Geom mean Geom mean Ratio of geom Parametric p- of intensities of intensities FDR means Description value in class 1 in class 2 Pla/Bag 238 (Plate) (Bag) coagulation factor XIII, A1 206 0,0005558 0,1940962 1313,3 29,7 44,219 polypeptide

interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation 0,0017883 0,2490398 1535,5 81,1 18,933 factor 2, p40)

Immunoglobuli 0,0063804 0,3394787 3050,5 258,7 11,792 n epsilon chain

interferon, alpha-inducible 11 4,62E-05 0,1541482 347,2 33,4 10,395 protein 27 0,0035346 0,3039332 226,8 22 10,309 astrotactin 2 deoxyribonucle 0,0040473 0,3148984 1155,1 125 9,241 ase I-like 3 0,0010495 0,2205294 213,2 24,1 8,846 follistatin

galectin- 0,0315078 0,4885675 644,8 76,2 8,462 related protein androgen- 0,0013899 0,238971 287 35,4 8,107 induced 1

A kinase (PRKA) anchor protein (gravin) 236 1,06E-05 0,115911 2061,4 256,7 8,03 12

tumor necrosis factor receptor superfamily, member 11a, 0,002746 0,2846759 405 50,5 8,02 NFKB activator

lipoma HMGIC 248 0,0008375 0,2147006 240,6 32,3 7,449 fusion partner glutathione S- transferase 0,0183462 0,4368809 557,1 80,1 6,955 theta 1 solute carrier family 18 (vesicular monoamine), 122 3,94E-05 0,1541482 121,5 17,6 6,903 member 2 signal transducing adaptor family 233 6,27E-05 0,1541482 354,3 51,6 6,866 member 1 Transcribed 0,0050276 0,3240923 140,3 20,6 6,811 locus aldehyde dehydrogenas e 5 family, member A1 (succinate- semialdehyde dehydrogenas 0,0294865 0,4819829 236,6 38,2 6,194 e) guanylate cyclase activator 1A 0,0074099 0,3504479 339,1 55 6,165 (retina) 0,0028748 0,288618 160,9 27,3 5,894 astrotactin 2 cadherin 1, type 1, E- cadherin 0,0474256 0,521195 164,4 27,9 5,892 (epithelial) Hypothetical gene supported by 32 0,0001602 0,1541482 131 22,7 5,771 BC008048 chemokine (C- C motif) ligand 0,0310777 0,487288 855,2 156,3 5,472 26 solute carrier family 18 (vesicular monoamine), 211 0,0004192 0,1940962 87,5 16,2 5,401 member 2 cornichon homolog 3 0,0239715 0,4638862 184,6 34,4 5,366 (Drosophila) solute carrier family 47, 0,0281004 0,4758739 416,2 78,3 5,315 member 1 phospholipase 0,0437213 0,5141825 389,1 74,3 5,237 A2, group V

A kinase (PRKA) anchor protein (gravin) 80 0,0010055 0,2205294 349,2 66,8 5,228 12

cytochrome P450, family 7, subfamily B, 0,006242 0,3373399 96,9 18,6 5,21 polypeptide 1 NK3 0,0014765 0,2418041 179,5 34,7 5,173 homeobox 1

0,0396349 0,5083518 1364 264,1 5,165 CD1b molecule receptor (G protein- coupled) activity modifying 0,0032019 0,2999829 1881,5 367,3 5,123 protein 1 Primary neuroblastoma cDNA, clone:Nbla036 14, full insert 0,0079462 0,3545654 320,5 62,8 5,104 sequence CDNA clone IMAGE:525927 0,0495077 0,5248641 98 19,5 5,026 2

24- dehydrocholest 0,0205742 0,4485902 249,5 50 4,99 erol reductase 84 0,0008316 0,2144704 812,7 163 4,986 mucolipin 2 retinoic acid receptor responder (tazarotene 0,0421942 0,5127624 520,8 105,9 4,918 induced) 1

sphingosine-1- phosphate 71 6,66E-05 0,1541482 410,3 83,9 4,89 phosphotase 2 scavenger receptor class 0,0050935 0,3253354 643,3 131,8 4,881 B, member 1 signaling lymphocytic activation molecule family member 0,0149731 0,4142987 1953,1 401,4 4,866 1

tight junction protein 1 (zona 0,0073091 0,3490175 66,7 13,8 4,833 occludens 1) chemokine (C- C motif) ligand 0,018084 0,4355503 298,8 62,6 4,773 13 chemokine (C- C motif) ligand 153 0,000125 0,1541482 502,8 106,6 4,717 24 T-cell lymphoma invasion and 150 0,0001568 0,1541482 633,5 138 4,591 metastasis 2 protein kinase (cAMP- dependent, catalytic) 0,0141052 0,4075754 84 18,4 4,565 inhibitor beta scavenger receptor class 0,0062598 0,3373399 294 64,5 4,558 B, member 1

tetratricopeptid e repeat, ankyrin repeat and coiled-coil 0,0039924 0,3136271 63,2 13,9 4,547 containing 1

carboxypeptida se, vitellogenic- 0,0285783 0,4776731 1087,6 239,5 4,541 like fermitin family homolog 2 0,0022605 0,2690842 136,5 30,1 4,535 (Drosophila)

0,0416725 0,5120746 1037,8 229 4,532 CD1c molecule 0,011718 0,3891601 1346,3 297,5 4,525 cathepsin C 274 9,00E-06 0,115911 542,3 120 4,519 follistatin

Transcribed locus, strongly similar to XP_001102524 .1 PREDICTED: similar to Olfactory receptor 2I1 [Macaca 119 8,85E-05 0,1541482 153,1 33,9 4,516 mulatta]

sphingosine-1- phosphate 0,0062873 0,3375417 652,1 145,9 4,469 phosphotase 2 Lipoma HMGIC fusion 0,0013062 0,2351565 219,2 49,1 4,464 partner collagen, type 2 0,0010016 0,2205294 320,4 72,3 4,432 VI, alpha 1 lymphocyte 0,0067543 0,3434229 471,8 106,6 4,426 antigen 9 N- acylsphingosin e amidohydrolas e (acid ceramidase)- 263 0,000473 0,1940962 429,4 97,3 4,413 like signal transducing adaptor family 117 0,000103 0,1541482 170,2 38,9 4,375 member 1 N- acylsphingosin e amidohydrolas e (acid ceramidase)- 116 0,0001433 0,1541482 615,1 141,6 4,344 like glycine amidinotransfe rase (L- arginine:glycin e amidinotransfe 0,0280974 0,4758739 275,4 63,4 4,344 rase) phospholipase A2, group VII (platelet- activating factor acetylhydrolas 0,0180192 0,4353512 1789,3 412,5 4,338 e, plasma) angiotensin I converting enzyme (peptidyl- dipeptidase A) 0,0175825 0,4322644 434,3 100,4 4,326 1 C-type lectin- 31 0,0001711 0,1541482 280 65 4,308 like 1

MRNA; cDNA DKFZp547N07 4 (from clone DKFZp547N07 0,003848 0,3114214 492,3 116,7 4,219 4) STAM binding 0,019092 0,4414157 657,4 158,7 4,142 protein-like 1 tubulin, beta 0,0057809 0,3304939 1902 460,5 4,13 2A

oligonucleotide /oligosaccharid e-binding fold 0,0020139 0,2572019 2160,3 524,4 4,12 containing 2A Transcribed 0,0048751 0,3211399 1002,5 247,8 4,046 locus

232 7,72E-05 0,1541482 151,3 38 3,982 paraoxonase 2 pleckstrin homology domain containing, family A 115 0,0001465 0,1541482 78,8 20 3,94 member 5

coiled-coil- helix-coiled-coil- helix domain 214 0,0003296 0,1766753 1278,7 327,1 3,909 containing 7 glycoprotein, alpha- galactosyltrans ferase 1 /// similar to glycoprotein galactosyltrans ferase alpha 1, 0,0124535 0,3960995 1533,8 392,9 3,904 3 0,0225747 0,4591785 224,6 57,7 3,893 stabilin 1 CDNA: FLJ21706 fis, clone 0,0131398 0,402701 642,4 165,2 3,889 COL09945 BCL2-like 14 (apoptosis 0,00221 0,2672586 646,8 166,7 3,88 facilitator) endonuclease domain 264 0,0004664 0,1940962 363,1 93,6 3,879 containing 1 homer homolog 2 37 4,67E-05 0,1541482 411,5 106,2 3,875 (Drosophila)

MRNA; cDNA DKFZp434N02 20 (from clone DKFZp434N02 0,0011304 0,2251019 890 231 3,853 20) guanylate cyclase activator 1A 0,0118389 0,3891601 196,9 51,1 3,853 (retina) regulator of G- protein 0,0101599 0,3757604 134,1 34,9 3,842 signaling 20 complement factor H /// complement factor H- 0,0206706 0,4485902 74,8 19,5 3,836 related 1 quinolinate phosphoribosyl transferase (nicotinate- nucleotide pyrophosphory lase (carboxylating) 0,0047126 0,3197234 278,3 73,1 3,807 )

271 0,000108 0,1541482 304,1 80,5 3,778 paraoxonase 2 Ets homologous 0,0068533 0,344282 1004,5 267,5 3,755 factor phospholipid 0,0022486 0,2690201 57,8 15,5 3,729 scramblase 4 0,022179 0,4567432 135,3 36,4 3,717 myosin X 0,0020777 0,2599502 70,2 18,9 3,714 follistatin prostaglandin F2 receptor negative 0,0131804 0,4030416 225,5 60,9 3,703 regulator

UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 12 0,0387338 0,5072367 3319,8 905,4 3,667 (GalNAc-T12) DKFZP564O0 267 0,000264 0,1708912 66,9 18,3 3,656 823 protein

fatty acid binding protein 3, muscle and heart (mammary- derived growth 0,014124 0,4075754 405,7 111,6 3,635 inhibitor) ets homologous 0,0291209 0,4811681 216,4 60 3,607 factor

oligonucleotide /oligosaccharid e-binding fold 0,0018083 0,2490398 4687,2 1302,6 3,598 containing 2A interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation 0,0071785 0,3462686 108,9 30,4 3,582 factor 1, p35) beta-site APP- cleaving 0,04198 0,5123056 255,1 72 3,543 enzyme 1 0,0027505 0,2846759 1926,1 546 3,528 mucolipin 2

stomatin 235 1,75E-05 0,1541482 250,2 71,8 3,485 (EPB72)-like 1

Immunoglobuli 0,0166367 0,425997 499,8 144 3,471 n epsilon chain

A kinase (PRKA) anchor protein (gravin) 228 9,86E-05 0,1541482 34,3 9,9 3,465 12 Transcribed 0,0055367 0,3279506 270,3 79 3,422 locus tweety homolog 2 0,034351 0,4961771 1033,7 304,4 3,396 (Drosophila) phospholipase 0,040654 0,5112983 271,7 80,5 3,375 A2, group V peptidylglycine alpha- amidating monooxygenas 0,0491023 0,5242469 409,9 121,5 3,374 e chromosome 21 open reading frame 135 0,0006555 0,2000194 73,5 21,9 3,356 42 RAS guanyl releasing protein 1 (calcium and DAG- 185 0,0002483 0,1674922 328,7 98,4 3,34 regulated) Full length insert cDNA clone 0,0016114 0,2418041 585,7 175,8 3,332 YB31B05

tumor necrosis factor receptor superfamily, member 11a, 0,0030824 0,2932482 109,3 33 3,312 NFKB activator guanylate cyclase 1, soluble, alpha 0,0076154 0,3505421 131,8 39,8 3,312 3 0,0193729 0,4417307 5384,2 1630,8 3,302 cathepsin C Transcribed 0,0150151 0,4143327 203,9 61,8 3,299 locus lanosterol synthase (2,3- oxidosqualene- lanosterol 0,0013798 0,238971 930,1 282,6 3,291 cyclase) solute carrier family 37 (glycerol-3- phosphate transporter), 183 0,0004615 0,1940962 484 147,2 3,288 member 3 discoidin, CUB and LCCL domain 0,0077193 0,3505421 170,3 52,3 3,256 containing 1 prostaglandin- endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenas 0,0186765 0,4390102 1348,3 414,4 3,254 e) 0,0050558 0,3244435 585,6 180,1 3,252 formin-like 2 StAR-related lipid transfer (START) domain 0,028078 0,4758739 450 138,7 3,244 containing 5 STAM binding 0,03559 0,4984838 207,4 64 3,241 protein-like 1 ankyrin repeat and BTB (POZ) domain 252 0,0006348 0,1980347 704,5 219,1 3,215 containing 2 ADP- ribosylation 0,0154154 0,4170396 200 62,2 3,215 factor-like 5B Wolfram syndrome 1 0,0327223 0,493025 512,1 161 3,181 (wolframin) 0,0272718 0,4727831 404,2 127,9 3,16 stabilin 1 CD36 molecule (thrombospond 0,0366703 0,5014773 189,6 60 3,16 in receptor) CD36 molecule (thrombospond 0,045981 0,5183695 749,7 237,4 3,158 in receptor) HESX 0,0039312 0,3127885 445,1 141,6 3,143 homeobox 1

interleukin 18 0,0095733 0,3688312 626,1 201,1 3,113 binding protein prostaglandin- endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenas 0,0152651 0,415674 1508,4 485,3 3,108 e) CDNA FLJ39159 fis, clone OCBBF200216 92 0,0006197 0,1980347 204 65,7 3,105 1 Fucosyltransfe rase 1 (galactoside 2- alpha-L- fucosyltransfer ase, H blood 203 0,0006193 0,1980347 54,6 17,7 3,085 group) potassium inwardly- rectifying channel, subfamily J, 0,0130928 0,4026559 843,6 275,9 3,058 member 2 Transcribed 155 9,80E-06 0,115911 57,6 18,9 3,048 locus dystrobrevin, 0,0015455 0,2418041 106,2 34,9 3,043 alpha integrin, alpha 0,0081101 0,3561466 65,7 21,6 3,042 9

phosphodieste rase 4B, cAMP- specific (phosphodieste rase E4 dunce homolog, 0,0128242 0,4006379 342,4 113,5 3,017 Drosophila)

coiled-coil- helix-coiled-coil- helix domain 0,0033621 0,3039332 3760,9 1248,3 3,013 containing 7 hydroxysteroid (11-beta) dehydrogenas 7 0,0001375 0,1541482 1561,4 518,4 3,012 e 1 0,0301515 0,4831575 75,9 25,2 3,012 formin-like 2

steroid 5 alpha- 0,0019781 0,2562745 570,1 190 3,001 reductase 3 growth arrest- 0,0032314 0,2999829 146,7 49 2,994 specific 6

Homo sapiens, clone IMAGE:51702 0,0046349 0,3197234 64,2 21,6 2,972 50, mRNA fatty acid binding protein 3, muscle and heart (mammary- derived growth 0,0457338 0,5177385 354,8 119,5 2,969 inhibitor)

Homo sapiens, clone IMAGE:38812 0,0024277 0,2726804 55,8 18,8 2,968 24, mRNA cytochrome P450, family 51, subfamily A, polypeptide 0,0170232 0,427416 506,4 171,8 2,948 1

oligonucleotide /oligosaccharid e-binding fold 0,0163827 0,4235969 363,1 123,2 2,947 containing 2A prostaglandin F2 receptor negative 154 6,26E-05 0,1541482 336,2 114,3 2,941 regulator solute carrier organic anion transporter family, member 0,0097696 0,369912 221,7 75,8 2,925 2B1 hypothetical gene supported by AK127288; 0,0022558 0,2690842 647,2 222,8 2,905 AY343901

thioredoxin domain containing 3 168 0,0002512 0,1674922 66,9 23,1 2,896 (spermatozoa) wingless-type MMTV integration site family, member 0,0086636 0,3602917 1283,3 443,8 2,892 5A galactose mutarotase (aldose 1- 0,0310531 0,4871817 753,8 261,5 2,883 epimerase) 0,0451846 0,516331 1372,1 476,9 2,877 optineurin phosphatidylet hanolamine binding protein 0,0095746 0,3688312 737,5 256,7 2,873 1 solute carrier family 41, 0,0298942 0,4826515 362,9 126,4 2,871 member 2 leucine rich repeat 0,0010878 0,2213833 668,7 233,6 2,863 containing 50 CD226 0,0170662 0,427783 98 34,3 2,857 molecule myosin, light chain 9, 0,0094986 0,3688312 183,7 64,6 2,844 regulatory

phosphodieste rase 4B, cAMP- specific (phosphodieste rase E4 dunce homolog, 0,014821 0,4119489 791,5 278,5 2,842 Drosophila) Transcribed 0,0287767 0,4791082 536,5 188,9 2,84 locus beta-1,3-N- acetylgalactos aminyltransfer ase 1 (globoside 0,0249795 0,4686871 113,6 40,1 2,833 blood group) phosphatidylet hanolamine binding protein 0,0089417 0,3635583 1404,7 500,1 2,809 1 C-type lectin domain family 0,0200389 0,4476045 229,9 82,1 2,8 2, member D Transcribed 0,0188361 0,4401921 52,3 18,7 2,797 locus

histone cluster 0,0152648 0,415674 1272,8 456,6 2,788 1, H2bk aquaporin 3 (Gill blood 0,0131651 0,402799 843,5 305,1 2,765 group)

chromosome 5 open reading 0,0045155 0,3197234 120,8 43,9 2,752 frame 13

steroid 5 alpha- 0,0191512 0,4416246 29,7 10,8 2,75 reductase 3 Galactose mutarotase (aldose 1- 0,0195979 0,4445887 416,7 151,5 2,75 epimerase) Ubiquitin B (UBB) mRNA, 3' UTR and genetic suppressor 0,0203365 0,4485902 96,9 35,3 2,745 element

phosphodieste rase 4B, cAMP- specific (phosphodieste rase E4 dunce homolog, 0,0239484 0,4638862 45,3 16,5 2,745 Drosophila) CNKSR family 0,0015232 0,2418041 65,3 23,9 2,732 member 3

chromosome 1 open reading 0,0138808 0,4056295 82,5 30,2 2,732 frame 115 CDNA FLJ31066 fis, clone HSYRA200115 0,0450482 0,516331 113,6 41,6 2,731 3

transient receptor potential cation channel, subfamily V, 0,0285239 0,4776731 1935,4 708,9 2,73 member 2 quinolinate phosphoribosyl transferase (nicotinate- nucleotide pyrophosphory lase (carboxylating) 138 0,0005374 0,1940962 321,6 118 2,725 ) complement 0,0139391 0,4062323 52,6 19,3 2,725 factor H Transcribed 0,0067711 0,3434229 533 196,7 2,71 locus C-type lectin domain family 0,0143475 0,4083537 52,5 19,4 2,706 2, member D transforming growth factor, 0,004345 0,3197234 1062,3 392,8 2,704 alpha solute carrier organic anion transporter family, member 0,016586 0,4254648 66,9 24,8 2,698 2B1 0,00292 0,2895505 243,2 91,2 2,667 proline rich 6 platelet- derived growth factor receptor- 0,0270734 0,4727831 436,5 164,1 2,66 like fatty acid 0,0069086 0,345588 327,6 123,3 2,657 desaturase 2 Transcribed 0,0016844 0,2418041 235,2 88,7 2,652 locus carbonyl 0,0386085 0,5072367 699 264,9 2,639 reductase 3

cytochrome P450, family 4, subfamily V, 35 0,0001355 0,1541482 60,1 22,9 2,624 polypeptide 2 Fucosyltransfe rase 1 (galactoside 2- alpha-L- fucosyltransfer ase, H blood 0,0170963 0,4279946 102,1 39 2,618 group) presenilin 2 (Alzheimer 0,0012928 0,2351565 277,5 106,2 2,613 disease 4) sphingosine-1- phosphate 66 0,0002334 0,16423 797 306,1 2,604 lyase 1 57 0,0005164 0,1940962 1233,1 474,3 2,6 KIAA0100

basic leucine zipper transcription 0,0045099 0,3197234 762,2 293,6 2,596 factor, ATF-like transmembran 0,0103721 0,3766691 155,9 60,1 2,594 e protein 9 transforming growth factor, beta-induced, 0,032942 0,4934061 1931,9 749,4 2,578 68kDa

dual adaptor of phosphotyrosin e and 3- phosphoinositi 0,0033876 0,3039332 855,9 333,9 2,563 des non imprinted in Prader- Willi/Angelman 16 0,0009784 0,2205294 164,4 64,3 2,557 syndrome 1 protein tyrosine phosphatase, receptor type, 0,0157465 0,419357 82,2 32,2 2,553 M

protein kinase, 95 0,0005037 0,1940962 403,5 158,2 2,551 X-linked

exostoses 0,0378017 0,5070433 269,3 106,2 2,536 (multiple)-like 2 ral guanine nucleotide dissociation 0,0242417 0,4655479 943,1 372,4 2,532 stimulator hypothetical gene supported by AK127288; 0,0442208 0,5146068 191,1 75,6 2,528 AY343901 Family with sequence similarity 26, 29 0,0002339 0,16423 123,8 49,1 2,521 member F gap junction protein, beta 2, 0,0103479 0,3766691 481,7 191,9 2,51 26kDa amidohydrolas e domain 0,0055687 0,3279506 149,3 59,6 2,505 containing 2

Immunoglobuli n epsilon chain /// Epsilon , IgE=membran e-bound IgE, epsilon m/s isoform {alternative splicing} [human, mRNA 0,0031584 0,2977337 222,6 88,9 2,504 Partial, 216 nt] Family with sequence similarity 26, 0,0019935 0,2564579 342,2 137,4 2,491 member F Transcribed locus, moderately similar to NP_689672.2 hypothetical protein LOC146556 [Homo 0,0012247 0,2280729 759,8 305,2 2,49 sapiens] 0,0078737 0,3531539 258,4 103,9 2,487 proline rich 6 CD40 molecule, TNF receptor superfamily 0,0052159 0,3267775 279,8 112,6 2,485 member 5 G protein- coupled 0,0032797 0,3012437 1525,8 616 2,477 receptor 137B chemokine (C- C motif) ligand 0,0364564 0,5004966 2600,6 1051,9 2,472 5 dedicator of 0,0199199 0,4467943 87,3 35,4 2,466 cytokinesis 1 adenylate cyclase 1 0,0210734 0,4498978 40,6 16,5 2,461 (brain) NAD(P)H dehydrogenas 0,0439894 0,5143739 351,7 143,2 2,456 e, quinone 1 lymphotoxin alpha (TNF superfamily, 0,0472991 0,521195 93,6 38,5 2,431 member 1) deafness, autosomal 0,017775 0,4331491 307,2 126,7 2,425 dominant 5 Full length insert cDNA clone 0,0400064 0,5087876 46,3 19,1 2,424 ZD68B12 sarcoglycan, beta (43kDa dystrophin- associated 24 0,0003261 0,1765299 61,3 25,3 2,423 glycoprotein) somatostatin 0,0177214 0,4331491 56,5 23,4 2,415 receptor 2 CDNA clone IMAGE:530215 0,0433573 0,5130671 46,6 19,3 2,415 8

insulin induced 81 0,0009518 0,2205071 2229,4 924,2 2,412 gene 1 four jointed box 1 0,0016172 0,2418041 182,8 75,9 2,408 (Drosophila)

chromosome 5 open reading 46 0,0009092 0,2205071 476,2 198,4 2,4 frame 13 sialophorin (leukosialin, 0,0118735 0,3891988 872,3 363,8 2,398 CD43) wingless-type MMTV integration site family, member 0,018131 0,4355503 297,3 124,3 2,392 5A 0,0037968 0,3114214 61,7 25,9 2,382 phosphatase and actin 0,0041443 0,3163535 77,9 32,7 2,382 regulator 1 hexose-6- phosphate dehydrogenas e (glucose 1- dehydrogenas 0,0014797 0,2418041 935,7 394,3 2,373 e) Transcribed 0,0043039 0,3197234 156,6 66,4 2,358 locus 0,0019094 0,2536814 196,7 83,5 2,356 tuftelin 1 0,0208392 0,448736 58,9 25 2,356 LP2209 RNA binding motif, single stranded interacting 0,0034979 0,3039332 133,5 56,7 2,354 protein 2 unc-51-like kinase 2 (C. 0,0316704 0,4892849 59,8 25,4 2,354 elegans) proprotein convertase subtilisin/kexin 0,0237474 0,4633196 115,5 49,2 2,348 type 5 beta-site APP- cleaving 0,0380734 0,5071739 567,2 241,6 2,348 enzyme 1

A kinase (PRKA) anchor protein 2 /// 0,002467 0,274856 2794,7 1191,6 2,345 PALM2-AKAP2 UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer 0,0048309 0,3211399 492,2 210,1 2,343 ase-like 4 interleukin 21 0,0412048 0,5116636 266,3 113,7 2,342 receptor chromosome 14 open reading frame 0,0142092 0,4080969 81,4 34,8 2,339 65

H2B histone family, member S /// histone 0,0290045 0,4802991 390,6 167 2,339 cluster 1, H2bk B-cell CLL/lymphoma 0,0216065 0,4524803 173,1 74,2 2,333 2 CTTNBP2 N- 0,0019827 0,2562745 130,9 56,2 2,329 terminal like fucosyltransfer ase 1 (galactoside 2- alpha-L- fucosyltransfer ase, H blood 0,0010539 0,2205294 156,7 67,3 2,328 group)

uncoupling protein 2 (mitochondrial, 0,007619 0,3505421 4621,3 1985,5 2,328 proton carrier) zinc finger 0,0405086 0,5106012 174,9 75,3 2,323 protein 618 endonuclease domain 0,0225112 0,4589112 141,6 61 2,321 containing 1

triggering receptor expressed on 0,0486509 0,5232444 4358,1 1880,7 2,317 myeloid cells 2 apolipoprotein 0,028271 0,4764283 1605,3 693,9 2,313 C-I

uncoupling protein 2 (mitochondrial, 0,0118652 0,3891601 1175,6 509,8 2,306 proton carrier) tumor protein p53 inducible 0,0191339 0,4415733 283,5 123 2,305 protein 3 0,0216999 0,4524803 160,4 69,6 2,305 A kinase (PRKA) anchor protein 2 /// 0,0021005 0,2600279 2154,8 937 2,3 PALM2-AKAP2 malic enzyme 3, NADP(+)- dependent, 0,0475502 0,521195 279,5 121,6 2,299 mitochondrial purinergic receptor P2Y, G-protein 0,002895 0,2888396 72 31,4 2,293 coupled, 14

solute carrier family 8 (sodium/calciu m exchanger), 0,0047884 0,3204477 365,5 159,5 2,292 member 1

0,0032271 0,2999829 4210,6 1842,9 2,285 CD81 molecule

solute carrier family 22 (organic cation transporter), 0,0231714 0,4622022 71,4 31,3 2,281 member 16 mannose-6- phosphate 0,0122622 0,3928661 200 88 2,273 protein p76 Ras association (RalGDS/AF-6) domain family 0,025478 0,4702698 2685,7 1181,4 2,273 5 CLR 64 0,0003132 0,1742973 46,3 20,4 2,27 pseudogene lymphocyte antigen 6 complex, locus 0,0027716 0,2846759 831,7 366,8 2,267 E

Full-length cDNA clone CS0DL008YP0 9 of B cells (Ramos cell line) Cot 25- normalized of Homo sapiens 0,0430137 0,5129646 284,5 125,9 2,26 (human) low density lipoprotein receptor- related protein 0,0442211 0,5146068 34,8 15,5 2,245 11 microtubule- associated 0,0395173 0,5080329 489,6 218,5 2,241 protein 1S acyl-CoA synthetase long-chain family member 0,0063479 0,3392683 1535,4 686,5 2,237 3

insulin induced 181 0,0006396 0,1980347 809,8 362,7 2,233 gene 1

calcium/calmo dulin- dependent 0,0111463 0,3854674 300,5 134,6 2,233 protein kinase I

antigen p97 (melanoma associated) identified by monoclonal antibodies 0,0120016 0,3911283 123,6 55,4 2,231 133.2 and 96.5 Transcribed 0,0210581 0,4498978 188,5 84,6 2,228 locus interleukin 18 0,0262212 0,4705663 84,5 38 2,224 receptor 1

steroid-5-alpha- reductase, alpha polypeptide 1 (3-oxo-5 alpha- steroid delta 4- dehydrogenas 0,0014968 0,2418041 130,3 58,8 2,216 e alpha 1)

insulin induced 103 0,0003719 0,1824597 4038,5 1827,6 2,21 gene 1 presenilin 2 (Alzheimer 0,0022241 0,2672586 233 105,5 2,209 disease 4) 266 0,0002688 0,1708912 296,2 134,3 2,206 calsyntenin 1 cytoplasmic polyadenylatio n element binding protein 0,0056025 0,3279506 1355,1 614,7 2,204 2 Ly6/neurotoxin 0,0075138 0,3505421 116,7 53 2,202 1 high mobility group nucleosomal binding domain 217 0,0003026 0,1742973 3778 1719,1 2,198 3 interleukin 21 0,0213352 0,4517641 84,2 38,3 2,198 receptor

Schlafen family 0,0082873 0,3568017 917 417,3 2,197 member 5 pre-B-cell leukemia 0,0092728 0,3687888 188,1 86 2,187 homeobox 4 schlafen family 0,0042819 0,3197234 1142,1 522,5 2,186 member 5 tripartite motif- 0,0216611 0,4524803 93,8 42,9 2,186 containing 31 CD276 0,0091874 0,3683909 2401,9 1101,2 2,181 molecule FYVE, RhoGEF and PH domain 0,0023941 0,2720759 4854,9 2228,4 2,179 containing 2 CTTNBP2 N- 0,0195643 0,4445877 290,1 133,4 2,175 terminal like baculoviral IAP repeat- 0,0275546 0,473162 3652,9 1679,2 2,175 containing 3

histone cluster 0,0249125 0,468375 25,8 11,9 2,168 1, H2bc beta-1,3-N- acetylgalactos aminyltransfer ase 1 (globoside 0,0381735 0,5072367 38,8 17,9 2,168 blood group) DENN/MADD domain 0,002882 0,288618 236,9 109,7 2,16 containing 3 RAB7B, member RAS oncogene 0,0158502 0,4196703 618,2 286,2 2,16 family C-type lectin domain family 0,0039649 0,3133541 41,2 19,1 2,157 2, member D

A kinase (PRKA) anchor protein 2 /// 0,012838 0,4006379 2229,3 1034,2 2,156 PALM2-AKAP2 FYVE, RhoGEF and PH domain 0,0190937 0,4414157 895,7 416 2,153 containing 2 gap junction protein, alpha 142 0,000459 0,1940962 35,1 16,4 2,14 4, 37kDa phospholipase D family, 0,0010439 0,2205294 48 22,5 2,133 member 4 similar to 40S ribosomal 0,030004 0,4827695 682,6 320,3 2,131 protein S16 sushi domain 0,0110184 0,3829822 702,8 329,9 2,13 containing 1 squalene 0,0206603 0,4485902 140,2 65,9 2,127 epoxidase chromosome 14 open reading frame 0,0013072 0,2351565 341,7 160,7 2,126 24 major histocompatibili ty complex, class II, DP 0,0338315 0,4946955 1116,8 525,5 2,125 alpha 1 myo-inositol 1- phosphate 23 0,000356 0,1819093 82 38,6 2,124 synthase A1 proprotein convertase subtilisin/kexin 0,0046222 0,3197234 312,6 147,3 2,122 type 5

PTPRF interacting protein, binding protein 0,0268138 0,4727831 1083,2 510,7 2,121 2 (liprin beta 2) Transcribed 0,0030611 0,2931097 118,3 56 2,112 locus phosphatidylet hanolamine binding protein 0,0271604 0,4727831 1508,3 715,2 2,109 1 cytoplasmic polyadenylatio n element binding protein 0,0168972 0,4266945 449,4 213,2 2,108 2 solute carrier organic anion transporter family, member 0,0137009 0,4046068 123,4 58,8 2,099 2B1 147 0,0003413 0,1794286 252,8 120,7 2,094 glutaminase (clone 1NIB-4) normalized cDNA library 0,0359334 0,4990053 715,3 342,4 2,089 sequence

EF-hand domain family, 102 0,0003771 0,1824597 868,3 416,4 2,085 member D2 SAM and SH3 domain 0,0051367 0,3258567 962,8 462,2 2,083 containing 1 beta-site APP- cleaving 0,0189542 0,4406633 234,3 112,5 2,083 enzyme 1 0,0021295 0,2605196 88,8 42,8 2,075 non imprinted in Prader- Willi/Angelman 0,0064896 0,3398648 27,6 13,3 2,075 syndrome 1 Transcribed 0,0210055 0,4498978 55,5 26,8 2,071 locus membrane- associated ring finger (C3HC4) 0,0335058 0,493712 261,7 126,4 2,07 2

0,0431602 0,5129646 79,2 38,3 2,068 CD22 molecule sphingosine-1- phosphate 0,0055858 0,3279506 55,6 26,9 2,067 lyase 1 anterior pharynx defective 1 homolog B (C. 0,0482918 0,5224951 255,9 124 2,064 elegans) 5 0,0002167 0,1623024 336,5 163,7 2,056 nuclear receptor subfamily 4, group A, 0,0369249 0,5020813 4165,1 2028,4 2,053 member 3 protein phosphatase 1, regulatory (inhibitor) 0,0274779 0,4727831 232,5 113,8 2,043 subunit 14A

chromosome 6 open reading 194 0,0007895 0,2088164 600,8 294,4 2,041 frame 108 0,0171939 0,4290627 62,8 30,8 2,039 myosin X 3-hydroxy-3- methylglutaryl- Coenzyme A synthase 1 143 0,0004574 0,1940962 236,8 116,3 2,036 (soluble) quiescin Q6 sulfhydryl 19 0,0005584 0,1940962 1738,1 855 2,033 oxidase 1 ATPase, class 0,0083801 0,3576553 518 254,8 2,033 V, type 10A SAM and SH3 domain 0,0025172 0,2756013 1153,4 567,7 2,032 containing 1 CD40 molecule, TNF receptor superfamily 0,0039474 0,3127885 2331,7 1150,6 2,027 member 5 hematological and neurological 0,0110977 0,3846606 331,1 163,5 2,025 expressed 1 collagen, type 0,0063628 0,3392834 89,2 44,1 2,023 VI, alpha 2 0,0244803 0,4660137 162,1 80,2 2,021 B-cell linker

MRNA; cDNA DKFZp564C20 3 (from clone DKFZp564C20 0,0326939 0,493025 401,7 198,9 2,02 3) twist homolog 1 (acrocephalosy ndactyly 3; Saethre- Chotzen syndrome) 0,0084145 0,3577471 21,8 10,8 2,019 (Drosophila) BCL2- antagonist/kille 0,0060129 0,3320761 242,2 120 2,018 r 1

golgi autoantigen, golgin 0,0273666 0,4727831 337,9 167,6 2,016 subfamily a, 8A histone cluster 0,0111027 0,3846606 27 13,4 2,015 1, H4h lectin, galactoside- binding, soluble, 1 52 0,0006585 0,2000194 8918,7 4427,9 2,014 (galectin 1) olfactomedin- 0,0076129 0,3505421 43,7 21,7 2,014 like 3

protein phosphatase 2 (formerly 2A), regulatory subunit B'', 0,0424875 0,5127624 353,9 175,7 2,014 alpha endosulfine 0,0069365 0,3458012 198,1 98,4 2,013 alpha 0,0085352 0,3593692 523,9 260,3 2,013 KIAA1128 death- associated protein kinase 0,0115854 0,388941 1748,3 869,1 2,012 1

FK506 binding protein 1B, 0,0317852 0,4894884 362,2 180,4 2,008 12.6 kDa fermitin family homolog 2 0,0049367 0,3216637 33,5 16,7 2,006 (Drosophila) epoxide hydrolase 1, microsomal 0,0486142 0,5230188 570,4 284,4 2,006 (xenobiotic) monocyte to macrophage differentiation- 0,0306263 0,4860078 1618,4 807,8 2,003 associated

serpin peptidase inhibitor, clade B (ovalbumin), 0,0396028 0,5082824 3038,7 1516,8 2,003 member 9 testis-specific 0,0422681 0,5127624 202,3 101,1 2,001 kinase 2 fatty acid 0,0447212 0,5157417 657 328,4 2,001 desaturase 1 fatty acid 0,0028704 0,288618 160,8 80,4 2 synthase histone cluster 0,019236 0,4417307 24,4 12,2 2 1, H4h hypothetical protein 0,0025155 0,2756013 175,1 87,6 1,999 LOC643977 0,0085595 0,3599473 326,8 163,6 1,998 CD80 molecule ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3- 0,0139848 0,4063023 3683,3 1844,1 1,997 like, yeast)

CDC42 effector protein (Rho GTPase 0,0425733 0,5127624 225,9 113,2 1,996 binding) 2

0,0455793 0,5172371 203,3 101,9 1,995 CD22 molecule hexose-6- phosphate dehydrogenas e (glucose 1- dehydrogenas 0,0285812 0,4776731 374,1 187,7 1,993 e) myristoylated alanine-rich protein kinase 0,0160823 0,4211937 505,9 254 1,992 C substrate Clone 23676 mRNA 0,0044352 0,3197234 177,3 89,2 1,988 sequence caspase 7, apoptosis- related cysteine 0,011928 0,3900499 1812,3 912 1,987 peptidase somatostatin 0,0173292 0,4305249 28,4 14,3 1,986 receptor 2 Full-length cDNA clone CS0DF008YJ1 2 of Fetal brain of Homo sapiens (human) /// Acyl-CoA synthetase long-chain family member 0,0366787 0,5014773 491,2 247,6 1,984 3 family with sequence similarity 40, 0,0021144 0,260519 74,7 37,7 1,981 member B

chromosome 6 open reading 0,0034325 0,3039332 448,6 226,4 1,981 frame 108

chromosome 5 open reading 0,0174973 0,4311243 115,2 58,3 1,976 frame 13 0,016123 0,4213791 51,7 26,2 1,973 SID1 transmembran e family, 0,0178413 0,4339293 3616,5 1833,3 1,973 member 2 Transcribed 0,0211935 0,4510528 51,7 26,2 1,973 locus spondin 2, extracellular 0,0169377 0,426752 216,2 109,7 1,971 matrix protein family with sequence similarity 26, 133 0,0009027 0,2205071 2146 1089,4 1,97 member F FYVE, RhoGEF and PH domain 0,0323844 0,4917015 1056,8 536,8 1,969 containing 2

ELOVL family member 7, elongation of long chain fatty 0,0299387 0,4826515 916,8 466,6 1,965 acids (yeast) family with sequence similarity 26, 257 0,0005581 0,1940962 2854 1453,1 1,964 member F chromosome 17 open reading frame 0,0012138 0,2279498 1640,7 835,2 1,964 58 tubulin, alpha 0,0355988 0,4984838 12176,5 6200,6 1,964 1a tetratricopeptid e repeat 0,0126804 0,3986779 93,1 47,5 1,96 domain 9 0,011307 0,3858197 258,6 132,2 1,956 phenazine biosynthesis- like protein domain 0,0066093 0,3412079 43,6 22,3 1,955 containing chromosome 10 open reading frame 0,0497666 0,5252551 1354,8 692,9 1,955 128 0,039248 0,5080329 14,4 7,4 1,946 KIAA1462 C-type lectin domain family 0,0263104 0,4705663 1396,1 717,9 1,945 4, member A integrin, alpha 0,0210581 0,4498978 58,7 30,2 1,944 9

chromosome 6 open reading 0,0393196 0,5080329 1127,6 580,3 1,943 frame 115 dystrobrevin, 0,0187887 0,4401921 94,4 48,7 1,938 alpha

transmembran 0,0184776 0,4377222 38,5 19,9 1,935 e protein 45B COMM domain 0,0019475 0,2561092 1629,5 844,9 1,929 containing 7 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 0,0453593 0,516644 157,4 81,6 1,929 receptor) chromosome 20 open reading frame 0,0217654 0,4524803 515,5 267,4 1,928 108 hypothetical gene supported by AK127288; 0,0086311 0,3602917 32,9 17,1 1,924 AY343901 RAB GTPase activating 0,0360109 0,4990053 884,8 461,5 1,917 protein 1-like G protein- coupled 0,026482 0,4716298 473,6 247,5 1,914 receptor 35 0,0347212 0,4971024 3998,6 2089,6 1,914 cathepsin B KIAA0746 0,0050426 0,3240923 51,7 27,1 1,908 protein methionine sulfoxide 0,0027122 0,2846641 486 255,1 1,905 reductase A Transmembran 0,0056846 0,3299401 145 76,2 1,903 e protein 110 CD40 molecule, TNF receptor superfamily 0,0078227 0,351443 3769 1980,4 1,903 member 5 sulfatase modifying 0,0224681 0,4585455 807,8 425,4 1,899 factor 1 protein kinase 0,0286397 0,4779166 231,9 122,1 1,899 C, alpha RAB31, member RAS oncogene 0,0058725 0,3307111 3464,3 1829 1,894 family calcium/calmo dulin- dependent protein kinase 0,0067451 0,3434229 101,5 53,6 1,894 IG

fibroblast growth factor receptor 1 (fms- related tyrosine kinase 2, Pfeiffer 0,0016522 0,2418041 202,9 107,3 1,891 syndrome) PHD finger 0,0104267 0,3766691 669,9 355 1,887 protein 15 unc-51-like kinase 2 (C. 0,0234264 0,4629012 28,3 15 1,887 elegans)

dual adaptor of phosphotyrosin e and 3- phosphoinositi 0,0216498 0,4524803 590,2 312,9 1,886 des ral guanine nucleotide dissociation 0,0318739 0,4894884 371,7 197,1 1,886 stimulator gap junction protein, alpha 0,0039923 0,3136271 115,8 61,7 1,877 4, 37kDa coiled-coil domain containing 0,0222205 0,4570164 814,1 433,7 1,877 109B Transcribed 0,0208847 0,448736 90,4 48,2 1,876 locus C-type lectin domain family 0,0366003 0,5012039 1152,6 614,5 1,876 4, member A acetyl- Coenzyme A acetyltransfera se 1 (acetoacetyl Coenzyme A 0,0349286 0,4971024 505,5 269,7 1,874 thiolase) adenosine A3 0,0297015 0,4826515 49,8 26,6 1,872 receptor angiotensin I converting enzyme (peptidyl- dipeptidase A) 0,0395968 0,5082824 71,5 38,2 1,872 1 guanylate binding protein 0,0101736 0,3757604 987,6 528,1 1,87 4 phospholipase C, beta 1 (phosphoinositi 0,0451594 0,516331 69,2 37 1,87 de-specific) DKFZP564O0 0,0125405 0,3964301 148,4 79,5 1,867 823 protein UDP-glucose ceramide glucosyltransfe 0,0059319 0,3309455 1450,6 777,8 1,865 rase nudix (nucleoside diphosphate linked moiety X)-type motif 0,0028304 0,286578 108,5 58,2 1,864 14 Mannosidase, alpha, class 0,0201139 0,4476096 2135,1 1145,7 1,864 1A, member 1 serine/threonin 0,0124168 0,3958534 79,9 42,9 1,862 e kinase 4

chromosome 1 open reading 0,0116631 0,3891601 191,2 102,8 1,86 frame 83 growth arrest- 0,0142806 0,4083534 451 242,5 1,86 specific 6 transmembran 0,0182091 0,436017 42,2 22,7 1,859 e protein 44 spermatid perinuclear RNA binding 220 0,0001967 0,1581555 65 35 1,857 protein Transcribed 0,0103808 0,3766691 183,4 98,9 1,854 locus poliovirus receptor- 0,0026181 0,2797591 23,8 12,9 1,845 related 3

FK506 binding protein 9, 63 0,004226 0,3195803 58,3 31,6 1,845 kDa hypothetical protein 0,005888 0,3307111 1167,8 632,8 1,845 BC009467 Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C- X-C motif) 0,0086201 0,3602917 87,8 47,6 1,845 receptor 5) nuclear receptor subfamily 4, group A, 0,0318683 0,4894884 40,2 21,8 1,844 member 3 CLR 0,0214669 0,4522939 393,2 213,3 1,843 pseudogene renin binding 0,0064209 0,3395481 211,8 115 1,842 protein

histone cluster 0,0240743 0,4645353 212,4 115,3 1,842 1, H2bd coiled-coil domain 0,0201557 0,4477043 647,2 352 1,839 containing 50

cytochrome P450, family 4, subfamily V, 0,0081415 0,3562602 88,2 48 1,838 polypeptide 2

acireductone 0,0085112 0,3591295 1039,6 566 1,837 dioxygenase 1 WDFY family 0,0302305 0,4838898 638,3 348,3 1,833 member 4 Chromosome 21 open reading frame 0,0015075 0,2418041 65 35,5 1,831 2 0,0494244 0,5248641 532,6 290,8 1,831 tetraspanin 4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 0,0021521 0,2626475 51,6 28,2 1,83 receptor) Viral DNA polymerase- transactivated 0,0027928 0,2846759 219,2 119,8 1,83 protein 6 fermitin family homolog 2 0,0011993 0,227535 31,9 17,5 1,823 (Drosophila) dimethylarginin e dimethylamino 0,0167125 0,4260897 343,6 188,6 1,822 hydrolase 2

Homo sapiens, clone IMAGE:51767 54 0,0005609 0,1940962 39,5 21,7 1,82 38, mRNA mitogen- activated protein kinase 0,0167971 0,4260897 1093 601,5 1,817 kinase 3 inter-alpha (globulin) inhibitor H4 (plasma Kallikrein- sensitive 0,0467225 0,5203286 168,7 92,9 1,816 glycoprotein) lymphocyte 0,02016 0,4477043 2206,2 1215,6 1,815 antigen 75 calcium/calmo dulin- dependent protein kinase 0,022259 0,4573509 160,8 88,7 1,813 ID sterile alpha motif domain 0,0247453 0,4667247 135,1 74,5 1,813 containing 4A vav 2 guanine nucleotide exchange 0,04834 0,5225078 290,7 160,5 1,811 factor

Rho guanine nucleotide exchange 88 0,0007666 0,2088164 430,2 237,7 1,81 factor (GEF) 11 filamin B, beta (actin binding 0,0018434 0,2504655 461,6 255,3 1,808 protein 278)

interleukin 2 0,0478655 0,5216357 240 132,8 1,807 receptor, alpha zinc finger 0,0086929 0,3602917 83,2 46,1 1,805 protein 789 sterol regulatory element binding transcription 0,0266594 0,472096 202,8 112,5 1,803 factor 1

UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 1 (GalNAc- 0,0139463 0,4062323 478,7 265,6 1,802 T1) B-cell CLL/lymphoma 0,0040091 0,3144871 56,9 31,6 1,801 2 Boc homolog 0,0055773 0,3279506 76,2 42,3 1,801 (mouse) H2A histone family, member 0,0062431 0,3373399 139 77,3 1,798 Y2

stomatin 0,007671 0,3505421 140,6 78,2 1,798 (EPB72)-like 1 spermatid perinuclear RNA binding 0,0101159 0,3751595 66,5 37 1,797 protein rogdi homolog 0,0397187 0,5087876 416,5 231,8 1,797 (Drosophila) emopamil binding protein (sterol 0,0087423 0,3604104 300,5 167,6 1,793 isomerase) similar to 0,0193665 0,4417307 147,4 82,2 1,793 CG32736-PA Rho guanine nucleotide exchange factor (GEF) 0,0186607 0,4388274 241,3 134,7 1,791 10-like

Fc fragment of IgE, low affinity II, receptor for 0,0376508 0,5065348 1686,1 941,3 1,791 (CD23)

Rho guanine nucleotide exchange 0,0160868 0,4211937 201,8 112,8 1,789 factor (GEF) 11 Transcribed 0,0109958 0,3829822 129,6 72,5 1,788 locus Full length insert cDNA clone 0,0015738 0,2418041 153 85,6 1,787 ZD79H10 ADAMTS-like 0,0469907 0,521195 265,8 148,7 1,787 4

0,0035123 0,3039332 9352,6 5236,4 1,786 CD83 molecule tripartite motif- 0,0251322 0,4697677 165,3 92,6 1,785 containing 36

transmembran 0,038818 0,5072367 99 55,5 1,784 e protein 139

NIMA (never in mitosis gene a)- related kinase 0,0035926 0,3049339 88,5 49,7 1,781 3 0,0028012 0,2846759 317,6 178,4 1,78 glutaminase SFT2 domain 0,0043887 0,3197234 802,8 451 1,78 containing 2 protein phosphatase 3 (formerly 2B), catalytic subunit, gamma 0,0138609 0,4053143 340,1 191,1 1,78 isoform

procollagen- lysine 1, 2- oxoglutarate 5- 0,0352745 0,4980167 359,8 202,1 1,78 dioxygenase 1 CD40 molecule, TNF receptor superfamily 0,0083258 0,3573101 3360 1891,8 1,776 member 5 tweety homolog 3 0,0129647 0,401446 710,8 400,2 1,776 (Drosophila) RAB7, member RAS oncogene 0,0094927 0,3688312 1245,3 701,6 1,775 family-like 1

MRNA; cDNA DKFZp762M12 7 (from clone DKFZp762M12 0,0293386 0,4812171 371,5 209,5 1,773 7) insulin-like growth factor 2 0,0082916 0,3568017 803,4 453,9 1,77 receptor PAP associated domain 0,0175702 0,4322644 285,7 161,5 1,769 containing 5

TBC1 domain family, member 8 (with GRAM 0,0432437 0,5130413 987,6 558,3 1,769 domain) alpha-2- 0,0019313 0,2550576 8459,1 4784,4 1,768 macroglobulin 0,0013309 0,2369309 598 338,4 1,767 annexin A11 LysM, putative peptidoglycan- binding, domain 0,0016466 0,2418041 111,6 63,2 1,766 containing 4 ras homolog gene family, member F (in 0,0197263 0,4458817 1394,3 789,4 1,766 filopodia) family with sequence similarity 69, 0,0282256 0,4764283 404,5 229 1,766 member A DIP2 disco- interacting protein 2 homolog C 0,0291411 0,4812171 203,6 115,3 1,766 (Drosophila) ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3- 0,0080185 0,3545654 214,3 121,6 1,762 like, yeast) Transcribed 0,0151188 0,4149701 1134,6 643,9 1,762 locus calcium/calmo dulin- dependent protein kinase 0,039233 0,5080329 437,9 249 1,759 ID vang-like 1 (van gogh, 0,0129132 0,401446 39 22,2 1,757 Drosophila)

protein kinase, X-linked /// protein kinase, 0,0122612 0,3928661 325 185,2 1,755 Y-linked mitogen- activated protein kinase kinase kinase 0,0019534 0,2561092 83,1 47,4 1,753 13 ceroid- lipofuscinosis, neuronal 6, late infantile, 0,0029293 0,2895505 127,6 72,8 1,753 variant 0,0077134 0,3505421 57,5 32,8 1,753 dystonin SMAD family 0,017422 0,4305249 84,8 48,4 1,752 member 1 CDNA FLJ43417 fis, clone OCBBF202602 0,0077553 0,3510054 49,2 28,1 1,751 5 exostoses 0,0494861 0,5248641 216,3 123,5 1,751 (multiple) 2 dimethylarginin e dimethylamino 0,0472074 0,521195 328,7 187,8 1,75 hydrolase 2 patatin-like phospholipase domain 0,009971 0,3728895 1437,2 821,9 1,749 containing 6 somatostatin 0,0064525 0,3395481 35,3 20,2 1,748 receptor 2 Clone 23700 mRNA 0,0135648 0,4041641 34,6 19,8 1,747 sequence

zinc finger and BTB domain 0,0164458 0,4241141 81,4 46,6 1,747 containing 7C ATPase, H+ transporting, lysosomal 9kDa, V0 0,0022977 0,2707473 118,3 67,8 1,745 subunit e1 beta 1,3- galactosyltrans 0,04076 0,5112983 290,9 166,8 1,744 ferase-like caspase 3, apoptosis- related cysteine 0,0017787 0,2490398 582,1 334,1 1,742 peptidase SID1 transmembran e family, 0,0210918 0,4499392 1375,7 790,2 1,741 member 2 pregnancy- 0,009717 0,3696189 88,4 50,8 1,74 zone protein 0,0098336 0,3706297 704,2 404,8 1,74 KIAA0040

transcription factor 7-like 1 (T-cell specific, 0,014763 0,4119489 48,2 27,7 1,74 HMG-box) Boc homolog 0,0331749 0,4936803 151 87 1,736 (mouse) hypothetical protein 0,0413888 0,5116636 135,2 77,9 1,736 LOC643977

0,0018553 0,2504655 171,2 98,7 1,735 arylsulfatase D chromosome 17 open reading frame 0,0092137 0,3687841 312,2 180,2 1,733 63 interleukin 2 receptor, gamma (severe combined immunodeficie 0,0343234 0,4961771 911,9 526,6 1,732 ncy) inducible T-cell co-stimulator 0,0247554 0,4667247 215,9 124,7 1,731 ligand ring finger 0,0465704 0,5200452 129,5 75 1,727 protein 217 Transcribed 0,027139 0,4727831 105,7 61,4 1,721 locus retinitis pigmentosa GTPase regulator interacting 0,003816 0,3114214 63,3 36,8 1,72 protein 1

acireductone 0,0141169 0,4075754 1762,2 1024,5 1,72 dioxygenase 1 ST3 beta- galactoside alpha-2,3- sialyltransferas 0,0311644 0,488111 1319,2 767,5 1,719 e 5 chromosome 14 open reading frame 0,0355802 0,4984838 509,3 296,2 1,719 139 UDP-glucose ceramide glucosyltransfe 0,0111669 0,3856919 119,2 69,4 1,718 rase potassium channel tetramerisation domain 0,0033197 0,3030127 32,1 18,7 1,717 containing 14 CDNA FLJ30652 fis, clone DFNES200001 163 0,0005956 0,1949966 479,7 279,5 1,716 1 solute carrier family 26, 0,0304446 0,48494 63,5 37 1,716 member 9

PWWP domain 0,0063899 0,3394787 133,8 78 1,715 containing 2A 59 0,0004929 0,1940962 613,7 358,3 1,713 myosin IE /// similar to CDK105 0,0058998 0,3307111 276,6 161,5 1,713 protein

vascular endothelial 0,0428267 0,5127624 123,2 71,9 1,713 growth factor B

signal transducer and activator of transcription 0,0343762 0,4961771 1213,5 709 1,712 5A chromosome 20 open reading frame 0,0371026 0,5031712 202,3 118,2 1,712 108 5'- nucleotidase, 0,0481248 0,5224951 3761 2197,4 1,712 cytosolic III

trafficking protein particle 0,0217311 0,4524803 960,1 561 1,711 complex 2-like phosphoinositi de-3-kinase, regulatory subunit 3 (p55, 0,0166581 0,425997 63,7 37,3 1,708 gamma) Transcribed 0,008623 0,3602917 143,2 83,9 1,707 locus

reticulocalbin 2, EF-hand calcium 0,0137469 0,4049632 191 111,9 1,707 binding domain RAB GTPase activating 0,0313351 0,4885021 166,8 97,7 1,707 protein 1-like 0,0313349 0,4885021 36 21,1 1,706 KIAA0802 MRNA; cDNA DKFZp686A11 113 (from clone DKFZp686A11 0,0044328 0,3197234 47,4 27,8 1,705 113) transmembran 0,0051399 0,3258567 16,2 9,5 1,705 e protein 47 protein phosphatase 3 (formerly 2B), catalytic subunit, gamma 0,0192036 0,4417307 270,8 158,8 1,705 isoform 158 0,0008448 0,2147006 161,2 94,6 1,704

UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 1 (GalNAc- 0,0055193 0,3279506 760 446,1 1,704 T1)

chromosome 9 open reading 0,0478064 0,5214073 156,4 91,8 1,704 frame 103 ATP synthase mitochondrial F1 complex assembly 0,0413297 0,5116636 126,2 74,1 1,703 factor 1 CD74 molecule, major histocompatibil ity complex, class II 0,0478468 0,5215936 13737,1 8067,3 1,703 invariant chain

tight junction protein 1 (zona 0,0128971 0,401446 30,3 17,8 1,702 occludens 1)

0,0046765 0,3197234 419,2 246,5 1,701 sorting nexin 8

guanine nucleotide binding protein (G protein), alpha 11 (Gq 0,0413403 0,5116636 77,9 45,8 1,701 class) adenylate cyclase 1 0,0172587 0,4296992 38,6 22,7 1,7 (brain) 0,0450694 0,516331 3243 1907,4 1,7 syndecan 4 CASP8 and FADD-like apoptosis 0,013817 0,4051745 33,3 19,6 1,699 regulator 17 0,0007298 0,2087617 211,9 124,9 1,697 stratifin transmembran 0,0054285 0,3274124 35,3 20,8 1,697 e protein 44 DnaJ (Hsp40) homolog, subfamily B, 0,0404649 0,5104796 658,6 388,3 1,696 member 6

glucosidase, alpha; acid (Pompe disease, glycogen storage 0,0314053 0,4885021 639,1 377,1 1,695 disease type II) Rho-related BTB domain 0,041295 0,5116636 138,5 81,7 1,695 containing 3 zinc finger 0,0179433 0,4352115 36,6 21,6 1,694 protein 789 cyclin- dependent 0,0180654 0,4355503 264,9 156,4 1,694 kinase 6

interleukin 18 0,025303 0,4702698 120,3 71 1,694 binding protein

platelet- derived growth factor alpha 0,0191732 0,4417307 135,8 80,3 1,691 polypeptide

interleukin 15 0,0371356 0,5031712 1838,9 1087,7 1,691 receptor, alpha chromosome 9 open reading 0,0044533 0,3197234 682,2 404 1,689 frame 52

adaptor-related protein complex 1, 0,0017465 0,2455456 504 298,6 1,688 beta 1 subunit emopamil binding protein (sterol 0,0243761 0,4660137 347,3 205,9 1,687 isomerase) CLR 0,0475096 0,521195 54,8 32,5 1,686 pseudogene RNA binding motif, single stranded interacting 0,0018153 0,2493757 146,3 86,8 1,685 protein 2 wingless-type MMTV integration site family, member 0,0336949 0,4945732 38,9 23,1 1,684 5B torsin family 3, 0,0443409 0,5146943 234,8 139,4 1,684 member A

phosphatidylin ositol 4-kinase 0,0232348 0,4625449 1043,8 620,1 1,683 type 2 alpha

5'-nucleotidase domain 0,0495833 0,524953 65,8 39,1 1,683 containing 2 selenocysteine 0,0388665 0,5075295 126,3 75,2 1,68 lyase transmembran 0,0432354 0,5130413 170,5 101,6 1,678 e protein 9 0,0336896 0,4945732 82 48,9 1,677 ribokinase spermatid perinuclear RNA binding 0,0074252 0,3504479 60 35,8 1,676 protein

guanylate cyclase 1, 0,0010608 0,2205294 33 19,7 1,675 soluble, beta 3

0,0029137 0,2895505 54,1 32,3 1,675 dual oxidase 1 Transcribed 0,0243799 0,4660137 151,7 90,6 1,674 locus aldehyde dehydrogenas e 4 family, 0,0257745 0,4702698 92,4 55,2 1,674 member A1 Transcribed 0,0046425 0,3197234 18,4 11 1,673 locus vang-like 1 (van gogh, 0,0037721 0,3114214 22,9 13,7 1,672 Drosophila) UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 1 (GalNAc- 0,0200013 0,4476045 650,1 388,8 1,672 T1) MRNA; cDNA DKFZp667I047 (from clone DKFZp667I047 0,0431669 0,5129646 60,8 36,4 1,67 ) mitogen- activated protein kinase 0,0229523 0,461565 952,7 570,7 1,669 kinase 3 FYVE, RhoGEF and PH domain 0,0127703 0,4003342 499 299,2 1,668 containing 2 unc-51-like kinase 2 (C. 0,0200281 0,4476045 63,9 38,3 1,668 elegans)

diazepam binding inhibitor (GABA receptor modulator, acyl- Coenzyme A binding 0,0273726 0,4727831 5116,8 3067,4 1,668 protein)

solute carrier family 8 (sodium/calciu m exchanger), 0,0491736 0,524496 97,7 58,6 1,667 member 1

MRNA; cDNA DKFZp586E15 1 (from clone DKFZp586E15 0,0223802 0,4581196 99,8 59,9 1,666 1)

MRNA; cDNA DKFZp762M12 7 (from clone DKFZp762M12 0,042754 0,5127624 448,3 269,2 1,665 7) Hypothetical gene supported by BC034933; 0,04492 0,516331 544,3 327 1,665 BC068085 chromosome 17 open reading frame 0,001958 0,2561092 311,8 187,4 1,664 63 Homo sapiens, clone IMAGE:29607 0,0083818 0,3576553 50 30,1 1,661 04, mRNA PAP associated domain 0,0179776 0,4353079 362,5 218,3 1,661 containing 5 LIM homeobox 0,0293199 0,4812171 18,6 11,2 1,661 2 cerebellin 3 0,0398479 0,5087876 60,6 36,5 1,66 precursor chromosome 22 open reading frame 0,0457922 0,5177385 3320,3 2000,3 1,66 9 0,0011538 0,2260869 739,3 445,5 1,659 glutaminase myristoylated alanine-rich protein kinase 0,0475096 0,521195 1738,9 1048,3 1,659 C substrate CDNA clone IMAGE:384006 0,0333755 0,493712 73,3 44,2 1,658 2 RAB31, member RAS oncogene 0,0391962 0,5080329 3802,5 2293,8 1,658 family TBC1 domain family, member 0,0427072 0,5127624 341 206,2 1,654 2B sidekick homolog 1, cell adhesion molecule 0,0038561 0,3114214 19 11,5 1,652 (chicken)

NIMA (never in mitosis gene a)- related kinase 0,0054549 0,3277436 28,4 17,2 1,651 3

PTPRF interacting protein, binding protein 0,0070095 0,3458012 24,1 14,6 1,651 1 (liprin beta 1) ATPase, H+ transporting, lysosomal 9kDa, V0 0,0127889 0,4003342 244,3 148,1 1,65 subunit e1 phosphate cytidylyltransfe rase 1, choline, 0,0160241 0,4211937 169 102,4 1,65 alpha ubiquitin- conjugating enzyme E2F 0,0207719 0,448736 1520,3 922 1,649 (putative) ras homolog gene family, member F (in 0,0403693 0,5100974 472 286,3 1,649 filopodia)

neurogranin (protein kinase C substrate, 0,0128063 0,4003342 200,4 121,6 1,648 RC3) RAB31, member RAS oncogene 0,0148721 0,4124913 2828,4 1716,4 1,648 family ORAI calcium release- activated calcium 0,0473626 0,521195 273,7 166,1 1,648 modulator 1 Transcribed 0,001353 0,238971 215,7 131 1,647 locus

chromosome 9 open reading 0,015505 0,4178097 303,8 184,5 1,647 frame 98

Chromosome 6 open reading 0,0496658 0,5250037 83,5 50,7 1,647 frame 166 absent in 0,0189651 0,4406633 1383,6 841,2 1,645 melanoma 1

UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 1 (GalNAc- 0,0488723 0,5236318 884,3 537,6 1,645 T1) cadherin, EGF LAG seven- pass G-type receptor 2 (flamingo homolog, 0,0038213 0,3114214 37,3 22,7 1,643 Drosophila)

adaptor-related protein complex 1, sigma 3 0,024121 0,4645353 34 20,7 1,643 subunit hypothetical protein 0,0049713 0,3216637 32 19,5 1,641 BC004360 serine/threonin 0,0351453 0,4974109 758 461,8 1,641 e kinase 40 RUN and FYVE domain 0,0448103 0,516331 1742,2 1061,6 1,641 containing 3 putative homeodomain transcription 0,0100501 0,3745666 637,8 389 1,64 factor 2

chromosome 1 open reading 0,034118 0,4953413 89,2 54,4 1,64 frame 97 lysosomal- associated membrane 0,0358413 0,498925 255,2 155,6 1,64 protein 1

cation channel, sperm- associated, 0,0108902 0,3819324 17,7 10,8 1,639 beta

matrix metallopeptida se 19 /// similar to Matrix metalloprotein ase-19 precursor (MMP-19) (Matrix metalloprotein ase RASI) 0,0097359 0,3696189 676,4 413 1,638 (MMP-18) N-terminal asparagine 0,0345576 0,4967405 799,6 488,9 1,636 amidase forkhead box 0,0143442 0,4083537 20,1 12,3 1,634 C1

0,0057943 0,3304939 2112 1293,3 1,633 synaptogyrin 2 ornithine decarboxylase 0,0068051 0,3438517 89 54,5 1,633 antizyme 3 Full length insert cDNA clone 0,0052955 0,3267775 21,7 13,3 1,632 YX25D06 hematological and neurological 0,0102313 0,3757604 750,3 459,8 1,632 expressed 1 ATPase, H+ transporting, lysosomal V0 0,002373 0,2714688 299,2 183,4 1,631 subunit a2 Chromosome 20 open reading frame 0,0187072 0,4392874 158,7 97,3 1,631 111

cytochrome b5 0,00151 0,2418041 3300,8 2028,2 1,627 reductase 3 cyclin- dependent 0,0403624 0,5100974 235,2 144,6 1,627 kinase 6 peroxisome proliferator- activated 0,0303867 0,4845123 83,1 51,1 1,626 receptor delta protein kinase, cAMP- dependent, regulatory, 0,0116252 0,3891601 82,2 50,6 1,625 type I, beta

uroporphyrinog en III synthase (congenital erythropoietic 0,0388286 0,5072367 270,7 166,6 1,625 porphyria) chromosome 11 open reading frame 0,0156865 0,4191438 124,7 76,8 1,624 67 cysteine-rich secretory protein LCCL domain 0,0245347 0,4660137 17,7 10,9 1,624 containing 1

guanine nucleotide binding protein (G protein), gamma transducing activity 0,0127619 0,4003195 117 72,1 1,623 polypeptide 2 cadherin-like 0,035733 0,4986659 99,5 61,3 1,623 23 family with sequence similarity 129, 0,0460655 0,5186638 2364,8 1457 1,623 member A calcium/calmo dulin- dependent protein kinase (CaM kinase) II 0,0466501 0,5201049 180 110,9 1,623 delta hypothetical 0,0035019 0,3039332 146,5 90,3 1,622 LOC643988 HERPUD family member 0,0049517 0,3216637 949,3 585,1 1,622 2 RAB GTPase activating 0,0167803 0,4260897 411,4 253,6 1,622 protein 1-like

histone cluster 0,0490653 0,5242466 96,7 59,6 1,622 1, H2bf transcription 0,0144295 0,4089854 280,8 173,2 1,621 factor Dp-1 Transcribed 0,0164724 0,4242244 130,3 80,4 1,621 locus Niemann-Pick disease, type 0,0269676 0,4727831 8714,8 5377,2 1,621 C2 isopentenyl- diphosphate delta 0,0433632 0,5130671 800 493,7 1,62 isomerase 1 0,049173 0,524496 102,2 63,1 1,62 ribokinase mitogen- activated protein kinase 0,0074245 0,3504479 2185,8 1350 1,619 kinase 3 zinc finger, DHHC-type 0,015196 0,4155792 23,8 14,7 1,619 containing 19

actin related protein 2/3 complex, subunit 1B, 41kDa /// similar to Actin- related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) 0,0043586 0,3197234 4962,8 3068 1,618 (p41-ARC) ubiquitin specific 0,0386876 0,5072367 39,3 24,3 1,617 peptidase 46

Uncharacterize d gastric 0,0429676 0,5129646 119,5 73,9 1,617 protein ZA32P family with sequence similarity 69, 0,0296198 0,4819829 395,7 244,9 1,616 member A secreted and transmembran 0,0203588 0,4485902 544,5 337,2 1,615 e 1

dual adaptor of phosphotyrosin e and 3- phosphoinositi 0,0233478 0,4626793 91,4 56,6 1,615 des CDNA FLJ14635 fis, clone NT2RP200119 0,0422446 0,5127624 30,2 18,7 1,615 6

MRNA; cDNA DKFZp313M04 17 (from clone DKFZp313M04 0,0443691 0,5146943 83 51,4 1,615 17) zinc finger 0,0135901 0,4041641 104,1 64,5 1,614 protein 618 family with sequence similarity 119, 0,0484807 0,5225078 169,1 104,8 1,614 member B RAP2C, member of RAS oncogene 0,003575 0,3039862 155,9 96,7 1,612 family

diazepam binding inhibitor (GABA receptor modulator, acyl- Coenzyme A binding 0,0278542 0,4745266 5059,1 3141,1 1,611 protein) CDNA FLJ32568 fis, clone SPLEN200009 0,0015895 0,2418041 473,2 293,9 1,61 8 scavenger receptor class 0,0143624 0,4083537 24,3 15,1 1,609 B, member 1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, 0,0053196 0,3267775 29,9 18,6 1,608 member 1 chromosome 17 open reading frame 0,0313503 0,4885021 225,3 140,1 1,608 60 ATPase, H+ transporting, lysosomal 9kDa, V0 0,0341371 0,4953413 211,6 131,6 1,608 subunit e1 CDNA clone IMAGE:451345 0,0349643 0,4971024 312,2 194,2 1,608 3 0,0124847 0,3964301 67,3 41,9 1,606 dystonin Transcribed 0,0176804 0,4331491 40 24,9 1,606 locus Retinitis pigmentosa 9 (autosomal 0,0034527 0,3039332 37,4 23,3 1,605 dominant) collagen, type 0,0035472 0,3039332 74,2 46,3 1,603 VI, alpha 1 Transcribed 0,0366312 0,5012039 412,7 257,4 1,603 locus RNA binding motif, single stranded interacting 0,0223473 0,4580941 3198,3 1997,3 1,601 protein 1 pyridoxal (pyridoxine, vitamin B6) 0,0247229 0,4667247 2001,3 1250,3 1,601 kinase family with sequence similarity 80, 0,0429793 0,5129646 38,9 24,3 1,601 member B filamin B, beta (actin binding 0,0019895 0,2564579 423 264,4 1,6 protein 278)

MRNA; cDNA DKFZp686I181 16 (from clone DKFZp686I181 0,0020344 0,2580609 19,2 12 1,6 16)

18S ribosomal 0,0393715 0,5080329 855,9 534,8 1,6 RNA 0,0252111 0,4702698 1247 779,9 1,599 NAD kinase caspase 10, apoptosis- related cysteine 0,0449997 0,516331 288,3 180,3 1,599 peptidase Fucosyltransfe rase 1 (galactoside 2- alpha-L- fucosyltransfer ase, H blood 0,0141202 0,4075754 61 38,2 1,597 group) 0,033482 0,493712 296,9 185,9 1,597 KIAA1618 pleiomorphic adenoma gene- 0,0342927 0,4961507 410,6 257,1 1,597 like 1 SH3-domain binding protein 0,0096589 0,3696189 356,1 223,2 1,595 2 EH-domain 0,0475123 0,521195 541,5 339,4 1,595 containing 1 purinergic receptor P2X, ligand-gated 0,0155972 0,4179451 1157,4 725,9 1,594 ion channel, 7 sprouty- related, EVH1 domain 0,0352446 0,4980167 575,9 361,6 1,593 containing 2 hypothetical protein 0,004543 0,3197234 181,2 113,8 1,592 LOC729013 Transcribed 0,0200891 0,4476045 39 24,5 1,592 locus secretory carrier membrane 0,0152643 0,415674 89,4 56,2 1,591 protein 4 TNFAIP3 interacting 0,043999 0,5143739 903,9 568 1,591 protein 2 Eukaryotic translation initiation factor 0,009543 0,3688312 129,3 81,3 1,59 2C, 2

adaptor-related protein complex 1, sigma 3 0,0011784 0,2275173 20,8 13,1 1,588 subunit 0,0034626 0,3039332 3288,7 2074,6 1,585 cathepsin H UDP- Gal:betaGlcNA c beta 1,4- galactosyltrans ferase, 0,020874 0,448736 36,3 22,9 1,585 polypeptide 6 thioredoxin-like 0,0349325 0,4971024 391,3 246,9 1,585 4B CASP8 and FADD-like apoptosis 0,0423091 0,5127624 3283,6 2077,4 1,581 regulator ER lipid raft 0,0131225 0,4026559 52,9 33,5 1,579 associated 2

chromosome 9 open reading 0,0144768 0,4092653 40,9 25,9 1,579 frame 9 TCF3 (E2A) fusion partner (in childhood 0,0340586 0,4951364 284,4 180,1 1,579 Leukemia) WD repeat 0,0051802 0,3263638 16,1 10,2 1,578 domain 66 Transcribed 0,0397591 0,5087876 171,6 108,8 1,577 locus abhydrolase domain 0,0099435 0,3723817 811,8 515,5 1,575 containing 12

RAP2B, member of RAS oncogene 0,0158496 0,4196703 57,5 36,5 1,575 family phosphate cytidylyltransfe rase 2, 0,0247203 0,4667247 98,1 62,3 1,575 ethanolamine

leucine-rich repeats and guanylate kinase domain 0,0093975 0,3688312 36,2 23 1,574 containing hypothetical locus 0,0331053 0,4934061 22,8 14,5 1,572 MGC21881 CASP8 and FADD-like apoptosis 0,0392911 0,5080329 3398,3 2164,4 1,57 regulator ubiquitin- conjugating enzyme E2F 0,0190371 0,4414137 245,9 156,7 1,569 (putative) stromal 0,0477147 0,521195 165,1 105,2 1,569 antigen 3 centaurin, 0,0484008 0,5225078 581,5 370,7 1,569 alpha 2 interleukin-1 receptor- associated 0,0395043 0,5080329 760 484,6 1,568 kinase 2 nucleoporin 0,0476153 0,521195 151,2 96,4 1,568 210kDa chromosome 17 open reading frame 0,0226537 0,4599298 120,7 77,1 1,565 67 carbohydrate (N- acetylglucosa mine 6-O) sulfotransferas 0,0244699 0,4660137 478,3 305,6 1,565 e 7 cadherin 18, 0,0075039 0,3505421 39,1 25 1,564 type 2 0,0104778 0,3766691 345,9 221,2 1,564 plexin A1 protein tyrosine phosphatase, receptor type, 0,0395929 0,5082824 61,3 39,2 1,564 F chloride intracellular 0,0174336 0,4305249 757,8 484,7 1,563 channel 2

Notch homolog 1, translocation- associated 0,0207393 0,4485902 234,7 150,2 1,563 (Drosophila)

basic leucine zipper and W2 0,0046482 0,3197234 1011,3 647,4 1,562 domains 2

calmodulin 2 (phosphorylas 0,0047745 0,3199091 11385,1 7290,5 1,562 e kinase, delta) RAB7, member RAS oncogene 0,0038355 0,3114214 1468,4 940,8 1,561 family-like 1 olfactomedin- 0,0129943 0,401446 24,2 15,5 1,561 like 2B 0,019586 0,4445887 2614 1675,5 1,56 melanoregulin

0,035365 0,4983242 82,3 52,8 1,559 arylsulfatase D

platelet- derived growth factor receptor, alpha 0,0027972 0,2846759 45 28,9 1,557 polypeptide promyelocytic 0,0080205 0,3545654 84,1 54 1,557 leukemia phosphoprotei n enriched in 0,0185274 0,4377639 2888,5 1856 1,556 astrocytes 15 transmembran e and coiled- coil domain 0,0397951 0,5087876 88,2 56,7 1,556 family 2 HCV F- transactivated 0,0208962 0,448736 929,6 597,8 1,555 protein 1

coiled-coil domain 0,0217975 0,4527019 793,1 509,9 1,555 containing 90A FYVE, RhoGEF and PH domain 0,0222537 0,4573509 151,3 97,3 1,555 containing 2 ceroid- lipofuscinosis, neuronal 6, late infantile, 0,0401742 0,5095162 242,6 156 1,555 variant 0,0439386 0,5143739 4333,3 2787 1,555 tubulin, beta 6 interleukin 13 receptor, alpha 0,0012551 0,2302772 160,5 103,3 1,554 1

0,018392 0,4370198 190,7 122,7 1,554 CD22 molecule sterile alpha motif domain 0,0079871 0,3545654 24,5 15,8 1,551 containing 4A ATP-binding cassette, sub- family C (CFTR/MRP), 0,0114322 0,3867918 58,1 37,5 1,549 member 11 tudor and KH domain 0,0199014 0,4467943 22,3 14,4 1,549 containing CDNA FLJ11117 fis, clone PLACE100599 0,0332291 0,493712 42,1 27,2 1,548 0 ubiquitin- conjugating enzyme E2F 0,0246406 0,4667247 786 508,2 1,547 (putative) pleiomorphic adenoma gene- 0,0282588 0,4764283 852,9 551,3 1,547 like 1

Transmembran 0,0065497 0,3412079 56,5 36,6 1,544 e protein 177 WAS/WASL interacting protein family, 0,0493881 0,5248641 183,9 119,1 1,544 member 1 pyridoxal (pyridoxine, vitamin B6) 0,0293371 0,4812171 1419,6 920 1,543 kinase lysine-rich 0,0068636 0,344282 127,1 82,4 1,542 coiled-coil 1 UDP- Gal:betaGlcNA c beta 1,4- galactosyltrans ferase, 0,0047712 0,3199091 262 170 1,541 polypeptide 4 tribbles homolog 2 0,0061637 0,3366636 87,7 56,9 1,541 (Drosophila) aldehyde dehydrogenas e 1 family, 0,020321 0,4485902 35,9 23,3 1,541 member L2

complement component 4A (Rodgers blood group) /// complement component 4B (Childo blood 0,0333812 0,493712 162,7 105,6 1,541 group) homeodomain interacting protein kinase 0,0404408 0,5103513 528,3 343,3 1,539 2 family with sequence similarity 40, 0,0066147 0,3412079 34,6 22,5 1,538 member B ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3- 0,0120925 0,3916465 116,6 75,8 1,538 like, yeast) hypothetical protein 0,0213867 0,451823 48,9 31,8 1,538 LOC619208 0,0067603 0,3434229 54,7 35,6 1,537 Mucolipin 3

integrin, alpha X (complement component 3 receptor 4 0,0135698 0,4041641 1902,1 1238,4 1,536 subunit) RUN and FYVE domain 0,007973 0,3545654 156 101,7 1,534 containing 3 toll-like 0,0337398 0,4946955 64,6 42,1 1,534 receptor 7

transmembran 0,005815 0,3304939 165,7 108,1 1,533 e protein 45B guanine nucleotide binding protein (G protein), alpha 11 (Gq 0,0236572 0,4633196 97,2 63,4 1,533 class)

0,0113818 0,3858197 89,8 58,6 1,532 arylsulfatase D chemokine (C- X-C motif) 0,0280959 0,4758739 5249,7 3427,3 1,532 ligand 11

ribosomal protein S6 kinase, 90kDa, 0,0393359 0,5080329 342,4 223,8 1,53 polypeptide 2 0,0413954 0,5116636 91,3 59,7 1,529 KIAA0100 retinoid X 0,0071132 0,3458012 51,2 33,5 1,528 receptor, beta phosphofructo 0,0330453 0,4934061 440 287,9 1,528 kinase, liver CDNA FLJ14200 fis, clone NT2RP300279 0,0180727 0,4355503 56,5 37 1,527 9 chromosome 16 open reading frame 0,0182516 0,436017 471,5 308,7 1,527 33

chromosome 6 open reading 0,0323815 0,4917015 749,9 491,2 1,527 frame 166

complement component 4A (Rodgers blood group) /// complement component 4B (Childo blood 0,0384666 0,5072367 125,1 81,9 1,527 group) Transcribed 0,0070314 0,3458012 35,2 23,1 1,524 locus pyridoxal (pyridoxine, vitamin B6) 0,0450781 0,516331 200,6 131,6 1,524 kinase family with sequence similarity 38, 0,0064506 0,3395481 685,8 450,2 1,523 member A 0,0030406 0,2916576 41,7 27,4 1,522 syndecan 3 arginase, type 0,0080204 0,3545654 136,2 89,5 1,522 II cadherin, EGF LAG seven- pass G-type receptor 2 (flamingo homolog, 0,0038539 0,3114214 47,9 31,5 1,521 Drosophila) TBC1 domain family, member 0,0044633 0,3197234 54,3 35,7 1,521 16

ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein 0,0129636 0,401446 25,4 16,7 1,521 Rac3)

protein tyrosine phosphatase, 0,0145023 0,4095626 82,7 54,4 1,52 mitochondrial 1 HIG1 domain family, member 0,0417888 0,5123056 120,4 79,2 1,52 1A

PTPRF interacting protein, binding protein 0,0480155 0,5221484 115,5 76 1,52 1 (liprin beta 1) Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C- X-C motif) 0,0066177 0,3412079 90,4 59,5 1,519 receptor 5) Full length insert cDNA clone 0,006811 0,3438517 58,6 38,6 1,518 YZ60H05

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 0,0322392 0,4912811 48,7 32,1 1,517 1), member 2 3- hydroxyanthra nilate 3,4- 0,0131082 0,4026559 189 124,7 1,516 dioxygenase chloride intracellular 0,0383695 0,5072367 33,8 22,3 1,516 channel 6

GRAM domain 0,0465094 0,5200452 794,7 524,2 1,516 containing 1A general transcription factor IIH, polypeptide 1, 0,0065569 0,3412079 355,9 234,9 1,515 62kDa acetyl- Coenzyme A carboxylase 0,028194 0,4763619 143,8 94,9 1,515 alpha

Transcribed locus, strongly similar to XP_507970.1 PREDICTED: similar to Hermansky- Pudlak syndrome 1 protein isoform a; Hermansky- Pudlak syndrome gene; Hermansky- Pudlak syndrome type 1 [Pan 0,0415812 0,511693 78,3 51,7 1,515 troglodytes] low density lipoprotein receptor- related protein 0,0046166 0,3197234 16,8 11,1 1,514 6 leucine-rich repeats and transmembran 0,0265698 0,472096 41,6 27,5 1,513 e domains 1 ring finger 0,0039734 0,3134858 2800 1852 1,512 144B

DEAD (Asp- Glu-Ala-Asp) box 0,0089865 0,3639938 1401,7 927 1,512 polypeptide 58

SP100 nuclear 0,0273471 0,4727831 31,9 21,1 1,512 antigen chromatin modifying 0,0232574 0,4625449 749,7 496,3 1,511 protein 4A adenosylmethi onine decarboxylase 0,0360133 0,4990053 1222,7 809,4 1,511 1 PHD finger 0,0034022 0,3039332 108,4 71,8 1,51 protein 15 viral DNA polymerase- transactivated 0,0132435 0,4032981 241,8 160,1 1,51 protein 6 family with sequence similarity 132, 0,0162468 0,4234003 45 29,8 1,51 member B Full-length cDNA clone CS0DF032YA1 1 of Fetal brain of Homo sapiens 0,0280937 0,4758739 38,8 25,7 1,51 (human) 0,0024085 0,2720759 1941,6 1286,8 1,509 stannin 0,0113166 0,3858197 429,9 284,9 1,509 KIAA1128 ELAV (embryonic lethal, abnormal vision, Drosophila)- like 4 (Hu 0,0278627 0,4745266 25,2 16,7 1,509 antigen D) aldolase B, fructose- 0,005343 0,3267775 45,1 29,9 1,508 bisphosphate solute carrier family 25 (mitochondrial carrier; citrate transporter), 0,03804 0,5071739 180,3 119,6 1,508 member 1

fibronectin type III domain 0,038588 0,5072367 43,4 28,8 1,507 containing 5

fibroblast growth factor receptor 1 (fms- related tyrosine kinase 2, Pfeiffer 0,0439239 0,5143739 93,7 62,2 1,506 syndrome) 0,0441355 0,5145349 1472,4 978 1,506 MICAL-like 1

dual specificity phosphatase 0,0033381 0,3038329 214,5 142,5 1,505 16

chromosome 1 open reading 0,0069399 0,3458012 101,6 67,5 1,505 frame 78 Discs, large (Drosophila) homolog- associated 0,0224117 0,4581601 18,8 12,5 1,504 protein 3 G protein- coupled 0,0328991 0,4930759 68,9 45,8 1,504 receptor 180 aldehyde dehydrogenas e 4 family, 0,0053663 0,3267775 89 59,2 1,503 member A1 phospholipase 0,0055922 0,3279506 56,8 37,8 1,503 C-like 1 dihydropyrimidi 0,0069652 0,3458012 3034,8 2018,7 1,503 nase-like 2 ELKS/RAB6- interacting/CA ST family 0,0257952 0,4702698 21,5 14,3 1,503 member 2 kalirin, RhoGEF 0,0076696 0,3505421 41,9 27,9 1,502 kinase phosphofructo 0,016913 0,4266945 424,3 282,5 1,502 kinase, liver HLA-B associated 0,0165138 0,4244908 434,4 289,4 1,501 transcript 5 CDNA FLJ42519 fis, clone BRACE300078 0,0396361 0,5083518 88,1 58,7 1,501 7 0,0070158 0,3458012 36,9 24,6 1,5 Hr44 antigen integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 0,0074592 0,3505421 43,5 29 1,5 receptor) protein phosphatase 1, regulatory (inhibitor) 0,0115328 0,3885321 41,1 27,4 1,5 subunit 14C ribosomal protein S5 /// similar to ribosomal 0,0030078 0,2910986 5782,1 8682 0,666 protein S5 ribosomal 0,0041623 0,3165143 5886,7 8842,2 0,666 protein L31 RNA (guanine- 9-) methyltransfer ase domain 0,0087531 0,3604104 262,7 394,3 0,666 containing 1 integrator complex 0,0088883 0,3635583 346,3 520,1 0,666 subunit 3 integrator complex 0,0147287 0,4117033 110,9 166,5 0,666 subunit 9 Transcribed 0,0331216 0,4934061 27,1 40,7 0,666 locus MTERF domain 0,0400025 0,5087876 155,9 234,2 0,666 containing 1

DEAD (Asp- Glu-Ala-Asp) box 0,0426053 0,5127624 1247,3 1872,3 0,666 polypeptide 21 trinucleotide repeat 0,0465105 0,5200452 55,4 83,2 0,666 containing 6B

eukaryotic translation initiation factor 0,0025378 0,2760381 1653,7 2486,6 0,665 3, subunit F 0,0052396 0,3267775 40,5 60,9 0,665 KIAA1641 solute carrier family 38, 0,0074281 0,3504479 1286,2 1934,5 0,665 member 2

LUC7-like 2 (S. 0,0104708 0,3766691 102,3 153,8 0,665 cerevisiae) General transcription factor IIA, 1, 0,0108502 0,3819324 293,8 441,9 0,665 19/37kDa

methyl-CpG binding domain 0,0111089 0,3846606 41,4 62,3 0,665 protein 1 RAB13, member RAS oncogene 0,0130543 0,4026559 2106 3167,6 0,665 family zinc finger 0,017023 0,427416 82,7 124,3 0,665 protein 12 SEC11 homolog A (S. 0,0181888 0,4359169 1752,8 2634,6 0,665 cerevisiae) signal recognition particle receptor ('docking 0,0261751 0,4705663 1063,5 1598,5 0,665 protein') 0,0262602 0,4705663 54,4 81,8 0,665 protein phosphatase 1, regulatory (inhibitor) 0,030327 0,4842666 399,9 601,4 0,665 subunit 8

BMS1 homolog, ribosome assembly 0,0383132 0,5072367 200,9 302,2 0,665 protein (yeast) CDNA FLJ32587 fis, clone SPLEN200040 0,0402804 0,5097988 14,9 22,4 0,665 2 trinucleotide repeat 0,044276 0,5146068 60,7 91,3 0,665 containing 6B histidyl-tRNA synthetase 2, mitochondrial 0,0030771 0,2932482 245,5 369,6 0,664 (putative) G protein pathway 0,0238144 0,4633196 333,4 501,9 0,664 suppressor 2 hypothetical protein 0,0294036 0,4817626 232,2 349,5 0,664 HSPC111 chromosome 19 open reading frame 0,0359325 0,4990053 108,3 163 0,664 6 Nemo-like 0,0422758 0,5127624 63,6 95,8 0,664 kinase polymerase (RNA) II (DNA directed) polypeptide C, 0,0462476 0,519094 241,5 363,9 0,664 33kDa ribosomal 0,0026212 0,2797591 85,4 128,8 0,663 protein L31 DNA replication helicase 2 homolog 0,0037887 0,3114214 49,8 75,1 0,663 (yeast) ribosomal 0,0038443 0,3114214 6033,6 9097,1 0,663 protein L8 small nuclear ribonucleoprot ein D2 polypeptide 0,0066463 0,3412079 1576,7 2377,1 0,663 16.5kDa

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), 0,0092634 0,3687888 46,2 69,7 0,663 alpha 1 ubiquitin specific 0,0147743 0,4119489 52,5 79,2 0,663 peptidase 21 tripartite motif- 0,0148495 0,4121302 143,8 216,9 0,663 containing 39 N- acetyltransfera 0,0193901 0,4417307 144,7 218,3 0,663 se 10

chromosome 7 open reading 0,0346317 0,4968481 58,9 88,9 0,663 frame 31 RAB34, member RAS oncogene 0,0428387 0,5127624 594,3 896,4 0,663 family serum/glucoco rticoid regulated kinase family, member 3 /// chromosome 8 open reading 0,0445038 0,5147869 26,8 40,4 0,663 frame 44 SUMO1/sentri n/SMT3 specific 0,0450602 0,516331 48,4 73 0,663 peptidase 3 hypothetical protein 0,0038558 0,3114214 39,5 59,7 0,662 FLJ10038

small nucleolar RNA host gene (non-protein 0,0042868 0,3197234 17,8 26,9 0,662 coding) 9 CD44 molecule (Indian blood 0,0046203 0,3197234 2266,1 3422,6 0,662 group) family with sequence similarity 48, 0,0055476 0,3279506 123,7 186,9 0,662 member A steroid receptor RNA 0,0074968 0,3505421 311,7 470,6 0,662 activator 1 poly (ADP- ribose) polymerase family, member 0,0075967 0,3505421 169,2 255,6 0,662 6

transcription factor 7-like 2 (T-cell specific, 0,0098396 0,3706297 116,9 176,7 0,662 HMG-box) Transcribed 0,0115063 0,3883376 521,4 788 0,662 locus EH domain binding protein 0,0162807 0,4235618 26 39,3 0,662 1

small nucleolar RNA, H/ACA 0,0212248 0,4513673 18 27,2 0,662 box 72

Transmembran e 9 superfamily 0,0216544 0,4524803 43,3 65,4 0,662 member 1 CDNA FLJ23896 fis, clone 0,0246152 0,4667247 25,7 38,8 0,662 LNG15157 translocase of inner mitochondrial membrane 23 homolog 0,0266584 0,472096 309,8 468,2 0,662 (yeast) prolactin regulatory element 0,0419171 0,5123056 219,2 331,3 0,662 binding

RAD1 homolog 0,0446854 0,5155464 49,9 75,4 0,662 (S. pombe) nucleolar protein with MIF4G domain 0,0034731 0,3039332 99,1 150 0,661 1 glutamine-rich 0,0045361 0,3197234 304,6 460,7 0,661 1 ribosomal 0,0046326 0,3197234 5474,5 8284 0,661 protein S16 protein inhibitor of activated 0,0144673 0,4092451 48,1 72,8 0,661 STAT, 3 guanine nucleotide binding protein- like 3 0,0152137 0,415674 287,1 434,1 0,661 (nucleolar) ubiquitin- conjugating enzyme E2K (UBC1 homolog, 0,0337894 0,4946955 242,2 366,4 0,661 yeast) ENTH domain 0,034931 0,4971024 15,8 23,9 0,661 containing 1

zinc finger, CCHC domain 0,0386481 0,5072367 83,6 126,5 0,661 containing 2 CREB/ATF bZIP transcription 0,0440027 0,5143739 47,8 72,3 0,661 factor golgi SNAP receptor complex 0,0440501 0,5144565 212 320,8 0,661 member 1 polymerase (RNA) II (DNA directed) polypeptide C, 0,0498485 0,5252551 290,9 440,4 0,661 33kDa cytoplasmic linker associated 0,002706 0,2846641 92,2 139,8 0,66 protein 2 0,0063285 0,3385624 521,3 789,5 0,66 KIAA1012 mediator complex 0,0067286 0,3434229 101,3 153,5 0,66 subunit 23 DEAD (Asp- Glu-Ala-Asp) box 0,0174601 0,4305958 200,1 303,1 0,66 polypeptide 50 0,0211766 0,4508686 41,8 63,3 0,66 KIAA1731 centrosomal 0,0263603 0,470696 12,4 18,8 0,66 protein 55kDa

RAP1 interacting factor homolog 0,0356172 0,4984838 51,8 78,5 0,66 (yeast) pre-mRNA cleavage factor I, 59 kDa 0,0387831 0,5072367 473,2 716,5 0,66 subunit Bardet-Biedl 0,0103701 0,3766691 11,4 17,3 0,659 syndrome 12

zinc finger and BTB domain 0,0132368 0,4032981 12 18,2 0,659 containing 6 0,0138349 0,4051745 797,7 1210,1 0,659 matrin 3 translocase of inner mitochondrial membrane 9 homolog 0,0142638 0,4080969 88,4 134,1 0,659 (yeast) CDNA FLJ34250 fis, clone FCBBF400052 0,0153111 0,4157714 114,5 173,7 0,659 9

chromosome 4 open reading 0,0154658 0,4175766 16,6 25,2 0,659 frame 28 WD repeat 0,0164692 0,4242244 932,9 1415,5 0,659 domain 26

cytochrome P450, family 2, subfamily R, 0,0173936 0,4305249 101,4 153,8 0,659 polypeptide 1 0,0241628 0,4651764 19,7 29,9 0,659 Echinoderm microtubule associated 0,0242676 0,4657182 11,4 17,3 0,659 protein like 5 hypothetical protein 0,0261122 0,4702698 295,7 448,5 0,659 PRO2852

chromosome 1 open reading 0,0335372 0,493712 67,3 102,2 0,659 frame 66 isocitrate dehydrogenas e 3 (NAD+) 0,0373996 0,5048361 260,7 395,4 0,659 beta DEAH (Asp- Glu-Ala-His) box 0,0487729 0,5234842 171,4 260,2 0,659 polypeptide 30

hypothetical LOC399844 /// hypothetical LOC402483 /// hypothetical LOC653340 /// similar to FLJ45445 protein /// hypothetical protein LOC728797 /// hypothetical protein 0,0040755 0,316068 358,7 545,3 0,658 LOC729660

poly(A) binding protein interacting 0,0070978 0,3458012 758,9 1152,8 0,658 protein 2 Transcribed 0,0122042 0,3928661 20,4 31 0,658 locus zinc finger 0,0132478 0,4032981 20 30,4 0,658 protein 333 filamin A interacting 0,0142015 0,4080969 15,8 24 0,658 protein 1-like eukaryotic translation initiation factor 0,0343351 0,4961771 437,1 664,5 0,658 1 CCR4-NOT transcription complex, 0,0381699 0,5072367 143,1 217,4 0,658 subunit 1 cytochrome c, 0,0409423 0,5113922 20,2 30,7 0,658 somatic butyrophilin, subfamily 3, 0,0418647 0,5123056 53,6 81,4 0,658 member A3

ubiquitin protein ligase E3 component 0,0461749 0,5189014 261,9 397,9 0,658 n-recognin 1 E1A binding 0,0136479 0,4046068 84,1 128 0,657 protein p400 fusion (involved in t(12;16) in malignant 0,0249289 0,468375 496,5 755,5 0,657 liposarcoma) MON1 homolog B 0,0314884 0,4885675 138,5 210,9 0,657 (yeast) EF-hand domain family, 0,0339169 0,4949661 739,2 1124,6 0,657 member A1 CDNA clone IMAGE:516287 0,0395093 0,5080329 70,8 107,8 0,657 4

egf-like module containing, mucin-like, hormone 0,0024825 0,2753158 18,7 28,5 0,656 receptor-like 3 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 0,0027434 0,2846759 1519,8 2317,1 0,656 (subunit 9)

LUC7-like 2 (S. 0,0045211 0,3197234 204,1 311,1 0,656 cerevisiae) aminoadipate- semialdehyde dehydrogenas 0,0061304 0,3358513 37,2 56,7 0,656 e B-cell CLL/lymphoma 0,006325 0,3385624 76,6 116,8 0,656 10 0,0071788 0,3462686 228,8 348,7 0,656 CDNA FLJ36838 fis, clone ASTRO201142 0,0074509 0,3505421 19,3 29,4 0,656 6 ATG2 autophagy related 2 homolog B (S. 0,0082596 0,3568017 122,4 186,5 0,656 cerevisiae) high-mobility 0,0223743 0,4581196 32,6 49,7 0,656 group 20A

growth arrest- 0,032836 0,493025 80,4 122,5 0,656 specific 2 like 1 CLP1, cleavage and polyadenylatio n factor I subunit, homolog (S. 0,0345413 0,4967405 231,9 353,3 0,656 cerevisiae) CDNA FLJ36228 fis, clone THYMU200113 0,0347871 0,4971024 20,4 31,1 0,656 9 CDNA clone IMAGE:529988 0,0012849 0,2349562 50,7 77,4 0,655 8 Full-length cDNA clone CS0DI039YF1 2 of Placenta Cot 25- normalized of Homo sapiens 0,0060714 0,3342939 25,4 38,8 0,655 (human) heterogeneous nuclear ribonucleoprot 0,0110107 0,3829822 218,2 332,9 0,655 ein A0 family with sequence similarity 125, 0,0347259 0,4971024 222,2 339,3 0,655 member A CDNA FLJ34964 fis, clone NTONG20040 0,0390305 0,5080329 12,9 19,7 0,655 95 zinc finger 0,0392041 0,5080329 40,1 61,2 0,655 protein 700 methionyl aminopeptidas 0,0404129 0,5102945 126 192,5 0,655 e 1 splicing factor, arginine/serine- 0,0425235 0,5127624 924 1411,7 0,655 rich 3

A kinase (PRKA) anchor protein (yotiao) 0,0428658 0,5128503 128,6 196,2 0,655 9 interleukin enhancer binding factor 0,0430513 0,5129646 791,3 1207,3 0,655 2, 45kDa

polymerase (DNA directed) 0,0498287 0,5252551 352,6 538,7 0,655 kappa 0,0029289 0,2895505 283,4 433,4 0,654 KIAA0913 zinc finger, BED-type 0,0032343 0,2999829 300,9 460,2 0,654 containing 5 Sp3 transcription 0,0068752 0,3445477 209,7 320,6 0,654 factor

eukaryotic translation initiation factor 0,0104992 0,3766691 856,2 1310,1 0,654 3, subunit M

ISY1 splicing factor homolog 0,0109799 0,3829822 227,4 347,6 0,654 (S. cerevisiae)

three prime repair 0,0154988 0,4178097 415,8 636,1 0,654 exonuclease 1 A kinase (PRKA) anchor 0,0157445 0,419357 36,3 55,5 0,654 protein 10 ring finger and CHY zinc finger domain 0,0161741 0,4225126 152,6 233,3 0,654 containing 1 protein prenyltransfera se alpha subunit repeat 0,0181252 0,4355503 43,7 66,8 0,654 containing 1 Protein phosphatase 1, catalytic subunit, beta 0,0212874 0,4515035 1859,8 2841,9 0,654 isoform ubiquitin specific 0,0236653 0,4633196 48,2 73,7 0,654 peptidase 21

IKAROS family zinc finger 1 0,0274038 0,4727831 32,5 49,7 0,654 (Ikaros) neuroblastoma breakpoint family, member 11 /// neuroblastoma breakpoint family, member 20 /// neuroblastoma breakpoint family, member 10 /// neuroblastoma breakpoint family, member 8 /// CLIP-190- 0,0296041 0,4819829 960 1467,2 0,654 like chromosome 10 open reading frame 0,0339623 0,4949661 15,5 23,7 0,654 118 mitochondrial ribosomal 0,0394765 0,5080329 141,3 215,9 0,654 protein L46 CDNA FLJ34374 fis, clone FEBRA201750 0,0413685 0,5116636 73,2 111,9 0,654 2 CDNA clone IMAGE:479315 0,0467756 0,5203286 38,6 59 0,654 3 exosome 0,0046523 0,3197234 25,6 39,2 0,653 component 6 COP9 constitutive photomorphog enic homolog subunit 6 0,0170892 0,4279946 408,2 624,9 0,653 (Arabidopsis) homeodomain interacting protein kinase 0,0230164 0,4616748 353,8 541,6 0,653 1 splicing factor 3b, subunit 3, 0,0234366 0,4629012 204,5 313,1 0,653 130kDa mitochondrial ribosomal 0,0277966 0,4745266 265,8 406,9 0,653 protein S22 CDNA clone IMAGE:303323 0,0297673 0,4826515 34 52,1 0,653 16 F-box protein 0,0342364 0,4961507 309,9 474,7 0,653 28 0,0355909 0,4984838 256,2 392,5 0,653 lipin 2 0,0386093 0,5072367 27,5 42,1 0,653 KIAA0232

DEAH (Asp- Glu-Ala-His) box 0,0472899 0,521195 1133,8 1737 0,653 polypeptide 15 bolA homolog 0,0015709 0,2418041 13,3 20,4 0,652 1 (E. coli)

DALR anticodon binding domain 0,002224 0,2672586 24,5 37,6 0,652 containing 3 high mobility group nucleosomal binding domain 0,0037007 0,3103309 610,9 937,4 0,652 4 tuftelin interacting 0,0047105 0,3197234 23,4 35,9 0,652 protein 11

translocated promoter region (to activated MET 0,005729 0,3304939 391,5 600,2 0,652 oncogene) ring finger 0,0088343 0,3628966 70,9 108,7 0,652 protein 41 collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and 0,0135853 0,4041641 85,9 131,7 0,652 recessive) golgi SNAP receptor complex 0,0173414 0,4305249 141,6 217,1 0,652 member 1 choroideremia- like (Rab escort protein 0,0246724 0,4667247 10,3 15,8 0,652 2)

sirtuin (silent mating type information regulation 2 homolog) 1 (S. 0,0256829 0,4702698 146,2 224,2 0,652 cerevisiae) UBX domain 0,0269806 0,4727831 332,9 510,2 0,652 containing 2 nucleolar protein family A, member 2 (H/ACA small nucleolar 0,0435368 0,5138341 908,9 1393 0,652 RNPs)

chromosome 3 open reading 0,0439132 0,5143739 130,7 200,5 0,652 frame 19 CGG triplet repeat binding 0,0021299 0,2605196 669,1 1028,3 0,651 protein 1 C-type lectin domain family 0,0097116 0,3696189 531,5 817 0,651 7, member A pinin, desmosome associated 0,0117373 0,3891601 80,9 124,2 0,651 protein nucleolar protein with MIF4G domain 0,0122828 0,3928766 154,5 237,2 0,651 1 TATA element modulatory 0,0131387 0,402701 64,7 99,4 0,651 factor 1 phosphoinositi de-3-kinase, 0,0141709 0,408001 319,9 491,5 0,651 class 3 0,0163692 0,4235618 49,7 76,4 0,651 cullin 3 zinc finger, 0,0281656 0,4761728 120,3 184,9 0,651 MYM-type 2

COP9 constitutive photomorphog enic homolog subunit 2 0,0288308 0,4791082 906 1392,5 0,651 (Arabidopsis)

thrombospondi n, type I, domain containing 1 /// thrombospondi n, type I, domain containing 1 0,0497445 0,5252551 45,7 70,2 0,651 pseudogene RAB28, member RAS oncogene 0,0256069 0,4702698 45,3 69,7 0,65 family macrophage erythroblast attacher /// similar to macrophage erythroblast 0,0268979 0,4727831 216,2 332,4 0,65 attacher nitric oxide synthase interacting 0,0483075 0,5224951 154 237,1 0,65 protein THUMP domain 0,0043694 0,3197234 67,8 104,5 0,649 containing 2 NMDA receptor 0,0049274 0,3216637 108,6 167,4 0,649 regulated 1

interferon regulatory factor 2 binding 0,0068353 0,344282 150,4 231,8 0,649 protein 2 headcase homolog 0,0112838 0,3858197 380,6 586 0,649 (Drosophila) prefoldin 0,0122411 0,3928661 191,5 295 0,649 subunit 6 zinc finger 0,0153969 0,4167453 43,6 67,2 0,649 protein 565 protein disulfide isomerase family A, 0,0352439 0,4980167 79,6 122,6 0,649 member 5 ubiquitin specific 0,0365223 0,5009676 135,6 209 0,649 peptidase 47 3'- phosphoadeno sine 5'- phosphosulfate 0,0436023 0,5140487 1000,5 1541,8 0,649 synthase 1 BUD13 homolog (S. 0,0454627 0,5172371 86,9 134 0,649 cerevisiae) chromosome 18 open reading frame 0,047645 0,521195 105,5 162,6 0,649 1

chromosome 1 open reading 0,001584 0,2418041 15,8 24,4 0,648 frame 71 RUN domain 0,0016014 0,2418041 62,5 96,4 0,648 containing 1 eukaryotic translation initiation factor 0,0149866 0,4143327 1286,6 1985,3 0,648 3, subunit D chromosome 12 open reading frame 0,0161215 0,4213791 12,5 19,3 0,648 48 peptidylprolyl isomerase G 0,0171666 0,4285771 53 81,8 0,648 (cyclophilin G) E2F transcription 0,0175395 0,4319694 170,4 262,8 0,648 factor 6 HLA-B associated 0,0184696 0,4377222 1097,3 1692,9 0,648 transcript 1

excision repair cross- complementing rodent repair deficiency, complementati on group 3 (xeroderma pigmentosum group B complementing 0,0260005 0,4702698 151,8 234,4 0,648 )

unconventional SNARE in the ER 1 homolog 0,0265045 0,4717232 89,2 137,7 0,648 (S. cerevisiae) WW domain containing adaptor with 0,0273991 0,4727831 257,3 397,3 0,648 coiled-coil

ribosomal protein S6 kinase, 70kDa, 0,0286444 0,4779166 144,7 223,3 0,648 polypeptide 1 Quaking homolog, KH domain RNA binding 0,0369817 0,5025331 430,2 663,9 0,648 (mouse) high-mobility group protein 2- 0,0411567 0,5116636 471,1 726,5 0,648 like 1 DEAD/H (Asp- Glu-Ala- Asp/His) box polypeptide 0,0413484 0,5116636 124,2 191,6 0,648 26B F-box protein 0,0077383 0,3508222 34,3 53 0,647 28 ribosomal protein L18a /// similar to ribosomal protein L18a; 60S ribosomal 0,0093668 0,3687888 6272,2 9695,6 0,647 protein L18a nucleolar and coiled-body phosphoprotei 0,0110039 0,3829822 136,9 211,7 0,647 n 1

2-oxoglutarate and iron- dependent oxygenase domain 0,0207011 0,4485902 100,8 155,8 0,647 containing 1 Transcribed 0,022852 0,4610454 36,6 56,6 0,647 locus DEAD (Asp- Glu-Ala-Asp) box 0,0237482 0,4633196 428,1 662 0,647 polypeptide 1 hypothetical 0,0242882 0,4657509 136,5 211 0,647 LOC65996

Splicing factor, arginine/serine- rich 2, interacting 0,0281741 0,4761728 29,2 45,1 0,647 protein

Pvt1 oncogene homolog, MYC activator 0,028287 0,4764283 56,2 86,8 0,647 (mouse) CDNA FLJ42306 fis, clone TRACH200164 0,0364525 0,5004966 26,2 40,5 0,647 6 RAB40C, member RAS oncogene 0,040019 0,5087876 42 64,9 0,647 family RAE1 RNA export 1 homolog (S. 0,0407303 0,5112983 577,3 892,7 0,647 pombe) PDLIM1 interacting 0,0457277 0,5177385 31,2 48,2 0,647 kinase 1 like coiled-coil alpha-helical 0,0016317 0,2418041 24,1 37,3 0,646 rod protein 1 Transcribed 0,0087199 0,3604104 193,7 299,9 0,646 locus Transcribed locus, weakly similar to XP_519878.1 PREDICTED: similar to ubiquitin- conjugating enzyme E2 variant 1 isoform c; DNA- binding protein [Pan 0,0092136 0,3687841 47,9 74,1 0,646 troglodytes] ribosomal protein S4, Y- 0,0107731 0,3805034 2402,1 3719,2 0,646 linked 1

vacuolar protein sorting 37 homolog C 0,0175831 0,4322644 640,2 991,1 0,646 (S. cerevisiae)

signal-induced proliferation- associated 1 0,027254 0,4727831 67,4 104,4 0,646 like 2 SET domain 0,0385844 0,5072367 26,8 41,5 0,646 containing 5 Transcribed 0,0461621 0,5188965 66,9 103,6 0,646 locus THAP domain 0,0077928 0,3510054 14 21,7 0,645 containing 9

chromosome 9 open reading 0,0086697 0,3602917 127,4 197,4 0,645 frame 156

SRY (sex determining 0,0171213 0,428155 138,4 214,7 0,645 region Y)-box 6 mitochondrial translation optimization 1 homolog (S. 0,0344054 0,4962347 106,5 165,1 0,645 cerevisiae) chromosome 11 open reading frame 0,0409118 0,5113922 191,7 297,2 0,645 54 v-raf-1 murine leukemia viral oncogene 0,0022959 0,2707473 343,4 533,1 0,644 homolog 1

shugoshin-like 0,0059747 0,331305 17,4 27 0,644 2 (S. pombe) 0,0106033 0,3783524 18,3 28,4 0,644 KIAA1967

chromosome 7 open reading 0,0118819 0,3892408 484 751,6 0,644 frame 30 chromosome 9 open reading 0,0130757 0,4026559 124,9 194 0,644 frame 97

GDP-mannose pyrophosphory 0,0242021 0,4652389 182,6 283,5 0,644 lase B Transcribed 0,02583 0,4702698 76,2 118,4 0,644 locus

complement component 1, s 0,0273726 0,4727831 18,8 29,2 0,644 subcomponent TANK-binding 0,0274222 0,4727831 607,1 942,6 0,644 kinase 1 PRP31 pre- mRNA processing factor 31 homolog (S. 0,0322981 0,4914731 120,4 186,9 0,644 cerevisiae) zinc finger CCCH-type 0,0433135 0,5130413 160 248,6 0,644 containing 14 bridging 0,0450175 0,516331 191,8 297,8 0,644 integrator 3 golgi autoantigen, golgin 0,0488279 0,5234842 264,8 411,4 0,644 subfamily a, 5 ribosomal 3 0,0009875 0,2205294 4890 7602 0,643 protein L17 mitogen- activated protein kinase kinase kinase 0,0028659 0,288618 800,2 1244 0,643 2

MRNA; cDNA DKFZp547C07 2 (from clone DKFZp547C07 0,0036895 0,3102953 16 24,9 0,643 2) chromosome 10 open reading frame 0,0046535 0,3197234 30,5 47,4 0,643 28 Chromodomai n helicase DNA binding protein 0,0191839 0,4417307 37,6 58,5 0,643 2 ribonucleotide reductase M1 0,0200681 0,4476045 301,9 469,7 0,643 polypeptide 0,0203641 0,4485902 390,7 607,6 0,643 amyotrophic lateral sclerosis 2 0,021032 0,4498978 51,8 80,6 0,643 (juvenile) RNA U, small nuclear RNA export adaptor (phosphorylati 0,0216402 0,4524803 97,5 151,7 0,643 on regulated)

vacuolar protein sorting 37 homolog C 0,0286029 0,4776731 1124,4 1747,8 0,643 (S. cerevisiae) endoplasmic reticulum to nucleus 0,0291884 0,4812171 100,2 155,9 0,643 signaling 1

spleen tyrosine 0,0338209 0,4946955 500,9 779 0,643 kinase 0,0438119 0,5143739 52,7 81,9 0,643 utrophin

zinc finger and BTB domain 0,0015906 0,2418041 20,4 31,8 0,642 containing 24 Transcribed locus, moderately similar to XP_512041.1 PREDICTED: similar to Myosin regulatory light chain 2, nonsarcomeric (Myosin RLC) [Pan 0,0021294 0,2605196 45,2 70,4 0,642 troglodytes] 0,0032446 0,2999829 52,4 81,6 0,642 KIAA0423 endothelial differentiation, lysophosphatid ic acid G- protein- coupled 0,0042982 0,3197234 153,9 239,8 0,642 receptor, 2

lin-54 homolog 0,0048188 0,3211399 11,1 17,3 0,642 (C. elegans) chromosome 10 open reading frame 0,0088449 0,3630592 257,7 401,1 0,642 26 FGFR1 oncogene 0,009412 0,3688312 16,3 25,4 0,642 partner 2 Transcribed 0,0096023 0,3692024 26,5 41,3 0,642 locus arginyl-tRNA synthetase 2, 0,0271586 0,4727831 323 503,2 0,642 mitochondrial hypothetical gene supported by 0,028264 0,4764283 44,8 69,8 0,642 BC047417 N- acetyltransfera 0,0383793 0,5072367 962,5 1499,8 0,642 se 13 TH1-like 0,0387617 0,5072367 274,3 427,3 0,642 (Drosophila) ataxia telangiectasia 0,0397785 0,5087876 349,8 544,6 0,642 mutated ribonuclease P/MRP 30kDa 0,0468426 0,5205413 218,7 340,7 0,642 subunit 0,004134 0,3163535 122,9 191,6 0,641 CDKN2A interacting 0,0044747 0,3197234 69,2 108 0,641 protein MRNA full length insert cDNA clone EUROIMAGE 0,0208693 0,448736 31,3 48,8 0,641 1652049 ubiquitin specific 0,0236397 0,4633196 222,8 347,5 0,641 peptidase 48

chromosome 3 open reading 0,0271664 0,4727831 74,7 116,6 0,641 frame 19 PFTAIRE protein kinase 0,0298881 0,4826515 21,4 33,4 0,641 1 hypothetical gene supported by 0,0320574 0,4905509 120,5 188 0,641 BC036588 Werner 0,0349013 0,4971024 56,4 88 0,641 syndrome THO complex 0,0381999 0,5072367 140,8 219,6 0,641 5 ribosomal protein L7-like 0,0395278 0,5080329 545,4 851,5 0,641 1 brix domain 0,0016944 0,2418833 76,4 119,3 0,64 containing 2

eukaryotic translation initiation factor 0,002365 0,2714688 2590,3 4047,7 0,64 4A, isoform 2 Microcephalin 0,0080219 0,3545654 28,6 44,7 0,64 1 ankyrin repeat and KH domain containing 1 /// ANKHD1- 0,0108904 0,3819324 445,8 696,8 0,64 EIF4EBP3 RGP1 retrograde golgi transport homolog (S. 0,015236 0,415674 85,8 134,1 0,64 cerevisiae) coiled-coil domain 0,0382578 0,5072367 73,3 114,6 0,64 containing 95

Vesicle transport through interaction with t-SNAREs homolog 1A 0,0426575 0,5127624 45,6 71,2 0,64 (yeast) centromere 0,0450897 0,516331 16,2 25,3 0,64 protein K eukaryotic translation initiation factor 0,046157 0,5188965 601,9 940 0,64 4B ribosomal 134 0,0007507 0,2088164 4772,4 7464 0,639 protein L17 0,0073633 0,3497491 227,7 356,2 0,639 KIAA0241

inhibitor of kappa light polypeptide gene enhancer in B-cells, 0,0096609 0,3696189 67,3 105,4 0,639 kinase beta Janus kinase 2 (a protein tyrosine 0,0114651 0,3876349 763,4 1194,7 0,639 kinase)

NHP2 non- histone chromosome protein 2-like 1 0,0187091 0,4392874 737,8 1155,3 0,639 (S. cerevisiae) cell division cycle 20 homolog (S. 0,0230445 0,4616944 27,8 43,5 0,639 cerevisiae)

carboxylestera se 2 (intestine, 0,0295459 0,4819829 177,9 278,5 0,639 liver) ECSIT homolog 0,0326339 0,4928929 76,7 120,1 0,639 (Drosophila) translocase of inner mitochondrial membrane 23 homolog (yeast) /// translocase of inner mitochondrial membrane 23 homolog B 0,0419879 0,5123056 217 339,6 0,639 (yeast)

cylindromatosi s (turban tumor 0,0015704 0,2418041 235,1 368,6 0,638 syndrome) zinc finger protein 91 homolog 0,0079927 0,3545654 251,4 394,2 0,638 (mouse) tubulin, gamma complex associated 0,010309 0,3766691 25,7 40,3 0,638 protein 3 Transcribed 0,0118641 0,3891601 145,8 228,4 0,638 locus methyltransfer 0,0120578 0,3915788 70,9 111,2 0,638 ase like 3 hypothetical protein 0,013577 0,4041641 95,8 150,2 0,638 LOC25900 ribosomal 0,0160965 0,4211937 4684,3 7342,2 0,638 protein L18 activity- dependent neuroprotector 0,026902 0,4727831 239 374,7 0,638 homeobox Full-length cDNA clone CS0DF027YF1 7 of Fetal brain of Homo sapiens 0,0342836 0,4961507 55,6 87,1 0,638 (human) chromosome 1 open reading frame 119 /// similar to 0,0015912 0,2418041 624,3 980,4 0,637 K07F5.15 AT hook containing transcription 0,0035577 0,3039332 26 40,8 0,637 factor 1 tryptase 0,007259 0,3475357 51 80 0,637 alpha/beta 1 chromosome 19 open reading frame 0,0096949 0,3696189 46,9 73,6 0,637 40 CREB/ATF bZIP transcription 0,0118399 0,3891601 49,7 78 0,637 factor TBC1 domain family, member 0,0186123 0,4384436 295,4 463,9 0,637 23 CDNA FLJ12360 fis, clone MAMMA10023 0,0259791 0,4702698 12,8 20,1 0,637 56

DEAH (Asp- Glu-Ala-His) box 0,0262969 0,4705663 140 219,7 0,637 polypeptide 30 0,0399714 0,5087876 197,2 309,8 0,637 NDUFA12-like mediator complex 0,0443003 0,5146068 78,6 123,3 0,637 subunit 24 BCL2-like 12 178 0,0007516 0,2088164 55,1 86,7 0,636 (proline rich) polyhomeotic homolog 1 (Drosophila) /// similar to polyhomeotic 1- 0,0025206 0,2756013 176,7 277,9 0,636 like

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), 0,0027656 0,2846759 135,9 213,7 0,636 alpha 1 FSHD region 0,0036412 0,3077156 624,4 982,4 0,636 gene 1 histone cluster 0,0048462 0,3211399 62,7 98,6 0,636 1, H1c zinc finger, RAN-binding domain 0,0060654 0,3342939 155,1 244 0,636 containing 1 0,0103545 0,3766691 68,3 107,4 0,636 Ataxin 3

TSC22 domain family, member 0,0125474 0,3964301 85,8 135 0,636 3 pyruvate dehydrogenas e (lipoamide) 0,0132953 0,4038543 521,2 819,9 0,636 alpha 1 tripartite motif- 0,0135997 0,4041641 21,8 34,3 0,636 containing 23 NOL1/NOP2/S un domain family, member 0,0186384 0,4386516 79,7 125,4 0,636 4 origin recognition complex, subunit 2-like 0,0229174 0,4615134 52,5 82,6 0,636 (yeast)

PQ loop repeat 0,0253086 0,4702698 101,8 160,1 0,636 containing 2 0,0262015 0,4705663 47,4 74,5 0,636 transketolase (Wernicke- Korsakoff 0,0271807 0,4727831 1096,5 1724 0,636 syndrome) nuclear autoantigenic sperm protein (histone- 0,0278684 0,4745266 172,8 271,5 0,636 binding) basic helix- loop-helix domain containing, 0,0283139 0,4764735 595,8 936,4 0,636 class B, 3 poly(A) polymerase 0,0428231 0,5127624 420 660 0,636 alpha

TAF1 RNA polymerase II, TATA box binding protein (TBP)- associated 0,0474017 0,521195 91,6 144 0,636 factor, 250kDa transformation/ transcription domain- associated 83 0,0008482 0,2147006 226,6 357,1 0,635 protein TAF13 RNA polymerase II, TATA box binding protein (TBP)- associated 0,0126144 0,3972882 13,2 20,8 0,635 factor, 18kDa exportin 1 (CRM1 homolog, 0,0152224 0,415674 826,8 1301,1 0,635 yeast)

poly(A) binding protein interacting 0,0188144 0,4401921 856,3 1347,5 0,635 protein 2 v-crk sarcoma virus CT10 oncogene homolog 0,0200974 0,4476045 194,2 305,7 0,635 (avian)-like Transcribed 0,0323589 0,4917015 31,3 49,3 0,635 locus RNA binding motif protein 0,0053958 0,3274124 28,1 44,3 0,634 14 TATA element modulatory 0,005844 0,3307111 74,9 118,2 0,634 factor 1

0,0076914 0,3505421 85,5 134,8 0,634 synaptojanin 2 formin binding 0,0077937 0,3510054 517,6 816,4 0,634 protein 4 calcium channel, voltage- dependent, alpha 2/delta 0,0095859 0,3688312 77,4 122 0,634 subunit 4 CWF19-like 1, cell cycle control (S. 0,0200982 0,4476045 48,4 76,3 0,634 pombe) SEC63 homolog (S. 0,0272436 0,4727831 320 504,8 0,634 cerevisiae) BRCA2 region, mRNA sequence 0,038953 0,5080329 83,9 132,3 0,634 CG036

CDC5 cell division cycle 5- 0,0415111 0,5116908 261,7 413 0,634 like (S. pombe) nuclear receptor binding factor 2 pseudogene /// similar to nuclear receptor binding factor 0,0437749 0,5142657 11,8 18,6 0,634 2 FtsJ homolog 0,045972 0,5183695 77,7 122,5 0,634 2 (E. coli)

ribosomal protein S7 /// similar to 40S ribosomal 0,0016274 0,2418041 3199,1 5051,3 0,633 protein S7 (S8) Transcribed 0,0071882 0,3462686 236,2 373,4 0,633 locus

small optic lobes homolog 0,0079756 0,3545654 55,5 87,7 0,633 (Drosophila) programmed 0,0175988 0,4324559 94,5 149,2 0,633 cell death 11 structural maintenance of chromosomes 0,022973 0,461565 118 186,5 0,633 5 ubiquitin associated and SH3 domain 0,0232896 0,4625449 188,2 297,1 0,633 containing, B

Transcribed locus, strongly similar to XP_519898.1 PREDICTED: similar to DKFZP564O0 463 protein; HSPC064 protein [Pan 0,0245128 0,4660137 68,1 107,5 0,633 troglodytes] UBX domain 0,0295841 0,4819829 489,6 773,1 0,633 containing 2

zinc finger and BTB domain 0,0370963 0,5031712 201,6 318,6 0,633 containing 11

SMEK homolog 1, suppressor of mek1 0,0056083 0,3279506 169,4 267,9 0,632 (Dictyostelium) PHD finger 0,0141568 0,407925 77,4 122,4 0,632 protein 3 LSM3 homolog, U6 small nuclear RNA associated (S. 0,0203793 0,4485902 722,8 1142,9 0,632 cerevisiae) dedicator of 0,0273295 0,4727831 645 1020,3 0,632 cytokinesis 11

ADP- ribosylation factor GTPase activating 0,0334959 0,493712 917,6 1451,7 0,632 protein 3 SAR1 gene homolog A (S. 0,0389883 0,5080329 750,2 1186,6 0,632 cerevisiae) CDNA clone IMAGE:530354 0,042674 0,5127624 16 25,3 0,632 7 general transcription factor IIIC, polypeptide 2, 0,0047718 0,3199091 78,6 124,6 0,631 beta 110kDa ribosomal protein S2 /// hypothetical gene supported by AB082925; BC019021; NM_002952 /// similar to ribosomal protein S2 /// hypothetical 0,0050356 0,3240923 1986,6 3150,4 0,631 LOC645173 peroxisomal biogenesis 0,0236331 0,4633196 129,2 204,6 0,631 factor 16

peptide deformylase (mitochondrial) /// component of oligomeric golgi complex 0,0336187 0,4939808 87,7 138,9 0,631 8

chromosome 1 open reading 0,0104397 0,3766691 9,2 14,6 0,63 frame 150 Transcribed 0,0117493 0,3891601 21,5 34,1 0,63 locus

Ubiquitin protein ligase E3 component 0,021256 0,4515035 19,4 30,8 0,63 n-recognin 5 Synaptotagmin- 0,0234659 0,4629012 129,2 205,1 0,63 like 3 CDNA: FLJ21299 fis, clone 0,0320361 0,4904995 57 90,5 0,63 COL02041 0,0427611 0,5127624 80,6 128 0,63 Zinc finger 0,0013779 0,238971 33,4 53,1 0,629 protein 81 solute carrier family 27 (fatty acid transporter), 0,0043477 0,3197234 14,6 23,2 0,629 member 2 membrane- spanning 4- domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta 0,0116882 0,3891601 12,9 20,5 0,629 polypeptide) 0,0131533 0,402799 168,3 267,6 0,629 solute carrier family 25 (mitochondrial carrier, brain), 0,0158711 0,4196703 138,9 221 0,629 member 14 CCCTC- binding factor (zinc finger 0,0205774 0,4485902 213,7 339,8 0,629 protein)

A kinase (PRKA) anchor 0,0309878 0,4871817 126,9 201,7 0,629 protein 8

chromosome 2 open reading 0,0317295 0,4894884 11 17,5 0,629 frame 63 asparaginase 0,0343531 0,4961771 79,6 126,5 0,629 like 1

ADP- ribosylation 0,0364558 0,5004966 40,3 64,1 0,629 factor-like 13B ADP- ribosylation 0,0371643 0,5033337 242,1 384,6 0,629 factor 1 0,0380161 0,5071739 524,4 833,2 0,629 surfeit 4 RNA binding motif protein 89 0,0007609 0,2088164 135,9 216,4 0,628 33

centrosomal 0,0048265 0,3211399 60 95,5 0,628 protein 350kDa mannosidase, alpha, class 0,007505 0,3505421 49,6 79 0,628 2A, member 2 family with sequence similarity 110, 0,0081048 0,3561466 75,8 120,7 0,628 member A hypothetical protein 0,0145901 0,4106872 28,2 44,9 0,628 BC006136

chromosome X open reading 0,0204702 0,4485902 52,4 83,4 0,628 frame 15 kelch repeat and BTB (POZ) domain 0,0221085 0,4559722 33,6 53,5 0,628 containing 11 mitochondrial ribosomal 0,023852 0,4633196 202,1 321,7 0,628 protein S22 hypothetical protein FLJ22639 /// hypothetical protein 0,0252159 0,4702698 14 22,3 0,628 LOC728686 0,0304712 0,4849637 94,9 151,1 0,628 coilin zinc finger, AN1-type 0,0308594 0,4870313 1199 1909,1 0,628 domain 5 death effector domain 0,0425851 0,5127624 234,3 373,2 0,628 containing 2 regulatory factor X- associated ankyrin- containing 0,0468511 0,5205413 245,2 390,2 0,628 protein

chromosome 6 open reading 0,0041196 0,3163535 146 232,7 0,627 frame 106 Full length insert cDNA clone 0,004618 0,3197234 29,1 46,4 0,627 YP87D03 zinc finger 0,0051707 0,3263638 110,1 175,6 0,627 protein 43 0,0082039 0,3566213 33,6 53,6 0,627 oncostatin M Transcribed 0,0148179 0,4119489 39,2 62,5 0,627 locus

ribosomal protein S6 kinase, 90kDa, 0,0204394 0,4485902 623,6 994,3 0,627 polypeptide 3

tRNA nucleotidyl transferase, 0,020656 0,4485902 45,9 73,2 0,627 CCA-adding, 1 polyglutamine binding protein 0,035253 0,4980167 215,9 344,1 0,627 1 ESF1, nucleolar pre- rRNA processing protein, homolog (S. 0,0378099 0,5070433 109,6 174,7 0,627 cerevisiae)

TAF4 RNA polymerase II, TATA box binding protein (TBP)- associated 0,038445 0,5072367 72,9 116,2 0,627 factor, 135kDa ribosomal 0,002886 0,288618 1727,5 2758,9 0,626 protein L35a coiled-coil domain 0,0049206 0,3216637 8,7 13,9 0,626 containing 15 Transcribed 0,005183 0,3263638 25,1 40,1 0,626 locus DNA fragmentation factor, 45kDa, alpha 0,0064504 0,3395481 104,1 166,3 0,626 polypeptide SNW domain 0,0094691 0,3688312 274,6 439 0,626 containing 1

phosphatidylin ositol-specific phospholipase C, X domain 0,0100643 0,3745852 163,3 260,7 0,626 containing 1 CCR4-NOT transcription complex, 0,0108129 0,3811916 190,5 304,3 0,626 subunit 8

ORM1-like 1 0,014259 0,4080969 525,8 839,6 0,626 (S. cerevisiae) CCR4-NOT transcription complex, 0,0184093 0,4372409 110,1 175,9 0,626 subunit 8 C-type lectin domain family 0,0188814 0,4404183 529,7 845,6 0,626 2, member B glucosidase, beta (bile acid) 0,0220004 0,4549812 82 131 0,626 2 zinc finger 0,0257578 0,4702698 478,9 765,3 0,626 protein 655 AF4/FMR2 family, member 0,0274517 0,4727831 110,3 176,1 0,626 4

uridine monophosphat e synthetase (orotate phosphoribosyl transferase and orotidine- 5'- 0,0333661 0,493712 82,2 131,4 0,626 decarboxylase)

SERPINE1 mRNA binding 0,0362164 0,4996547 103,1 164,8 0,626 protein 1 potassium intermediate/s mall conductance calcium- activated channel, subfamily N, 0,0388185 0,5072367 485,4 775,1 0,626 member 4 tRNA methyltransfer ase 11 homolog (S. 0,0407956 0,5112983 105,1 167,8 0,626 cerevisiae) dual-specificity tyrosine-(Y)- phosphorylatio n regulated 0,0495477 0,5248641 44,1 70,4 0,626 kinase 2 exosome 0,0125381 0,3964301 107,4 171,8 0,625 component 3

LETM1 domain 0,0133734 0,4041641 165 264,1 0,625 containing 1 ADNP 0,0064619 0,3397158 370,4 593,5 0,624 homeobox 2

mutS homolog 0,0070982 0,3458012 226,7 363,3 0,624 6 (E. coli) PSMC3 interacting 0,0192882 0,4417307 44,5 71,3 0,624 protein

suppressor of var1, 3-like 1 0,0206807 0,4485902 71,9 115,2 0,624 (S. cerevisiae) Transcribed 0,0324804 0,4922023 33 52,9 0,624 locus RNA binding motif protein, X- 0,0390818 0,5080329 429,8 689,2 0,624 linked mediator complex 0,0430976 0,5129646 44,2 70,8 0,624 subunit 30 structural maintenance of chromosomes flexible hinge domain 0,0490751 0,5242466 376,4 603,4 0,624 containing 1 ribonuclease P/MRP 14kDa 0,0045922 0,3197234 130,1 208,9 0,623 subunit small nuclear ribonucleoprot ein polypeptides B 0,016571 0,4254648 1952,3 3135,7 0,623 and B1 chaperonin containing TCP1, subunit 0,0237645 0,4633196 1755 2818,9 0,623 4 (delta) RAE1 RNA export 1 homolog (S. 0,0263827 0,4709351 315,9 507,1 0,623 pombe) CD44 molecule (Indian blood 0,0340407 0,4951364 2054,5 3298,2 0,623 group) aminoadipate- semialdehyde dehydrogenas 0,0362595 0,5000646 55,6 89,3 0,623 e Stress- associated endoplasmic reticulum 0,0418245 0,5123056 42,3 67,9 0,623 protein 1 eukaryotic translation initiation factor 0,0036946 0,3102953 161,2 259,3 0,622 5 zinc finger 0,00676 0,3434229 191,3 307,8 0,622 protein 143 enolase 2 (gamma, 0,0071173 0,3458012 70,7 113,6 0,622 neuronal) RuvB-like 2 (E. 0,0198697 0,4467006 375,8 603,9 0,622 coli) ankyrin repeat and KH domain containing 1 /// ANKHD1- 0,025697 0,4702698 80,4 129,3 0,622 EIF4EBP3 COX17 cytochrome c oxidase assembly homolog (S. 0,0346262 0,4968481 696,5 1119,6 0,622 cerevisiae) integrin, alpha 0,0380228 0,5071739 18,9 30,4 0,622 7 CDNA FLJ34486 fis, clone HLUNG20042 0,0015426 0,2418041 13,3 21,4 0,621 17 CCR4-NOT transcription complex, 0,0049029 0,3216637 213,7 343,9 0,621 subunit 2 Transcribed 0,0090163 0,36462 38,1 61,4 0,621 locus Transcribed 0,0214509 0,4522939 30,3 48,8 0,621 locus

oxidative stress induced growth inhibitor family member 0,0236812 0,4633196 45,3 72,9 0,621 2 nucleolar 0,0253585 0,4702698 169,6 273,1 0,621 protein 8 Transcribed 0,0285544 0,4776731 12,6 20,3 0,621 locus

retinoid X 0,030317 0,4842483 71,9 115,7 0,621 receptor, alpha

centrosomal 0,0417389 0,5121871 39,6 63,8 0,621 protein 192kDa X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand- break rejoining; Ku autoantigen, 0,0441926 0,5146068 579,3 932,3 0,621 80kDa)

fibronectin type III domain 0,0493414 0,5248641 138,3 222,8 0,621 containing 3A proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional 0,0074352 0,3504479 1499,7 2419,9 0,62 peptidase 7) Kruppel-like 0,0083009 0,3568017 98,2 158,4 0,62 factor 2 (lung) PFTAIRE protein kinase 0,0107053 0,3795799 45,9 74 0,62 1 Transcribed 0,0170341 0,427416 27,7 44,7 0,62 locus trinucleotide repeat 0,0229875 0,461565 110,2 177,8 0,62 containing 6A brix domain 0,0237601 0,4633196 235 379,1 0,62 containing 1 speckle-type POZ protein- 0,0310442 0,4871817 114,4 184,5 0,62 like mitochondrial ribosomal 0,0333654 0,493712 823,9 1329,9 0,62 protein S24 translocation 0,039293 0,5080329 618,2 997,2 0,62 protein 1 zinc finger 0,0471969 0,521195 209,9 338,3 0,62 protein 266 Rho guanine nucleotide exchange factor (GEF) 0,0042433 0,3197234 67,1 108,4 0,619 10

suppressor of Ty 6 homolog 0,0048638 0,3211399 14,8 23,9 0,619 (S. cerevisiae) chromosome 12 open reading frame 0,0053149 0,3267775 33 53,3 0,619 29 DEAH (Asp- Glu-Ala-His) box 0,0073515 0,3497491 213,9 345,4 0,619 polypeptide 8 phosphohistidi ne 0,0081731 0,3563511 888,7 1436,1 0,619 phosphatase 1 additional sex combs like 2 0,0092456 0,3687888 49,8 80,5 0,619 (Drosophila)

phosphogluco 0,0137042 0,4046068 30 48,5 0,619 mutase 2-like 1

CDNA FLJ13495 fis, clone PLACE100442 5 /// Full-length cDNA clone CS0DI084YF1 3 of Placenta Cot 25- normalized of Homo sapiens 0,0305788 0,4857338 72,6 117,2 0,619 (human) 0,0313676 0,4885021 43,1 69,6 0,619 KIAA0406 zinc finger CCCH-type 0,0353762 0,4983242 415,2 670,8 0,619 containing 15 tripartite motif- containing 34 /// TRIM6- 0,0380879 0,5071739 63,8 103 0,619 TRIM34 protein associated with topoisomerase II homolog 1 0,0485936 0,523003 459,4 741,7 0,619 (yeast) forkhead box 0,0495368 0,5248641 626,3 1011,7 0,619 O3

methyl-CpG binding domain 0,002314 0,2709164 77,8 125,9 0,618 protein 1 transaldolase 1 /// chromosome 20 open reading frame 0,0040286 0,3147127 2555,7 4134,5 0,618 199 ubiquitin specific 0,0045123 0,3197234 197,3 319,5 0,618 peptidase 48 mediator complex 0,0122875 0,3928766 268,7 435 0,618 subunit 28 Transcribed 0,0223622 0,4580941 48,6 78,7 0,618 locus

chromosome 1 open reading 0,0257046 0,4702698 417,1 674,8 0,618 frame 52 non-SMC condensin I complex, 0,025714 0,4702698 37,4 60,5 0,618 subunit D2 M-phase phosphoprotei 0,0341869 0,4958007 57,9 93,7 0,618 n 1 Similar to SRR1-like 0,0346089 0,4968481 55,9 90,4 0,618 protein

transmembran e 4 L six family 0,0412261 0,5116636 10,5 17 0,618 member 1 HEAT repeat 192 0,0008716 0,2185997 51,3 83,2 0,617 containing 6 leucine zipper, down- regulated in 0,0010909 0,2213833 152,7 247,6 0,617 cancer 1-like zinc finger CCCH-type 0,0094952 0,3688312 544,6 882,3 0,617 containing 15 allograft inflammatory 0,0112512 0,3858197 698,9 1133,6 0,617 factor 1 solute carrier family 35 (UDP- N- acetylglucosa mine (UDP- GlcNAc) transporter), 0,011826 0,3891601 52,2 84,6 0,617 member A3 CDNA clone IMAGE:527738 0,0120174 0,3913349 10,3 16,7 0,617 0 allograft inflammatory 0,0167448 0,4260897 551 892,8 0,617 factor 1 prostaglandin E receptor 2 (subtype EP2), 0,0181879 0,4359169 162,1 262,8 0,617 53kDa dolichyl- phosphate (UDP-N- acetylglucosa mine) N- acetylglucosa minephosphotr ansferase 1 (GlcNAc-1-P 0,0189725 0,4406633 216 350,2 0,617 transferase) family with sequence similarity 73, 0,0230967 0,4617888 32,4 52,5 0,617 member A butyrophilin, subfamily 3, 0,0244998 0,4660137 58,2 94,4 0,617 member A1 mitochondrial ribosomal 0,0263049 0,4705663 22,6 36,6 0,617 protein S11 ZXD family 0,0269914 0,4727831 75,5 122,3 0,617 zinc finger C homeodomain interacting protein kinase 0,0288546 0,4792123 241,4 391 0,617 1 RNA binding motif protein 0,0422309 0,5127624 225,4 365,6 0,617 15

protein phosphatase 2, regulatory subunit B', 0,0061844 0,3366906 198,2 321,9 0,616 epsilon isoform YTH domain 0,0076477 0,3505421 443,5 719,4 0,616 containing 1 zinc finger 0,0092357 0,3687888 31,4 51 0,616 protein 805 isocitrate dehydrogenas e 3 (NAD+) 0,0135044 0,4041641 521,1 846,6 0,616 beta MRNA; cDNA DKFZp686F09 227 (from clone DKFZp686F09 0,0156482 0,4187789 31,3 50,8 0,616 227) isocitrate dehydrogenas e 3 (NAD+) 0,0160208 0,4211937 480,7 780,3 0,616 beta

small nucleolar RNA host gene (non-protein 0,0223403 0,4580941 48,6 78,9 0,616 coding) 7 E2F- associated phosphoprotei 0,0476878 0,521195 103,7 168,4 0,616 n ribosomal 0,0049179 0,3216637 4521,9 7356,8 0,615 protein S6 ubiquitin specific 0,0066821 0,3424028 39 63,4 0,615 peptidase 21 solute carrier family 38, 0,0101909 0,3757604 802,7 1304,6 0,615 member 2 steroid receptor RNA 0,0106878 0,3795799 196,2 319,1 0,615 activator 1 chromosome 13 open reading frame 0,0142018 0,4080969 34,4 55,9 0,615 34 synovial sarcoma translocation gene on chromosome 0,0256008 0,4702698 64,1 104,3 0,615 18-like 1 CDNA FLJ46538 fis, clone THYMU30378 0,0316497 0,4892284 280,3 456,1 0,615 27 polo-like kinase 3 0,0417483 0,5121871 205,2 333,9 0,615 (Drosophila) kelch repeat and BTB (POZ) domain 0,0439669 0,5143739 13,1 21,3 0,615 containing 7 ribosomal protein L22- 0,0440053 0,5143739 258,5 420,3 0,615 like 1 ribosomal 0,0023304 0,2709605 3292,1 5362,1 0,614 protein L35 pumilio homolog 2 0,0032481 0,2999829 202,7 330,1 0,614 (Drosophila) chromosome 12 open reading frame 0,0092338 0,3687888 119,9 195,2 0,614 43 Mitochondrial ribosomal 0,0115496 0,3885321 13,7 22,3 0,614 protein L39

NADH dehydrogenas e (ubiquinone) 1 alpha subcomplex, 0,0123796 0,3951282 891,4 1450,7 0,614 12 asparagine- linked glycosylation 9 homolog (S. cerevisiae, alpha- 1,2- mannosyltransf 0,0380426 0,5071739 39,7 64,7 0,614 erase) deoxynucleotid yltransferase, terminal, interacting 0,0420241 0,5123056 235,5 383,8 0,614 protein 1

transmembran 0,0422224 0,5127624 74,8 121,8 0,614 e protein 161B bromodomain PHD finger transcription 0,0016768 0,2418041 26 42,4 0,613 factor Transcribed 0,0049598 0,3216637 134,4 219,4 0,613 locus AT hook containing transcription 0,0054434 0,3274124 88,9 145,1 0,613 factor 1 nuclear fragile X mental retardation protein interacting 0,0206693 0,4485902 144,9 236,2 0,613 protein 2 cytoplasmic linker associated 0,0290662 0,4809911 55,5 90,6 0,613 protein 2

signal recognition 0,0337233 0,4946955 921,2 1503,9 0,613 particle 72kDa T cell receptor beta variable 19 /// T cell receptor beta variable 7-2 /// T cell receptor beta variable 5- 4 /// T cell receptor beta variable 3-1 /// T cell receptor beta constant 0,0425278 0,5127624 24,5 40 0,613 1 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 0,0046814 0,3197234 269 439,7 0,612 (yeast) zinc finger, FYVE domain 0,0067805 0,3435809 163,9 268 0,612 containing 20

SPT2, Suppressor of Ty, domain containing 1 0,0072191 0,3465358 43,1 70,4 0,612 (S. cerevisiae) ribonuclease 0,0074222 0,3504479 291,7 476,4 0,612 H1 0,0121551 0,3928661 297,5 486,1 0,612 zinc finger, HIT 0,0121916 0,3928661 17,8 29,1 0,612 type 4 Family with sequence similarity 120A opposite 0,0157077 0,419239 45,9 75 0,612 strand Smith-Magenis syndrome chromosome region, candidate 7- 0,0173194 0,4305249 147,5 241 0,612 like zinc finger 0,0274773 0,4727831 206,3 336,9 0,612 protein 295

GA binding protein transcription factor, alpha 0,0381787 0,5072367 75,9 124 0,612 subunit 60kDa cytochrome P450, family 19, subfamily A, polypeptide 0,039528 0,5080329 10,9 17,8 0,612 1 tripartite motif- 0,003145 0,2971525 11,8 19,3 0,611 containing 23 dishevelled, dsh homolog 1 (Drosophila) /// similar to dishevelled 1 0,0055651 0,3279506 116,7 191 0,611 isoform a hypothetical protein 0,0066261 0,3412079 136,1 222,8 0,611 FLJ31306 kelch-like 20 0,0077043 0,3505421 84,1 137,6 0,611 (Drosophila)

leukocyte immunoglobuli n-like receptor, subfamily B (with TM and ITIM domains), 0,008238 0,3566213 968,9 1586,1 0,611 member 1 solute carrier family 38, 0,0095849 0,3688312 746,8 1222,4 0,611 member 2

nucleotide binding protein 1 (MinD homolog, E. 0,0141608 0,407925 328,4 537,5 0,611 coli)

Homo sapiens, clone IMAGE:52184 0,0147777 0,4119489 44,3 72,5 0,611 12, mRNA ubiquitin specific 0,0213666 0,451823 84,5 138,4 0,611 peptidase 3 Transcribed 0,0277784 0,4745266 11,8 19,3 0,611 locus leucyl-tRNA 0,0477331 0,521195 525,7 860,8 0,611 synthetase CDNA FLJ14125 fis, clone MAMMA10025 0,0044914 0,3197234 81,5 133,5 0,61 45 hypothetical protein 0,0050444 0,3240923 260,3 426,4 0,61 LOC154092 peptidyl-tRNA 0,0060265 0,3324913 251 411,4 0,61 hydrolase 2 0,0065677 0,3412079 86,5 141,7 0,61 KIAA1468 REST 0,0160539 0,4211937 188,1 308,4 0,61 corepressor 1 YY1 transcription 0,0202094 0,4480026 248,1 406,9 0,61 factor 0,0256092 0,4702698 72,3 118,5 0,61 transforming growth factor beta regulator 0,0432921 0,5130413 606,1 993,3 0,61 1 keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et 0,0490579 0,5242466 342,2 561,1 0,61 plantaris) apoptotic peptidase activating 0,0043875 0,3197234 35,7 58,6 0,609 factor 1 golgi autoantigen, golgin 0,0055168 0,3279506 55,2 90,7 0,609 subfamily a, 1

LysM, putative peptidoglycan- binding, domain 0,0061989 0,3366906 77 126,4 0,609 containing 3

chromosome 1 open reading 0,0093641 0,3687888 218,2 358 0,609 frame 128 tRNA phosphotransf 0,010137 0,3752474 107,3 176,2 0,609 erase 1 cell division cycle 2-like 1 (PITSLRE proteins) /// cell division cycle 2- like 2 (PITSLRE 0,0257129 0,4702698 144,9 237,8 0,609 proteins) ubiquitin specific 0,025879 0,4702698 58 95,3 0,609 peptidase 30 MYST histone acetyltransfera se (monocytic 0,0306734 0,4862003 68,2 112 0,609 leukemia) 4 MORC family CW-type zinc 0,0309099 0,4870313 76,6 125,8 0,609 finger 2 huntingtin interacting 0,0393698 0,5080329 32,3 53 0,609 protein 1 zinc finger protein 106 homolog 0,0425404 0,5127624 259,1 425,5 0,609 (mouse) mitochondrial ribosomal 0,0460164 0,5183695 159,7 262,1 0,609 protein L44 transaldolase 1 /// chromosome 20 open reading frame 0,002039 0,2580609 1818,6 2990,2 0,608 199

caspase recruitment domain family, 0,0044629 0,3197234 63,1 103,7 0,608 member 8 transforming growth factor beta regulator 0,0107036 0,3795799 234,3 385,2 0,608 1 translocase of outer mitochondrial membrane 20 homolog 0,0138019 0,4051745 930,5 1530,6 0,608 (yeast) PHD finger protein 20-like 0,0190336 0,4414137 89,4 147 0,608 1 ERGIC and 0,0216014 0,4524803 173,3 285,2 0,608 golgi 2

Homo sapiens, clone IMAGE:29002 0,0238507 0,4633196 18 29,6 0,608 05, mRNA ubiquitin-like modifier activating 0,0304998 0,4851158 118,8 195,4 0,608 enzyme 5 optic atrophy 1 (autosomal 0,0308841 0,4870313 75,1 123,5 0,608 dominant) poly(A) polymerase 0,0322009 0,4912811 615,2 1011,2 0,608 alpha eukaryotic translation initiation factor 179 0,0006404 0,1980347 2098 3455,7 0,607 3, subunit E family with sequence similarity 62 (C2 domain containing) 199 0,0007224 0,2084556 210,5 346,8 0,607 member B ribosomal 0,0012387 0,2288038 2571,1 4234 0,607 protein L5

leukocyte immunoglobuli n-like receptor, subfamily B (with TM and ITIM domains), 0,0076405 0,3505421 781 1287 0,607 member 4

Protein phosphatase 2, regulatory subunit B', 0,0090049 0,3644285 60,4 99,5 0,607 epsilon isoform Transcribed 0,0100128 0,3736859 29 47,8 0,607 locus polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa pseudogene /// DNA directed RNA polymerase II polypeptide J- related /// RPB11b2 0,0133721 0,4041641 198,3 326,8 0,607 protein SEC63 homolog (S. 0,0185861 0,4382676 197,9 326 0,607 cerevisiae) RAB34, member RAS oncogene 0,0259551 0,4702698 594,9 980,2 0,607 family

Transcribed locus, strongly similar to NP_006451.1 HMBA- inducible [Homo 0,0283395 0,4766109 67,1 110,5 0,607 sapiens] CASP8 associated 0,0396547 0,5084647 55,4 91,3 0,607 protein 2 0,0425789 0,5127624 121,8 200,6 0,607 Dmx-like 2 Transcribed 0,0458034 0,5177385 301,3 496,1 0,607 locus ribosomal 99 0,0004655 0,1940962 4637,5 7650,2 0,606 protein L15 INO80 complex homolog 1 (S. 0,0054979 0,3279506 111,4 183,9 0,606 cerevisiae) protein kinase C substrate 0,0059668 0,331305 280,6 463,4 0,606 80K-H thioredoxin domain containing 4 (endoplasmic 0,0235477 0,4633196 28,5 47 0,606 reticulum) Transcribed 0,0344713 0,4962541 93,9 154,9 0,606 locus Transcribed 0,0490267 0,5241562 9,7 16 0,606 locus 0,0030375 0,2916576 404,7 668,7 0,605 0,0048225 0,3211399 606,9 1003,5 0,605 importin 7 zinc finger, DHHC-type 0,0087477 0,3604104 314 519 0,605 containing 17 splicing factor, arginine/serine- 0,0150728 0,4143327 517,4 854,7 0,605 rich 6

protein phosphatase 2 (formerly 2A), regulatory subunit B'', 0,019104 0,4414671 443,6 733,2 0,605 gamma CSE1 chromosome segregation 1- 0,0262602 0,4705663 718,8 1188,3 0,605 like (yeast) zinc finger, DHHC-type 0,0415731 0,511693 122 201,7 0,605 containing 4 casein kinase 0,0015676 0,2418041 213,2 352,7 0,604 1, alpha 1

signal recognition 0,0041516 0,3163535 897,3 1485,8 0,604 particle 72kDa RNA-binding region (RNP1, RRM) 0,0045787 0,3197234 99,4 164,5 0,604 containing 3 0,0063573 0,3392834 102,9 170,3 0,604 KIAA0776 CTD (carboxy- terminal domain, RNA polymerase II, polypeptide A) small phosphatase 0,0084659 0,3591295 22,6 37,4 0,604 like 2 WW domain binding protein 0,0098437 0,3706297 223,8 370,6 0,604 11 tubulin, alpha 0,0163686 0,4235618 356,3 590,1 0,604 4a THAP domain containing 4 /// similar to THAP domain- containing 0,0243014 0,4657509 107,1 177,2 0,604 protein 4 zinc finger, RAN-binding domain 0,0245237 0,4660137 369,1 610,8 0,604 containing 2

G protein- coupled receptor kinase 0,0332968 0,493712 75,6 125,2 0,604 interactor 2

small inducible cytokine subfamily E, member 1 (endothelial monocyte- 0,0350941 0,4973483 443,6 734,1 0,604 activating) retinoblastoma binding protein 0,0394861 0,5080329 16,9 28 0,604 9 frequently rearranged in advanced T- cell 0,0023342 0,2709605 17,5 29 0,603 lymphomas Armadillo repeat containing, X- 0,0037541 0,3114214 16,7 27,7 0,603 linked 4 CDNA FLJ33993 fis, clone DFNES200775 0,0046711 0,3197234 27,2 45,1 0,603 7 mitochondrial ribosomal 0,0124701 0,3963969 123 204 0,603 protein S31 AHNAK 0,0131236 0,4026559 112,1 185,8 0,603 nucleoprotein 0,0131603 0,402799 263,3 436,7 0,603 syntaxin 16 DIP2 disco- interacting protein 2 homolog B 0,0233154 0,4626778 14,1 23,4 0,603 (Drosophila) Transcribed 0,035827 0,498925 14,1 23,4 0,603 locus

TAR DNA 0,0415538 0,5116908 66 109,4 0,603 binding protein small VCP/p97- interacting 14 0,0010051 0,2205294 13,3 22,1 0,602 protein RAD21 homolog (S. 0,003241 0,2999829 396,9 658,8 0,602 pombe) tetratricopeptid e repeat 0,003828 0,3114214 143,4 238,1 0,602 domain 4 ganglioside induced differentiation associated 0,0041877 0,3171226 170,6 283,2 0,602 protein 2 tripartite motif- 0,0082133 0,3566213 127,1 211,2 0,602 containing 37 zinc finger 0,0162462 0,4234003 32 53,2 0,602 protein 331 protein C receptor, endothelial 0,0234426 0,4629012 10 16,6 0,602 (EPCR) Transcribed 0,0328496 0,493025 18 29,9 0,602 locus CHK2 checkpoint homolog (S. 0,0420412 0,5123056 73,6 122,2 0,602 pombe) cleavage stimulation factor, 3' pre- RNA, subunit 0,0020084 0,2571646 45,2 75,2 0,601 1, 50kDa

similar to large subunit ribosomal protein L36a /// 0,0041841 0,3171226 795,9 1324,1 0,601 hCG1789827 0,0045943 0,3197234 54,2 90,2 0,601 proline rich 14 0,00564 0,3288602 1204,4 2004,7 0,601 t-complex 1 TIA1 cytotoxic granule- associated RNA binding 0,0059137 0,3307111 81,6 135,8 0,601 protein-like 1 CCR4-NOT transcription complex, 0,0068581 0,344282 42 69,9 0,601 subunit 6-like zinc finger, 0,0098268 0,3706297 46,4 77,2 0,601 MYM-type 2 0,0183896 0,4370198 477,1 793,6 0,601 RAB28, member RAS oncogene 0,0339643 0,4949661 132,6 220,5 0,601 family

coiled-coil- helix-coiled-coil- helix domain 0,0360848 0,4990985 80,8 134,4 0,601 containing 4 poly (ADP- ribose) polymerase family, member 0,0370306 0,5029652 362,3 602,9 0,601 9 egl nine homolog 3 (C. 0,0404454 0,5103513 51,7 86 0,601 elegans) hypothetical protein 0,0439466 0,5143739 11,3 18,8 0,601 FLJ12078

stomatin 0,0455576 0,5172371 191,7 318,8 0,601 (EPB72)-like 2

polymerase (DNA directed), delta 1, catalytic subunit 0,0462283 0,519094 222,7 370,3 0,601 125kDa methylenetetra hydrofolate dehydrogenas e (NADP+ dependent) 2- 0,005898 0,3307111 16,8 28 0,6 like

heterogeneous nuclear ribonucleoprot ein U (scaffold attachment 0,0084041 0,3576553 73,6 122,7 0,6 factor A) 0,0162393 0,4234003 29,8 49,7 0,6 chromosome 10 open reading frame 0,0188551 0,4401921 89,7 149,6 0,6 137 HtrA serine 0,0231 0,4617888 123 205,1 0,6 peptidase 2 zinc finger 0,0277938 0,4745266 58,7 97,9 0,6 protein 354A zinc finger 0,0364464 0,5004966 83,3 138,9 0,6 protein 12

phosphatidylet hanolamine N- methyltransfer 0,0394395 0,5080329 114,6 190,9 0,6 ase family with sequence similarity 98, 0,0403857 0,5101686 84,6 141 0,6 member B

DEAD (Asp- Glu-Ala-Asp) box 0,0412267 0,5116636 241,8 402,7 0,6 polypeptide 18

chromosome 1 open reading 0,0437302 0,5141825 199,2 331,9 0,6 frame 31 synovial apoptosis inhibitor 1, 0,0053671 0,3267775 113,1 188,8 0,599 synoviolin heterogeneous nuclear ribonucleoprot 0,0068588 0,344282 54,9 91,6 0,599 ein C (C1/C2)

Splicing factor, arginine/serine- 0,0116865 0,3891601 210,3 351,2 0,599 rich 15 RuvB-like 2 (E. 0,0193753 0,4417307 277,2 462,4 0,599 coli) Transcribed 0,0335603 0,4937862 115,5 192,7 0,599 locus zinc finger, 0,0013853 0,238971 34,7 58 0,598 MYM-type 6

3-oxoacyl-ACP synthase, 0,0024318 0,2726804 57,3 95,8 0,598 mitochondrial

Transcribed locus, strongly similar to XP_001101634 .1 PREDICTED: similar to tripartite motif- containing 25 [Macaca 0,0095468 0,3688312 163,8 274 0,598 mulatta]

eukaryotic translation initiation factor 4E binding protein 3 /// ANKHD1- 0,0235233 0,4632294 214,5 358,9 0,598 EIF4EBP3 Transcribed 0,0349608 0,4971024 15,9 26,6 0,598 locus

FK506 binding protein 4, 0,0398383 0,5087876 93,2 155,9 0,598 59kDa mitochondrial ribosomal 0,0488413 0,5235048 391,2 653,7 0,598 protein L23

ribosomal RNA processing 12 homolog (S. 0,0016313 0,2418041 75,4 126,3 0,597 cerevisiae) muskelin 1, intracellular mediator containing 0,0016493 0,2418041 75,5 126,4 0,597 kelch motifs SNF1-like 0,0016835 0,2418041 86,8 145,4 0,597 kinase 2 transaldolase 1 /// chromosome 20 open reading frame 0,0024021 0,2720759 1677,4 2810,4 0,597 199 replication factor C (activator 1) 1, 0,0024338 0,2726804 87 145,8 0,597 145kDa

transcription factor 7-like 2 (T-cell specific, 0,0048207 0,3211399 425 711,4 0,597 HMG-box) calpain 2, (m/II) large 0,0051936 0,3263909 1585,3 2653,6 0,597 subunit Transcribed 0,0093068 0,3687888 32,4 54,3 0,597 locus 0,0170235 0,427416 72,9 122,1 0,597 thymopoietin peptidylprolyl isomerase H 0,0189715 0,4406633 330,3 553 0,597 (cyclophilin H) Casein kinase 0,025043 0,4692944 267,5 448,1 0,597 1, alpha 1 Transcribed 0,0407736 0,5112983 21,6 36,2 0,597 locus 0,0471134 0,521195 23 38,5 0,597 Transcribed locus, moderately similar to XP_00109120 8.1 PREDICTED: hypothetical protein [Macaca 0,0019009 0,2536814 180,5 303,1 0,596 mulatta]

methyltransfer ase 11 domain 0,002407 0,2720759 279,2 468,2 0,596 containing 1

heterogeneous nuclear ribonucleoprot ein U (scaffold attachment 0,0042638 0,3197234 21,4 35,9 0,596 factor A) Lyrm7 homolog 0,0049648 0,3216637 34 57 0,596 (mouse)

NMDA receptor 0,0075587 0,3505421 20,4 34,2 0,596 regulated 1-like GA binding protein transcription factor, alpha 0,0102379 0,3757604 36,2 60,7 0,596 subunit 60kDa 0,0347177 0,4971024 122,7 205,9 0,596 Transcribed 0,0356599 0,4984838 42,7 71,6 0,596 locus

zinc finger and BTB domain 0,0459353 0,5183695 170,1 285,5 0,596 containing 1

RAS protein 0,048926 0,523967 48,2 80,9 0,596 activator like 2 Ribosomal 47 0,0009029 0,2205071 45,1 75,8 0,595 protein L37 0,0013347 0,2369309 72,9 122,6 0,595 PRO1412 high mobility group nucleosomal binding domain 0,0076876 0,3505421 470,8 791,6 0,595 4 hypothetical protein 0,0120466 0,3915788 123,9 208,3 0,595 FLJ31306 mediator complex 0,0128753 0,4013438 584,7 981,9 0,595 subunit 1 neuroblastoma breakpoint family, member 15 /// neuroblastoma breakpoint family, member 10 /// neuroblastoma breakpoint family, member 8 /// neuroblastoma breakpoint family, member 16 /// hypothetical protein 0,0148243 0,4119489 1338,3 2247,5 0,595 LOC728980

SMEK homolog 2, suppressor of mek1 0,0160942 0,4211937 132,3 222,3 0,595 (Dictyostelium)

CXXC finger 1 0,021757 0,4524803 102,6 172,5 0,595 (PHD domain) CDNA FLJ38469 fis, clone FEBRA202189 0,0270171 0,4727831 61,5 103,3 0,595 2 hypothetical protein 0,0360571 0,4990491 22 37 0,595 LOC284757 0,0046992 0,3197234 180,1 303 0,594 KIAA0907 0,0049491 0,3216637 1262,9 2127,5 0,594 cell growth regulator with ring finger 0,0102246 0,3757604 119,7 201,4 0,594 domain 1 0,0251402 0,4697677 1817,3 3060,4 0,594 jun oncogene tripartite motif- containing 34 /// TRIM6- 0,0274757 0,4727831 232,7 391,7 0,594 TRIM34 diacylglycerol kinase, alpha 0,037633 0,50642 113,9 191,9 0,594 80kDa

DEAD (Asp- Glu-Ala-Asp) box 0,0392031 0,5080329 116,1 195,5 0,594 polypeptide 10 coiled-coil domain 0,0449748 0,516331 144,7 243,6 0,594 containing 84 forkhead box 0,0054349 0,3274124 332,5 560,8 0,593 O3 RANBP2-like and GRIP domain containing 5 /// RANBP2-like and GRIP domain containing 8 /// RANBP2-like and GRIP domain 0,0055252 0,3279506 200,7 338,2 0,593 containing 6 Farnesyltransf erase, CAAX 0,0129261 0,401446 14,6 24,6 0,593 box, beta AT rich interactive domain 2 (ARID, RFX- 0,0158098 0,4196703 74,7 126 0,593 like) chromosome 12 open reading frame 0,022226 0,4570164 240,4 405,5 0,593 31

Splicing factor, arginine/serine- 0,0273364 0,4727831 12,7 21,4 0,593 rich 11

NADH dehydrogenas e (ubiquinone) 1 alpha subcomplex, 5, 0,0311279 0,4879352 11,5 19,4 0,593 13kDa eukaryotic translation initiation factor 0,0312578 0,488431 765 1290,8 0,593 4B kelch repeat and BTB (POZ) domain 0,0392616 0,5080329 160,1 269,8 0,593 containing 2

IMP3, U3 small nucleolar ribonucleoprot ein, homolog 0,0427864 0,5127624 100 168,5 0,593 (yeast)

glutamate receptor, ionotropic, N- methyl D- aspartate-like 1A /// GRINL1A combined protein /// similar to glutamate receptor, ionotropic, N- methyl D- aspartate-like 0,0443967 0,5146943 86,3 145,5 0,593 1A isoform 1 ADNP 0,0066338 0,3412079 167,9 283,8 0,592 homeobox 2 WD repeat 0,0091855 0,3683909 26,7 45,1 0,592 domain 5

BUB1 budding uninhibited by benzimidazole s 1 homolog 0,0135814 0,4041641 16,7 28,2 0,592 (yeast) WD repeat 0,0146302 0,4109237 108,6 183,6 0,592 domain 73 RNA polymerase II associated 0,0267517 0,4727831 61,6 104,1 0,592 protein 3 chromosome 10 open reading frame 0,0330495 0,4934061 37,8 63,8 0,592 54 RNA binding motif protein 0,0336848 0,4945732 23,5 39,7 0,592 12B

Numb homolog 0,0399697 0,5087876 122 206,2 0,592 (Drosophila) RIO kinase 1 0,0016781 0,2418041 94,6 160 0,591 (yeast) zinc finger 0,003459 0,3039332 30,5 51,6 0,591 protein-like 1 MRNA; cDNA DKFZp566C09 3 (from clone DKFZp566C09 0,0062909 0,3375417 47,6 80,5 0,591 3) TGF beta- inducible nuclear protein 0,0119874 0,3910796 1435,8 2428,8 0,591 1 methyltransfer 0,013303 0,4038543 106,4 180 0,591 ase like 9 sorting nexin 0,0141792 0,4080251 35,6 60,2 0,591 13 calcium modulating 0,0468034 0,5203286 298,6 504,9 0,591 ligand hypothetical gene supported by 0,0015227 0,2418041 28,4 48,1 0,59 AK093779 MTERF domain 0,0104639 0,3766691 56 94,9 0,59 containing 2 Cbp/p300- interacting transactivator, with Glu/Asp- rich carboxy- terminal 0,0113453 0,3858197 54,5 92,3 0,59 domain, 1 ring finger and CHY zinc finger domain 0,0114713 0,3876349 105,9 179,6 0,59 containing 1

leucine rich repeat 0,0218589 0,4535618 95,7 162,1 0,59 containing 37B oxysterol binding protein- 0,0219047 0,4540657 186,5 316 0,59 like 11

polymerase (RNA) III (DNA directed) polypeptide E 0,0247336 0,4667247 79,9 135,4 0,59 (80kD) Nipped-B homolog 0,0272997 0,4727831 181,1 306,8 0,59 (Drosophila) CDNA FLJ12038 fis, clone HEMBB10019 0,0360233 0,4990053 66,5 112,8 0,59 22 Transcribed 0,0482026 0,5224951 34,1 57,8 0,59 locus

cell division cycle 2, G1 to 131 0,0009134 0,2205071 9,3 15,8 0,589 S and G2 to M FIP1 like 1 (S. 0,0018214 0,2495866 98,6 167,4 0,589 cerevisiae) forkhead box 0,0030183 0,2910986 229,1 388,9 0,589 J3 0,0052499 0,3267775 99,8 169,4 0,589 KIAA1429 cyclin- dependent 0,0175491 0,4320113 36,6 62,1 0,589 kinase 8

far upstream element (FUSE) binding 0,031581 0,4889931 91,4 155,2 0,589 protein 1 heterogeneous nuclear ribonucleoprot 0,0403195 0,509881 89,7 152,3 0,589 ein D-like

chromosome 2 open reading 0,042309 0,5127624 95,3 161,7 0,589 frame 56

growth arrest- 0,0475677 0,521195 125,7 213,3 0,589 specific 2 like 1 G patch domain 0,001466 0,2418041 168,1 285,8 0,588 containing 8

DEAD (Asp- Glu-Ala-Asp) box 0,006586 0,3412079 40,5 68,9 0,588 polypeptide 28 protein phosphatase 1, regulatory (inhibitor) 0,0068818 0,3445627 327,4 556,8 0,588 subunit 11 0,0093044 0,3687888 12,7 21,6 0,588 mitochondrial ribosomal 0,0107051 0,3795799 284,2 483,7 0,588 protein L49 discs, large homolog 1 0,0173417 0,4305249 129,8 220,8 0,588 (Drosophila)

ubiquitin protein ligase E3 component 0,019208 0,4417307 148,1 251,9 0,588 n-recognin 2 ubiquitin specific 0,0205104 0,4485902 497,6 846,1 0,588 peptidase 16 hypothetical protein 0,0253269 0,4702698 34,3 58,3 0,588 BC002926 dispatched homolog 1 0,0266347 0,472096 38,8 66 0,588 (Drosophila) Ribosomal 0,0011912 0,227535 27,1 46,2 0,587 protein L37 Abelson helper integration site 0,0132414 0,4032981 34,3 58,4 0,587 1 suppressor of variegation 4- 20 homolog 1 0,0179379 0,4352115 175 298,1 0,587 (Drosophila)

transmembran 0,0217549 0,4524803 227,1 387 0,587 e protein 203 component of oligomeric golgi complex 0,0246344 0,4667247 109,1 186 0,587 3 hypothetical protein 0,0489424 0,523967 90,5 154,2 0,587 FLJ14803

0,04987 0,5253646 864,3 1472,1 0,587 glycerol kinase telomeric repeat binding factor (NIMA- 0,049923 0,5254168 94,9 161,8 0,587 interacting) 1 YOD1 OTU deubiquinating enzyme 1 homolog (S. 0,0014771 0,2418041 58,2 99,4 0,586 cerevisiae) transmembran 0,0016132 0,2418041 27,5 46,9 0,586 e protein 22 Chromosome 21 open reading frame 0,0022974 0,2707473 18,4 31,4 0,586 45

chromosome 8 open reading 0,0054375 0,3274124 38,5 65,7 0,586 frame 59 translocase of inner mitochondrial membrane 22 homolog 0,0066463 0,3412079 51,2 87,4 0,586 (yeast)

transcription factor 7-like 2 (T-cell specific, 0,0078348 0,3516976 71,2 121,4 0,586 HMG-box) CDNA FLJ36838 fis, clone ASTRO201142 0,0093464 0,3687888 53,3 90,9 0,586 6 FtsJ homolog 0,0152806 0,415674 110,6 188,7 0,586 2 (E. coli)

inositol polyphosphate- 5-phosphatase 0,0166415 0,425997 86,8 148,1 0,586 F transcription factor 7-like 2 (T-cell specific, 0,0191234 0,4415733 92,9 158,5 0,586 HMG-box) DIS3 mitotic control homolog (S. 0,0318874 0,4894884 164,6 281,1 0,586 cerevisiae) regulatory solute carrier protein, family 0,0386038 0,5072367 47,9 81,8 0,586 1, member 1 TSR1, 20S rRNA accumulation, homolog (S. 0,0406534 0,5112983 96,2 164,3 0,586 cerevisiae) Family with sequence similarity 98, 0,0441366 0,5145349 124,8 212,8 0,586 member B

heterogeneous nuclear ribonucleoprot ein U (scaffold attachment 0,0442926 0,5146068 35,9 61,3 0,586 factor A) chromosome 10 open reading frame 195 0,0007875 0,2088164 22,1 37,8 0,585 78 translocation 45 0,0009177 0,2205071 1007,9 1721,8 0,585 protein 1 YLP motif 0,0048423 0,3211399 127,7 218,4 0,585 containing 1 coiled-coil domain 0,0097517 0,3696189 265,4 453,8 0,585 containing 59 0,0138356 0,4051745 1192,8 2039,8 0,585 ATP-binding cassette, sub- family A (ABC1), 0,013843 0,4051745 127,7 218,3 0,585 member 1 zinc finger, DHHC-type 0,0173963 0,4305249 68 116,2 0,585 containing 17 Clone CDABP0105 mRNA 0,0176422 0,433133 90,6 155 0,585 sequence 0,0346797 0,4971024 108 184,5 0,585 calpain 7 ceroid- lipofuscinosis, neuronal 8 (epilepsy, progressive with mental 0,0403003 0,509881 110,2 188,4 0,585 retardation) Smith-Magenis syndrome chromosome region, 0,0075901 0,3505421 859,9 1472,6 0,584 candidate 8 PDZ and LIM 0,0198298 0,4461705 30,1 51,5 0,584 domain 4 cytoskeleton associated 0,0283025 0,4764283 119,2 204,1 0,584 protein 5 bactericidal/per meability- increasing 0,0315251 0,4886216 47,4 81,2 0,584 protein cell division cycle 2-like 1 (PITSLRE proteins) /// cell division cycle 2- like 2 (PITSLRE 0,0360941 0,4991009 88,6 151,8 0,584 proteins)

caspase recruitment domain family, 0,045034 0,516331 104,3 178,6 0,584 member 8 high mobility group nucleosomal binding domain 0,0043958 0,3197234 310,6 532,4 0,583 4

leukocyte immunoglobuli n-like receptor, subfamily B (with TM and ITIM domains), 0,0052883 0,3267775 922 1582,1 0,583 member 1

IK cytokine, down-regulator 0,0070756 0,3458012 449,8 770,9 0,583 of HLA II heterogeneous nuclear ribonucleoprot 0,014227 0,4080969 228,6 392,2 0,583 ein A3 aminoadipate- semialdehyde dehydrogenas e- phosphopantet heinyl 0,0401275 0,5094524 101,1 173,4 0,583 transferase hydroxysteroid (17-beta) dehydrogenas 0,0035563 0,3039332 420,6 722,4 0,582 e 11 zinc finger 0,016017 0,4211937 87,2 149,9 0,582 protein 770 CDNA clone IMAGE:574563 0,0190145 0,4412639 111 190,6 0,582 9 0,0275359 0,473162 87,8 150,9 0,582 KIAA1333 exosome 0,0358479 0,498925 288,9 496,5 0,582 component 8 zinc finger 0,0477375 0,521195 77,8 133,7 0,582 protein 148 RNA binding motif protein 0,0482355 0,5224951 91 156,4 0,582 35B 213 0,0003726 0,1824597 215,6 371,4 0,581 CHK1 checkpoint homolog (S. 0,0035406 0,3039332 14,7 25,3 0,581 pombe) Cell division cycle and apoptosis 0,0077803 0,3510054 17,5 30,1 0,581 regulator 1 zinc finger 0,008375 0,3576553 16,9 29,1 0,581 protein 45 Nipped-B homolog 0,0158558 0,4196703 291,2 501 0,581 (Drosophila) forkhead box 0,0199229 0,4467943 890,9 1532,1 0,581 O3

chromosome 2 open reading 0,0224783 0,4585825 119,1 204,9 0,581 frame 59

chromosome 7 open reading 0,0328934 0,4930759 205,1 352,8 0,581 frame 30 RAD17 homolog (S. 0,0415219 0,5116908 124,5 214,3 0,581 pombe) ring finger 188 0,0009863 0,2205294 138,9 239,6 0,58 protein 113A

splicing factor, arginine/serine- 0,0109504 0,3829822 234,6 404,6 0,58 rich 7, 35kDa enhancer of polycomb homolog 2 0,0121745 0,3928661 101 174,2 0,58 (Drosophila) Programmed 0,020864 0,448736 30,1 51,9 0,58 cell death 5 zinc finger 0,0225015 0,4588846 47,6 82 0,58 protein 182 T-cell acute lymphocytic 0,0322048 0,4912811 23,9 41,2 0,58 leukemia 1 Transcribed 0,0030372 0,2916576 11,7 20,2 0,579 locus Transcribed 0,0055768 0,3279506 31,2 53,9 0,579 locus tetratricopeptid e repeat domain 4 /// chromosome 1 open reading 0,0146907 0,4110614 176,1 304,1 0,579 frame 175 polycomb group ring 0,0167769 0,4260897 53,4 92,3 0,579 finger 6

dihydrouridine synthase 3-like 0,0334773 0,493712 66,8 115,4 0,579 (S. cerevisiae) Transcribed 0,048277 0,5224951 309,3 533,8 0,579 locus microcephalin 27 0,0003062 0,1742973 35,7 61,8 0,578 1

RAP1 interacting factor homolog 253 0,0006196 0,1980347 56,9 98,4 0,578 (yeast)

ring finger and CCCH-type zinc finger 0,0042491 0,3197234 61,8 106,9 0,578 domains 2

coiled-coil domain 0,0051458 0,3258567 43,7 75,6 0,578 containing 128 tripartite motif- 0,009544 0,3688312 140,1 242,5 0,578 containing 27 proteasome (prosome, macropain) 26S subunit, non-ATPase, 0,0163131 0,4235618 63,3 109,5 0,578 11 HECT domain 0,0209188 0,448736 422,3 730,9 0,578 containing 1 ubiquitin specific 0,0268106 0,4727831 90,3 156,1 0,578 peptidase 34 PDZ and LIM domain 7 0,0415234 0,5116908 42,6 73,7 0,578 (enigma) CSE1 chromosome segregation 1- 0,044128 0,5145349 295,4 511,2 0,578 like (yeast) ubiquitin specific 0,0031695 0,2982658 50,3 87,1 0,577 peptidase 34 replication factor C (activator 1) 1, 0,0113593 0,3858197 153,5 265,9 0,577 145kDa mitogen- activated protein kinase 0,0182294 0,436017 50,5 87,5 0,577 kinase 7 pleckstrin homology, Sec7 and coiled-coil 0,0296083 0,4819829 235,9 408,8 0,577 domains 4 ubiquitin specific 129 0,0009406 0,2205071 48,5 84,2 0,576 peptidase 34 zinc finger 0,0025479 0,2764017 9,9 17,2 0,576 protein 684

Smith-Magenis syndrome chromosome region, 0,0119377 0,3901337 53,2 92,4 0,576 candidate 8 dyskeratosis congenita 1, 0,014669 0,410964 257,9 447,9 0,576 dyskerin mediator complex 0,0206662 0,4485902 160,4 278,6 0,576 subunit 6

transmembran e protein 57 /// family with sequence 0,0235114 0,4632294 86,9 150,8 0,576 similarity 122B

coiled-coil domain 0,0252958 0,4702698 15,1 26,2 0,576 containing 142 zinc finger 0,0285838 0,4776731 92,2 160,2 0,576 protein 639 AT hook containing transcription 0,0367927 0,5020317 64,4 111,8 0,576 factor 1 EF-hand calcium binding domain 0,0448878 0,516331 9,1 15,8 0,576 7

RD RNA 0,0050903 0,3253354 558,5 971,4 0,575 binding protein structural maintenance of chromosomes 0,006151 0,3363059 21 36,5 0,575 4 neuroguidin, EIF4E binding 0,0062713 0,3373399 295,2 513,4 0,575 protein Fanconi anemia, complementati 0,0077567 0,3510054 100,7 175 0,575 on group L

zinc finger, CCHC domain 0,0081528 0,3562602 130,9 227,8 0,575 containing 9 neurofibromin 1 (neurofibromat osis, von Recklinghause n disease, Watson 0,008164 0,3562602 50,5 87,8 0,575 disease) CDNA clone IMAGE:526137 0,0102109 0,3757604 18,1 31,5 0,575 5 Transcribed 0,010659 0,3792247 66,8 116,1 0,575 locus mitochondrial ribosomal 0,0116026 0,3891601 156,5 272,2 0,575 protein L38 0,0120684 0,3915963 14,5 25,2 0,575 interleukin 1, 0,013693 0,4046068 192,4 334,5 0,575 alpha hydroxysteroid (17-beta) dehydrogenas e 6 homolog 0,0228823 0,4613163 9,6 16,7 0,575 (mouse) FXYD domain containing ion transport 0,0360721 0,4990491 152,8 265,9 0,575 regulator 6 Hermansky- Pudlak 0,045932 0,5183695 20,4 35,5 0,575 syndrome 3

Clone HLS_IMAGE_ 204740 mRNA 0,046245 0,519094 57,2 99,4 0,575 sequence Fanconi anemia, complementati 0,0026723 0,2842568 20,5 35,7 0,574 on group M DEAD (Asp- Glu-Ala-Asp) box polypeptide 3, 0,0090596 0,3658299 61 106,2 0,574 Y-linked nucleoporin 0,011553 0,3885321 125,2 218,1 0,574 214kDa

transcription factor 7-like 2 (T-cell specific, 0,0125027 0,3964301 146,6 255,5 0,574 HMG-box)

chromosome 8 open reading 0,0136296 0,4046068 553 963,8 0,574 frame 59 GrpE-like 1, mitochondrial 0,0252459 0,4702698 165,3 287,9 0,574 (E. coli) 0,0381568 0,5072367 39,5 68,8 0,574 claudin 7 transducer of 0,039873 0,5087876 105 183 0,574 ERBB2, 1 collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and 0,0460184 0,5183695 101,1 176,2 0,574 recessive) synaptophysin- 0,0480176 0,5221484 358,3 623,8 0,574 like 1

splicing factor, arginine/serine- 50 0,0007238 0,2084556 1391,5 2428,3 0,573 rich 7, 35kDa proteasome (prosome, macropain) activator 0,0019073 0,2536814 49,7 86,8 0,573 subunit 4 mitochondrial ribosomal 0,00322 0,2999829 177,2 309 0,573 protein S18B ankyrin repeat 0,0033054 0,3022119 228,3 398,2 0,573 domain 49

NDC80 homolog, kinetochore complex component (S. 0,0038629 0,3115104 10,2 17,8 0,573 cerevisiae) zinc finger CCCH-type 0,0181519 0,4356695 104 181,6 0,573 containing 13 RAB11 family interacting protein 2 (class 0,0187779 0,4401921 210,3 367,3 0,573 I) cyclin B1 interacting 0,0377057 0,5066501 163,1 284,5 0,573 protein 1 oxysterol binding protein- 0,001667 0,2418041 192,4 336,6 0,572 like 2 CDNA clone IMAGE:574563 0,0039182 0,3127885 58,5 102,3 0,572 9

asp (abnormal spindle) homolog, microcephaly associated 0,0041817 0,3171226 9,9 17,3 0,572 (Drosophila) zinc finger, DHHC-type 0,0087196 0,3604104 493,9 864,1 0,572 containing 6 CDNA FLJ36867 fis, clone ASTRO201649 0,0179063 0,4347367 96,7 169 0,572 1 family with sequence similarity 48, 0,0277445 0,4745266 49,8 87,1 0,572 member A breast carcinoma amplified 0,0287521 0,4791082 184,8 323 0,572 sequence 2 folliculin interacting 0,0348967 0,4971024 76,8 134,2 0,572 protein 1

Smith-Magenis syndrome chromosome region, 0,0375636 0,5058596 163,5 286 0,572 candidate 8 aquarius homolog 0,0413942 0,5116636 48 83,9 0,572 (mouse)

chromosome 6 open reading 189 0,000944 0,2205071 145,4 254,5 0,571 frame 136 Transcribed 0,001573 0,2418041 152,8 267,4 0,571 locus chromosome 20 open reading frame 0,0042738 0,3197234 34,1 59,7 0,571 67 0,0066913 0,3425532 14,4 25,2 0,571 KIAA1429

solute carrier family 39 (zinc transporter), 0,0151504 0,4152121 95,3 167 0,571 member 7 centromere 0,0156747 0,4190779 34,2 59,9 0,571 protein L THAP domain 0,0170722 0,427783 64,3 112,6 0,571 containing 7 tRNA methyltransfer ase 12 homolog (S. 0,020575 0,4485902 50,8 88,9 0,571 cerevisiae) mediator complex 0,0232089 0,4625449 180,4 316,2 0,571 subunit 31 REST 21 0,0005035 0,1940962 38,2 67 0,57 corepressor 3 suppressor of cytokine 0,0010687 0,2213302 90,4 158,7 0,57 signaling 4 Transcribed 0,0032335 0,2999829 26,9 47,2 0,57 locus allograft inflammatory 0,0039339 0,3127885 648,4 1137,9 0,57 factor 1 zinc finger 0,0158996 0,4199568 119,8 210,1 0,57 protein 638 tripartite motif- 0,019131 0,4415733 424,2 744 0,57 containing 38 angel homolog 0,0347703 0,4971024 47,6 83,5 0,57 2 (Drosophila)

excision repair cross- complementing rodent repair deficiency, complementati 0,0353705 0,4983242 17,1 30 0,57 on group 4

signal recognition 0,0435408 0,5138341 144 252,5 0,57 particle 72kDa Transcribed 190 0,0009178 0,2205071 157,7 277,1 0,569 locus muskelin 1, intracellular mediator containing 0,0010973 0,2213833 95,5 167,8 0,569 kelch motifs speckle-type POZ protein- 0,0072684 0,3476813 151,8 266,8 0,569 like NMDA receptor 0,0197925 0,4458817 45,2 79,4 0,569 regulated 2 TAF15 RNA polymerase II, TATA box binding protein (TBP)- associated 0,046191 0,5189014 104,8 184,2 0,569 factor, 68kDa pinin, desmosome associated 0,0037122 0,3106276 390,8 688,1 0,568 protein ubiquitin associated 0,0059908 0,3318612 206,6 363,5 0,568 protein 2 discs, large homolog 1 0,0112987 0,3858197 33,2 58,4 0,568 (Drosophila) pyrophosphata se (inorganic) 0,0261894 0,4705663 44,8 78,9 0,568 2

COP9 constitutive photomorphog enic homolog subunit 2 0,0265364 0,472096 37,4 65,9 0,568 (Arabidopsis) 0,0270329 0,4727831 64,6 113,8 0,568 CDNA FLJ33153 fis, clone UTERU200033 0,0310149 0,4871817 40,8 71,8 0,568 2 DEAD (Asp- Glu-Ala-Asp) box 0,033021 0,4934061 33,2 58,5 0,568 polypeptide 55

Homo sapiens, clone IMAGE:46702 0,0386736 0,5072367 15,5 27,3 0,568 53, mRNA mitochondrial ribosomal 0,0439122 0,5143739 304,5 535,9 0,568 protein S22

jumonji domain 0,0037838 0,3114214 80 141 0,567 containing 1B

transmembran e and coiled- 0,005673 0,3299401 28,1 49,6 0,567 coil domains 6

ring finger and CCCH-type zinc finger 0,0096807 0,3696189 45,9 81 0,567 domains 2 La ribonucleoprot ein domain family, member 0,0106606 0,3792247 244,1 430,3 0,567 7 similar to FLJ16518 0,0137 0,4046068 27,6 48,7 0,567 protein ubiquitin specific 0,0219081 0,4540657 124,2 219,2 0,567 peptidase 10 tetratricopeptid e repeat 0,0239421 0,4638862 174,5 307,9 0,567 domain 32 KIAA1466 0,0415322 0,5116908 264,4 466,6 0,567 gene WD repeat 0,0020887 0,2600279 85,1 150,3 0,566 domain 3 leucyl-tRNA 0,0027277 0,2846641 66,7 117,8 0,566 synthetase CDNA FLJ41972 fis, clone SKNMC20039 0,0100955 0,3747632 28,2 49,8 0,566 87 0,0132273 0,4032981 79,8 141 0,566 CD44 molecule (Indian blood 0,0238479 0,4633196 142,1 251 0,566 group) Transcribed locus, weakly similar to NP_001909.1 dihydrolipoami de branched chain transacylase [Homo 0,0271424 0,4727831 433,6 766,7 0,566 sapiens] 0,0413578 0,5116636 254,8 450,4 0,566 syntaxin 16

PRP38 pre- mRNA processing factor 38 (yeast) domain 175 0,0010053 0,2205294 113 199,9 0,565 containing A tetratricopeptid e repeat 0,0011099 0,2231021 131,5 232,9 0,565 domain 31 neurofibromin 1 (neurofibromat osis, von Recklinghause n disease, Watson 0,0037872 0,3114214 41,1 72,7 0,565 disease) ribonuclease P/MRP 21kDa 0,0110117 0,3829822 108,5 191,9 0,565 subunit

ribosomal protein S6 kinase, 90kDa, 0,0240025 0,4640012 81,1 143,6 0,565 polypeptide 5 FtsJ homolog 0,029892 0,4826515 172,9 306,1 0,565 1 (E. coli)

Leukocyte immunoglobuli n-like receptor, subfamily B (with TM and ITIM domains), 0,0344696 0,4962541 1000,7 1771,4 0,565 member 1

TAF5 RNA polymerase II, TATA box binding protein (TBP)- associated 0,037661 0,5065474 32,7 57,9 0,565 factor, 100kDa

DEAD (Asp- Glu-Ala-Asp) box 0,0498131 0,5252551 92,5 163,7 0,565 polypeptide 18 Transcribed 94 0,0005651 0,1943198 28,3 50,2 0,564 locus excision repair cross- complementing rodent repair deficiency, complementati on group 5 (xeroderma pigmentosum, complementati on group G (Cockayne 0,0010826 0,2213833 166,2 294,5 0,564 syndrome))

trafficking protein, kinesin 0,0037608 0,3114214 244,7 433,7 0,564 binding 1

CDNA FLJ31794 fis, clone 0,0038747 0,3120018 39,8 70,6 0,564 NT2RI2008808 Serine 0,0049353 0,3216637 32,5 57,6 0,564 racemase Transcribed 0,0079339 0,3545654 34,2 60,6 0,564 locus

chromosome 9 open reading 0,0104187 0,3766691 254,3 450,6 0,564 frame 80

Full-length cDNA clone CS0DK012YA1 5 of HeLa cells Cot 25- normalized of Homo sapiens 0,0370359 0,5029652 35,4 62,8 0,564 (human) v-raf murine sarcoma viral oncogene 0,0015745 0,2418041 38,3 68 0,563 homolog B1 nucleolar protein 1, 0,0093072 0,3687888 119,6 212,6 0,563 120kDa

ARP5 actin- related protein 5 homolog 0,0093332 0,3687888 73,3 130,3 0,563 (yeast) 0,0105064 0,3766803 28,9 51,3 0,563 glypican 3 aurora kinase 0,0142412 0,4080969 39,6 70,3 0,563 A transketolase (Wernicke- Korsakoff 0,0176818 0,4331491 752,7 1337 0,563 syndrome) 0,0180043 0,4353512 40,6 72,1 0,563 exportin 4 nuclear receptor subfamily 2, group C, 0,0185752 0,4382676 116,8 207,3 0,563 member 2 POT1 protection of telomeres 1 homolog (S. 0,0322828 0,4914731 66,7 118,4 0,563 pombe) nucleoporin 0,0078938 0,3537652 458,9 816,1 0,562 107kDa

zinc finger and BTB domain 0,011491 0,3880608 34,2 60,9 0,562 containing 26 POT1 protection of telomeres 1 homolog (S. 0,0242145 0,4652389 101,1 179,9 0,562 pombe) zinc finger 0,0301366 0,4831575 32,4 57,6 0,562 protein 226 eukaryotic translation elongation factor 1 alpha 0,0306316 0,4860078 151,3 269,3 0,562 1

cyclin- dependent kinase inhibitor 0,0333785 0,493712 318,8 566,8 0,562 1B (p27, Kip1) minichromoso me maintenance complex 0,0456325 0,5175186 74,4 132,4 0,562 component 7

MRNA; cDNA DKFZp564F21 2 (from clone DKFZp564F21 0,0035463 0,3039332 92,2 164,3 0,561 2) hypothetical protein DKFZp564O05 0,0040653 0,3157248 31,3 55,8 0,561 23

DIS3 mitotic control homolog (S. 0,0117714 0,3891601 98,4 175,3 0,561 cerevisiae)-like KIAA1604 0,0118447 0,3891601 94,3 168,1 0,561 protein CD44 molecule (Indian blood 0,0251147 0,4697677 400,8 714,1 0,561 group)

chromosome 3 open reading 0,0320824 0,4906561 31,1 55,4 0,561 frame 62 discs, large homolog 1 0,0328446 0,493025 57,4 102,3 0,561 (Drosophila) 0,0362868 0,5001557 61,7 109,9 0,561 KIAA0907 purinergic receptor P2Y, G-protein 0,0366144 0,5012039 12,5 22,3 0,561 coupled, 10 structural maintenance of chromosomes 0,0018362 0,2504655 50,6 90,3 0,56 2

splicing factor, arginine/serine- rich 8 (suppressor-of- white-apricot homolog, 0,0034575 0,3039332 120,5 215,3 0,56 Drosophila) zinc finger, MYND-type 0,0058924 0,3307111 89,3 159,4 0,56 containing 8

chromosome 1 open reading 0,0073692 0,3497491 171,7 306,8 0,56 frame 164 Transcribed locus, moderately similar to XP_517655.1 PREDICTED: similar to KIAA0825 protein [Pan 0,0112216 0,3858197 33,3 59,5 0,56 troglodytes] mitochondrial ribosomal 0,0221051 0,4559722 244,3 436,5 0,56 protein L22

2'-5'- oligoadenylate 0,0414567 0,5116908 1608,3 2872,5 0,56 synthetase-like

hexamethylene bis-acetamide 0,0043012 0,3197234 97 173,6 0,559 inducible 1 Rab geranylgeranyl transferase, 0,0059519 0,331305 1181,6 2113,8 0,559 beta subunit RNA binding motif protein 0,0119833 0,3910796 135,3 242,1 0,559 28 coiled-coil domain 0,0137126 0,4046068 77,7 139 0,559 containing 45 polymerase (RNA) II (DNA directed) 0,0255477 0,4702698 66,7 119,3 0,559 polypeptide D Transcribed 0,0289558 0,480197 30,5 54,6 0,559 locus Transcribed 0,0443994 0,5146943 113,5 203,1 0,559 locus

small nucleolar RNA host gene (non-protein 0,0010514 0,2205294 1741,5 3118,7 0,558 coding) 6 0,0017424 0,2455456 52,1 93,4 0,558 KIAA1333 ring finger 0,0021156 0,260519 42 75,3 0,558 protein 41 trinucleotide repeat 0,0059156 0,3307111 181,9 326,2 0,558 containing 6A tripartite motif- 0,0061462 0,3363059 105,8 189,5 0,558 containing 8 CDNA FLJ40566 fis, clone THYMU20047 0,0076869 0,3505421 49,3 88,3 0,558 33 zinc finger 0,0152018 0,4155792 173,4 310,8 0,558 protein 146

FK506 binding protein 11, 19 0,02592 0,4702698 141,3 253,2 0,558 kDa ribonuclease P/MRP 40kDa 0,047359 0,521195 23,2 41,6 0,558 subunit mitochondrial ribosomal 0,0089284 0,3635583 272,7 489,4 0,557 protein L16 mitochondrial ribosomal 0,0093539 0,3687888 305,9 548,8 0,557 protein S5 nucleolar protein family A, member 1 (H/ACA small nucleolar 0,0132828 0,4038543 129,8 233 0,557 RNPs) Transcribed 0,0167074 0,4260897 60,5 108,7 0,557 locus 0,0179513 0,4352115 509,6 914,8 0,557 fibrillarin adenylate 0,0207754 0,448736 117,6 211,2 0,557 kinase 1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, 0,0217387 0,4524803 16,1 28,9 0,557 member 2

TRM1 tRNA methyltransfer ase 1 homolog 0,0290989 0,4811681 102,4 183,7 0,557 (S. cerevisiae) Morf4 family associated 0,0379492 0,5071739 113,7 204,2 0,557 protein 1-like 1 pinin, desmosome associated 0,0019 0,2536814 137,5 247,1 0,556 protein CCR4-NOT transcription complex, 0,0020601 0,2589333 449,1 807,1 0,556 subunit 2 tripartite motif- 0,0026974 0,2846641 479,7 862,2 0,556 containing 38 zinc finger 0,0095109 0,3688312 32,2 57,9 0,556 protein 227

jumonji domain 0,0143947 0,4088469 162,8 292,9 0,556 containing 1A

splicing factor, arginine/serine- rich 1 (splicing factor 2, alternate 0,0162887 0,4235618 56,9 102,4 0,556 splicing factor) oxidase (cytochrome c) assembly 1- 0,0238742 0,4633731 843,9 1517,1 0,556 like CDNA FLJ42968 fis, clone BRSTN201695 0,0244385 0,4660137 27,9 50,2 0,556 4 Itchy homolog E3 ubiquitin protein ligase 0,0279125 0,4749816 61 109,7 0,556 (mouse) ceroid- lipofuscinosis, neuronal 8 (epilepsy, progressive with mental 0,0308419 0,4870313 187,8 337,5 0,556 retardation)

chromosome 6 open reading 0,0010267 0,2205294 654,1 1177,6 0,555 frame 48 zinc finger 0,0021669 0,2638647 148,8 268,3 0,555 protein 294 fragile X mental retardation, autosomal 0,0034312 0,3039332 307,3 553,7 0,555 homolog 1 SH3 domain containing ring 0,0047191 0,3197234 13,6 24,5 0,555 finger 1 Transcribed 0,0064408 0,3395481 189,3 340,8 0,555 locus Kruppel-like 0,0075053 0,3505421 2396,9 4316,4 0,555 factor 4 (gut) hypothetical protein 0,0240684 0,4645353 19,7 35,5 0,555 LOC283551 NOL1/NOP2/S un domain family, member 0,0254636 0,4702698 223,9 403,2 0,555 3

proteasome (prosome, macropain) 26S subunit, 0,0270689 0,4727831 932,9 1681,8 0,555 non-ATPase, 6 Rab acceptor 1 0,001848 0,2504655 613,7 1108,1 0,554 (prenylated) chromosome 11 open reading frame 0,0023564 0,2714688 40,3 72,8 0,554 30

chromosome 1 open reading 0,0205941 0,4485902 67,2 121,3 0,554 frame 142

arachidonate 5- lipoxygenase- activating 0,0205955 0,4485902 927,1 1672,8 0,554 protein RAD23 homolog B (S. 0,0206924 0,4485902 283,7 511,7 0,554 cerevisiae) CDNA: FLJ23572 fis, clone 0,0215613 0,4524803 88,2 159,2 0,554 LNG12403 0,021646 0,4524803 82,1 148,1 0,554 splicing factor, arginine/serine- 0,0270789 0,4727831 309,2 558,1 0,554 rich 18 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 0,0010395 0,2205294 80,7 146 0,553 (yeast) Transcribed 0,0016431 0,2418041 32,6 58,9 0,553 locus nucleolar 0,0017832 0,2490398 216 390,3 0,553 protein 11

ankyrin repeat and SOCS box- 0,0019116 0,2536814 44,6 80,7 0,553 containing 2 Phosphonofor mate immuno- associated 0,0054703 0,3279481 73,3 132,5 0,553 protein 5 centromere 0,0082364 0,3566213 29,8 53,9 0,553 protein L FtsJ homolog 0,0119028 0,389692 185,8 335,7 0,553 3 (E. coli) serine/threonin e kinase 11 interacting 0,0124965 0,3964301 97 175,5 0,553 protein zinc finger 0,0143419 0,4083537 89,8 162,4 0,553 protein 692 PRP6 pre- mRNA processing factor 6 homolog (S. 0,0150551 0,4143327 71,7 129,6 0,553 cerevisiae) diacylglycerol kinase, alpha 0,0319212 0,4894884 26,7 48,3 0,553 80kDa spastic ataxia of Charlevoix- Saguenay 0,044516 0,5147869 18,2 32,9 0,553 (sacsin) ribosomal 0,0039273 0,3127885 4365,2 7910,9 0,552 protein S6 CDNA FLJ37855 fis, clone BRSSN201463 0,004747 0,3199091 13,8 25 0,552 6

chromosome 3 open reading 0,0048709 0,3211399 169,4 306,9 0,552 frame 58 Transcribed 0,0091672 0,3683909 20,3 36,8 0,552 locus family with sequence similarity 62 (C2 domain containing) 0,0183385 0,4368809 62,4 113,1 0,552 member B

Neutral sphingomyelin ase (N-SMase) activation associated 0,019297 0,4417307 94,5 171,2 0,552 factor TATA box binding protein (TBP)- associated factor, RNA polymerase I, 0,0259525 0,4702698 38,9 70,5 0,552 A, 48kDa

DEAH (Asp- Glu-Ala-His) box 0,0454816 0,5172371 183,3 331,9 0,552 polypeptide 40 UPF3 regulator of nonsense transcripts homolog B 246 0,000922 0,2205071 192,4 349 0,551 (yeast)

Transcribed locus, strongly similar to NP_005077.2 sarcospan [Homo 0,0116183 0,3891601 11,9 21,6 0,551 sapiens] zinc finger 0,0120393 0,3915788 562,8 1020,7 0,551 protein 697 Transcribed 0,0141144 0,4075754 220,1 399,4 0,551 locus Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 0,017477 0,4308183 50,6 91,8 0,551 1

0,0261011 0,4702698 885,1 1606,6 0,551 glycerol kinase chromosome 11 open reading frame 0,0494998 0,5248641 232,5 421,6 0,551 48 0,0020566 0,2589333 11,6 21,1 0,55 CCAAT/enhan cer binding protein 0,0023256 0,2709605 5503,5 10009,5 0,55 (C/EBP), beta zinc ribbon domain 0,0023507 0,2714688 100,2 182,2 0,55 containing 1

human immunodeficie ncy virus type I enhancer binding protein 0,0027694 0,2846759 275,8 501,7 0,55 1 gap junction protein, alpha 0,0039202 0,3127885 13,2 24 0,55 1, 43kDa zinc finger 0,0046268 0,3197234 61,6 112,1 0,55 protein 558 Fc fragment of IgA, receptor 0,0058222 0,3305595 12,6 22,9 0,55 for Transcribed locus, strongly similar to XP_001174013 .1 PREDICTED: cortactin isoform 1 [Pan 0,0093272 0,3687888 56,6 103 0,55 troglodytes] Transcribed locus, moderately similar to NP_060312.1 hypothetical protein LOC55652 [Homo 0,0127927 0,4003342 51,5 93,7 0,55 sapiens]

Abelson helper integration site 0,0140455 0,4070665 54,1 98,3 0,55 1 zinc finger, MYND-type 0,0146482 0,4109237 120,3 218,7 0,55 containing 8 0,0146797 0,410964 65,6 119,3 0,55 spastin G protein- coupled 0,0164526 0,4241141 31,3 56,9 0,55 receptor 177 mitochondrial ribosomal 0,0185888 0,4382676 415,2 754,4 0,55 protein S18C integrator complex 0,027065 0,4727831 42,9 78 0,55 subunit 2

polymerase (RNA) III (DNA directed) polypeptide E 0,0323708 0,4917015 12,1 22 0,55 (80kD) hypothetical protein 204 0,0005869 0,1949966 126 229,6 0,549 BC007882 regulatory factor X- associated 202 0,0006949 0,2064873 17,9 32,6 0,549 protein protein associated with topoisomerase II homolog 1 130 0,0009314 0,2205071 635,2 1156,7 0,549 (yeast) ribosomal protein L36a /// similar to large subunit ribosomal 0,001021 0,2205294 4447,4 8095,5 0,549 protein L36a Transcribed 0,0025056 0,2756013 127,8 232,6 0,549 locus

LTV1 homolog 0,0028875 0,288618 167 304,3 0,549 (S. cerevisiae)

polymerase (RNA) III (DNA directed) 0,0046953 0,3197234 51,6 94 0,549 polypeptide B RAN binding 0,004763 0,3199091 88,7 161,7 0,549 protein 6 phosphoinositi de-3-kinase, class 2, alpha 0,0048659 0,3211399 79,6 145,1 0,549 polypeptide mitochondrial ribosomal 0,0056543 0,329232 142,4 259,3 0,549 protein S31 0,0077843 0,3510054 724,4 1318,5 0,549 methyltransfer 0,0196247 0,4448509 237 431,5 0,549 ase like 5 Wolf- Hirschhorn syndrome 0,0017234 0,2447452 46,1 84,2 0,548 candidate 2 Sp1 transcription 0,0032597 0,3005465 62,7 114,4 0,548 factor CDNA FLJ10417 fis, clone NT2RP100011 0,0097537 0,3696189 41,6 75,9 0,548 2

neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, 0,0482807 0,5224951 3651,6 6663,2 0,548 autosomal 2) 0,0027834 0,2846759 84,8 155 0,547 homeobox B2 S100 calcium binding protein 0,0056419 0,3288602 507,8 928,2 0,547 A10

superkiller viralicidic activity 2-like 2 0,0117956 0,3891601 281,1 514 0,547 (S. cerevisiae) DTW domain 0,0157544 0,4193631 24,5 44,8 0,547 containing 1

cyclin- dependent kinase inhibitor 2C (p18, 0,0295646 0,4819829 20,4 37,3 0,547 inhibits CDK4) timeless homolog 0,031419 0,488547 75,3 137,6 0,547 (Drosophila) hect domain and RLD 2 pseudogene 3 /// hect domain and RLD 2 pseudogene 2 /// hect domain and RLD 2 0,005477 0,3279506 110,1 201,6 0,546 pseudogene

methyltransfer ase 10 domain 0,0058658 0,3307111 180,3 330 0,546 containing abhydrolase domain 0,0180705 0,4355503 89,8 164,4 0,546 containing 13 0,0013752 0,238971 681,1 1249,5 0,545 importin 7 0,0034289 0,3039332 27,1 49,7 0,545 centaurin, 0,0045958 0,3197234 63,8 117 0,545 delta 3 Transcribed 0,0066104 0,3412079 23,6 43,3 0,545 locus C2 calcium- dependent domain 0,0094658 0,3688312 104,8 192,2 0,545 containing 3 ribonuclease 0,011846 0,3891601 93,2 171 0,545 H2, subunit A transmembran 0,0134589 0,4041641 163,9 300,6 0,545 e protein 48 phosphoinositi de-3-kinase, class 2, alpha 0,0142412 0,4080969 179,3 328,8 0,545 polypeptide dyskeratosis congenita 1, 0,0158734 0,4196703 158,4 290,7 0,545 dyskerin AF4/FMR2 family, member 0,0249083 0,468375 56,1 103 0,545 4 FCF1 small subunit (SSU) processome component homolog (S. 0,0274387 0,4727831 26,2 48,1 0,545 cerevisiae) translocation 0,0310001 0,4871817 67,1 123,1 0,545 protein 1

Full-length cDNA clone CS0DI039YF1 2 of Placenta Cot 25- normalized of Homo sapiens 0,0315343 0,4886216 9,1 16,7 0,545 (human) Huntingtin interacting 0,0045519 0,3197234 41 75,3 0,544 protein 1 protein prenyltransfera se alpha subunit repeat 0,0064241 0,3395481 162,9 299,3 0,544 containing 1

ORM1-like 1 0,0090671 0,3658625 92,3 169,6 0,544 (S. cerevisiae)

caspase recruitment domain family, 0,0135243 0,4041641 127,6 234,5 0,544 member 8 YLP motif 0,0212391 0,4513673 62,2 114,3 0,544 containing 1 ERGIC and 0,0024188 0,2726761 27,1 49,9 0,543 golgi 2 transforming growth factor beta regulator 0,0076917 0,3505421 154 283,8 0,543 1

suppressor of Ty 7 (S. 0,0081482 0,3562602 234 430,9 0,543 cerevisiae)-like Transcribed 0,0089534 0,3635583 26,3 48,4 0,543 locus phosphoinositi de-3-kinase, class 2, alpha 0,0092411 0,3687888 162,7 299,7 0,543 polypeptide NAD(P)H dehydrogenas 0,0094763 0,3688312 618,2 1138,1 0,543 e, quinone 2 CWF19-like 2, cell cycle control (S. 0,0126565 0,3983847 44,1 81,2 0,543 pombe)

chromosome Y open reading 0,0260724 0,4702698 40,8 75,1 0,543 frame 15B tripartite motif- 0,0023771 0,2714688 517,3 955 0,542 containing 38 poly(A) polymerase 0,002617 0,2797591 83,5 154,2 0,542 alpha ubiquitin specific 0,0048879 0,3215956 111,3 205,3 0,542 peptidase 16 major histocompatibili ty complex, 0,007195 0,346291 56 103,4 0,542 class I-related myeloid/lymph oid or mixed- lineage 0,0205506 0,4485902 184,7 341 0,542 leukemia 3 heterogeneous nuclear ribonucleoprot 0,0223579 0,4580941 60,2 111,1 0,542 ein H1 (H) nucleolar protein 5A (56kDa with 0,0405401 0,5108389 226,2 417,1 0,542 KKE/D repeat) 0,0417525 0,5121871 65,2 120,2 0,542 ubiquitin specific 98 0,0004902 0,1940962 692,5 1279,1 0,541 peptidase 3

round spermatid 0,0010537 0,2205294 83,6 154,6 0,541 basic protein 1 Hypothetical gene supported by 0,0013751 0,238971 225,1 415,8 0,541 AK091718 tripartite motif- 0,0279528 0,4753393 61,1 113 0,541 containing 73 6- phosphofructo- 2- kinase/fructose- 2,6- biphosphatase 0,0450884 0,516331 154,9 286,5 0,541 4 basic helix- loop-helix domain containing, 0,0496725 0,5250037 670,5 1240,2 0,541 class B, 2 Hypothetical 176 0,0008263 0,2141135 81,3 150,5 0,54 LOC644617 ubiquitin specific 0,0025395 0,2760381 220,5 408,1 0,54 peptidase 38 pantothenate 0,0051872 0,3263638 119 220,4 0,54 kinase 4

sperm specific 0,0056863 0,3299401 12,9 23,9 0,54 antigen 2

zinc finger and SCAN domain 0,0312939 0,4885021 43,7 80,9 0,54 containing 5 ATPase, class I, type 8B, 0,0366269 0,5012039 22,9 42,4 0,54 member 2 tissue factor pathway inhibitor (lipoprotein- associated coagulation 0,0485643 0,5229602 457 846,3 0,54 inhibitor) Clone 24438 mRNA 0,0023083 0,270829 13,8 25,6 0,539 sequence chromosome 15 open reading frame 0,0111955 0,3858197 611,3 1134 0,539 15 squamous cell carcinoma antigen recognized by 0,0133976 0,4041641 151,2 280,7 0,539 T cells 3 PC4 and SFRS1 interacting 0,0145767 0,4106872 57,5 106,7 0,539 protein 1

transducin-like enhancer of split 4 (E(sp1) homolog, 0,0200437 0,4476045 48 89,1 0,539 Drosophila)

0,0384843 0,5072367 64,8 120,2 0,539 nucleobindin 2

chromosome 4 open reading 0,0400258 0,5087876 114,6 212,5 0,539 frame 14 43 0,0009384 0,2205071 172 319,6 0,538 Importin 7 TIA1 cytotoxic granule- associated RNA binding 0,0013745 0,238971 545,6 1014,1 0,538 protein-like 1 CDNA FLJ39366 fis, clone PEBLM200628 0,0026249 0,2797591 38,2 71 0,538 3 FAST kinase 0,0048435 0,3211399 212,7 395,6 0,538 domains 2 guanine nucleotide binding protein- like 2 0,0112182 0,3858197 184,5 343 0,538 (nucleolar) purine-rich element binding protein 0,0117171 0,3891601 139,9 260,1 0,538 A solute carrier family 36 (proton/amino acid symporter), 0,0155518 0,4179451 402 747,7 0,538 member 4 La ribonucleoprot ein domain family, member 0,0227889 0,460963 64,3 119,6 0,538 2 KIAA1627 93 0,0005859 0,1949966 110,4 205,7 0,537 protein methyltransfer ase 11 domain containing 1 /// similar to methyltransfer ase 11 domain containing 1 0,0030188 0,2910986 275 512,1 0,537 isoform 2 nucleoporin 0,0086185 0,3602917 27,4 51 0,537 like 1

chromosome 6 open reading 0,0114085 0,3864682 123,7 230,3 0,537 frame 130 Transcribed 0,0138041 0,4051745 152,1 283,4 0,537 locus cyclin- dependent 0,0220195 0,4549948 51,3 95,6 0,537 kinase 8 Rap guanine nucleotide exchange 0,0373421 0,5046289 68,9 128,3 0,537 factor (GEF) 6

GC-rich promoter binding protein 0,0040832 0,3162167 112,2 209,3 0,536 1-like 1 multiple endocrine 0,010195 0,3757604 71,7 133,8 0,536 neoplasia I nuclear fragile X mental retardation protein interacting 0,0124094 0,3958483 32,9 61,4 0,536 protein 1 lectin, galactoside- binding, soluble, 8 0,0164072 0,4236538 208,1 388,4 0,536 (galectin 8)

Transcribed locus, strongly similar to XP_517193.1 PREDICTED: similar to Heterogeneou s nuclear ribonucleoprot ein D0 (hnRNP D0) (AU-rich element RNA- binding protein 1) [Pan 0,018377 0,4370198 15,5 28,9 0,536 troglodytes] Transcribed 0,0195978 0,4445887 184,9 344,9 0,536 locus

coiled-coil domain 0,0283907 0,4768853 93,1 173,8 0,536 containing 126 0,0010812 0,2213833 53,4 99,8 0,535 hypothetical 0,0010936 0,2213833 152,3 284,5 0,535 LOC440731

methyltransfer ase 11 domain containing 1 /// similar to methyltransfer ase 11 domain containing 1 0,0047135 0,3197234 122,3 228,4 0,535 isoform 2 myb-like, SWIRM and MPN domains 0,0051396 0,3258567 180,8 338,2 0,535 1 CCR4-NOT transcription complex, 0,0087341 0,3604104 177,5 331,7 0,535 subunit 8 thyroid adenoma 0,0144197 0,4089197 24,4 45,6 0,535 associated zinc finger 0,0183097 0,4366489 71,2 133,2 0,535 protein 689 hypothetical protein 0,0261129 0,4702698 287,9 538 0,535 FLJ10213 synaptotagmin- 0,0292668 0,4812171 155,6 291,1 0,535 like 1 zinc finger 0,0416088 0,511833 177,3 331,7 0,535 protein 791 ribosomal L1 domain 33 0,000147 0,1541482 418 782,3 0,534 containing 1 synaptotagmin binding, cytoplasmic RNA interacting 65 0,0002751 0,1728861 315,7 591,7 0,534 protein

chromosome 15 open reading frame 15 /// similar to ribosomal 0,0035732 0,3039862 607,1 1135,9 0,534 protein L24-like

UTP14, U3 small nucleolar ribonucleoprot ein, homolog A 0,0070197 0,3458012 86,8 162,4 0,534 (yeast) Homo sapiens, clone IMAGE:39069 0,013964 0,4062323 98,4 184,3 0,534 92, mRNA

LTV1 homolog 0,0146408 0,4109237 19,7 36,9 0,534 (S. cerevisiae) 0,0257775 0,4702698 137,2 257 0,534 matrin 3 kelch-like 7 0,0446045 0,5152544 112,5 210,8 0,534 (Drosophila) phosphonofor mate immuno- associated 107 0,0002399 0,16423 631,7 1185,3 0,533 protein 5 HECT domain 0,0010196 0,2205294 33,2 62,3 0,533 containing 1 Protein geranylgeranyl transferase type I, beta 0,0051249 0,3258567 86,9 163,1 0,533 subunit hypothetical protein 0,0062073 0,3366906 20,8 39 0,533 LOC284513 0,0083594 0,3576553 81,8 153,4 0,533 KIAA0495 RNA binding motif protein 0,0094846 0,3688312 169,1 317,2 0,533 27 polymerase (RNA) I polypeptide D, 0,001955 0,2561092 416 782,5 0,532 16kDa H2A histone family, member 0,0034676 0,3039332 2436,6 4577,2 0,532 Z C2 calcium- dependent domain 0,0109093 0,38235 85,1 160 0,532 containing 3 Zinc finger 0,0110705 0,3843913 22,4 42,1 0,532 protein 333

CTD (carboxy- terminal domain, RNA polymerase II, polypeptide A) small 0,0162049 0,423115 223 418,8 0,532 phosphatase 2

transmembran e 4 L six family 0,0492186 0,5246689 31,6 59,4 0,532 member 1 NLR family, pyrin domain 0,0017999 0,2490398 19 35,8 0,531 containing 1 ankyrin repeat and KH domain containing 1 /// ANKHD1- 0,0018534 0,2504655 264,5 497,8 0,531 EIF4EBP3 sema domain, transmembran e domain (TM), and cytoplasmic domain, (semaphorin) 0,0045998 0,3197234 33,9 63,8 0,531 6B oxysterol binding protein- 0,0054395 0,3274124 67,7 127,6 0,531 like 8 CDNA: FLJ23261 fis, clone 0,0101209 0,3751595 70,3 132,4 0,531 COL05862 BTB and CNC homology 1, basic leucine zipper transcription 0,0281652 0,4761728 494,1 930,1 0,531 factor 1 zinc finger, AN1-type 0,0303096 0,4842483 490 923,2 0,531 domain 2A Golgi SNAP receptor complex 0,0307754 0,4866502 15,2 28,6 0,531 member 2 zinc finger, FYVE domain 0,041437 0,5116908 265,5 499,6 0,531 containing 16 additional sex combs like 1 48 0,0007892 0,2088164 105,7 199,6 0,53 (Drosophila) phosphoinositi de-3-kinase, class 2, alpha 0,003075 0,2932482 25,4 47,9 0,53 polypeptide

Transcribed locus, strongly similar to XP_001111447 .1 PREDICTED: transforming growth factor, beta-induced, 68kDa isoform 6 [Macaca 0,0041175 0,3163535 47 88,7 0,53 mulatta] Transcribed 0,0065539 0,3412079 62,3 117,5 0,53 locus Fas (TNFRSF6) associated 0,0135723 0,4041641 23,9 45,1 0,53 factor 1 lipoic acid 0,0278639 0,4745266 31,8 60 0,53 synthetase CDNA clone IMAGE:472373 0,0333374 0,493712 32,3 61 0,53 8 SP100 nuclear 0,0475884 0,521195 39,2 74 0,53 antigen ankyrin repeat and KH domain 96 0,0004991 0,1940962 194,2 367,1 0,529 containing 1 coiled-coil domain 0,005974 0,331305 55,9 105,7 0,529 containing 99 Hypothetical gene supported by 0,0082986 0,3568017 86,2 163 0,529 AK091718

chromosome 6 open reading 0,0114206 0,3866386 45,8 86,5 0,529 frame 203 SFRS12- interacting 0,0246812 0,4667247 31,9 60,3 0,529 protein 1 TATA element modulatory 0,0075341 0,3505421 32,1 60,8 0,528 factor 1

Transcribed locus, strongly similar to NP_00101751 0.1 hypothetical protein LOC498750 [Rattus 0,0177571 0,4331491 3633,5 6883,9 0,528 norvegicus] transforming, acidic coiled- coil containing 0,0208347 0,448736 53,6 101,6 0,528 protein 3 zinc finger CCCH-type, 0,0227375 0,4609465 4727,6 8960,9 0,528 antiviral 1 glioma tumor suppressor candidate 0,0266144 0,472096 2966,3 5612,7 0,528 region gene 2 cytochrome b- 245, beta polypeptide (chronic granulomatous 0,027298 0,4727831 640,8 1213,4 0,528 disease) ankyrin repeat 0,0274427 0,4727831 199,8 378,1 0,528 domain 10 membrane- associated ring finger (C3HC4) 0,0033739 0,3039332 25,8 49 0,527 6 CDNA clone IMAGE:479867 0,0046838 0,3197234 39,4 74,7 0,527 5 ADP- ribosylation factor-like 6 interacting 0,0051553 0,3258567 154,7 293,6 0,527 protein 2

SLU7 splicing factor homolog 0,007985 0,3545654 159,5 302,7 0,527 (S. cerevisiae) exosome 0,02705 0,4727831 55 104,4 0,527 component 3

chromosome 6 open reading 0,0274093 0,4727831 111,6 211,6 0,527 frame 66

angel homolog 0,0347945 0,4971024 101,5 192,6 0,527 2 (Drosophila) Slingshot homolog 1 0,0458564 0,5180163 57,6 109,2 0,527 (Drosophila) CDNA clone IMAGE:517556 0,0053412 0,3267775 25,2 47,9 0,526 5 mitogen- activated protein kinase kinase kinase 7 interacting 0,0106868 0,3795799 30,8 58,6 0,526 protein 3 mitochondrial ribosomal 0,0117692 0,3891601 411 780,7 0,526 protein S18B CDNA FLJ14144 fis, clone MAMMA10029 0,0183356 0,4368809 32,9 62,6 0,526 09 0,0270526 0,4727831 348,8 663,3 0,526 jun oncogene cornichon homolog 4 0,0385413 0,5072367 483,9 920,5 0,526 (Drosophila) HLA-B associated 182 0,0005609 0,1940962 197 375 0,525 transcript 4 mitochondrial ribosomal 0,0017966 0,2490398 146,4 278,8 0,525 protein L10 Nipped-B homolog 0,0116596 0,3891601 87,6 167 0,525 (Drosophila)

nucleoside 0,0160655 0,4211937 666,2 1269,4 0,525 phosphorylase polymerase (RNA) I polypeptide B, 0,0184742 0,4377222 46,8 89,1 0,525 128kDa interferon gamma 0,0463341 0,5194416 82,7 157,4 0,525 receptor 1 leucine rich repeat containing 8 family, member 0,0122426 0,3928661 81 154,6 0,524 A 0,0237272 0,4633196 34,7 66,2 0,524 zinc finger 0,0355372 0,4984838 230,4 440,1 0,524 protein 330 FGFR1 oncogene 0,0374045 0,5048361 92 175,7 0,524 partner 2 nuclear factor of activated T- cells, cytoplasmic, calcineurin- 0,0398627 0,5087876 83,8 159,9 0,524 dependent 3 poly(A) polymerase 0,0441192 0,5145349 167,3 319,1 0,524 alpha Transcribed 0,0026208 0,2797591 28,1 53,7 0,523 locus ubiquitin specific 0,009584 0,3688312 32,3 61,8 0,523 peptidase 53 cholesterol 25- 0,0184907 0,4377289 671,7 1285,2 0,523 hydroxylase coiled-coil domain 0,0218952 0,4540657 30,1 57,6 0,523 containing 77 component of oligomeric golgi complex 0,0244535 0,4660137 140,6 268,7 0,523 2 cornichon homolog 4 0,0276154 0,4740571 1663,6 3180,7 0,523 (Drosophila)

zinc finger and BTB domain 0,0334001 0,493712 16,9 32,3 0,523 containing 44 CDNA clone IMAGE:482080 0,0493922 0,5248641 14,9 28,5 0,523 9 lactate dehydrogenas 0,0015726 0,2418041 11,9 22,8 0,522 e A-like 6B forkhead box 0,0032864 0,3012437 161,4 309,1 0,522 O3 Nipped-B homolog 0,0040334 0,3147127 45,1 86,4 0,522 (Drosophila) discs, large homolog 1 0,0103247 0,3766691 36,2 69,3 0,522 (Drosophila) KIAA1627 0,016802 0,4260897 133 254,6 0,522 protein ligand dependent nuclear receptor corepressor- 0,0230183 0,4616748 72,4 138,8 0,522 like 0,0237753 0,4633196 66,7 127,8 0,522 Sorting nexin 5

polymerase (DNA directed) 0,0376265 0,50642 96 184 0,522 kappa zinc finger, RAN-binding domain 223 0,0001859 0,1563705 358,1 687,2 0,521 containing 2 Transcribed 0,0012264 0,2280729 107 205,3 0,521 locus Full-length cDNA clone CS0DF030YM 05 of Fetal brain of Homo sapiens 0,0056384 0,3288602 84,2 161,7 0,521 (human)

methyl-CpG binding domain 0,0225735 0,4591785 54,2 104,1 0,521 protein 4 Lyrm7 homolog 0,0244063 0,4660137 54,8 105,2 0,521 (mouse)

jumonji domain 0,0372379 0,5034575 22,3 42,8 0,521 containing 1C chromosome 14 open reading frame 0,0441266 0,5145349 82,3 157,9 0,521 130 deoxynucleotid yltransferase, terminal, interacting 0,0086078 0,3602917 609,5 1173,1 0,52 protein 2 gem (nuclear organelle) associated 0,0100577 0,3745852 51,5 99,1 0,52 protein 4 Muscleblind- like 0,0211582 0,4507588 46,7 89,8 0,52 (Drosophila) nucleoporin 0,0395369 0,5080329 126,9 244,2 0,52 85kDa protein associated with topoisomerase II homolog 1 0,042831 0,5127624 128,7 247,7 0,52 (yeast) protein regulator of 0,0011652 0,2260869 16,3 31,4 0,519 cytokinesis 1 kelch repeat and BTB (POZ) domain 0,0015204 0,2418041 32,4 62,4 0,519 containing 4 family with sequence similarity 44, 0,0015983 0,2418041 179,4 345,7 0,519 member A heterogeneous nuclear ribonucleoprot 0,0038006 0,3114214 452,4 872,3 0,519 ein H3 (2H9) GTPase, IMAP family member 0,0096103 0,3692503 12,5 24,1 0,519 6 centromere 0,0288623 0,4792123 12,1 23,3 0,519 protein Q tumor suppressor 0,0469985 0,521195 96,9 186,8 0,519 candidate 4 solute carrier family 35 (UDP- N- acetylglucosa mine (UDP- GlcNAc) transporter), 0,0035407 0,3039332 93 179,7 0,518 member A3 T-cell activation GTPase activating 0,0307701 0,4866502 104,7 202 0,518 protein oxoglutarate (alpha- ketoglutarate) dehydrogenas 111 0,0002115 0,1623024 96,1 186 0,517 e (lipoamide) Transcribed 0,0011503 0,2260869 59,4 114,9 0,517 locus

adaptor-related protein complex 4, 0,0017461 0,2455456 67,4 130,3 0,517 beta 1 subunit centaurin, 0,0060083 0,3320761 108,5 209,9 0,517 delta 1 zinc finger 0,0233186 0,4626778 47,7 92,3 0,517 protein 652

Mdm4, transformed 3T3 cell double minute 1, p53 binding protein 0,0399227 0,5087876 17,8 34,4 0,517 (mouse)

nudix (nucleoside diphosphate linked moiety 0,0038334 0,3114214 138,2 267,7 0,516 X)-type motif 1 MRNA; cDNA DKFZp547K18 9 (from clone DKFZp547K18 0,0045145 0,3197234 82,9 160,6 0,516 9) UHRF1 (ICBP90) binding protein 0,0130602 0,4026559 40,7 78,9 0,516 1-like keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et 0,0206973 0,4485902 140,7 272,9 0,516 plantaris) centaurin, beta 0,0346157 0,4968481 46 89,2 0,516 1 ATP-binding cassette, sub- family E (OABP), 0,0374455 0,5051321 254,9 494,3 0,516 member 1 acidic (leucine- rich) nuclear phosphoprotei n 32 family, 0,0067669 0,3434229 94,1 182,6 0,515 member E zinc finger CCCH-type 0,0091904 0,3683909 71,6 139 0,515 containing 8

tRNA methyltransfer ase 6 homolog 0,0190878 0,4414157 98,5 191,2 0,515 (S. cerevisiae) membrane- spanning 4- domains, subfamily A, 0,0392838 0,5080329 1611,5 3126,2 0,515 member 7 NFKB activating 0,0432181 0,5130413 69,1 134,1 0,515 protein

chromosome 1 open reading 157 0,0009417 0,2205071 43 83,6 0,514 frame 71

MRNA; cDNA DKFZp547K18 9 (from clone DKFZp547K18 0,0011194 0,2241875 84,1 163,5 0,514 9) RNA-binding region (RNP1, RRM) 0,003084 0,2932482 100,2 195 0,514 containing 3 Transcribed 0,0039371 0,3127885 11 21,4 0,514 locus SLAM family 0,0104692 0,3766691 176,3 343,3 0,514 member 9 mitogen- activated protein kinase kinase kinase 0,015952 0,4211374 68,6 133,4 0,514 2

0,0207346 0,4485902 112 217,7 0,514 CD1d molecule

retinoic acid 209 0,0005034 0,1940962 35,3 68,8 0,513 receptor, alpha ubiquitin specific 0,002801 0,2846759 111,7 217,8 0,513 peptidase 38 0,0058047 0,3304939 41,2 80,3 0,513 ATG16 autophagy related 16-like 2 (S. 0,0320912 0,4906561 52,9 103,1 0,513 cerevisiae) reticulon 4 interacting 0,0332869 0,493712 68,8 134,1 0,513 protein 1

ARP5 actin- related protein 5 homolog 0,001615 0,2418041 21,7 42,4 0,512 (yeast)

TRM5 tRNA methyltransfer ase 5 homolog 0,0061883 0,3366906 53,8 105,1 0,512 (S. cerevisiae) mitochondrial ribosomal 0,0135564 0,4041641 665,2 1299,7 0,512 protein L47 0,0300952 0,4831048 50,3 98,3 0,512

chromosome 3 open reading 0,0434209 0,5133055 84,4 164,8 0,512 frame 63 Rab geranylgeranyl transferase, 0,0015065 0,2418041 427,8 837,4 0,511 beta subunit 0,003141 0,2971525 476,4 932,3 0,511 vimentin 0,0055987 0,3279506 456,6 893 0,511 jun oncogene

DEAD (Asp- Glu-Ala-Asp) box 0,0100965 0,3747632 136,4 266,8 0,511 polypeptide 42 Transcribed 0,0242552 0,4656436 212,6 416,3 0,511 locus origin recognition complex, subunit 4-like 0,026111 0,4702698 235,4 460,3 0,511 (yeast) transmembran e and coiled- coil domain 0,0295454 0,4819829 23,2 45,4 0,511 family 1 phospholipase A2, group IVA (cytosolic, calcium- 0,0454958 0,5172371 178,2 349 0,511 dependent) centromere 0,0457784 0,5177385 11,2 21,9 0,511 protein J myeloid/lymph oid or mixed- lineage 18 0,0006874 0,2063309 235,4 461,5 0,51 leukemia 3 hypothetical protein 0,0022312 0,2675238 50,6 99,2 0,51 MGC16385 zinc finger 0,0052958 0,3267775 54 105,9 0,51 protein 317

Mdm2, transformed 3T3 cell double minute 2, p53 binding protein 0,0120805 0,3916465 18,2 35,7 0,51 (mouse) flap structure- specific endonuclease 0,0252952 0,4702698 50,3 98,7 0,51 1 tubulin, gamma complex associated 0,0257273 0,4702698 10,5 20,6 0,51 protein 3

UTP11-like, U3 small nucleolar ribonucleoprot 0,0269505 0,4727831 176,6 346,3 0,51 ein, (yeast) 0,0372247 0,5034035 114,1 223,9 0,51 thymopoietin hypothetical protein 0,045802 0,5177385 24,8 48,6 0,51 FLJ32549 proteasome (prosome, macropain) activator 0,0468972 0,5209477 69 135,4 0,51 subunit 4

human immunodeficie ncy virus type I enhancer binding protein 0,0027307 0,2846641 64,8 127,3 0,509 1 Transcribed 0,004386 0,3197234 23,9 47 0,509 locus FIP1 like 1 (S. 62 0,00035 0,1819093 18,6 36,6 0,508 cerevisiae) Cytoplasmic linker associated 256 0,0005732 0,1948388 36 70,9 0,508 protein 1 Transcribed 53 0,0006205 0,1980347 58,1 114,4 0,508 locus zinc ribbon domain 85 0,0007944 0,2088164 151,6 298,2 0,508 containing 1 chromosome 11 open reading frame 0,0054132 0,3274124 45,7 90 0,508 30 DNA methyltransfer ase 1 associated 0,0191901 0,4417307 114,4 225,1 0,508 protein 1 0,0371738 0,5033373 43,9 86,5 0,508 syntaxin 16

N- ethylmaleimide- sensitive factor attachment protein, 0,0438323 0,5143739 86,8 171 0,508 gamma RAN binding 221 0,0001956 0,1581555 85,6 169 0,507 protein 2 activating transcription 265 0,0003755 0,1824597 187,3 369,3 0,507 factor 1 WD repeat 61 0,0004391 0,1940962 77,4 152,6 0,507 domain 75 component of oligomeric golgi complex 0,0011485 0,2260869 21,6 42,6 0,507 3 CDK5 regulatory subunit associated 0,0094477 0,3688312 138,8 273,5 0,507 protein 1

DEAD (Asp- Glu-Ala-Asp) box 0,010248 0,3757944 286,1 563,9 0,507 polypeptide 18 MIS12, MIND kinetochore complex component, homolog 0,0109662 0,3829822 192,5 379,5 0,507 (yeast)

heat shock 60kDa protein 0,0197336 0,4458817 10,8 21,3 0,507 1 (chaperonin)

chromosome 4 open reading 0,0256522 0,4702698 106,1 209,3 0,507 frame 27 0,0456642 0,5177385 77,3 152,5 0,507 calpain 7 Transcribed locus, moderately similar to XP_517655.1 PREDICTED: similar to KIAA0825 protein [Pan 106 0,0002682 0,1708912 12,1 23,9 0,506 troglodytes] choroideremia- like (Rab escort protein 100 0,0004378 0,1940962 90,7 179,2 0,506 2) BCL2- associated transcription 0,0029339 0,2895505 38,7 76,5 0,506 factor 1

chromosome 8 open reading 0,0059225 0,3307586 70,7 139,8 0,506 frame 41 membrane- spanning 4- domains, subfamily A, 0,0098668 0,3706297 2014,8 3980,4 0,506 member 7 TNFAIP3 interacting 0,0315381 0,4886216 404,9 799,6 0,506 protein 3 0,0458254 0,5178801 382,3 755,1 0,506 glypican 4 mitochondrial translational release factor 20 0,0005397 0,1940962 9,9 19,6 0,505 1 aryl hydrocarbon 0,0147925 0,4119489 679,6 1344,5 0,505 receptor CDNA FLJ42306 fis, clone TRACH200164 0,0214521 0,4522939 115,3 228,5 0,505 6 sarcoma antigen NY- 0,0342926 0,4961507 46,1 91,2 0,505 SAR-48 hypothetical protein 0,0386615 0,5072367 39 77,3 0,505 LOC643641 0,0407747 0,5112983 113,9 225,5 0,505 kelch repeat and BTB (POZ) domain 137 0,0005527 0,1940962 57,5 114,1 0,504 containing 4 zinc finger, SWIM-type 255 0,0005927 0,1949966 661,3 1313,3 0,504 containing 6 SMAD family 0,0010329 0,2205294 41 81,4 0,504 member 5 structural maintenance of chromosomes flexible hinge domain 0,0066197 0,3412079 274,2 544,4 0,504 containing 1

Mdm2, transformed 3T3 cell double minute 2, p53 binding protein 0,0089875 0,3639938 151,7 301,1 0,504 (mouse) solute carrier family 25, 0,0204351 0,4485902 113,2 224,5 0,504 member 37 Synaptotagmin 0,0470176 0,521195 13,1 26 0,504 XV PHD finger 0,0484769 0,5225078 56,4 112 0,504 protein 14 RAD18 homolog (S. 215 0,0003251 0,1765299 15,1 30 0,503 cerevisiae) structural maintenance of chromosomes flexible hinge domain 0,0030973 0,2940015 244,6 485,8 0,503 containing 1 v-ets erythroblastosi s virus E26 oncogene homolog 2 0,0041179 0,3163535 167,5 333 0,503 (avian) Chromobox homolog 3 (HP1 gamma homolog, 0,0043807 0,3197234 14,6 29 0,503 Drosophila) HscB iron- sulfur cluster co-chaperone homolog (E. 0,0137083 0,4046068 98,4 195,5 0,503 coli)

signal transducing adaptor molecule (SH3 domain and 0,0158963 0,4199568 133,1 264,6 0,503 ITAM motif) 1 hypothetical 0,0252127 0,4702698 8,8 17,5 0,503 LOC644285 NIF3 NGG1 interacting factor 3-like 1 0,0266453 0,472096 94,8 188,3 0,503 (S. pombe) chromosome 12 open reading frame 0,0302743 0,4840192 29,8 59,2 0,503 35

Homo sapiens, clone IMAGE:54977 0,0457591 0,5177385 18,5 36,8 0,503 23, mRNA non-SMC condensin II complex, 227 0,0001047 0,1541482 22,6 45 0,502 subunit G2 Activating transcription factor 7 interacting 86 0,0007834 0,2088164 183,8 366 0,502 protein 2 centromere protein E, 0,0027045 0,2846641 16,2 32,3 0,502 312kDa nudix (nucleoside diphosphate linked moiety X)-type motif 0,0052762 0,3267775 85,1 169,6 0,502 21 family with sequence similarity 29, 0,0076231 0,3505421 36,5 72,7 0,502 member A glioma tumor suppressor candidate 0,0124904 0,3964301 481,7 959,9 0,502 region gene 2 MAX dimerization 0,0260043 0,4702698 84,9 169 0,502 protein 1 tryptase 0,0313791 0,4885021 39,4 78,5 0,502 alpha/beta 1

lin-37 homolog 0,0314898 0,4885675 64,1 127,7 0,502 (C. elegans) 0,0011633 0,2260869 42,1 84,1 0,501 KIAA1333 KIAA1648 0,0042328 0,3196524 25 49,9 0,501 protein

U2-associated 0,0080094 0,3545654 103,2 206 0,501 SR140 protein

chromosome 8 open reading 0,0230002 0,4616505 29,8 59,5 0,501 frame 59 Mortality factor 0,0306527 0,4862003 80 159,7 0,501 4 like 2 ribosomal 0,0014115 0,241168 2840,8 5684,9 0,5 protein S6 zinc finger 0,0080492 0,3551977 15 30 0,5 protein 684 eukaryotic translation initiation factor 0,0144073 0,4089197 83,6 167,1 0,5 4B mediator of DNA damage 0,0232509 0,4625449 46,3 92,6 0,5 checkpoint 1 amyloid beta precursor protein (cytoplasmic tail) binding 0,0039436 0,3127885 33,7 67,5 0,499 protein 2

chromosome 6 open reading 0,0057052 0,3304362 17,5 35,1 0,499 frame 199 mediator complex 0,011579 0,388941 84,3 169,1 0,499 subunit 23 yippee-like 3 0,042986 0,5129646 70,6 141,5 0,499 (Drosophila) Transcribed 0,0023783 0,2714688 65,7 132 0,498 locus 0,0025254 0,2756013 54,8 110 0,498 OTU domain 0,0053289 0,3267775 577,6 1160,3 0,498 containing 1 forkhead box 0,0083222 0,3573101 185,1 371,6 0,498 O3 chromosome 14 open reading frame 0,0089151 0,3635583 128,2 257,4 0,498 138 dachsous 1 0,0123067 0,3932606 37,6 75,5 0,498 (Drosophila) membrane- associated ring finger (C3HC4) 30 0,0002267 0,16423 330,3 664,8 0,497 6 polycomb group ring 0,0011472 0,2260869 100,8 203 0,497 finger 1 Transcribed 0,005742 0,3304939 28,8 57,9 0,497 locus apolipoprotein 0,0081163 0,3561466 267,3 538,3 0,497 O Mediator complex 0,0318594 0,4894884 31,4 63,2 0,497 subunit 26

solute carrier family 22 (organic cation transporter), 0,0326395 0,4928929 35,5 71,4 0,497 member 15

small nucleolar RNA host gene (non-protein 251 0,0006411 0,1980347 90,3 182,1 0,496 coding) 7 structural maintenance of chromosomes 0,0061088 0,3358513 126,2 254,2 0,496 3 family with sequence similarity 8, 0,0084789 0,3591295 202,6 408,3 0,496 member A1

MRNA; cDNA DKFZp451O24 9 (from clone DKFZp451O24 0,008884 0,3635583 86,7 174,8 0,496 9)

multiple EGF- 0,012314 0,393264 30,6 61,7 0,496 like-domains 9 SUMO1/sentri n specific 0,0013075 0,2351565 58,1 117,4 0,495 peptidase 6 ubiquitin specific 0,0029585 0,2896601 122,1 246,5 0,495 peptidase 47 geminin, DNA replication 0,014319 0,4083537 74,4 150,2 0,495 inhibitor yippee-like 4 0,0169519 0,426752 41,3 83,4 0,495 (Drosophila) CDNA FLJ11757 fis, clone HEMBA10056 0,0321891 0,4912811 135,4 273,3 0,495 06 42 0,0009518 0,2205071 36,8 74,5 0,494 KIAA1712 0,0092948 0,3687888 35,5 71,8 0,494 rotatin heat shock protein 90kDa alpha (cytosolic), class B 0,0148776 0,4124913 1573 3182,5 0,494 member 1 chromosome 17 open reading frame 0,0150171 0,4143327 46,9 95 0,494 44 Fanconi anemia, complementati 0,0287929 0,4791082 101,6 205,7 0,494 on group D2 CDNA clone IMAGE:479305 8 0,000135 0,1541482 158,4 321,5 0,493 8 FGFR1 oncogene 67 0,0001804 0,1562509 102,9 208,9 0,493 partner 2 ankyrin repeat 0,0019 0,2536814 18,6 37,7 0,493 domain 32 zinc finger E- box binding 0,0044913 0,3197234 69,5 141 0,493 homeobox 2 replication factor C (activator 1) 5, 0,0080132 0,3545654 18,4 37,3 0,493 36.5kDa CDNA FLJ31332 fis, clone MAMGL10000 0,008212 0,3566213 68 138 0,493 96 G patch domain 0,0158665 0,4196703 39,6 80,3 0,493 containing 1 Protein geranylgeranyl transferase type I, beta 0,0187913 0,4401921 105,2 213,3 0,493 subunit angiotensin II receptor- associated 0,0269976 0,4727831 168,8 342,1 0,493 protein carboxypeptida 0,031737 0,4894884 337,4 684,2 0,493 se D cancer susceptibility 25 0,0003092 0,1742973 121,4 246,5 0,492 candidate 3 myosin, light chain 6B, alkali, smooth muscle and 0,0027084 0,2846641 104,6 212,6 0,492 non-muscle MRNA from chromosome 5q21-22, 0,0028006 0,2846759 36,8 74,8 0,492 clone:357Ex SCL/TAL1 interrupting 0,0061218 0,3358513 45,7 92,8 0,492 locus Josephin domain 0,0062452 0,3373399 459,6 933,4 0,492 containing 3 PAN2 polyA specific ribonuclease subunit homolog (S. 0,0109911 0,3829822 75,6 153,6 0,492 cerevisiae)

Fibronectin type III domain 0,0302687 0,4840192 495 1007 0,492 containing 3B elongation protein 3 homolog (S. 0,0444281 0,5146943 97,7 198,7 0,492 cerevisiae) Josephin domain 87 0,0007797 0,2088164 455,5 927,4 0,491 containing 3 transmembran e protein 29 /// transmembran 0,0064894 0,3398648 160,2 326,5 0,491 e protein 29B transmembran 0,0132982 0,4038543 94 191,6 0,491 e protein 68 zinc finger 0,0197647 0,4458817 144,6 294,5 0,491 protein 791 peptidylprolyl isomerase (cyclophilin)- 0,0204595 0,4485902 159,7 325,2 0,491 like 5 protein phosphatase 4, regulatory 0,023663 0,4633196 121,4 247,3 0,491 subunit 2 PX domain containing serine/threonin 0,0354475 0,4984838 47,1 96 0,491 e kinase

LysM, putative peptidoglycan- binding, domain 0,0409414 0,5113922 388,7 792 0,491 containing 2 poly (ADP- ribose) polymerase family, member 162 0,0006364 0,1980347 101,3 206,8 0,49 2 PHD finger 132 0,0009044 0,2205071 80 163,4 0,49 protein 3 Ras-related associated 0,0025057 0,2756013 22,6 46,1 0,49 with diabetes

neutrophil cytosolic factor 0,0065693 0,3412079 178,9 364,9 0,49 4, 40kDa prenyl (decaprenyl) diphosphate synthase, 0,0463914 0,5195514 43,4 88,5 0,49 subunit 2 Josephin domain 0,0058669 0,3307111 81,9 167,5 0,489 containing 3

tankyrase, TRF1- interacting ankyrin-related ADP-ribose 0,0140213 0,4066921 30,7 62,8 0,489 polymerase proliferating cell nuclear 0,0399745 0,5087876 257,4 526 0,489 antigen hypothetical gene supported by 0,0010403 0,2205294 29,7 60,8 0,488 BC009385 CDNA clone IMAGE:526869 0,0046612 0,3197234 28 57,4 0,488 6

Chromosome 1 open reading 0,011073 0,3843913 75,1 154 0,488 frame 58 mago-nashi homolog, proliferation- associated 0,0172417 0,4296992 153 313,5 0,488 (Drosophila) keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et 0,0264059 0,4710324 282,4 578,4 0,488 plantaris)

hexamethylene bis-acetamide 261 0,0004976 0,1940962 169,2 347,1 0,487 inducible 1 metal response element binding transcription 0,008396 0,3576553 353 725,2 0,487 factor 2

centrosomal 0,040801 0,5112983 264,2 542,5 0,487 protein 164kDa replication factor C (activator 1) 3, 260 0,0005075 0,1940962 28,7 59,1 0,486 38kDa

primase, DNA, polypeptide 2 0,0033889 0,3039332 8,4 17,3 0,486 (58kDa) ribosomal 0,0082961 0,3568017 46,4 95,5 0,486 protein L37a ESF1, nucleolar pre- rRNA processing protein, homolog (S. 0,0177338 0,4331491 32,7 67,3 0,486 cerevisiae) sulfiredoxin 1 homolog (S. 0,0206875 0,4485902 1312,6 2701,5 0,486 cerevisiae) CDNA FLJ13202 fis, clone NT2RP300450 0,0213094 0,4517609 39,1 80,5 0,486 3 flap structure- specific endonuclease 0,0328403 0,493025 85,8 176,5 0,486 1 Chromosome 13 open reading frame 268 0,0001367 0,1541482 66 136,1 0,485 15 chromosome 21 open reading frame 0,003432 0,3039332 37,8 77,9 0,485 66 hypothetical protein 0,0037666 0,3114214 65,1 134,1 0,485 LOC286052

centrosomal 0,0103813 0,3766691 30 61,9 0,485 protein 152kDa Transcribed 0,0259706 0,4702698 29,9 61,6 0,485 locus hypothetical 0,0337535 0,4946955 157,2 324 0,485 LOC401317

suppressor of Ty 16 homolog 0,0019796 0,2562745 103,1 213 0,484 (S. cerevisiae) ubiquitin specific 0,0035422 0,3039332 238 492,1 0,484 peptidase 1 ceroid- lipofuscinosis, neuronal 8 (epilepsy, progressive with mental 0,0055732 0,3279506 175,5 362,7 0,484 retardation)

cytochrome b5 0,0079153 0,3544382 39,6 81,9 0,484 reductase 2 intraflagellar transport 80 homolog (Chlamydomon 0,0129839 0,401446 19,8 40,9 0,484 as) CDNA: FLJ23242 fis, clone 0,0424778 0,5127624 90 185,8 0,484 COL01514 transcription factor A, 34 0,00014 0,1541482 49,1 101,6 0,483 mitochondrial 0,0012082 0,2277874 25,5 52,8 0,483 KIAA1333 H2A histone family, member 0,0013215 0,2367106 1575,2 3262,7 0,483 Z zinc finger E- box binding 0,0027137 0,2846641 287,2 594,7 0,483 homeobox 2 Transcribed 0,0040255 0,3147127 32,2 66,7 0,483 locus Rap guanine nucleotide exchange 0,0082315 0,3566213 235,9 488,1 0,483 factor (GEF) 6

signal-induced proliferation- associated 1 0,0125122 0,3964301 223,5 462,7 0,483 like 2 mitochondrial ribosomal 0,0430842 0,5129646 239,9 496,7 0,483 protein L42 integrator complex 160 0,0007906 0,2088164 54,6 113,2 0,482 subunit 7 RAB11 family interacting protein 2 (class 0,0033398 0,3038329 112,4 233,3 0,482 I) chromosome 13 open reading frame 0,0083985 0,3576553 95,2 197,5 0,482 23 guanine monphosphate 0,0148067 0,4119489 176,4 365,9 0,482 synthetase Protein phosphatase 1, regulatory (inhibitor) 218 0,0002989 0,1742973 43,1 89,6 0,481 subunit 3E 0,0032716 0,3011359 65,3 135,8 0,481 CDNA FLJ37019 fis, clone BRACE201066 0,0047637 0,3199091 57 118,6 0,481 9 basic helix- loop-helix domain containing, 0,0117244 0,3891601 112,5 233,9 0,481 class B, 2 retinitis pigmentosa GTPase 0,014082 0,4075754 32,1 66,8 0,481 regulator solute carrier family 24 (sodium/potass ium/calcium exchanger), 0,0259615 0,4702698 28,4 59 0,481 member 4

chromosome 9 open reading 0,0481364 0,5224951 143,1 297,4 0,481 frame 6 ceroid- lipofuscinosis, neuronal 8 (epilepsy, progressive with mental 0,0499103 0,5253842 55,7 115,9 0,481 retardation) chromosome 6 open reading 0,0013807 0,238971 34,8 72,5 0,48 frame 136 Chromosome 21q22.1 anonymous mRNA 0,003446 0,3039332 57,9 120,5 0,48 sequence

CSRP2 0,0086504 0,3602917 61,8 128,7 0,48 binding protein phospholipase 0,0088216 0,3626474 46,7 97,3 0,48 C-like 2

DEAD (Asp- Glu-Ala-Asp) box 0,0412541 0,5116636 103,3 215,1 0,48 polypeptide 18 nuclear receptor subfamily 4, group A, 0,0445026 0,5147869 53,8 112 0,48 member 2 hypothetical protein 0,0015261 0,2418041 28,4 59,3 0,479 LOC202781 zinc finger 0,0023695 0,2714688 62,4 130,4 0,479 protein 45 aurora kinase 0,0027106 0,2846641 28,7 59,9 0,479 A heat shock 70kDa protein 0,0105702 0,3777292 109,4 228,5 0,479 6 (HSP70B') FXYD domain containing ion transport 0,0237814 0,4633196 45,3 94,5 0,479 regulator 2 vav 1 guanine nucleotide exchange 63 0,0003375 0,1791535 166,9 349 0,478 factor topoisomerase (DNA) II binding protein 205 0,0005773 0,1948388 205,9 431,2 0,478 1 DnaJ (Hsp40) homolog, subfamily B, 0,0085082 0,3591295 50,2 105 0,478 member 5 chromosome 18 open reading frame 0,0219323 0,454395 187 391,2 0,478 21 Dedicator of 0,0247781 0,4669916 201,8 421,8 0,478 cytokinesis 5 mitochondrial ribosomal 0,02541 0,4702698 49,2 103 0,478 protein S9 tissue factor pathway inhibitor (lipoprotein- associated coagulation 0,0422604 0,5127624 39,9 83,4 0,478 inhibitor) intraflagellar transport 80 homolog (Chlamydomon 0,0042869 0,3197234 20,9 43,8 0,477 as) structural maintenance of chromosomes 0,00437 0,3197234 17,6 36,9 0,477 3 transformation/ transcription domain- associated 0,0062235 0,3372347 55,4 116,2 0,477 protein DNA-damage- inducible 0,0201571 0,4477043 122,7 257,5 0,477 transcript 4 CDNA FLJ27143 fis, clone 114 0,000152 0,1541482 75,6 158,9 0,476 SPL09242

dual-specificity tyrosine-(Y)- phosphorylatio n regulated 0,0156094 0,4179451 25,9 54,4 0,476 kinase 2 Transcribed 0,0237483 0,4633196 45,7 96 0,476 locus

110 0,0002148 0,1623024 35,9 75,5 0,475 F-box protein 5 multiple C2 domains, transmembran 254 0,0005944 0,1949966 20,2 42,5 0,475 e 2 AF4/FMR2 family, member 0,0205455 0,4485902 90 189,3 0,475 4

RAD23 homolog B (S. cerevisiae) /// similar to UV excision repair protein RAD23 homolog B (hHR23B) (XP- C repair- complementing complex 58 kDa protein) 0,043129 0,5129646 17,7 37,3 0,475 (p58) Cbp/p300- interacting transactivator, with Glu/Asp- rich carboxy- terminal 0,0053049 0,3267775 414,3 874,7 0,474 domain, 2 CDNA FLJ43545 fis, clone PROST201163 0,0061871 0,3366906 131,6 277,4 0,474 1 structural maintenance of chromosomes flexible hinge domain 0,0135463 0,4041641 46,6 98,3 0,474 containing 1

chromosome 2 open reading 0,0308787 0,4870313 52,8 111,5 0,474 frame 64 tissue factor pathway inhibitor (lipoprotein- associated coagulation 0,0409772 0,5113922 55,7 117,4 0,474 inhibitor) Transcribed 0,0117702 0,3891601 87,3 184,6 0,473 locus solute carrier family 25, 0,0257852 0,4702698 16,5 34,9 0,473 member 37 tissue factor pathway inhibitor (lipoprotein- associated coagulation 0,0409049 0,5113922 178,5 377,5 0,473 inhibitor) seven in absentia homolog 1 0,0426686 0,5127624 79,7 168,5 0,473 (Drosophila) hypothetical gene supported by 0,0463204 0,5193946 54,5 115,3 0,473 BC040598 chemokine (C- C motif) 0,0180725 0,4355503 483,1 1023,8 0,472 receptor 1

signal-induced proliferation- associated 1 0,025083 0,469662 457,3 968,2 0,472 like 2 deleted in lymphocytic leukemia, 2 /// deleted in lymphocytic 0,0355235 0,4984838 11,1 23,5 0,472 leukemia 2-like Transcribed 0,0045694 0,3197234 42,5 90,3 0,471 locus WD repeats and SOF1 domain 0,0069941 0,3458012 282,3 599,5 0,471 containing

coiled-coil domain 0,0201885 0,4479733 57,4 121,9 0,471 containing 126

dual specificity 0,0298967 0,4826515 271,5 577 0,471 phosphatase 1 solute carrier family 25, 0,0305243 0,4852911 48,2 102,4 0,471 member 37 hypothetical protein 0,0494918 0,5248641 98 207,9 0,471 FLJ90709 minichromoso me maintenance complex 0,0071279 0,3458012 53,7 114,3 0,47 component 7

Full-length cDNA clone CS0DI039YF1 2 of Placenta Cot 25- normalized of Homo sapiens 0,0074161 0,3504479 72,5 154,1 0,47 (human)

PMS1 postmeiotic segregation increased 1 (S. 0,0329738 0,4934061 46,2 98,2 0,47 cerevisiae) Kruppel-like 0,0425893 0,5127624 169,7 360,7 0,47 factor 9

SNF2 histone linker PHD 231 8,01E-05 0,1541482 27,8 59,3 0,469 RING helicase homeodomain interacting protein kinase 49 0,0007331 0,2087617 65,8 140,2 0,469 1 dehydrogenas e/reductase (SDR family) 0,0390183 0,5080329 411,5 877,7 0,469 member 9 RNA binding motif protein 0,001024 0,2205294 23,3 49,8 0,468 12B coiled-coil domain 0,0044886 0,3197234 52,6 112,3 0,468 containing 76 hypothetical 0,0122728 0,3928661 83,8 178,9 0,468 LOC645460 gem (nuclear organelle) associated 0,0126012 0,3972882 71,4 152,5 0,468 protein 6 Muscleblind- like 2 0,0199925 0,4476045 62 132,6 0,468 (Drosophila) brix domain 0,0043168 0,3197234 529,9 1134 0,467 containing 5 metal response element binding transcription 0,0231291 0,4619618 43,2 92,5 0,467 factor 2 solute carrier family 7 (cationic amino acid transporter, y+ system), 0,0234226 0,4629012 242,3 518,3 0,467 member 8 peroxiredoxin 0,0108135 0,3811916 289,2 620,6 0,466 2 Transcribed 0,0271512 0,4727831 35,4 75,9 0,466 locus Full length insert cDNA clone 0,02929 0,4812171 10,4 22,3 0,466 ZD45C02 THUMP domain 58 0,0005095 0,1940962 41,2 88,6 0,465 containing 3 Hypothetical protein 56 0,0005365 0,1940962 312,2 671 0,465 LOC149478 origin recognition complex, subunit 4-like 0,0054996 0,3279506 17,7 38,1 0,465 (yeast)

methyl-CpG binding domain 0,0065362 0,3412079 217,5 467,5 0,465 protein 4

transducin-like enhancer of split 4 (E(sp1) homolog, 0,0077154 0,3505421 92,7 199,4 0,465 Drosophila) chemokine (C- C motif) 0,0140632 0,4072592 26,4 56,8 0,465 receptor 3 solute carrier family 7 (cationic amino acid transporter, y+ system), 0,0229846 0,461565 83,9 180,6 0,465 member 8 Transcribed 0,0304137 0,4848015 32 68,8 0,465 locus peptidylprolyl isomerase domain and WD repeat 156 0,0009697 0,2205294 132,3 285 0,464 containing 1 cryptochrome 1 (photolyase- 4 0,0009734 0,2205294 99,1 213,7 0,464 like)

polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa pseudogene /// DNA directed RNA polymerase II polypeptide J- related /// PMS2 postmeiotic segregation increased 2 (S. cerevisiae)-like /// similar to postmeiotic segregation increased 2- 0,0104578 0,3766691 348,6 752 0,464 like 2

Homo sapiens, clone IMAGE:42848 50, mRNA /// CDNA FLJ39749 fis, clone SMINT201759 0,0105686 0,3777292 65,6 141,3 0,464 9 centrosomal 0,0427693 0,5127624 31,9 68,8 0,464 protein 76kDa cytoskeleton- associated 0,0483657 0,5225078 424,1 914,5 0,464 protein 4 SFRS12- interacting 200 0,000719 0,2084556 59,2 127,9 0,463 protein 1 downstream neighbor of 0,007061 0,3458012 68,5 147,9 0,463 SON cytotoxic and regulatory T 0,0254653 0,4702698 47,4 102,4 0,463 cell molecule kelch repeat and BTB (POZ) domain containing 4 /// protein tyrosine phosphatase, 0,0035973 0,3049339 80,6 174,5 0,462 mitochondrial 1

zinc finger and BTB domain 0,0051106 0,3258567 98,4 212,8 0,462 containing 44

ribosomal protein L17 /// similar to 60S ribosomal protein L17 (L23) /// hCG39912 /// hypothetical LOC643863 /// hCG2004593 /// similar to 60S ribosomal protein L17 (L23) (Amino acid starvation- induced 0,0053038 0,3267775 105 227,4 0,462 protein) (ASI) activating transcription 0,0099438 0,3723817 46,7 101 0,462 factor 1 FAST kinase 0,0127413 0,4001324 134,2 290,4 0,462 domains 1 transcription termination factor, RNA 0,0435533 0,5138707 187 405,1 0,462 polymerase I tyrosyl-DNA phosphodieste 0,0440309 0,5143995 137,3 297 0,462 rase 1

translocated promoter region (to activated MET 0,0037893 0,3114214 17,7 38,4 0,461 oncogene) Transcribed 0,0053572 0,3267775 62,1 134,8 0,461 locus EF-hand domain (C- terminal) 0,0120607 0,3915788 20,8 45,1 0,461 containing 1 hypothetical protein 0,0245307 0,4660137 42,3 91,8 0,461 LOC285181 CDNA FLJ11971 fis, clone HEMBB10012 0,0313818 0,4885021 144,9 314,5 0,461 08 Full length insert cDNA 0,0016754 0,2418041 24 52,2 0,46 YH97B03 SCO cytochrome oxidase deficient homolog 2 0,0420034 0,5123056 528,5 1149,6 0,46 (yeast) SMAD family 226 0,0001111 0,1541482 60,7 132,3 0,459 member 5 structural maintenance of chromosomes 193 0,0008417 0,2147006 210,2 458,3 0,459 4 NLR family, pyrin domain 0,001971 0,2562745 31 67,5 0,459 containing 1 Transcribed 0,0129515 0,401446 17,4 37,9 0,459 locus 0,0225408 0,4589463 32,9 71,7 0,459 Rab geranylgeranyl transferase, 0,0085088 0,3591295 168,8 368,2 0,458 beta subunit nudix (nucleoside diphosphate linked moiety X)-type motif 0,0106419 0,3790527 29,7 64,8 0,458 15 family with sequence similarity 76, 0,0150812 0,4143327 96,5 210,5 0,458 member B

zinc finger and BTB domain 0,0255924 0,4702698 62,7 136,8 0,458 containing 44 coatomer protein complex, 0,0345183 0,4966548 197,1 430,8 0,458 subunit alpha cutC copper transporter homolog (E. 0,0463863 0,5195514 55,4 121 0,458 coli) RAN binding 222 0,0001912 0,1581555 270,3 591,3 0,457 protein 2 chromosome 10 open reading frame 0,0073237 0,3492431 96,6 211,5 0,457 4 component of oligomeric golgi complex 0,0448847 0,516331 95,1 208 0,457 6 Transcribed 0,0057123 0,3304939 61,7 135,2 0,456 locus 0,0070757 0,3458012 300,5 658,3 0,456

methyl-CpG binding domain 0,0122675 0,3928661 423,3 927,9 0,456 protein 4

Transcribed locus, strongly similar to XP_001172939 .1 PREDICTED: hypothetical protein [Pan 0,0229756 0,461565 26,2 57,5 0,456 troglodytes]

MRE11 meiotic recombination 11 homolog A 0,027396 0,4727831 60,9 133,6 0,456 (S. cerevisiae)

transducin-like enhancer of split 4 (E(sp1) homolog, 0,003498 0,3039332 89,5 196,7 0,455 Drosophila) ATG5 autophagy related 5 homolog (S. 0,0188754 0,4404183 27,6 60,6 0,455 cerevisiae) poly (ADP- ribose) polymerase family, member 22 0,0004218 0,1940962 96,4 212,3 0,454 2

zinc finger, CCHC domain 180 0,0006397 0,1980347 72,1 158,7 0,454 containing 6

TAF3 RNA polymerase II, TATA box binding protein (TBP)- associated 0,0011818 0,2275173 34,9 76,8 0,454 factor, 140kDa Wilms tumor 1 associated 0,0042843 0,3197234 85,4 187,9 0,454 protein cysteine-rich 0,0050872 0,3253354 116,5 256,6 0,454 PAK1 inhibitor chromosome 12 open reading frame 0,0156717 0,4190779 154,2 339,4 0,454 47 ClpX caseinolytic peptidase X homolog (E. 0,0136579 0,4046068 43 94,9 0,453 coli) UBX domain 0,0173275 0,4305249 58 128 0,453 containing 6 placenta- 0,0174069 0,4305249 60,5 133,6 0,453 specific 8 C-type lectin domain family 0,0182147 0,436017 18,9 41,7 0,453 2, member B

0,0025865 0,27948 16 35,4 0,452 F-box protein 5 ribonucleotide reductase M1 0,0046841 0,3197234 159,9 353,8 0,452 polypeptide ras homolog gene family, 0,0020998 0,2600279 59,1 131,1 0,451 member B pro-platelet basic protein (chemokine (C- X-C motif) 0,0142541 0,4080969 11,5 25,5 0,451 ligand 7) 0,0217553 0,4524803 48,8 108,1 0,451 Syncoilin, intermediate 0,003375 0,3039332 45,7 101,5 0,45 filament 1 IMP (inosine monophosphat e) dehydrogenas 0,0080349 0,3548531 316,1 703,1 0,45 e 2 zinc finger 9 6,53E-05 0,1541482 53,7 119,5 0,449 protein 146 nuclear receptor subfamily 1, group D, 198 0,0007244 0,2084556 39,7 88,4 0,449 member 2 zinc finger CCCH-type, 0,0021021 0,2600279 2330 5191 0,449 antiviral 1

SEC24 related gene family, member D (S. 0,0377641 0,5066876 100,9 224,6 0,449 cerevisiae) Transcribed 0,0071244 0,3458012 47,2 105,4 0,448 locus Transcribed 0,0089192 0,3635583 56,8 126,7 0,448 locus armadillo repeat containing, X- 0,0450115 0,516331 45,7 102 0,448 linked 5 coenzyme Q2 homolog, prenyltransfera 0,0232847 0,4625449 115,5 258,2 0,447 se (yeast) hypothetical protein 0,0069548 0,3458012 111,1 248,9 0,446 KIAA1434 SHQ1 homolog (S. 0,0091117 0,3671203 70,6 158,4 0,446 cerevisiae) Rho guanine nucleotide exchange factor (GEF) 0,0262175 0,4705663 28,3 63,4 0,446 10 Transcribed 0,026242 0,4705663 40,7 91,2 0,446 locus

chromosome 6 open reading 0,0354622 0,4984838 61,3 137,3 0,446 frame 130 cell division cycle 40 homolog (S. 0,0496387 0,5250037 39,8 89,3 0,446 cerevisiae) CCAAT/enhan cer binding 112 0,0002029 0,1607762 156,9 352,6 0,445 protein zeta

FK506 binding protein 14, 22 0,001685 0,2418041 43,8 98,5 0,445 kDa chromosome 15 open reading frame 0,0109913 0,3829822 107 240,3 0,445 21 DEAH (Asp- Glu-Ala-His) box 0,0164969 0,4244555 104,8 235,4 0,445 polypeptide 9 CDNA clone IMAGE:481821 0,0309324 0,4871177 44,5 100,1 0,445 1 BTB and CNC homology 1, basic leucine zipper transcription 0,0037747 0,3114214 81,4 183,5 0,444 factor 1 CDNA FLJ40827 fis, clone TRACH201150 0,0213803 0,451823 35,6 80,2 0,444 0 oxidation 0,0339549 0,4949661 31 69,8 0,444 resistance 1 mediator complex 0,0048678 0,3211399 192,1 433,3 0,443 subunit 6

translocated promoter region (to activated MET 225 0,0001294 0,1541482 16,7 37,8 0,442 oncogene) MYST histone acetyltransfera 105 0,000303 0,1742973 153,2 346,3 0,442 se 1 Transcribed 0,0016827 0,2418041 37,7 85,2 0,442 locus CDNA FLJ10182 fis, clone HEMBA10042 0,0041544 0,3163535 44,7 101,1 0,442 46 CDNA: FLJ23051 fis, clone 0,0155791 0,4179451 26,8 60,6 0,442 LNG02642 Zinc finger 0,0229337 0,461565 170 384,6 0,442 protein 638

dual specificity 0,0250746 0,469662 726,4 1644,3 0,442 phosphatase 6

chromosome 5 open reading 0,0355503 0,4984838 29,4 66,5 0,442 frame 28 hyaluronan- mediated motility receptor 26 0,0003067 0,1742973 17,4 39,5 0,441 (RHAMM) RAN binding 259 0,0005311 0,1940962 63,4 143,8 0,441 protein 2

chromosome 6 open reading 0,0071858 0,3462686 224,1 508,2 0,441 frame 173 RAN binding 229 8,81E-05 0,1541482 451,7 1027,7 0,44 protein 2 247 0,0008528 0,2148702 74,4 169,1 0,44 replication factor C (activator 1) 3, 0,0135391 0,4041641 55,8 126,8 0,44 38kDa WD repeat, sterile alpha motif and U- box domain 0,045343 0,516644 89 202,2 0,44 containing 1 Zwilch, kinetochore associated, homolog 161 0,0006878 0,2063309 131,6 300,1 0,439 (Drosophila) centrosome and spindle pole associated 0,0052297 0,3267775 14,8 33,7 0,439 protein 1 Kruppel-like 0,0075821 0,3505421 400,5 912,3 0,439 factor 4 (gut) FXYD domain containing ion transport 0,0121712 0,3928661 61,1 139,3 0,439 regulator 2 signal recognition particle receptor ('docking 0,0135815 0,4041641 198,4 452,2 0,439 protein') activating transcription 0,0147412 0,4118422 59,2 135 0,439 factor 1

Homo sapiens, clone IMAGE:52448 170 0,0001685 0,1541482 58,9 134,4 0,438 69, mRNA

v-fos FBJ murine osteosarcoma viral oncogene 0,0256844 0,4702698 187,6 428,1 0,438 homolog GA binding protein transcription factor, beta 0,0394009 0,5080329 55,9 127,7 0,438 subunit 2

primase, DNA, polypeptide 2 140 0,0005162 0,1940962 27,6 63,1 0,437 (58kDa) CDNA FLJ36574 fis, clone TRACH201237 0,0011661 0,2260869 33,8 77,4 0,437 6

DBF4 homolog 0,0029872 0,290098 75,3 172,4 0,437 (S. cerevisiae)

ATPase family, AAA domain 0,0054357 0,3274124 11,4 26,1 0,437 containing 2 Nipped-B homolog 0,0041006 0,3163535 69,3 158,9 0,436 (Drosophila) Transcribed 149 0,0001689 0,1541482 41,9 96,3 0,435 locus CDNA FLJ30967 fis, clone HEART200030 9, weakly similar to PTB- ASSOCIATED SPLICING 165 0,0005076 0,1940962 15,1 34,7 0,435 FACTOR poly(A) polymerase 0,0051386 0,3258567 22,6 51,9 0,435 gamma muscleblind- like 0,0209015 0,448736 471,5 1084,9 0,435 (Drosophila) 0,0085214 0,3592194 20,8 47,9 0,434 TatD DNase domain 0,0103896 0,3766691 171,6 395,6 0,434 containing 1 mitochondrial ribosomal 0,0143868 0,4088349 144,4 332,9 0,434 protein L1 Transcribed 0,0035537 0,3039332 185,4 428,5 0,433 locus zinc finger 0,0112654 0,3858197 43,7 100,9 0,433 protein 331 eukaryotic translation elongation factor 1 epsilon 0,0258506 0,4702698 104,9 242,9 0,432 1

U2-associated 144 0,000453 0,1940962 55,1 127,8 0,431 SR140 protein CDNA clone IMAGE:658432 0,0016173 0,2418041 89,5 207,6 0,431 6 CDNA clone IMAGE:527794 0,0122579 0,3928661 32,4 75,2 0,431 5

secretogranin 0,0144173 0,4089197 15,5 36 0,431 V (7B2 protein)

dual-specificity tyrosine-(Y)- phosphorylatio n regulated 0,0182868 0,4364168 18,5 42,9 0,431 kinase 2 bone morphogenetic 0,0262229 0,4705663 54 125,4 0,431 protein 6

DEAH (Asp- Glu-Ala-His) box 210 0,0004861 0,1940962 129,2 300,6 0,43 polypeptide 33

0,001528 0,2418041 94,3 219,1 0,43 integrin, beta 7 lipase A, lysosomal acid, cholesterol esterase (Wolman 0,023654 0,4633196 97,5 226,6 0,43 disease) 0,0020181 0,2572019 24,6 57,3 0,429 hypothetical 0,0037156 0,3106276 56,6 131,9 0,429 LOC339541 0,0064244 0,3395481 72,7 169,4 0,429 family with sequence similarity 29, 0,027375 0,4727831 30,5 71,1 0,429 member A TRAF3 interacting 0,030722 0,4863131 261,2 608,7 0,429 protein 2 adrenergic, beta-2-, receptor, 0,0360198 0,4990053 28,7 66,9 0,429 surface hypothetical protein 0,0035046 0,3039332 45,4 106,1 0,428 FLJ31033 Chromosome 13 open reading frame 0,0203391 0,4485902 56 130,7 0,428 15 pelota homolog 0,0011936 0,227535 166,6 389,9 0,427 (Drosophila) v-ets erythroblastosi s virus E26 oncogene homolog 2 0,0047148 0,3197234 92,4 216,4 0,427 (avian) Transcribed 0,0099787 0,3729224 58,7 137,6 0,427 locus transcription factor A, 0,0380208 0,5071739 97,6 228,4 0,427 mitochondrial kringle containing transmembran 0,0190561 0,4414157 38,6 90,7 0,426 e protein 1

leukocyte immunoglobuli n-like receptor, subfamily A (with TM domain), 0,0452974 0,5166257 65,7 154,1 0,426 member 1 0,0086633 0,3602917 55,4 130,5 0,425 claudin 23

TP53RK 0,0098955 0,3710812 425,8 1001,2 0,425 binding protein chromosome 10 open reading frame 0,0122386 0,3928661 87,7 206,5 0,425 54 CDNA FLJ38412 fis, clone FEBRA200938 0,025197 0,4702698 389 916,3 0,425 5 membrane- spanning 4- domains, subfamily A, 0,0254488 0,4702698 22,1 52,1 0,424 member 6E thrombomoduli 0,0322354 0,4912811 21,8 51,4 0,424 n 90 0,0007514 0,2088164 52,9 125 0,423 KIAA1333 TATA element modulatory 0,001449 0,2418041 65,3 154,2 0,423 factor 1 pellino homolog 1 0,0089797 0,3639938 767 1811,5 0,423 (Drosophila) copine VI 0,0098574 0,3706297 35,6 84,2 0,423 (neuronal) 0,0063196 0,3385624 89,3 211,4 0,422 KIAA0430 tryptase 0,0152965 0,415674 30,8 73 0,422 alpha/beta 1 DTW domain 0,0189524 0,4406633 46,8 110,9 0,422 containing 1 DIS3 mitotic control homolog (S. 118 8,98E-05 0,1541482 44,5 105,7 0,421 cerevisiae) basic helix- loop-helix domain containing, 0,0081426 0,3562602 29,1 69,2 0,421 class B, 3 Transcribed 0,0086814 0,3602917 22,8 54,1 0,421 locus 0,0392016 0,5080329 833,4 1981 0,421 fibronectin 1 Transcribed 0,0183678 0,4370146 34,5 82,1 0,42 locus ribosomal 148 0,0002403 0,16423 106,6 254,6 0,419 protein L31

processing of precursor 7, ribonuclease P/MRP subunit 177 0,0007669 0,2088164 87,9 209,6 0,419 (S. cerevisiae) tubulin, gamma complex associated 0,0020971 0,2600279 82,2 196,1 0,419 protein 3 Transcribed 0,0054043 0,3274124 43,9 104,7 0,419 locus vaccinia related kinase 0,0062066 0,3366906 114,4 273 0,419 1

Heterogeneou s nuclear ribonucleoprot ein U (scaffold attachment 0,0112518 0,3858197 78,9 188,1 0,419 factor A) zinc finger, AN1-type 0,0226746 0,460045 58,8 140,2 0,419 domain 1 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex- associated 0,0080558 0,3552023 98,4 235,6 0,418 protein aldehyde dehydrogenas e 2 family 0,0221793 0,4567432 573,8 1372,6 0,418 (mitochondrial) 0,0342502 0,4961507 83,3 199,2 0,418 ataxin 1 CDNA FLJ35556 fis, clone SPLEN200484 269 0,0001222 0,1541482 173,1 415,1 0,417 4 mitochondrial ribosomal 0,003445 0,3039332 150,6 361,3 0,417 protein L39 stress 70 protein chaperone, microsome- associated, 0,0149131 0,413266 198,8 477 0,417 60kDa mitogen- activated protein kinase kinase kinase 0,0453645 0,516644 96,1 230,3 0,417 2 0,0071862 0,3462686 225,9 543 0,416 KIAA1754 cytoskeleton- associated 0,0139329 0,4062323 598,6 1439,3 0,416 protein 4 cysteine-rich PDZ-binding 0,0205412 0,4485902 125,2 301,1 0,416 protein

neutrophil cytosolic factor 0,003966 0,3133541 160,2 385,7 0,415 4, 40kDa oxidized low density lipoprotein (lectin-like) 0,0096197 0,3693519 98,1 236,3 0,415 receptor 1 replication factor C (activator 1) 5, 0,0134732 0,4041641 36,8 88,7 0,415 36.5kDa asparagine- linked glycosylation 6 homolog (S. cerevisiae, alpha-1,3- glucosyltransfe 0,0145878 0,4106872 87,4 210,8 0,415 rase) 0,0150705 0,4143327 226,7 546,9 0,415 serglycin

MRNA; cDNA DKFZp762E13 14 (from clone DKFZp762E13 0,0184499 0,4377222 83,6 201,6 0,415 14) Homo sapiens, clone IMAGE:33529 0,0062009 0,3366906 56 135,2 0,414 13, mRNA myeloperoxida 0,0300013 0,4827695 28,5 68,8 0,414 se tryptase 0,0383821 0,5072367 38,5 92,9 0,414 alpha/beta 1 tripartite motif- 0,0016923 0,2418833 45,5 110,1 0,413 containing 13 CDNA FLJ13202 fis, clone NT2RP300450 0,0066276 0,3412079 45,4 109,8 0,413 3 cysteine-rich PDZ-binding 0,0308216 0,4870313 37 89,5 0,413 protein CDNA: FLJ21508 fis, clone 0,0206221 0,4485902 100,1 243 0,412 COL05723 period homolog 2 44 0,0009252 0,2205071 73,9 179,6 0,411 (Drosophila) Transcribed 0,0074348 0,3504479 30,4 73,9 0,411 locus zinc finger 139 0,0005181 0,1940962 50,6 123,3 0,41 protein 638 G protein- coupled receptor kinase 0,0247495 0,4667247 15,5 37,8 0,41 5 nuclear receptor subfamily 1, group D, 82 0,0008807 0,218874 71,6 174,9 0,409 member 2

jumonji, AT rich interactive 0,002982 0,290098 135,4 330,9 0,409 domain 2 Transcribed 0,0411414 0,5116636 27 66 0,409 locus

Full length insert cDNA 0,0469154 0,521044 30,4 74,3 0,409 clone YF47B02

Abelson helper integration site 191 0,0008756 0,2186001 40,7 99,8 0,408 1 arginine/serine- rich coiled-coil 0,0010399 0,2205294 58,8 144,2 0,408 1 chromosome 18 open reading frame 0,0023628 0,2714688 153 374,8 0,408 1 GTP-binding protein 10 212 0,0003904 0,1872379 56,9 139,9 0,407 (putative) mutS homolog 0,01267 0,3985801 57,5 141,3 0,407 6 (E. coli) phosphoinositi de-3-kinase, regulatory subunit 4, 0,002956 0,2896601 79,6 196,2 0,406 p150 hypothetical protein 0,0280942 0,4758739 52,7 129,8 0,406 LOC283551

elongation factor Tu GTP binding domain 0,0013897 0,238971 243,4 601,7 0,405 containing 1

cyclin- dependent kinase inhibitor 3 (CDK2- associated dual specificity 0,0158691 0,4196703 26,8 66,2 0,405 phosphatase) tetratricopeptid e repeat 0,0239287 0,4638862 18 44,4 0,405 domain 3

Tubulin tyrosine ligase- like family, 0,0457404 0,5177385 67 165,6 0,405 member 4 chromosome 21 open reading frame 207 0,0005532 0,1940962 64 158,4 0,404 45

chromosome 1 open reading 0,002408 0,2720759 29,5 73 0,404 frame 71 Transcribed 0,0216076 0,4524803 89,3 221,1 0,404 locus

chromosome X open reading 0,0045507 0,3197234 56 138,9 0,403 frame 15 protein arginine methyltransfer 0,0385543 0,5072367 38,6 95,9 0,403 ase 3 muscleblind- like 0,0017983 0,2490398 461,8 1147,9 0,402 (Drosophila)

chromosome 4 open reading 0,0115284 0,3885321 39 96,9 0,402 frame 30 ATPase, class 0,004575 0,3197234 102,1 254,7 0,401 V, type 10D CDNA: FLJ21881 fis, clone 0,0066528 0,3412212 31,8 79,4 0,401 HEP02746

chromosome 1 open reading 0,0012532 0,2302772 26,4 66 0,4 frame 109 short stature 0,0077109 0,3505421 10,8 27 0,4 homeobox 2 0,0089112 0,3635583 27,7 69,3 0,4 spastin

dual specificity 0,0165789 0,4254648 795,2 1988 0,4 phosphatase 6 phosphonofor mate immuno- associated 0,005203 0,3266062 44,4 111,2 0,399 protein 5 membrane- spanning 4- domains, subfamily A, 0,0349091 0,4971024 421 1054,4 0,399 member 7

transmembran 0,0384649 0,5072367 255,3 640 0,399 e protein 38B THUMP domain 68 0,0001748 0,1541482 72,9 183,1 0,398 containing 3

chromosome 5 open reading 0,0016347 0,2418041 185,1 465,4 0,398 frame 26 EF-hand domain (C- terminal) 0,0055104 0,3279506 45,9 115,3 0,398 containing 1

coiled-coil domain 0,00718 0,3462686 18 45,2 0,398 containing 147 synaptotagmin 0,0145735 0,4106872 64,3 161,7 0,398 XI ubiquitin specific 0,007093 0,3458012 65,2 164,6 0,396 peptidase 1

insulin receptor 0,0012174 0,2279498 76,7 194,2 0,395 substrate 2

eukaryotic translation initiation factor 0,0020595 0,2589333 53,3 135,1 0,395 4A, isoform 2 ankyrin repeat 55 0,0005435 0,1940962 101,3 257,3 0,394 domain 28 oxidation 0,0426234 0,5127624 64,4 164 0,393 resistance 1 carboxypeptida 0,0453591 0,516644 116,6 296,4 0,393 se D CDC28 protein kinase regulatory 0,0089522 0,3635583 252,1 643,3 0,392 subunit 1B zinc finger protein 36, C3H type-like 0,0052179 0,3267775 63,7 162,8 0,391 2 centromere 0,0083588 0,3576553 126,2 322,8 0,391 protein N nuclear receptor subfamily 4, group A, 0,0151386 0,4150968 26 66,5 0,391 member 2 family with sequence similarity 54, 0,0015106 0,2418041 23,6 60,5 0,39 member A Transcribed 0,0085066 0,3591295 24,5 62,9 0,39 locus dehydrogenas e/reductase (SDR family) 0,0283787 0,4768302 317,2 813,6 0,39 member 9

REV3-like, catalytic subunit of DNA polymerase 0,004679 0,3197234 87,7 225,5 0,389 zeta (yeast) Transcribed 0,0093646 0,3687888 117,5 302 0,389 locus gamma- glutamyl hydrolase (conjugase, folylpolygamm aglutamyl 0,0194286 0,4422393 91,3 234,7 0,389 hydrolase) heparin- binding EGF- like growth 0,0198171 0,4461705 168,3 432,8 0,389 factor Full length insert cDNA clone 152 0,0001303 0,1541482 46,5 120 0,388 YY61D04 cysteine-rich PDZ-binding 0,0407795 0,5112983 113,7 293,4 0,388 protein Transcribed 258 0,0005374 0,1940962 38,9 100,4 0,387 locus HtrA serine 0,0011322 0,2251019 110,1 284,3 0,387 peptidase 2 transmembran 0,0371234 0,5031712 56,5 146,5 0,386 e protein 48 crystallin, zeta (quinone reductase)-like 0,0113594 0,3858197 191,4 497 0,385 1 TATA element modulatory 0,0116497 0,3891601 87,5 227,2 0,385 factor 1

interferon regulatory factor 2 binding 197 0,000756 0,2088164 29,1 75,7 0,384 protein 2 epithelial membrane 0,0153305 0,4157714 590,9 1537,9 0,384 protein 1 Transcribed locus, moderately similar to NP_057696.2 mitochondrial solute carrier protein [Homo 0,035287 0,4980167 75,1 196,1 0,383 sapiens] RAD51 associated 0,018494 0,4377289 32,4 84,9 0,382 protein 1

polymerase (DNA 0,0316051 0,4889931 13,1 34,3 0,382 directed), theta kinetochore 0,0119881 0,3910796 29,9 78,5 0,381 associated 1 Transcribed 0,0134352 0,4041641 144,7 379,6 0,381 locus hypothetical 0,0019669 0,2562745 16,4 43,2 0,38 LOC339541 dehydrogenas e/reductase (SDR family) 0,0391471 0,5080329 282,3 743,8 0,38 member 9 sortilin-related receptor, L(DLR class) A repeats- 0,0491953 0,5246251 163,3 429,5 0,38 containing chromosome 14 open reading frame 120 8,20E-05 0,1541482 33,5 88,5 0,379 145

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 0,0220967 0,4559722 713,7 1885,1 0,379 1), member 1

CSRP2 0,0325315 0,4924549 71,9 189,5 0,379 binding protein TATA element modulatory 101 0,0004328 0,1940962 38,3 101,6 0,377 factor 1 chemokine (C- C motif) 0,0349742 0,4971024 1080,4 2868 0,377 receptor 1 hypothetical 0,0282065 0,4764258 66,2 176,2 0,376 LOC145853 family with sequence similarity 119, 0,0018734 0,2522861 51,6 137,7 0,375 member A hypothetical protein 0,0184564 0,4377222 45,7 121,8 0,375 LOC728177 transcription termination factor, RNA 172 4,31E-05 0,1541482 45,8 122,4 0,374 polymerase I dpy-19-like 3 0,0086984 0,3602917 34,4 92,1 0,374 (C. elegans) zinc finger protein 36, C3H type-like 0,0118461 0,3891601 351,5 939,9 0,374 2 Pellino homolog 1 0,0388338 0,5072367 1022,1 2730,5 0,374 (Drosophila) growth arrest- 0,0026191 0,2797591 327,4 876,6 0,373 specific 5

small nucleolar RNA host gene (non-protein 0,0096433 0,3696189 194,3 521,5 0,373 coding) 8 muscleblind- like 0,0166526 0,425997 96,2 257,9 0,373 (Drosophila)

SHC SH2- domain binding 108 0,0002374 0,16423 14,4 38,7 0,372 protein 1

histone cluster 146 0,0003539 0,1819093 15,8 42,5 0,372 1, H2bg

REV3-like, catalytic subunit of DNA polymerase 0,0077832 0,3510054 48,2 129,6 0,372 zeta (yeast) ankyrin repeat 272 6,89E-05 0,1541482 30,9 83,6 0,37 domain 28

methyl-CpG binding domain 0,0016847 0,2418041 153,5 414,6 0,37 protein 4 CDNA FLJ13601 fis, clone PLACE101006 0,0228149 0,4610454 25,4 68,7 0,37 9 Pellino homolog 1 0,0479426 0,521854 859,1 2321,4 0,37 (Drosophila) UTP15, U3 small nucleolar ribonucleoprot ein, homolog 97 0,0004948 0,1940962 23,4 63,5 0,369 (S. cerevisiae)

nascent polypeptide- associated complex alpha subunit /// nascent- polypeptide- associated complex alpha polypeptide pseudogene 1 /// NACA family member 3 0,0059705 0,331305 48,8 132,1 0,369 pseudogene

dual specificity 0,0167721 0,4260897 511,1 1385,1 0,369 phosphatase 6 CD44 molecule (Indian blood 0,0214633 0,4522939 103,2 279,4 0,369 group) tubulin, gamma complex associated 0,0274565 0,4727831 57,7 156,5 0,369 protein 4

tRNA methyltransfer ase 6 homolog 136 0,000651 0,1999631 58,1 157,8 0,368 (S. cerevisiae) poly (ADP- ribose) polymerase family, member 69 0,0001613 0,1541482 44,5 121,1 0,367 2 MS4A13 0,0023209 0,2709605 113,1 309,1 0,366 protein CDK5 regulatory subunit associated 0,003569 0,3039862 137,1 375,1 0,366 protein 2 structural maintenance of chromosomes 0,0014744 0,2418041 124,5 340,9 0,365 4 acid phosphatase, 0,0015613 0,2418041 176,5 485,7 0,363 prostate H3 histone, family 3B 0,0020067 0,2571646 190,9 525,3 0,363 (H3.3B) FYVE, RhoGEF and PH domain 186 7,92E-05 0,1541482 65,5 180,9 0,362 containing 3 MRNA; cDNA DKFZp686E18 224 (from clone DKFZp686E18 0,0014023 0,2403472 23,1 63,9 0,362 224) epithelial membrane 0,0210515 0,4498978 365,6 1009,4 0,362 protein 1 integrin beta 3 binding protein (beta3- 0,00158 0,2418041 81,1 225,3 0,36 endonexin) Transcribed 0,0359112 0,4990053 58,1 161,5 0,36 locus trophoblast- derived noncoding 0,0072143 0,3465358 293,9 817,6 0,359 RNA solute carrier family 1 (glial high affinity glutamate transporter), 0,0347694 0,4971024 48 133,8 0,359 member 3 myotubularin related protein 0,0019265 0,2550397 69,2 193,5 0,358 11 chromosome 21 open reading frame 166 0,0003691 0,1824597 59,1 165,4 0,357 66 chromosome 12 open reading frame 0,0049121 0,3216637 164,6 461,2 0,357 57 CDNA: FLJ21452 fis, clone 0,005424 0,3274124 60,6 169,8 0,357 COL04505

Splicing factor, arginine/serine- 0,0022821 0,270659 21,1 59,2 0,356 rich 11 0,0047582 0,3199091 77,5 217,5 0,356 ADAM-like, 0,0081385 0,3562602 33,9 95,3 0,356 decysin 1 splicing factor, arginine/serine- 169 0,0001707 0,1541482 85 240,1 0,354 rich 18 Zwilch, kinetochore associated, homolog 0,0020744 0,2599502 56,9 160,8 0,354 (Drosophila) ORM1-like 1 0,0314534 0,488547 39,3 111 0,354 (S. cerevisiae) THAP domain 10 5,30E-05 0,1541482 81 229,5 0,353 containing 11

insulin receptor 145 0,0003619 0,1824597 150,6 427,2 0,353 substrate 2 retinoic acid 0,0034283 0,3039332 95 268,8 0,353 induced 1 growth arrest- 0,0029019 0,2890007 429,3 1219,2 0,352 specific 5 chromosome 14 open reading frame 0,0018062 0,2490398 28,8 82,1 0,351 102 bromodomain 0,0173847 0,4305249 101,7 290 0,351 containing 8

interferon regulatory factor 2 binding 0,0016994 0,2419654 348,2 994,3 0,35 protein 2

guanylate binding protein 1, interferon- inducible, 0,0476903 0,521195 206 588,8 0,35 67kDa replication factor C (activator 1) 4, 0,0193316 0,4417307 35,2 101,1 0,348 37kDa Cbp/p300- interacting transactivator, with Glu/Asp- rich carboxy- terminal 151 0,0001469 0,1541482 234,3 675,2 0,347 domain, 2 Transcribed 0,015517 0,4179271 10,8 31,1 0,347 locus heparin- binding EGF- like growth 0,0210115 0,4498978 207,6 597,5 0,347 factor heat shock 70kDa protein 0,0259637 0,4702698 153,8 442,9 0,347 6 (HSP70B') G protein- coupled 0,0446519 0,5153797 12,2 35,2 0,347 receptor 171 0,0012365 0,2288038 139,2 403,1 0,345

excision repair cross- complementing rodent repair deficiency, complementati 0,0268527 0,4727831 31,8 92,1 0,345 on group 8 dihydrolipoami de dehydrogenas 0,0012027 0,227535 166,2 482,6 0,344 e oxidation 0,0032893 0,3012437 44,8 130,4 0,344 resistance 1

interleukin 1 family, member 0,0086857 0,3602917 24 69,8 0,344 8 (eta) thioredoxin interacting 0,0384226 0,5072367 255,6 746,1 0,343 protein ELK3, ETS- domain protein (SRF accessory 0,0062748 0,3373399 50,3 147 0,342 protein 2)

Full-length cDNA clone CS0DI009YA1 4 of Placenta Cot 25- normalized of Homo sapiens 0,0014631 0,2418041 23,1 67,7 0,341 (human)

MAD2 mitotic arrest deficient- 51 0,0006906 0,2063309 27,5 81,2 0,339 like 1 (yeast) insulin-like growth factor binding protein 0,0155699 0,4179451 73,2 216,2 0,339 6 zinc finger protein 36, C3H type-like 208 0,0005256 0,1940962 51,9 154 0,337 2

MAD2 mitotic arrest deficient- 109 0,0002372 0,16423 23,3 69,6 0,335 like 1 (yeast) DEAH (Asp- Glu-Ala-His) box 0,003647 0,3077156 52,1 155,3 0,335 polypeptide 9 0,0239304 0,4638862 22,5 67,1 0,335 vanin 1

interferon regulatory factor 2 binding 104 0,0003156 0,1742973 65,5 195,9 0,334 protein 2 chromosome 12 open reading frame 0,0034287 0,3039332 36,2 108,5 0,334 47

MRNA; cDNA DKFZp547O02 10 (from clone DKFZp547O02 0,0074726 0,3505421 18 53,9 0,334 10) TSC22 domain family, member 0,0135713 0,4041641 126,7 379,7 0,334 3 ring finger protein (C3H2C3 type) 0,0319095 0,4894884 38,8 116,1 0,334 6 GATA binding 38 3,19E-05 0,1541482 37,3 112,1 0,333 protein 2

primase, DNA, polypeptide 1 0,0018465 0,2504655 32 96,2 0,333 (49kDa) structural maintenance of chromosomes 0,0021783 0,2646635 30,5 91,5 0,333 3 Transcribed 270 0,0001212 0,1541482 67 202,6 0,331 locus

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 0,0198244 0,4461705 613,2 1850,9 0,331 1), member 1 mitochondrial translational release factor 249 0,0007997 0,2092038 36,1 109,3 0,33 1

ATPase family, AAA domain 0,00389 0,3127732 27,6 84,2 0,328 containing 2 Rac GTPase activating 0,0010317 0,2205294 34,5 105,5 0,327 protein 1 SEC31 homolog A (S. 224 0,0001748 0,1541482 79,4 244,8 0,324 cerevisiae) CDNA FLJ41270 fis, clone BRAMY20363 60 0,0004418 0,1940962 58,2 179,4 0,324 87 CDNA FLJ33091 fis, clone TRACH200066 262 0,0004836 0,1940962 49,5 153 0,324 0

NMDA receptor 0,0010777 0,2213833 43,8 135,2 0,324 regulated 1-like

spleen tyrosine 0,0203244 0,4485902 178,1 551,7 0,323 kinase transducer of 230 8,24E-05 0,1541482 86,3 267,6 0,322 ERBB2, 1 THUMP domain 250 0,0007016 0,2073512 20,8 64,8 0,321 containing 3 CDNA FLJ13202 fis, clone NT2RP300450 0,0168016 0,4260897 19,7 61,4 0,321 3 Rap guanine nucleotide exchange 0,0057968 0,3304939 41,5 130,2 0,319 factor (GEF) 6 matrix metallopeptida se 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV 0,0076969 0,3505421 122,8 384,7 0,319 collagenase)

multiple EGF- 0,0127542 0,4003076 89,2 280,6 0,318 like-domains 9 ras homolog gene family, 36 5,88E-05 0,1541482 196,5 619,1 0,317 member B minichromoso me maintenance complex 0,0044885 0,3197234 17,9 56,9 0,315 component 8 epithelial membrane 0,0032037 0,2999829 12,9 41,8 0,309 protein 1 collectin sub- family member 0,0149365 0,4137047 108,7 352,7 0,308 12 ankyrin repeat 0,0075784 0,3505421 115 374,5 0,307 domain 22 V-set and immunoglobuli n domain 0,0096935 0,3696189 44,2 144,3 0,306 containing 4 Rho guanine nucleotide exchange 0,021729 0,4524803 55,1 181,3 0,304 factor (GEF) 7 thrombomoduli 0,0059036 0,3307111 81,3 268,2 0,303 n regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing 0,0085381 0,3593692 112,2 372,1 0,302 protein 2 ankyrin repeat 0,0348905 0,4971024 178,8 594,9 0,301 domain 22 cathelicidin antimicrobial 0,012202 0,3928661 120,3 401,5 0,3 peptide endothelial differentiation, sphingolipid G- protein- coupled 141 0,0004684 0,1940962 59,1 198,2 0,298 receptor, 3 nucleoporin 0,0046717 0,3197234 33,4 111,9 0,298 35kDa chromosome 13 open reading frame 216 0,0003139 0,1742973 1746,6 5877,9 0,297 15

MRNA; cDNA DKFZp666E11 8 (from clone DKFZp666E11 0,0212413 0,4513673 61 205,5 0,297 8) TTK protein 201 0,0007061 0,2075592 11,1 37,5 0,296 kinase G protein- coupled 0,003227 0,2999829 180,6 613,2 0,295 receptor 84 0,0457094 0,5177385 1797,5 6108,4 0,294 interleukin 8 0,0094769 0,3688312 119,1 408,4 0,292 claudin 23 structural maintenance of chromosomes 0,0104263 0,3766691 46,6 160,7 0,29 2 membrane- spanning 4- domains, subfamily A, member 3 (hematopoietic 0,0369363 0,5021114 13,1 45,2 0,29 cell-specific) chromosome 21 open reading frame 234 2,21E-05 0,1541482 120,3 416,5 0,289 66

tumor necrosis factor (ligand) superfamily, 0,0292354 0,4812171 107,4 371,1 0,289 member 14

cyclin- dependent kinase inhibitor 3 (CDK2- associated dual specificity 0,0056906 0,3299401 15,8 54,9 0,288 phosphatase)

tyrosine kinase with immunoglobuli n-like and EGF- 0,0024924 0,2756013 124,8 439,5 0,284 like domains 1 BUB1 budding uninhibited by benzimidazole s 1 homolog 273 2,52E-05 0,1541482 11,6 41,5 0,28 (yeast) chromosome 21 open reading frame 219 0,0002685 0,1708912 35 126 0,278 45 pyruvate dehydrogenas e kinase, 167 0,0003062 0,1742973 19,8 71,1 0,278 isozyme 4 similar to Complement 0,0024625 0,274856 185,4 666 0,278 C3 precursor

histidine 123 4,50E-06 0,115911 34,7 127,1 0,273 decarboxylase proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major 0,0069391 0,3458012 74,2 272,4 0,272 basic protein) G protein- coupled 13 0,0010057 0,2205294 628,4 2316,3 0,271 receptor 109B high-mobility 0,0047634 0,3199091 64,9 240,7 0,27 group box 2 coiled-coil domain 159 0,000808 0,2103686 36,4 137,5 0,265 containing 14 CDK5 regulatory subunit associated 0,0022176 0,2672586 86,6 326,7 0,265 protein 2 G protein- coupled 0,0029468 0,2896601 96,7 364,3 0,265 receptor 65

NLR family, CARD domain 0,0450051 0,516331 47,7 180 0,265 containing 4

tubulin tyrosine ligase-like family, member 0,0157917 0,4196703 129,5 491,5 0,263 4 solute carrier family 12 (potassium/chl oride transporters), 121 7,77E-05 0,1541482 33,4 131,3 0,254 member 8 breast cancer 0,0070488 0,3458012 86,2 340,6 0,253 2, early onset chromosome 11 open reading frame 0,0112662 0,3858197 69,5 275,2 0,253 32 lysozyme (renal 0,0384664 0,5072367 777,1 3145,1 0,247 amyloidosis) development and differentiation enhancing 0,0010599 0,2205294 97,8 398,8 0,245 factor 2 Transcribed 0,0070038 0,3458012 37,2 152,7 0,244 locus synaptotagmin 6 0,0002142 0,1623024 34,7 145,7 0,238 XI nucleolar and spindle associated 0,0069404 0,3458012 35,3 151,7 0,233 protein 1

MRNA; cDNA DKFZp762E13 14 (from clone DKFZp762E13 0,0235046 0,4632294 45,1 193,4 0,233 14) Fc fragment of IgE, high affinity I, receptor for; alpha 0,010494 0,3766691 59,5 274,1 0,217 polypeptide myotubularin related protein 0,0016192 0,2418041 43,2 199,8 0,216 11 chemokine (C- C motif) ligand 0,0141401 0,4077584 427,2 2030,6 0,21 7

shugoshin-like 237 6,50E-06 0,115911 15 72,2 0,208 2 (S. pombe)

progestin and adipoQ receptor family 0,0067491 0,3434229 28,2 135,6 0,208 member V

MRNA; cDNA DKFZp586F22 24 (from clone DKFZp586F22 73 3,95E-05 0,1541482 23,5 114,8 0,205 24) 171 0,0001339 0,1541482 103,5 509,1 0,203 cystatin E/M ankyrin repeat 0,0011971 0,227535 44,5 219,8 0,202 domain 28 solute carrier family 16, member 6 (monocarboxyli c acid 113 0,0001829 0,1562509 30,3 150,7 0,201 transporter 7) HOP 91 0,0007512 0,2088164 163,2 820,3 0,199 homeobox solute carrier family 11 (proton- coupled divalent metal ion transporters), 164 0,0005749 0,1948388 58,9 303,8 0,194 member 1 breast cancer 28 0,0002811 0,1742973 29,2 161,3 0,181 2, early onset dihydropyrimidi 0,0015895 0,2418041 65,8 389,2 0,169 nase-like 3 hemoglobin, 0,0013248 0,2367106 28,9 180,7 0,16 delta C-type lectin domain family 15 0,0009959 0,2205294 40,8 256,8 0,159 12, member A

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 0,0036456 0,3077156 25,6 164 0,156 1), member 1 C-type lectin domain family 0,0182856 0,4364168 12,7 82,4 0,154 5, member A CDNA FLJ13464 fis, clone PLACE100347 0,0041479 0,3163535 18,1 132 0,137 8 dihydropyrimidi 0,0028834 0,288618 53,1 390,1 0,136 nase-like 3 carboxypeptida se A3 (mast 184 0,0003058 0,1742973 25 188,2 0,133 cell)

serpin peptidase inhibitor, clade B (ovalbumin), 0,0129892 0,401446 135,2 1245 0,109 member 2

triggering receptor expressed on 0,0015217 0,2418041 79,5 781,9 0,102 myeloid cells 1 0,0021977 0,2664285 477 4720,6 0,101 mucin-like 1 solute carrier family 16, member 6 (monocarboxyli c acid 72 6,15E-05 0,1541482 29 288,6 0,1 transporter 7) serine peptidase inhibitor, Kazal 196 0,0007678 0,2088164 53,8 665,9 0,081 type 1 hemoglobin, 0,0256461 0,4702698 44,3 604,1 0,073 beta hemoglobin, 0,0197848 0,4458817 58,2 843,8 0,069 beta S100 calcium binding protein 0,0022639 0,2690842 152,7 3076,8 0,05 A8

70 0,0001532 0,1541482 80,1 2160,6 0,037 CD14 molecule