Long-Term Pantethine Treatment Counteracts Pathologic Gene
Long-Term Pantethine Treatment Counteracts Pathologic Gene Dysregulation and Decreases Alzheimer’s Disease Pathogenesis in a Transgenic Mouse Model Kévin Baranger, Manuel van Gijsel-Bonnello, Delphine Stephan, Wassila Carpentier, Santiago Rivera, Michel Khrestchatisky, Bouchra Gharib, Max de Reggi, Philippe Benech To cite this version: Kévin Baranger, Manuel van Gijsel-Bonnello, Delphine Stephan, Wassila Carpentier, Santiago Rivera, et al.. Long-Term Pantethine Treatment Counteracts Pathologic Gene Dysregulation and Decreases Alzheimer’s Disease Pathogenesis in a Transgenic Mouse Model. Neurotherapeutics, Springer Verlag, 2019, 10.1007/s13311-019-00754-z. hal-02339537 HAL Id: hal-02339537 https://hal.archives-ouvertes.fr/hal-02339537 Submitted on 12 Nov 2019 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Long-term pantethine treatment counteracts pathologic gene dysregulation and decreases Alzheimer’s disease pathogenesis in a transgenic mouse model. Baranger Kévin*, van Gijsel-Bonnello Manuel*,a, Stephan Delphine, Carpentier Wassila†, Rivera Santiago, Khrestchatisky Michel, Gharib Bouchra, De Reggi Max# and Benech Philippe#,b Aix-Marseille Univ, CNRS, INP, Inst Neurophysiopathol, Marseille, France. † Sorbonne Universités, UPMC Univ Paris 06, Inserm, UMS Omique, Plateforme Post- génomique de la Pitié-Salpêtrière (P3S), F-75013, Paris, France.
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