About EUROIMMUN

Medizinische Labordiagnostika EUROIMMUN AG

About EUROIMMUN

Autoimmune diagnostics Infectious serology Allergology

Antigen detection Molecular diagnostics Automation

2015

EUROIMMUN AG · 23560 Luebeck (Germany) · Seekamp 31 · Telephone +49 451 58550 · Fax 5855591 · E-mail [email protected] · Internet www.euroimmun.com EUROIMMUN is one of the leading manu- products. Every year, the EUROIMMUN facturers of medical laboratory diagnostics Academy receives almost 1000 customers worldwide and stands for innovation. Around from over 50 countries, providing training for 2000 employees in twelve countries develop, customers, fi eld staff, and employees from produce and sell test systems for the diagnosis all EUROIMMUN subsidiaries. The accredited of diseases, and software and automation Institute for Quality Assurance, an institution solutions for the performance and evaluation of the company, organises quality assess- of these assays. ment schemes and thus helps to maintain the high quality standard of external laboratories. Laboratories in over 150 countries use EUROIMMUN products for the diagnosis of The Institute for Experimental Immunology, autoimmune, infectious diseases and aller- another EUROIMMUN institution, is dedicated gies, and to perform genetic analyses. The to basic research. The institute also cooperates company was founded 1987 from the Uni- with universities, clinics and renowned versity of Luebeck (Schleswig-Holstein, Ger- research institutions from all over the world. many). In the business year 2014, the group These cooperations have resulted in a large turnover amounted to 175 million euros. number of diploma and doctorate theses. EUROIMMUN is ISO certifi ed (EN ISO 9001:2008, The enterprise has extensive expertise in EN ISO 13485:2012, ISO 13485/CMDCAS). the fi elds of immunology, cell biology, histo- logy, biochemistry and molecular biology. A large share of the company’s success can EUROIMMUN is based on state-of-the-art, be attributed to the associated reference labo- partly patented production processes and ratory, which offers a fast and differentiated microanalysis techniques. diagnosis to the EUROIMMUN customers and clarifi es several hundreds of patient samples Among the initial pioneer achievements of with diffi cult constellations every day. the company was the development of the BIOCHIP (1983). Today, EUROIMMUN has at EUROIMMUN meets its needs for qualifi ed its disposal virtually fully automated BIOCHIP personnel not only through its presence at fragmentation and production devices, which recruitment and trade fairs and advertisement, were designed and produced in-house and but also through its own training program. are now in use worldwide. Alongside the vocational school, the apprentices and trainees are offered a comprehen- Furthermore, EUROIMMUN commands a sive practical and theoretical program and broad technology base which has enabled intensive mentoring in the work routine. it to initiate and promote fundamental, new developments in medical laboratory diagnos- At present, the company employs 60 trainees tics. Examples are the molecular biological and around 2000 persons worldwide. Women synthesis of designer antigens, computer- represent nearly 60% of staff and thus the aided immunofl uores cence microscopy majority. 912 employees have an academic (CAIFM) and the development of multi-para- background, 134 of them hold a doctoral metric microarrays for the identifi cation of degree. genetic polymorphisms, tumours or pathogenic agents, amongst others. The atmosphere in the company is produc- tive and characterised by openness and Great expertise and ongoing training are mutual respect. EUROIMMUN offers unlim- essential for the use and distribution of the ited employment contracts. All employees

2 can participate in the company’s success as to participate in regular trainings. The com- shareholders, beneﬁ t from the company’s pany’s restaurant offers an excellent choice pension scheme, receive bonuses for excel- of food. Day care and an after-school club is lent performance, and have the possibility provided for the employees’ children.

EUROIMMUN in ﬁ gures

1987 founded in Luebeck, Germany 7 ofﬁ ces in Germany 175 M euros annual Group turnover in 2014 12 subsidiaries in other countries 1998 employees worldwide 176 proprietary/in-licensed IP rights 912 university graduates 3rd place “Most Innovative Medium- 134 employees with doctoral degree Sized Businesses in Germany“ 60 apprentices (WirtschaftsWoche, April 2014)

Recent product innovations

Anti-PLA2R ELISA: Quantitative detection of autoantibodies against phospholipase A2 recep-

tor (PLA2R) in primary membranous glomerulonephritis (MGN) Anti-Echinococcus ELISA: Semiquantitative diagnosis of infections with Echinococcus granulosus as well as Echinococcus multilocularis by the use of native, purifi ed Echinococcus multilocularis vesicular fl uid (EmVF) CXCL13 ELISA: Diagnosis and therapy monitoring of neuroborreliosis. First assay worldwide for the quantifi cation of CXCL13 in cerebrospinal liquid to be approved for in vitro diagnostics DPA-Dx Profi les Pollen, Insect Venoms, Paediatrics: Molecular allergy diagnostics based on individually purifi ed allergen components (defi ned partial allergens, DPA) for differential diagnosis of allergic sensitisation patterns EUROArray HPV: Molecular diagnosis of infections for detection and typing of 30 anogenital HPV types (18 high-risk and 12 low-risk HPV) in a single reaction EUROPattern Microscope and software: Automated microscopy and modern interpretation of diagnostic results at the PC screen (ANA, ANCA, Crithidia, tissue, EUROPLUS – also in mosaics) and pattern recognition with titer determination Dengue Virus NS1 ELISA: Detection of viral protein NS1 as early marker of an acute infection. Reliable diagnosis in all stages of the disease, exclusion of cross reactions with anti-fl avivirus antibodies and differential diagnosis of tropical diseases EUROBlotOne: Complete automation solution for the immunoblot workstation – from sample pipetting to the fi nal result

3 Publications with EUROIMMUN’s participation ( 2015)

Publications and recent developments in serological detection. Front Immunol 11(6): 221 (2015). 1. Diecker J, Schlumberger W, McHugh N, Hamann P, Vlag van der J, Berden JH. Reactivity in ELISA 10. Michaels MA, Jendrek ST, Korf T, Nitzsche T, with DNA-loaded nucleosomes in patients with Teegen B, Komorowski L, Derer S, Schröder T, proliferative lupus nephritis. Mol Immunol 68: 20- Baer F, Lehnert H, Büning J, Fellerman K, Sina C. 24 (2015). Pancreatic autoantibodies against CUZD1 and GP2 are associated with distinct clinical phenotypes of 2. Gerlach S, Affeldt K, Pototzki L, Krause C, Voigt Crohn’s Disease. Inflamm Bowel Dis [Epub] (2015). J, Fraune J, Fechner K. Automated evaluation of Crithidia luciliae based indirect immunofluorescence 11. Müller MA, Meyer B, Corman VM, Al-Masri M, tests: A novel application of the EUROPattern-Suite Turkestani A, Ritz D, Sieberg A, Aldabbagh S, Bosch technology. J Immunol Res Article ID 742402 [Epub] B-J, Lattwein E, Alhakeem RF, Assiri AM, Albarrak (2015). AM, Al-Shangiti AM, Al-Tawfiq JA. Wikramaratna P, Alrabeeah AA, Drosten C, Memish ZA. Presence 3. Gosink J. Parathyroid hormone, calcitonin and of Middle East respiratory syndrome coronavirus vitamin D testing in calcium and bone metabolic antibodies in Saudi Arabia: a nationwide, cross- disorders. Medlab Magazine 2 (2015). sectional, serological study. Lancet Infect Dis 15(5): 559-564 (2015). 4. Gutiérrez C, Tejedor-Junco MT, González M, Lattwein E, Renneker S. Presence of antibodies 12. Muth D, Corman VM, Meyer B, Assiri A, Al-Masri but no evidence for circulation of MERS-CoV in M, Farah M, Steinhagen K, Lattwein E, Al-Tawfiq dromedaries on the Canary Islands, 2015. Euro JA, Albarrak A, Müller MA, Drosten C, Memish Surveill 20(37): pii=30019 (2015). ZA. Infectious MERS-Coronavirus excretion and serotype variability based on live virus isolates 5. Jarius S, Wildemann B, Stöcker W, Moser A, from patients in Saudi Arabia. J Clin Microbiol pii: Wandinger KP. Psychotic syndrome associated with JCM.01368-15 [Epub] (2015). anti-Ca/ARHGAP26 and voltage-gated potassium channel antibodies. J Neuroimmunol doi: 10.1016/j. 13. Papp M, Sipeki N, Tornai T, Altorjay I, Norman GL, jneuroim.2015.07.009. [Epub] (2015). Shums Z, Roggenbuck D, Fechner K, Stöcker W, Antal-Szalmas P, Veres G, Lakatos PL. Rediscovery 6. Krause C, Ens K, Fechner K, Voigt J, Fraune J, of the anti-pancreatic antibodies and evaluation of Rohwäder E, Hahn M, Danckwardt M, Feirer C, Barth their prognostic value in a prospective clinical cohort E, Martinetz T, Stoecker W. EUROPattern-Suite of Crohn's patients: the importance of specific target technology for computer-aided immunofluorescence antigens (GP2 and CUZD1). J Crohns Colitis 9(8): microscopy in autoantibody diagnostics. Lupus 24: 659-68 (2015). 516-529 (2015). 14. Pavlidis P, Komorowski L, Teegen B, Liaskos C, 7. Langenhan J, Mersmann M, Dworschak J, Schmidt Koutsoumpas AL, Smyk DS, Perricone C, Mytilinaiou E, Probst C, Stöcker W. Track Z (FS): Novel MG, Stöcker W, Forbes A, Bogdanos DP. Diagnostic developments in the diagnosis and treatment of and clinical significance of Crohn’s disease-specific autoimmune blistering diseases. Biomed Tech (Berl.) pancreatic anti-GP2 and anti-CUZD1 antibodies. doi: 10.1515/bmt-2015-5018 (2015) Clin Chem Lab Med doi: 10.1515/cclm-2015-0376. [Epub] (2015). 8. Lemcke S, Sokolowski S, Rieckhoff N, Buschtez M, Kaffka C, Winter-Keil A, Schaller C, Rottmann N, Sadik 15. Piepgras J, Höltje M, Michel K, Li Qin, Otto C, CD, Stöcker W, Zilikens D, Schmidt E. Automated Drenckhahn C, Probst C, Schemann M, Jarius direct immunofluorescence analyses of skin biopsies. S, Stöcker W, Balint B, Meinck H-M, Buchert R, J Cutan Pathol doi: 10.1111/cup.12637 [Epub] (2015). Dalmau J, Ahnert-Hilger G, Ruprecht K. Anti-DPPX encephalitis: pathogenic effects of antibodies on gut 9. Mastroianni-Kirsztajn G, Hornig N, Schlumberger W. and brain neurons. Neurology 85(10): 890-897 (2015). Autoantibodies in renal disease – clinical significance

4 16. Probst C, Komorowski L, Graaff de E, Coevorden- in preclinical Alzheimer’s disease during middle age. Hameete van M, Rogemond V, Honnorat J, JAMA Neurol 72(9):1029-42 (2015). Sabeter L, Graus F, Jarius S, Voltz R, Wildemann B, Franciotta D, Blöcker IM, Schlumberger W, Stöcker 24. Zerche M, Weissenborn K, Ott C, Dere E, Asif AR, W, Sillevis Smitt PAE. Standardized test for anti-tr/ Worthmann H, Hassouna I, Rentzsch K, Tryc AB, DNER in patients with paraneoplastic cerebellar Dahm L, Steiner J, Binder L, Wiltfang J, Sirén degeneration. Neurol Neuroimmunol Neuroinflamm A, Stöcker W, Ehrenreich H. Pre-existing serum 2(2):e68 (2015). autoantibodies against the NMDAR subunit NR1 modulate evolution of lesion size in acute ischemic 17. Rohwäder E, Locke M, Fraune J, Fechner K. stroke. Stroke 46(5):1180-1186 (2015). Diagnostic profile on the IFA 40: HEp-20-10 – an immunofluorescence test for reliable antinuclear antibody screening. Expert Rev Mol Diagn 15(4):451- 62 (2015). Scientific presentations 18. Reichert S, Schlumberger W, Dähnrich C, Hornig N, Altermann W, Schaller HG, Schulz S. Association 1. Brix B, Vanderstichele H. Use of Beta-Amyloid 1-42/1- th of levels of antibodies against citrullinated cyclic 40 Ratio in routine diagnostic labs. 11 International peptides and citrullinated α-enolase in chronic Conference on Alzheimer’s and Parkinson’s Disease, and aggressive periodontitis as a risk factor of Nice, France (2015). rheumatoid arthritis: a case control study. J Trans 2. Cavalar M, Harder M, Hellberg L, Opelka P, Götzl J, Med 132(83):1-10 (2015). Steller U. HPV detection and typing by molecular 19. Scharf M, Miske R, Heidenreich F, Giess R, Landwehr diagnostic microarray. EUROGIN, Sevilla, Spain P, Blöcker M, Begemann N, Denno Y, Tiede S, (2015). Dähnrich C, Schlumberger W, Unger M, Teegen 3. Dähnrich C, van Beek N, Hornig N, Goletz S, B, Stöcker W, Probst C, Komorowski L. Neuronal Dworschak J, Schlumberger W, Zillikens D, Schmidt Na(+)/K(+) ATPase is an autoantibody target in E. Multivarianter Profil-ELISA zur sensitiven paraneoplastic neurological syndrome. Neurology und spezifischen Einschrittdiagnostik bullöser 84(16): 1673-1679 (2015). Autoimmundermatosen. 48th DDG meeting, Berlin, 20. Schlumberger W. Autoantibody diagnostics in Germany (2015). autoimmune mephropathies. Medlab Magazine 2 4. Edmonson DG, Witt B, Probst C, Schlumberger (2015). W, Stöcker W, Norris SJ, Komorowski L. Passive 21. Seitz-Polski B, Dolla G, Payré C, Tomas NM, immunization using polyclonal or monoclonal anti- Lochouarn M, Jeammet L, Mariat C, Krummel T, dimeric OspC antibodies prevents infection with th Burtey S, Courivaud C, Schlumberger W, Zorzi K, Borrelia burgdorferi B31 in mice. 14 ICLB, Vienna, Benzaken S, Bernard G, Esnault VL, Lambeau G. Austria (2015). Cross-reactivity on anti-PLA2R1 autoantibodies 5. Gerlach S, Affeldt K, Pototzki L, Krause C, Voigt to rabbit and mouse PLA2R1 antigens and J, Fraune J, Stöcker W, Fechner K. Automated development of two novel ELISAs with different evaluation of Crithidia luciliae IFT as novel diagnostic performances in idiopathic membranous application of the “EUROPattern-Suite”. 12th nephropathy. Biochimie pii: S0300-9084(15)00254-0. Dresden Symposium on Autoantibodies, Dresden, doi: 10.1016/j.biochi.2015.08.007. [Epub] (2015). Germany (2015). 22. Stoeck K, Carstens P-O, Jarius S, Raddatz D, Stöcker 6. Gerlach S, Hochstrate N, Affeldt K, Viertel V, W, Wildemann B, Schmidt J. Prednisolone and Krause C, Voigt J, Fraune J, Stöcker W, Fechner K. azathioprine are effective in DPPX antibody-positive Automated immunofluorescence microscopy for autoimmune encephalitis with glucocorticosteroids instant screening and confirmation of ANCA. 12th and azathioprine. Neurol Neuroimmunol Neuro- Dresden Symposium on Autoantibodies, Dresden, inflamm 2(3):e86 (2015). Germany (2015). 23. Sutphen CL, Jasielec MS, Shah AR, Macy EM, 7. Kaden J, Herbst V, Block M, Scherberich J, Abendroth Xiong C, Vlassenko AG, Benzinger TLS, Stoops EEJ, D, Nockher A, Schlumberger W. Uromodulin serum Vanderstichele HMJ, Brix B, Darby HA, Vandijck MLJ, levels in kidney graft donors and recipients. 24th Ladenson JH, Morris JC, Holtzman DM, Fagan AM. Annual Meeting of the German Transplantation Longitudinal cerebrospinal fluid biomarker changes Society, Dresden, Germany (2015).

5 1. Komorowski L, Scharf M, Teegen B, Rentzsch 10. Schlumberger W. Novel markers in autoimmunity: K, Schlumberger W, Stöcker W. Autoantibodies Kidney and neurological diseases. 40th Arab Health against tubular basement membrane in progressive Congress / Medlab, Dubai, United Arab Emirates. systemic sclerosis are directed against Scl-70. 12th Dresden Symposium on Autoantibodies, Dresden, 11. Schlumberger W. Autoantibodies against Germany (2015). phospholipase-A2 receptors in membranous nephropathy. Seminar, Unità Operativa Complessa 2. Miske R, Rosenkranz T, Müller M, Hahn S, Blöcker IM, di Nefrologia, Università Cattolica, Italy (2015). Mindorf S, Denno Y, Schlumberger W, Stöcker W, Probst C, Terborg C, Komorowski L. Autoantibodies 12. Stöcker W. Comprehensive diagnostics of neurology- against glutamate receptor delta2 in a Caucasian related autoantibodies using authentic recombinant patient after allogenic stem cell transplantation. 1st autoantigens. All-Russia XX Conference on Congress of the European Academy of Neurology, Neuroimmunolgy, Multiple Sclerosis, St. Petersburg, EAN, Berlin, Germany (2015). Russia (2015).

3. Miske R, Melzer N, Scharf M, Wiendl H, Meuth S, 13. Stöcker W. Discovery of new target antigens in Synofzik M, Dettmann IM, Mindorf S, Denno Y, Teegen autoimmune encephalitis applying histoimmune B, Stöcker W, Brakopp S, Probst C, Komorowski L. precipitation. EUROIMMUN Autoimmunity Tripartite Neurochondrin is a target for autoantibodies in a Forum 2015 (Tripartite: Clinic, Laboratory, and unique form of autoimmune cerebellitis associated EUROIMMUN), Beijing, China (2015). with brainstem syndrome. 12th Dresden Symposium 14. Stöcker W. Revealing new forms of autoimmune on Autoantibodies, Dresden, Germany (2015). encephalitis associated with autoantibodies 4. Seismann H, Bantleon F, Wolf S, Weimann A, Suer against neuron specific Na/K-ATPase ATP1A3, W, Jakob T, Bilo B, Spillner E. Component resolution neurochondrin, flotillin and inositoltriphosphat- for improved diagostics of hymenoptera venom receptors. Oral presentation at the Beijing Union allergy using a set of recombinant vespula and Medical College Hospital, Beijing, China (2015). polistes venom allergens. European Academy of 15. Stöcker W. Discovery of new target antigens in Allergy and Clinical Immunology Congress 2015, autoimmune encephalitis applying histoimmune EAACI, Barcelona, Spain (2015). precipitation. 12th Dresden Symposium on 5. Stöcker W, Probst C, Teegen B, Rentzsch K, Autoantibodies, Dresden, Germany (2015). Schlumberger W, Fraune J, Komorowski L. Multiparameter autoantibody screening in the diagnosis of neurological autoimmune diseases. 1st Congress of the European Academy of Neurology, EAN, Berlin, Germany (2015).

6. Ullmann AJ, Brandt KS, Zachary PW, Dolan MC, Gilmore R, Witt B, Stöcker W, Schlumberger W, Probst C, Komorowski L. N-terminally disulfide- bridged dimeric OspC is a promising candidate for a practical Lyme vaccine. 14th ICLB, Vienna, Austria (2015).

7. Heick SB. Cutting-edge molecular diagnostics of genetic and infectious diseases. 8th International & 13th National Congress on Quality Improvement in Clinical Laboratories, Tehran, Iran (2015).

8. Komorowski L. Neurochondrin is a target for autoantibodies in a unique form of autoimmune cerebellitis associated with brainstem syndrome. 12th Dresden Symposium on Autoantibodies, Dresden, Germany (2015).

9. Schlumberger W. Algorithm of coeliac disease investigation. 40th Arab Health Congress / Medlab, Dubai, United Arab Emirates (2015).

6 New patents

1. Meyer W, Scheper T, Kaffka R. Device and method for storing and transporting a bodily fluid. German and International patent application DE 10 2013 008 468.7 (filded 2013) and WO 2014/173657 (filed 2014).

2. Scheper T, Meyer W, Langner J. Device and method for the diagnosis of nasopharyngeal carcinoma. German and International patent application DE 10 2013 001 699.1 (filed 2013) and WO 2014/118151 (filed 2014).

3. Stöcker W, Rottmann N. Method and analysis device for microscopic examination of a tissue section or cell smear. German and International patent application DE 10 2012 013 678 (filed 2012) and WO2014/009066 (filed 2013).

4. Stöcker W, Rottmann N. Device and method for incubating patient samples. German and International patent application DE 10 2012 013 680 (filed 2012) and WO 2014/009067 (filed 2013).

5. EUROIMMUN China. Vorrichtung zur biologischen Detektion (Device for biological detection). German utility patent application DE 20 2015 001 876 (filed 2015).

6. EUROIMMUN China. Western Blot-Analysiervorrichtung (Western blot analysing device). German utility patent application DE 20 2015 001 878 (filed 2015).

7. Feirer C, Pannhoff H. Calibration standard for a device for image-based representation of biological material. German and International patent application DE 10 2013 021 097 (filed 2013) and WO 2015/90534 (filed 2014).

8. Hüttmann G, Morrin M, Spahr H. Method for creating an image of an object, and optical apparatus. German and International patent application DE 10 2014 002 584 (filed 2014) and WO 2015/110250 (filed 2015).

9. Rottmann N, Stöcker W. Method and analysis device for microscopic examination of a tissue section or cell smear. European and US patent application EP 2 872 254 (filed 2013) and US 2015/211964 (filed 2013).

10. Rottmann N, Stöcker W. Transparent object holder with labelling. European and Internatio- nal patent application EP 2 896 458 (filed 2014) and WO 2015/106774 (filed 2014).

11. Stöcker W. Improved device and method for reactions between a solid and a liquid pha- se. German and International patent application DE 10 2014 001 481 (filed 2014) and WO 2015/62715 (filed 2014).

7 EUROIMMUN Polska Sp. z.o.o. EUROIMMUN Med. Diagnostics Özmen Tıbbi Laboratuar Barbara Łobos Canada Inc. Teşhisleri A. Ş. ul. Widna 2a Dr. Donglai Ma EUROIMMUN TÜRKIYE 50-543 Wrocław Unit 36 Kadriye Vogt & Peter Vogt POLAND 1100 Central Parkway West Levent mah. Hardal Sokak No: 4 Tel.: +48 71 3730808 Mississauga, ON L5C 4E5 Beşiktaş Fax: +48 71 3730011 CANADA 34330 Istanbul E-mail: [email protected] Tel.: +1 905 8961504 TURKEY Fax: +1 905 8961506 Tel.: +90 212 3258504 EUROIMMUN Italia s.r.l E-mail: [email protected] Fax: +90 212 3258506 Dr. Fabio Valenti E-mail: [email protected] Corso Stati Uniti 4 – Scala F EUROIMMUN (South East Asia) 35127 Padova Pte. Ltd. EUROIMMUN Brasil Ltda. ITALY Li Chuan Gustavo Janaudis Tel.: +39 049 7800178 No.1 Changi Business Park R. José Gonçalves Galeão, 198 Fax: +39 049 7808103 Avenue 1, #01-01/05 São Paulo, SP E-mail: [email protected] Singapore 486058 03227-150 SINGAPORE BRAZIL EUROIMMUN UK Ltd. Tel.: +65 65425638 Tel.: +55 11 2305-0170 Dr. Daniel Agustus Fax: +65 65425648 E-mail: [email protected] Ashville House E-mail: [email protected] 131-139 The Broadway EUROIMMUN South Africa Pty Ltd. Wimbledon EUROIMMUN US Inc. Claudia Ohst SW19 1QJ London Hamid Erfanian 39 Clifton Crescent UNITED KINGDOM 1 Bloomﬁ eld Avenue Parklands, 7441 – Cape Town Tel.: +44 20 85407058 Mountain Lakes, NJ 07046 SOUTH AFRICA E-mail: [email protected] USA Tel.: +27 21 5577666 Tel.: +1 8009132022 Fax: +27 21 5577666 EUROIMMUN Medical Diagnostics Fax: +1 9736561098 E-mail: [email protected] (China) Co., Ltd. E-mail: [email protected] Prof. Dr. Wang Jing & Li Chuan EUROIMMUN France SAS Rm. 1908-1910, Building No. 1, EUROIMMUN Schweiz AG Claude Audiberti No. 8 Beichen East Road, Hansruedi Steffen Espace Villa Parc – L’Erable Chaoyang District Hirschmattstr. 1 1, Avenue Marne et Gondoire 100101 Beijing, P.R.C. 6003 Lucerne 77600 Bussy-Saint-Martin CHINA SWITZERLAND FRANCE Tel.: +86 10 58045000 Tel.: +41 41 3609000 Tel.: +33 164616666 Fax: +86 10 58045001 Fax: +41 41 3609020 Fax: +33 164616220 E-mail: [email protected] E-mail: [email protected] E-mail: [email protected]

EUROIMMUN Germany 2 Groß Groenau 5 Rennersdorf Am Sonnenberg 9 OT Rennersdorf, Im Kreppel 1 2 3 23627 Groß Groenau 02747 Herrnhut 1 4 Tel.: +49 451 5855-0 Tel.: +49 35874 222-0 Fax: +49 451 5855-591 Fax: +49 35874 222-31034 E-mail: [email protected] E-mail: [email protected]

5 3 Dassow 6 Bernstadt 6 Werkstraße 2-22 Am Pließnitztal 1 23942 Dassow 02748 Bernstadt 7 Tel.: +49 38826 8999-41101 Tel.: +49 35874 222-0 Fax: +49 38826 8999-41109 Fax: +49 35874 222-31034 E-mail: [email protected] E-mail: [email protected]

1 Headquarters Luebeck 4 Selmsdorf 7 Pegnitz Seekamp 31 An der Trave 1 Schloßstraße 11 23560 Luebeck 23923 Selmsdorf 91257 Pegnitz Tel.: +49 451 5855-0 Tel.: +49 451 6936-0 Tel.: +49 9241 48979-0 Fax: +49 451 5855-591 Fax: +49 451 6936-38999 Fax: +49 9241 48979-134 E-mail: [email protected] E-mail: [email protected] E-mail: [email protected]

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