Biotechnology in North Rhine-Westphalia Ekaterina Karpushenkova

1 Your investment location No. 1 in - North Rhine-Westphalia, July 7th, 2015 NRW – the economic powerhouse of Europe

More than 156 million consumers within a 500-kilometer radius NRW 2014 Area 34,110 km² Population 17.6 million Population density 515/km² GDP 624.7 bn € GDP per capita* 33,963 € Gainfully employed 9.1 m Private consumption* 346.2 bn € Exports 180.6 bn € Imports 206.7 bn € Foreign direct investments** 196.6 bn € *2013, **end of 2013

2 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 No. 61 Cluster policy: economic and cooperation structures

Industry (30%) Services (70%)

Trade and industry High tech

Research and development universities, institutes etc.

3 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 Future industries in NRW

• Automotive • Biotechnology • Chemicals • Energy • Environmental technology • Food • Health • Information and communications technology • Logistics • Mechanical engineering • Media • Microsystems technology and nanotechnology • New materials • Plastics

4 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 No. 85 Biotechnology in NRW

• With 400 life science companies, of which more than 100 belong to the biotechnology industry, NRW is one of Europe‘s leading biotech locations.

• The top international position of the state in biotechnology is demonstrated by its 9th place worldwide and its 1st place by a wide margin in Europe in terms of the number of biotech patent applications.

• Global players include QIAGEN in Hilden and Miltenyi Biotec in Bergisch-Gladbach.

• 27 universities and universities of applied sciences, numerous renowned research institutes, and initiatives such as BIO.NRW round off the quality of NRW as a biotechnology location.

5 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 No. 351 Leading biotech companies in NRW

• The environment for biotechnology companies in NRW is excellent:

• The region is home to numerous established chemical and pharmaceutical companies such as Bayer, Evonik Industries, Henkel, Janssen-Cilag, LANXESS and UCB. Their research departments provide the young biotechnology sector with a wide range of stimuli for new developments.

• As examples of global as well as small and medium-sized, dedicated biotechnology enterprises from NRW are portrayed above.

• A comprehensive overview of all life science and biotechnology companies in the state is provided at www.bio.nrw.de/firmendatenbank.

6 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 No. 351 NRW is a leading R&D location worldwide

The research network in NRW is one of the densest in Europe and provides ideal conditions for technology transfer

• 72 universities and technical colleges

• 50 special research areas at universities

• more than 50 non-university research facilities

• more than 60 technology centers

• 30 technology transfer units

7 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 No. 33 Research institutes in NRW

Research Center Jülich

German Aerospace Center, German Space Agency

German Centre for Neurodegenerative Diseases

center of advanced european studies and research (caesar)

13 Fraunhofer Institutes of Applied Research

12 Max-Planck Institutes

11 Institutes of the "Leibniz Association"

8 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 No. 359 Dense network of technology and start-up centers: biotechnology

BioCampus , Cologne; www.biocampuscologne.de As one of the major biotechnology parks in Germany, BioCampus Cologne on an area of over 254,000 m² is the future location for knowledge-based industry in the heart of Europe. Here, biotechnology companies find the right conditions to expand on their success: a prefinanced infrastructure and individual settlement concepts.

BioMedizinZentrum Dortmund (BMZ); www.bmz-do.de As a center of excellence for biotechnology and medical engineering the BioMedizinZentrum Dortmund is an ideal location on an area of 15,000 m² for young enterprises which want to be innovative and enjoy long-term success in these fields. It is regarded as the center of excellence of the Dortmund Technology Center and currently accommodates 29 companies.

BioZ Biotechnology Center Münster; www.technologiefoerderung-muenster.de The center was developed in close collaboration with biotech companies It currently provides three biotech companies with the possibility to conduct interdisciplinary research, with the center's proximity to outstanding research institutes such as the Max Planck Institute for Molecular Biomedicine or the Institute of Chemistry and Biosensors ICB being particularly advantageous.

Life Science Center, Düsseldorf; www.lsc-dus.de The Life Science Center Düsseldorf is an ultra-modern technology and start-up center offering innovative companies optimal surroundings for the realization and further development of their ideas.

9 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 SMEs – the backbone of the economy

99.5 % 79.2 % 82.3 %

• There are 755,000 small and medium-sized companies in NRW.

• They account for 99.5 % of all the companies in the state.

• They employ 79.2 % of all company employees subject to social insurance contributions.

• They provide 82.3 % of all training positions in NRW.

10 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 No. 27 Germany's no. 1 investment location

Volume of foreign direct investments in Germany 2013 (in EUR billion)

NRW 196,6

Hesse 113,5

Bavaria 105,7

Baden-Württemberg 81,0

Hamburg 65,8

Berlin 25,4

Lower Saxony 22,9

Source: Deutsche Bundesbank 5/2015, data: as of end of 2013

11 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 No. 25 Easy to reach – excellent transportation infrastructure

• 2 major international airports as well as 4 airports with European connections • More than 400 direct flights all over the world • Cologne/Bonn is Germany's no. 3 air cargo center

• 2,200 km of expressways – mostly with six lanes • 17,500 km of federal highways and country roads • Good access to European expressway system

• Highest rail network density in Germany • Important hub in high-speed rail network • Cologne: One of Europe's busiest railway junctions

• 720 km of waterways and around 120 ports • Access to North Sea, Baltic, Atlantic, Mediterranean, Black Sea • Duisburg is the world’s largest inland port

12 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 No. 315 NRW is no. 1 trade fair location worldwide

• With Cologne, Düsseldorf, Essen and Dortmund, NRW is the world's number one trade fair location.

• The state's outstanding infrastructure and central location in the heart of Europe ensure the excellent accessibility of all the trade fair cities and the transportation of the highlights from here to the world market.

• More than 60 internationally leading trade fairs take place in NRW. Biotech events: BIO.NRW.academy; BIO.NRW Work Platform BIO.NRW.red

• The trade fairs in NRW attract more than 6 million visitors every year.

13 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 No. 23 Biotech initiatives and platforms

• BIO.NRW Work Platform BIO.NRW.red; With the BIO.NRW.red work platform, BIO.NRW has established a permanent network of experts from a wide variety of fields in red biotechnology such as medicine, health and pharmaceuticals in NRW. Focal topics include the development of cell culture processes and active ingredients, biopharmaceutical process development and optimization, and the development of biomarkers for therapy and diagnostics.

• PerMediCon, Interdisciplinary congress with exhibition, Cologne; www.permedicon.de; meeting place of leading representatives from medicine, research, industry, politics and the regulatory field for discussing the progress and challenges of personalized medicine as well as its practical implications for healthcare. PerMediCon has thus established itself as a leading interdisciplinary communication platform for personalized medicine in Europe.

• Baesweiler BioTec Meeting; The Baesweiler BioTech meeting is an annual event that is initiated by the Baesweiler companies in the field biotechnology/life sciences and the International Technology and Service Center Baesweiler GmbH (its). It is very well received by industry, science and politics in both the Euroregion and throughout Germany.

• Biotech Iniciatives:

Bioanalytik Münster e.V., Münster;

BioCologne e.V., Cologne;

BioIndustry e.V., Bochum;

BioRiver – Life Science im Rheinland e.V., Düsseldorf;

Life-Tec -Jülich e.V., Aachen;

14 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 Information office of Ministry of Innovation, Science and Research of North Rhine-Westphalia

• Member of the German House of Science and Innovation

• Head office in Dusseldorf, foreign office only in Moscow

• Fields of expertise:  First information office for universities and science institutes both from Russia and NRW;  Marketing and promotion of NRW as leading region with focus on innovations;  Assistance by establishing contacts between universities and science institutes and coordination of bilateral projects;  Coordination of delegations from universities;  Information about supporting programs for joint bilateral and European projects

15 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 NRW.INVEST, Economic Development Agency – On the market for over 50 years

• 100-percent subsidiary of the state of North Rhine-Westphalia

• Head office in Düsseldorf, two subsidiaries, ten foreign branches

• 2 offices in Russia: Moscow and St. Petersburg

• Fields of expertise:  International location marketing  Direct acquisition in the target countries  Settlement consulting  Account management of foreign firms  Service for economic development in North Rhine-Westphalia

16 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015 Your contacts:

Information office of Ministry of Innovation, Science and Research / Representation office of Economic Development Agency of North Rhine-Westphalia NRW.INVEST Russia / Moscow Ekaterina Karpushenkova 1st Kasachi per. 7 119017 Moscow Phone.: +7 495 7301345 Fax: +7 495 2344951 E-Mail: [email protected] Internet: www.nrwinvest.com

NRW.INVEST Russia / St. Petersburg Tatiana Schwarzkopf Finlyandskiy avenue 4А 194044 St. Petersburg Phone: +7 812 3321501 Fax: +7 812 3321598 E-Mail: [email protected] Internet: nrwinvest.com

17 Your investment location No. 1 in Germany - North Rhine-Westphalia, July 7th, 2015