovedonSaturday, July –Even serialnumbers(e.g.T03-04B) Saturday, July18,2015 Friday, July17,2015 –Uneven serialnumbers(e.g.T03-03B) Saturday, July18,2015 Friday, July17,2015 (Hanging ofposters:Thursday, July16,from17:00 / Posters withnumbersendingB: All postersmustberemovedonThursday, July16until16:00. –Even serialnumbers(e.g.T03-04A) Thursday, July16,2015 Wednesday, July15,2015 17:15–18:15and –Uneven serialnumbers(e.g.T03-03A) Thursday, July16,2015 Wednesday, July15,2015 (Hanging ofposters:Wednesday, July15,before10:00) IC tranSPortat I on Friday, July17,before10:00) anD travEl 14:00–15:00 14:15–15:15 and 13:00–14:00 13:15–14:15 and 14:15–15:15 18:15–19:15 and 13:15–14:15 18 directlyaftertheposter cm height,119width). minutes togetintothe GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 19 (Scientists) / €65.00 / (Students) Tel. +34 94 444 88 88 Tel. +34 94 410 21 21 Tel. €170 €230 €550 €595 ourSE C tory on XI nuE IntroDuC nuE I EGIStrat egistration includes fee Conference bag including program booklet, abstract USB stick, city map and sponsor materials (located in walking distance to the Euskalduna Conference Centre) vE The Euskalduna Conference Centre and Concert Hall Abandoibarra, 4, 48011 Bilbao Avenida www.euskalduna.net Radio Teletaxi, Radio Teletaxi, vE ta including airportThe following taxi companies offer a 24-hour service in Bilbao, transfers: Bilbao, Radio Taxi –Admission to all sessions, poster area and exhibition –Lunch boxes from Thursday to Saturday evening Informal get-together with free drinks on Wednesday – – Saturday to –Free access to all trams in Bilbao from Tuesday BIZKAIA ARETOA (Auditorium Mitxelena) Abandoibarra, 3, 48009 Bilbao Avenida registration per day: Scientists: r Students, PhD Students: Commercials: Students must show their valid student card! €120 Free access to the tram network of Bilbao: network to the tram Free access will have participants July 18 all registered 14 to Saturday, July From Tuesday, Students, PhD Students: Commercials: Biology: Introductory Course on Glial €30.00 €350 Full registration (all days): Scientists: r available on all conference days, registration fees On-site registration will be Mastercard or American Express. can be paid in cash or by VISA, free and unlimited tram access within the city. Please make sure to wear your sure to wear make Please city. the access within unlimited tram free and operated by the tram. The tram is badge while entering Euskalduna and connects the the company Euskotren and easily. with the old town quickly Conference Centre Please note that to take the free want is only valid for you access the tram. If ticket. bus, you have to buy a transport the metro or the 20 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon 09:45–10:30 09:00 09:00 Venue: 09:00–17:45 tu Scientific Program 11:15 10:30–11:15 14:15–15:00 13:15–14:15 12:30–13:15 11:45–12:30 17:00–17:45 16:15–17:00 -16:15 15:45 15:00–15:45 ESD – CarlosMatute Bilbao,Spain – 11:45

09:45 ay, July 14, 2015

elenaAlberdi Bilbao,Spain richardM.ransohoff Cambridge,USA JuanManuelencinas Bilbao,Spain

AlfonsoAraque Minneapolis,USA MarcoPrinz Freiburg, Germany AshwinWoodhoo Derio,Spain Brahim Nait-Oumesmar Paris,France

Charlesffrench-Constant Edinburgh,UK FrankKirchhoff Homburg,Germany Astrocytes –anintroduction Welcome Avenida Abandoibarra,3,48009Bilbao (Auditorium Mitxelena) BIZKAIA ARETOA Glia inAlzheimer’s disease Oligodendrocytes Introductory Course Coffee Break lunch Break Gliogenesis s astrocytes inneurotransmission Advances andchallengesinstudyingtheroleof Microglia intheuniverse ofmyleoidcellsintheCNs Microglia: areintroduction Coffee Break e chwann cells xperimental modelsofmyelinationandremyelination

supportedby

GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 21 O stUDY IOLOGICAL AND IOLOGICAL AND

NAs in microglia of NAs in microglia of HOP OF GLIA. OF GLIA. ION OF PHYs t IONs Cs to study the function of Cs to study the function of UALIZA GLIAL WOrKs re: MODerN teCHNIQUes t OPe tU Manchester, UK Alexej verkhratsky Manchester, IOLOGICAL FUNCt LL CUL ION AND vIs t OGLIA 2015 15, July , JAPANese-eUr HOPHYs YOND Ce t tudying the role of dicer and micror Yamanashi, Japan Organizers: schuichi Koizumi Yamanashi, Organizer: Knut Biber Freiburg, Germany ay PA tHe workshop II workshop MANIPULA Neurons and glia on the edge of cortical spreading Neurons and glia on the edge of cortical spreading depression Improvement of classical methods and development of of Improvement of classical methods and development of high throughput automated methods for the analysis glial morphology Imaging neuron microglia interaction in the hippocampus Imaging neuron microglia interaction in the hippocampus of awake mice In vivo imaging of microglia in the brain and spinal cord in in In vivo imaging of microglia in the brain and spinal cord health and disease s the developing and adult brain workshop I workshop MICr and bioinformatics Acute isolation of microglia s Preparation of chimeric OH workshops ramified microglia erlend A. Nagelhus Oslo, Norway Annette Masuch Freiburg, Germany erik Boddeke Groningen, Netherlands

Frederick rohan Walker Newcastle, Australia Martin Fuhrmann Bonn, Germany steffen Jung Rehovot, Israel Dimitrios Davalos San Francisco, USA ESD 13:00 – EDn Room A1 09:00–09:40 09:00 12:20–13:00 11:40–12:20 11:00–11:40 10:20–11:00 Sala Barria Be 09:00–09:40 09:00–13:00 09:40–10:20 09:00–13:00 w 22 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon 09:40–10:20 s 15:15–17:15 s 12:20–13:00 11:00–11:40 10:20–11:00 Auditorium s 14:15–15:15 Auditorium 14:00–14:15 13:00–14:00 11:40–12:20 Auditorium 01-01 01-02 01-03 MakiHoshiko Osaka,Japan valentinNägerl Bordeaux,France rebeccaLowery Rochester, USA Chair:ChristineDijkstra Amsterdam,Netherlands

KazuhiroIkenaka Okazaki,Aichi,Japan

ClaudiaKarus Düsseldorf, Germany MasamitsuIino Tokyo, Japan Kenjitanaka Tokyo, Japan

Dmitrirusakov London,UK CNs Fractalkinomics: onekeytotheplaceofmicrogliain richard M.ransohoff Cambridge,USA somatosensory cortex Development ofmicrogliainthemouseprimary ultrasensitive Ca physiology Imaging ofastrocytesodiumdynamicsin (patho-) Understanding calcium-drivenphysiologyofastroglia D Symposia I MICr Symposium S01 their engagementwith dendriticspines increases themotilityofmicroglialprocesses andimpacts t probe expressioninglialcells Ke opening Break In vivoimagingofglialCa How doesanoligodendrocyteselectaxonstomyelinate? A rolefor microglia insynaptic plasticity Plenary lectureP-01 Organizer: shigeoOkabe Tokyo, Japan he inductionofhippocampallong-term potentiation eveLOPMeNt NGe firmament OGLIA-Me -tet system:promisingstrategytoachievesufficient DIAteD CONtrOLOFPOstNA 2+ indicator 2+ dynamicsusingan t AL Br AIN GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 23 Y ON CNs IGNALLING AND IGNALLING AND ONAL ACtIvIt OLUMe s v OF NeUr MIssION, NCe AsIs st vladimir Parpura Birmingham, USA ragnhildur Karadottir Cambridge, UK in vivo ION ING INFLUe t t LINA ole of astrocytes in volume and water homeostasis LUCIDA strOCYte GLIOtrANs he effects of pharmacogenetic manipulation of neuronal manipulation of neuronal he effects of pharmacogenetic Organizers: robert Zorec Ljubljana, Slovenia Organizers: David Lyons Edinburgh, UK Organizers: David Imaging microglia and synapses with an optical clearing clearing with an optical synapses microglia and Imaging technique S02 Symposium e MYe r Astrocytic gliotransmitter vesicles and their interaction Astrocytic gliotransmitter vesicles and their interaction with the plasmalemma Lactate transport and signaling in the brain: potential therapeutic targets and roles in body-brain interaction Metabolic regulation of vesicular glutamate release from Metabolic regulation of vesicular glutamate release from cultured astrocytes WAter HOMeO Symposium S03 A Neuronal activity regulates remyelination via glutamate Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors Neuronal activity promotes oligodendrogenesis and oligodendrogenesis and Neuronal activity promotes mammalian brain adaptive myelination in the t in activity on oligodendrocyte turnover and myelination the developing mouse brain Using zebrafish to study how neuronal activity regulatesUsing zebrafish to study how myelination Ole Petter Ottersen Oslo, Norway Linda Hildegard Bergersen Oslo, Norway robert Zorec Ljubljana, Slovenia ragnhildur Karadottir Cambridge, UK vladimir Parpura Birmingham, USA stan Mitew Melbourne, Australia Stanford, USA Michelle Monje David Lyons Edinburgh, UK Tokyo, Japan Tokyo, shigeo Okabe 03-03 03-04 03-02 03-01 02-03 02-04 02-02 01-04 02-01 Sala Barria

s s s s

Room A1 s s s s s 24 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon s Room A4 s s s s Room A3 s 17:15–19:15 s s Exhibition Area 19:15–20:15 Poster Area 04-01 04-02 04-04 04-03 05-01 05-02 05-04 05-03 shaneLiddelow Stanford,USA HaukeWerner Göttingen,Germany AuroraPujol Barcelona,Spain stefanoPrevitali Milan,Italy LukeLairson LaJolla,USA LauraFeltri Buffalo,USA DiesMeijer Edinburgh,UK AlisonLloyd London,UK

s Symposium S04 and dysmyelinatingneuropathy Nuclear controlofaxonalsortinginnervedevelopment N new moleculesinvolvedinmyelination s role ofLGIproteins t Directing axonalregrowthfollowingnerveinjury sY Symposium S05 What doreactiveastrocytesdo? Proteomic approachtomyelin-relatedneuropathology r cascades inadrenoleukodystrophy Integrative –omicsanalysesuncoversinflammatorylipid Poster Session I Informal Get-togetherwithfree drink Organizers: stefanoPrevitali Milan,Italy Organizers: AuroraPujol Barcelona,Spain he functionalorganizationofmyelinatedaxonsandthe CHWANN Ce patial mappingofpolarizedaxo-glialinteractionsreveals erve D emyelination: drugdiscoveryandpharmacology steMA eveLOPMeNt t IC APPr Laura Feltri Buffalo,USA Hauke Werner Göttingen,Germany LL-AXON INterACt t OACHes ANDDIseA O GLIA ION CONtrOLs se P AL erIPHerAL Choose GLIA for your research Edited by Bruce R. Ransom and Helmut Kettenmann

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Reaching a Multidisciplinary Audience of Dedicated Biomedical Researchers. GLIA, the journal that launched the field of glial research, is still the journal of choice for neuroscientists, neurobiologists, neurologists, cell and developmental biologists, anatomists, pathologists, and neurochemists, looking for the most comprehensive coverage in this field of study. Impact Securing Rapid Online Publication through Factor: EarlyView® . Your article will be posted online as soon as it is ready, before the release of the compiled 4.82 print issue. Scan for Accessing a State-of-the-Art Submission GLIA news, System. GLIA offers online manuscript submission virtual issues, and peer-review via ScholarOne Manuscripts (fomerly top articles, known as Manuscript Central), a user-friendly system and more making manuscript submission and tracking quick, easy, and safe.

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Joining into an Intellectual Partnership with Wiley. Publishing at Wiley is truly a collaborative Facebook.com/gliajournal process. We value the long-term relationships we have with our authors and we are committed to maintaining the standard of excellence that has been essential to Wiley’s success for nearly two centuries. www.wileyonlinelibrary.com/journal/glia 26 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon s s s Room A1 s s s s s Auditorium 10:15-12:15 09:00–10:00 Auditorium tHurSD 07-01 06-02 06-01 06-04 06-03 07-04 07-03 07-02 CatherineLubetzki Paris,France t t BernardZalc Paris, France DavidHume Midlothian,UK MarcoPrinz Freiburg, Germany Fabiorossi Vancouver, Canada DiegoGomez-Nicola Southampton,UK Chair:ÉtienneAudinat Paris,France

ay, July 16, 2015 Microglia intheuniverseofmyeloidcellsCNs t OLIGODe Symposium S07 Microglial proliferationinchronicneurodegeneration Microglia polarization:mythsandrealities progenitor cellsintheadultCNs Demyelination-induced changesinoligodendrocyte AND PA and remyelination t differentiation andmyelination mtOr Wrapped uptight:netrinfunctioninmature myelin Symposia II MICr Symposium S06 plasticity Contribution ofastrocytestosynaptictransmissionand stéphane H.r.Oliet Bordeaux,France Plenary lectureP-02 Organizer: teresa Wood Newark,USA Organizers: DiegoGomez-Nicola Southampton,UK eresa Wood Newark,USA imothy Kennedy Montreal,Canada ransgenic Xenopus: a modelofinducibledemyelination he originsofmicroglia OGLIAL DYNAMICs signalinginoligodendrocyteprogenitor cell t HOLOGY NDr Marco Prinz Freiburg,Germany OCYte DIFFereNt INtHe H IA e AL t eNt ION INDeveLOPMeNt t HY ANDDIseA seD Br AIN GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 27 AND AND ses LIN DeveLOPMeNt re DIseA chwann cells after nerve injury IN rA LING IN MYe ION LLs erAt Hugo Cabedo San Juan de Alicante, Spain Pavia, Italy Daniela rossi IN reMODe clerosis t s reGeN OF GLIAL Ce OMA erve OLe chwann cell repair phenotype he role of class II HDACs in the transition towards the he role of class II HDACs in the transition towards the he role of chromatin remodeling in myelinating glia Organizers: Claire Jacob Fribourg, Switzerland Bezzi Lausanne, Switzerland Organizers: Paola t s Control of myelinating cell plasticity by chromatin- remodeling enzymes Chromatin dynamics in s Functional deficits of the astrocytes in Amyotrophic astrocytes in Amyotrophic Functional deficits of the Lateral Symposium S09 CHr N t Glial cell toxicity towards motor neurons in ALs Glial cell toxicity towards motor Symposium of International Society of Neurochemistry Symposium of International Astrocytes may be behind the pathogenesis of 22q11.Ds Astrocytes may be behind r Symposium S08 S08 Symposium Astrocyte dysfunctions in Huntington’s disease model mice disease model mice Astrocyte dysfunctions in Huntington’s Hugo Cabedo San Juan de Alicante, Spain Pavia, Italy Daniela rossi Claire Jacob Fribourg, Switzerland John svaren Madison, USA Brian Kaspar Columbus, USA Bezzi Lausanne, Switzerland Paola Michael Wegner Erlangen, Germany Los Angeles, USA Baljit Khakh 09-04 09-03 09-01 09-02 08-04 08-03 08-02 08-01 s s

Room A4 s s s s

Sala Barria s s 28 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon s s Room A3 s s Auditorium 15:15-17:15 Poster Area 13:15-15:15 12:15-13:15 s s s s 10-02 10-01 10-03 10-04 11-02 11-01 11-03 11-04 AlainBessis Paris,France Amandasierra Bilbao,Spain Wen-BiaoGan NewYork, USA Marie-Ève tremblay Québec, Canada JavierPalazuelos StonyBrook,USA Carolschuurmans Calgary, Canada IsmaelGalve-roperh Madrid,Spain BenediktBerninger Mainz,Germany

development andregeneration Ismael Galve-roperh Madrid,Spain Benedikt Berninger Mainz,Germany Organizers: Me A rolefort D Symposium S10 in neocorticaldevelopmentandgliomagenesis t to intermediateprogenitorcellsviamtOr t COMMUNICA Poster SessionI lunch Break NeUr Symposium S11 Symposia III From expandingtoreprogrammingNG2glia Microglial regulationofsynapticfunction apoptosis uncoupling Neuronal hyperactivitytriggersmicroglial phagocytosis- In vivostudiesofmicroglialfunctionin synapse formation contexts of neuroinflammation s Organizer: Marie-Èvetremblay Québec, Canada he roleofrAs- he endocannabinoidsystemcontrolsradialgliatransition tructural interactions betweenmicrogliaandsynapsesin eveLOPMeNt CHANIsMs ONs ANDMICr ACe t INGLIOGeN ION INHe AL /ADAM17 duringoligodendrocyte erK signalinginspecifyingglialcellfates s IGNALING OGLIA: BIDIreCt AL t esIs H ANDDIseA

IONAL ses supportedby C1 signalling

GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 29 ION t LINA ystem cells directly promote myelin regeneration in regeneration in cells directly promote myelin Edinburgh, UK veronique Miron t Federation e Y AND reMY egulatory patiotemporal calcium dynamics in single astrocytes and and patiotemporal calcium dynamics in single astrocytes nhancement of the activity of M2-polarized of M2-polarized nhancement of the activity Calgary, Canada Calgary, . Wee Yong odd Fiacco Riverside, USA PArADIGM sHIFt IN AstrOCYte CALCIUM sIGNALLING Cambridge, UK Cambridge, robin Franklin Organizers: s its modulation by neuronal activity Fundamental differences between spontaneous vs. low- level evoked astrocyte calcium activity disease Glial calcium dysregulation in Alzheimer’s Symposium S13 Alexey semyanov Nizhny Novgorod, Russian Organizer: Macroscopic and microscopic calcium dynamics of astrocytes e recovery from macrophages/microglia promotes demyelination r the Central Nervous s Macrophage activation in perinatal white matter injury Macrophage activation in perinatal Ageing macrophages and failing remyelination Ageing macrophages Symposium S12 Symposium t IMMUNI

Nizhny Novgorod, Russian Federation Alexey semyanov Armando Genazzani Novara, Italy t v Japan Yuji Ikegaya Tokyo, Denise Fitzgerald Belfast, UK Edinburgh, UK veronique Miron Cambridge, UK robin Franklin 13-03 13-04 13-02 13-01 12-04 12-03 12-02 12-01 s s s Room A3 s s s s Room A1 s 30 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon s A4 Room

s Barria Sala s s s

Auditorium 17:30-18:30 s s s 14-01 15-01 14-04 14-03 14-02 15-04 15-03 15-02 BozenaKaminska Warsaw, Poland Barteggen Groningen,Netherlands staciBilbo Durham,USA WendyCampana La Jolla,USA Jonathan Kipnis Charlottesville, USA GabrielCorfas Boston, USA AhmetHoke Baltimore,USA rudolfMartini Würzburg,Germany

Chair:AnneBaron-van evercooren Paris,France

Intrinsic andextrinsic regulationofCNs Charles ffrench-Constant Edinburgh, UK treatment ofinheritedneuropathies macrophages inmyelinmutants:implicationsfor s neuropathies: Challenges indevelopingnoveltherapiesforperipheral small moleculeGFr t neuroinflammation, regenerationandneuropathicpain r Symposium S14 DIseA e Symposium S15 pathologies e Plenary lectureP-03 Microglia phagocyticactivityandautism term neuralfunction Microglia andthedevelopingbrain:implicationsforlong- response e Organizer: WendyCampana LaJolla,USA tHe rOLeOFGLIALCeLLsINPerIPHerALNeUrOPAtHY Organizers: BozenaKaminska Warsaw, Poland reating smallfiberneuropathybytopicalapplicationof a chwann cellreactionsandmutualinteractionswith PIGeN pigenetic controlofmicrogliapolarizationinbrain pigenetic regulationofthemicrogliainflammatory egulation ofs se s s etICs Jonathan Kipnis Charlottesville,USA t HAPes GLIALFUNCt chwann cellphysiologybyLr argeting Glia α / ret modulator IONs INHe myelination P1: rolein AL t H AND IkErBaSquE

Ikerbasque, the Basque Foundation for Science, is the institution dedicated to fostering the production, promotion and dissemination of scientific knowledge in the Basque Country.

Among other activities, Ikerbasque currently runs different programmes to attract and retain talented researchers, in different career stages, and in all the fields of knowledge. Recruited scientists are appointed to the different Basque research institutions including universities, fundamental research centres, cooperative research centres and technology centres.

International senior and postdoctoral researchers willing to join the Achu- carro centre or other neuroscience related institutions in the Basque Coun- try are welcome to apply for any of our open calls.

For more information: www.ikerbasque.net

BIzkaIa talEnt

Bizkaia Talent is the agency supported by the Government of Bizkaia (estab- lished in 2005) with the mission of strengthening the conditions for attract- ing, connecting and retaining talented professionals in the Basque territory of Biscay (Bizkaia).

Bizkaia Talent seeks to promote and improve the most important factor in the development of any region: human resources. In so doing, it takes action to attract talent with the help of the leading companies and universities in the Basque Country.

Bizkaia Talent offers essential services for professionals and their families willing to start a careerand life in the Basque Country, from support in hous- ing and education, to leisure and personal and professional networking.

Join the network of professionals of Bizkaia Talent: Be Basque Network, be- cause you can also be Basque!

For more information: www.bizkaiatalent.org | www.bebasquetalentnetwork.org 32 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon s A1 Room s s s s s

Sala Barria 10:15-12:15 Auditorium 09:00-10:00 fr 17-01 16-04 16-03 16-02 16-01 17-02 ID Benemery Portland,USA CarlosParras Paris, France BeatrizAlmolda Barcelona,Spain t Michalschwartz Rehovot,Israel MonicaCarson Riverside,USA ay, July 17, 2015

Chair:HelmutKettenmann Berlin,Germany

DUr neuroinflammation viathebrain’s choroidplexus Fighting Alzheimer’s diseaseandbrainaging trANsCr Symposium S17 antigen-presenting cells epilepsy dependentonCNs t Microglia asregulatorsoft antigen presentingmechanismsassociatedtoeAe r regulation ofOPCgenesviainduction keymicro-r positive regulationofmyelingenesand negative Myrf promotesoligodendrocytematuration boththrough WIt tHe r Symposia Iv Symposium S16 Glial glycogen:asweetandsourstoryfullofsurprises Bruce r.ransom Seattle,USA Plenary lectureP-04 during (re)myelination Chd7 chromatinremodeler functioninoligodendrogenesis Organizers: CarlosParras Paris,France Organizers: BeatrizAlmolda Barcelona,Spain revor Owens Odense,Denmark celltargetedattackonastrocytestriggersprogressive ole ofmicroglia,macrophagesanddendriticcellsinthe OLe CONtrOLOFt HIN ING MYe OFMICr tHe IPt CNs Ben emery Portland,USA Monica Carson Riverside,USA IONAL reGULA IONAL LINA OGLIAL Ce t ION ANDreMYe -Ce LL resPONses LL LLs t influxofblood-derived ION OFOLIGODe IN IN cellresponseintheCNs

LINA

t ION supportedby NDr OGeN Is esIs NAs

GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 33 N AND N AND AIN ONAL ONAL - r B ON NeUr IN tHe NDYMO-GLIAL CeLL cf4 in oligodendrocyte cf4 in oligodendrocyte IONs AMMING BY OXYGe : IMPACt s OGr cf7l2/t OUs ePe HWAY t PA 4 expression in astrocytes by both 4 expression in astrocytes by both H DIverse FUNCt NDeNt etABOLIC rePr etABOLIC Coventry, UK Nicholas Dale Coventry, Luc Pellerin Lausanne, Switzerland ION WIt t AL ePe erGY-D rvIv egulation of MCt strOCYte M he transcription regulator t he transcription ANYCYtes - A HeterOGeNe Organizers: Mohammad K. Hajihosseini Norwich, UK Organizers: Juan P. Bolanos Salamanca, Spain Organizers: Juan P. Astrocyte-Neuron (mis)interactions in Huntington’s Astrocyte-Neuron (mis)interactions in Huntington’s disease Symposium S19 t Identity and genetic regulation of neurogenic tanycytes in Identity and genetic regulation of neurogenic tanycytes in the hypothalamus POPULA Importance of AMPK for the regulation of astrocyte energy Importance of AMPK for the regulation of astrocyte energy and amino acid homeostasis IGF-1 stimulates cell proliferation in a specific area of the of the IGF-1 stimulates cell proliferation in a specific area hypothalamic wall r oxygen tension and nitric oxide through a HIF-1α dependent mechanism t Symposium S18 A eN sU development and remyelination development Astrocytic NMDA receptors sustains antioxidant protection sustains antioxidant protection Astrocytic NMDA receptors Cdk5-Nrf2 pathway of neurons through a novel Daam2-PIP5K is a novel regulatory pathway for Wnt for Wnt is a novel regulatory pathway Daam2-PIP5K therapeutic target for remyelination signaling and Chile A. Castro Valdivia, Maite Helle Waagepetersen Copenhagen, Denmark Mohammad K. Hajihosseini Norwich, UK Luc Pellerin Lausanne, Switzerland Margarita Perez-Martin Malaga, Spain Bolanos Salamanca, Spain Juan P. Cincinnati, USA richard Lu Deneen Houston, USA Benjamin 18-04 19-02 19-01 18-03 18-02 18-01 17-04 17-03 Room A4

s s s s

Room A3 s s s s 34 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon s s s s s Auditorium s Poster Area 13:15-15:15 12:15-13:15 19-03 19-04 20-02 20-01 20-03 20-04 vincentPrévot Lille,France NicholasDale Coventry, UK Anne-MarievanDam Amsterdam,Netherlands BenteFinsen Odense,Denmark AriBarzilai Tel Aviv, Israel DanFrenkel Tel Aviv, Israel

t Parkinson’s disease e Alzheimer’s-like diseaseinmice Microglial DIseA hypothalamus t eAr Symposium S20 dynamics ofculturedcerebellarnetworks t Poster SessionII lunch Break cerebrovascular amyloiddepositioninAlzheimer’s disease affect astrocyte-endothelialinteractionsandtrigger Pathological changesinastrocytet Organizers: Anne-MarievanDam Amsterdam,Netherlands anycytes: thehypothalamichyperdriveforhormones anycyte nutrientsensingandcommunicationinthe he roleofastrocytealterationsinearlychangesthe arly microglialactivationbeyondthesubstantianigrain LY GLIALCe ses t NF andIL-1asearlydisease-modifiersin Dan Frenkel Tel Aviv, Israel LL CHANGesINBr AIN DeGeN GFbeta1 levels erAtI ve

GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 35

ING ING t LINA clerosis clerosis ION t MYe LINA supported by

CHANGes IN CNs ION AND reMYe t in the regulation of age-related in the regulation of age-related OGLIAL OGLIAL LINA GFβ LLULAr t MYe Kleopas Kleopa Nicosia, Cyprus Barcelona, Spain Bernardo Castellano AND Ce ING De XUs r strOCYte-MIC CULAr eAe A LL Ne egulation of synaptic connectivity of oligodendrocyte egulation of synaptic connectivity of oligodendrocyte he functional impact of astrocyte-microglial cell cell he functional impact of astrocyte-microglial Organizers: Domna Karagogeos Heraklion, Greece Sydney, Australia Campbell Sydney, Organizers: Iain Junctions and gaps: glial connexins in Multiple s and precursor cells in myelination and myelin repair r Promoting recovery after premature brain injury: a role Promoting recovery after premature brain injury: a role for enhanced epidermal growth factor receptor signaling Deconstructing and reconstructing the perinodal area in in Deconstructing and reconstructing the perinodal area demyelination and remyelination Symposia v Symposia S21 Symposium Symposium S22 MOLe GLIA DUr Astrocyte targeted production of either IL-6 and IL-10 Astrocyte targeted production of either IL-6 and IL-10 a promotes alterations in microglial activation and has direct effect on neuronal survival after peripheral nerve axotomy Astrocyte-derived astroglial and microglial Achieving specificity in the cytokines response to IL-6/gp130 family Ce t and amyloid pathology activation on synaptic function changes in microglia and neurodegeneration tHe

Kleopas Kleopa Nicosia, Cyprus Maria Cecilia Angulo Paris, France USA Joseph scafidi Washington, Heraklion, Greece Domna Karagogeos Bernardo Castellano Barcelona, Spain Australia Iain Campbell Sydney, Santiago, Chile rommy von Bernhardi Montgomery Marina Lynch Dublin, Ireland 22-04 22-03 22-02 21-04 22-01 21-02 21-03 21-01 s s s Auditorium 15:15-17:15

Room A1 s s s s

s 36 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon s

s s Room A3 s s Room A4 s s s 23-01 23-03 23-02 24-02 24-01 23-04 24-03 24-04 LuciaNotterpek Gainesville,USA ChristianGiaume Paris,France LawrenceWrabetz Buffalo,USA AlessandraBolino Milan,Italy ChristianLohr Hamburg,Germany MarijkeDeBock Ghent,Belgium Michaelsereda Göttingen,Germany Arantxatabernero Salamanca, Spain FUNCt A Connexin andCa and roleinneurovascularcoupling Calcium wavesinolfactoryensheathingcells:mechanism INv in amousemodelofAlzheimer’s disease Astroglial hemichannelscontributetoneuronalsuffering INterACt Symposium S23 neuropathies Protein qualitycontrolpathwaysinPMP22-linked s Symposium S24 Connexin43 ands permeability changesinvivo is implicatedininflammation-inducedblood-brainbarrier e trafficking andCharcot-Marie-t Phospholipid metabolism,theregulationofmembrane with solubleNeuregulin-1 e Organizers: ChristianGiaume Paris,France Organizers: AlessandraBolino Milan,Italy strOGLIAL CONNe CHWANN Ce ndoplasmic reticulumstressandhereditaryneuropathies xperimental therapyofCharcot-Marie-t OL v IONs ING NeUr IONs ANDPA Arantxa tabernero Salamanca, Spain Michael W. sereda Göttingen,Germany LL BIOLOGYOFCMt O-GLIO-vAs 2+ rc interactioningliomastemcells signalinginglialandendothelialcells t XINs HOLOGIes INBr r CULAr

AIN ooth neuropathies N eUr

OPA supportedby ooth disease1A t HIes

GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 37 tYAMMABILI OGr PrY AND re Munich, Germany sergio Gascon Pennsylvania University Park, USA University Pennsylvania Gong Chen Organizers: Plenary lecture P-05 reprogramming: reversing glial scar back to neural glial scar back to neural In vivo reprogramming: reversing tissue for brain repair Identification and successful negotiation of a metabolic negotiation of a metabolic Identification and successful reprogramming checkpoint in direct neuronal Mikael simons Göttingen, Germany Cell biology of myelin assembly and disassembly reprogramming of adult glia to neural progenitors to neural progenitors In vivo reprogramming of adult glia and mature neurons Symposium S25 Symposium eterOG eNeItGLIAL H reprogramming of striatal NG2 glia into functional functional of striatal NG2 glia into In vivo reprogramming integrate into local host circuitry neurons that

Bilbao, Spain Chair: Carlos Matute USA Gong Chen Pennsylvania University Park, sergio Gascon Munich, Germany Chun-Li Zhang Dallas, USA Parmar Lund, Sweden Malin 25-04 25-03 25-02 25-01 Auditorium 17:30-18:30 s

s Sala Barria s s 38 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon s Room A1 10:15-12:15 Auditorium 09:00-10:00 SaturD s Sala Barria s s s s s 26-01 27-01 26-04 26-03 26-02 27-02 27-03 Jeffreyrothstein Baltimore,USA I.LorenaArancibia-Carcamo London,UK Johannes Hirrlinger Leipzig, Germany MichaelthomasHeneka Bonn,Germany CharbelMassaad Paris,France Jan-AkeGustafsson Houston,USA JeromeHendriks Diepenbeek,Belgium Chair:Jacquelinetrotter Mainz, Germany

ay, July 18, 2015 Symposia vI eAr NUCLeAr Symposium S26 disease Immune mechanismsofsynapselossinhealthand Beth stevens Boston,USA Plenary lectureP-06 De He OLIGODe Symposium S27 LXr t catenin pathway peripheral nervoussystem:cross-talkwithWnt/beta drugs inAlzheimer’s disease e r death andmajorroleinmetabolicsupport ofneurons Oligodendrolglia inneurodegeneration: unexpected glial e Oligodendroglial supportofaxonal energymetabolism myelinated axons Organizer: robertskoff Detroit,USA Organizers: JeromeHendriks Diepenbeek,Belgium wo novelnuclearreceptorsinglialcellfunction xperimental andclinicaleffectsofPPAr nergy deprivationaltersthenodeofr ole ofLXr MYe AL beta deficiencyattenuatesneuroinflammation t H: AFOr LINA NDr reCePtO t α ION ANDrePAIr Jan-Åke Gustafsson Houston,USA OCYte M andβ GOtteN stOr GOtteN rs INCNs inthemyelinationofcentraland etABOLIs tHe s Y BACKINtHe INFLAMMA M ANDGLOBALBr anvier on t ION, γ modulating POt LIGHt AIN GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 39 ts ON D CNs FFeC terIC NeUrAL IOLOGY HY AND DAMAGe t HOPHYs OLes IN eN t AL r e PA H vassilis Pachnis London, UK elly Hol Utrecht, Netherlands Y AND GUt CUItr terIC GLIA: NOveL merging roles for enteric glia in the gastrointestinal merging roles for enteric glia in the gastrointestinal strOCYtes IN tHe he function of proteolipid protein in mitochondria: the the proteolipid protein in mitochondria: he function of Canada Organizers: Keith sharkey Calgary, Munich, Germany Organizers: swetlana sirko Interactions between enteric glia and neurons in disease Glial functions in enteric neural circuits Development and homeostasis of enteric glial cells Phenotypic plasticity of astrocytes in aging and disease a model of multiple sclerosis Symposium S29 eN CIr e tract Age-related alterations of proliferative capacity and the the Age-related alterations of proliferative capacity and stem cell potential in reactive astrocytes Astrocytes in the aging brain and in Alzheimer’s disease and in Alzheimer’s Astrocytes in the aging brain Symposium S28 Symposium AND tHeIrD CHANGes e AGING-reLAte A t and self-destruction weapon for murder cell’s Astroglial complex senescent phenotype and its phenotype and its Astroglial complex senescent contribution to neurodegeneration East Lansing, USA Brian Gulbransen USA James Goldman New York, Pieter vanden Berghe Leuven, Belgium vassilis Pachnis London, UK swetlana sirko Munich, Germany elly Hol Utrecht, Netherlands Canada Keith sharkey Calgary, Arellano Bilbao, Spain José Julio rodríguez Detroit, USA Detroit, robert skoff 29-04 29-03 29-02 29-01 28-04 28-03 27-04 28-02 28-01 s s Room A4

s s s s

Auditorium s s s 40 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon s s s 13:00-15:00 12:15-13:00 s Room A3 16:00

15:00-16:00 Poster Area Auditorium 30-03 30-02 30-01 30-04

JuanManuelencinas Bilbao,Spain Ameliaeisch Dallas,USA enricLlorensBobadilla Heidelberg,Germany Moastenudd Stockholm,Sweden Chair: KristjanJessen London,UK

hippocampal function Glio- andneurogenesisafterirradiation:implicationsfor r Molecular heterogeneityofadultneuralstemcells lunch Break cord Identity andfunctionofneuralstemcellsinthespinal Symposium S30 Departure t Maiken Nedergaard Copenhagen,Denmark steM Ce e A DIsrUPteDGLIOGe INJUr Poster SessionII Plenary lectureP-07 Organizers: JuanManuelencinas Bilbao,Spain he nightlifeofthebrain QUILIBr eactive neuralstemcellsintheadulthippocampus Y resPONse OFADUL Y LLs s IUM Is Amelia eisch Dallas,USA esseNt NIC/NeUr r tHe tHe IAL FOr t N eUrAL eUrAL OGe NIC

supportedby

Network Glia e.V. was founded in 2011 with the goal of enhancing public awareness and scientific exchange on glial cells.

The association has two major activities:

1. The WEBSITE offers material both for the general public such as • an introduction to glial cells and for glial researchers • a list of animal models for glia research • an online library with classic glia papers • a list of scientific networks in glial research

2. Organizing the EUROPEAN MEETINGS ON GLIAL CELL FUNCTION IN HEALTH AND DISEASE.

Network Glia e.V. Max Delbrück Centrum für Molekulare Medizin (MDC) Berlin-Buch Robert-Rössle-Str. 10, 13125 Berlin, Germany Tel.: +49 30 9406 3336, Email: [email protected]

www.networkglia.eu Picture: Jochen Meier, MDC, Berlin Jochen Meier, Picture:

Sponsored by 42 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon Saturday, July 18 f PoStE t w PoStE Poster Sessions numbers Explanation of abstract riday, July 17 hursday, July 16 =Poster T =IntroductoryCourse I W = Workshop = Symposium S = PlenaryLecture P nu Pr ty PoStE ednesday, July 15 ESEntat of PE of r of tHE MBEr r SESSIon II r SESSIon I r r to r t PIC I on 08

– SErI B A Pr Day ofPoStEr ESEntat Poster SessionI WED &THU Poster SessionII FRI &SAT 09 al nuMBEr I B on 13:00–15:00 13:15–15:15 13:15–15:15 17:15–19:15 GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 43 Cell signaling Neurovascular interactions factors Trophic t04 Cytoskeleton t05 Degenerative disease, toxicity and neuroprotection t06 Extracellular matrix and cell adhesion molecules t07 Gene expression and transcription factors t08 Glial-neuronal interactions t09 Ischemia and hypoxia t10 Myelin t11 Neural stem/progenitor cells t12 Neuroimmunology and neuroinflammation t13 t14 Regeneration and repair t15 receptors, ion channels and gap junctions Transmitter t16 t17 Tumours Poster topics Poster t01 Cell migration t02 Cell proliferation, lineages and differentiation t03 Posters should be mounted on the first day of presentation until 10:00 and are Posters should be mounted on during the whole poster session (two days). They supposed to remain displayed on Thursday (Poster Session I) and directly after must be removed until 16:00 (Poster Session II). the poster session on Saturday Each poster session (120 min) is divided into two parts (each 60 min): uneven Each poster session (120 min) the first part of a session of a day posters with and even serial numbers. In discussed (e.g. T12-03B). In the second 60 min uneven serial numbers will be serial numbers will be discussed (e.g. T12-02B). of a session posters with even There is one poster session per day: poster session I on Wednesday and Thurs- session I on Wednesday session per day: poster There is one poster end- Posters with poster numbers and Saturday. poster session II on Friday day, I), session Thursday (= poster and on Wednesday are displayed ing with an A and Sat- a B are displayed on Friday poster number ending with posters with a days. will be discussed during two session II). So every poster urday (= poster 44 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon adhesion inducedby neuronal thy-1 Par-3 andSyndecan-4areinvolved inastrocyte t01-01a t t w Poster SessionI F. Kirchhoff, A.Scheller X. Bai,N.Zhao,W. Huang,A.Cupido,R.Zhao,J.Hirrlinger, W. Walz, injury subsequent formation ofastrocytes afteracutebrain Evidence foroligodendrocyte dedifferentiation and t02-02a L. Adnani,A.Balakrishnan,S.Li,J.Chan, C. Schuurmans development intheneocortex Dissecting therole ofEtv5inoligodendrocyte t02-01a t02 D. Thatenhorst,C.vonBassewitz,P. Happel,I. D. Dietzel oligodendrocyte progenitor cells water fluxes andaquaporinsinmigrating t01-04a N. Schneble,C.Schmidt,R.Bauer, J.Müller, R.Wetzker represses PI3k Gs protein coupledreceptorsignallingstrongly t01-03a T. cell growth inneuron andastrocyte co-cultures two-Photon polymerized microstructures forguiding t01-02a A. Cárdenas,M.Kong,Alvarez,Valdivia, A. Joki,S.Turunen, M.Kellomäki,S.Narkilahti 01 hursday, July 16 ednesday, July 15 CEll MIGrat DIffErE CEll P rolIfE γ ntI -driven microglial migration at I rat on I on I on, lInEa F. Quest,L.Leyton GES anD 13:15–15:15 17:15–19:15 GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 45 - ra Cheli, V. Spreuer, J. Pasquini, P. Paez J. Pasquini, P. Spreuer, Cheli, V. O’Hagan, P. Bankhead, R. Medina, Y. Dombrowski, D. Fitzgerald Bankhead, R. Medina, Y. O’Hagan, P. , T. Cerrato, E. Parmigiani, K. Leto, E. Fucà, M. Figueres-Oñate, Figueres-Oñate, K. Leto, E. Fucà, M. Cerrato, E. Parmigiani, tion in oligodendrocytes L. Marziali, V. t02-11a matu DMt1 is expressed and required for adequate M.- J. Lee, C. J. Chen, W.- C. Chang, H. Cheng J. Chen, W.- J. Lee, C. M.- t02-10a of Exogenous fGf-1 hault differentiation spinal cord nkX2.2+pre- oPC to nG2+ oPC in a rat model transection t02-09a in vivo astrocytes capacity of reactive Self-renewal L. Lange Canhos, S. Sirko, M. Götz M. Jungblut, S. Reiß, A. Bosio t02-08a allows procedure dissociation automated a novel of astrocytes, isolation efficient immunomagnetic adult rodent from and neurons oligodendrocytes, tissue brain t02-07a endocytosis is critical for Schwann Clathrin-mediated cell myelination U. Suter M. Ghidinelli, E. Tinelli, t02-06a of the as regulators deiminases Peptidylarginine precursor cells of oligodendrocyte epigenetic state L. Nielsen, G. Castelo-Branco M. A. Falcao, S. Marques, M. Varas, t02-05a t cells enhance oligodendrocyte regulatory in vitro differentiation M. Dittmer V. A. Buffo Mascaraque, - L. López t02-04a pheno- astroglial of different generation origin and cerebellum types in the A. Bribian, M. Figueres-Oñate, L. Lopez-Mascaraque M. Figueres-Oñate, A. Bribian, t02-03a glial heterogeneity reveals pattern distribution Clonal 46 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon deprivation oligodendrocyte maturation through gestational iron t02-14a P. E. Papadimitriou, neuronal reprogramming ofastrocytes role ofmicrorna t02-13a C. R. Rose P. B. Moshrefi-Ravasdjani, mouse hippocampus nG2 andS100Bco-localization inthedeveloping t02-12a C. Grit,I. D. Vainchtein, N. Brouwer, B. J. L. Eggen,H. Ex-vivo analysis ofastrocyte subpopulations t02-21a M. Yamada, I.Imayoshi oligodendrocyte differentiation Dynamic regulation ofolig2expressionin t02-20a T. spinal cord role of ascl1 innG2cells theembryonic andadult t02-19a P. A. the correctdifferentiation ofoligodendrocytes SnX27 regulation ofGPr17recyclingisimportantfor t02-18a K. Takahashi, H.Yamazaki, M.Yamada umbilical cordbloodstemcells-derived microglia t02-17a T. Postnatal hyperoxia affectsoPCandGCPproliferation t02-16a K. Salazar synchronous process Ependymal ciliapolarization andIIIG9expressionisa t02-15a V. Scheuer Rosa RosatoSiri,M. E. Guitart,J. M. Pasquini Y. F. Vue , V. Ulivi, , D.Kelenis,J.Johnson , V. , , V. , Meraviglia,A.Fratangeli,F. Valenza, D.Lecca,M. Baeza,F. Martínez,F. Nualart,M.Cifuentes Brockmöller, K.Marggraf,C.Bührer, S.Endesfelder, T. Schmitz Koutsoudaki,K.Aravantinou-Fatorou,D.Thomaidou s mir-124andmir-137indirecting Dublin,K. W. Kafitz,G.Seifert,C.Steinhäuser, W. G. Boddeke P. Abbracchio, GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 47 Rusakov aP-1 and Kim Stewart, D. Kim B, W. W. κ Deitmer, C. Lohr Deitmer, W. Kang, D. Medvedev, M. Medvedev, W. Kraev, N. Kraev, B signaling and induces a neuro- B signaling and induces Bard, I. κ InG Pallen Meuth, M. Doengi, A. Thyssen, J. Henneberger, L. Henneberger, Wang, C. Wang, P) inhibits nf CEll SIGnal Shih, J. -3 in death of crayfish glial and neuronal cells glial and neuronal of crayfish -3 in death

Ly, Y. 03 Savtchenko, C.

t03-05a junctions Calcium-induced calcium release and gap in olfactory large-scale calcium waves mediate cells in situ ensheathing t03-03a factors nf- of transcription Involvement Stat impact photodynamic induced by L. P. M. Stavermann, P. t03-06a alpha (PtPa)-mediated Phosphatase tyrosine Protein differen- is required for oligodendrocyte akt activation and myelination tiation t03-07a in 3D geometry model of astrocyte an interactive S. Kim, M.- H. Yi, E. Zhang, H. Baek, N. Shin, S.- H. Oh, D. E. Zhang, H. Baek, N. Shin, S.- H. Yi, S. Kim, M.- t03-04a factor 15 (GDf15) expression differentiation Growth lesion in the mouse after excitotoxic in astrocytes hippocampus E. Berezhnaya, M. Neginskaya, S. Sharifulina, V. Kovaleva, A. Uzdensky E. Berezhnaya, M. Neginskaya, S. Sharifulina, V. H. Baek, M.- H. Yi, E. Zhang, S. Kim, N. Shin, J. H. Yi, H. Baek, M.- t03-02a inhibitory neuron and stress alters microglial Prenatal spasms in an animal model of infantile development A. Aslanidis, M. Karlstetter, R. Scholz, S. Fauser, C. Fried, H. Neumann, R. Scholz, S. Fauser, A. Aslanidis, M. Karlstetter, Langmann M. Pietsch, T. t S. Förster, A. Crawford, P. Van Wijngaarden, R. Tripathi, W. Richardson, Richardson, W. R. Tripathi, Wijngaarden, Van P. A. Crawford, S. Förster, R. Franklin t03-01a acidic Protein whey Microglia/Macrophage activated (aMwa t02-22a nerve the optic in oPC heterogeneity protective phenotype in microglia protective 48 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon telomerase activity inmurine brain microglia Effect oflong-termcultureontelomerelengthand t03-11a P2X t03-12a M. Stojiljkovic,Q.Ain,T. Bondeva,O.Witte,C.Schmeer N. lesion inthemousehippocampus astrocytic expressionofCtMPfollowing anexcitotoxic t03-09a S. Sharifulina,M.Komandirov, A.Uzdensky in reactionsofglialcellstophotodynamic treatment the role ofDna t03-08a P. E. Zhang,M.- H. Yi, N.Shin,H.Beak,S.Kim,O.- dorsal horninamodelofneuropathic pain Er stressinducesautophagy impairmentinthespinal t03-16a M.- H. Yi alternative activation ofmicroglia the role ofCD200r/foxp3 signalingasenhancerof t03-15a V. L. Xing, dopaminergic regulation ofneuroestrogen synthesis Primary radial glialcellcultureasamodelfor t03-14a F. A. Wyssenbach, disease models reactivity through noX2 activation in alzheimer Integrin b1triggersamyloid b-inducedastrocyte t03-13a F. B. Urzelai, activation inneurons of calciumleadstoantagonic signalingpathways proteins inactivated astroglial cells analysis oftheexpressionwntfamily of t03-17a , F. Gonzalez, S hin, M.- H. Yi, E.Zhang,S.Kim,H.Baek,Lee,D.Kim 7 receptorstimulation inthepresenceorabsence , E.Zhang,N.Shin,H.Baek,S.Kim,D. Trudeau Llavero,A.Artaso,J.Zugaza J. Rodriguez Llavero,J. L. Zugaza,C.Matute,E.Alberdi methylation andhistonedeacetylation W. Y. Kim Kwon,W. Lee,D. W. Kim GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 49 anD toXICIty S. Antonini SE, SE, on M. Cecchini, E DISEa ECtI Iv ton rot rat SkElE uroP yto DEGEnE nE 05 04 C Voccoli, I. Tonazzini, M. Caleo, I. Tonazzini, Voccoli, t05-05a calcium and mitochondrial role of extracellular oligodendrocyte species in psychosine-induced oxygen cell death V. G. Bonetto, I. Charalampopoulos, A. Gravanis, D. Karagogeos t05-04a Bnn27 in synthetic microneurotrophin the of glia in neuroprotection the role demyelination: I. Diaz Aparicio, O. Abiega, S. Beccari, V. Sánchez Zafra, A. Nadjar, Q. Leyrolle, Sánchez Zafra, A. Nadjar, I. Diaz Aparicio, O. Abiega, S. Beccari, V. M. Encinas, A. Sierra S. Layé, M. Vivanco, M. Maletic-Savatic, C. Matute, J. t05-03a uncouples microglial hyperactivity neuronal and self-clearance and leads to delayed phagocytosis inflammation S. Beccari, O. Abiega, I. Diaz-Aparicio, L. Zaldumbide, L. Galbarriatu, S. Beccari, O. Abiega, I. Diaz-Aparicio, L. Zaldumbide, L. M. Encinas, A. Sierra A. Marinas, M. Maletic-Savatic, C. Matute, J. t05-02a mouse is impaired in chronic phagocytosis Microglial with inflammation and human MtlE and correlates O. Abiega Etxabe, S. Beccari, I. Diaz-Aparicio, A. L. Brewster, A. E. Anderson, A. L. Brewster, O. Abiega Etxabe, S. Beccari, I. Diaz-Aparicio, A. M. Encinas, Matute, J. Q. Leyrolle, S. Layé, M. Maletic-Savatic, C. A. Nadjar, A. Sierra t t04-02a does not in oligodendrocytes Dystonin loss-of-function or myelination differentiation, impair migration, S. Gibeault, De Repentigny, S. Kornfeld, S. Bonin, Y. A. Lynch-Godrei, R. Kothary M. M. Azevedo, A. I. Seixas, H. S. Domingues, J. Relvas I. Seixas, H. A. M. M. Azevedo, t05-01a coupling: phagocytosis-apoptosis Microglial a widespread response disturbed in epilepsy t t04-01a oligodendrocyte in involved actin-nucleator an JMy, axon-glia interaction and early extension process 50 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon in the alS-linked neuroinflammatory process Dysregulation oftheS100B-raGE pathway t05-08a T. Erk1/2 signalingandfGfexpressioninretinalgliosis reactive oxygen species(roS)regulate t05-07a M. Celorrio,E.Rojo-Bustamante, S. Aymerich chronic MPtPmousemodel tion inducedby cannabinoid systemmodulation inthe relationship between glialactivation andneuroprotec- t05-06a , F. J. Houtman, Impact ofaging and alzheimer’s disease t05-14a t05-13a L. Fellner, D.Brück,G. K. Wenning, N.Stefanova reduces theinternalization of Macroautophagy dysfunction inoligodendroglial cells t05-12a B. Ettle,S.Reiprich,M.Wegner, E.Masliah,J.Winkler for multiple systematrophy targeting myelin aspotentialinterventional strategy t05-11a K. Dannhausen,M.Karlstetter, A.Caramoy, O.Utermöhlen,T. Langmann M. Molinari, S.Dougan,H.Ploegh,M. L. Feltri,Wrabetz, V. disease ofperipheral myelination the role oftheEraDpathway inthephysiology and t05-09a N. D’Ambrosi,C.Donno,F. Michetti microglial autophagy in retinalmicroglial morphologyandfunctioninmice loss ofacidsphingomyelinase activity causeschanges t05-10a Cotter G. Volpi, C.Ferri,E.Pettinato,Scapin,F. Bianchi, U.DelCarro, , F. , Doonan L. Heppner, M.Jendrach Poster retracted α -synuclein M. D’Antonio β -amyloid on GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 51

2+ positive nG2 cells in the hippo- positive β A. Koulakoff Giralt, R. Rodríguez-Puertas T. -amyloid: implications for neuronal for neuronal implications -amyloid: β Ezan, C. Giaume, treatment as a therapy targeting microglia in a targeting microglia as a therapy treatment β , P. murine model of retinal degeneration murine dysfunction in alzheimer’s disease alzheimer’s in dysfunction campus after status epilepticus campus after status A. Lückoff, A. Caramoy, M. Karlstetter, U. Kalinke, T. Langmann U. Kalinke, T. M. Karlstetter, A. Lückoff, A. Caramoy, t05-22a Ifn A. Llorente Ovejero, J. Martínez-Gardeazabal, M. Moreno, E. González de San A. Llorente Ovejero, J. Martínez-Gardeazabal, M. Moreno, Román, I. Manuel, M. t05-21a mass using maldi-imaging by lipid markers Microglial lesion cholinergic in a basal forebrain spectrometry model D. Lim, A. Grolla, V. Ronco, E. Marcello, A. Iyer, M. Di Luca, A. Verkhratsky, M. Di Luca, A. Verkhratsky, E. Marcello, A. Iyer, Ronco, D. Lim, A. Grolla, V. A. Genazzani E. Aronica, A. t05-20a Ca of astroglial deregulation Calcineurin-mediated t05-19a in effect of an alpha-MSH analogue antioxidant cultures primary astrocytes C. Caruso M. Lasaga, D. Ramirez, L. Carniglia, J. Saba, D. Durand, J. Kyyriäinen, X. E. Ndode-Ekane, A. Pitkänen J. Kyyriäinen, X. t05-18a Expression of PDGfr- K. Kuter, L. Olech, N. A. Dencher L. Olech, N. K. Kuter, C. Yi t05-16a of activation of the chronic Consequences model of of a murine astrocytes in hemichannels disease alzheimer’s A. Kagiava, I. Sargiannidou, S. Bashiardes, J. Richter, N. Schiza, N. J. Richter, S. Bashiardes, A. Kagiava, I. Sargiannidou, K. Kleopa K.A. C. Christodoulou, t05-15a to treat cells to myelinating targeted delivery Gene neuropathies inherited signaling by signaling by t05-17a and dopaminergic dysfunction astrocytes Prolonged in cause small changes degeneration neurons and Iv activity complex I and mitochondrial nigra in substantia assembly supercomplexes 52 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon Glia inPriondiseases t05-27a P. E. Miquel, motor neuron death. Implications for alS reactive astrocytes secreteexosomesthat induce t05-25a L. Barbeito, P. Cassina L. Martinez-Palma,A.Cassina,E.Miquel,V. Lagos-Rodriguez,R.Radi, amyotrophic lateral Sclerosis rat model reduces toxicity tomotorneurons inaged gliafrom Dichloroacetate modulation ofmitochondrial function t05-24a A. Ruiz,E.Alberdi,C. Matute excitotoxic oligodendrocyte death drial andendoplasmicreticulum stressthat exacerbates Mitochondrial division inhibitor1inducesmitochon- t05-32a J. L. Labandeira-Garcia A. I. RodriguezPerez,A.Borrajo,R.Valenzuela, B.Villar-Cheda, M.Guerra, dopaminergic celldegeneration in bothastrocytes andmicroglia. Implications in Modulation ofraSactivity by estrogen takes place t05-31a P. M. Peric, oligodendrocytes ofthe alS rat model Expression ofkir4.1channel inspinalcord t05-30a Ů Parkinson’s disease compensation ofmotordeficits, inrelation toearly dopaminergic systemdegeneration andfunctional Effect ofastrocytes prolonged dysfunction on t05-29a C. O’Sullivan,K.Dev M. Monzón,R. S. Hernández,M.Garcés,R.Sarasa,J. J. Badiola induced demyelination andastrocyte dysfunction activation oftheS1Preceptorattenuates psychosine- t05-28a . Olech,U.Głowacka,K.Kuter Andjus,D.Bataveljic Cassina GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 53

α Filipčík, M. Čente, N. Žilka, M. Novak receptor down-regulation 1 P12-dependent signal promotes pro-Inflammatory pro-Inflammatory P12-dependent signal promotes a D Kovaleva, A. Uzdensky Shinozaki, K. Tanaka, K. Ikenaka, S. Koizumi K. Shinozaki, K. Tanaka, Smolek, P. Runge, M. Trilck, A. Rolfs, M. Frech Runge, M. Trilck, signaling in oligodendrocyte precursor cells precursor oligodendrocyte signaling in t05-41a Hsp27 upregulated degeneration neurofibrillary brain rat in transgenic expression in astrocytes T. M. Kobayashi, H. Konishi, T. Takai, H. Kiyama Takai, M. Kobayashi, H. Konishi, T. polarization in microglia following nerve injury and ex- nerve following in microglia polarization of injured neurons degeneration acerbates V. t05-40a a t05-39a in cray- of no synthase and no production activation of satellite and death survival modulates fish neurons impact photodynamic glial cells induced by M. Xie, X. Chen, C. Qin, Y. Liu, W. Wang Liu, W. M. Xie, X. Chen, C. Qin, Y. t05-38a multi- inhibition provides hydrolase Soluble epoxide after spinal cord injury effects in rats target therapeutic t05-37a of the molecular mecha- the understanding towards matter white nism of vanishing Berkel, C. Van E. Polder, M. Bugiani, L. Wisse, R. Penning, J. Kenney, Abbink T. der Knaap, C. Proud, M. Van M. Altelaar, K. Shrivastava, N. Tentillier, G. Halliday, H. J. Møller, M. Romero-Ramos J. Møller, H. G. Halliday, K. Shrivastava, N. Tentillier, t05-35a astrocytes induce neuroprotective Microglia via P2y Y. t05-36a disease: CD163 receptor in Parkinson’s of the Study biomarker? a prospective K. Schmauder, D. Wiesner, H. Bayer, A. C. Ludolph, A. Witting H. Bayer, D. Wiesner, K. Schmauder, t05-34a factor 1 esters induce hypoxia-induced fumaric acid F. t05-33a C1 type niemann-Pick gliosis in for Indications glia cells iPSC derived patient-specific 54 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon in theoligodendrocyte lineage proteinase withthrombospondin motifs(aDaMtS-4) the expressionofatype-4disintegrinandmetallo- t06-02a astrocytes asacrossroad forplasminogenactivation t06-01a t A. DelGrosso,S.Antonini,I.Tonazzini, G.Signore,M.Cecchini twitcher mice nervous systemcellsandtissuesfrom wild-typeand psychosine accumulation incentral andperipheral Galactosylceramidase (GalC)enzymatic activity and t05-43a R. Pascua-Maestro,D.Sanchez,M.Ganfornina oxidative stress astroglial lysosomal compartmentuponmetabolic and apoD distributioninpH-dependentsubdomainsofthe understanding apoD neuroprotective function: t05-42a B. Elbaz,J. D. Aker, B.Popko T. analysis Human microglia transcriptome andcross-species t07-01a t M. Pruvost,C.Leonetti,E.Maubert,Emery, F. Docagne,D.Vivien A. Briens,I.Bardou,F. Cassé, D. Vivien, M. Veras, T. Pereira,C.Pasqualucci,M. C. Sogayar, E. of late-stage oligodendrocytes Phosphorylation state ofzfP191regulates maturation t07-02a S. K. N. Marie,B. J. L. Eggen

F. 06 07 deA.Galatro,I. R. Holtman, N.Brouwer, P. Sola,G. N. Reis,I. D. Vainchtein, a EXtraCEllular M fa GEn DHESIon M C tor E EXPr This posterhasintheabstractbookIDT05-10B. S ESSIon olECulES anD tranSCr atr F. Docagne IX anD CEll W. G. Boddeke, IPtI

GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 55 Witte, W. (www�goad�education) D): a web-tool to study to study D): a web-tool s are synthesized in the synthesized s are binding 4 (Id4) in adult Michoel, M. Karavalos, M. Stevens, T. Freeman, K. Summers, Michoel, M. Karavalos, M. Stevens, T. Frambach, R. Haenold, K.- H. Herrmann, J. Reichenbach, F. Weih, O. Weih, F. H. Herrmann, J. Reichenbach, Frambach, R. Haenold, K.- t07-09a adult in the healthy diversity transcriptome Microglial regula- in immuno regional heterogeneity reveals brain to sensitivity function and selective tory and metabolic ageing M. Wegner B. Rocamonde Esteve, S. Lepannetier, V. Herranz Pérez, J. García Verdugo, Herranz Pérez, J. García Verdugo, V. B. Rocamonde Esteve, S. Lepannetier, E. Huillard K. Renault, T. t07-10a role of Inhibitor of Dna B. McColl neurogenesis S. Reiprich, S. A. Hoffmann, D. Hos, M. Küspert, R. A. Lang, R. Lovell-Badge, A. Hoffmann, D. Hos, M. Küspert, R. S. Reiprich, S. t07-08a functions in — new its stem cell role beyond Sox2 differentiation oligodendroglial S. Marques, A. Zeisel, S. Samudyata, D. Vanichkina, A. Munoz Manchado, S. Marques, A. Zeisel, S. Samudyata, D. Vanichkina, G. Castelo-Branco S. Linnarsson, J. Hjerling-Leffler, S. Codeluppi, R. Taft, t07-07a of the oligodendrocyte Single-cell transcriptomics in the mouse brain lineage t07-06a factor zfp276 of zinc finger transcription role the during glial development M. Küspert, M. Wegner P. A. Kretz t07-05a a mouse model of Multiple role of glial nf-kB in Sclerosis glia phenotypes in health and disease in health and glia phenotypes Ketelaars, der Geest, K. Duong, P. Noback, M. Bijlsma, M. van I. Holtman, M. E. Boddeke, B. Eggen I. Vainchtein, t07-04a (Goa access Database open Glia nearby glial cells nearby Cefaliello, M. Crispino A. Giuditta, C. t07-03a rna and presynaptic axonal oligodendrocyte

astrocyte microglia

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publicly available glia Itgam (CD11b) transcriptome profiles microarray RNA-seq read count

www.goad.education

GOAD Glia Open Access Database Institute for Life Science & Technology Home Tutorial Contact

˅ Differential Gene Expression Analysis ˅ Quantitative Gene Expression Analysis

microglia vs. microglia vs. whole brain neutrophils read counts microglia vs. microglia vs. astrocytes classical monocytes log(FPKM-values)

The Glia Open Access Database (GOAD) is a comprehensive web-based tool to access and analyze glia transcriptome data. The tool has several features: 1) Differential gene Expression (DE) Analysis, 2) Quantitative gene Expression (QE) analysis and 3) a search utility where gene expression data can be searched based on gene accession numbers or gene symbols. These three features can be accessed using a drop-down menu on the home page:zzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzz www.goad.educationzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzz More information regarding the GOAD tool, expression profiling, and contact information can be found in Holtman et al., which appeared in the March 25th, 2015 issue of Glia, doi: 10.1002/glia.22810.zzzzzzzzzzzzzzzzz Comments, suggestions, and likes can be left at:zzzzzzzzzzzzzzzzzzzzzzz facebook.com/GOADtoolzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzzz GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 57 receptor a onS CtI ra ntE I uronal o3a in oligodendrocyte precursor cell precursor o3a in oligodendrocyte ox Sanchez-Gomez, E. Alberdi, M. Canedo, A. Palomino, Syed, A. Amaral, M. Kotter V. al-nE -mediated gene therapy in dystrophin-Dp71 defi- in dystrophin-Dp71 therapy gene -mediated 08 GlI C. Bohn, H. Jahn, X. Bai, A. Scheller, F. Kirchhoff F. C. Bohn, H. Jahn, X. Bai, A. Scheller, t08-03a upon excitability neuronal controls activity astrocytic ischemia brain t08-04a of purinergic P2y1 receptors in cortical analysis and cerebellar Bergmann glia astrocytes t08-01a (pituicytes) in the hypothalamo- role of astroglia a major brain-to-blood — system neurohypophyseal interface neuro-endocrine A. Perez-Samartin, C. Matute K. Beppu, K. Matsui R. Arellano, M. t08-02a GaBa regulates and glia interaction neuron S. Anbalagan, J. Biran, L. Gordon, M. Gliksberg, E. Wircer, J. Blechman, S. Anbalagan, J. Biran, L. Gordon, M. Gliksberg, E. Wircer, G. Levkowitz t S. Ali Abdulla, Y. t07-13a of f role the differentiation A. Wegener, M. Weider, C. Schmitt, M. Küspert, S. Hillgärtner, M. R. Bösl, M. S. Hillgärtner, C. Schmitt, M. Küspert, M. Weider, A. Wegener, M. Wegner B. Nait-Oumesmar, I. Hermans-Borgmeyer, t07-12a Glia satellite convert directly levels Sox10 Increased cells in vivo into oligodendrocyte-like cient mouse leads to blood-retinal barrier restoration to blood-retinal mouse leads cient Barbe, S. Fouquet, P. Charles-Messance, A. Sene, B. El Mathari, H. O. Vacca, D. Dalkara, A. Rendon A. Sahel, R. Tadayoni, M. Paques, J.- t07-11a aav expression in the oligodendrocyte membrane expression in the oligodendrocyte 58 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon induced by hypercapnia inneonatal mice respiratory columncanmediate respiratory responses D-serine actingonraphe nucleusandventral t08-06a organization andmyelination inzebrafish neuronal ndrg4isessentialfornodesofranvier t08-07a J. Eugenin,S.Beltrán-Castillo,I.Llona,G.Zúñiga,R.vonBernhardi S. Hellwig, ramification after chronic-stress exposure depressive-like behavior andreducedmicroglia hyper- fractalkine-receptor knock-out miceshow unaffected t08-05a S. Jolly, N.Bazargani, N.Pringle,D.Attwell,W. D. Richardson,H.Li receptor Investigation ofaglial-specificG-protein-coupled t08-13a A. HernándezVivanco,S.MederosCrespo, G.PereaParrilla Boosting astrocyte-neuron signalingby opticaltools t08-12a A. Haytin,M.Rudkovskii,Uzdensky A. Hauser, A.Barthelemy, V. Demais,F. glia cells va t08-10a R. Gómez,A.Araque in fragile XSyndrome Glutamatergic astrocyte-neuron signalingisdisrupted t08-09a I. Gobius,L.Morcom,R.Suarez,J.Bunt,E.Sherr, L.Richards and underliestheformation ofthecorpuscallosum spheric midlineisexclusive toeutherianmammals astroglial-mediated remodelingoftheinterhemi- t08-08a L. Fontenas,B.Chambraud,M.Tawk in thecrayfish stretch receptor glial cellssurrounding theaxotomizedsensoryneuron on therole ofCa t08-11a MP expressioninhealthy and glioticmurine Müller S. Brioschi,Dieni,L.Frings,A.Masuch,T. Blank,K.Biber 2+ inapoptosisandnecrosis ofdistant W. Pfrieger, A. Grosche GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 59 -dependent + 4 elevation elevation i ] + clearance via the clearance + L. Laursen Barros F. Malik, I. Neumann, R. Rupprecht, B. Di Benedetto V. Pase? -at + current density in cultured hippocampal neurons in cultured hippocampal current density / k + + Mächler, B. Weber, L. B. Weber, Mächler, Le Marrec-Croq, C. Van Camp, F. Drago, C. Slomianny, P.- E. Sautiere, P.- Drago, C. Slomianny, Camp, F. Le Marrec-Croq, C. Van — a mechanism to increase k a mechanism — mitochondrial pyruvate shunting pyruvate mitochondrial R. Martín, R. Bajo-Grañeras, R. Moratalla, G. Perea, A. Araque M. Jakovcevski, R. Lerchundi, I. Fernández-Moncada, Y. Contreras-Baeza, T. Sotelo-Hitchfeld, Contreras-Baeza, T. R. Lerchundi, I. Fernández-Moncada, Y. P. t08-21a Cell-type specific responses to antidepressants interface glia-neuron of the the epigenetic makeup — t08-20a nH by release mediated lactate astrocytic F. J. Vizioli, C. Lefebvre I. Prada, C. Verderio, C. Linneberg, M. Harboe, t08-18a is preceding CnS myelination axo-glia interaction bidirectional Eph-ephrin signaling by regulated B. R. Larsen, A. Stoica, R. Holm, B. Vilsen, N. MacAulay B. t08-17a [na astrocytic Glutamate-induced t08-16a in developing neurons of apoptotic Glial phagocytosis CnS and mature Levy-Adam K. Mishnaevski, F. Shklover, J. E. Kurant, B. Shklyar, L. Klapal, B. A. Igelhorst, I. D. Dietzel A. Igelhorst, I. L. Klapal, B. t08-15a up-regulate microglia stimulated lipopolysaccharide na C. Karus, M. A. Mondragao, D. Ziemens, C. R. Rose C. A. Mondragao, D. Ziemens, C. Karus, M. t08-14a and duration discharge limit epileptiform astrocytes loads sodium neuronal restrict na t08-22a networks Circuit-specific signaling in astrocyte-neuron in basal ganglia pathways t08-19a a tool microglia: leech (Evs) from vesicles Extracellular neurons for understanding the dialog with damaged 60 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon neural network role ofastrocytes infunctionalmaturation ofhuman t08-31a neural circuitformation astrocyte molecularandfunctionalheterogeneity in t08-25a A. Miyamoto,H.Wake, H.Murakoshi,K.Eto,J.Nabekura postnatal micesomatosensory cortex Microglia contributetodendriticspineformation in t08-24a F. L. MartínezMillán, geomagnetic fields the amblyopic visualcortexsubmittedtomodified Changes ofmicrorna t08-23a S. Narkilahti T. A. Pelkonen, S. Pandit, GaBa Enhanced astroglial GaBa uptake attenuates tonic t08-30a S. Narkilahti T. neuronal networks astrocytes inthedevelopment andfunctionalityof Effect ofhumanpluripotentstemcell-derived t08-29a T. M. Noda, on microglia Glioendocrine systemofthyroid hormoneanditseffect t08-28a M. Neginskaya,E.Berezhnaya,A.Uzdensky radachlorin asaglia-specificphotosensitizer t08-27a A. Nagy, E.Torok, R.Fekete,Z.Kornyei,V. Adam-Vizi,L.Tretter Energy metabolism ofmicroglial cells t08-26a A. paraventricular nucleusneurons inheartfailure Paavilainen,D.Fayuk,A.Pelkonen,M.Mäkinen,L.Ylä-Outinen, V. Molofsky, J.Miller, K.Kelley, E.Ullian,D.Rowitch a inhibitionofpre-sympathetic hypothalamic J. B. Park Yoahimura, L.Jiadai,Y. Yoshii Paavilainen,D.Fayuk, M.Mäkinen,L.Ylä-Outinen, ZalloDíaz,A.PorteroLanda expressioninglialcellsof GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 61 Deitmer W. Barros, J. F. P is modulated by astrocytes in rat in rat astrocytes by P is modulated receptor deletion in the mouse brain receptor deletion in the mouse brain B , A. M. Sebastião , A. tition at the mammalian neuromuscular junction the mammalian neuromuscular tition at t08-36a and inducible of astrocyte-specific analysis GaBa S. Vaz t08-40a BDnf effect on lt hippocampus t08-39a in synaptic plasticity of glial lipid metabolism role the H. Mansvelder, Heistek, J. Timmerman, L. van Deijk, N. Camargo, T. A.- J. Brouwers, D. Gutmann, L. Broersen, A. Smit, M. Verheijen A. Segklia, M.- E. Terzenidou, F. Papastefanaki, E. Douni, R. Matsas F. E. Terzenidou, A. Segklia, M.- t08-38a SlC25 family in a novel a nonsense point mutation carriers causes severe member of mitochondrial disease and epilepsy in mice neurological recessive t08-37a lactate acid-base regulating, of several localization II in anhydrase and Carbonic proteins transporting in mouse hippocampus & neurons astrocytes S. Schütte, A. Weise L. Schlosser, H. M. Jahn, X. Bai, A. Scheller, F. Kirchhoff F. M. Jahn, X. Bai, A. Scheller, H. L. Schlosser, t08-35a in of energy metabolites dynamics Imaging activity neuronal during hippocampal astrocytes Heidtmann, L. I. Ruminot, J. Schmälzle, H. R. Robitaille, H. Darabid t08-34a synaptic plasticity of competingGlial cells influence outcome of synaptic com- terminals and alter the nerve pe R. Reshef, N. Harrari, A. Mizrahi, R. Yirmiya R. Reshef, N. Harrari, t08-33a of the maturation deficiency delays CX3Cr1 Microglial bulb in the olfactory neurons adult born E. Räisänen, K. Lenk, J. Hyttinen E. Räisänen, K. t08-32a network at interactions neuron-astrocyte Modeling level 62 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon and CnSmyelination Contactin-2/ta t08-43a R. Yirmiya T. neurogenesis induced depressive-like behavior andsuppressed Disturbances inmicroglial functioningunderliestress- t08-42a H. Yigit, S.Schick,A.Pataskar, J.Hartwig,V. Tiwari, J.Trotter cells synapses between neurons andnG2-expressingglial revealing thelocally translated mrna t08-41a P. Magistretti, F. Barros,B.Weber P. M. Wyss, level reveal highertransport inastrocytes invivo Cerebral glucoseuptake measurementsonasinglecell t08-47a L. deHoz,S.Moore,K.- A. Nave Myelin andcognition:beyond conductionvelocity t08-46a A. diDomenico,N.Bayó-Puxan,Y. Richaud,A.Raya,Consiglio derived cells disease pathogenesis usingpatient-specific iPSC- Investigating glia-neuron cross-talk duringParkinson´s t08-45a A. Kolta,S.Condamine,P. Morquette, D.Verdier involved inmastication rhythmic burstingby assembliesoftrigeminalneurons astrocytic networks aredeterminantforgeneration of t08-44a L. Zoupi,M.Savvaki,A.Kalemaki,I.Kalafatakis,D.Karagogeos Kreisel,M.Frank,T. Licht,R.Reshf,O.Ben-Menachem-Zidon,S.Maier, Mächler, R.Gutierrez,M.Zünd,S.Lengacher, B.Schneider, G-1 affectsoligodendrocyte populations repertoireat GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 63 Chateil, F. XIa yPoanD H Hirayama, S. Shibata, S. Koizumi aISCHEMI 09 Morizawa, Y. t09-10a CnS in pre-myelinated release mechanisms Glutamate matter white S. Doyle, R. Fern J. G. Zarruk, S. David J. t09-09a of microglia state of the polarization Characterization in a transient macrophages peripheral and infiltrating in mice artery occlusion model Middle Cerebral M. Revuelta, O. Arteaga, H. Montalvo, E. Hilario, A. Martinez, A. Alvarez M. Revuelta, O. Arteaga, H. Montalvo, E. Hilario, A. Martinez, t09-06a the auditory evoked recover treatments antioxidant and reduce morphological potentials alteration in the inferior colliculus after perinatal damage in rat asphyxia t09-05a ischemia after brain astrocytes Phagocytic Y. L. Mazuel, N. Alberti, G. Raffard, S. Sanchez, J.- M. Franconi, J.- L. Mazuel, N. Alberti, G. Raffard, S. Sanchez, J.- K. Bouzier-Sore A.- t09-04a damages: brain ischemic hypoxic neonatal effect of lactate neuroprotective early S. Baltan, S. Katharine, C. Bastian, S. Griffith, S. Brunet S. Baltan, S. Katharine, C. Bastian, t09-03a oxidative and aggravated dysfunction Mitochondrial white of aging increased vulnerability stress mediate to ischemia matter t09-02a in neuroprotection acid confers Docosahexanoic in rats hypoxia-ischemia perinatal L. Urigüen, A. Álvarez, E. Hilario O. Arteaga Cabeza, M. Revuelta, M. Anderova, J. Kriska, D. Kirdajova, P. Honsa Kriska, D. Kirdajova, P. M. Anderova, J. t t09-01a nG2 glia differentiation controls Sonic hedgehog ischemia focal cerebral following 64 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon Dysfunctional nf- t10-08a C. Verderio causes Pelizaeus Merzbacher disease-like disorder Myelin-associated Glycoprotein (MAG) mutation t10-03a M. Y. L. Bang, the nodeofranvier Membrane glycoprotein M6Bisanovel componentof t10-02a T. R. Akkermann, on oligodendrocytes the t10-01a t M.- E. Kastriti, K. A. Kleopa, I. Sargiannidou,D.Karagogeos R. Haenold,C.Engelmann,K.- H. Herrmann,J.Reichenbach,O. M. Fumagalli,Lombardi,E.Bonfanti,Boda,A.Buffo, precursor cells proliferation and differentiation ofoligodendrocyte Microglia-derived extracellular vesicles regulate the t10-07a F. development inmice the influenceofmDomino/p400onSchwann cell t10-06a F. in neuropathic nerve: Pathogenetic orProtective? upregulation ofearly differentiation factors(Id2, Sox2) t10-05a G. Figlia,C.Norrmén,D.Gerber, U.Suter mtor t10-04a Y. Eshed-Eisenbach, V. Meiner, E.Peles N. Elazar, A.Lossos,I.Lerer, N.Schaeren-Wiemmers,M.Harel,T. Geiger, in MultipleSclerosis Differential modulation ofthejuxtaparanodal complex t10-09a F. Weih, A.Kretz Fröb,M.Küspert,E.Sock,Tamm, R.Fukunaga,M.Wegner Florio,C.Scapin,Ferri,E.Pettinato,M. L. Feltri,Wrabetz,M.D’Antonio 10 ta MyElIn C1 regulation ofSchwann cellmyelination M receptor tyro3 actsasapromyelinating factor EshedEisenbach,E.Peles J. Kilpatrick,M. D. Binder κ B andbrain myelin formation P. Abbracchio, W. Witte, GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 65 peut- thera MS a novel -145-5p represents Dunn, R. Doddrell, D. Parkinson Poster retracted mir P. SP-dependent molecular mechanisms involved involved mechanisms molecular SP-dependent Möbius, M. Meschkat, K. Kusch, H. Werner, K.- A. Nave K.- H. Werner, Möbius, M. Meschkat, K. Kusch, t10-18a E. Romanelli, S. Potz, D. Merkler, M. Weber, D. Bishop, T. Misgeld, D. Bishop, T. M. Weber, E. Romanelli, S. Potz, D. Merkler, M. Kerschensteiner S. Roberts, X. t10-17a in an animal of demyelination In vivo pathogenesis sclerosis model of multiple t10-16a cell Schwann in regulating of Sox2 the role analysing and after injury during development myelination t10-15a in 1 (Jab1) binding protein activating role of Jun nervous System (CnS) myelination Central A. Nave, C. Lappe-Siefke, U. Suter, C. Rivellini, E. Porrello, G. Dina, K.- C. Previtali R. Pardi, A. Quattrini, S. K. N. Muth, M. Küspert, E. Sock, M. Wegner K. t10-14a target of DuSP15/vHy as a regulatory Characterization and Myrf of Sox10 t10-13a by and turnover maintenance of myelin Investigation adult mice in inducible MBP knock-out W. E. Mathews, B. Appel t10-12a basis of cholesterol- the mechanistic Investigating myelination mediated ic target through its regulation of critical myelination of critical myelination its regulation ic target through Myrf regulator S. Kornfeld, R. Kothary t10-11a rnaMicro C. Katanov, E. Peles C. Katanov, t10-10a n-wa myelination in PnS 66 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon role ofIre1/Xbp-1pathway inS63delneuropathy t10-21a S. Szuchet,L.Nielsen,M.Domowicz,J.AustinII,D.Arvanitis oligodendrocyte process fusion ofmyelin membranes withintheboundsofan CnS Myelin sheath isstochastically builtby homotypic t10-20a M. Domercq F. experimental autoimmune encephalomyelitis oligodendrocyte survival anditsblockage exacerbates Cystine/glutamate antiporterisessentialfor t10-19a I. Werkman, D.Hoekstra,W. Baron cortical andnon-cortical astrocytes Distinct modulation ofmyelination efficiency by t10-27a C. Stadelmann-Nessler, E.Romanelli, M.Kerschensteiner, M.Simons M.- Molecular mechanism ofmyelin disassembly t10-26a L.- C. Wang, G.Almazan differentiation andmyelination Cdon, acellsurfaceprotein, mediates oligodendrocyte t10-25a H. Wake disruption Impaired motorlearningastheresultofmyelin t10-24a E. Verdiyan, E.Bibineyshvili,N.Kutuzov, G.Maksimov of purinergicreceptors properties duringnerve fiberexcitation andactivation role ofSchwann Cellinregulation ofmyelin sheath t10-23a M. Traka, J.Podojil,D.McCarthy, S.Miller, B.Popko late-onset immune-mediated CnSdemyelination oligodendrocyte death inDTA t10-22a T. Soria,O.Pampliega,J. C. Chara,A.Pérez-Samartín,H.Sato, C. Matute, Touvier, C.Ferri,L.Glimcher, M. L. Feltri,Wrabetz,M.D’Antonio T. , W. Weil, Möbius,T. Ruhwedel,S.Frey, P. Kursula,A.Winkler, miceresultsin GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 67 CEllS tor Abbracchio transcription factors in neural factors in neural transcription nIEM/ProGE P. t Richardson ural S Corsi, S. Ruggieri, R. Tamma, S. Picocci, C. Marinaccio, Corsi, S. Ruggieri, R. Tamma, E 11 n Annese, P. M. Fernandez, M. C. Serrano-Pérez, F. Neira, M. Berjón-Otero, S. Mellado, C. Serrano-Pérez, F. M. Fernandez, M. Tranque E. Doncel-Pérez, E. Cano, P. t11-06a of nfatactivation C. Falcone, C. Filippis, M. Granzotto, A. Mallamaci and neuron sor cells induces astrocyte cur pre tiation differen M. Boccazzi, S. Ceruti, M. t11-04a of nG2+ of the stem cell properties Implementation and the vPa cells: focus on the epigenetic modulator purinergic receptor GPr17 M. Benito, C. Matute, F. Cavaliere M. Benito, C. Matute, F. t11-01a of the neural alterations Molecular and ultrastructural mdx mouse dystrophic stem cells from t11-03a stem a1 receptor shifts neural adenosine of activation to astrogliogenesis neurogenesis from cells fate t11-05a astrogenesis in nSCs modulate Emx2 expression levels Egfr and Fgf9 regulating by rates t11-02a mimics the impact of dysfunction Mitochondrial on hippocampal neurogenesis ageing S. Keiner, Ebert, K. Steib, I. Schäffner, R. Beckervordersandforth, B. J. Moss, J. von Wittgenstein, Eulenburg, N. Toni, V. S. Schuster, C. Redecker, D. Lie G. Larsson, M. Götz, J. Schlachetzki, R. Jagasia, C. N.- A. De Luca, D. Ribatti, B. Nico T. t , W. R. Tripathi t10-28a in oligodendrocytes of myelinating longevity Extreme mouse 68 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon to restorestriatal dysfunction inParkinson patients towards mobilizingthebrain’s own neural stemcells t11-16a neural differentiation sion by humandentalpulpstemcells:implications for neurotransmitter andneurotrophin receptorexpres- t11-10a C. Grudina,Falcone,N.Blecich,A.Mallamaci Foxg1 antagonizes cortico-cerebral astrogenesis t11-09a I. Ferrer, L.Grassner, E.Molina-Holgado D. Garcia-Ovejero,A.Arevalo-Martin,B.Paniagua-Torija, J.Florensa-Vila, like features differs from otherspeciesandshows ependymoma- the ependymal regionoftheadulthumanspinalcord t11-07a M. vanStrien, J.Sluijs,E.Hol S. Beccari,Martín-Suárez,J. M. Encinas, of adulthippocampalneurogenesis Compensatory mechanisms intheage-induced decline t11-15a B. Oppliger, M.Jörger-Messerli, U.Reinhart,D. paracrine factorsorcell-to-cellcontact? cells towards anoligodendroglial fate through Do umbilicalcordstemcellsdirectneural progenitor t11-14a S. Ohlig,Sirko,M.Götz mouse forebrain region-specific differencesinastrocyte plasticityinthe t11-13a D. Ohayon,N.Escalas,P. Cochard, B.Glise,C.Danesin,Soula spinal cord of anovel glialprecursorcellsub-typeintheventral the HS-modifyingenzymeSulf2controls generation t11-12a S. MartínSuárez,R.Valcárcel Martín,J. M. EncinasPérez aged neural stemcellsinthehippocampus t11-11a G. Ibarretxe V. J. Luzuriaga, Uribe-Etxebarria,C.Gomis,P. Chamero,A.Villarroel,F. Unda, A. Sierra V. Surbek,A.Schoeberlein GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 69 B, p38, nrf-2 p38, B, κ anD on I 6 pathway in microglia 6 pathway at nflaMM GyuroIMMunolo uroI E nE 12 n Bloomfield, S. Selvaraj, I. Bonoldi, M. Veronese, D. Owen, N. Kalk, M. Bloomfield, S. Selvaraj, I. Bonoldi, and Ho-1 pathways in inflammatory response in inflammatory and Ho-1 pathways A. Camps Puig, B. Almolda, B. Castellano, B. González t12-07a of cytokines administration Microimmunotherapeutic an animal the clinical symptoms in EaE, improve sclerosis model of multiple t12-06a in the Experi- biomarkers neuroinflammation Early an animal (EaE), allergic Encephalomyelitis tal men model for Multiple Sclerosis N. Borjini, M. Fernandez, L. Giardino, L. Calzà E. Bonfill, M. Dabrowski, B. Kaminska, A. M. Planas E. Bonfill, M. Dabrowski, B. Kaminska, A. t12-05a burst and Il-4 induces an acute pro-inflammatory the by mediated gene program an alternative activates tat Jak1/Jak3/S E. Bondan, R. D. C. Macedo Dos Santos, R. Otton D. E. Bondan, R. t12-04a and oxidative decreases astrogliosis Green tea extract cortex of obese rats stress in the frontal t12-03a and antipsy- of microglia investigation translational ic medication chot P. V. de Paola, O. Howes P. McGuire, Turkheimer, F. M. Bloomfield, B. Bellaver, D. Guerini de Souza, D. Gomes de Souza, A. Quincozes-Santos D. Guerini de B. Bellaver, t12-02a in in glial functionality changes age-related of nf the role hippocampal astrocytes: C. Baksmeier, M. Winter, J. Steckel, M. Harrer-Kuster, N. Goebels, M. Harrer-Kuster, J. Steckel, M. Winter, C. Baksmeier, P. Hartung H.- t12-01a protects immunoglobulin Intravenous slice culture model in an organotypic oligodendrocytes for demyelination t 70 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon experimental autoimmune encephalomyelitis Profiling glialCXCl12receptorexpressionduring t12-14a M. Salzet,P.- E. Sautiere,C.Lefebvre,J.Vizioli protects against myelin damage inEaE the abundance ofmyeloid-derived suppressorcells t12-11a R. Cipriani,J. C. Chara,A.Rodríguez-Antigüedad,Matute neuroinflam ma tion fty720 attenuates excitotoxicity and t12-10a P. J. Church, recovery afterspinalcordinjuryinmice oligodendrocyte lineage cellresponsesandfunctional altered immune signaling(tlr4deficiency)impairs t12-09a E. Eren,K. U. Tufekci, K. B. Isci,S.Genc cells by switching polarization phenotypes Sulforaphane exerts protective effectsinmicroglial t12-16a C. Engelmann,R.Wilke,Grimlowski,M.Riemann,F. Weih, R.Haenold encephalomyelitis in flam mation inexperimentalautoimmune nf-kB pathway inmicroglia isrequiredforbrain activation ofthealternative (relB-dependent) t12-15a F. J. Engele, F. tions inamodelofnerve repair vesicles (Evs)presentingspecificcontentsandfunc- Differentially activated microglia releaseExtracellular t12-13a A. Dolga,L.Matschke,F. Wilhelmy, M.Gold,R.Dodel,N.Decher, C.Culmsee microglial activity andmitochondrial metabolism Sk channels modulate alpha-synuclein-dependent t12-12a D. Clemente,C.Melero-Jerez,F. deCastro , T. Drago, Arab,C.Van Camp,F. LeMarrec-Croq,J.Franck,J.- Pelkner, A.Flügel,M.Puchert Popovich,D.McTigue P. Gimeno, GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 71 -mediated feedback mechanism feedback -mediated β t12-24a tlr4 functions involves microglial over CD14 control an Ifn K. Hanisch C. Fritsche, H. Janova, U.- C. Freria, J. Hall, D. McTigue, P. Popovich P. C. Freria, J. Hall, D. McTigue, t12-23a in signaling CX3Cr1 delection restricts inflammatory and synapse axon sprouting and promotes microglia after spinal cord injury preservation I. Francos-Quijorna, R. Lopéz-Vales t12-22a response after mouse of inflammatory Characterization spinal cord injury t12-21a supplemented Effect of an omega-3/antioxidants and alterations diet on emotional and cognitive with obesity associated processes neuroinflammatory N. Castanon J. Sauvant, A. Aubert, S. Layé, C. Joffre, C. Fourrier, C. Ferrari, B. Silva, M. C. Leal, M. I. Farias, V. Cavaliere Candedo, F. Pitossi F. Cavaliere Candedo, I. Farias, V. C. Leal, M. C. Ferrari, B. Silva, M. t12-20a experimental a novel as cortical inflammation Chronic Influence of Multiple Sclerosis. model of progressive system immune the innate A. Fernández Gil, E. Quintana, P. Velasco, B. de Andres, I. Liste, D. Sancho, Velasco, P. A. Fernández Gil, E. Quintana, M. Cano López E. M. Gaspar, t12-19a in meningeal and are located DnGr-1+ dendritic cells brain of the non-injured plexus membranes choroid L. Fernandez de Cossio Gomez, J. Kim, Q. Leyrolle, A. Nadjar, S. Laye, S. Laye, A. Nadjar, Cossio Gomez, J. Kim, Q. Leyrolle, L. Fernandez de G. Luheshi t12-18a mecha- inflammatory on brain diet effects High fat cells progenitor hypothalamic nisms and i, Z. Környei, î Dénes i, Z. Környei, î î Kittel, Z. Boldogkő R. Fekete, B. Sperlágh, t12-17a in controlling P2y12 microglial of role the brain in the infection virus neurotrophic 72 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon nisms ofneuromyelitis optica vivo modeltodecipherthepathophysiological mecha- autoantibody-driven astrocytopathy: creation ofanin t12-27a W. X. Zhang, relB-dependent epigeneticsilencing Microglia tolerance tolPSismediated by t12-26a S. Fruchon,A.- M. Caminade,C.Turrin, R.Poupot tory properties towards microglia a phosphorous-based dendrimerwithanti-inflamma- t12-25a H. Ikeshima-Kataoka,S.Inui,M.Imamura, M.Yasui f t12-32a M.- astrocytes versus microglia and transcriptional responsestogp130cytokinesin Differential balanceinStat t12-31a S. Gyoneva,D.Kim,A.Katsumoto,B.Lamb,R.Ransohoff after mildtraumatic brain injury Ccr2 deletiondissociates cavity sizeand tau pathology t12-30a A. Greenhalgh,K.Renault,B.McColl,S.David E. Gonzalez-Rey, M.Pedreño,Caro,I.Forte,G.Robledo,J. M. Villaescusa, neurodegeneration Cortistatin: involvement inneuroinflammation and Modulation oftheglialniche by theneuropeptide t12-28a C. Benetollo, N.Auvergnon,S.Vukusic, R.Marignier P. in primaryculture la Culturing adultmousemicroglia t12-29a M. Delgado Giraudon,A.Ruiz,S.Cavagna,C.Watrin, S.Parrot,G.Malleret, unctional analysis of tioninthereactive astrocytes in theinjuredbrain and P. Hsu,S.Rose-John,I. L. Campbell Schaafsma,E.Boddeke,B.Eggen tn-C andGfa 1 andStat P inducedupregu- 3 activation GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 73 L. Heppner -based regulation of neuroinflammatory responses of neuroinflammatory -based regulation N. Kramann, K. Neid, M. L. Ton, E. Fuchs, W. Brück, C. Wegner E. Fuchs, W. L. Ton, N. Kramann, K. Neid, M. t12-41a in marmosets cell infiltration local inflammatory encephalomyelitis with experimental autoimmune and with retinal ganglion cell activation is associated subpial cortical demyelination H. Konishi, M. Kobayashi, T. Takai, H. Kiyama Takai, H. Konishi, M. Kobayashi, T. t12-40a mediated DaP12 pain by of neuropathic augmentation signal in microglia D. Klein, î Patzkó, D. Schreiber, A. van Hauwermeiren, M. Baier, J. Groh, M. Baier, A. van Hauwermeiren, D. Klein, î Patzkó, D. Schreiber, R. Martini L. West, B. t12-39a forms of two alleviates the CSf-1 receptor targeting disease in mice Charcot-Marie-tooth t12-38a disease of the CnS of nG2 in inflammatory role the C. Kurschus, A. Waisman F. Wanke, M. Kitic, K. Karram, N. Israel, F. R. M. H. Khorooshi, M. Thorsen Mørch, T. Hellesøe Holm, C. Tue Berg, R. Truong Berg, R. Truong Hellesøe Holm, C. Tue H. Khorooshi, M. Thorsen Mørch, T. M. R. Owens S. Lienenklaus, T. S. Weiss, Dieu, D. Dræby, t12-36a rna t12-37a a protec- induced within the CnS plays Interferon-beta in EaE role tive I. Jou t12-35a activation in microglial of autophagy role the M. Jendrach, F. K. Isci, E. Eren, Ů Genç t12-34a in inflammasome activation inhibits Sulforaphane cells microglial murine K. Immig, M. Gericke, F. Menzel, F. Merz, M. Krueger, F. Schiefenhövel, Schiefenhövel, F. Merz, M. Krueger, Menzel, F. F. K. Immig, M. Gericke, I. Bechmann K. Biber, K. Hanisch, U. t12-33a and liver lung, spleen, brain, from cells CD11c-positive phenotypes immune site-specific exhibit 74 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon neuroinflammation withoutaffectingcellsurvival IGf1r signalinginoligodendrocytes regulates t12-44a A. Nadjar Q. Leyrolle,C.Lacabanne,V. Labrousse,A.Seré,Aubert,C.Joffre,S.Layé, deficiency Developmental primingofmicroglia by n-3Pufa t12-43a H. Lee,J.Baek,S. J. Lee after peripheral nerve injury Schwann cellactivation and wallerian degeneration toll-like receptor3contributestoinflammatory t12-42a H. Min,J.Hong,Y. H. Jang,Lee, D.Kim,S.- induced intracerebral hemorrhage the bloodbrain barrierandexacerbates collagenase- tlr2-induced astrocyte MMP9activation compromises t12-50a D. Clemente C. Melero-Jerez,M.Suardíaz,Marín-Bañasco,îFernández,F. deCastro, Exploring Ifn- t12-49a t12-47a D. Padro, A.Damont,F. Dolle,J.Llop V. A. Martin, response afterstroke by PEt novel approaches toimage theneuroinflammatory t12-46a W. ence ofselective noS2inhibitoronopioidanalgesia after chronic minocyclineinneurpathic painandinflu- Inducible nitricoxide synthase(noS2)modulation t12-45a I. Bechmann, B.Becher, T. Buch L. Koch, A. Dolga,M.Huber, M.Gold,J.Brüning,C.Culmsee,A.Waisman, G. Locatelli,M.Krueger, B.Ingold-Heppner, O.PrazeresdaCosta, Derived SuppressorCellimmunosuppressive activity damage prevention inEaE:enhancementofMyeloid- Makuch,E.Rojewska,M.Zychowska,B.Przewłocka,J.Mika Gómez-Vallejo, B.Szczupak,A.Arrieta, A.Cano,C.Muñoz, Poster retracted β -mediated new effectsontissue W. Yu, S.Lee, J. Lee s GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 75 H. Neumann Miron V. Schetters, S. Sri, K. Askew, M. Vargas-Caballero, M. Vargas-Caballero, Schetters, S. Sri, K. Askew, T. Guillot, A. Garcia, M. Salou, S. Brouard, D. A. Laplaud Guillot, A. Garcia, M. Salou, S. Brouard, D. Nijland, S. van der Pol, P. van der Valk, H. E. de Vries, J. van Horssen E. de Vries, H. van der Valk, Nijland, S. van der Pol, P. t12-54a in laser-capture evidenced Increased transcripts during astrocytes matter white microdissected in encephalomyelitis experimental autoimmune cell infiltrate to immune relation t12-58a of adrenomedullin in Multiple role therapeutic processes in remyelination involvement Sclerosis: M. Pedreno Molina, I. Forte, L. Carballo, M. Delgado, E. Gonzalez-Rey C. Papaneophytou, I. Sargiannidou, E. Georgiou, C. Abrams, K. Kleopa C. Papaneophytou, I. Sargiannidou, E. Georgiou, C. Abrams, t12-57a autoimmune roles of Cx47 and Cx32 in experimental encephalomyelitis A. Olmos-Alonso, S. Gomez-Nicola D. H. Perry, V. C. Holscher, P. t12-56a microglial Pharmacological inhibition of CSf1r blocks of the progression and prevents proliferation pathology alzheimer’s-like t12-55a sclerosis: bioenergetics in multiple astrocyte and neuroinflammation insights to combat novel -degeneration A. B. Nicot,A. F. t12-53a complement- a microglial by neurodegeneration pathway phagosome J. Kopatz, L. Sinkkonen, R. Balling, L. Bodea, B. Linnartz-Gerlach, A. Mohebiany, A. Waisman A. Mohebiany, G. Ireland, B. Fleiss, J.- C. Becher, D. Rowitch, C. Smith, J. Norman, J. Norman, Rowitch, C. Smith, D. C. Becher, B. Fleiss, J.- G. Ireland, J. Pollard, P. Gressens, t12-51a injury brain in perinatal activation Macrophage t12-52a in microglia by a20 expression and impact of role the neuroinflammation 76 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon is regulated by Sp1 Endothelial protein Creceptorexpressioninmicroglia t12-66a alzheimer’s disease functional properties ofmicroglia inmousemodelsof t12-61a C. Rey, A.Aubert,S.Layé,B.Buaud,C.Vaysse, C.Joffre inflammation resolvins andlipoxin promote resolutionofbrain t12-60a P. E. Quintana, mice mouse modelofaccelerated senescence:theSaMP8 Changes ofmicroglia cellsassociated toaging ina t12-59a D. Baker, B.Eggen,E.Boddeke I. Vainchtein, J.Vinet, S.Al-Izki,G.Pryce,C.Grit,N.Brouwer, S. Amor, chronic-relapsing EaE Microglia areinvolved inapoptoticclearance during t12-67a K. U. Tufekci, E.Eren,H.Ates,S.Genc M. Shiratori-Hayashi,K.Inoue, spinal dorsalhorninchronic itch role ofStat t12-65a S. Spampinato,B.Obermeier, A.Cotleur, A.Love,Y. Takeshita, R.Ransohoff do astrocytes play anessentialrole? Modulation ofS1Preceptorsat theBloodBrain Barrier: t12-64a V. two-photon imaging approach Immune-mediated axono-glialdamage — an invivo t12-63a H. Scheiblich,G.Bicker N. Saiepour carbon monoxide couldbegoodfortheinflamedbrain n t12-62a Siffrin itric oxide-mediated microglial phagocytosis andwhy , T. , A. Bayer, H. Velasco, A.Fernández,H.Mira,M.Vilar, S. M. Arribas,E.Cano 3-dependent reactive astrocytes inthe W. G. Boddeke,U.- K. Hanisch M. Tsuda GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 77 onS CtI ra ntE Marques F. This poster has in the abstract book the ID T12-26B. I urovaSCular E 13 n Rafalski, M. Merlini, J. K. Ryu, C. Syme, D. Davalos, K. Akassoglou Rafalski, M. Merlini, J. Ishizaki, M. Kurachi V. Y. t13-02a responses barrier disruption: microglial Blood-brain function and consequences for neural Multiple Sclerosis: studying lipocalin 2 as a novel 2 as a novel lipocalin studying Multiple Sclerosis: of the disease in the pathophysiology player N. Sousa, M. Correia- S. Neves, S. Mesquita, C. Ferreira, J. Sousa, J. Cerqueira, Neves, J. Palha, t12-72a t12-71a M2 phenotype towards microglia skews tuDCa bile acid receptor coupled the G-protein through GPBar1/tGr5 A. de la Barreda Manso, M. Nieto Sampedro, L. Romero Casás, M. N. Yanguas Ramírez R. Yamasaki, J.- I. Kira J.- R. Yamasaki, t12-70a tactile displaying diathesis a mouse model of atopic in the spinal cord with glial inflammation allodynia J. Vinet, I. D. Vainchtein, C. Spano, C. Giordano, D. Bordini, M. Dominici, C. Spano, C. Giordano, D. Vainchtein, J. Vinet, I. G. Biagini L. Eggen, J. B. t12-69a during and macrophages phenotypes of microglia the epileptogenesis E. van Tilborg, C. Heijnen, M. Benders, F. van Bel, C. Nijboer van Bel, F. C. Heijnen, M. Benders, E. van Tilborg, t12-68a for treatment as a Jnk pathway of the Inhibition injury matter white diffuse perinatal t13-01a microvascular brain from vesicles Extracellular prolifera- survival, endothelial cell cultures promote precursor cells and motility of oligodendrocyte tion, t 78 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon during regeneration functions ofhistonedeacetylasesinSchwann cells t14-01a down ofthebarrierfunctionbloodbrain barrier Microglia have roles inbothofmaturation andbreak t13-05a A. Rodriguez-Contreras,L.Shi ebral cortexof wistar rats brain barrierduringpostnatal development inthecer- correlated withadecreaseinthepermeability ofblood Increase inastrocyte-blood vessel interaction is t13-04a H.- C. Bauer, R. J. M. Franklin,L.Aigner M. Öller, K.Schallmoser, E.Rohde,H. A. Reitsamer, S.Couillard-Despres, F. geni tor cells motes survival ofadultSvz-derived neural stem / CnS lesion-inducedaccumulation ofplatelets pro- t13-03a M. Cayre,B.Brousse,K.Magalon,P. Durbec eration inthemousebrain cells andoligodendrocyte precursorsinmyelin regen- region anddynamic specificitiesofadultneural stem t14-03a J. Cañete-Valdeón lesions remyelination incuprizone-induceddemyelinating macrophages canhappenat theinitiation of M1-to-M2 polarization switch inmicroglia and applying mechanistic modelstoprove that an t14-02a V. t Y. K. Sato, Rivera,I.Kazanis,M.Feichtner, S.Lange,P. Rotheneichner, S.Hainzl, Brügger, S.Ruff,E.Münger, P. Matthias,U.Suter, C.Jacob 14 r Shigemoto-Mogami,K.Hoshikawa,Y. Sekino EGEnE rat I on anD r EP aIr pro - GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 79 Cruz Martinez, J. Jones, S. Martinez Docagne, R. Macrez t14-05a stem cells of mesenchymal injection Intraventricular promotes model, murine demyelinated in a chronic the endogenous stimulating by functional recovery program oligodendrogenic J. Antel, L. Klotz, T. Kuhlmann T. J. Antel, L. Klotz, t14-11a and remyelination role of l-PGDS in PnS regeneration C. Rivellini, S. Previtali, C. Taveggia A. Trimarco, G. Forese, M. Pellegatta, M. E. Floriddia, X. Li, N. Guerot, K. Toskas, F. Barnabe-Heider F. E. Floriddia, X. Li, N. Guerot, K. Toskas, t14-10a self-renewal greater cells show ependymal Juvenile than more oligodendrocytes potential and generate adult cells after spinal cord injury t14-09a of myelin in the control sulfate role of heparan eration gen re Durbec Cayre, P. K. Grobe, M. M. Macchi, C. Zimmer, B. El Waly, O. M. Duman, C. Jacob O. t14-08a histone demeth- plasticity by of oligodendrocyte Control ylases after spinal cord injury S. Devaux, D. Cizkova, L. Slovinska, J. Blasko, M. Nagyova, C. Lefebvre, S. Devaux, D. Cizkova, L. Slovinska, J. Blasko, M. Nagyova, M. Salzet I. Fournier, t14-07a spinal cord injury of rat study proteins Spatio-temporal and glial cells involvement C. Leonetti, J. Bronsard, D. Vivien, D. Clemente, F. de Castro, E. Maubert, D. Clemente, F. C. Leonetti, J. Bronsard, D. Vivien, F. P. t14-06a acts on (tPa) activator plasminogen tissue after remyelination and promotes oligodendrocytes damage matter white S. Albrecht, A. Preisner, Q.- L. Cui, S. Hucke, C. Hartmann, M. M. Taketo, M. Taketo, M. S. Hucke, C. Hartmann, L. Cui, Q.- Preisner, S. Albrecht, A. t14-04a drug indometacin anti-inflammatory non-steroidal remyelination endogenous enhances 80 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon 17 t14-15a M. Nakamura K. Hori,J.Kohyama,T. Sanosaka,A.Iwanami,H.Okano,M.Matsumoto, spinal cord analyses ofepigeneticchange intheinjuredmouse t14-14a J. Göbel,E.Motori,T. M. Eriksson,G.Wani, B.Fernando,M.Bergami sponse toinflammatory insult Mitochondrial regulation ofastrocyte reactivity inre- t14-13a M. Giacci,C.Bartlett,N.Hart,Fitzgerald secondary degeneration following neurotrauma vulnerability andfate ofoligodendroglia inareasof t14-12a H. Liao,J.Ni,G.Liu,Yan, Y. Fang after traumatic brain injury the role ofngr and P75ntronthegliascarformation t14-19a C. Berndt K. Lepka,Volbracht, E.Schaberg,H. regeneration afterneuroinflammatory damage Glutaredoxin 2increasesoligodendroglial capacityfor t14-18a P. follow ing brain injury reprogramming ofastrocytes invitro andinvivo Cend1 andneurogenin-2 drive neuronal t14-17a Y. H. Kim, facilitate recovery from intracerebral hemorrhage alternatively activated brain-infiltrating macrophages t14-16a L. Siklós,U.Gómez-Pinedo,A.Párducz Z. Hoyk,B.Barabási,A.Csondor, T. Martín-Pozas,A. M. PulupaSánchez, mouse hypoglossal nucleus specific changes inP2X7receptorexpressionthe Koutsoudaki,I.Thanou,K.Aravantinou-Fatorou,D.Thomaidou β -estradiol augmentsaxotomy-induced cell-type H. Jang,Min,S. J. Lee P. Hartung,N.Goebels,O.Aktas, GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 81 Dun, P. Edwards, R. Doddrell, A. Shivane, Edwards, R. Doddrell, A. Shivane, Dun, P. P. Liu, F. Yang, Y. Liu, L. Wang Y. Yang, Liu, F. Szabolcsi, M. R. Celio Szabolcsi, M. Mindos, S. Roberts, X.- Papastefanaki, I. Jakovcevski, N. Poulia, N. Djogo, F. Schulz, T. Martinovic, Schulz, T. Papastefanaki, I. Jakovcevski, N. Poulia, N. Djogo, F. A. Vaquié, S. Ruff, E. Münger, C. Pattaroni, N. L. Jeon, C. Lamy, C. Jacob L. Jeon, C. Lamy, C. Pattaroni, N. S. Ruff, E. Münger, A. Vaquié, J. TU, Y. t14-27a and functions in oligodendrocyte Comparison of HDaC cell plasticity after axon injury Schwann V. t14-26a neuronal promotes of astrocytes light activation neurological of stem cells and improves differentiation rats deficit in stroke t14-25a in ependymal expression of parvalbumin De novo ependymal injury promotes cells in response to brain repair remodeling and wound t14-24a injury cell phenotype after nerve of Schwann Control A. Gomez-Sanchez, H. Cabedo C. Gomis-Coloma, J. S. Velasco, F. R. Matsas M. Schachner, H. Weller, Vossmeyer, D. Ciric, G. Loers, T. t14-23a gold coated glycol of polyethylene delivery Intraspinal after spinal recovery functional nanoparticles promotes cord injury T. D. Parkinson t14-22a is critical for peripheral Merlin tumour suppressor the and repair regeneration nerve R. Midha, R. Kumar, J. Biernaskie, S. Sinha, J. A. Stratton S. Sinha, J. J. Biernaskie, R. Midha, R. Kumar, t14-21a dener- and chronically of acutely abilities Differential cells to Schwann and skin derived derived nerve vated remyelination and regeneration support axonal M. McGrath, G. Robertson, M. Zagnoni, M. Riehle, S. Barnett Robertson, M. Zagnoni, M. M. McGrath, G. t14-20a of spinal device microfluidic of an in vitro Development repair for compounds novel injury to identify cord 82 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon is dominated by v-at HCo3--independent pHregulation inastrocytes insitu t15-03a S. Theparambil,Z.Naoshin,A.Thyssen, cortical astrocytes sodium-bicarbonate cotransporter nBCe1inmouse regulation from cytosolicalkalosisby reversed t15-02a L. Deneyer, I.Smolders,K.Wilcox,A.Massie G. Albertini,J.Loewen,Van Liefferinge,E.Bentea,T. Demuyser, E.Merckx, in tMEv modelofviral-induced epilepsy Changes inglialglutamate transporters protein levels t15-01a t E. R. Matarredona P. R. Talaverón, neurospheres andglia Dye couplingbetween cells from subventricular zone t15-08a G. Seifert,S.Höft,Griemsmann,C.Steinhäuser thalamus GaBa receptorsinastrocytes oftheventrobasal Expression offunctionalionotropic glutamate and t15-07a J. A. Orellana,B.Avendaño, T. Montero,C.Chavez,R.vonBernhardi M. Assentoft,S.Kaptan,R. A. Fenton,S. Z. Hua,B.L.deGroot, protonation Gating ofaquaporin4 — phosphorylation versus t15-05a F. T. sic effectofamitriptylineinsciatic nerve-ligated rats Connexin channel inhibitorpromotes theanti-hyper t15-04a D. B. Hansen,N.Garrido-Comas,M.Salter, R.Fern offspring: repercussiononneuronal survival hemichannel openingandactivation ofastro Prenatal exposuretoinflammatory conditionsincreases t15-06a Mouthon,C.Giaume,M.Hamon,Charvériat Jeanson,A. C. Figueiredo,D.Richard,A.Duchène,S.Bourgoin,Picoli, Er r tranSMIttEr 15 anD Ga Fernández,R.Escamilla, îM.Pastor, J. C. Sáez, P JunCtI Pase ECEPtor onS J. Deitmer S, I S, ElS on CHannElS N. MacAulay cytes in the cytes inthe alge- GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 83 Synowitz, ) in the r 1 Lehnardt, M. - -6 secretion in micro Harms, S. oll-like receptor 4 signaling oll-like eceptor-1 (S1P eceptor-1 t expression in astrocytes by by expression in astrocytes r S Euskirchen, C. tor C fa P. Derkow, ourS Hu, K. Kettenmann uM a Dzaye, F. Wolf, H. Wolf, Xin, A. Bonci 17 t 16 troPHIC t15-10a the within of astrocytes characterization functional midbrain ventral young and middle-age rat brain rat and middle-age young E. Blacher, B. Ben Baruch, A. Levy, N. Geva, K. D. Green, S. Garneau-Tsodikova, D. Green, S. Garneau-Tsodikova, N. Geva, K. B. Ben Baruch, A. Levy, E. Blacher, M. Fridman, R. Stein t17-01a Il cells upregulate Glioma-initiating via macrophages glia/brain O. t G. Sheridan, M. Velasco t t16-01a of Changes in expression and localisation Sphingosine 1-Phosphate E. Kougioumtzidou, R. Sprengel, D. Attwell, W. D. Richardson D. Attwell, W. E. Kougioumtzidou, R. Sprengel, t15-12a in oligodendrocyte receptor signalling aMPa ment op devel t15-11a of BDnf mrnaregulation Timmusk T. Tiirik, T. I. Koppel, A. Pennert, K. Jaanson, W. catecholamines J.- C. Wu, C.- H. Chang, C.- K. Liao, C.- C. Shen, C.- C. Wang, H.- S. Wang H.- C. Wang, Shen, C.- C. K. Liao, C.- H. Chang, C.- C.- C. Wu, J.- t15-09a mem- plasma at stability Cx43 HyS-32-enhanced the is caveolae-dependent brane t17-02a discovered a newly by Inhibition of glioma progression CD38 inhibitor S. 84 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon interaction between connexin43andc-Src stem cells:cell-penetrating peptidesbasedonthe a promising therapy against humanglioblastoma t17-06a E. suppresses glioblastomacellgrowth invitro a celldivision cycle7-related protein kinaseinhibitor t17-04a L. D. R. CisnerosCastillo no therapeutic strategy against glioma adoptive M1/M2modulation ofmicroglia asanimmu- t17-03a E. vanBodegraven,O.Stassen,M.Moeton,Strien,P. Robe,E.Hol Gfa t17-09a M. Skubal,Theis,C.Steinhäuser, A.Waha ing proteins inthepathogenesis ofgliomas the role ofCytoplasmicPolyadenylation ElementBind- t17-08a Y. opsin genetransfer light-controlled inhibitionofmalignantgliomaby t17-07a M. JaraízRodríguez,DomínguezPrieto,J.Medina,A.Tabernero , F. Liu, P. Erkan,M.Dinc,E.Eren,J.Allmer, T. Yalcin, S.Genc P inastrocytic tumors Yang, J.Tu, L.Wang aCHuCarro BaSquE CEntEr for nEuroSCIEnCE

Achucarro Basque Center for Neuroscience is devoted to the study of glial cells function in physiology and pathophysiology, a fundamental and translational research centre created by Ikerbasque – the Basque Foundation for Science and the University of the Basque Country (UPV/EHU) in mid-2012. The centre is named after Nicolas Achucarro (Bilbao, 1880–1918), an internationally recognized Basque neuroscientist who made relevant contributions to the biology of glia.

The goal of the Achucarro centre is to perform world-class research in the study of neuron-glia biology in the normal and pathological brain. This research focus will allow us to contribute to the training of future generations of neuroscientists and be an active partner in the dissemination of the human knowledge about the brain.

Our current research programme covers the following areas: – In-depth understanding of the organisation and information processing in neural circuitries; – Identification of genetic and molecular backgrounds of neural circuits during development and ageing; – Characterisation of genetic, molecular and cellular mechanisms of neurodegenerative and autoimmune-mediated brain diseases; and – Translational research aimed at the development of new strategies for the treatment of brain diseases.

For more information: www.achucarro.org | [email protected] 86 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon trop ism controls collective glialmigration Crosstalk between early fate determinantandchemo- t01-01B t Saturday, July 18 f Poster SessionII E. Boda,S.DiMaria, C. Rolando,P. Rosa,V. Taylor, M. and modulation by aging andextrinsicfactors progenitor cellsandoftheirprogeny: characterization Phenotypic heterogeneity ofdividing oligodendrocyte t02-02B P. C. Birck, cyte differentiation Profiling ofthedifferentgenesregulated duringastro- t02-01B t J. Singh,K.Sharma,P. Pillai tor cellsmigration andcytoskeleton reorganization signalling inPDGf-ainducedoligodendrocyte progeni- role ofErkandrhoassociated protein kinase(roCk) t01-03B D. Harlow, K.Saul,H.Komuro,W. Macklin internalization of oligodendrocyte progenitor cellsthrough Glur2 in vivoandregulates glutamate-induced migration of alpha v integrinandthe aMPa glutamate receptor Myelin proteolipid protein mediates theassociation t01-02B T. Gupta,A.Kumar, A.Giangrande 01 02 riday, July 17 CEll MIGrat DIffErE CEll P Heuschling,L.Grandbarbe rolIfE ntI at I rat on I on I on, lInEa GES anD P. Abbracchio,A.Buffo 13:00–15:00 13:15–15:15 GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 87 Gonzalez, A. Franklin J. van Wijngaarden, G. ffrench-Constant, R. Kerninon, P. Witte, C. Redecker W. Kim, J. Sterneckert, H. Zaehres, H. Schöler, H. Schöler, Kim, J. Sterneckert, H. Zaehres, P. Errea, C. Nait Oumesmar, C. Nait Oumesmar, Zhao, B. Niv, T. Steinbach, O. Steinbach, T. Niv, , F. Huang, C. Guzman de la Fuente, O. Huang, X. Bai, L. Schlosser, A. Scheller, F. Kirchhoff F. A. Scheller, Huang, X. Bai, L. Schlosser, K. Kuhlmann t02-11B regain stem cell potential and give astrocytes Mature rise to neurons M. Leist S. Kirner, S. Keiner t02-10B precur- effects on oligodendrocyte activity-dependent in the adult sensori- oligodendrocytes sors and mature motor cortex and corpus callosum W. t02-09B mouse spinal of nG2 glia in the developing Cell fate cord H. Hmidan, C. Parras A. J. t02-08B (Tns3) function in tensin3 of Characterization and remyelination oligodendrogenesis M. Ehrlich, S. Albrecht, K.- T. t02-07B precur- oligodendrocyte regulates rXr-vDr signaling sor cell differentiation t02-05B of human generation rapid and efficient pluripotent stem cells induced from oligodendrocytes t02-04B and cell proliferation inhibition affects Calmodulin pure and lPS-challenged unchallenged in ability vi glial cultures micro K. Dulka, M. Szabo, K. Gulya B. Brone, N. Swinnen, S. Smolders, P. Legendre, J.- M. Rigo Legendre, J.- S. Smolders, P. B. Brone, N. Swinnen, t02-03B of the development embryonic cells during Microglial bench or young team players mature — brain mouse sitters? 88 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon subpopulations inhealthanddisease Identification and characterization ofdistinctastroglia t02-15B C. Marie,M.Frah,Parras oligodendrogenesis and(re)myelination Characterization ofChd7expressionandfunctionin t02-14B R. Lasrado,D.Bell,V. Pachnis using Mosaic Characterization oftherole ofrEt t02-13B K. Konarzewska,B.Wylot,Kaza,J.Ulańska-Poutanen,M.Zawadzka la tion ofoligodendrocyte precursorcellsbiology Interleukin-33 (Il-33)asafactorinvolved intheregu- t02-12B t02-20B V. G. Santos, process S100B modulates oligodendrocyte development t02-19B B. Valentina E. Saracino,M.Nocchetti,A.Sagnella,S.Bonetti,G. T. A. Pistone, L. Pinto,A.Mateus-Pinheiro, R. Machado-Santos,P. Patricio,N. D. Alves, F. in mousecerebellarslices the PI3k/aktinhibitorly t02-16B S. J. Miller, Z.Chen,T. Philips,M.Robinson,R.Sattler, J.Rothstein and functionaldifferentiation invitro nastructured interfacepromoting astrocytes molecular t02-18B J. Oliveira,N.Sousa de deuxintheonsetandremissionfrom depression Cell genesisanddendriticplasticity:aneuroplastic pas t02-17B Pieropan,A. D. Rivera,K.Azim,A. Afonso,A.Barateiro,Fernandes,D.Brites Posati,P. Nicchia,A.Sparaneo,M.Caprini,F. Formaggio, Poster retracted a nalysis withDoubleMarkers (Ma V. 294002 inducesastrogliosis Patel,R.Gibbs,P. Cox,A. M. Butt onentericprogeni P. Ruani,M.Muccini, DM) tors tors GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 89 H. Biber, B. J. L. Eggen, J. B. H. Biber, response to P. 2+ C. Barradas P. InG Tang, R. Enger, V. Jensen, A. E. Thoren, E. A. Nagelhus E. Thoren, E. Jensen, A. V. R. Enger, Tang, CEll SIGnal G. Boddeke W. 03 t03-01B a role play pathway aMPc/Pka hormone and thyroid processes of oligodendroglial in the elongation t H. t03-02B Micrurus lemniscatus from a2 isolated Phospholipases the through inhibits cell proliferation venom snake of p53 in cultured astrocytes activation osmot ic stress osmot K. Ferrari, J. L. Stobart, M. Barrett, B. Weber L. Stobart, K. Ferrari, J. M. Eilert-Olsen, W. t03-05B in response to calcium microdomains astrocyte in vivo sensory stimulation t03-04B unique Ca endfeet show astrocytic C. Dornblut, H. Morrison t03-03B of CPI-17 in Merlin-dependent small GtPase role the in oligodendrocytes regulation S. Castro Afeche, D. Augusto Maria, M. Garcia Laveli da Silva, M. R. Lopes Silva, M. S. Castro Afeche, D. Augusto Maria, M. Garcia Laveli da Sandoval, A. de Souza Imberg, L. Bartlewski, E. Osorio Frare L. O. Felgueiras, C. Oliveira da Silva, V. Younes-Rapozo, E. Giestal de Araújo, Younes-Rapozo, O. Felgueiras, C. Oliveira da Silva, V. L. Tenório, F. A. Pereira da Costa, J. Vailant, t02-23B microglia culture system to study Chimeric oHSCs as phenotypes A. Masuch, K. R. van Weering, A. van der Pijl, H. C. S. Schneider, C. Simon, G. Eichele, M. Götz, L. Dimou C. Simon, G. Eichele, M. S. Schneider, t02-22B in the adult nG2-glia of proliferating Genetic ablation brain M. M. Sartoretti, D. Di Bella, A. Carcagno, G. Lanuza D. Di Bella, A. Carcagno, M. Sartoretti, M. t02-21B in the specification signalling notch Dbx1 and role of astrocytes of spinal of a subset 90 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon with phosphatase PP2a astrocytes Calcium regulation ofmitochondrial respiration in t03-08B A. Garza-Carbajal,S.Brosig,T. Hucho cen tration specificmanner and modulate each othersignalinginatimeandcon- naling pathways insensory-neuron associated glia Il-6 family cytokinesselectively activate differentsig- t03-07B A. Flütsch,K.Henry, S. L. Gonias,W. M. Campana (lrP1) inSchwann cells c-Jun isactivated by lDlreceptor-related protein-1 t03-06B T. V. cytes andneurons Differential secretionofpeptidergic vesicles inastro- t03-13B P. A. Eraso,E.Vicario,L.Pardo,Galea, S. Karges,Bonetti,A. I. BorracheroConejo,A.Pistone,S. D. Quiroga, of calciumsignallinginprimaryrat corticalastrocytes an organicdevice forstimulation andopticalread-out t03-10B B. Juraszek,K.Nalecz in astrocytes: interaction ofcarnitinetransport Cross-talk ofsignalingandenergy-delivering pro t03-09B I. Juaristi,A.delArco,J.Satrustegui,Llorente-Folch astrocytes a functionalmetabotropic-like nMDar inrat cultured t03-12B calcium signalling CrEB: anew player intheregulation ofastrocytic t03-11B M. Muccini,S.Toffanin, V. Benfenati M. Natali,I.Grishin,S.Pecqueur, F. Mercuri,M.Caprini,G.Generali, Fernández-Agulló,F. Aguado , P. MontesdeOcaBalderas, Pla,S.Paco,E.Pozas,N.Lauzurica,M.García-San Frutos,J.Pérez-Clausell, Aguilera R. Masgrau er cesses cesses oC tn2 GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 91 ogy ates ates P study anD -induced -induced β fa G a toXICIty DPH-oxidase medi DPH-oxidase SE, SE, estudines. estudines. t on E DISEa ECtI Iv ton rot rat SkElE uroP yto DEGEnE nE receptor blockade prevents microglia reactivity reactivity microglia prevents receptor blockade 2a stroglial architecture of Squamata as compared to the of Squamata architecture stroglial crosstalk between rock and na rock between crosstalk 05 04 C Quintela, A. Wyssenbach, C. Matute, E. Alberdi Quintela, A. Wyssenbach, myelin dysregulation in alzheimer´s disease models alzheimer´s in dysregulation myelin I. Aires, R. Boia, C. Neves, M. Madeira, F. Ambrósio, A. R. Santiago Ambrósio, A. I. Aires, R. Boia, C. Neves, M. Madeira, F. through cytoskeletal reorganization cytoskeletal through t t04-02B enteric glial morphol changes Stress in mice rapidly B. Lee, K. Sharkey M. Kalman, D. Lorincz t05-01B a the microglial inflammatory response inflammatory the microglial t t04-01B a and of Crocodilia astroglia A. Borrajo, A. I. Rodriguez-Perez, J. Rodriguez-Pallares, P. Garrido-Gil, P. I. Rodriguez-Perez, J. Rodriguez-Pallares, A. Borrajo, A. L. Labandeira-Garcia J. Guerra, J. M. t03-17B a t03-16B initiates myelinophagy, cell autophagy, Schwann injured nerves from clearance myelin Iruarrizaga-Lejarreta, M. Palomo-Irigoyen, M. A. Gomez-Sanchez, L. Carty, J. R. Jessen K. A. Woodhoo, R. Mirsky, M. Varela-Rey, N. Vardjan, M. Kreft, R. Zorec N. Vardjan, T. t03-15B and tonic caMP signalling changes shape astrocyte t03-14B amyloid mediate kinases tyrosine Src-like triggered by elevated hydrostatic pressure hydrostatic elevated triggered by 92 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon Blockade ofadenosine t05-04B C. Benson,M. S. Yousuf, B.Kerr implications forpaininthedisease mitochon drial proteins withinthedorsalspinalcord: EaE isassociated withincreasedexpressionof t05-03B G. Hansel,C.Zenki,E.Kalinine,D.Souza,A.deAssis P. hepatic encephalopathy under acutehyperammonemia inarat modelof neuroprotective effectsofthenucleosideguanosine t05-02B D. O. Souza Y. A. deAssis, adult mice gic excitotoxic conditioninhippocampalslices from neuroprotective effectsofguanosineinanglutamater- t05-09B K. S. Cho, M. Yang, K. J. Kwon,C. cytic cellviability by oxidative stress a role ofSry t05-08B A. Casamassa,C.LaRocca,G.Matarese,L.Annunziato,F. Boscia knocking outthena t05-07B E. Capetillo-Zarate,S.SoléDomenech,D.Cruz,C.Matute,F. R. Maxfield Intravital microglial lysosome imaging t05-06B F. M. Canedo, stress regulation oligodendrocyte death through JnksignalingandEr Inhibition ofCaseinkinase2reduces aMPa-induced t05-05B R. Boia,M.Madeira,F. Elvas,T. Martins,F. Ambrósio,A. R. Santiago autoimmune Encephalomyelitis onset, andincreasestheseverity ofExperimental oligodendrocyte lineage responses, anticipates the the control ofneuroinflammation tion against retinalischemia-reperfusion injurythrough ArendGuazzelli,G.dosSantos,L.Paniz,M. E. Calcagnotto,J.Souza, Llavero,J.Zugaza,C.Matute,M.Sánchez-Gómez Nonose,J.Souza,P. EgonGewehr, P. deFreitas,L.Pellerin, ongender-selective modulation ofastro- + /Ca a 2a Y. 2+ receptorconfersneuropro Shin Exchanger nCX3impairs tec- GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 93 Gould T. Muñoz, A. Gomez, Z. Hozova, P. G-Rozas, Z. Hozova, P. Muñoz, A. Gomez, P. Joensuu, S. Katayama, P. Hakala, E. Einarsdottir, J. Kere, Hakala, E. Einarsdottir, Joensuu, S. Katayama, P. , T. Iram, D. Frenkel t05-13B developing synaptic function at cells regulate Schwann synapses neuromuscular I. Körber E. Lehesjoki A.- T. t05-20B in role a central plays of microglia activation Early myoclonus of progressive the disease pathogenesis EPM1 epilepsy, t05-17B and culture of adult astro- a methodology for isolation Disease research alzheimer’s cytes for t05-16B for the and pharmacological evidence Biochemical the con- — transporters existence of spare glutamate reserve cept of transporter E. Hermans, C. Ingelbrecht, N. Desmet S. Healy, J. McMahon, U. FitzGerald S. Healy, t05-15B mismanage- induces iron loading with ferrocene Iron ment in organotypic hippocampal slices E. Gunnarson, J. Blixt, M. Wanecek D. Heredia, A. Scurry, C. Feng, G. Hennig, D. Heredia, A. Scurry, A. Gaudioso, J. Perucho, E. Edo, M. A. Gaudioso, J. t05-12B potential of and therapeutic Glial cell-dysfunction cellular disease Huntington’s in an early trehalose model C. Easley-Neal, R. Weimer, A. Zarrin R. Weimer, C. Easley-Neal, J. Casarejos A. Rodriguez Navarro, M. A. Fernandez Estevez, J. A. Mena, M. M. t05-11B density microglia reduces treatment anti-Il34 t05-14B edema re- brain dynamic affects the Erythropoietin injury brain traumatic experimental sponse following 94 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon pathogenesis amyloid peptide:implications for alzheimer disease alterations ofastrocytes proteome inducedby beta- t05-23B Pallares, C.Diaz-Ruiz,M. J. Guerra J. L. Labandeira-Garcia,A.Borrajo, I. Rodriguez-Perez,J.Rodriguez- tion ofrho-kinase in neuroprotection ofdopaminergicneurons by inhibi- Inhibition ofmicroglial activity isamajormechanism t05-22B Nessler P. remyelination incuprizone-induceddemyelination Influence ofautoimmune inflammation on t05-21B G. Maura,P. Mariottini,A.Voci, M.Cervelli M. Marcoli,C.Cervetto,L.Vergani, M.Passalacqua,N.Berretta,D’Amelio, oxidase overexpressing mouse:astrocyte-dependency Increased vulnerability to excitotoxicity inspermine t05-27B M. Vidal-Sanz,A.Ambrósio, R. Santiago M. H. Madeira,A.Ortin-Martinez,F. M. Nadal-Nicolas,Agudo-Barriuso, animal model retinal ganglioncelllossinanocularhypertension Caffeine attenuates neuroinflammatory response and t05-26B C. A. Gonçalves, M. deAssis,A. A. Longoni,J.Kolling,C.Siebert,dosSantos,Souza,L.Pettenuzzo, cerebral cortexslicesofrats against homcysteine-inducedcellulardysfunction in neuroprotective effectofpre-treatment withvitaminD t05-25B S. Levison,M.Goodus,N.Ahmed,R.Talwar, D.Buziashvili,K.Pang sive brain injury longing damage andfunctionaldeficitsafteraconcus- lIf haplodeficiencydesynchronizes glialreactivity pro- t05-24B P. Kunz,A.Escher, A.Barrantes-Freer, S.Nessler, W. Brück,C.Stadelmann- Leprince,C.Monoyer, A.Bentaib T. Wyse GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 95

Gasparini, A. Mir, K. Dev Mir, Gasparini, A. Chiozzi, G. Zuliani, F. Di Virgilio Chiozzi, G. Zuliani, F. t05-35B of of nimodipine-dependent inhibition Mechanism interleukin 1-beta production b stimulated amyloid microglia from A. Ambrósio J. M. Sanz,J. P. in the cerebrospinal fluid of patients with fluid of patients let-7 in the cerebrospinal family disease alzheimer’s C. Szabó, î Tomé, Elvas, E. F. H. Madeira, M. Tralhão, R. Santiago, R. Boia, P. A. t05-34B and cell retinal neuroinflammation Caffeine modulates in retinal ischemia survival t05-33B rna micro Specific expression of the neurotoxic O. Peters, S. Lehnardt C. Krüger, C. Schipke, J. Bauer, R. Rößling, K. Derkow, A. D. Rivera, E. Green, R. O. Carare, A. M. Butt O. Carare, A. D. Rivera, E. Green, R. A. t05-32B regulates target of lithium that is a novel oxidase lysyl matter in adult CnS white astrogliogenesis t05-31B amyloid against of microglia role neuroprotective the hippocampal slice cultures in organotypic beta toxicity C. Culmsee, R. Dodel Biber, A. Dolga, K. M. Richter, J. Pham, R. Sattler, J. Rothstein J. Pham, R. Sattler, t05-30B C9ORF72 contribution to of astroglial Characterization (alS) using patient- Sclerosis lateral amyotrophic iPS astrocytes derived A. Osborne, R. Chong, K. Martin A. Osborne, R. t05-29B retinal neuroprotec- factor and growth derived Platelet on microglia tion: the impact S. O’Sullivan, F. t05-28B in human ligand fractalkine of the regulation cytes astro 96 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon drug targetsinParkinson’s disease sirna t05-42B inflammatory effectsonhuman tHP1macrophages low molecularweight polysialic acidshows anti- t05-38B S. Scafidi,J.Jernberg,C.Bowman,M. Wolfgang matic brain injuryinthedeveloping brain astrocytes increasefatty acidoxidation following trau- t05-37B J. Lorenceau,P. Pouget,A.Baron-Van Evercooren N. Sarrazin,S.Gilardeau,P. Moisonnier, S.Rosolen,C.Lamirel,Picaud, human primate opticnerve Demyelination inducesfunctionaldeficitinthenon- t05-36B M. Delgado,Pedreño,E.González-Rey, V. E. Neubrand F. J. Flygt, white matter tracts tion ofoligodendrocyte progenitor cellsinimportant traumatic brain injuryinthemouseleadstoprolifera- t05-41B B. Baird,F. Maxfield S. SoleDomenech,D.Wakefield, E.CapetilloGonzalezdeZárate,D.Cruz, enzymes a t05-40B B. Finsen E. Bouzinova,A.Babcock,J.Hasselstrøm, B. Gramsbergen,O.Wiborg, M. Sivasaravanaparan,Severino,L.ØrumOlesen,R.JordanTenney, ogy andmicrogliosis inthe aPP Effect oflong-termparoxetine treatment on ab pathol- t05-39B A. Shahraz,J.Kopatz,H.Neumann of alzheimer’s disease lzheimer’s amyloid degradation by secretedlysosomal screenofmicroglia toidentifyneuroprotective Clausen, N. Marklund swe PS1 ΔE9 mousemodel GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 97

DHE- on IPtI InG in a ll anD CE IX atr r tranSC anD ESSIon S olECulES Touahri, D. Zinyk, J. Biernaskie, C. Schuurmans D. Zinyk, J. Biernaskie, Touahri, E EXPr tor D. Richardson, H. Li C GEn fa M EXtraCEllular M SIon 07 06 Broccoli, M. Caiazzo, S. Giannelli, P. Valente, G. Lignani, A. Sessa, Valente, Broccoli, M. Caiazzo, S. Giannelli, P. Benfenati J. Rodríguez-Molina, C. Zhang, J. Svaren t07-05B for a subpopu- potential marker of a new Identification of astrocytes lation A. Quiroga, W. t07-06B tGf-B SIGnal with of Sox10 Interactions M. Pawlowski, D. Ortmann, A. Bertero, L. Vallier, M. Kotter M. Pawlowski, D. Ortmann, A. Bertero, L. Vallier, cells Schwann t07-04B efficient induction of oligoden- rapid and highly human pluripotent stem cells by from drocytes programming forward H. Noristani, J. C. Sabourin, Y. Gerber, M. Teigell, A. Sommacal, M. dM Vivanco, M. Teigell, Gerber, C. Sabourin, Y. H. Noristani, J. Perrin F. M. Webber, t07-03B deregu- and is Brca1 is expressed in human microglia alS in human and animal model of lated t07-01B crest progenitor in neural of Etv5 Deciphering the role specification cell fate and Schwann development V. F. A. Balakrishnan, Y. t07-02B into functional astro- of fibroblasts Direct conversion factors defined transcription cytes by t S. Cummings, R. Kothary S. Cummings, t06-01B in the differentiation of oligodendrocyte Investigation lesion microenvironment sclerosis multiple inhibitory in vitro t 98 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon implications glucocorticoid receptorstimulation — metabolic astrocyte-specific transcriptional responseto t07-08B Interleukin-1 signaling local self-renewing ofmicroglia isdependenton t07-09B M. Slezak,R.Przewlocki M. Tertil, S.Golda,A.Wawrzczak-Bargiela, M.Korostynski,Piechota, T. cyte development intheembryonic mousespinalcord Impact oftranscription factorSox13 onoligodendro- t07-07B A. Buttgereit,I.Lelios,R.Nishinakamura, B. Becher, M.Greter factor Sall1 targeting microglia usingthespecifictranscription t07-13B R. Peyroutou,M.Boulpicante,C.Rey, M. Docquier, F. Rassendren H. Hirbec,C.Roubert,I.Richard,Marmai,A.Esclangon,M.Didier, N.Civic, mice revealed by rna Definition ofthemicroglial activome from individual t07-12B F. M. Slezak, type mouse selective geneticmanipulation ofastrocytes inwild- Development andvalidation offlexiblesystemfor t07-11B A. Pujol,E.Galea Z. Zhao,P. Jia,M.Jové,Portero-Otin, M.Ruiz,L.Giménez-Llort,R.Masgrau, L. PardoFernández,A.Schlüter, L. M. Valor, A.Barco,M.Giralt,J.Hidalgo, injury astrocytic CrEBisatherapeutic targetinacutebrain t07-10B T. T. J. Bruttger, K.Karram,S.Woertge, T. Regen,F. Marini,N.Hoppmann,M.Klein, Baroti,E.Sock,M.Wegner, Bopp,M.Prinz,S.Jung,A.Waisman Blank,S.Yona, Y. Wolf, E.Pinteaux,M.Mack,W. Müller, F. Zipp,H.Binder, DeVin,A.Vandebroek, M.Holt C. Stolt seq GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 99 onS CtI ra ntE Abbracchio, S. Ceruti P. eif2b a relevant mouse model for mouse model eif2b a relevant Heary, S. Elkabes Heary, F. I uronal receptors on satellite glial cells as new glial cells as new receptors on satellite 2 2/ko Baykal, R. T. al-nE Castelnovo, S. Melfi, V. Bonalume, A. Faroni, A. Reid, P. Procacci, Bonalume, A. Faroni, A. Reid, V. Castelnovo, S. Melfi, Boesmans, M. M. Hao, V. Pachnis, P. Vanden Berghe Vanden Pachnis, P. M. Hao, V. Boesmans, M. F. 08 GlI Passos, M. Rodrigues potential targets for the pharmacological control of potential targets for the pharmacological control trigeminal sensitization G. Magni, D. Merli, C. Verderio, M. G. Magni, D. Merli, C. Verderio, t08-08B Purinergic P2y L. Magnaghi V. L. Wrabetz, A. Verkhratsky, t08-07B Cells are receptors in Schwann functional GaBa-a null mice in GaBa-B cross-regulated t08-06B are sensitive Glial cells in the enteric nervous system activity to synaptic and non-synaptic neuronal W. M. Baraban, S. Mensch, D. Lyons t08-05B and the formation regulate activity does neuronal How axons in vivo? function of myelinated M. Angelim, L. Maia, A. Amancio-dos-Santos, C. Mouffle, E. Bullier, F. Guinoux, E. Bullier, M. Angelim, L. Maia, A. Amancio-dos-Santos, C. Mouffle, Legendre H. Le Corronc , P. t08-03B is induced by reactivity a differential astrocyte basal rat in nuclei of acid deficiency omega-3 fatty ganglia H. Cardoso, C. Pimentel, E. Santos-Junior, B. Andrade-da-Costa, D. Santana, P. t08-04B was survival neuron ganglia dorsal root Mouse embryo of microglia decreased in the absence C. Acioglu, A. t08-01B rt GlaSt-CreE leukodystrophy the CaCH/vwM t08-02B on 9 antagonist receptor effects of a toll-like opposing direct versus through viability spinal cord neuronal actions astrocyte-mediated R. Abdel Rassoul t 100 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon protective signalsagainst oxaliplatin neurotoxicity neuronal alarminIl-1 t08-12B P. H. deCastroAbrantes, a2a receptors primary astrocytes ismodulated by adenosine a1 and mGlur5-mediated calciumsignallinginrat cortical t08-10B C. Cirillo,A.- S. Desmet,J.Tack, P. Vanden Berghe human entericnervoussystem Glial abnormalities parallel neuronal impairmentin t08-09B L. Pinto,J.Oliveira V. S. Guerra-Gomes, astrocytic dysfunction age-related cognitive impactinatransgenic modelof t08-18B E. Fredrickx,Colombo,G.Dina,A.Quattrini,C.Taveggia System myelination role ofthealpha-secretase t08-17B J. Eyer, C.Fressinaud R. Enger depres sion Dynamics ofionicshiftsincorticalspreading t08-15B E. Dossi,O.Chever, U.Pannasch,M.Derangeon,N.Rouach dynamics astroglial networks modulation ofburstingactivity t08-14B L. DiCesareMannelli,M.Zanardelli,B.Tenci, A.Pacini,C.Ghelardini survival invitro dependent endocytosistopromote theirgrowth and neurofilaments enterinoligodendrocytes viaclathrin- t08-16B E. A. Nagelhus , W. , Tang, G. Sardinha,G.Tavares, J.Correia, M.Martins,N.Sousa, F. Vindedal,V. Jensen,P. J. Helm,R.Sprengel,L. L. Looger, Avelar, M. J. Diógenes,A.Sebastião,S.Vaz α evokes astrocyte-mediated ta CE inCentral nervous GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 101 Petersen, V. levels to a persistent change of function function of change to a persistent levels α Lagos-Rodríguez, L. Martínez-Palma, A. Cassina, P. Cassina Lagos-Rodríguez, L. Martínez-Palma, A. Cassina, P. Perrier, R. Christensen, R. Delgado-Lezama, R. Russo, B. Lykke Lind, B. Lykke R. Christensen, R. Delgado-Lezama, R. Russo, Perrier, F. M. Mäkinen, A. Hyysalo, S. Narkilahti t08-26B of human characterization Electrophysiological oligodendrocyte pluripotent stem cell derived precursor cells R. Lowery, C. Charbonneau, B. Hopkins, A. Majewska C. Charbonneau, B. Hopkins, A. R. Lowery, t08-25B signaling is not required for ocular domi- fractalkine nance plasticity N. Liaudet, E. Bindocci, I. Savtchouk, C. Dürst, A. Volterra N. Lago, V. t08-24B in astrocytes of calcium dynamics 3D volume imaging t08-23B reduced glial of mitochondria modulation Metabolic and in inflammatory and hyperalgesia reactivity pain models chronic neuropathic J.- A. G. Fabbiani, N. Schmitt, M. Lauritzen, E. Loeza Alcocer, E. Meier Carlsen t08-22B from synaptic transmission gate astrocytes sensory afferents unmyelinated K. Janssen, R. De Filippis, S. Hoerner, D. Gomm, C. Kiefer, B. Liebel, V. Lakic, B. Liebel, V. D. Gomm, C. Kiefer, Hoerner, K. Janssen, R. De Filippis, S. M. Bakker H. M. C. Terstappen, G. t08-21B human induced from of astrocytes Generation biology astrocyte to investigate pluripotent stem cells diseases in neurodegenerative t08-20B pluripotent for human nanofiber-platform cells neural stem cell-derived Joki, S. Narkilahti A. Hyysalo, M. Ristola, T. S. Habbas, M. Santello, H. Stubbe, G. Zappia, N. Liaudet, F. Klaus, G. Kollias, Klaus, G. Kollias, N. Liaudet, F. Santello, H. Stubbe, G. Zappia, S. Habbas, M. A. Volterra Suter, Pryce, T. A. Fontana, C. t08-19B in- links that mechanism an astrocyte-dependent tnf creased in cognitive circuits: relevance to multiple sclerosis to multiple circuits: relevance in cognitive 102 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon aptic transmission intheventral hornofthespinalcord Purines releasedfrom astrocytes inhibitexcitatory syn- t08-29B M. Matthey, J.Stockley, C.Watts, R. sor cellsinhealthanddisease neuronal activity dependentregulation ofCnS-precur- t08-28B Gomes I. Matias,L.Diniz,A.Buosi, potential ofastrocytes on cerebral cortexandincreasesthesynaptogenic flavonoid hesperidinmodulates synapseformation t08-27B L. Ylä - Outinen, J.Lekkala,P. Kallio,S.Narkilahti M. Ristola,Mäkinen,A.Hyysalo,L.Sukki, T. Ryynänen,J.Kreutzer, neuron-oligodendrocyte research Development ofco-culture platform for t08-34B R. Furlan,J.Vizioli,D.Cojoc,F. Peruzzi,C.Verderio I. Prada,E.Turola, L.Amin,M.Gabrielli,F. Drago,J.Franck,G.Legname, neurons microvesicles modulates synaptotagminI translation in Glia-to-neuron shuttlingofmir-146aviaextracellular t08-33B V. P. late tobehavioural tinnitusevidence Microglia changes inrat dorsalcochlear nucleuscorre- t08-32B E. Perez,D.Liebl brain injury EphB3 regulates gliotransmission following traumatic t08-31B P. transporter Glt Membrane mobilityoftheastroglial glutamate t08-30B E. M. MeierCarlsen,J.- Perin,A.Venturino, A.Oda,Capetta, G.Colombo,Sanchini,V. Vitale, Michaluk,D.Rusakov Bertone,R.Pizzala -1 F. Perrier P. Araújo,J.Stipursky, F. CarvalhoAlcantara T. Káradóttir GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 103 Garel tion lu Audinat, S. dynamics dynamics 2+ Ginhoux, E. F. Low, P induced by optogenetic P induced by indicators: a high-reso indicators: 2+ at Coralie-Anne, D. Morais Sardinha, S. Guerra Gomes, J. Correia, M. Martins, Morais Sardinha, S. Guerra Gomes, J. Correia, M. Martins, Squarzoni, M.

microglia are potent producers of IGf-1 during are potent producers microglia + Thion, P. Shen, C. Meunier, E. Audiant Shen, C. Meunier, ctivity-dependent neuroglial remodeling enhances neuroglial ctivity-dependent novel open source tool to study astrocytic morphology astrocytic open source tool to study novel he pros and cons of studying astrocytic Ca astrocytic and cons of studying he pros Sardinha, S. Guerra-Gomes, G. Tavares, J. Correia, M. Martins, N. Sousa, J. Correia, M. Martins, N. G. Tavares, Sardinha, S. Guerra-Gomes, two-photon comparative analysis with synthetic dyes with analysis comparative two-photon with genetically-encoded Ca with genetically-encoded t08-43B CD11c Owens A. Wlodarczyk, N. Martin, T. vári, K. J. Kovács î Polyák, D. Kuti, S. Ferenczi, D. Kővári, K. Z. Winkler, M. t08-41B of inhibitory cortical development in the early Microglia circuits activation of astrocytes activation t08-40B a ,G. Tavares V. R. Machado Santos, N. Sousa, L. Pinto, J. Oliveira A. J. Stern, K. Naskar t08-39B a signaling and optimizes adap- glutamate extrasynaptic challenge responses to a physiological neuronal tive t08-42B receptor in hypo- fractalkine of microglial Implication of metabolism lamic control tha t08-38B and release of glutamate W. I. Savtchouk, E. Bindocci, N. Liaudet, A. Agarwal, D. Bergles, A. Volterra I. Savtchouk, E. Bindocci, N. t08-37B t V. J. Oliveira t08-36B of the prefrontal characterization Electrophysiological model in a genetic hippocampus connection cortex and dysfunction of astrocytic N. Ruzafa, X. Pereiro, Y. Filali-Mouncef, E. Vecino Filali-Mouncef, Y. X. Pereiro, N. Ruzafa, t08-35B in vitro cells heterogeneity Müller postnatal neurodevelopment postnatal tHE unIvErSIty of tHE BaSquE Country

The University of the Basque Country (UPV/EHU) is the only public university in the Basque Country. It has three campuses in the three Basque provinces (Biscay, Gipuzkoa and Alava) and covers almost all the areas of knowledge, a vibrant 30-year-old institution with 45,000 students, 5,000 world-class aca- demic staff and state-of-the-art facilities.

The UPV/EHU is the main research institution in the Basque Country, carrying out most of the basic research made in that territory and taking advantage of the good industrial environment in the region.

The UPV/EHU counts with a number of 400 researchers and support personnel working in the different areas of neurosciences, in the Departments of Neuro- sciences; Pharmacology; Cell Biology and Histology; Physiology; and Genetics, Physical Anthropology and Animal Physiology.

EuSkaMPuS – CaMPuS of IntErnatIonal EXCEllEnCE

In 2010, the Spanish Ministry for Education awarded the University of the Basque Country the “Campus of International Excellence” award for its project known as Euskampus. Under the slogan “One University, One Country, One Campus”, Euskampus seeks to combine the excellence and internationalisa- tion of the University and link it to the Country through three (or four?) main areas of specialization or knowledge hubs: Innovative Processes and New Ma- terials; Sustainable Eco-systems and Environmental Technologies; Quality of Life and Healthy Ageing; and Social Innovation.

The Knowledge Hub for Neurosciences, named “Mens Sana”, builds on an old ambition of the research community in this field to boost multidisciplinarity as well as intra- and inter-institutional collaboration. With this perspective, the Hub has defined strategic objectives that must guide the actions by the research and technology institutions working in the field in the Basque Country: UPV/EHU, Achucarro, BCBL, BioCruces, BioDonostia, CIC biomaGUNE, Tecnalia and the three main University Hospitals of the three provinces.

For more information www.ehu.eus | euskampus.ehu.eus GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 105 MacDonald, P. Almeida, D. Gomes de F. XIa yPoanD H Arumugam, Y.- H. Hsieh, M. Gelderblom, K. H. Arumugam, Y.- V.

Mishchenko, E. Mitroshina, T. Shishkina, T. Astrakhanova, Astrakhanova, Shishkina, T. Mishchenko, E. Mitroshina, T. Egon Gewehr, P. de Freitas, G. Müller, R. de Freitas, G. Müller, P. Egon Gewehr, aISCHEMI Carmichael T. 09 Nonose, P. t09-04B the propaga- by is impaired energy metabolism Brain damage tion of focal ischemic G. R. Hill, R. B. Ashman, T. Magnus, C. A. Wells Magnus, C. Ashman, T. B. R. Hill, R. G. ,M. Vedunova T. I. Mukhina t09-08B of Glial cell line-derived properties antihypoxic factor (GDnf) in the acute normobaric neurotrophic in vitro hypoxia A. Uzdensky, S. Demyanenko A. Uzdensky, t09-07B after local photo- in penumbra profiling Protein cortex cerebral infarction in the rat thrombotic t09-06B fac- epidermal growth Differential effects of intranasal zone and dentate on the subventricular tor treatment hypoxia perinatal gyrus after chronic Gallo V. J. Scafidi, J. Edwards, A. O. Rosa, R. Fern A. t09-05B the towards model of focal ischemia: in vitro a new in specific damage understanding of re-oxygenation matter the white Y. Souza, A. Martimbianco de Assis S. Manzanero, T. t09-03B a key is receptor Mincle in microglia immune the stroke in ischemic of tissue damage initiator t09-02B of physiology episode on the an ischemic Impact of Bergmann glial cells H. Daniel, M. Galante O. Chever, R. Helleringer, A. Gleichman, R. Kawaguchi, Z. Guo, M. Sofroniew, P. Yu, G. Coppola, Yu, P. R. Kawaguchi, Z. Guo, M. Sofroniew, A. Gleichman, S. t t09-01B to stroke in response diversity astrocyte 106 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon dimorphism ofmyelin a key role oftheandrogen receptorinthesexual t10-01B t B. Martinecz,G.Szalay, N.Lénárt,E.Csaszar, B.Rózsa,A.Denes responses andbrain injuryaftercerebral ischemia rapid microglial actionscontributetoexcitotoxic t09-10B N. Spratt,M.Nilsson F. ischemia inthemouse microglial-like cellsfollowing focalmotorcortex with secondaryneurodegeneration andsuppresses Chronic stressexacerbates neuronal lossassociated t09-09B A. BernalChico,Manterola,K.- L. Hsu,B.Cravatt,C.Matute,S.Mato cuprizone modelofprimarydemyelination peutic effectsofMaGl and aBHD6 blockade in the Modulation ofendocannabinoid signallingandthera- t10-05B K. Benardais,M.Fauveau,C.Kernion,B.Nait-Oumesmar SoX17 inremyelination Development oftransgenic toolstodeciphertherole of t10-04B A. Amaral,M.GhezuHadera,Kotter, U.Sonnewald cultured oligodendrocytes using phosphate pathway, andmitochondrial activity in Demonstration ofpyruvate carboxylaxion, pentose t10-03B L. Alvey, J.Jones,M.Pickering disease in thetrembler-J mousemodelofCharcotMarie tooth axon path andperipheral nerve structureisaltered t10-02B C. AbiGhanem,Degerny, M.Schumacher, A.Ghoumari R. Walker, I.Zouikr, M.Patience,A.Clarkson,J.Isgaard,S.Johnson, 10 MyElIn 13 C-labelled isotopes GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 107 Murphy, M. Pickering, K. J. Murphy M. Pickering, K. Murphy, P. Sereda W. M signalling promotes oligodendrocyte differ- oligodendrocyte M signalling promotes anthionine ketimine ester provides benefit in a mouse ester provides anthionine ketimine t10-14B decision fate oligodendrocyte CnS-pericytes promote development contributing to myelin and differentiation and repair t10-11B l sclerosis model of multiple J. Relvas S. Lange, A. Guzman De La Fuente, P. Rotheneichner, P. van Wijngaarden, P. Rotheneichner, S. Lange, A. Guzman De La Fuente, P. C. Zhao, S. Couillard-Despres, J. Andrae, A. Trost, A. Gonzalez, H. Tempfer, G. J. Rivera F. Franklin, L. Aigner, J. M. C. Betsholtz, R. t10-13B myelin enhances nefiracetam agent nootropic the repair D. O’Shea, R. A. Keogh, S. E. entiation, maturation, and remyelination after toxic after toxic and remyelination maturation, entiation, injury in culture S. Goudarzi, A. Butt, S. Hafizi t10-12B Gas6/ta D. Feinstein, J. Dupree, K. Hensley t10-10B of identification “processosome”: oligodendrocyte the and myelination of differentiation regulators new O. Braz, I. Seixas, S. A. M. Azevedo, M. Boucanova, S. Domingues, A. Cruz, F. H. A. Dilsizoglu Senol, M. J. Hossain, V. Guillemot, D. Theodorou, C. Lubetzki, J. Hossain, V. A. Dilsizoglu Senol, M. M. Davenne B. G. Brinkmann, S. Quintes, M. Ebert, N. Keric, A. Matz, H. Ehrenreich, N. Keric, A. Matz, H. Ehrenreich, S. Quintes, M. Ebert, G. Brinkmann, B. M. A. Nave, K.- t10-09B initial segment in a of the axon Molecular analysis model of Multiple cuprizone-induced demyelination Sclerosis t10-07B B signalling in the Endothelin receptor for role a novel nervous system peripheral A. Boullerne t10-06B of myelin history the 108 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon cyte precursorcells non-coding rna t10-19B the rat sciatic nerve ci a t10-22B critical forCnSmyelination De novo synthesisoffatty acidsinoligodendrocytes is t10-17B M. MartinezMoreno,A.Olaru,J.Ness,N.Tapinos myelination an Egr2longantisense-rna t10-16B Puertas, K.- L. Hsu,B.Cravatt,C.Matute,S.Mato A. Manterola,Bernal-Chico,M.Canedo,Sánchez-Gómez,R.Rodríguez- novel therapeutic targetsinmultiple sclerosis In vivoandinvitro evaluation ofMaGl and aBHD6 as t10-15B M. Swire,D.Lyons, C.ffrench-Constant the role ofendothelin signallinginmyelination t10-24B E. Segura-Anaya,A.Martínez-Gómez,M.Dent H. Yoon, M.Radulovic,K.Drucker, N. García-Mateo,C.Lillo,M. A. Gijón,R.Murphy, ment dependson apolipoprotein Dfunction Proper myelin maturation duringpostnatal develop- t10-20B S. Samudyata,Marques,D.Vanichkina, G.Castelo-Branco R. Murphy, L.Alvey, J.Jones,K.Murphy, P. L. Montani, r t10-21B in thetrembler-J modelofCharcotMarie tooth disease nefiracetam isineffective inreversing myelin damage t10-18B C. egulatory role ofthethrombin receptorinmyelination quaporin 1islocalizedintheSchmidt-l sures andat theparanodes ofthenodesr F. Semenkovich,U.Suter Dimas,A. L. Dätwiler, D.Moreno,M.Trötzmüller, H. C. Köfeler, s inthedifferentiation ofoligoden I. Scarisbrick M. Pickering regulates peripheral D. Sanchez,M.Ganfornina anterman in- anvier in dro - GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 109 Clausen, Schaeren-Wiemers, Finsen, B. CEllS Lassmann, N. tor Sá-Pereira, B. P and beyond Lundberg, I. Stadelmann, H. on the developing brain on the developing α EM/ProGEnI t Ferrara, L. Anthony C. Lindner, , M. Bando Stolp, L. ural S Linington E methylation in ageing adult oligodendrocyte pro- adult oligodendrocyte in ageing methylation Thuemmler Meinl, C. Lambertsen, D. Breton, H. 11 n t11-03B stem neural of endogenous of the capability Study by excitotoxicity glutamatergic from cells to protect sensing danger signals H. Schäfer Kirchhoff, K.- F. Markwart, A. Scheller, D. Grundmann, D. Simon, F. t11-04B Gfa Enteric Glia: S100b, t11-01B Dna genitor cells K. Granucci, F. E. Butti, D. De Feo, E. Brambilla, M. Bacigaluppi, I. Zanoni, G. Martino t11-02B tnf impact of the A. R. Baror, D. Ma, S. Dietmann, M. Paramor, R. Franklin J M R. Franklin D. Ma, S. Dietmann, M. Paramor, R. Baror, t ,S. Yoshida Y. t10-26B nervous of Peripheral regulators new l-PGDS/GPr44: System myelination t10-27B and axon morphology in demyelination CnS myelin in mouse models and dysmyelination E. Martinelli F. Brambilla, G. Dina, D. Pieragostino, G. Forese, P. M. A. Trimarco, Boneschi, A. Quattrini, C. Taveggia K. t10-25B multiple 9 in factor growth fibroblast of role the of and induction of myelination inhibition sclerosis: environment pro-inflammatory 110 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon role inoligodendroglial fate decision? nuclear translocation inneural stem/progenitor cells: Mesenchymal stemcell-secretedfactorsprevent p57 t11-07B T. N. Iraci, in neural stem/precursorcells Mining thesortingmachinery ofextracellular mirna t11-06B V. J.- P. Hugnot,D.Mamaeva,C.Ripoll,L.Bauchet,F. Perrin,H.Noristani, stem cellniches and injury-activated mouseandhumanspinalcord Molecular andcellularcharacterization ofthedormant t11-05B E. Parmigiani,K.Leto,C.Rolando,A.Buffo, F. Rossi in distinctgerminalniches ofthepostnatal cerebellum fate potentialandclonalanalysis ofneural progenitors t11-13B C. L. Paíno,M. reprogramming from adultrat adiposetissue Myelinating oligodendrocytes generated by directcell t11-12B F. adult guineapigbrain neurogenesis andlateral ventriclar extension inthe t11-11B A. Merlini,D.DeFeo,F. Ruffini, A.Finardi,G.Comi,Martino stem cellsinamousemodelofmultiple sclerosis tion andtherapeutic efficacyoftransplanted neural neuroinflammation influencestheviability, distribu- t11-10B C. López,A.Torres, J.Hernández,X.Navarro,M.Edel J. Jadasz,Domke,L.- S. Spitzhorn,R.Oreffo,H.- neural stemcelltherapy forspinalcordinjury t11-09B Nualart,N.Jara,M.Cifuentes,K.Salazar, F. Martinez Rigau,B.Rothhut Leonardi,A.Enright,S.Pluchino P. Muñoz,L. C. Barrio,D.González-Nieto,L.Vellosillo P. Hartung,J.Adjaye,P. Küry kip2 s

GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 111 - va anD on I receptor modulates microglia acti microglia receptor modulates 1 nflaMMat J. Bajramovic Elvas, M. H. Madeira, T. Martins, C. Cavadas, A. R. Santiago A. Martins, C. Cavadas, H. Madeira, T. Elvas, M. uroI uroIMMunoloGy Lee, E. Stanley, A. Elefanty, S. Petratos A. Elefanty, Lee, E. Stanley, E Y. nE 12 n t12-03B and activation Differential inflammasome expression in glial cells tion in the rat retina tion in the rat C. van der Putten, E. Zuiderwijk-Sick, J. Veth, S. Burm, E. Pasini, H. Kuipers, C. van der Putten, E. Zuiderwijk-Sick, J. Veth, van den P. van der Valk, M. van Eggermond, L. van Straalen, I. Kondova, P. Elsen, S. Amor, t12-04B cytokine tlr-induced represses Il4 exposure broadly responses in primary microglia A. Gustin, M. Kirchmeyer, E. Koncina, P. Felten, P. Heuschling, C. Dostert Felten, P. E. Koncina, P. A. Gustin, M. Kirchmeyer, A. Ambrósio, F. t12-01B damage role of glial cells in the neuroinflammatory receptors tlrs/nlrs ethanol through induced by t12-02B y y neuropeptide S. Alfonso-Loeches, J. Ureña-Peralta, M. Morillo-Bargues, J. Oliver-de la Cruz, J. Oliver-de S. Alfonso-Loeches, J. Ureña-Peralta, M. Morillo-Bargues, U. Gómez-Pinedo, C. Guerri M. Kim, J. t t11-16B oligodendrocytes myelinating of Efficient derivation stem cell reporter embryonic nkX2.1-GfP human from line t11-15B reactive stem cell-derived of neural Characterization mice in lPar1-EGfP astrocytes M. Encinas S. Martín-Suárez, J. R. Valcárcel-Martín, D. Safina, R. Romeo, F. Schlitt, F. Edenhofer, A. Faissner Edenhofer, F. Schlitt, F. Romeo, D. Safina, R. t11-14B protein 1 receptor-related lipoprotein density low stem cells’ of neural modulator novel a — (lrP1) and spinal cord cortex developing in the properties 112 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon and demyelination antibody andcomplement-mediated glialresponse t12-06B of inflammatory effectsin young and aged hippo Intracerebroventricular insulinpresentsdifferentneu t12-07B C. Berg,R.Khorooshi,N.Asgari,Linington,P. B. Morgan,T. Owens P. E. Saavedra, leading totargetedphagoptosis inthebrain Phagocytic gliapsesprecedecellularelimination t12-05B R. deHoz,A. I. Ramirez, B. I. Gallego,B.Rojas,J. J. Salazar, F. J. Valiente- microglial processes occursbeyond theGCl increased microglial cellnumberandretraction of In miceretinacontralateral toexperimentalglaucoma t12-13B H. Dambach,Z.Moinfar, F. Corvace,E.Förster, P. M. Faustmann on glialproperties inastrocyte/microglia co-cultures Influence oftheanti-epilepticdruglacosamide(lCM) t12-12B F. G. Casella, neu Microglial Microvescicles astherapeutic vector for t12-10B T. induced Microglia activation astrocytes asakey partnerinMethamphetamine- t12-09B J. Bajramovic S. Burm,E.Zuiderwijk-Sick,A.‘tJong,C.vanderPutten,J.Veth, I.Kondova, Inflammasome-induced Il-1 t12-08B L. C. BrancoHaas,A.KopczynskideCarvalho,PastorisMüller, dependent oninflammatory caspases characterized by delayed kineticsandis only partially J. M. Ramirez Soriano, M.Aviles-Trigueros, M. Canedo,C. C. Portugal,R.Socodato,J.Relvas,T. Summavielle V. w CruzPortela ro istar rats inflammation Colombo,R.Furlan Casanova, C. Barcia P. Villegas-Perez,M.Vidal-Sanz, A.Triviño, β secretioninmicroglia is campus campus ro - GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 113 Montamé, S lesions Krishnan, A. Le Charpentier, Le Charpentier, Gressens Sigaut, M. Dombrowski Y. Schwendimann, T. Schang, S. L. P. Soussi-Yanicostas, Lebon, L. Hyman Hagberg, N. Regen, A. Waisman T. Hennebert, S. Morrison, E. Hudry, M. Arbel-Ornath, B. J. Bacskai, T. Gómez-Isla, J. Bacskai, T. M. Arbel-Ornath, B. Morrison, E. Hudry, Van Steenwinckel, A. Steenwinckel, Van D. Frenkel M. Madsen, R. Brambilla Edwards, H. Fleiss, J. Degos, O. D. Gudi, L. Gai, L. Salinas Tejedor, V. Herder, W. Baumgärtner, M. Stangel, Baumgärtner, W. Herder, V. Gudi, L. Gai, L. Salinas Tejedor,

Skripuletz V. A. t12-17B factor growth transforming overexpressing astrocytes of beta and degradation increase uptake beta1 show amyloid t12-16B microglia inhibition promotes wnt signaling Microglial blockade maturation and oligodendrocyte activation J. Hauptmann, T. t12-21B CnS endothelial Il-1 signaling drives neuroinflammation V. T. t12-20B axonal to study marker is a suitable Synaptophysin induced during experimentally damage transport myelination de t12-19B in receptor 2 signaling factor necrosis tumor role of im- in experimental auto and macrophages microglia encephalomyelitis mune H. Gao, P. E. Galea, W. B. E. Stanley, H. S. Amram, B. A. Fernandes, C. Caldeira, A. S. Falcão, C. Cunha, A. R. Vaz, D. Brites Vaz, R. C. Cunha, A. S. Falcão, C. Caldeira, A. A. Fernandes, S. Fleville, M. Dittmer, D. Fitzgerald, D. Fitzgerald, M. Dittmer, S. Fleville, t12-14B Cn in demyelinated expression Inflammasome t12-18B aPP/PS1 in analysis spatial physics-based a statistical to amyloid- do not migrate astrocytes that mice reveals beta plaques t12-15B to microglia related profile gene expression temporal mice in 3xtgaD reactivity 114 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon differentiation encephalomyelitis by promoting oligodendrocyte tnf-dependent repairinexperimentalautoimmune oligodendroglial tnfr2 mediates transmembrane t12-24B tuberal hypothalamic development the effectofmicroglia onprogenitor cellsduring t12-27B Sclerosis Elucidating theroles offGfsignalinginMultiple t12-29B F. E. Laudati,C.DelloRusso,P. Navarra, glia andinhumanglioma the role ofmtor t12-23B C. Lacabanne,J.Kim,A.Benmamar--Badel, S.Layé,G.Luheshi brain inflammatory responsetosystemiclPSinmice Intrahippocampal clodronate administration altersthe t12-22B D. McElroy, K.Thuemmler, M.Lindner, C.Schuh,H.Lassman, C.Linington M. Domercq, sclerosis a novel imaging approach tomonitormultiple t12-28B C. Marsters,Q.Pittman,D.Kurrasch Neves, J.Palha, S. Neves,Mesquita,C.Ferreira,J.Sousa,Cerqueira,N.M.Correia- player inthepathophysiology ofthedisease Multiple Sclerosis: studying lipocalin2asanovel t12-26B J. vanHorssen T. J. Mailleux, liver Xreceptoractivation inMSlesions t12-25B P. Soria,B.Szczupak,S.Plaza,A.Arrieta,T. Reese,J. Llop,C.Matute Madsen,D.Motti,Szymkowski,K.Lambertsen,J.Bethea,R.Brambilla A. Martin,N.Vázquez-Villoldo, D.Padro, V. Gómez-Vallejo, Vanmierlo, J.Bogie,E.Wouters, P. Stinissen,J.Hendriks, F. Marques kinaseinglioma-activated rat micro- L. Lisi GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 115 P mutations in P mutations C. Meier deficiency neuroprotective in EaE? deficiency neuroprotective β the radio-resistant immune cell of the brain immune the radio-resistant Valente, P. Castillo, J. Matalonga, M. Straccia, J. M. Canals, C. Solà, J. Saura Castillo, J. Matalonga, M. Straccia, J. P. Valente, Menzel, K. Immig, F. Merz, I. Bechmann Merz, F. Menzel, K. Immig, in vitro its implications mouse model to study a new and in vivo M. Pulido-Salgado, J. Vidal-Taboada, A. G. García-Díaz Barriga, J. Serratosa, A. M. Pulido-Salgado, J. Vidal-Taboada, T. t12-37B C/EBP Is microglial t12-36B (SvCt2): a key C co-transporter-2 vitamin Sodium the physiology molecule for microglia Coreixas, Martins, V. T. Canedo, C. Silva, C. Portugal, R. Socodato, T. C. R. Paes-de-Carvalho, Young, R. Santiago, P. A. C. Loiola, B. Gess, D. Röhr, E. A. Ambrósio, J. Relvas I. Pla-Navarro, D. Bevan, M. Mogensen, M. Hajihosseini, M. Lee, J. Gavrilovic I. Pla-Navarro, D. Bevan, M. Mogensen, M. Hajihosseini, t12-35B of metallo- Sonic hedgehog and vitamin D modulation endothelial junction expression and in vitro proteinase integrity alexander disease t12-34B stroke in human ischemic CD163+ Macrophages M. Planas Miró, E. Gelpi, A. Chamorro, A. J. Pedragosa, X. Urra, F. M. Olabarria, M. Putilina, J. E. Goldman M. Olabarria, M. Putilina, J. t12-33B by Gfa response caused Inflammatory t12-32B iso- disorders; towards in psychiatric Glial changes brain the post-mortem human glia from lating I. Huitinga M. Mizee, K. Schuurman, J. Hamann, F. N. Hainz, S. Semar, T. Tschernig, Tschernig, T. N. Hainz, S. Semar, t12-30B and symptoms clinical prevents application Probenecid of experimental model in a mouse infiltration t cell encephalomyelitis autoimmune t12-31B — Microglia 116 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon microglia isrestrictedtoeyes withocularhypertension contra lateral toexperimentalglaucoma butrod-like Microglial activation isdectectedinmiceretina t12-44B hypertension contralateral retinatoexperimentalunilateral ocular Microglial activation beyond theganglion-celllayer in t12-40B W. Y. S. Rakic, in t t12-39B Neto, C.da-Silva,M.Mitkovski,E.Del-Bel R. Raisman-Vozari, M.Bortolanza,R.Cavalcanti-Kiwiatkoski,F. E. Padovan- inhibitor inarat modelofParkinson’s disease dyskinesia andblocked by anitricoxide synthase Glial activation isassociated withl-DoPa induced t12-38B B. Rojas, I. Gallego,R.deHoz,A. I. Ramirez,J. J. Salazar, F. J. Valiente- Bayon, C.Andrade,N.Mahy, M. Martinez-Moreno,Batlle,F. J. Ortega, M. Vidal-Taboada, J.Gimeno- rat hippocampus neurogenesis aftern Diazoxide attenuates neuroinflammation anden t12-43B A. Robinson,J.Rodgers,S.Miller deleterious effectsonoligodendrocyte lineage cells Pathologic t cellcytokineshave bothbeneficialand t12-42B B. Castellano M. RecasensTorné, K.Shrivastava,B.Almolda,I.Campbell,Gonzàlez, A. I. Ramirez,B. I. Gallego,J. J. Salazar, B.Rojas,R.deHoz,F. J. Valiente- J. M. Ramirez Soriano, M.Aviles-Trigueros, M.Vidal-Sanz, M. perforant pathway transection sion of trEM2 andCD200rinactivated microglia after astrocyte-targeted Il10production modifiesexpres- t12-41B J. M. Ramirez Soriano, M.Aviles-Trigueros, M. he effectsofsystemicinfectiononneuroinflam Stewart,D.Boche a lzheimer’s disease M. A. Hung,J.Wild,Nicoll,S.Love,C.Holmes,V. H. Perry, M. J. Rodriguez MD P. Villegas-Perez,M.Vidal-Sanz,A.Triviño, a -induced excito P. Villegas-Perez,A.Triviño, tox ic ity in the ity inthe ma hances hances tion tion GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 117 Hartung, O. Aktas, P. Santa Cecilia, S. B. Socias, M. O. Ouidja, E. Del-Bel, Socias, M. B. Santa Cecilia, S. V.

Michel, T. M. Cunha, R. Raisman-Vozari Michel, T. P.

Prozorovski Semenoff, K. Chapple, K. Thuemmler, J. Edgar, C. Linington J. Edgar, Semenoff, K. Chapple, K. Thuemmler, P. T. t12-51B injury induces mediated autoantibody non-lytic cultures expression in myelinating chemokine J. E. Sepulveda Diaz,J. F. t12-52B response of decreases the inflammatory Doxycycline cells microglial lPS-treated T. t12-50B in the wnt signalling pathway of the Characterization autoimmune hippocampus of mice with experimental encephalomyelitis J. Ingwersen, H.- Schröter, B. Koop, F. R. Schneider, I. Sá-Pereira, J. Roodselaar, D. C. Anthony, H. B. Stolp H. C. Anthony, D. I. Sá-Pereira, J. Roodselaar, t12-49B population macrophage intravascular an age-specific of susceptibility window with the murine is associated to CnS inflammation C. Sanson, M. El Behi, C. Bachelin, L. Guillot-Noel, N. Sarrazin, B. Stankoff, C. Sanson, M. El Behi, C. Bachelin, L. Guillot-Noel, N. Sarrazin, Zujovic I. Rebeix, B. Fontaine, V. t12-48B with crosstalk lymphocytes patient’s Multiple sclerosis process cells impacts the remyelination microglial R. Sanchez Gonzalez, M. Irmler, J. Beckers, M. Götz, J. Ninkovic R. Sanchez Gonzalez, M. Irmler, t12-47B de- injury brain after adult system changes Immune fine scar formation t12-46B in an animal and inflammation of microglia role the alS model of Furlan, N. Riva, A. Quattrini, G. Comi, G. Martino, C. Rossi, A. Bergamaschi, R. L. Muzio L. Romero-Ramirez, N. Yanguas-Casás, A. Martínez-Vázquez, M. de la Barreda M. de la Barreda A. Martínez-Vázquez, N. Yanguas-Casás, L. Romero-Ramirez, M. Nieto-Sampedro Manso, M. Gilbert, t12-45B other o-acety- and of neurostatin Structure-activity on drugs as anti-inflammatory gangliosides lated cells microglial 118 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon the 6-oHDa Parkinson’s diseasemodel anti-inflammatory therapy viaCD163-macrophages in t12-59B disorders? ma ter nal immune activation andneuropsychiatric Can embryonic microglia bridgethegapbetween t12-56B J. Slusarczyk,E.Trojan, K.Glombik,J.Mika,A.Basta-Kaim and enhancedinflammatory processes inthe rat brain Prenatal stresscausesprolonged microglial activation t12-55B E. Sikkema,J.Stoffels,F. Basedow, W. Baron,D.Hoekstra differentiation ofoligodendrocytes phenotype ofmicroglia andmacrophages that impairs fibronectin aggregates maintainamixed activation t12-54B T. CD200-CD200r1 systeminmultiple sclerosis t12-61B M. Haaparanta-Solin,J.Rinne,L.Airas S. Vainio, A. M. Dickens,J.Tuisku, O.Eskola,Solin,D.Anthony, a focalEaE-model anti-vla-4 treatment reducesmicroglial activation in t12-60B N. Tentillier, M.Olesen,A.Etzerodt,S.Moestrup,Romero-Ramos J. Saura, T. inhibitory receptorCD200r1 Modulation ofneuroinflammation by themicroglial t12-58B N. Oliveira,A. R. Santiago,Paes-de-Carvalho,A.Ambrósio,J.Relvas R. Socodato,C. C. Portugal,T. Martins,T. Canedo, C.Silva,I.Domith, naling pathway pro- inflammatory signature viarock2/Csk/c-Src sig- Specific downregulation ofrhoatriggersmicroglia t12-57B S. Smolders,N.Swinnen,P. Legendre,J.- M. Rigo,B.Brône Valente, J.Serratosa,U.Perpiñá,Saura,C.Solà Valente, G.Dentesano,J.Serratosa,M. Pulido-Salgado,N.Rabaneda, C. Solà GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 119 studies in vivo and in vitro Vanmierlo, J. Bogie, S. Timmermans, K. Nelissen, K. Wouters, K. Wouters, K. Nelissen, J. Bogie, S. Timmermans, Vanmierlo, , D. Raj, N. Saiepour, D. Van Dam, N. Brouwer, B. Eggen, U.- K. Hanisch, B. Eggen, U.- Dam, N. Brouwer, D. Van , D. Raj, N. Saiepour, -amyloid plaque-associated microglia priming in microglia plaque-associated -amyloid trans genic mouse models of alzheimer’s disease alzheimer’s genic mouse models of trans Z. Yin De Deyn, E. Boddeke P. Bayer, Kamphuis, T. E. Hol, W. t12-69B β t12-68B ligand 3 (CCl3) in a mouse of CC chemokine role the — neuropathy diabetic M. Zychowska, E. Rojewska, A. Piotrowska, D. Pilat, J. Mika H. Zhang, S. Reiß, M. Jungblut, A. Bosio t12-67B of of the cytokine secretion profile Characterization astrocytes activated purified, highly t12-66B to the Interleukin-33 is synthesized in response and CnS injury to affect the response of microglia macrophages B. Wylot, K. Konarzewska, M. Zawadzka K. Wals, D. C. Anthony, B. G. Davis B. C. Anthony, D. K. Wals, t12-65B fluorescence imaging X-ray synchrotron Multiplexed metal using targeted heavy inflammation of brain nanoparticles N. Villacampa, B. Almolda, I. L. Campbell, B. González, B. Castellano L. Campbell, B. González, N. Villacampa, B. Almolda, I. t12-64B mice trEM2 in transgenic of Differential expression correlates or Il-10 production with CnS-targeted Il-6 after on neurodegeneration with opposing effects axotomy facial nerve E. Vegeto, A. M. Villa, G. Pepe, A. Maggi A. E. Vegeto, t12-63B and in male M2 polarization of microglia Induction using icv response to estrogens female mice and in injection of Il4 ,J. Vanmol T. N. Hellings, Stinissen, Gustafsson, K. Steffensen, P. A. J.- H. de Vries, J. Hendriks t12-62B neuroin- decreases deficiency beta X receptor liver sclerosis multiple model of animal in an mation flam 120 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon brain barrierdisruptioninducedby methamphetamine aquaporin 4isinvolved inbrain edemaandblood- t13-05B target forcytotoxic brain oedema? aquaporin 4inprimaryrat astrocytes — a therapeutic rapid tonicityinducedre-localisation ofendogenous t13-01B t S. J. Lee,H.Lim,Lee pathic pain microglia activation innerve injury-inducedneuro- Mechanisms ofsatellite glia-dependentspinalcord t12-70B M. McGahon,A.O’Neill,G.McGeown,T. Curtis flow autoregulation expressed inretinalastrocytes: implications forblood Mechanosensitive Piezo2channels arefunctionally t13-06B R. Leitão,C. A. Fontes-Ribeiro, P. Silva W. Du,J.Stern, supraoptic nucleus.ΔΔ regulates neurovascular couplinginthehypothalamic activity-dependent dendriticreleaseofneuropeptides t13-04B D. B. Dukefoss,Rosic,V. Jensen,A.Thoren,R.Enger, E. A. Nagelhus V. Malik,J.Klaus,S.Rajarathinam,I.Neumann,R.Rupprecht, the glia-vasculature interface tor GDf15inastrocytes andenhancetheirplasticityat antidepressants increaseexpressionofthetrophic fac- t13-02B R. Day, P. Kitchen,M.Salman,R.Bill,A.Conner, M.Conner spreading depression volume dynamics ofastroglial endfeetduringcortical t13-03B 13 n E urovaSCular I J. Filosa ntE ra CtI onS B. DiBenedetto GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 121 S. Barnett aIr S repair EP r Semenkovich, U. Suter F. anD on I rat Carr, A. Williams Carr, -positive progenitor cells form myelinationg myelinationg cells form progenitor -positive EGEnE α , T. 3 is required for the long-term maintenance of 3 is required for the long-term maintenance 14 r Dimas, L. Montani, J. A. Pereira, C. Dimas, L. Montani, J. Assinck, G. J. Duncan, J. R. Plemel, M. J. Lee, J. Liu, D. E. Bergles, W. Tetzlaff E. Bergles, W. Liu, D. J. Lee, J. Plemel, M. R. J. Duncan, J. Assinck, G. t14-02B - stem cell trans mesenchymal Human olfactory derived for Cn as a candidate plantation t14-03B wound after a cortical stab Dual effect of salubrinal injury in mice M. Ducommun, M. Granato t14-08B peripheral and function during cell dynamics Schwann regeneration nerve J. Dore, L. Patriarca, J. Volpe, A. McNally, J. Spinney A. McNally, J. Dore, L. Patriarca, J. Volpe, P. t14-06B acid synthesis in of endogenous fatty Essential role regeneration CnS myelin t14-05B by Precursor Cell function of oligodendrocyte Control their microenvironment E. Borger C. Benito Sastre, C. M. Davis, R. Mirsky, K. R. Jessen K. M. Davis, R. Mirsky, C. Benito Sastre, C. t14-07B between interactions a co-culture system to study and glial progenitors neurons pathetic sym t14-04B Stat cell phenotype in injured nerves the repair Schwann M. A. Barreda-Manso, N. Yanguas-Casás, M. Nieto-Sampedro, M. A. Barreda-Manso, N. Yanguas-Casás, M. L. Romero-Ramírez S. Lindsay, A. Toft, S. Johnstone, J. Griffin, J. Riddell, Toft, A. S. Lindsay, t14-01B PDGfr P. t oligodendrocytes and Schwann cells following contu- cells following and Schwann oligodendrocytes cord injury sion spinal 122 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon super-macroporous polymer scaffolds Bridging thegapinspinalcordinjuryusingnovel t14-11B S. Fazal,K.Bartus,M.Iberl,D.Wilton,E. J. Bradbury, R.Mirsky, K. R. Jessen regeneration potentialofDrGsensoryneurons activate c-Jun tocontrol theintrinsicgrowth state and Schwann cellsintheproximal stumpofinjurednerves t14-10B A. Faroni,Mobasseri,J.Gough,G.Terenghi, A.Reid scaffolds fornerve regeneration combined withsyntheticbiodegradable polymer Human Schwann-like adipose-derived stemcells t14-09B L. DeGroef L. Moons,I.Bollaerts,J.Van houcke,A.Beckers,K.Lemmens,I.Van Hove, era tive potentialintheaged zebrafish retina Microglial changes at thebaseofadiminished regen- t14-17B C. McClain,R.Franklin,B.Simons spinal cordremyelination Clonal oligodendrocyte progenitor celldynamics in t14-16B K. Magalon,J.Tracz, M.LeGrand,Moulis,P. Belenguer, M.Carre,P. Durbec H. K. Lee,L. S. Chaboub,W. Zhu,D.Zollinger,M. N. Rasband,S. the CnS signaling andtherapeutic targetforremyelination in Daam2-PIP5k isanovel regulatory pathway for wnt t14-13B A. Kalam,Rivera,Didangelos,E.Bradbury, A.Butt the role ofGSk3 t14-12B S. Hosseinzadeh,D.Wellings, M.Riehle,S.Barnett remyelination promotes oligodendrocyte maturation and Deciphering mechanisms by which olesoxime t14-15B B. Deneen β inregulating astrogliosis P. Fancy, GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 123 tion s Káradóttir T. Liou, S.- K. Shyue, Y.- S. Huang, K. Shyue, Y.- Liou, S.- Y. D. Fulton D. Parkinson P signalling in Schwann cell cell in Schwann P signalling Weng, D.- Weng, F. Moreno Flores T. M. Huang, C.- T. Mindos, X.- P. Dun, Mindos, X.- P. Liu, J. Tu, L. Wang Liu, J. Tu, nanoparticles for targeted delivery of sirna nanoparticles for targeted delivery Baumgärtner, T. Skripuletz, M. Stangel T. Baumgärtner, he P2X7 receptor is involved in normal re-myelina in normal involved he P2X7 receptor is ransduction of an immortalized olfactory ensheathing ensheathing olfactory an immortalized of ransduction , Yang Y. study an in vitro — cells astroglial reactive against t14-24B rna H. Cheng G. Begum, U. Ahmed, A. Stevens, t14-26B repair myelin to improve signalling aMPa Increasing R. M. Kovács, A. Denizot, H. Gautier, K. Volbracht, F. t14-25B of enhance the dopaminergic differentiation astrocytes bfGf repair through brain stem cells and promote J. Verheyen, J. Smith, S. Basilico, P. Guo, S. Pluchino J. Smith, S. Basilico, P. J. Verheyen, M.- J. Tsai, C.- J. Tsai, M.- following sciatic nerve injury nerve sciatic following t14-23B cells overexpressing olfactory ensheathing functional restoration synthase improves prostacyclin spinal cord rat to transected after transplantation t14-27B glutamate aMPa-type of regulation transcriptional lineage receptors in the oligodendrocyte t14-22B t Conte, E. Puccianti, Procacci, V. R. Smith, A. Faroni, S. Martin, P. Magnaghi, A. Verkhratsky L. Castelnovo, A. Reid, V. L. Salinas Tejedor, K. Jacobsen, G. Berner, V. Gudi, N. Jungwirth, F. Hansmann, Gudi, N. Jungwirth, F. V. Jacobsen, G. Berner, K. L. Salinas Tejedor, W. K. North, T. N. Plaza, J. Sierra, N. Plaza, J. Sierra, t14-18B t gene: (GfP) protein green fluorescent with the glia line capacity of its neuroregenerative evaluation devel opment and peripheral nerve repair nerve opment and peripheral devel t14-19B of Hippo/ya role the t14-20B stem of mesenchymal transplantation Intralesional cuprizone model demyelinating cells in the toxic 124 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon bit abluntedventilatory responsetoCo2 Inducible astrocyte specifickir4.1knockout miceexhi- t15-03B T. Deshpande,P. Bedner, C.Steinhäuser pling intheepileptichippocampus unravelling themechanisms causingastrocytic uncou- t15-02B M. Chisari,A.Scuderi, A. Sortino extensions by GPCrs Short-term modulation ofastrocyte plasmamembrane t15-01B t N. Sol-Foulon,S.Freeman, A.Desmazières,C.Lubetzki assembly prior to myelination intheCnS Molecular mechanisms underlying nodalprotein t15-09B A. Seidinger, A.Weise astrocytic pH-regulation incellcultureofmice t15-08B K. Rothenfusser, D.Boss,P. Jourdain,P. Magistretti,P. Marquet role ofcotransporters astrocyte swelling inresponsetoneural activation: t15-07B D. Reyes-Haro,E.Mora-Loyola,M. L. Martínez-Mendoza,A.Martínez-Torres functional expressionofGaBa t15-06B D. Huyghe,M.Terunuma, M.Pangalos,S.Moss g-aminobutyric typeBreceptors Glutamine synthetasestability isby regulated by t15-05B J. Heller, D.Rusakov receptors monitoredwithsuper-resolution microscopy Subcellular distributionandtrafficking ofastroglial t15-04B V. Hawkins,D.Mulkey neostriatum Er r tranSMIttEr 15 anD Ga P JunCtI ECEPtor onS ρ inastrocytes from S, I S, ElS on CHannElS GEnEral InforMatIon SCHEDulE PoStEr PrESEntatIon MaP, ovErvIEw, notES 125 Hugnot S tor C fa ourS uM 17 t 16 troPHIC Philips, E. Hughes, B. Morrison, Y. Lee, R. Sattler, D. Bergles, J. Rothstein Lee, R. Sattler, Philips, E. Hughes, B. Morrison, Y. t17-01B and devel- gliomas: characterization grade Diffuse low model for designing innovative opment of in vitro peutic approaches thera Rigau, H. Duffau, B. Rothhut, J. P. V. Lorcy, F. A. Genentier, S. Azar, t t16-02B support metabolic loss of oligodendrocyte age related T. M. Araujo, A. Spejo, R. Ferreira Jr, B. Barraviera, S. Kyrylenko, A. Oliveira B. Barraviera, S. Kyrylenko, M. Araujo, A. Spejo, R. Ferreira Jr, t t16-01B reaction and reduction of astroglial neuroprotection following stem cell engrafting human embryonic by avulsion root spinal cord ventral t15-13B for mouse lines of conditional knockout Generation opioid receptors in microglia A. Roeckel, D. Reiss, C. Gaveriaux-Ruff H. Maurin, L.- A. Gutierrez, N. Puente, G. Marsicano, P. Grandes P. A. Gutierrez, N. Puente, G. Marsicano, t15-12B mice expressing of mutant analysis anatomical of the in astrocytes receptors type-I cannabinoid hippocampus N. Zhao, F. Kirchhoff, W. Huang, A. Scheller Kirchhoff, W. N. Zhao, F. t15-11B subtypes Cav1.2 channels of l-type calcium role the in nG2 glia and Cav1.3 M. Velasco, G. Sheridan M. Velasco, t15-10B in is expressed Piezo1, ion channel, Mechanosensitive brain of the rat regions myelinated 126 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon and malignantperipheral nerve sheath tumour role oftherna t17-04B H. Duffau,K.Lamszus,B.Rothhut,J.- S. Guelfi, P.- O.Guichet,M. Teigell, L.Hoppe,N.Bakalara,Bauchet, like transdifferentiation ofglioblastomastemcells Molecular mechanisms ofnotch1-induced pericyte- t17-03B P. astrocytomas wHo-Grade IItoIv undergo drastic changes inpathological conditionslike aquaporin 4related orthogonalarrays ofparticles t17-02B , P. J. Tome Garcia, human Svzprogenitors andgliomas EGfr expressionconfersstem cell-like properties to t17-08B E. Huillard,M.Lathrop,Sanson,R.Houlston D. Figarella-Branger, C.Dehais,A.Idbaih,K.Mokhtari,J.- D. Zelenika,C.Wardell, M.Frampton,O.Saulnier, T. Pastinen,S.Hallout, Y. I. Simeonova,K.Labreche,A.Kamoun,V. Gleize,D.Chubb,E.Letouzé, oligodendrogliomas Identification ofagene mutated in7.5%ofanaplastic t17-07B B. Radlwimmer L. Silva,H.Becker, N.Kneisel,G.Poschet,I.Helbing,P. Lichter, R.Hell, J. Choi,B.Stradmann-Bellinghausen,N.Savaskan, macrophages differinglutamatergic geneexpressions glioblastoma cellsandtumor-associated microglia/ Human monocyte-derived macrophages exposedto t17-05B M. Palomo,Iruarrizaga-Lejarreta,Varela-Rey, A.Woodhoo monocarboxylate transporters inbrain tumorcells transport ofbranched-chain ketoacids ismediated by t17-06B Fallier-Becker, M.Hoffmeister, S.Mitrovic,Noell Riazalhosseini,S.Dobbins,N.Elarouci,F. Ducray, A.deReyniès, Erfani,P. Canoll,F. Doetsch, N.Tsankova -binding protein Hurinneurofibromas P. Hugnot A. Regnier-Vigouroux Y. Delattre, www.peprotech.com

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General Information Schedule Poster Presentation Ma p, Overview, Notes 131

otes ...... N ...... 132 MaP, ovErvIEw, notES PoStEr PrESEntatIon SCHEDulE GEnEral InforMatIon Program at aGlance tuesday, July 14 wednesday, July 15 thursday, July 16 friday, July 17 Saturday, July 18

09:00–10:00 Introductory Course p�20 Workshops p�21 Plenary Lecture P-02 p�26 Plenary Lecture P-04 p�32 Plenary Lecture P-06 p�38

10:15 symposia II S06–10 p�26 symposia Iv S16–20 p�32 symposia vI S26–30 p�38

12:15–13:00 Lunch Break Lunch Break Lunch Break

13:15 Poster session II p�86 Poster session I p�44 Poster session II p�86 14:00 Opening Plenary Lecture P-01 p�22 15:15 Plenary Lecture P-07 p�40 symposia I S01–05 p�22 symposia III S11–15 p�28 symposia v S21–25 p�35 16:00

17:15 Poster session I p�44 17:30–18:30 Plenary Lecture P-03 p�30 Plenary Lecture P-05 p�37

19:15–20:15 Informal Get-together with Drinks Call for Symposia

XIII European Meeting on Glial Cells in Health and Disease Edinburgh | July 8 – 11, 2017

Deadline for symposia proposals: March 28, 2016

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