Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000301935Cyc: Acinetobacter baumannii AB_2008-15-52 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari a metal (2-aminoethyl) 1-(β-D phosphate cation ammonium phosphate phosphonate acetate ribofuranosyl) ammonium ammonium ethanolamine benzoate nicotinamide predicted predicted ABC ABC transporter of RS0104915 RS0112790 RS0102580 RS0107275 Eat RS0104750 transporter (2-aminoethyl) RS0110545 ActP of phosphate phosphonate

1-(β-D ammonium phosphate ribofuranosyl) ammonium ammonium ethanolamine benzoate acetate a metal nicotinamide (2-aminoethyl) phosphate phosphonate cation

Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Detoxification a DNA containing L-alanyl-γ-D- L-alanyl-γ-D- a ribonucleoside a uracil 1498 (3R,5S)-3- Aminoacyl-tRNA Charging a purine UDP-N-acetyl- a [glutamine- a ribonucleoside L(or D)-O- [2Fe-2S] iron-sulfur cluster biosynthesis TCA cycle superpathway of glyoxylate bypass and TCA an apurinic/ UDP-N-acetyl- glutamyl-meso-2,6- glutamyl-meso- 2',3'-cyclic in 16S rRNA hydroxy-1- met flavin biosynthesis I (bacteria and plants) superpathway of tetrahydrofolate biosynthesis superpathay of heme b ubiquinol-8 biosynthesis (prokaryotic) superpathway of adenosylcobalamin salvage from cobinamide I pyrroloquinoline bis(guanylyl molybdenum ribonucleoside adenosylcobinamide α-D-muramate synthetase]- ATP 5'-monophosphate phosphoserine ITP reactive oxygen species degradation apyrimidinic site α-D-muramate diaminopimeloyl- diaminopimelate phosphate phosphoserine 16S rRNA pyrroline-5- biosynthesis from glutamate pyridoxal 5'-phosphate biosynthesis I cofactor) biosynthesis bifunctional DNA- UDP-N- L-tyrosine multifunctional tRNA bifunctional bifunctional all-trans- quinone biosynthesis tRNA charging arsenate 5'-triphosphate bifunctional UDP-N-D-alanine bifunctional [glutamate- non-canonical purine (uracil(1498)-N(3))- carboxylatepyrroline-5- acetyl-CoA androstenedione degradation Fatty Acid and Lipid Degradation acetylmuramate:L- nucleotidyltransferase/ metallophosphatase/ phosphatase glutamate N- L-cysteine desulfurase cob(II)inamide MoO - gln detoxification formamidopyrimidine -ammonia ligase]- NTP pyrophosphatase, 4-hydroxybenzoate octaprenyl 2 glutaminyl-tRNA biosynthesis via transamidation adenosylcobinamide acetylmuramate:L- methyltransferase: carboxylate D-erythrose superoxide alanyl-gamma-D- 2',3'-cyclic 5'-nucleotidase: SerB: serB acetyltransferase/ GTP GTP glu a PqqA peptide SAM molybdopterin II (glutaredoxin) kinase/ glycosylase/ alanyl-gamma-D- adenylyl-L-tyrosine RdgB/HAM1 family: rdgB B753_RS0108390 4-hydroxybenzoatediphosphate 4-phosphate arginine-- glutamyl- meso- B753_RS0118870 reductase: amino-acid cysteine ATP:cob(I)alamin γ cofactor bis(molybdenum arg androst-4-ene-3,17-dione DNA-(apurinic or phosphorylase/ phosphodiesterase/ bifunctional octaprenyltransferase: glutamate C tRNA ligase: oxaloacetate superoxide dismutase: arsenate adenosylcobinamide- glutamyl- meso- diaminopimelate nucleoside triphosphate 16S rRNA B753_RS0103345 acetyltransferase desulfurase: adenosyltransferase: 3 apyrimidinic site) lyase: 2' nucleotidase/ 5'-nucleotidase phosphoserine bifunctional GTP -tyrosine C cofactor) synthase: B753_RS0112945 glu B753_RS0117135 arsenate reductase: phosphate diaminopimelate [glutamate-- pyrophosphohydrolase: 3-octaprenyl-4-ubiA an L-arginyl- ligase: mpl 2'phosphatase: SurE: phosphatase/ (uracil(1498)-N(3))- pyrroline-5- ArgJ: argJ B753_RS0108530 cyclohydrolase an L-glutamyl- B753_RS0115820 ligase: pqqE B753_RS0114045 B753_RS0116045 UDP-N-acetylmuramoyl-ligase: mpl UDP-N-acetyl- ammonia-ligase] B753_RS0103490 3,4-dihydroxy- a PqqA peptide with bis(molybdenum [tRNA Arg ] B753_RS0108235 guanylyltransferase: methyltransferase: carboxylate Glu hydroxybenzoate [corrinoid type II citrate synthase: gltA γ α B753_RS0117120 B753_RS0101640 homoserine amino-acid N- I FolE: folE Arg hydrogen peroxide endonuclease L-alanyl- -D- -D-muramoyl- adenylyltransferase: an S-sulfanyl-[L- 2-butanone- [tRNA ] linked Glu-Tyr residues 4-phospho- cofactor) a tRNA arsenate reductase a purine B753_RS0118320adenosyl- a ribonucleoside IMP B753_RS0117105 reductase: 7,8- adenosyltranferase]- glutamyl-meso-2,6- L-alanyl-γ-D- a [glutamine a ribonucleoside phosphotransferase an N 3 - acetyltransferase: cysteine desulfurase] 4-phosphate D-erythronate malate:quinone (glutaredoxin): arsC III: nth B753_RS0115670 glutamyl-tRNA cob(II)inamide molybdenum cofactor androsta-1,4-diene-3,17-dione ribonucleoside cobinamide a 3'-terminal a 5'-phospho- 3'-phosphate ThrH: 1498 B753_RS0110415 dihydroneopterin oxidoreductase: mqo diaminopimeloyl- glutamyl-meso-2,6- synthetase]-O methyluracil B753_RS0110915 synthase/GTP reductase: erythronate- guanylyltransferase: arsenite 5'-diphosphate phosphate Hyp 3'-triphosphate an L-glutamyl- catalase: unsaturated sugar [DNA] D-alanine diaminopimelate 4 -(5'-adenylyl) B753_RS0102425 N-acetyl-L- cyclohydrolase 4-phosphate malate dehydrogenase: in 16S rRNA thr thr B753_RS0108770 2-octaprenylphenol B753_RS0114045 [tRNA Gln ] gln B753_RS0113155 -L-tyrosine methionine RS0113585 II: ribB 2-amino-4-[5-(2-amino- dehydrogenase: bis(guanylyl B753_RS0117375 serine serine serine an S-sulfanyl-[cysteine (S)-4-amino-5- [corrinoid cysteine-- [+ 2 isozymes] 2-carboxylatoethyl)-2- B753_RS0106065 molybdopterin) cys Asp-tRNA(Asn) H O hydroxyl radical GTP oxopentanoate 2-octaprenylphenol carbamoyl- 9α-hydroxyandrosta- 2 desulfurase]-[disordered- 7,8- adenosyltranferase]- tRNA ligase: /Glu-tRNA(Gln) cyclohydrolase hydroxylase: hydroxyphenyl]pentanedioate (3R)-3-hydroxy-2-oxo- cofactor phosphate synthase: (S)-malate citrate 1,4-diene-3,17-dione form scaffold dihydroneopterin glutamate-1- cob(I)inamide B753_RS0110360 an L-cysteinyl- amidotransferase: O arsenite II: ribA B753_RS0112325 4 phosphooxybutanoate B753_RS0100945 2 a [glutamine guanosine 2445 4-methyl-3- citrate RS0104585 citrate protein] complex semialdehyde ATP:cob(I)alamin [tRNA Cys ] aconitate hydratase phosphoenol an [HPr]- a guanine (S)-1-pyrroline- 2,5-diamino-6- 3'-phosphate 3-(all-trans gatB methylmalonate semialdehyde aci-nitroethane methyl red synthetase]-O 2',3'-cyclic a uridine in tRNA cyclic-AMP oxoadipate- 2,1- adenosyltransferase: 3-phosphoserine/ a tRNA Cys carB AcnA: acnA pyruvate L-histidine in 23S rRNA L-ornithine 5-carboxylate (5-phospho-D- B753_RS0102380 4 -octaprenyl) 2-amino-4-[3-(2-amino-2- [+ 9 isozymes] methylmalonate- phosphoenolpyruvate- nitronate FMN-dependent -(5'-adenylyl) monophosphate tRNA-dihydrouridine bifunctional 3',5'-cyclic-AMP trifunctional enol-lactone aminomutase: B753_RS0115820 phosphohydroxythreonine a 5-phosphooxy- bifunctional aconitate 3-hydroxy-9,10- multifunctional tRNA arginine N- 3-oxoadipate ribosylamino) benzene-1,2-diol carboxylatoethyl)-6-oxocyclohexa- semialdehyde protein monooxygenase: NADH- -L-tyrosine bifunctional [glutamate- synthase C: phosphodiesterase: transcriptional hemL aminotransferase: L-glutamyl- hydratase 2/2- secoandrosta-1,3,5(10) nucleotidyltransferase/ 23S rRNA succinyltransferase: formate RS0100300 formate a [cysteine desulfurase]- pyrimidin- bifunctional 3- 1,4-dien-1-yl]pentanedioate ammonium malate synthase G: dehydrogenase (CoA B753_RS0101385 azoreductase: -ammonia ligase]- B753_RS0108990 B753_RS0107415 regulator/proline enol- 7,8- adenosylcobinamide B753_RS0105960 Gln class II fumarate phosphotransferase (guanine(2069)-N(7) nitrite nitrite S-sulfanyl-[disordered- 4(3H)-one demethylubiquinone 3- [tRNA ] methylisocitrate -triene-9,17-dione 2',3'-cyclic B753_RS0107010 lactonase: dihydroneopterin 5-aminolevulinate hydratase: fumC B753_RS0113370 acylating): mmsA PtsP: B753_RS0112030 nitronate B753_RS0101310 adenylyl-L-tyrosine tRNA dihydrouridine )-methyltransferase 3',5'-cyclic-nucleotide dehydrogenase/L- diaminohydroxyphosphoribosylaminopyrimidine 4-phosphooxy- glutamine--tRNA dehydratase: phosphodiesterase/ arginine N- pcaD form scaffold O-methyltransferase/2- bifunctional D-glyceraldehyde monooxygenase: phosphorylase/ synthase DusB: RlmK/23S rRNA phosphodiesterase: glutamate gamma- dihydroneopterin pyruvate L-threonine ligase/YqeY domain Asp-tRNA(Asn) Hormone Biosynthesis fumarate hydratase: B753_RS0103095 methylmalonate- phosphoenolpyruvate- FMN-dependent 2' nucleotidase/ protein] complex deaminase: B753_RS0118570 porphobilinogen octaprenyl-6-hydroxy adenosylcobinamide 3-phosphate gln [glutamate-- B753_RS0100835 succinyltransferase: semialdehyde 3-oxoadipate D-ribulose 6-(2-amino-2-carboxylatoethyl) fusion protein: /Glu-tRNA(Gln) B753_RS0111665 semialdehyde -protein B753_RS0105515 NADH- 2'phosphatase: B753_RS0105520 (guanine(2445)-N(2) sulfate RS0117630 sulfate cysteine bifunctional aldolase: folB synthase: phenol methylase: kinase/ 4-hydroxythreonine- [unspecified a 5,6-dihydrouridine astA enol- 5-phosphate -1,2,3,4-tetrahydroquinoline- 1-deoxy-D-xylulose- 3,4-dihydroxy-9,10- dehydrogenase (CoA phosphotransferase: ptsP azoreductase: ammonia-ligase] )-methyltransferase N 2 -succinyl- dehydrogenase: desulfurase: B753_RS0110940 4-phosphate B753_RS0108040 an L-glutaminyl- amidotransferase: indole-3-acetate fumarate cis-aconitate degradation nitrite acetaldehyde B753_RS0117120 diaminohydroxyphosphoribosylaminopyrimidine 6-(hydroxymethyl) B753_RS0105160 adenosylcobinamide- 5-phosphate secoandrosta-1,3,5(10) Carboxylate Degradation an [HPr protein]- adenylyltransferase: in tRNA RlmL: AMP putA lactonase: B753_RS0108530 bifunctional 2,4-dicarboxylate Gln gatB biosynthesis aconitate hydratase acylating): mmsA π B753_RS0118635 L-ornithine deaminase/5-amino-6-(5-phosphoribosylamino) -7,8-dihydropterin 2-methoxy- phosphate dehydrogenase [tRNA ] -triene-9,17-dione N -phospho- pyruvate products] N,N-dimethyl-1,4- B753_RS0115670 3'-GMP pcaD an S-sulfanyl-[cysteine chorismate synthase: Gln fumarate reductase/ + B753_RS0115195 porphobilinogen B753_RS0102380 H NADH hydrogencarbonate propanoyl-CoA anthranilate a [glutamine- 2 4-methyl-3- 3,4-dihydroxy- uracil reductase RibD: ribD 6-(all-trans- guanylyltransferase: PdxA: pdxA a tRNA IV (bacteria) acetyl-CoA glyoxylate AcnA: acnA L-histidine an N - glu desulfurase]-S- 2-amino-4-hydroxy-6- B753_RS0106870 succinate dehydrogenase pyruvate fermentation phenylenediamine ADP synthetase]- oxoadipate sulfate RS0117525 sulfate 2-butanone- 5-amino-6-(5- octaprenyl)phenol 3-amino-1- (indole-3-yl) bifunctional aconitate superpathway of acetate methylguanine 2445 sulfanyl-[disordered- hydroxymethyldihydropteridine hydroxymethylbilane B753_RS0118320 flavoprotein subunit: to acetate IV L-tyrosine 4-phosphate phospho-D- 2-octaprenyl-6- 6-(2-amino-2-carboxylatoethyl) 1-deoxy-D-xylulose hydroxyacetone an L-glutaminyl- acetonitrile hydratase 2/2- form scaffold diphosphokinase: folK synthase: B753_RS0118650 utilization and formation in 23S rRNA adenosyl-cobinamide 5-phosphate Gln (1E,2Z)-3-hydroxy- synthase/GTP ribosylamino)uracil methoxyphenyl -7-hydroxy-8-oxo-1,2,3,4,7,8- 1-phosphate [tRNA ] methylisocitrate pyruvate protein] complex bifunctional 2-amino-4-hydroxy-6- 4-amino-4- B753_RS0107475 phosphate succinate 5,9,17-trioxo-4,5:9,10- predicted cyclohydrolase hydroxylase: hexahydroquinoline- thiamine formation from (indol-3-yl) dehydratase: acetate all trans-decaprenyl- hydroxymethyldihydropteridine dehydrogenase: sdhC disecoandrosta-1 acetate--CoA undecaprenyl- sn-glycero-3- DNA combined adenosine a guanine 2069 II: ribB diaminohydroxyphosphoribosylaminopyrimidine deoxychorismate preuroporphyrinogen B753_RS0101945 2,4-dicarboxylate pyridoxine 5'- glu acetamide B753_RS0103095 glycerophosphoserine DMKH DNA with lesion an L-glutamyl- an aldehyde butan-1-ol ABC bifunctional pyrithiamine and oxythiamine (yeast) isocitrate lyase: 2-methoxy-6- 2',3'-cyclic 2 sulfate sulfate 2-methoxy-6-all ligase: acs diphospho-N- with exogenous in 23S rRNA Gln deaminase/5-amino-6-(5-phosphoribosylamino) pyrophosphokinase: phosphate B753_RS0102785 sdhB (10),2-dien-4-oate acetate kinase: phosphoethanolamine [tRNA ] transporter 3,4- aminodeoxychorismate trans-octaprenyl- adenosylcobinamide 5,6-dimethylbenzimidazole an L-glutamyl- amidase: B753_RS0104570 acetylmuramoyl- UDP-N-acetyl- glycerophosphodiester 1,4-benzoquinol glycerophosphodiester DNA to form a monophosphate bifunctional bifunctional excinuclease NAD(P)- NAD(P)- a [cysteine uracil reductase RibD: ribD B753_RS0103160 uroporphyrinogen- synthase: succinate D-threo-isocitrate bifunctional multifunctional tRNA Asp-tRNA(Asn) of sulfate lyase: pabC kinase/ pyrithiamine Glu B753_RS0111655 ABC subunit UvrA: dihydroxy-2- 5-amino-6-(5- (7,8-dihydropterin- 1,4-benzoquinol [tRNA ] B753_RS0104000 NADP-dependent L-alanyl-γ-D- α-D-glucosamine phosphodiesterase: demethylmenaquinone phosphodiesterase: recombinational demethylmenaquinone 23S rRNA /Glu-tRNA(Gln) dependent alcohol dependent alcohol desulfurase]-(S- III synthase: nicotinate-nucleotide-- B753_RS0105625 glu crossover junction nucleotidyltransferase/ butanone-4- bifunctional adenosylcobinamide- 6-(2-amino-2-carboxyethyl) a tRNA isocitrate dehydrogenase: acetyl-CoA formate glutamyl-L-lysyl- undecaprenyldiphospho- B753_RS0115815 B753_RS0115815 junction methyltransferase/2- (guanine(2069)-N(7) B753_RS0117970 dehydrogenase: dehydrogenase: sulfanyl) -[disordered- phospho-D- 6-yl)methyl 4-aminobenzoate B753_RS0107480 dimethylbenzimidazole succinate methyltransferase/2- endodeoxyribonuclease 2',3'-cyclic amidotransferase: sulfate RS0101335 sulfate 2 phosphate thiaminase (indol-3-yl)acetate acetyl phosphate acetyl-CoA muramoylpentapeptide beta-N- phosphate ribitylamino)uracil diphosphate demethylmenaquinone -7,8-dioxo-1,2,3,4,7,8- B753_RS0101410 3-[(3aS,4S,7aS)-7a-methyl- D-alanyl-D-alanine glycerophosphoryl methoxy-6-polyprenyl-1,4- glycerophosphoryl methoxy-6-polyprenyl-1,4- )-methyltransferase excinuclease gatB B753_RS0100245 B753_RS0111315 form scaffold phosphoribosyltransferase: II: tenA succinyl-CoA ligase subunit (2Z,4Z)-2-hydroxyhexa- ditrans,octacis- RuvC: B753_RS0113725 phosphodiesterase/ synthase: uroporphyrinogen-III methyltransferase/2- guanylyltransferase: hexahydroquinoline pyridoxine 5'-phosphate 1,5-dioxo-octahydro-1H phosphate acetylglucosaminyltransferase: benzoquinol methylase RlmK/23S rRNA ABC subunit UvrB: protein] complex cobT beta: B753_RS0102810 NADP-dependent 2,4-dienoate undecaprenyldiphospho- diester benzoquinol methylase diester Holliday junction 2' nucleotidase/ B753_RS0102380 NAD(P)- NAD(P)- ribB acyl carrier B753_RS0118320 2,4-dicarboxylate 4-amino-2-methyl-5- -inden-4-yl]propanoate acetyltransferase: murG UbiE: B753_RS0112315 (guanine(2445)-N(2) B753_RS0105570 an L-glutaminyl- methoxy-6-polyprenyl-1,4- oxythiamine isocitrate dehydrogenase: N-acetyl-(N-acetyl-β-D- phosphodiesterase: 6-methoxy-3-methyl-UbiE: B753_RS0112315 phosphodiesterase: resolvase RuvX: 2'phosphatase: dependent alcohol dependent alcohol protein activation uroporphyrinogen pyrroloquinoline- B753_RS0111660 resolution of DNA without [tRNA Gln ] 1-deoxy-L- benzoquinol methylase adenosylcobinamide- α-ribazole 5'-phosphate pyridoxine/ pyrimidinemethanol isoleucine-- B753_RS0101400 acyl-CoA phosphate UDP B753_RS0106215 B753_RS0106215 MQH )-methyltransferase dehydrogenase: dehydrogenase: sulfite RS0111285 sulfite decarboxylase: ile D-gluconate glucosaminyl)muramoyl- 2-all-trans-decaprenyl- recombinationalB753_RS0112480 B753_RS0117120 2 glycero-tetrulose UbiE: B753_RS0112315 GDP quinone pyridoxamine hydroxymethylpyrimidine/ synthetase: acetyltransferase: sn-glycerol sn-glycerol RlmL: lesion B753_RS0111315 B753_RS0100245 ARP an apo acyl- 7,8- B753_RS0101865 thiaminase tRNA ligase: acetyl phosphate degradation L-alanyl-γ-D-glutamyl-L- ethanolamine 1,4-benzoquinol ser 3'-AMP a [cysteine desulfurase]- 4-phosphate 6-methoxy-3- synthase PqqC: 5'-phosphate B753_RS0100040 B753_RS0111660 3-phosphate junction B753_RS0115195 dihydropteroate II: tenA phosphomethylpyrimidine B753_RS0110865 (S)-4-hydroxy- 3-phosphate 7 carrier protein B753_RS0113205 an L-isoleucyl- lysyl-D-alanyl-D-alanine formation of two an N - an alcohol butan-1-al [scaffold protein- holo-ACP synthase: methyl-2-all- adenosylcobinamide- oxidase: pdxH kinase: B753_RS0108840 Ile 2-oxohexanoate coproporphyrinogen III [tRNA ] acyl-CoA D-gluconate 2069 6,7-dimethyl-8- bifunctional 5-(2-hydroxyethyl) succinyl-CoA 2-oxoglutarate acetate kinase: intact strands methylguanine lipid A MsbA lipid A (2Fe-2S)] complex B753_RS0111535 trans-octaprenyl- GDP Ile synthetase: tetrahydrofolate pyrroloquinoline quinone PLP -4-methylthiazole a tRNA NADH repair B753_RS0111655 gluconokinase: in 23S rRNA ribityllumazine 4'-phosphopantetheinyl coproporphyrinogen 1,4-benzoquinol ribazoletransferase: HMP-P B753_RS0103445 synthase/ B753_RS0111630 synthase: transferase: III oxidase: B753_RS0118340 hydroxyethylthiazole 3-[(3aS,4S,7aS)-7a-methyl- D-gluconate dihydrofolate hydroxymethylpyrimidine/ acetate B753_RS0100480 B753_RS0101850 B753_RS0106880 kinase: NADH 1,5-dioxo-octahydro-1H- 6-phosphate a (2R)-2-hydroxy 2-methoxy-6-all 3-(all-trans- 967 1939 predicted a [co-chaperone]- phosphomethylpyrimidine 2-amino-6-[1-hydroxyethyl]- adenosylcobinamide a cytosine a uracil propan-1-ol butan-1-ol a holo acyl- synthase: B753_RS0107985 1-propanal pyruvate inden-4-yl]propanoyl-CoA even numbered trans-nonaprenyl- glycerophosphoglycerol nonaprenyl) acetyl-CoA ABC [scaffold protein- adenosylcobalamin kinase: B753_RS0108840 7-methyl-7,8-dihydropterin in 16S rRNA dITP in 23S rRNA taurine 6,7-dimethyl-8-(1- carrier protein B753_RS0115870 protoporphyrinogen IX 3-demethylubiquinol-8 4-methyl-5-(2- 2-oxoglutarate 2-amino-4-hydroxy-6- straight chain 1,4-benzoquinol benzene-1,2-diol bifunctional 16S rRNA acetyl-CoA NAD(P)- NAD(P)- transporter taurine (2Fe-2S)] complex 5'-phosphate superpathway of thiamine diphosphate biosynthesis II leu bifunctional glycerophosphoryl bifunctional 3- 23S rRNA D-ribityl)lumazine 7,8-dihydrofolate phosphooxyethyl) leucine--tRNA ligase: hydroxymethyldihydropteridine adenosylcobinamide non-canonical purine protoporphyrinogen HMP-PP dehydrogenase 2,3,4-saturatedlong-chain-acyl- demethylmenaquinone diester demethylubiquinone 3- (cytosine(967)-C(5) carboxylase (uracil(1939)-C(5)) dependent alcohol dependent alcohol of taurine SSQ1 chaperone: monoglutamate 3-demethylubiquinone- thiazole B753_RS0111470 an L-leucyl- C1 Compound Utilization and Assimilation diphosphokinase: folK kinase/ )-methyltransferase NTP pyrophosphatase, carboxyl transferase dehydrogenase: riboflavin synthase: oxidase HemJ: E1 component: 5-hydroxy-3-[(3aS,4S fatty acidCoA synthetase: methyltransferase/2- phosphodiesterase: O-methyltransferase/2- -methyltransferase dehydrogenase: B753_RS0107925 8 3-O- a ThiS sulfur- [tRNA Leu ] adenosylcobinamide- RsmB: RdgB/HAM1 family: rdgB subunit beta: B753_RS0111315 B753_RS0107295 B753_RS0108655 cys B753_RS0102795 (R)-NADHX ,5R,7aS)-7a-methyl-1,5- 2-amino-4-hydroxy-6- B753_RS0112080 methoxy-6-polyprenyl-1,4- B753_RS0106215 octaprenyl-6-hydroxy RlmD: B753_RS0111315 Peptide RS0102030 Peptide a [chaperone-ATP]- methyltransferase: carrier protein thiamine phosphate a tRNA Leu propanoyl-CoA a (R)-2-hydroxy phosphate B753_RS0100140 nucleoside triphosphate B753_RS0115865 menaquinol-6 biosynthesis bifunctional dioxo-octahydro-1H- formaldehyde oxidation hydroxymethyldihydropteridine [+ 4 isozymes] benzoquinol methylase glycerophosphodiester phenol methylase: a 5- B753_RS0103505 NAD(P)- NAD(P)- [co-chaperone]- B753_RS0110940 adenosylcobalamin cysteine synthase: formaldehyde oxidation even numbered guanylyltransferase: a 5-methylcytosine 967 pyrophosphohydrolase: riboflavin protoporphyrin IX ADP-dependent VII (THF pathway) pyrophosphokinase: phosphodiesterase: [+ 4 isozymes] 1939 dependent alcohol dependent alcohol B753_RS0101475 inden-4-yl]propanoyl-CoA diphosphate AMP straight chain 6-methoxy-3-methyl-2-UbiE: B753_RS0112315 2-methoxy- B753_RS0110940 methyluracil [scaffold protein- a 7,8-dihydrofolate desulfurase: NAD(P)H-hydrate II (glutathione-dependent) B753_RS0103160 B753_RS0115815 B753_RS0118320 in 16S rRNA B753_RS0103490 dehydrogenase: dehydrogenase: demethylmenaquinol-6 ubiquinol-8 [1-(2-amino-7-methyl-4-oxo- 2,3,4-saturated all-trans-nonaprenyl- 6-(all-trans- malonyl-CoA in 23S rRNA Peptide RS0102345 Peptide (2Fe-2S)] complex bifunctional ferrochelatase: B753_RS0108530 superpathway of glycolysis and the Entner-Doudoroff pathway dehydratase/ formaldehyde sn-glycerol adenosyl-cobinamide dIMP B753_RS0100245 B753_RS0100245 bifunctional an [L-cysteine a carboxy- formaldehyde 7,8-dihydro-3H-pteridin- fatty acyl CoA 1,4-benzoquinol glycerol nonaprenyl)phenol val RS0104365 val riboflavin kinase/ dihydrofolate B753_RS0112170 thiamine NAD(P)H-hydrate 3-phosphate phosphate SSQ1 chaperone demethylmenaquinone reductase: desulfurase]-S- adenylated-[ThiS val glutathione- 6-yl)]ethyl diphosphate 1-propanal butan-1-al FAD synthetase: phosphate valine--tRNA ligase: D-glucopyranose epimerase: (2E)-3-[(3aS,4S,5R,7aS) ATPase: B753_RS0110870 methyltransferase/2- B753_RS0111785 protoheme D-glyceraldehyde sulfanyl-L-cysteine sulfur-carrier protein] 6-phosphate -5-hydroxy-7a-methyl-1- a 5,10- dependent B753_RS0102610 B753_RS0113730 Mg 2+ RS0112265 Mg 2+ B753_RS0107925 methoxy-6-polyprenyl-1,4- 3-phosphate an L-valyl- (S)-NADHX oxo-octahydro-1H-inden- methylenetetrahydrofolate formaldehyde- a tetrahydrofolate [tRNA Val ] 2-methoxy-6-all cytidine 2',3'-cyclic DNA with adenine:7,8- FMN benzoquinol methylase cysteine gly 4-yl]prop-2-enoyl-CoA activating protein: a ring-opened 7- 3-aci- a peptide with adenine 1518 / 4-(cytidine 5'- 1-deoxy-D-xylulose- a tRNA Val ATP-dependent bifunctional coniferaldehyde phytol a [chaperone- UbiE: B753_RS0112315 desulfurase: trans-heptaprenyl- an N-terminal 1519 monophosphate diphospho)-2-C- dihydro-8- an [2Fe-2S] 5-phosphate methylenetetrahydrofolate B753_RS0117865 methylguanine in DNA nitropropanoate adenine in 16S rRNA XTP IMP bifunctional NADH-hydrate S-(hydroxymethyl) 1,4-benzoquinol multifunctional tRNA 2+ 2+ ADP]-[disordered- menaquinol-6 B753_RS0108530 bifunctional DNA- nitronate bifunctional Xaa-L-prolinecytosol 16S rRNA methyl-D-erythritol4-diphosphocytidyl- coniferyl aldehyde oxoguanine mismatchA/G-specific NAD(P)- Mg RS0106825 Mg cluster protein riboflavin kinase/ synthase: dehydratase: dehydrogenase/ glutathione nucleotidyltransferase/ non-canonical purine 5'-nucleotidase SurE: form scaffold superpathway of thiamine diphosphate biosynthesis I formamidopyrimidine monooxygenase: demethylmenaquinone aminopeptidase: (adenine(1518)-N(6)/ 2C-methyl-D- dehydrogenase: adenine dependent alcohol FAD synthetase: B753_RS0106870 glucose-6- B753_RS0113730 3-[(3aS,4S,5R,7aS)-5- methenyltetrahydrofolate 2',3'-cyclic NTP pyrophosphatase, B753_RS0101640 protein] complex S-(hydroxymethyl) glycosylase/ B753_RS0101385 methyltransferase/2- B753_RS0107315 adenine(1519)-N(6))- erythritol kinase: B753_RS0114870 glycosylase: dehydrogenase: B753_RS0110870 1-deoxy-D-xylulose a thiocarboxy- phosphate cyclohydrolase: RdgB/HAM1 family: rdgB 2-iminoacetate alanine-- hydroxy-7a-methyl-1-oxo- glutathione DNA-(apurinic or dimethyltransferase phosphodiesterase/ coniferyl aldehyde bifunctional B753_RS0111315 [ThiS-Protein] NADH B753_RS0100875 nitronate methoxy-6-polyprenyl-1,4- Xaa-Pro 2-phospho-4-(cytidineB753_RS0108785 mutY cys 5-phosphate ala isomerase: octahydro-1H-inden-4-yl]- apyrimidinic site) lyase: 2' nucleotidase/ nucleoside triphosphate metallophosphatase/ allantoin RS0101285 allantoin FAD tRNA ligase: 6-phospho dehydrogenase/ monooxygenase: benzoquinol methylase aminopeptidase: RsmA: dehydrogenase: an apurinic site NAD(P)- AIR B753_RS0111085 3-hydroxypropanoyl-CoA a 5,10- 2'phosphatase: 5'-diphospho)-2-C- pyrophosphohydrolase: adenine 5'-nucleotidase: B753_RS0115125 class III alcohol B753_RS0116045 B753_RS0105515 6 B753_RS01107851518 B753_RS0111825 an [Fe-S cluster a [disordered- 10 an L-alanyl- D-glucono- fatty acid oxidation 2,6-diamino-4- 6-methoxy-3-methyl-2-UbiE: B753_RS0112315 B753_RS0101940 within DNA dependent alcohol cysteine thiazole synthase: N -formyl-tetrahydrofolate biosynthesis methenyltetrahydrofolate [unspecified a peptide with N -dimethyladenine B753_RS0117120 methyl-D-erythritol B753_RS0103490 B753_RS0118870 Ala 1,5-lactone dehydrogenase: an apurinic site a proteinogenic 6 1519 ferulate dehydrogenase: biosynthesis form [Fe-S] cluster desulfurase: B753_RS0116745 [tRNA ] complex subunit hydroxy-5-(N-methyl) degradation nitrite 3-oxopropanoate all-trans-heptaprenyl- an N-terminal /N -dimethyladenine phosphomethylpyrimidine Ala bifunctional B753_RS0117200 within DNA 3'-cmp XMP inosine chaperone]-ATP scaffold protein] B753_RS0108530 a tRNA alpha FadB: formamidopyrimidine 1,4-benzoquinol amino acid in 16S rRNA B753_RS0100245allantoin RS0108475 allantoin synthase: B753_RS0107425 methylenetetrahydrofolate products] L-proline an [L-cysteine 2-[(2R,5Z)-2-carboxy- a tetrahydrofolate B753_RS0112545 [+ 2 isozymes] phytenal molybdenum cofactor biosynthesis desulfurase]-S- a ThiS sulfur- 4-methylthiazol-5(2H)- 3-[(3aS,4S,5R,7aS)-5- dehydrogenase/ carrier protein HMP-P D-gluconate hydroxy-7a-methyl-1-oxo- methenyltetrahydrofolate S-formylglutathione sulfanyl-L-cysteine ylidene]ethyl phosphate F6P + + 6-phosphate octahydro-1H-inden-4- cyclohydrolase: K KdpB K cysteine hydroxymethylpyrimidine/ methionine synthase: a 2-methoxy-6-all- 6-methoxy-2-all- (25S)-3- yl]-3-oxopropanoyl-CoA S-formylglutathione 2-all trans-hexaprenyl- 1-(18-hydroxyoleoyl)- GTP desulfurase: phosphomethylpyrimidine B753_RS0109665 asn phosphogluconate fructose 1,6- B753_RS0100875 a (6S)-5- citrate NAD + NADPH (R)-NADPHX (S)-NADHX hydrolase: fghA 6-methoxyhydroquinone trans-polyprenyl- trans-octaprenyl- glu oxocholest- coenzyme A ethylphosphate B753_RS0108530 dehydratase: 10 hypoxanthine PRPP formyltetrahydrofolate sn-glycrol 3-phosphate cys ATP kinase: B753_RS0108840 methionine synthase: bisphosphatase: an N - bifunctional 1,4-benzoquinol 1,4-benzoquinone 4-en-26-oate bifunctional bifunctional bifunctional a [ThiI sulfur- a carboxy- 2-(2-carboxy-4- an L-asparaginyl- B753_RS0111645 acetyl-CoA C- S-formylglutathione bifunctional bifunctional bifunctional acyl-CoA 1-acyl-sn-glycerol- NAD(P)(+) acid phosphatase: GTP 3',8- D-glyceraldehyde B753_RS0104760 B753_RS0105855 formyltetrahydrofolate xanthine predicted methylthiazol-5- [tRNA Asn ] hydrolase: fghA demethylmenaquinone synthetase: 3-phosphate aconitate hydratase transhydrogenase ADP-dependent ADP-dependent cysteine carrier protein]-S- adenylated-[ThiS HMP-PP acyltransferase: phosphoribosyltransferase: demethylmenaquinone demethylmenaquinone tetrahydrofolate B753_RS0111225 cyclase 3-phosphate Asn β methyltransferase/2- 2/2-methylisocitrate NAD(P)H-hydrate NAD(P)H-hydrate + ATP-driven + sulfanyl-L-cysteine sulfur-carrier protein] yl)ethyl phosphate tRNA KDGP -D-fructose 1,6- B753_RS0118720 formyltetrahydrofolate methyltransferase/2- methyltransferase/2- synthase/ B753_RS0100040 acyltransferase: (Re/Si-specific): alkaline K K desulfurase: MoaA: moaA tyr formate B753_RS0117330 dehydratase: transporter 1-deoxy-D-xylulose- dihydrofolate reductase: bisphosphate [+ 4 isozymes] deformylase: purU methoxy-6-polyprenyl-1,4- methoxy-6-polyprenyl-1,4- methoxy-6-polyprenyl-1,4- dihydrofolate acyl-CoA 1-[18-hydroxyoeoyl]-2-B753_RS0110815 B753_RS0103550 phosphatase: dehydratase/ dehydratase/ B753_RS0108530 (8S)-3',8-cyclo-7,8- DHAP hypoxanthine B753_RS0103095 of K+ an [L-cysteine a carboxy-adenylated AIR 5-phosphate thiamine phosphate B753_RS0111785 fructose- benzoquinol methylase benzoquinol methylase benzoquinol methylase synthetase: [18-hydroxy-lioleoyl]-sn B753_RS0103555 B753_RS0100895 NAD(P)H-hydrate NAD(P)H-hydrate dihydroguanosine phosphoribosyltransferase: hpt synthase: desulfurase]-S- [small subunit of synthase: synthase: 2-dehydro-3-deoxy- bisphosphate 3-[(3aS,4S,5R,7aS)- formate UbiE: B753_RS0112315 UbiE: B753_RS0112315 UbiE: B753_RS0112315 B753_RS0103445 -glycerol 3-phosphate aconitate hydratase B753_RS0103560 epimerase: epimerase: 5'-triphosphate glycine cleavage 2-all-trans-hexaprenyl- a 6-methoxy-3-methyl- 3-methyl-6-methoxy- B753_RS0115870 (25S)-3- ethanol a metal a metal phosphomethylpyrimidine B753_RS0106870 B753_RS0101475 a 7,8-dihydrofolate a 5-methyltetrahydrofolate phosphogluconate triose-phosphate acetyl-CoA 5-hydroxy-7a-methyl- IMP a (6S)-5- AcnA: acnA + B753_RS0113730 B753_RS0113730 RS0110145 sulfanyl-L-cysteine molybdopterin synthase] cyclic pyranopterin aspartate-- aldolase class II: 6-methoxy-3-methyl- 2-all-trans-polyprenyl- 2-octaprenyl-1,4- oxocholest-4- NADP NADH cation cation synthase: B753_RS0107425 a thiocarboxy- serine system protein H: gcvH asp aldolase: isomerase: 1-oxo-octahydro-1H- formyltetrahydrofolate monophosphate 1-deoxy-D-xylulose tRNA ligase: B753_RS0113545 1,4-benzoquinol 1,4-benzoquinol benzoquinone en-26-oyl-CoA D-threo-isocitrate (S)-NADPHX NADH 2-iminoacetate [ThiS-Protein] hydroxymethyltransferase: glyA B753_RS0111640 B753_RS0112425 5-phosphate B753_RS0115730 indene-4-carboxyl-CoA synthase: HMP-P thiamine phosphate an L-aspartyl- thymidylate asp a metal B753_RS0114070 [tRNA ] Degradation/Utilization/Assimilation - Other a metal RS0112350 thiazole synthase: folate transformations I asp D-glyceraldehyde NAD de novo biosynthesis a thiocarboxylated thiamine- synthase: thyA 3-oxo-2-(cis- a 3-(all-trans 527 2251 a cis,cis- cation cyclic pyranopterin hydroxymethylpyrimidine/ tRNA β a 7,8-dihydro-8- 3-(all-trans-heptaprenyl) a guanine guanosine sn-glycerol cation I (from aspartate) [small subunit of B753_RS0116745 phosphate 3-phosphate poly- -1,6-N-acetyl-D-glucosamine nicotinate PRPP 2'-pentenyl)- -polyprenyl) delta13,25-3- (S)-NADPHX phosphomethylpyrimidine bifunctional (5R,7aS)-5-hydroxy- oxoguanine in DNA benzene-1,2-diol in 16S rRNA in 23S rRNA 3-phosphate ser phosphate Pentose Phosphate Pathways octane oxidation poly-beta-1,6-N-acetyl- nicotinate benzene-1,2-diol molybdopterin synthase] kinase: B753_RS0108840 a tetrahydrofolate kinase: thiL a (6S)-5-formyltetrahydrofolate 7a-methyl-1-oxo- acrylonitrile bifunctional DNA- bifunctional 3- cyclopentane-1- bifunctional 3- ribosomal RNA 23S rRNA glycerol-3- hydroxyC44:2- bifunctional 2-[(2R,5Z)-2-carboxy- methylenetetrahydrofolate D-glucosamine N- threonine/serine asp 3,5,6,7-tetrahydro-2H- degradation I formamidopyrimidine phosphoribosyltransferase: demethylubiquinone 3- (3-oxooctanoyl) small subunit (guanosine(2251) phosphate 1-O- [acp] 3-oxoacyl-ACP ADP-dependent a metal a metal molybdopterin 4-methylthiazol-5(2H)- dehydrogenase/ 5-formyltetrahydrofolate Aldehyde Degradation acetyl-CoA C- demethylubiquinone 3- dehydratase: RS0112360 HMP-PP thiamine diphosphate methylenetetrahydrofolate pentose phosphate pathway (non-oxidative branch) indene-4-carboxyl-CoA NADH deacetylase PgaB: pgaB glycosylase/ pncB O-methyltransferase/2- -CoA methyltransferase -2'-O)- acyltransferase reductase FabG: NAD(P)H-hydrate cation cation L-aspartate oxidase: synthase: ylidene]ethyl phosphate methenyltetrahydrofolate cyclo-ligase: tyrosine-- acyltransferase: O-methyltransferase/2- B753_RS0101750 tyr 13-DPG acrylonitrile poly-beta-1,6-N-acetyl- DNA-(apurinic or nicotinate octaprenyl-6-hydroxy 7 G: B753_RS0113520 methyltransferase PlsB: B753_RS0108855 dehydratase/ B753_RS0105675 formyltetrahydrofolate reductase [NAD(P)H]: metF cyclohydrolase: B753_RS0107660 tRNA ligase: octaprenyl-6-hydroxy an N - B753_RS0114065 D-ribulose methylglyoxal degradation I D-glucosamine N- B753_RS0118720 L-serine thiamine phosphate B753_RS0100875 apyrimidinic site) lyase: phosphoribosyltransferase: phenol methylase: 3-oxo-2-(cis- phenol methylase: methylguanine 527 RlmB: α ωB753_RS0106790 a cis,cis-[+ 2 isozymes] NAD(P)H-hydrate 2-iminosuccinate deformylase: purU B753_RS0107720 an L-tyrosyl- 5-phosphate [+ 4 isozymes] 1-C16:0- , - ammonia-lyase: a metal a metal synthase: a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate phosphoglycerate a reduced deacetylase PgaB: pgaB B753_RS0116045 B753_RS0111275 B753_RS0110940 2'-pentenyl)- B753_RS0110940 B753_RS0112455 delta13,25-3- epimerase: [tRNA Tyr ] (5R,7aS)-7a-methyl-1,5- octane acetyl-CoA a 2-methoxy- in 16S rRNA 2-O- dicarboxyl-2- B753_RS0101080 quinolinate kinase: pgk rubredoxin methylglyoxal partially deacetylated poly-β- an apurinic site 7,8-dihydro- 2-methoxy-6-(all-trans cyclopentane-1- oxo-C44:2-[acp] B753_RS0113730 cation cation molybdopterin B753_RS0101475 Tyr acrylamide NaMN 2251 a tRNA dioxo-3,5,6,7-tetrahydro- acetate within DNA 6-(all-trans- methylguanosine lysophosphatidate pyruvate RS0102330 synthase NadA: bifunctional ribulose-phosphate ribose-5-phosphate lactoylglutathione 1,6-N-acetyl-D-glucosamine 8-oxoguanine -heptaprenyl)phenol hexanoyl-CoA 3-phospho- 2H-indene-4-carboxyl-CoA alkane 1- polyprenyl)phenol in 23S rRNA NADPH ala ala B753_RS0109785 molybdopterin 10 methylenetetrahydrofolate 3-epimerase: isomerase: an N - D-glycerate monooxygenase: amidase: lyase: gloA adenylyltransferase: thiamine salvage IV (yeast) thiamine phosphate glycine dehydrogenase/ B753_RS0109830 B753_RS0114535 (R)-S- formyltetrahydrofolate B753_RS0118215 B753_RS0104000 leu RS0109390 leu quinolinate B753_RS0114075 methionine cleavage methenyltetrahydrofolate 2,3-bisphosphoglycerate- lactoylglutathione thiamine salvage II an odd numbered 3-oxo-2-(cis- uridine 2'3'-cyclic 1402 a cis,cis- 6 37 1-stearoyl- a cytidine molybdopterin thiamine- synthase: system cyclohydrolase: tryptophan- independent D-xylulose D-ribose 5- (3R)-2-(2-carboxyethyl)- acrylate N -dimethylallyladenosine a sulfurated demethylmenaquinol-4 a ribonucleoside an L-aspartyl- sn-glycerol quinolinate thiamine bifunctional a tRNA Trp 1-octanol hydroxyacylglutathione straight chain a palmitoyl-[acp] sn-glycerol 2'-pentenyl)- monophosphate delta11,23-3- phosphate protein a (6S)-5- phosphoglycerate 5-phosphate phosphate 3-methyl-6-oxocyclohex- in 16S rRNA diphosphate [tRNA Asn ] 3-phosphate dGDP adenine dinucleotide B753_RS0109665 4-amino-2-methyl-5- B753_RS0100875 -tRNA hydrolase: gloB in tRNA [sulfur carrier] 2,3,4-saturated cyclopentane-1- multifunctional tRNA 16S rRNA phosphoribosyltransferase kinase: thiL H: gcvH methylenetetrahydrofolate formyltetrahydrofolate mutase: 1-ene-1-carboxyl-CoA succinate bifunctional 1-acyl-sn-glycerol-3-phosphate ribonucleoside- Asp-tRNA(Asn) hydroxyC42:2- glycerol-3- molybdopterin methionine pyrimidinemethanol ligase: trpS an L-tryptophanyl- long-chain-acyl- nucleotidyltransferase/ ribonucleoside- choline RS0117985 choline (decarboxylating): thiaminase dehydrogenase/ an N 10 -formyltetrahydrofolate dehydrogenase, fatty acid demethylmenaquinone 3-phosphate (3-oxohexanoyl) (cytidine(1402)-2'-O) diphosphate /Glu-tRNA(Gln) [acp] 3-oxoacyl-ACP phosphate 1-O- Trp B753_RS0107330 transketolase: acetyl-CoA C- molybdenumtransferase synthase: hydroxymethylpyrimidine/ [tRNA ] (R)-lactate CoA synthetase: -CoA 2',3'-cyclic -methyltransferase: reductase: reductase FabG: diphosphate B753_RS0110990 II: tenA thiamine diphosphate methenyltetrahydrofolate 5-formyltetrahydrofolate B753_RS0104770 hydrophobic methyltransferase/2- acyltransferase: amidotransferase: acyltransferase MoeA: B753_RS0114075 B753_RS0104760 phosphomethylpyrimidine trp 2-phospho- B753_RS0112080 acyltransferase: phosphodiesterase/ reductase: cyclohydrolase: cyclo-ligase: membrane anchor methoxy-6-polyprenyl-1,4- B753_RS0110815 a 2'-O- rsmI B753_RS0109225 gatB B753_RS0108855 PlsB: NaMN bifunctional kinase: B753_RS0108840 D-glycerate [+ 2 isozymes] 1-octanal [+an 4 isozymes]odd numbered 1-stearoyl- B753_RS0118720 2' nucleotidase/ B753_RS0109225 MoO -molybdopterin bifunctional B753_RS0100875 B753_RS0107660 9-carboxy-6-methyl-3,7- benzoquinol methylase 3-oxo-2-(cis- 1402 B753_RS0109235 a cis,cis-[+ 2 isozymes] B753_RS0106790 choline RS0104975 choline 2 4-amino-2-methyl-5- 5-(2-hydroxyethyl) 5-(2-hydroxyethyl) protein: sdhD 2-methylsulfanyl-N 6 - straight chain 2-palmitoyl- methylcytidine a 2'- B753_RS0102380 1-(18- cofactor methylenetetrahydrofolate dioxononanoyl-CoA an unsulfurated diphosphate AMP UbiE: B753_RS0112315 acyl-carrier protein 2'-pentenyl)-[+ 4 isozymes] 2'phosphatase: an L-asparaginyl- delta11,23-3- B753_RS0109235 pyrimidinemethanol -4-methylthiazole methylenetetrahydrofolate -4-methylthiazole HMP-P enolase: D-sedoheptulose D-glyceraldehyde 4-trimethylaminobutyraldehyde 37 in 16S rRNA deoxyribonucleoside hydroxyoleoyl) met 5'-deoxyadenosine dimethylallyladenosine 2,3,4-saturated sn-glycerol acetyl-CoA B753_RS0117120 Asn dehydrogenase/ dehydrogenase/ a 5,10- B753_RS0114630 [sulfur carrier] cyclopentane- [tRNA ] oxo-C42:2-[acp] GDP hydroxymethylpyrimidine/ hydroxyethylthiazole hydroxyethylthiazole NAD salvage 7-phosphate 3-phosphate dehydrogenase: pyruvate in tRNA fatty acyl CoA menaquinol-4 3-phosphate 5'-diphosphate -sn-glycrol methenyltetrahydrofolate methenyltetrahydrofolate methenyltetrahydrofolate hydroxymethylpyrimidine/ threonine-- acetyl-CoA C- B753_RS0104990 1-butanoyl-CoA 3'-UMP phosphomethylpyrimidine kinase: serine kinase: pathway III (to thr phosphoenol 3-phosphate met RS0104325 met nicotinate adenine cyclohydrolase: cyclohydrolase: phosphomethylpyrimidine tRNA ligase: acyltransferase: kinase: B753_RS0108840 B753_RS0107985 hydroxymethyltransferase: glyA B753_RS0107985 nicotinamide riboside) pyruvate transaldolase: tal dinucleotide phosphopantothenate biosynthesis I 4-methyl-5-(2- B753_RS0100875 B753_RS0100875 kinase: B753_RS0108840 B753_RS0103440 an L-threonyl- B753_RS0118720 octanoate 4-methyl-5-(2- NADP + phosphoenolpyruvate HMP-P Thr a [2-oxoglutarate- 1-palmitoyl- 1-stearoyl- 3-(all-trans 1402 2030 an [amino group carrier a cis,cis- a [pyruvate NAD+ synthetase, phosphooxyethyl) phosphooxyethyl) [tRNA ] [+ 4 isozymes] an apo [peptidyl- a cytidine adenine HMP-PP alkaline Thr synthase: D-erythrose long-chain-acyl- coenzyme A a palmitoleoyl-[acp] sn-glycerol a stearoyl-[acp] sn-glycerol DMKH2-10 -decaprenyl) protein]-C-terminal-γ- delta21,39-3- dehydrogenase ala ala glutamine NAD+ synthase: thiazole adeninyl adenosylcobamide a tRNA F6P dehydrogenase in 16S rRNA in 23S rRNA dADP RS0100135 3-methyl-2-oxobutanoate thiazole phosphatase: 4-phosphate CoA synthetase: SAM 6 a sulfurated [sulfur carrier] carrier protein] 6 B753_RS0108670 hydroxymethylpyrimidine/ B753_RS0103270 E2 protein] N - 4'-phosphopantetheinyl 3-phosphate 3-phosphate bifunctional benzene-1,2-diol ribosomal RNA 23S rRNA (L-glutamyl)-L-glutamate hydroxyC58:2- E2 protein] N met met dependent: thiamine phosphate a 5,10- biosynthesis from 7-carboxy-4-methyl- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- bifunctional 3- ribonucleoside- phosphomethylpyrimidine a 5-methyltetrahydrofolate B753_RS0100895 transketolase: acetyl-CoA B753_RS0112080 lipoyl demethylmenaquinone small subunit (adenine(2030)-N(6) [acp] 3-oxoacyl-ACP -dihydrolipoyl- B753_RS0108670 3-methyl-2-oxobutanoate synthase: methylenetetrahydrofolate superpathway of heme adenosylcobinamide-GDP thiamine phosphate 5-oxoheptanoyl-CoA octanoyl-L-lysine transferase: 3-phosphate 3-phosphate demethylubiquinone 3- acetylglutamate kinase: B753_RS0108840 acid phosphatase: pyruvate B753_RS0104770 [+ 4 isozymes] synthase: lipA methyltransferase )-methyltransferase reductase FabG: L-lysine dihydrolipoyl diphosphate hydroxymethyltransferase: B753_RS0101475 b biosynthesis from synthase: B753_RS0101850 acyltransferase: acyltransferase: methyltransferase/2- O-methyltransferase/2- kinase: argB + dehydrogenase: reductase: NAD B753_RS0111225 [+ 2 isozymes] lipoyl methoxy-6-polyprenyl-1,4- 4 H: B753_RS0117520 RlmJ: B753_RS0108855 panB methylenetetrahydrofolate uroporphyrinogen-III B753_RS0101475 octanoyl-CoA holo-ACP synthase: B753_RS0110815 B753_RS0110815 octaprenyl-6-hydroxy an N - an [amino group carrier thr RS0112965 thr HMP-PP thiamine adenine NAD + synthase: lipA a [2-oxoglutarate 1-palmitoyl-2- 1-stearoyl-2- lpdA B753_RS0109225 ser D-glyceraldehyde benzoquinol methylase 1402 6 B753_RS0117395 a cis,cis-[+ 2 isozymes] reductase [NAD(P)H]: metF nicotinate-nucleotide-- Secondary Metabolite Degradation an unsulfurated dehydrogenase B753_RS0111535 palmitoleoyl- stearoyl-sn phenol methylase: methylcytidine an N - protein]-C-terminal- a [pyruvate B753_RS0109235 2-dehydropantoate phosphate uroporphyrinogen-III serine--tRNA ligase: (2E)-7-carboxy-4-methyl- 5'-deoxyadenosine met acyl-carrier protein acyl-carrier protein UbiE: B753_RS0112315 delta21,39-3- [+ 2 isozymes] 3-phosphate 6 a holo [peptidyl- B753_RS0110940 in 16S rRNA methyladenine 2030 γ-(5-phospho-L- dehydrogenase 2-methyladeninyl uroporphyrinogen dimethylbenzimidazole thiamine NAD(+) B753_RS0102695 an L-seryl- 5-oxohept-2-enoyl-CoA [sulfur carrier] E2 protein] N 3',5'-ADP sn-glycerol -glycerol 3- 6-(all-trans- ADP carrier protein] menaquinol-10 glutamyl)-L-glutamate oxo-C58:2-[acp] E2 protein] N 6 adenosylcobamide biosynthesis decarboxylase: phosphoribosyltransferase: phosphate diphosphatase: [tRNA ser ] D-galactarate D-glucarate -lipoyl-L-lysine 3-phosphate phosphate decaprenyl)-2- in 23S rRNA thr RS0105310 thr ser enol-CoA hydratase: -lipoyl-L-lysine from adenosylcobinamide-GDP B753_RS0101865 cobT B753_RS0102005 a tRNA degradation II degradation II methoxy-phenol heme b biosynthesis 5-methoxy-6-methylbenzimidazolyl lipoate biosynthesis and adenine ribotide thiamine- B753_RS0105775 benzimidazolyl adenosylcobamide coproporphyrinogen III II (anaerobic) β thiamine 2-methyladenine adenosylcobamide biosynthesis incorporation III (Bacillus) phosphate phosphate NMN -alanine (R)-pantoate biosynthesis from Macromolecule Modification protein S-nitrosylation (3R)-7-carboxy-3-hydroxy-4- D-galactarate D-glucarate nicotinate-nucleotide-- from adenosylcobinamide-GDP coproporphyrinogen kinase: thiL a [pyruvate an apo-[LYS2 L- 1-myristoyl- an [RNA]-3'- a uridine 38- a cis,cis- a (3R)-3- met RS0104315 met and denitrosylation galactarate glucarate sn-glycerol DMKH2-13 NaMN urea-1-carboxylate pyrazinamide uroporphyrinogen-III adenosylcobinamide-GDP dimethylbenzimidazole 5-methoxy-6- adenosylcobinamide- bifunctional methyl-5-oxoheptanoyl-CoA dehydrogenase 2-aminoadipyl- coenzyme A a palmitoleoyl-[acp] sn-glycerol a stearoyl-[acp] ribonucleoside- 40 in tRNA delta19,37- hydroxyicosanoyl- an octanoyl-[acp] III oxidase: thiamine dehydratase: SAM a sulfurated [sulfur carrier] 3-phosphate uroporphyrinogen metallophosphatase/ fatty acid oxidation dehydratase: E2 protein] N 6 - carrier-protein] 3-phosphate bifunctional bifunctional 3'-phosphate allophanate RluA family 3-hydroxy- bifunctional [acp] pantoate--beta-alanine benzimidazole phosphoribosyltransferase: methylbenzimidazole lipoyl(octanoyl) B753_RS0106880 GDP diphosphate a [protein]- 4'-phosphopantetheinyl 1-acyl-sn-glycerol- glycerol-3- 3-hydroxyacyl- nicotinate-nucleotide-- pro garD gudD lipoyl RNA 3'-terminal hydrolase: atzF decarboxylase: ligase: B753_RS0103465 nicotinate-nucleotide-- cobT ribazoletransferase: 5'-nucleotidase: proline--tRNA ligase: L-cysteine complex subunit 5-dehydro-4- 5-dehydro-4- octanoyl-L-lysine transferase: 3-phosphate phosphate 1-O- demethylmenaquinone metallophosphatase/ pseudouridine C56:2-[acp]3-oxoacyl-ACP nicotinamidase/ [acyl-carrier- thiamine dimethylbenzimidazole transferase LipB: synthase: lipA phosphate cyclase: met RS0116255 met B753_RS0101865 dimethylbenzimidazole a [glycine-cleavage protoporphyrinogen IX B753_RS0118340 B753_RS0118870 B753_RS0102200 an L-prolyl- alpha FadB: deoxy-D-glucarate deoxy-D-glucarate B753_RS0101850 acyltransferase: acyltransferase methyltransferase/2- 5'-nucleotidase: allophanate synthase: reductase FabG: pyrazinamidase: protein] coproporphyrinogen III diphosphate 2-methyladenine phosphoribosyltransferase: B753_RS0102735 Coα-[α-(adenin- lipoyl B753_RS0116785 phosphoribosyltransferase: complex H protein] 5'-nucleotidase [tRNA Pro ] B753_RS0112545 5-dehydro-4- B753_RS0110815 PlsB: methoxy-6-polyprenyl-1,4- B753_RS0118870 an [RNA]-3'- hydrolase: B753_RS0112770 B753_RS0108855 B753_RS0100325 dehydratase (R)-pantothenate ribotide phosphate 5-methoxy-6-cobT protoporphyrinogen 9-yl)]-Coβ- 5-dehydro-4- synthase: lipA a [pyruvate holo-ACP synthase: 1-myristoyl-2- cobT N 6 -octanoyl-L-lysine SurE: a tRNA Pro 7-carboxy-4-methyl-3,5- deoxyglucarate deoxyglucarate B753_RS0111535 B753_RS0106790 benzoquinol methylase 5'-nucleotidase SurE: ribonucleoside-2',3'- B753_RS0110130 [+ 3 isozymes] a cis,cis-[+ 2 isozymes] amidase: FabZ: fabZ benzimidazole methylbenzimidazole oxidase HemJ: adenosylcobamide 5-methylbenzimidazolyl a [protein] 3- an unsulfurated dehydrogenase a holo-[LYS2 L- palmitoleoyl- 1-stearoyl- a pseudouridine 38- 5-methoxybenzimidazolyl 5'-deoxyadenosine met acyl-carrier protein UbiE: B753_RS0112315 delta19,37-3- a (2E)-icos- + + adenosylcobinamide- B753_RS0101640 dioxoheptanoyl-CoA dehydratase: dehydratase: 6 B753_RS0101640 cyclophosphate CO ammonium B753_RS0104000 H RS0113505 H pantothenate kinase: ribotide phosphate ribotide phosphate B753_RS0108655 5'-phosphate adenosylcobamide biosynthesis nitrosothio- [sulfur carrier] E2 protein] N 2-aminoadipyl- 3',5'-ADP sn-glycerol acyl-carrier protein sn-glycerol 2 40 in tRNA pyrazine-2- GDP adenosylcobamide biosynthesis 1-(β-D kdgD menaquinol-13 β-D-ribosylnicotinate oxo-C56:2-[acp] 2-enoyl-[acp] B753_RS0108975 adenosylcobinamide- from adenosylcobinamide-GDP L-alanine kdgD -lipoyl-L-lysine carrier-protein] 3-phosphate 3-phosphate carboxylate adenosylcobinamide- 5-hydroxybenzimidazolyl ribazoletransferase: protoporphyrin IX from adenosylcobinamide-GDP ribofuranosyl) acetyl-CoA C- protoporphyrinogen IX GDP a [lipoyl-carrier protein] 2,5- 2,5- (R)-4'-phosphopantothenate GDP adenosylcobamide biosynthesis B753_RS0118340 5-methylbenzimidazole NaMN 5-methoxybenzimidazole nicotinamide phenylalanine- acyltransferase: Coα-[α-(2- ribazoletransferase: N 6 -octanoyl-L-lysine Coα-[α-(adenin- dioxopentanoate dioxopentanoate NAD(P) ribazoletransferase: from adenosylcobinamide-GDP ferrochelatase: nicotinate-nucleotide-- nicotinate-nucleotide-- -tRNA ligase: B753_RS0118720 2-phospho-4-(cytidine 5'- (5E)-3-oxo- a cis,cis-delta9,27- a cis,cis- a (3R)-3- a (3R,5Z)-3- H + H + methyladenin-9-yl)]-Co B753_RS0118340 β glutathione- phe 2,5-dioxovalerate 2,5-dioxovalerate a single a damaged a [release factor]- B753_RS0118340 α α lipoyl B753_RS0112170 7-yl)]-Co - dimethylbenzimidazole an apo-[aryl- sn-glycerol DMK-12 transhydrogenase 5-hydroxybenzimidazole NaMN β Co -[ -(5-methoxy-6- dimethylbenzimidazole glutaredoxin B753_RS0103385 a [protein]- [+ 4 isozymes] dehydrogenase: dehydrogenase: stranded DNA coenzyme A diphospho)-2-C-methyl-D-erythritol a myristoyl-[acp] DNA pyrimidine dodec-5- L-glutamine 3-hydroxyC46:2- delta19,31-3- hydroxyhexacosanoyl- hydroxydodec- Coα-[α-(benzimidazolyl) -adenosylcobamide synthase: lipA adenosylcobamide phosphoribosyltransferase: carrier protein] 3-phosphate nicotinate-nucleotide-- methylbenzimidazolyl)]- phosphoribosyltransferase: B753_RS0103390 an L-phenylalanyl- S-nitrosoglutathione B753_RS0114910 exodeoxyribonuclease 2-C-methyl-D- bifunctional bifunctional DNA- enoyl-CoA peptide chain [acp] hydroxyC50:2- [acp] 5-enoyl-[acp] ]-Coβ-adenosylcobamide 5'-phosphate protoheme redox reactions L-cysteine B753_RS0114910 4'-phosphopantetheinyl glycerol-3- acetyl-CoA C- 3-oxoacyl-ACP 3-hydroxyacyl- 3-hydroxyacyl- protoporphyrin IX Coβ-adenosylcobamide lipoyl cobT cobT Phe 5-carboxy-2-methyl- VII large subunit: erythritol 2,4- demethylmenaquinone formamidopyrimidine release factor [acp] 3-oxoacyl-ACP dimethylbenzimidazole 5-methylbenzimidazole [tRNA ] acetyl-CoA β transferase: phosphate 1-O- acyltransferase: reductase FabG: [acyl-carrier- [acyl-carrier- 5'-phosphate synthase: lipA 5-methoxybenzimidazole glutathione Phe S-(hydroxymethyl) fatty acid -oxidation I F0F1 ATP phosphoribosyltransferase: 5'-phosphate a tRNA 3-oxopentanoyl-CoA 2-oxoglutarate 2-oxoglutarate B753_RS0110470 cyclodiphosphate methyltransferase/2- glycosylase/ N(5)-glutamine B753_RS0108855 reductase FabG: H + H + a [lipoyl-carrier ribotide phosphate ribotide phosphate glutathione B753_RS0101850 acyltransferase B753_RS0118720 protein] protein] synthase ferrochelatase: cobT synthase: methoxy-6-polyprenyl-1,4- DNA-(apurinic or methyltransferase: B753_RS0108855 6 exodeoxyribonuclease holo-ACP synthase: PlsB: [+ 2 isozymes] dehydratase dehydratase B753_RS0112170 5-hydroxybenzimidazole Coα-[α-(2- protein]-N -[(R)- menaquinol-7 biosynthesis adenosylcobinamide- adenosylcobinamide- dehydrogenase/ a (3Z)-alk-3- B753_RS0114150 [+ 4 isozymes] a cis,cis- VII: B753_RS0110475 B753_RS0106790 benzoquinol methylase apyrimidinic site) lyase: (3E)-dec-3- prmC a cis,cis-[+ 2 isozymes] FabZ: fabZ FabZ: fabZ ribotide phosphate methyladenin-7-yl)]-Co dihydrolipoyl]-L-lysine GDP a reduced class III alcohol enoyl-CoA B753_RS0111535 1-myristoyl- acetyl-CoA 5 delta9,27-3- Coα-[α-(benzimidazolyl) GDP ribazoletransferase: a single-stranded a ribonucleoside a holo-[aryl- 2-C-methyl-D-erythritol- UbiE: B753_RS0112315 B753_RS0116045 enoyl-CoA a [release factor]-N delta19,31-3- a (2E)-hexacos- a (2E,5Z)-dodeca- folate polyglutamylation Coα-[α-(5-methoxy-6- CMP + + protoheme β-adenosylcobamide all-trans- ribazoletransferase: B753_RS0118340 glutaredoxin dehydrogenase: 3',5'-ADP acyl-carrier protein sn-glycerol an apyrimidinic -methyl-L-glutamine oxo-C46:2-[acp] H RS0111805 H ]-Coβ-adenosylcobamide adenosylcobinamide- di-trans,poly-cis-undecaprenyl 1,4-dihydroxy- succinyl-CoA propanoyl-CoA ∆ 3 -cis-∆ 2 -trans-enoyl- oligodeoxyribonucleotide 5'-monophosphate carrier protein] 2,4-cyclodiphosphate oxo-C50:2-[acp] 2-enoyl-[acp] 3,5-dienoyl-[acp] methyl-benzimidazolyl)]- heptaprenyl B753_RS0118340 methionine- B753_RS0117200 3-phosphate menaquinol-12 GDP ribazoletransferase: β phosphate biosynthesis 2-naphthoate Coα-[α-(5-methoxybenzimidazolyl)]- met CoA isomerase: site in DNA a tetrahydrofolate Co -adenosylcobamide diphosphate Coα-[α-(5-methylbenzimidazolyl) thioredoxin glutaredoxin -tRNA B753_RS0118340 Coβ-adenosylcobamide 5'-phosphate an L-methionyl- S-(hydroxymethyl) B753_RS0112545 (2E,6E)-farnesyl ]-Coβ-adenosylcobamide pathway 3: grxC ligase: metG α α NAD IPP demethylmenaquinol-7 [elongator glutathione + + Co -[ -(5-hydroxybenzimidazolyl)]- 5'-phosphate a protein with a 5,6- a cis,cis-delta7,25- a cis,cis- a (3R)-3- a (3R)-3- H RS0113350 H diphosphate Met β (2R,3S)-2- β thiamine phosphorylation and di-trans,poly-cis- an oxidized elongator tRNA ] dehydrogenase/ oleate -oxidation a (2E)-2- 16-hydroxypalmitate AsbD acyl- linoleate sn-glycerol DMKH2-11 xylitol 20 bifunctional serine Co -adenosylcobamide 5'-phosphate reduced L- coenzyme A a palmitoyl-[acp] dihydrouracil 3-hydroxyC44:2- delta17,35-3- hydroxytetracosanoyl- hydroxyglutaryl- bifunctional tRNA Met acyl-CoA carrier protein 3-phosphate methylisocitrate tetrahydrofolate hydroxymethyltransferase: glyA salvage I transhydrogenation decaprenylcistransferase: thioredoxin class III alcohol enoyl-CoA enol-CoA hydratase: long-chain-acyl- long-chain-acyl- bifunctional NAD(P)-dependent in tRNA bifunctional [acp] hydroxyC54:2- [acp] [acp] methyl ester glutathione biosynthesis demethylmenaquinone α α cysteine residues (2E,5Z)- a 2,3,4-saturated synthetase: 4'-phosphopantetheinyl glycerol-3- tRNA 3-oxoacyl-ACP 3-hydroxyacyl- 3-hydroxyacyl- synthase/ 10 + di-trans,octa-cisuppS Co -[ -(5-methoxybenzimidazolyl) dehydrogenase: coenzyme A B753_RS0105775 3-hydroxybutyryl- a 2,3,4- CoA synthetase: CoA synthetase: alcohol dehydrogenase: an N - NAD B753_RS0100040 acyl-CoA transferase: phosphate 1-O- demethylmenaquinone dihydrouridine(20/ aconitate hydratase reductase FabG: [acp] 3-oxoacyl-ACP [acyl-carrier- [acyl-carrier- a 5,10- thiamine -undecaprenyl methyltransferase/2- Coα-[α-(5-methylbenzimidazolyl) ]-Coβ-adenosylcobamide B753_RS0113145 tetradecenoyl-CoA fatty acid saturated (3R)-3- B753_RS0111315 dihydrofolate formyltetrahydrofolate CoA epimerase: B753_RS0112080 B753_RS0101850 B753_RS0112080 methyltransferase/2- 2/2-methylisocitrate B753_RS0108855 reductase FabG: protein] NAD(+) kinase: diphosphate methoxy-6-polyprenyl-1,4- β [+ 4 isozymes] dehydrogenase: acyltransferase 20a) synthase DusA: protein] synthase: methylenetetrahydrofolate Coα-[α-(5-hydroxybenzimidazolyl) cys glu ]-Co -adenosylcobamide thioredoxin- S-(hydroxysulfenamide) B753_RS0112545 hydroxyacyl-CoA [+ 4 isozymes] [+ 4 isozymes] methoxy-6-polyprenyl-1,4- NAD(P)-dependent dehydratase: B753_RS0108855 bifunctional B753_RS0116835 undecaprenyl- benzoquinol methylase lysine- enol-CoA hydratase: B753_RS0101365 holo-ACP synthase: PlsB: B753_RS0103580 a cis,cis-[+ 2 isozymes] dehydratase dehydratase B753_RS0115870 ]-Coβ-adenosylcobamide disulfide Lys bifunctional glutamate-- + a tRNA glutathione a 2,3,4- benzoquinol methylase alcohol dehydrogenase: 20 B753_RS0103095 a cis,cis-[+ 2 isozymes] tetrahydrofolate thiamine NADP diphosphatase: UbiE: B753_RS0112315 -tRNA B753_RS0105775 [+ 18 isozymes] 16-hydroxypalmitoyl- B753_RS0111535 B753_RS01067901-palmitoyl- a uracil in tRNA delta7,25-3- FabZ: fabZ a (2E)- FabZ: fabZ tetrahydrofolate cysteine ligase: reductase: a 2,3,4-saturated saturated (3S)-3- AMP diphosphate a holo-[AsbD acyl- AMP diphosphate linoleoyl-CoA UbiE: B753_RS0112315 B753_RS0100245 cis-2- delta17,35-3- a (2E)-tetracos- synthase/ phosphate B753_RS0107875 ligase: lysS an L-lysyl- CoA 3',5'-ADP acyl-carrier protein sn-glycerol oxo-C44:2-[acp] enoylglutaryl- synthase/ NAD(P) trxB (3E,5Z)-tetradeca- fatty acyl CoA carrier protein] methylaconitate oxo-C54:2-[acp] 2-enoyl-[acp] γ B753_RS0100580 menaquinol-7 Lys hydroxyacyl-CoA menaquinol-11 D-xylopyranose a tetrahydrofolate dihydrofolate -L-glutamyl- undecaprenyl- [tRNA ] (S)-3-hydroxy-(5Z) 3,5-dienoyl-CoA 3-phosphate [acp] methyl ester dihydrofolate thiamine- transhydrogenase: NAD phosphorylation and dephosphorylation lipoate biosynthesis 3-hydroxyacyl-CoA synthase: L-cysteine diphosphatase: menaquinol-9 biosynthesis lys -tetradecenoyl-CoA synthase: base-degraded phosphate B753_RS0103550 and incorporation I hydroxylamine acyl-CoA dehydrogenase: B753_RS0115870 glutathione B753_RS0102460 a reduced acetyl-CoA C- B753_RS0115870 thiamine salvage kinase: thiL B753_RS0103555 + thioesterase: 10 NAD B753_RS0112545 a 2-methyl α,ω-9Z- α-D-mannose a cis,cis-delta5,23- a cis,cis- a (3R)-3- a (3R)-3- an N - synthase: thioredoxin demethylmenaquinol-9 B753_RS0109325 acyltransferase 18-hydroxystearate oleate a 3-oxohexacosanoyl- a 5,10- thiamine di-trans,octa-cis- an octanoyl-[acp] branched 2,3,4- 1-phosphate NADH 3-hydroxyC42:2- delta13,31- hydroxydocosanoyl- hydroxypimeloyl- formyltetrahydrofolate formylaminopyrimidine B753_RS0108260 NADPH bifunctional a 2,3,4-saturated FadA: a 2,3,4-saturated octadecenedioate 2'-deoxyadenosine [acp] methylenetetrahydrofolate diphosphate undecaprenyl phosphate lipoyl(octanoyl) [+ 5 isozymes] long-chain-acyl- saturated fatty acid acyl-CoA long-chain-acyl- phosphomannomutase/ NAD(+) [acp] 3-hydroxy [acp] [acp] methyl ester fatty acyl CoA B753_RS01125503-oxoacyl-CoA long-chain-acyl- 3-oxoacyl-ACP 3-oxoacyl-ACP 3-hydroxyacyl- 3-hydroxyacyl- alkaline demethylmenaquinone histidine-- Alcohol Degradation CoA synthetase: synthetase: CoA synthetase: phosphoglucomutase: adenosine deaminase: diphosphatase: C50:2-[acp]3-oxoacyl-ACP glutathione menaquinol-8 biosynthesis NAD(P) transferase LipB: his (3E,5Z)- CoA synthetase: reductase FabG: reductase FabG: [acyl-carrier- [acyl-carrier- phosphatase: methyltransferase/2- tRNA ligase: ammonium [+ 4 isozymes] B753_RS0112080 B753_RS0100040 B753_RS0112080 B753_RS0105260 B753_RS0109760 B753_RS0102005 reductase FabG: aminomethylpyrimidine transhydrogenase: NAD(+) kinase: a [lipoyl-carrier B753_RS0102735protein] tetradecadienoate B753_RS0112080 B753_RS0108855 B753_RS0108855 protein] protein] B753_RS0100895 methoxy-6-polyprenyl-1,4- B753_RS0111555 an L-histidyl- glycerol and glycerophosphodiester degradation adenosine deaminase: reduced β- B753_RS0108855 thiaminase B753_RS0103550 B753_RS0116835 N 6 -octanoyl-L-lysine [+ 4 isozymes] [+ 4 isozymes] [+ 4 isozymes] [+ 4 isozymes] phosphomannomutase/ [+ 2 isozymes] [+ 2 isozymes] dehydratase dehydratase guanylyl molybdenum demethylmenaquinol-8 acid phosphatase: benzoquinol methylase [tRNA His ] a 2-methyl ω-carboxy- B753_RS0115095 nicotinamide D- AMP a (3R)-3- a cis,cis- II: tenA B753_RS0103555 18-hydroxystearoyl- phosphoglucomutase: a cis,cis-[+ 2 isozymes] FabZ: fabZ FabZ: fabZ cofactor biosynthesis bifunctional B753_RS0111225 lipoyl synthase: lipA UbiE: B753_RS0112315 a tRNA His AMP diphosphate branched AMP diphosphate (9Z)-octadec- diphosphate AMP oleoyl-CoA ribonucleotide hydroxyhexacosanoyl- delta5,23-3- a (2E)- a glycerophosphodiester CoA AMP diphosphate B753_RS0111095 2'-deoxyinosine delta13,31-3- a (2E)-docos- MoO - 4-amino-2-methyl-5- lipoyl synthase: lipA menaquinol-9 acetyl-CoA 2,3,4-saturated [acp] oxo-C42:2-[acp] enoylpimeloyl- 2 demethylmenaquinone 9-enoyl-CoA D-mannopyranose oxo-C50:2-[acp] queuosine biosynthesis fatty acyl-CoA 2-enoyl-[acp] [acp] methyl ester molybdopterin pyrimidinemethanol methyltransferase/2- a [lipoyl-carrier protein]-N 6 - 6-phosphate NADP + cofactor molybdenum cofactor methoxy-6-polyprenyl-1,4- [(R)-dihydrolipoyl]-L-lysine glycerophosphodiester preQ guanylyltransferase: benzoquinol methylase 0 phosphodiesterase: glycine--tRNA (R)-4'- a 3-methyl- a nucleoside a cis,cis-delta7,19- a cis,cis- 1-myristoyl- a (3R,7Z)-3- guanylyl B753_RS0114045 UbiE: B753_RS0112315 gly NADPH- B753_RS0115815 a nucleoside L-arabinitol a 3-oxotetracosanoyl- ligase: glyQ glycerol phosphopantothenoyl- branched 2,3,4- decanoate a ribonucleic acid cyclic 3',5'- 3-hydroxyC38:2- delta17,29-3- sn-glycerol hydroxy-hexadec- molybdenum menaquinol-8 dependent triphosphate ATP H O [acp] B753_RS0106940 glycerophosphoryl L-cysteine saturated fatty acid long-chain-acyl- NAD(P)-dependent 2 monophosphate [acp] hydroxyC48:2- 3-phosphate 7-enoyl-[acp] cofactor Gly 7-cyano-7- Aromatic Compound Degradation bifunctional long-chain-acyl- DNA-directed 3-oxoacyl-ACP 3-oxoacyl-ACP 1-acyl-sn-glycerol- 3-hydroxyacyl- a glycyl-[tRNA ] diester CoA synthetase: alcohol dehydrogenase: type I secretion 3',5'-cyclic-nucleotide deazaguanine glycerol CoA synthetase: RNA polymerase reductase FabG: reductase FabG: [acp] 3-oxoacyl-ACP 3-phosphate [acyl-carrier- Gly phosphopantothenoylcysteine system permease/ a tRNA kinase: phosphodiesterase: B753_RS0112080 B753_RS0111315 phosphodiesterase: reductase FabG: reductase β decarboxylase/ B753_RS0112080 subunit alpha: B753_RS0108855 B753_RS0108855 acyltransferase: protein] aromatic compounds degradation via -ketoadipate glpK B753_RS0106215 [+ 4 isozymes] ATPase: B753_RS0100835 QueF: queF catechol degradation III benzoate degradation phosphopantothenate-- [+ 4 isozymes] B753_RS0106600 NAD(P)-dependent [+ 2 isozymes] [+ 2 isozymes] B753_RS0108855 1-myristoyl-2-B753_RS0110815 dehydratase 4-sulfocatechol a 3-methyl- B753_RS0110325 a nucleoside 5'- a (3R)-3- a cis,cis- preQ (ortho-cleavage pathway) I (aerobic) alcohol dehydrogenase: a cis,cis-[+ 2 isozymes] FabZ: fabZ 1 cysteine ligase CoaBC: coaBC branched [+ 2 isozymes] + hydroxytetracosanoyl- delta7,19-3- palmitoleoyl- a (2E,7Z)- protocatechuate degradation sn-glycerol diphosphate AMP diphosphate AMP decanoyl-CoA B753_RS0100245 H phosphate ADP monophosphate delta17,29-3- 4'-phosphopantetheine 2,3,4-saturated a ribonucleic acid [acp] oxo-C38:2-[acp] sn-glycerol hexadeca-2,7- methionine- tRNA guanosine(34) catechol benzoate 3-phosphate L-arabinopyranose oxo-C48:2-[acp] met 4-sulfocatechol fatty acyl-CoA 3-phosphate dienoyl-[acp] superpathway of aromatic amino acid biosynthesis Amino Acid Biosynthesis Metabolic Regulator transglycosylase protocatechuate 3,4- catechol 1,2- benzoate 1,2- superpathway of L- L-histidine biosynthesis L-lysine biosynthesis I L-alanine L-alanine L-arginine biosynthesis II (acetyl cycle) -tRNA protocatechuate Biosynthesis Tgt: dioxygenase: pcaH pcaG dioxygenase: isoleucine biosynthesis I biosynthesis I biosynthesis III ligase: metG an L-methionyl- catechol dioxygenase: catA 3,4-dioxygenase: D-erythrose B753_RS0115640 a cis,cis- 1-palmitoyl- [initiator tRNA Met ] cis,cis-muconate benA benB (15Z)- a reduced a [DNA]-3'- a 5'-phospho- 3-oxo-(9Z)- 3-oxododecanoyl- (2E)-dec-2- a (3R,5Z)-3- 4-phosphate N-acetylglutamyl- L-asparagine biosynthesis III (tRNA-dependent) ppGpp biosynthesis a 7-aminomethyl-7- 3-carboxy-cis,cis-muconate pcaH pcaG 3,5-cyclohexadiene- NAD + glycerol a cis,cis-delta5,17-3- a 3-oxopimeloyl- oxaloacetate PRPP asp 3-methyl-2- initiator tRNA Met catechol 1,2- tetracosenoate electron-transfer ubiquinone-6 hydroxyl [DNA] octadecenoyl-CoA CoA enoyl-CoA delta15,33- sn-glycerol hydroxy-tetradec- 34 1,2-diol-1-carboxylate DHAP hydroxyC36:2[acp] [acp] methyl ester oxobutanoate cys phosphate deazaguanosine muconate 3-sulfomuconate acyl-CoA DNA acetyl-CoA C- NAD(P)-dependent acetyl-CoA C- 3-hydroxy 3-phosphate 3-deoxy-7- aspartate/ branched-chain bifunctional dioxygenase: catA 3-carboxy- flavoprotein electron transfer 3-oxoacyl-ACP 3-oxoacyl-ACP 1-acyl-sn-glycerol- 5-enoyl-[acp]3-hydroxyacyl- ATP aspartate kinase: cysteine in tRNA cycloisomerase: (1R,6S)-1,6- synthetase: ligase acyltransferase alcohol dehydrogenase: acyltransferase enol-CoA hydratase: C52:2-[acp]3-oxoacyl-ACP phosphoheptulonate tyrosine/aromatic amino acid glutamate N- asp pppGpp cis,cis-muconate 3-sulfomuconate flavoprotein- reductase FabG: reductase FabG: 3-phosphate [acyl-carrier- phosphoribosyltransferase B753_RS0115120 desulfurase: tRNA preQ1(34) S- cis,cis-muconate B753_RS0103900 dihydroxycyclohexa- B753_RS0100040 (NAD(+)) FadA: B753_RS0111315 FadA: B753_RS0105775 reductase FabG: synthase: aminotransferase: transaminase: acetyltransferase/ bifunctional (p)ppGpp cycloisomerase: cycloisomerase: ubiquinone B753_RS0108855 B753_RS0108855 acyltransferase: protein] regulatory subunit: B753_RS0108530 2,4-diene-1- B753_RS0112550 B753_RS0112550 (S)-3- B753_RS0108855 B753_RS0118345 B753_RS0111125 L-aspartyl-4-phosphate amino-acid N-acetyl-gamma- adenosylmethionine B753_RS0114665 [+ 4 isozymes] oxidoreductase: LigA: ligA NAD(P)-dependent [+ 2 isozymes] [+ 2 isozymes] B753_RS0110815 dehydratase B753_RS0115135 B753_RS0115675 ala synthetase/guanosine- muconate B753_RS0114665 (+)-muconolactone a cis,cis- a (3R)-3- 1-palmitoyl-2- acetyltransferase ribosyltransferase- carboxylate:NAD+ [+ 4 isozymes] alcohol dehydrogenase: [+ 4 isozymes] hydroxydecanoyl- a cis,cis-[+ 2 isozymes] 3-deoxy-7- asp val glutamyl-phosphate 3',5'-bis(diphosphate) 3'- cycloisomerase: (2-carboxy-2,5-dihydro- (15Z)- B753_RS0112190an oxidized delta5,17-3- hydroxypimeloyl- palmitoleoyl- a (2E,5Z)-FabZ: fabZ ATP ArgJ: argJ isomerase QueA: 4-sulfomuconolactone oxidoreductase AMP diphosphate NMN AMP [DNA] (7Z)- B753_RS0100245 CoA delta15,33-3- aspartate- muconolactone tetracosenoyl-CoA + acetyl-CoA acetyl-CoA decanoyl-CoA phosphoheptulonate reductase: pyrophosphohydrolase: B753_RS0103900 5-oxofuran-2-yl)-acetate H ubiquinol-6 electron-transfer hexadecenoyl-CoA oxo-C36:2-[acp] [acp] methyl ester sn-glycerol tetradeca-2,5- phosphoribosyltransferase: semialdehyde B753_RS0115655 (decarboxylating): oxo-C52:2-[acp] synthase: amino-acid N- B753_RS0114550 an L-aspartyl- B753_RS0107220 tRNA processing delta- flavoprotein L-glyceraldehyde 3-phosphate dienoyl-[acp] aspartate kinase: acetylglutamate guanosine 3'- 34 B753_RS0110540 B753_RS0110630 dehydrogenase: Asn gln an epoxyqueuosine B753_RS0114575 B753_RS0115120 acetyltransferase: kinase: argB [tRNA ] bifunctional (p)ppGpp diphosphate 5'- (+)-muconolactone 4-carboxymuconolactone isomerase: catC asd N-acetyl-L- in tRNA 3-deoxy- 1-(5-phospho- B753_RS0110915 N-acetyl-L- synthetase/guanosine- triphosphate 3'- a polycistronic decarboxylase: (4,5-dihydro-5- catechol β glu glutamate 5- Asp-tRNA(Asn) carbamoyl- 1-stearoyl- a cis,cis- a (3R,6Z)-3- D-arabino- L-aspartyl- -D-ribosyl)-ATP L-aspartate 4- glutamate Carbohydrate Biosynthesis tRNA precursor B753_RS0101300 oxofuran-2-yl)-acetate 2-maleylacetate adenosylcobinamide- phenyl ribotide 3-oxo-(7Z)- 3-oxooctanoyl- a 3-oxoglutaryl- sn-glycerol ala semialdehyde /Glu-tRNA(Gln) 3',5'-bis(diphosphate) 3'- diphosphatase: muconolactone delta- a 2,3,4-saturated a 2,3,4-saturated 2- an acyl-[acyl- 3'-dephospho- glutathione fenclorim roseoflavin delta11,29- heptulosonate phosphoribosyl-ATP semialdehyde phosphate synthase: GDP phosphate sn-glycerol hexadecenoyl-CoA ATP CoA ATP 3-phosphate hydroxyoctadec- 4-phosphate N-acetylornithine amidotransferase: pyrophosphohydrolase: B753_RS0103500 isomerase: catC [+ 2 isozymes] 3-oxoadipate fatty acyl-[acp] lysophosphatidate carrier protein] CoA glutathione S- 5'-phosphate [acp] methyl ester 7-phosphate pyrophosphatase: B753_RS0100945 adenosylcobinamide- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol-3-phosphate acetyl-CoA C- acetyl-CoA C- 3-oxoacyl-ACP 3-hydroxy glycerol-3- 6-enoyl-[acp]3-hydroxyacyl- aminotransferase: B753_RS0103500 34 4-hydroxy- alanine gatB UDP-N-acetyl-D- a queuosine enol-lactonase: acyltransferase triphosphoribosyl- acyltransferase transferase: bifunctional C48:2-[acp]3-oxoacyl-ACP phosphate 1-O- 3-dehydroquinate aspartate- B753_RS0112335 B753_RS0114855 carB trehalose biosynthesis I quinate degradation I GDP 3-phosphate 3-phosphate reductase FabG: [acyl-carrier- tetrahydrodipicolinate racemase: alr B753_RS0102380 glucosamine biosynthesis I in tRNA pcaD dephospho- B753_RS0118125 synthase: semialdehyde β bifunctional [+ 9 isozymes] (4,5-dihydro-5-oxofuran-2-yl)-acetate ribazoletransferase: acyltransferase: acyltransferase: FadA: FadA: riboflavin kinase/ B753_RS0108855 reductase FabG: acyltransferase protein] 1-(5-phospho- - synthase: a 4-phosphooxy- CoA synthase: dehydrogenase: alanine D-glucopyranose D-glucopyranose a tRNA precursor a tRNA precursor with 3-oxoadipate 3-oxoadipate B753_RS0118340 B753_RS0110815 B753_RS0110815 B753_RS0112550 B753_RS0112550 [+ 4 isozymes] FAD synthetase: B753_RS0108855 PlsB: dehydratase B753_RS0117445 D-ribosyl)-AMP glutamate N- L-aspartyl- UDP-α-D-glucose L-quinate a 2,3,4-saturated a 1-stearoyl 2- B753_RS0111420 4-(glutathion- a (3R)-3-[+ 2 isozymes] asd B753_RS0100320 racemase: alr ammonium 6-phosphate 6-phosphate with a 5' extension a 5' extension and 3-oxoadipate enol- anthranilate enol-lactonase: phenyl-Coβ- [+ 4 isozymes] 2'-(5''-triphospho- [+ 4 isozymes] B753_RS0110870 a cis,cis-[+ 2 isozymes] B753_RS0106790 (2S,4S)-4- gln acetyltransferase/ [tRNA Asn ] glucose-6- trehalose-6- 1,2-diacyl-sn acyl-carrier protein acyl-sn-glycerol roseoflavin adenine hydroxyglutaryl- 1-oleoyl-sn a (2E,6Z)-FabZ: fabZ 3-dehydroquinate bifunctional and a long 3' trailer a short 3' extension lactonase: pcaD degradation pcaD quinate GMP adenosylcobamide acyl-carrier protein (5Z)- adenine α-D-ribosyl)-3'- S-yl)-fenclorim delta11,29-3- L-aspartate 4- hydroxy-2,3,4,5- amino-acid phosphate phosphate GTP ppGpp -glycerol 3- 3-phosphate acetyl-CoA acetyl-CoA hexanoyl-CoA dinucleotide [acp] methyl ester -glycerol 3- octadecadienoyl- phosphoribosyl- D-ala ribonuclease D: ribonuclease 3-oxoadipate enol- I (aerobic) dehydrogenase: 5'-phosphate tetradecenoyl-CoA dephospho-CoA oxo-C48:2-[acp] semialdehyde tetrahydrodipicolinate acetyltransferase Asp-tRNA(Asn) synthase: 3-oxoadipate phosphate [acp] 3-dehydroquinate AMP cyclohydrolase/ carbamoyl- isomerase: B753_RS0118485ribonuclease PH: P protein lactonase: pcaD B753_RS0114710 phosphate ArgJ: argJ N-acetyl-L- B753_RS0108930 dehydratase: aroQ homoserine phosphoribosyl- 4-hydroxy- phosphate synthase: /Glu-tRNA(Gln) B753_RS0111085 α,α-trehalose ribonuclease D: B753_RS0110970 component: anthranilate 3-dehydroquinate 3-oxoadipate dehydrogenase: ATP diphosphatase tetrahydrodipicolinate B753_RS0100945 ornithine amidotransferase: F6P B753_RS0118485 rnpA 3-oxoadipate anthranilate 1,2- type I 3- 6-phosphate 4-methylphenyl 1-cis-vaccenoyl- 1-myristoyl- 3-oxo-(9Z)- a guanine 34 a 3- a cis,cis- a 1-acyl-sn a (3R,9Z)-3- reductase: carB gatB nucleoside- dioxygenase: CoA-transferase: 3-dehydroquinate adenosylcobinamide- butanoyl-CoA acetyl-CoA glutathione RX a 3-oxoicosanoyl- dehydroquinate B753_RS0118615 HisIE: trehalose- a tRNA precursor with ribotide a palmitoleoyl-[acp] sn-glycerol- a myristoyl-[acp] sn-glycerol hexadecenoyl-CoA queuine oxodocosanoyl- delta15,27-3- -glycerol 3- hydroxy-octadec- B753_RS0102380 glutamine-- diphosphate kinase: bifunctional (p)ppGpp 3-oxoadipate antB antA B753_RS0115310 dehydratase: aroQ GDP in tRNA [acp] dehydratase: homoserine B753_RS0112335 B753_RS0100210 carbamoyl phosphate 3-phosphate 3-phosphate acetyl-CoA C- tRNA guanosine(34) acetyl-CoA C- glutathione S- [acp] hydroxyC46:2- phosphate 9-enoyl-[acp] L-ornithine fructose-6- phosphatase: synthetase/guanosine- a short 3' extension CoA-transferase: catechol B753_RS0115315 adenosylcobinamide- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 3-oxoacyl-ACP 3-oxoacyl-ACP 1-acyl-sn-glycerol- 3-hydroxyacyl- dehydrogenase: β (S)-2,3,4,5- B753_RS0111580 GDP a tRNA precursor type I 3- acyltransferase transferase: 3-oxoacyl-ACP B753_RS0114695 1-(5-phospho- -D-ribosyl)- phosphate phosphate otsB α 3',5'-bis(diphosphate) 3'- B753_RS0115310 GDP 3-phosphate 3-phosphate transglycosylase acyltransferase reductase FabG: reductase FabG: [acp] 3-phosphate [acyl-carrier- UDP- -D- pyrophosphokinase: with a 5' extension [+ 2 isozymes] dehydroquinate B753_RS0107365 5-[(5-phosphoribosylamino) tetrahydrodipicolinate an L-asparaginyl- pyrophosphohydrolase: ribazoletransferase: FadA: Tgt: FadA: B753_RS0118125 B753_RS0108855 B753_RS0108855 reductase FabG: acyltransferase: Asn transaminase α α galactose B753_RS0115315 dehydratase: acyltransferase: acyltransferase: protein] 3-dehydroshikimate methylideneamino]imidazole- 2,3,4,5- L-cysteine biosynthesis [tRNA ] , -trehalose B753_RS0103500 ribonuclease PH: ribonuclease D: B753_RS0112550 B753_RS0115640 B753_RS0112550 [+ 4 isozymes] B753_RS0108855 L-methionine biosynthesis III (isomerizing) biosynthesis B753_RS0107220 [+ 2 isozymes] 3-oxoadipyl-CoA B753_RS0114695 B753_RS0118340 B753_RS01108151-cis-vaccenoyl- B753_RS01108151,2-dimyristoyl- a (3R)-3-[+ 2 isozymes] a (3R)-3-[+ 2 isozymes] a 1-acyl-2-B753_RS0110815 dehydratase L-homoserine 4-carboxamide VI (from L-methionine) B753_RS0110970 B753_RS0118485 4-methylphenyl-Co a glutathione- shikimate tetrahydropyridine- : glmS ribonuclease: [+ 4 isozymes] a queuosine 34 [+ 4 isozymes] HX a cis,cis-[+ 2 isozymes] palmitoyl-sn FabZ: fabZ UDP-α-D-glucose bifunctional (p)ppGpp 3-oxoadipyl-CoA GMP β-adenosylcobamide 2-palmitoleoyl- acyl-carrier protein sn-glycerol (7Z)- guanine 3-oxohexanoyl- S-conjugate hydroxydocosanoyl- hydroxyicosanoyl- a (2E,9Z)- 1-(5-phosphoribosyl)-5- 2,6-dicarboxylate N- rnpA 3-oxoadipyl-CoA 3-dehydroshikimate acyl-carrier protein acetyl-CoA delta15,27-3- dehydrogenase: D-glucosamine synthetase/guanosine- sn-glycerol- 3-phosphate tetradecenoyl-CoA in tRNA CoA [acp] [acp] -glycerol 3- octadeca-2,9- homoserine kinase: [(5- phosphoribosylamino) succinyltransferase: superpathway of branched chain amino acid biosynthesis ornithine met UDP-glucose thiolase: pcaF 5'-phosphate oxo-C46:2-[acp] B753_RS0106885 L-homoserine 6-phosphate 3',5'-bis(diphosphate) 3'- 3-phosphate phosphate dienoyl-[acp] B753_RS0117725 methylideneamino]imidazole-4- dapD carbamoyltransferase: S-adenosylmethionine homoserine O- 4-epimerase 3-oxoadipyl-CoA [+ 2 isozymes] 3-dehydroshikimate phosphoglucosamine GalE: galE pyrophosphohydrolase: lipoprotein posttranslational dehydratase: shikimate carboxamide isomerase: hisA N-succinyl-2-amino- pyruvate argF synthase: acetyltransferase: thiolase: pcaF O-phospho- thr mutase: B753_RS0103500 modification succinyl-CoA a [glycine-cleavage a (7Z)-3-oxo- 6-ketopimelate B753_RS0113690 B753_RS0111710 UDP-glucose [+ 2 isozymes] B753_RS0114700 1-palmitoyl- (11Z)-3-oxo- 3-oxo-(11Z)- 3-oxo- (+)-7-epi- a 3- shikimate L-homoserine phosphoribulosylformimino- O-acetyl-L- B753_RS0108350 GDP an uncharged tRNA a cis- sn-glycerol H O acetyl-CoA DHAP SAM hydrogen sulfide 4-epimerase a [prolipoprotein]- SAM complex H protein] a sulfurated [sulfur carrier] a palmitoyl-[acp] sn-glycerol hexadecenoyl-CoA octadecenoyl-CoA palmitoyl-CoA jasmonoyl-CoA 2 oxodocosanoyl- hexadec-7- AICAR-phosphate acetolactate homoserine succinyl-CoA protocatechuate vaccenoyl-[acp] 3-phosphate dIDP kinase AroK: succinyldiaminopimelate threonine α-D-glucosamine N 6 -octanoyl-L-lysine 3-phosphate acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- acyl-CoA enoyl-[acp] threonine synthase: synthase: GalE: galE L-cysteine lipoyl glycerol-3- 1-acyl-sn-glycerol- [acp] 3-oxoacyl-ACP 3-oxoacyl-ACP acetyl-CoA C- glycerol-3- B753_RS0117450 transaminase: dapC ammonia- 1-phosphate UDP-α-D-galactose acyltransferase acyltransferase acyltransferase thioesterase: B753_RS0107360 B753_RS0111455 O-acetylhomoserine prolipoprotein synthase: lipA phosphate 1-O- 3-phosphate reductase FabG: reductase: acyltransferase phosphate nucleoside- imidazole glycerol lyase, FadA: FadA: FadA: B753_RS0109325 shikimate 3- N-succinyl-L,L-2,6- B753_RS0111460 sulfhydrylase: UDP-N- diacylglyceryl lipoyl acyltransferase acyltransferase: B753_RS0108855 B753_RS0118580 FadA: dehydrogenase diphosphate kinase: phosphate synthase: biosynthetic: B753_RS0117620 B753_RS0112550 B753_RS0112550 B753_RS0112550 [+ 5 isozymes] B753_RS0112550 (NAD(P)(+)): phosphate diaminopimelate L-citrulline acetylglucosamine α transferase: synthase: lipA a [glycine-cleavage PlsB: B753_RS0110815 a (3R)-3-[+ 2 isozymes] a (3R,7Z)-3-[+ 2 isozymes] B753_RS0111580 thr B753_RS0117680 (S)-2-acetolactate ilvA UDP- -D-glucose dipalmitoyl (+)-7-epi- bifunctional prephenate succinyl- SAH diphosphorylase/ B753_RS0111765 an unsulfurated B753_RS0106790 [+ 4 isozymes] [+ 4 isozymes] [+ 4 isozymes] [+ 5 isozymes] B753_RS0116700 B753_RS0117730 L-homocysteine biosynthesis I 5'-deoxyadenosine met complex H protein] 1-cis-vaccenoyl- acyl-carrier protein (9Z)- jasmonate hydroxydocosanoyl- hydroxy-hexadec- [+ 2 isozymes] argininosuccinate glucosamine-1- Inorganic Nutrient Metabolism [sulfur carrier] 6 phosphatidate acetyl-CoA acetyl-CoA acetoacetyl-CoA sn-glycerol dITP dehydrogenase/3- diaminopimelate ketol-acid a [prolipoprotein]- N -lipoyl-L-lysine acyl-carrier protein sn-glycerol- palmitoleoyl-CoA myristoyl-CoA acetyl-CoA [acp] 7-enoyl-[acp] threonine synthase: phosphate N- D-glucopyranose PRPP biosynthesis tetradecenoyl-CoA 3-phosphate phosphoshikimate 1- D-erythro- desuccinylase: reductoisomerase: (2Z)-2-aminobut- MTA/SAH methionine methionine S-1,2-diacyl-sn- 3-phosphate ammonia- AICAR B753_RS0102075 acetyltransferase: 6-phosphate carboxyvinyltransferase: imidazole-glycerol- B753_RS0102250 B753_RS0111450 2-enoate nucleosidase: synthase: synthase: phosphomannomutase/ glyceryl-L-cysteine dimethyl sulfide lyase, glmU D-ribose 5- selenate reduction assimilatory urea cycle B753_RS0116800 phosphate (2R)-2,3- L-arginino- B753_RS0109035 B753_RS0104760 B753_RS0109665 phosphoglucomutase: Metabolic Clusters degradation biosynthetic: α phosphate lipoprotein sulfate reduction III 1-cis-vaccenoyl- 3-oxo-(7Z)- 4-methyl-3- (3Z)-hex- a cis,cis-delta9,21- a (3R,5Z)-3- a (9Z)-3-oxo- 5-enolpyruvoyl- imidazoleglycerol- L,L-diaminopimelate dihydroxy-3- succinate MTA/SAH N-acetyl- -D- B753_RS0111095 ribose-phosphate II (oxidation) quinoxaline-2- a cis- a ferrocytochrome succinyl-CoA glutathione ilvA methionine methionine a palmitoyl-[acp] a malonyl-[acp] aryl-carrier protein sn-glycerol- stearoyl-CoA 3-hydroxyC40:2- hydroxy-tetradec- octadec-9- 3',5'-ADP shikimate 3- phosphate methylbutanoate nucleosidase: glucosamine pyrophosphokinase: signal peptidase: selenate b tetradecenoyl-CoA oxoadipate 3-en-1-ol IDP argininosuccinate arg carboxyl adenylate vaccenoyl-[acp] 5 [+ 2 isozymes] synthase: synthase: phosphomannomutase/ N-end rule pathway I (prokaryotic) B753_RS0110860 dimethyl sulfide sulfate 3-phosphate acyl-CoA acetyl-CoA C- 3-oxoadipate glutathione S- [acp] 3-oxoacyl-ACP 5-enoyl-[acp]3-oxoacyl-ACP enoyl-[acp]3-oxoacyl-ACP 3'(2'),5'- phosphate dehydratase HisB: diaminopimelate 2,3-dihydroxy- 2-iminobutanoate B753_RS0110880 1-phosphate B753_RS0108800 sulfate beta-ketoacyl-[acyl- acyl carrier protein: 1-acyl-sn-glycerol- (2Z)-2-aminobut- lyase: argH B753_RS0109665 B753_RS0104760 phosphoglucomutase: sulfate desaturase: acyltransferase CoA-transferase: transferase: reductase FabG: reductase: reductase: bisphosphate chorismate B753_RS0117675 epimerase: isovalerate UDP-N- PRPP leucyl/phenylalanyl- adenylyltransferase: carrier-protein] B753_RS0108850 3-phosphate nucleoside- 2-enoate S-ribosyl-L- α B753_RS0105260 an (S-diacyl- adenylyltransferase: B753_RS0116360 FadA: B753_RS0115310 B753_RS0118125 B753_RS0108855 B753_RS0118580 B753_RS0118580 nucleotidase CysQ: synthase: B753_RS0106030 dehydratase: acetylglucosamine -D-glucopyranose tRNA--protein a lipoprotein B753_RS0104600 synthase II: acyl carrier protein: acyltransferase: diphosphate kinase: imidazole acetol- arg homocysteine met sn-glyceryl) dimethyl sulfoxide B753_RS0104600 argininosuccinate B753_RS0112550 B753_RS0115315 [+ 4 isozymes] B753_RS0118100 B753_RS0118535 B753_RS0100150 diphosphorylase/ 1-phosphate transferase: signal peptide B753_RS0104605 ammonium B753_RS0108650 B753_RS0100050 B753_RS01108151,2-dicis- [+ 3 isozymes] 3-(glutathion-S a cis,cis-[+ 2 isozymes] a (5Z)-3-oxo-[+ 2 isozymes] a (3R,9Z)-3-[+ 2 isozymes] B753_RS0111580 phosphate meso-diaminopimelate a [protein] -L-cysteinyl- adenosine 5'- B753_RS0104605 lyase: argH a 3-oxooctadecanoyl- a quinoxaline-2- a ferricytochrome [+ 4 isozymes] [+ 2 isozymes] glucosamine-1- UTP--glucose- an N-terminal B753_RS0105325 acyl-carrier protein acyl-carrier protein vaccenoyl- oleoyl-CoA -yl)-hexan-1-ol delta9,21-3- tetradec-5- hydroxy-octadec- chorismate histidinol-phosphate 3-methyl-2- N-terminal L- [apolipoprotein] phosphoselenate APS [acp] AMP carboxyl-[aryl- b (5Z)- 4-methyl-3- AMP ITP 2-oxobutanoate phosphate N- 1-phosphate carbamoyl- phosphatidate 5 acetyl-CoA succinate oxo-C40:2-[acp] enoyl-[acp] 9-enoyl-[acp] oxobutanoate arginyl-[protein] leucyl-L-arginine carrier protein] dodecenoyl-CoA oxoadipyl-CoA 2-iminobutanoate transaminase: diaminopimelate acetyltransferase: uridylyltransferase: phosphoadenylyl- L-arginino- phosphate synthase: acetolactate L-ornithine B753_RS0110620 decarboxylase: lysA glmU sulfate reductase: succinate B753_RS0100945 anthranilate chorismate mutase: 2-isopropylmalate branched-chain L-homocysteine galU a peptide dimethyl sulfone L-histidinol synthase: S-adenosyl-L-methionine cycle II leucyl/phenylalanyl- an N-acyl-(S- B753_RS0102420 carB synthase: trpE B753_RS0109530 synthase: leuA UDP-N-acetyl- selenite undecaprenyl-diphospho-N an [amino group carrier protein]- a (7Z)-3- a [lipoyl-carrier lys amino acid B753_RS0111455 superpathway of L- UDP-α-D-glucose a long-chain a [protein] N-terminal- dihomo γ- 1-cis-vaccenoyl-sn- a [protein]-L- phosphate α tRNA--protein diacyl-sn-glyceryl) dimethyl sulfone a (3Z)-dec- octanoyl-CoA acetyl-CoA H O 6 -D-glucosamine carbamoyl γ α a malonyl-[acp] C-terminal-γ-(L-glutamate 5- 2 oxohexacos- transaminase: B753_RS0111460 threonine biosynthesis sulfite -acetylmuramoyl-L-alanyl- - UDP-N-acetyl- -D-glucosamine 2,3,4-saturated formyl-L-methionine linolenoyl-CoA glycerol-3-phosphate a malonyl-[acp] protein]-N -[(R) methionine (2S)-2- met transferase: -L-cysteinyl- monooxygenase phosphate 3-enoyl-[acp] semialdehyde-2-yl)-L-glutamate peptide acyl-CoA PRPP anthranilate prephenate 2-oxobutanoate B753_RS0115675 (S)-2-aceto-2- a [protein] ornithine D-glutamyl-L-lysyl- D-alanine undecaprenyldiphospho- fatty acidlong-chain-acyl- beta-ketoacyl-[acyl- N-acetyl-gamma- acetyl-CoA C- 1-acyl-sn-glycerol- beta-ketoacyl-[acyl- 7-enoyl-[acp]3-oxoacyl-ACP -dihydrolipoyl]- peptide- isopropylmalate S-adenosylmethionine an N-terminal B753_RS0105325 [lipoprotein] SfnG: sfnG argininosuccinate deformylase: def thioesterase: hydroxybutanoate oxaloacetate N-terminal L- carbamoyltransferase: muramoylpentapeptide beta-N- CoA synthetase: carrier-protein] glutamyl-phosphate acyltransferase 3-phosphate carrier-protein] reductase FabG: L-lysine dihydrolipoyl methionine synthase: L-lysyl-[protein] synthase: anthranilate acetolactate 3-isopropylmalate aspartate/ L-cystathionine leucyl-L-lysine methanesulfinate argF acetylglucosaminyltransferase: reductase: peptide FadA: B753_RS0109325 acyltransferase: B753_RS0108855 dehydrogenase: (S)-S-oxide ketol-acid methionine synthase: B753_RS0113690 B753_RS0102075 B753_RS0112080 synthase II: synthase II: phosphoribosyltransferase: trpD prephenate bifunctional prephenate synthase: histidinol dehydratase: val tyrosine/aromatic selenodiglutathione deformylase: B753_RS0112550 [+ 5 isozymes] B753_RS0110815 lpdA reductase: reductoisomerase: L-citrulline ditrans,octacis-undecaprenyldiphospho-murG [+ 4 isozymes] B753_RS0108650a (5Z)-3- an [amino group carrierB753_RS0114550 protein]- γ 1-cis-vaccenoyl- a 3- B753_RS0108650 a (3R,7Z)-3-[+ 2 isozymes] dehydratase: dehydrogenase/3- B753_RS0111455 leuD leuC aminotransferase: B753_RS0104760 hydrogen sulfide a long-chain B753_RS0113080 di-homo- - a [lipoyl-carrier msrA N-(5- L-proline biosynthesis I B753_RS0111450 Fatty Acid and Lipid Biosynthesis N 6 -L-threonylcarbamoyladenosine 37 UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- C-terminal-γ-(5-phospho- [+ 4 isozymes] 2-palmitoleoyl-sn- [+ 2 isozymes] a protein-L- B753_RS0116805 histidinol acyl-carrier protein oxododec- linolenate oxodocosanoyl- hydroxyhexacos- 6 phosphoribosyl) phosphoshikimate 1- B753_RS0111460 B753_RS0111125 methionine synthase: AMP diphosphate 2,3,4-saturated an N-terminal L- 3-oxodecanoyl- protein]-N - dehydrogenase: 2-isopropylmaleate (R)-2,3-dihydroxy- -modified tRNA biosynthesis L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine 5-enoyl-[acp] L-glutamyl)-L-glutamate formate glycerol-3-phosphate [acp] 7-enoyl-[acp] methionine- -anthranilate carboxyvinyltransferase: (S)-2-aceto-2- B753_RS0109665 2-aminoethylphosphonate fatty acyl CoA methionyl-[protein] CoA lipoyl-L-lysine 3-phenyl-2- hisD 3-methylpentanoate asp palmitate biosynthesis II (bacteria and plants) Respiration phosphate acquisition (S)-S-oxide B753_RS0116800 hydroxybutanoate glu superpathway of (Kdo) -lipid A biosynthesis gondoate biosynthesis (Kdo) -lipid A methanesulfonate degradation I phosphoribosylanthranilate 3-isopropylmalate cys 2 2 glutathioselenol oxopropanoate 2,3-dihydroxy-3- L-homocysteine SAM thr isomerase: B753_RS0115830 ketol-acid histidinal glutamate 5-kinase: dehydratase: (anaerobic) biosynthesis I (2-aminoethyl) 3-(4- aspartate kinase: a (3R)-3- methanesulfonate 2503 an [L-cysteine 2552 a protein-L- aspartate/ methylvalerate 2-oxoglutarate decarboxylation to succinyl-CoA threonylcarbamoyl- a phosphate adenine 32 3-oxopentanoyl- 3-oxo-(5Z)- uridine a (5Z)-3- a supercoiled 1-(2- hydroxyphenyl) reductoisomerase: B753_RS0105535 leuD leuC an acetoacetyl-[acp] α-Kdo-(2-> phosphonate 18-hydroxyoleate a (4Z)-hexadec- a cytosine palmitoyl-CoA H O L-2,4- γ-L-glutamyl hydro-lyase: B753_RS0115120 UDP-N-acetyl- hydroxytetradecanoyl- AMP synthase: monooxygenase: monoester 2-aminoethylphosphonate- a malonyl-[acp] desulfurase]-S- 2 oxotetracos- methionine- tyrosine/aromatic B753_RS0111450 histidinol α in 23S rRNA in tRNA CoA tetradecenoyl-CoA in 23S rRNA duplex DNA carboxyphenylamino) pyruvate (2R,3S)-3- α-D-glucosamine [acp] a malonyl-[acp] an oleoyl-[acp] 4)- -Kdo-(2- a [2-oxoglutarate ssuD acid phosphatase: 23S rRNA long-chain-acyl- 4-enoyl-[acp] sulfanyl-L-cysteine acyl-CoA diaminobutanoate replicative (R)-S-oxide aminotransferase: dehydrogenase: 5-phosphate B753_RS0100150 superpathway of L-serine 3-oxoacyl-ACP B753_RS0108880 taurine degradation IV -pyruvate beta-ketoacyl-[acyl- tRNA 2- acetyl-CoA C- acetyl-CoA C- ribosomal RNA diaminobutyrate- 5-enoyl-[acp]3-oxoacyl-ACP -1-deoxy-D-ribulose aspartate/ (R)-2,3-dihydroxy- isopropylmalate L-aspartyl- beta-ketoacyl-[acyl- >6)-lipid IVlauroyl dehydrogenase B753_RS0111225 peptide- B753_RS0111125 hisD (S)-3-methyl-2- and glycine biosynthesis I A threonylcarbamoyl- transaminase: phnW (adenine(2503)-C(2) CoA synthetase: thiocytidine(32) acyltransferase acyltransferase thioesterase: large subunit reductase FabG: DNA helicase: gamma-glutamyl- reductase FabG: 6 sulfite hydrogen selenide carrier-protein] -2-oxoglutarate methionine 5-phosphate tyrosine/aromatic 3-methylpentanoate 3-isopropylmalate 4-phosphate UDP-N- carrier-protein] acyltransferase: E2 protein] N phosphate phosphonoacetaldehyde )-methyltransferase B753_RS0112080 FadA: FadA: B753_RS0104965 methyltransferase B753_RS0116175 indole-3-glycerol- phosphate oxopentanoate B753_RS0108855 2-oxoglutarate AMP synthase: taurine synthase II: synthetase TtcA: transaminase: B753_RS0108855 (R)-S-oxide aminotransferase: 2,3-dihydroxy-3- dehydrogenase: 3-phospho-D-glycerate adenosylhomocysteinase: acetylglucosamine synthase II: B753_RS0111915 -lipoyl-L-lysine RlmN: rlmN [+ 4 isozymes] B753_RS0112550 B753_RS0112550 [+ 5 isozymes] E: B753_RS0100925 phosphate phe his reductase: branched-chain aspartate- [+ 2 isozymes] dehydrogenase B753_RS0113065 taurine B753_RS0108650a (6Z)-3- B753_RS0106190an [L-cysteine a 2'-O- B753_RS0101535 a (3R,5Z)-3-[+ 2 isozymes] helicase: reductase: B753_RS0111125 methylvalerate leuB phosphoglycerate B753_RS0117095 acyltransferase: B753_RS0108650 lauroyl (L-threonylcarbamoyl) phosphonoacetaldehyde a 2-methyladenine 2503 a 2-thiocytosine 32 semialdehyde 2-oxoglutarate E1 component: [+ 4 isozymes] [+ 4 isozymes] palmitate 2552 L-aspartate 4- B753_RS0107995 synthase: B753_RS0111620 amino acid a (3R)-3- D-ribulose 5-phosphate an (11Z)-3-oxo-icos-11-enoyl-[acp] adenylate dioxygenase: hydrolase: 5'-deoxyadenosine met 18-hydroxyoleoyl- acyl-carrier protein oxooctadec- desulfurase]- methyluridine hydroxytetracos- msrB hydro-lyase: (2S)-2-isopropyl- dehydrogenase: B753_RS0114235 acyltransferase: dehydrogenase B753_RS0102795 in 23S rRNA AMP diphosphate in tRNA (3Z)-dodec- semialdehyde a single a [protein]-L- B753_RS0102980 transaminase: dehydrogenase: SAH hydroxybutanoyl- 6 B753_RS0113265 CoA L-cysteine propanoyl-CoA acetyl-CoA acetyl-CoA in 23S rRNA tyr B753_RS0100150 L-glutamate-5- B753_RS0107110 α-Kdo-(2->4)-B753_RS0110255 N -L- B753_RS0101355 6-enoyl-[acp] 3-enoyl-CoA 5-enoyl-[acp] stranded DNA (1S,2R)-1- L-cysteine 3-oxosuccinate asd [acp] D-arabinose E1 component: 2-aminoacetaldehyde methionine semialdehyde B753_RS0115675 3-phosphooxypyruvate UDP-3-O-[(3R)-3- 3-oxoacyl-ACP α-Kdo-(2->6)- threonylcarbamoyladenine C-(indol-3- (S)-3-methyl-2- biosynthesis I 3-hydroxyacyl- 5-phosphate B753_RS0102795 acetaldehyde L-aspartate 4- hydroxymyristoyl]-N- reductase: (lauroyl)-lipid IV synthase: tsaD yl)glycerol oxopentanoate [acyl-carrier- isomerase: A [+ 3 isozymes]a [2-oxoglutarate a [2-oxoglutarate ile semialdehyde 3-phosphoserine/ acetyl-α-D-glucosamine B753_RS0118580 lipid A biosynthesis an N 6 -L- decaprenyl-diphospho-N- UDP-N-acetyl- a (7Z,10Z,13Z,16Z UDP-N-acetyl- a (6Z)-3- a (5Z)-3- 3-phosphate 3-oxo- a long-chain branched-chain phosphohydroxythreonine protein] B753_RS0110355 dehydrogenase dehydrogenase 37 7-hydroxylaurate a (7Z)-hexadec- an alkylated DNA H O α digallate ser 4-methyl-2- UDP-3-O-[3- [+ 2 isozymes] acyltransferase: threonylcarbamoyladenine acetylmuramoyl-pentapeptide α-D-glucosamine a malonyl-[acp] ,19Z)-3-oxodocosa- myristoyl-CoA fatty acyl-CoA 2 an arachidoyl-[acp] -D-glucosamine oxooctadec- oxododec- tryptophan homoserine 6 6 7-enoyl-[acp] a purine RS0108180 a purine amino acid serine aminotransferase: dehydratase aldehydo-D-arabinose hydroxymyristoyl] N- B753_RS0105920 E2 protein] N E2 protein] N -S- in tRNA undecaprenyldiphospho- long-chain-acyl- DNA-3- 7,10,13,16,19-pentaenoyl-[acp] acyl-CoA UDP-N- 6-enoyl-[acp] 5-enoyl-[acp] tannase/feruloyl S-adenosyl-L-methionine cycle I (S)-1-pyrroline- oxopentanoate dehydrogenase: a (3R,11Z)-3-hydroxy- beta-ketoacyl-[acyl- 3-oxoacyl-ACP acetyl-CoA C- 3-oxoacyl-ACP 3-oxoacyl-ACP synthase transaminase: acetyltransferase: B753_RS0105960 FabZ: fabZ 5-phosphate acetylglucosamine α-D-Kdo-(2->4) -dihydrolipoyl- succinyldihydrolipoyl- muramoylpentapeptide beta-N- CoA synthetase: methyladenine thioesterase: enoyl-[acyl-carrier- acetylglucosamine 5-carboxylate branched-chain B753_RS0118615 icos-11-enoyl-[acp] carrier-protein] reductase FabG: acyltransferase reductase FabG: reductase: esterase family subunit B753_RS0115675 -α-D-Kdo- L-lysine L-lysine acetyl-CoA acetylglucosaminyltransferase: protein] reductase: 2-epimerase (non- B753_RS0108540 a (2E)-but- deacetylase: B753_RS0112080 glycosylase: B753_RS0108855 FadA: B753_RS0104965 B753_RS0108855 B753_RS0118580 alpha/beta beta: trpB pyrroline-5- amino acid homoserine 3-hydroxyacyl-[acyl- synthase II: B753_RS0111500 hydrolyzing): SAM serine O- O-phospho-L-serine 2-enoyl-[acp] B753_RS0108295 (2->6)-lipid A murG [+ 4 isozymes] B753_RS0116050 B753_RS0112550 [+ 5 isozymes] hydrolase: Na + RS0100130 Na + [+ 2 isozymes] ile carboxylate transaminase: dehydrogenase: carrier-protein] decaprenyl-pyrophosphoryl- B753_RS0108650a (9Z)-3-oxo- a DNA containing a (3R,7Z,10Z,13[+Z,16 2 isozymes]Z a long-chain B753_RS0105500 a (3R,6Z)-3-[+ 2 isozymes] a (3R,5Z)-3-[+ 2 isozymes] acetyltransferase: UDP-3-O-(3- an alkylated [+ 4 isozymes] a (2E)-icos- B753_RS0114920 reductase: B753_RS0115675 B753_RS0107365 enoyl-[acyl-carrier- D-arabinofuranose UDP (N-acetylglucosamine)-N- 7-hydroxylauroyl- acyl-carrier protein octadec-9- an apurinic/ ,19Z)-3-hydroxydocosa- UDP-N-acetyl-α- hydroxyoctadec- hydroxydodec- cysE phosphoserine hydroxymyristoyl) dehydratase 2-oxoglutarate AMP diphosphate nucleobase fatty acid 2-enoyl-[acp] ser B753_RS0103345 protein] reductase: 5-phosphate Amine and Polyamine Degradation acetylmuramyl-(pentapeptide) CoA enoyl-[acp] apyrimidinic site 7,10,13,16,19-pentaenoyl-[acp] acetyl-CoA lauroyl-CoA D-mannosamine 6-enoyl-[acp] 5-enoyl-[acp] gallate indole S-adenosylmethionine O-acetyl-L-serine phosphatase SerB: serB -α-D-glucosamine FabZ: fabZ dehydrogenase leu L-homoserine B753_RS0111500 synthase: pyrroline-5- bifunctional phosphoserine 2-dehydro-3- UDP-3-O-(3- E1 component: a (2E,11Z)-icosa-2,11-dienoyl-[acp] fluoride RS0112140 fluoride tryptophan B753_RS0113690 cysteine carboxylate phosphatase/homoserine deoxyphosphooctonate hydroxymyristoyl) B753_RS0102795 superpathway of putrescine degradation I a butanoyl-[acp] ethanolamine utilization 6 synthase synthase A: cysK reductase: L-glutamate homoserine kinase: phosphotransferase aldolase: glucosamine N- phenylethylamine an N -L- 1-palmitoyl- a carboxy- a 3,5,7,9,11,13,15- uridine 2605 a (9Z)-3- 6-O-trans- L-glutamine dihydrolipoyllysine- 37 pristanate a cis- a 3-oxoacyl-CoA (S)-5-hydroxyisourate a cis-delta19-3- met SAH B753_RS0110415 B753_RS0117725 B753_RS0114625 acyltransferase: enoyl-[acyl-carrier- degradation threonylcarbamoyladenine sn-glycerol cys adenylated-[ThiS hepta-oxo- a lignoceroyl-[acp] oxooctacos- methoxy-mycolyl- subunit biosynthesis I cysteine biosynthesis III ThrH: B753_RS0102425 in 23S rRNA oxo-C38:1-[acp] beta-ketoacyl-[acyl- protein] reductase: residue ethanolamine putrescine in tRNA long-chain-acyl- vaccenoyl-[acp] 23S rRNA hydroxyisourate beta: trpB synthase CysM: lpxD 2-phenylethylamine 1-acyl-sn-glycerol-3-phosphate sulfur-carriercysteine protein] hexadecanoyl-[PKS-acp]aldo/keto reductase: acetyl-CoA C- 3-oxoacyl-ACP 9-enoyl-[acp]3-oxoacyl-ACP trehalose 6- MTA/SAH nucleosidase: O-phospho- carrier-protein] B753_RS0111500 succinyltransferase: tRNA enoyl-[acyl-carrier- hydrolase: uraH hemin RS0116855 hemin pro 2-oxoglutarate ser KDO-8P UDP-2-N,3-O-bis[(3R)- primary-amine CoA synthetase: 3-phosphate desulfurase: B753_RS0117830 acyltransferase pseudouridine(2605) reductase FabG: reductase FabG: phosphate tryptophan B753_RS0109035 glu B753_RS0103515 L-homoserine synthase II: B753_RS0102800 ethanolamine threonylcarbamoyladenosine protein] reductase: trehalose- methionine synthase: NADP-specific 3-hydroxytetradecanoyl]- oxidase: B753_RS0112080 acyltransferase: B753_RS0108530 aldo/keto reductase: FadA: synthase RluB: hydroxyisourate B753_RS0108855 B753_RS0108855 synthase MTA/SAH nucleosidase: glutamine B753_RS0108650 a gondoyl-[acp] ammonia-lyase: dehydratase: B753_RS0103595 B753_RS0111500 phosphatase: B753_RS0104760 3-deoxy-D-manno- α-D-glucosamine 4-aminobutanal 6 [+ 4 isozymes] B753_RS0112550 B753_RS0108895 hydrolase: uraH subunit cys glutamate threonine synthase: serine B753_RS0103950 a cyclic N -L- B753_RS0110815 a thiocarboxy- B753_RS0116510 2605 (S)-2-oxo-4- [+ 2 isozymes] [+ 2 isozymes] otsB B753_RS0110880 synthetase: B753_RS0108025 1-palmitoyl-2- AMP ala 9-hydroxy-3,5,7,11,13,15- a pseudouridine a (2E)-tetracos- a cis-delta19-3- a cis-delta9-3- trehalose- methionine synthase: dehydrogenase: hydroxymethyltransferase: glyA a 3-oxohexanoyl- octulosonate UDP-2,3- phenylacetaldehyde threonylcarbamoyladenosine [ThiS-Protein] [+ 4 isozymes] beta: trpB B753_RS0103130 B753_RS0107360 B753_RS0108030 gamma- acyl-carrier protein cis-vaccenoyl hexaoxohexadecanoyl- in 23S rRNA hydroxy-4-carboxy- hydroxyC38:1- hydroxyC28:1- chloride RS0110120 chloride [acp] 8-phosphate diacylglucosamine AMP diphosphate pristanoyl-CoA acetyl-CoA 2-enoyl-[acp] trans-methoxy- B753_RS0109665L-homocysteine S-ribosyl-L-homocysteine gln B753_RS0104470 37 in tRNA phosphatidate [PKS-acp] an acyl-CoA 5-ureidoimidazoline [acp] [acp] phosphatase: NAD-dependent aminobutyraldehyde mono-mycolate trp glu thr gly 3-oxoacyl-ACP diphosphatase: acetaldehyde phenylacetaldehyde dehydrogenase: reductase FabG: B753_RS0110350 B753_RS0108050 biotin-carboxyl carrier dehydrogenase: B753_RS0114845 B753_RS0108855 α-Kdo lipid X protein assembly adenosylcobinamide- 1-palmitoyl- a 2'- 3-oxo-(5Z)- (E)-2- 1,6-anhydro-N- L-cystine RS0101440 L-cystine B753_RS0103940 NAD(P)- 4-aminobutanoate α-ribazole a (5Z)-dodec- a cis-delta17-3- MEP [+ 2 isozymes] GDP sn-glycerol a myristoyl-[acp] deoxyribonucleoside [DNA] pimeloyl-CoA ala dodecenoyl-CoA methylcrotonoyl- acetyl-β-muramate a protein a (3R)-3- 3-deoxy-manno- lipid-A-disaccharide a [biotin carboxyl- dependent alcohol dGTP 5-enoyl-[acp] oxo-C36:1-[acp] phenylacetate adenosylcobinamide- 3-phosphate 1-acyl-sn-glycerol- 5'-triphosphate DNA polymerase III acetyl-CoA C- CoA anhydro-N- 3-oxoacyl-ACP 1-deoxy-D-xylulose- hydroxyhexanoyl- octulosonate synthase: carrier protein]-L-lysine dehydrogenase: deoxyguanosinetriphosphate 8-amino-7- enoyl-[acyl-carrier- acetyl-CoA GDP 3-phosphate subunit gamma/tau: acyltransferase enol-CoA hydratase: acetylmuramic reductase FabG: 5-phosphate Lon protease: Nucleoside and Nucleotide Biosynthesis [acp] cytidylyltransferase: B753_RS0118375 biotin--[acetyl-CoA- B753_RS0111315 triphosphohydrolase: oxononanoate protein] reductase: 2+ 2+ phenylacetate-- ribazoletransferase: B753_RS0109340 FadA: B753_RS0105775 acid kinase: B753_RS0108855 reductoisomerase: B753_RS0107645 Mo RS0118850 Mo carboxylase] ligase: phosphate NAD(P)- B753_RS0105800 acyltransferase: synthase: 3-hydroxyacyl- kdsB lipid A disaccharide CoA ligase: paaF B753_RS0118340 B753_RS0112550 B753_RS0111500 B753_RS0107725 B753_RS0114205 B753_RS0108970 acetyltransferase: dependent alcohol B753_RS01108151-palmitoyl- [+ 7 isozymes] B753_RS0108910 3-hydroxyisovaleryl- N-acetyl-D- a cis-delta17-3-[+ 2 isozymes] 1-deoxy-D- superpathway of pyrimidine [acyl-carrier- (E. coli) 2'-deoxyguanosine triphosphate 8-amino-7- [+ 4 isozymes] a (2E,5Z)-dodeca- superpathway of pyrimidine adenine and CMP-Kdo a [biotin carboxyl- acyl-carrier protein 2-myristoyl [DNA] coenzyme A CoA muramate 6- hydroxyC36:1- xylulose 5- a peptide Aromatic Compound Biosynthesis deoxyribonucleotides de novo biosynthesis superpathway of guanosine superpathway of protein] tetraacyldisaccharide phenylacetyl-CoA B753_RS0111660 dehydrogenase: GMP adenosylcobalamin oxononanoate (3Z)-dec-3- 3,5-dienoyl-[acp] nucleobases salvage adenosine salvage VI carrier protein]-N phosphatidate acetyl-CoA phosphate [acp] phosphate nucleotides de novo biosynthesis I adenosine nucleotides dehydratase 4'-kinase: B753_RS0100245 enoyl-CoA nitrate RS0114015 nitrate de novo biosynthesis I FabZ: fabZ 6 -biotinyl-L-lysine phenylacetyl- acetyl phosphate enterobactin biosynthesis gln hydrogencarbonate uracil B753_RS0113490 4-hydroxyphenylpyruvate uracil CoA 1,2- biosynthesis IMP adenosine a (2E)-hex- lipid IV epoxidase: ethanol (11Z)-(S)-3- IMP asp phosphoribosyltransferase: A acetate kinase: (5Z,8Z,11Z,14Z,17Z) chorismate carbamoyl- 2-enoyl-[acp] (2E)-hexadecenoate (1S,2R)-1-C-(indol-3- a (5Z)-tetradec- 1-aminocyclopropane- a 23S rRNA a glutaryl-[acp] a cis-delta15-3- paaK ser 1911/1915/1917 hydroxyhexadec- B753_RS0109130 adenosine kinase: a [biotin carboxyl- B753_RS0111655 yl)glycerol 3-phosphate a malonyl-[acp] -icosapentaenoyl-CoA uridine a behenoyl-[acp] thr a protein phosphate synthase: adenylosuccinate acyl-CoA synthetase: 5-enoyl-[acp] acyl-CoA 1-carboxylate 11-enoyl-CoA methyl ester oxo-C34:1-[acp] tyr IMP dehydrogenase: UMP B753_RS0114495 enoyl-[acyl-carrier- carrier-protein dimer]- 2-(1,2-epoxy-1,2- tryptophan synthase beta-ketoacyl-[acyl- 23S rRNA 3-oxoacyl-ACP isochorismate B753_RS0100945 carB synthase: 3-deoxy-D-manno- stearate biosynthesis 1-aminocyclopropane- enoyl-[acyl-carrier- enoyl-[acyl-carrier- threonine tail-specific aspartate/ protein] reductase: 6 dihydrophenyl) acetate B753_RS0100040 subunit beta: trpB thioesterase: pseudouridine(1911/ enol-CoA hydratase: reductase FabG: synthase: B753_RS0108345 B753_RS0115140 UMP kinase: AMP octulosonic acid II (bacteria and plants) N -biotinyl-L-lysine carrier-protein] 1-carboxylate protein] reductase: protein] reductase: ammonia-lyase, protease: tyrosine/aromatic adenylo-succinate B753_RS0111500 acetyl-CoA [+ 4 isozymes] tryptophan synthase B753_RS0109325 1915/1917) B753_RS0105775 B753_RS0108855 B753_RS0101855 carbamoyl phosphate asp B753_RS0114185 transferase: acetyl-CoA synthase II: deaminase: B753_RS0111500 B753_RS0111500 biosynthetic: ilvA B753_RS0111600 aminotransferase: guanine and guanosine salvage II acetyl-CoA 2-(1,2-epoxy-1,2- allantoin degradation subunit beta: trpB [+ 5 isozymes] synthase RluD: [+ 2 isozymes] cytidylate kinase: B753_RS0108385 a palmitoyl-[acp] carboxylase B753_RS0108650a (7Z)-3-oxo- (5Z,8Z,11Z,14Z,17Z) B753_RS0109085 (2E,11Z)-hexadec- a (2E)- a cis-delta15-3- [+ 2 isozymes] isochorismate 3-(4- B753_RS0111125 XMP adenylosuccinate a hexanoyl-[acp] carboxylase dihydrophenyl) to glyoxylate I AMP diphosphate (2E)-hexadecenoyl-CoA coenzyme A B753_RS0108755 a (2E)-docos- carboxyl transferase D-glyceraldehyde 3-phosphate trp acyl-carrier protein hexadec-7- 2-oxobutanoate 1911/ 2,11-dienoyl-CoA enoylglutaryl- hydroxyC34:1- a peptide hydroxyphenyl) lyase: B753_RS0113415 3-oxo-stearoyl- biotin acetyl-CoA -icosapentaenoate a pseudouridine 2-enoyl-[acp] 2-oxobutanoate aspartate enoyl-[acp] [acp] methyl ester [acp] 2,3-dihydro-2,3- GMP synthase: B753_RS0101600 beta-ketoacyl-[acyl- α-Kdo-(2->6)-lipid IV [acp] synthase: subunit beta: isomerase: 1915/1917 in 23S rRNA pyruvate UDP guanosine A carboxylase urea degradation I (S)-(+)-allantoin carbamoyltransferase: B753_RS0108650 B753_RS0115865 dihydroxybenzoate B753_RS0106735 carrier-protein] a 3-oxooctadecanoyl- subunit: accC B753_RS0101120 allantoinase PuuE: synthetase: B753_RS0115205 nucleoside-diphosphate synthase II: KDO transferase: [+ 2 isozymes] GMP synthase: AMP [acp] 2-oxepin-2(3H)- B753_RS0108195 (S)-3- a (2E,7Z)- B753_RS0118860 aspartate kinase: B753_RS0111580 B753_RS0108650 B753_RS0108385 a [carboxyl-carrier urea α-linolenate a malonyl-[acp] a (3Z)-dodec- glutathione monochlorobimane 3-phenyl-2- a pimeloyl-[acp] a cis-delta13-3- long chain B753_RS0108035 6 ylideneacetyl-CoA allantoate a malonyl-[acp] a malonyl-[acp] 3'-dephospho- tyr hydroxyhexanoyl- hexadeca-2,7- β-alanine carbamoyltransferase: α-Kdo-(2->4)-α- 3-oxoacyl-ACP protein dimer]-N - ATP oxo-C32:1-[acp] polyphosphate isochorismatase: UTP guanine a 3-oxooctanoyl- urea acyl-CoA synthetase: methyl ester 3-enoyl-[acp] glutathione S- CoA oxopropanoate CoA methyl ester B753_RS0115210 Kdo-(2->6)-lipid IV reductase FabG: carboxybiotinyl-L-lysine oxepin-CoA beta-ketoacyl-[acyl- beta-ketoacyl-[acyl- aspartate/ dienoyl-[acp] 3-oxoacyl-ACP polyphosphate adenylate kinase: A carboxylase: uca dephospho- 4-aminobutyrate- B753_RS0101820 GMP [acp] hydrolase: allantoicase: B753_RS0100040 transferase: enoyl-[acyl-carrier- enoyl-[acyl-carrier- kinase 1: ppk1 B753_RS0104490 CTP synthase: pyrG B753_RS0108855 carrier-protein] carrier-protein] CoA kinase: tyrosine/aromatic enol-CoA hydratase: reductase FabG: -2-oxoglutarate (2S,3S)-2,3-dihydroxy- xanthine B753_RS0101085 urea-1-carboxylate B753_RS0100630 [+ 4 isozymes] B753_RS0118125 protein] reductase: protein] reductase: 3-oxoacyl-ACP lauroyl [+ 2 isozymes] synthase II: synthase II: B753_RS0112445 aminotransferase: B753_RS0105775 B753_RS0108855 transaminase: polyphosphate 2,3-dihydrobenzoate phosphoribosyltransferase: 3-oxo-5,6- [+ 4 isozymes] B753_RS0111500 B753_RS0111500 N-carbamoyl-L-aspartate guanylate kinase: CTP reductase FabG: acyltransferase: a (3R)-3- allophanate B753_RS0108650 B753_RS0108650 B753_RS0111125 a (2E)- [+ 2 isozymes] gabT kinase 1: ppk1 (S)-ureidoglycolate AMP diphosphate α-linolenoyl-CoA a (5Z)-3-oxo- (glutathion- ADP coenzyme A + 3-(4- trans-hex-2- a cis-delta13-3- 2,3-dihydro-2,3- ADP B753_RS0117330 B753_RS0108855 B753_RS0111915 Kdo -(palmitoleoyl) hydroxyoctadecanoyl- didehydrosuberyl- a 3-oxoglutaryl- H a (7Z)-hexadec- long chain B753_RS0107210 2 phosphatidylethanolamine hydrolase: atzF acyl-carrier protein acyl-carrier protein tetradec-5- S-yl)-bimane phe hydroxyphenyl) enoyl-CoA enoylpimeloyl- hydroxyC32:1- 3-oxopropanoate dihydroxybenzoate hypoxanthine -lipid IV [acp] CoA semialdehyde [acp] methyl ester 7-enoyl-[acp] polyphosphate [EntB aryl- dihydroorotase: [+ 2 isozymes] lauroyl A allophanate ureidoglycolate enoyl-[acp] pyruvate [acp] methyl ester [acp] ribonucleoside- 3-hydroxyacyl- biosynthesis I 3-oxo-5,6- dehydrogenase: carrier protein] B753_RS0102065 phosphoribosyltransferase: hpt a (3R)-3- acyltransferase: hydrolase: lyase: GDP dehydrosuberyl- B753_RS0118855 diphosphate hydroxyoctanoyl- B753_RS0110255 [acyl-carrier- 4'-phosphopantetheinyl a CDP-diacylglycerol CoA semialdehyde B753_RS0110130 B753_RS0100625 6-O-trans-keto- [EntF L-seryl- (S)-dihydroorotate reductase: GMP [acp] protein] (6Z,9Z,12Z,15Z,18Z,21Z)-3- an S-(1-hydroxy- a guanine 966 transferase: ser (Kdo) -lipid CDP-diacylglycerol--serine a glutaryl-[acp] hydrogencarbonate H + long chain a cis-delta11-3- 2,3-dihydroxybenzoate carrier protein] B753_RS0109225 α 2 dehydratase dehydrogenase: a malonyl-[acp] a pimeloyl-[acp] ala MEP CTP 2-oxopropyl) a cerotoyl-[acp] asp mycolyl-trehalose 3-hydroxyacyl- -Kdo-(2->4)- carbamate glyoxylate oxotetracosahexaenoyl-CoA methyl ester polyphosphate in 16S rRNA oxo-C30:1-[acp] B753_RS0101850 A, cold adapted O-phosphatidyltransferase: B753_RS0101085 acetyl-CoA C- carbonic anhydrase: 2-C-methyl-D- -[protein]- 16S rRNA 6-phosphate 2,3- dihydroorotate nucleoside- ribonucleoside- B753_RS0109235 [acyl-carrier- α-Kdo-(2->6)- FabZ: fabZ beta-ketoacyl-[acyl- 8-amino-7- 3-oxoacyl-ACP aspartate/ holo-ACP synthase: holo-ACP synthase: pssA 3-oxo-5,6- acyltransferase FadA: B753_RS0104690 erythritol 4-phosphate L-cysteineprotein (guanine(966)-N(2) enoyl-[acyl-carrier- trehalose- dihydroxybenzoate- dehydrogenase diphosphate kinase: diphosphate protein] (lauroyl)-lipid IV a (2E)-octadec- a 3-sn-phosphatidyl- carrier-protein] oxononanoate exopolyphosphatase: ppx reductase FabG: tyrosine/aromatic B753_RS0111535 A didehydrosuberyl- B753_RS0112550 protein] reductase: phosphatase: B753_RS0111535 (quinone): B753_RS0111580 dADP dehydratase L-serine urea degradation II synthase II: synthase: carbonic anhydrase: cytidylyltransferase: deglycase HchA: )-methyltransferase B753_RS0108855 AMP ligase: entE reductase: lipid A biosynthesis 2-enoyl-[acp] CoA B753_RS0111500 aminotransferase: otsB B753_RS0114645 B753_RS0102475 2 RsmD: rsmD a holo-[EntB aryl- a holo-[EntF L- B753_RS0116680 B753_RS0109225 FabZ: fabZ acyltransferase: phosphatidylserine [+ 4 isozymes] B753_RS0108650 B753_RS0108910 B753_RS0101145 a [protein]- an N - a cis-delta11-3-[+ 2 isozymes] B753_RS0111125 trehalose- (2,3-dihydroxybenzoyl) (L-seryl)adenylate enoyl-[acyl-carrier- 3-oxo-5,6- (4Z,7Z,10Z,13Z,16Z,19Z) long chain 4-(cytidine 5'- (R)-lactate a (2E)-hexacos- xanthine and CO acetyl-CoA a 3-oxopimeloyl- 8-amino-7- H O CO 966 carrier protein] seryl-carrier protein] B753_RS0109235 nucleoside- B753_RS0105920 decarboxylase 2 4-aminobutanoate urea acyl-carrier protein acyl-carrier protein 2 2 diphospho)-2-C- L-cysteine methylguanine hydroxyC30:1- oxaloacetate trans-keto- adenylate orotate PRPP xanthosine salvage a (2E)-oct- protein] reductase: dehydrosuberyl- -docosahexaenoyl-CoA [acp] methyl ester polyphosphate 2-enoyl-[acp] GTP diphosphate kinase: α α proenzyme: psd degradation III urease: ureC oxononanoate in 16S rRNA [acp] mono-mycolate 2-enoyl-[acp] -D-Kdo-(2->4)- - B753_RS0111500 CoA methyl-D-erythritol B753_RS0111580 B753_RS0104540 orotate D-Kdo-(2->6)-lipid A an L-1- thiolase: pcaF enoyl-[acyl-carrier- 4-aminobutanoate ureA dGDP xanthosine a stearoyl-[acp] phosphatidylethanolamine phosphoribosyltransferase: protein] reductase: trans-2,3- (6Z,9Z,12Z,15Z,18Z)-3- 1-stearoyl- 3-benzyl-3,6-dihydroxy- an N 3 -methyladenine 6-trans-3-oxo- 4-hydroxy- (2E,9Z)- 3S-(4- a (2E,5Z)- 6-O-cis-methoxy- dATP long-chain fatty 4-aminobutyrate- ammonium glutathione a cis-delta21-3- roseoflavin a 2,3-dihydroxybenzoyl- B753_RS0108245 dehydroadipyl-coA an oleoyl-[acp] sn-glycerol 6-(hydroxymethyl) glutathione hydroxyphenyl) tetradeca-2,5- mycolyl-trehalose a seryl-[EntF L- B753_RS0111500 acid activation 4-aminobutanoate -2-oxoglutarate oxotetracosapentaenoyl-CoA in DNA tridecenoyl-CoA 2-nonenal hexadecenoyl-CoA oxo-C40:1-[acp] [EntB aryl- nucleoside- acetyl-CoA C- -diketopiperazine DNA-3- acetyl-CoA C- glutathione S- -3-hydroxy- bifunctional 6-phosphate seryl-carrier protein] enol-CoA hydratase: degradation I transaminase: 1-acyl-sn-glycerol-3-phosphate glutathione S- dienoyl-[acp] 3-oxoacyl-ACP carrier protein] orotidine 5'-phosphate diphosphate kinase: superpathway of 5-aminoimidazole xanthine an octanoyl-[acp] a long-chain acyltransferase FadA: methyladenine acyltransferase: transferase: enol-CoA hydratase: propanoyl-CoA enoyl-[acyl-carrier- riboflavin kinase/ trehalose- B753_RS0105775 gabT 3-phosphate transferase: reductase FabG: B753_RS0111580 ribonucleotide biosynthesis palmitoleate fatty acid succinate B753_RS0112550 glycosylase I: B753_RS0118720 B753_RS0118125 B753_RS0105775 enol-CoA hydratase: protein] reductase: FAD synthetase: phosphatase: acyl-CoA 4-aminobutanoate acyltransferase: B753_RS0118125 B753_RS0108855 xanthine biosynthesis I (from stearate (3S)- semialdehyde B753_RS0111500 B753_RS0110870 otsB orotidine-5'-phosphate beta-ketoacyl-[acyl- acyl-CoA hydrolysis 4-aminobutyrate- [+ 4 isozymes] [+ 4 isozymes] B753_RS0100250 [+ 4 isozymes] [+ 4 isozymes] (S)-3-hydroxy-(9Z) B753_RS0105775 trehalose- phosphoribosyltransferase: (5Z)-dodec-5-enoate) synthetase: hydroxyadipyl- B753_RS01108151-stearoyl-2- 3-benzyl-3,6 -bis(glutathione) 4-trans- (glutathion-S- a cis-delta21-3-[+ 2 isozymes] roseoflavin decarboxylase: dGTP PRPP carrier-protein] succinate- acetyl-CoA (4Z,7Z,10Z,13Z,16Z)- 3-methyladenine an apurinic site acetyl-CoA a (5Z)-tetradec- B753_RS0100040 long-chain-acyl- CoA -2-oxoglutarate acyl-carrier protein oleoyl-sn-glycerol - 6-(hydroxymethyl) yl)-4-hydroxy- -hexadecenoyl-CoA (E)-4- hydroxyC40:1- cis-methoxy- an N-(2,3- B753_RS0113395 amidophosphoribosyltransferase: B753_RS0117330 synthase II: a (5Z)-dodec- a 2,3,4-saturated semialdehyde docosapentaenoyl-CoA within DNA undecenoyl-CoA 5-enoyl-[acp] 5'-phosphate [+ 4 isozymes] CoA synthetase: 3-hydroxyadipyl-CoA transaminase: 3-phosphate -diketopiperazine 2-nonenal coumaroyl-CoA [acp] mono-mycolate dihydroxybenzoyl)- B753_RS0116670 B753_RS0108650 5-enoyl-[acp] a long-chain fatty acyl CoA dehydrogenase: UMP beta-ketoacyl-[acyl- B753_RS0112080 acyl-CoA dehydrogenase: gabT seryl-[EntF L-seryl- amidophosphoribosyltransferase: XMP fatty acyl-CoA succinate gabD a 3-oxodecanoyl- carrier-protein] thioesterase: B753_RS0101125 carrier protein] UMP kinase: B753_RS0106810 [+ 4 isozymes] semialdehyde 3-oxo-2-(cis-2'-pentenyl) 5-phospho-β- [acp] synthase II: B753_RS0104965 cob(I)yrinate a,c- 2,3,6- glutathione 6-cis, 3-oxo- (2E,11Z)- an insertion sequence pyridoxamine B753_RS0114185 NAD-dependent succinate Nucleoside and Nucleotide Degradation an acyl-[acyl- a malonyl-[acp] -cyclopentane-1-(3R- a protein with a (7Z)-3-B753_RS0108650 stearoyl-CoA 3-oxoadipyl-CoA ATP trichlorohydroquinone ATP tridecenoyl-CoA octadecenoyl-CoA element IS30 a malonyl-[acp] GTP 5'-phosphate D-ribosylamine 3-oxoacyl-ACP [+ 5 isozymes] diamide-[corrinoid carrier protein] 4'-phosphopantetheine a disulfide bond cytidylate kinase: inosine-5'-phosphate biosynthesis I CMP phosphorylation oxotetradec- a 2,3,4-saturated succinate- beta-ketoacyl-[acyl- glutathione S- acetyl-CoA C- hydroxybutanoyl)-CoA transposase: malonyl-[acyl- pyridoxine/ phosphoribosylamine- reductase FabG: adenosyltranferase]ATP:cob(I)alamin enol-CoA hydratase: protein-disulfide B753_RS0113415 7-enoyl-[acp] fatty acid 3-oxoadipyl- semialdehyde purine nucleotides degradation II (aerobic) carrier-protein] transferase: phosphopantetheine acyltransferase: enol-CoA hydratase: B753_RS0109285 pyridoxamine -glycine ligase: S-methyl-5'- reductase DsbD: carrier protein] O- enterobactin B753_RS0108855 3-oxoacyl-ACP CoA dehydrogenase: UTP and CTP dephosphorylation I adenosyltransferase: B753_RS0118125 adenylyltransferase: B753_RS0118720 B753_RS0105775 guanylate cyclase: UDP AIR B753_RS0116245 CMP synthase II: B753_RS0105775 [+ 3 isozymes] methyltransferase 5'-phosphate [+ 2 isozymes] gabD thioadenosine B753_RS0115820 [+ 4 isozymes] B753_RS0108735 [+ 4 isozymes] an insertion B753_RS0108215 B753_RS0118150 cytidylate kinase: reductase: thiolase: a [corrinoid adenosyl-cob(III) B753_RS0108650 2,6-dichloro-3- 3'-dephospho- 3-oxo-2-(cis-2'-pentenyl) (S)-3-hydroxy-(11Z) a protein with BioC: bioC oxidase: pdxH a (3R)-3- UTP degradation IV triphosphate 4-cis- 5-(carboxyamino)imidazole GAR B753_RS0113415 B753_RS0118580 pcaF [+ 2 isozymes] AMP CoA acetyl-CoA -cyclopentane-1-(E- -octadecenoyl-CoA sequence IS30 with a malonyl-[acp] hydroxydecanoyl- S-methyl-5'- adenosyltransferase] yrinate a,c-diamide acyl-carrier protein a 3-oxoacyl-[acp] (glutathion-S-yl) undecenoyl-CoA reduced L- cyclic-GMP PLP ribonucleotide synthase: CDP [+ 2 isozymes] [+ 2 isozymes] integrated transposon methyl ester thioadenosine -hydroquinone buta-2-enoyl)-CoA cysteine residues ribonucleoside- B753_RS0107900 phosphoribosylglycinamide phosphoribosylglycinamide [acp] a (3R,7Z)-3- succinate CTP synthase: pyrG MTA/SAH nucleoside- 3-hydroxyacyl- 5'-nucleotidase SurE: diphosphate reductase: formyltransferase: formyltransferase: hydroxytetradec- cis-vaccenate succinyl-CoA nucleosidase: diphosphate kinase: [acyl-carrier- B753_RS0101640 nucleoside- B753_RS0109225 N5-CAIR B753_RS0104375 B753_RS0105905 7-enoyl-[acp] biosynthesis CTP UMP B753_RS0109035 an L-1- lipid A 1-(2-aminoethyl 3-(4-hydroxyphenyl)- an N-terminal 5-cis, 7-trans-3-oxo- 3-oxo-2-(cis-2'-pentenyl) (2E,7Z)- 1-cis-vaccenoyl- B753_RS0111580 protein] bifunctional an L-phenylalanyl- an N-terminal an L-arginyl- stearoyl-CoA H O a nucleoside an aromatic histidinol diphosphate kinase: 3-sulfino-L- -cyclopentane-1-(3R- 2 sn-glycerol- B753_RS0109235 3-hydroxyacyl- MTA/SAH phosphatidylethanolamine diphosphate) (E. coli) [tRNA Phe ] 3-oxo-propanoyl-CoA Arg tetradecadienoyl-CoA hexadecenoyl-CoA diphosphate B753_RS0111580 5-(carboxyamino)imidazole FGAR dehydratase metallophosphatase/ 5'-nucleotidase SurE: arginyl-[protein] [tRNA ] acyl-CoA amino acid CTP [acyl-carrier- lipid A leucyl/phenylalanyl- acetyl-CoA C- alanyl-[protein]arginyl-tRNA- acetyl-CoA C- hydroxyhexanoyl)-CoA 3-phosphate1-acyl-sn-glycerol- aspartate/ histidinol FabZ: fabZ a palmitoleoyl-[acp] 5'-nucleotidase: B753_RS0101640 nucleosidase: enol-CoA hydratase: nucleoside- ribonucleotide mutase: purE protein] phosphoethanolamine tRNA--protein acyltransferase: protein transferase: acyltransferase: enol-CoA hydratase: thioesterase: 3-phosphate dehydrogenase: phosphoribosylformylglycinamidine beta-ketoacyl-[acyl- bifunctional B753_RS0110880 diphosphate kinase: tyrosine/aromatic dehydratase B753_RS0118870 CMP transferase: B753_RS0118720 B753_RS0118720 B753_RS0105775 B753_RS0105775 B753_RS0104965 dUDP asp synthase: B753_RS0105795 a (2E)-dec- carrier-protein] MTR transferase: an N-terminal L- B753_RS0105330 B753_RS0111580 acyltransferase: aminotransferase: hisD CAIR GMP metallophosphatase/ B753_RS0102560 [+ 4 isozymes] [+ 4 isozymes] [+ 5 isozymes] 2-enoyl-[acp] FabZ: fabZ synthase II: IMP 5'-nucleotidase SurE: B753_RS0105325 arginiyl-3-sulfino- a tRNA Arg 3-oxo-2-(cis-2'-pentenyl) (S)-3-hydroxy-(7Z) 1,2-dicis- B753_RS0110815 B753_RS0111125 a (2E,7Z)- adenosine 5'-nucleotidase: lipid A 1,4'-bis(2-aminoethyl L-phenylalanyl-L- (3Z,5E)-dodeca- a nucleoside an aromatic his gln nucleoside- a 1,2-diacyl-sn-glycerol Phe acetyl-CoA 4-hydroxybenzoyl-CoA acetyl-CoA -cyclopentane-1-(E- stearate FGAM enoyl-[acyl-carrier- an (11Z)-3-B753_RS0108650 5'-nucleotidase SurE: B753_RS0101640 B753_RS0118870 diphosphate) (E. coli) a tRNA L-alanyl-[protein] 3,5-dienoyl-CoA -hexadecenoyl-CoA triphosphate vaccenoyl- UTP diphosphate kinase: phosphoribosylaminoimidazolesuccinocarboxamide pyrimidine deoxyribonucleotide phosphorylation tetradeca-2,7- arginyl-[protein] hexa-2-enoyl)-CoA 2-oxo-acid protein] reductase: oxooctadec- B753_RS0101640 bifunctional phosphatidate B753_RS0111580 synthase: B753_RS0100310 dienoyl-[acp] adenosine deaminase: IMP dehydrogenase: phosphoribosylformylglycinamidine 11-enoyl-[acp] metallophosphatase/ uridine dTMP dCMP B753_RS0111500 enoyl-[acyl-carrier- B753_RS0109760 bifunctional B753_RS0108345 CTP synthase: pyrG dUTP cyclo-ligase: B753_RS0105900 3-oxoacyl-ACP 5'-nucleotidase: thymidylate kinase: cytidylate kinase: protein] reductase: adenosine deaminase: metallophosphatase/ an L-1- an (S)-2- an N-terminal dehydro(indole- 3-oxo-2-(cis-2'-pentenyl) D-firefly (7Z)- a 1-alkyl-sn a decanoyl-[acp] reductase FabG: an L-phenylalanyl- an N-terminal an L-arginyl- glutathione a peptide with a H O a [protein]- SAICAR B753_RS0118870 lipid A -cyclopentane-1-(3R- 2 -glycerol 3- nicotinamide dUTP diphosphatase: B753_RS0105685 B753_RS0113415 B753_RS0111500 B753_RS0115095 5'-nucleotidase: phosphatidylethanolamine Phe halocarboxylate Arg 3-sulfo-L- 3-yl)acetonitrile luciferyl-CoA hexadecenoyl-CoA L-histidine CTP AIR B753_RS0108855 XMP [tRNA ] L-lysyl-[protein] [tRNA ] leader sequence B753_RS0105265 dTDP dCDP B753_RS0118870 cytidine lipid A leucyl/phenylalanyl- haloacid alanyl-[protein]arginyl-tRNA- glutathione S- hydroxyoctanoyl)-CoA signal acyl-CoA acyl-CoA phosphate1-acyl-sn-glycerol- bifunctional adenylosuccinate lyase: beta-ketoacyl-[acyl- a (7Z)-tetradec- [+ 2 isozymes] histidine kinase: nucleoside triphosphate inosine phosphoethanolamine tRNA--protein dehalogenase: protein transferase: transferase: enol-CoA hydratase: peptidase thioesterase: dehydrogenase: 3-phosphate nicotinamidase/ B753_RS0101600 nucleoside- nucleoside- carrier-protein] 7-enoyl-[acp] a (3R,11Z)-3- 5'-nucleotidase SurE: B753_RS0107345 guanine and guanosine salvage transferase: B753_RS0118305 B753_RS0118125 B753_RS0105775 B753_RS0109325 B753_RS0110740 pyrazinamidase: pyrophosphohydrolase: diphosphate kinase: diphosphate kinase: synthase II: hydroxyoctadec- guanosine transferase: an N-terminal L- B753_RS0105330 I: lepB acyltransferase: beta-ketoacyl-[acyl- B753_RS0101640 B753_RS0102560 [+ 4 isozymes] [+ 4 isozymes] [+ 5 isozymes] [+ 18 isozymes] B753_RS0100325 a [protein]- CDP B753_RS0103490 B753_RS0111580 B753_RS0111580 11-enoyl-[acp] B753_RS0105325 arginiyl-3-sulfo- a tRNA Arg 3-oxo-2-(cis-2'-pentenyl) a leader sequence a peptide a 2-acyl-1-alkyl-B753_RS0110815 AICAR B753_RS0108650 carrier-protein] bifunctional lipid A 4'-(2-aminoethyl L-phenylalanyl- a (2R)-2- (glutathion-S-yl)(1H- (2E,7Z)- N-phospho- a 3- 3-hydroxyacyl- a 1,2-diacyl-sn-glycerol a tRNA Phe a halide anion L-alanyl-[protein] -cyclopentane-1-(E- D-firefly luciferin sn-glycerol nicotinate ribonucleoside- dUMP guanosine dTTP dCTP synthase II: metallophosphatase/ diphosphate) (E. coli) L-lysyl-[protein] hydroxy fatty acid indol-3-yl)acetonitrile hexadecenoyl-CoA L-histidine bifunctional oxododecanoyl- [acyl-carrier- pyrimidine deoxyribonucleotides octa-2-enoyl)-CoA 3-phosphate diphosphate reductase: B753_RS0108650 5'-nucleotidase: thymidylate phosphoribosylaminoimidazolecarboxamide [acp] protein] dephosphorylation B753_RS0109225 a (9Z)-3- B753_RS0118870 synthase: thyA formyltransferase/IMP dehydratase hypoxanthine nucleoside triphosphate B753_RS0109235 3-oxoacyl-ACP oxohexadec- a [pyruvate dehydrogenase 1-myristoyl- (2E,4E)- cyclohydrolase PurH: purH an L-1- 3-phenyl-2- 1-chloro-2,4- (2E,7Z)- a [protein]- dTMP reductase FabG: 9-enoyl-[acp] FabZ: fabZ guanine pyrophosphohydrolase: lipid A phytenate O-succinyl-L- glutathione 6 an acyl-CoA H O cis-vaccenoyl-CoA dinitrobenzene E2 protein] N -S- 2 sn-glycerol tetradeca-2,4- dCDP guanine a (2E,11Z)- xanthosine phosphatidylethanolamine homoserine oxopropanoate tetradecenoyl-CoA L-tyrosine B753_RS0108855 3-oxoacyl-ACP B753_RS0103490 acyl-CoA synthetase: glutathione S- acetyldihydrolipoyl-L-lysine acyl-CoA acyl-CoA 3-phosphate dienoyl-CoA thymidylate kinase: FAICAR octadeca-2,11- dCTP dCMP lipid A O-succinylhomoserine 1-acyl-sn-glycerol- tyrosine nucleoside- [+ 2 isozymes] reductase FabG: xanthine 4-hydroxyphenylpyruvate transferase: dihydrolipoamide enol-CoA hydratase: thioesterase: dehydrogenase: 2,4-dienoyl- B753_RS0105685 xanthine dienoyl-[acp] phosphoethanolamine B753_RS0100040 sulfhydrylase: 3-phosphate protein kinase: diphosphate kinase: a (3R)-3- B753_RS0108855 dehydrogenase: guanine dioxygenase: hppD acetyltransferase: B753_RS0105775 CoA reductase: bifunctional phosphoribosyltransferase: enoyl-[acyl-carrier- transferase: [+ 4 isozymes] B753_RS0118465 B753_RS0118125 B753_RS0109325 B753_RS0110740 acyltransferase: B753_RS0111015 dTDP hydroxydodecanoyl- [+ 2 isozymes] xdhA xdhB deaminase: guaD dUTP diphosphatase: B753_RS0108315 B753_RS0103850 B753_RS0111580 phosphoribosylaminoimidazolecarboxamide B753_RS0117330 B753_RS0102560 [+ 4 isozymes] [+ 5 isozymes] [+ 18 isozymes] B753_RS0110815 a [protein]- [acp] a (3R,9Z)-3- protein] reductase: lipid A 1-(2-aminoethyl succinate L-homocysteine (2-hydroxyphenyl) a [pyruvate dehydrogenase (S)-3-hydroxy-(7Z) 1,2-dimyristoyl- (3E)-tetradec- formyltransferase/IMP B753_RS0105265 diphosphate AMP phytenoyl-CoA 2,4-dinitrophenyl- 6 (2E,11Z)- L-tyrosine dCTP hypoxanthine 3-hydroxyacyl- B753_RS0111500 a 1,2-diacyl-sn-glycerol acetate E2 protein] N - -tetradecenoyl-CoA a carboxylate sn-glycerol nucleoside- cyclohydrolase PurH: purH hydroxyhexadec- nucleoside triphosphate diphosphate) (E. coli) S-glutathione octadecenoyl-CoA 3-enoyl-CoA phosphate phosphoribosyltransferase: hpt [acyl-carrier- xanthine dihydrolipoyl-L-lysine 3-phosphate diphosphate kinase: 9-enoyl-[acp] a cis- pyrophosphohydrolase: protein] B753_RS0111580 Secondary Metabolite Biosynthesis 3-hydroxyacyl- vaccenoyl-[acp] xanthine B753_RS0103490 IMP GMP dehydratase [acyl-carrier- dUTP dUMP dehydrogenase: (2E,9Z)- (7Z)- 1-palmitoyl- (S)-2-oxo-4- UDP phosphatidylglycerophosphate a very-long- (2E,6Z,9Z,12Z,15Z,18Z) an L-arginyl- glutathione methylmercury carbonic acid dTTP FabZ: fabZ protein] xdhA xdhB a protein sn-glycerol hydroxy-4-carboxy- acinetobactin biosynthesis (1-octadecenoyl(9Z), 2-palmitoyl) chain fatty acid -tetracosahexaenoyl-CoA [tRNA Arg ] GTP H O octadecenoyl-CoA tetradecenoyl-CoA ribonucleoside- preQ biosynthesis dehydratase long-chain-acyl- glutathione S- 2 carbonic anhydrase: acyl-CoA 3-phosphate 5-ureidoimidazoline 0 a (2E)-dodec- arginyl-tRNA- 1-acyl-sn-glycerol- FabZ: fabZ urate 5-hydroxy-CTP 5-hydroxy-CMP enol-CoA hydratase: GTPase ObgE: enol-CoA hydratase: OHCU diphosphate 2,3- 2-enoyl-[acp] phosphatidylglycerophosphatase CoA synthetase: protein transferase: transferase: B753_RS0104690 dehydrogenase: 3-phosphate a (2E,9Z)- cis-vaccenate B753_RS0105775 B753_RS0105540 B753_RS0105775 decarboxylase: reductase: dihydroxybenzoate thr A: B753_RS0100465 B753_RS0112080 B753_RS0105330 B753_RS0118125 carbonic anhydrase: B753_RS0110740 acyltransferase: peptidoglycan biosynthesis I (meso-diaminopimelate containing) Cell Structure Biosynthesis enoyl-[acyl-carrier- hexadeca-2,9- [+ 3 isozymes] uraD B753_RS0109225 GTP an N-terminal Arg [+ 4 isozymes] B753_RS0101145 [+ 18 isozymes] 2,3- protein] reductase: dienoyl-[acp] 1-oleoyl-2-palmitoyl- a very-long-chain (3S,6Z,9Z,12Z,15Z,18Z)-3- a tRNA (S)-3-hydroxy-(9Z) 1-palmitoyl-B753_RS0110815 B753_RS0109235 AMP diphosphate arginyl-[protein] methylmercury- phosphate GDP + (2E,7Z)- dihydroxybenzoate- GTP fatty acyl-CoA hydroxytetracosapentaenoyl-CoA H -octadecenoyl-CoA CO H O 2-myristoyl (S)-(+)-allantoin UDP-N-acetyl-α-D-glucosamine B753_RS0111500 enoyl-[acyl-carrier- phosphatidylglycerol S-glutatione 2 2 tetradecenoyl-CoA dUDP cyclohydrolase Entner-Doudoroff pathway I Carbohydrate Degradation phosphatidate AMP ligase: entE 7,8- protein] reductase: UDP-N-acetylglucosamine I FolE: folE D-galactose degradation I (Leloir pathway) (2,3- dihydroneopterin a dodecanoyl-[acp] B753_RS0111500 1-carboxyvinyltransferase: (L-threonyl) D-glucopyranose dihydroxybenzoyl) 3'-triphosphate β-D- (E)-1-(L-cystein-S-yl)-N- 1-palmitoyl- a [protein]- murA adenylate 6-phosphate UDP-N-acetyl-α-D-muramoyl- (2E,6Z,9Z,12Z,15Z,18Z,21Z) 4-trans-3-oxo- (2E,5Z)- (5Z)- dCDP adenylate a palmitoleoyl-[acp] galactopyranose D-alanyl-D-alanine 2-methylbutanoate ω a nucleoside lauroyl-CoA H O π 6-carboxytetrahydropterin L-alanyl-γ-D-glutamyl-L-lysine hydroxy- -(methylsulfanyl) 2 tetradecenoyl-CoA sn-glycerol N -phospho- UDP-N-acetyl-α-D- 2,3- beta-ketoacyl-[acyl- -tetracosaheptaenoyl-CoA undecenoyl-CoA triphosphate dodecenoyl-CoA ribonucleoside- synthase: galactose-1- UDP-N-acetylmuramoyl- acetate- heptan-1-imine acetyl-CoA C- acyl-CoA acyl-CoA 3-phosphate L-histidine glucosamine-enolpyruvate dihydroxybenzoate- carrier-protein] cystathionine nucleoside triphosphate 1-acyl-sn-glycerol- phosphohistidine diphosphate B753_RS0113440 epimerase: tripeptide--D-alanyl- -CoA enol-CoA hydratase: acyltransferase: enol-CoA hydratase: thioesterase: dehydrogenase: AMP ligase: entE synthase II: phosphatidylglycerol 6-phospho beta-lyase: pyrophosphohydrolase: 3-phosphate phosphatase: reductase: UDP-N-acetylmuramate 6-carboxy-5,6,7,8- laurate B753_RS0104800 D- alanine ligase: ligase: acs B753_RS0105775 B753_RS0118720 B753_RS0105775 B753_RS0104965 B753_RS0101365 a 2,3- an L-threonyl- B753_RS0108650 biosynthesis I (plastidic) D-glucono- B753_RS0106740 B753_RS0103490 acyltransferase: B753_RS0116695 B753_RS0109225 dehydrogenase: α-D- (E)-ω-(methylsulfanyl) [+ 4 isozymes] [+ 5 isozymes] [+ 18 isozymes] glu dihydroxybenzoyl- [L-threonyl- tetrahydropterin α B753_RS0117500 2-methylbutanoyl- (3S,6Z,9Z,12Z,15Z,18Z,21Z)-3- pyruvate (S)-3-hydroxy-(5Z) 1-palmitoyl-2-B753_RS0110815 B753_RS0109235 B753_RS0102910 long-chain-acyl- palmitoleate 1,5-lactone galactopyranose UDP-N-acetyl- -D-muramoyl-L-alanyl- AMP diphosphate heptyl-thiohydroximate 2-trans- a nucleoside 5'- (2E,5Z)- a [protein]- ala [aryl-carrier protein] carrier protein] 7-carboxy-7- CoA hydroxytetracosahexaenoyl-CoA acetyl-CoA -dodecenoyl-CoA laurate cis-vaccenoyl a 3-oxotetradecanoyl- CoA synthetase: DHAP γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine nonenoyl-CoA monophosphate tetradecenoyl-CoA L-histidine CDP UDP-N-acetyl-α-D-muramate phosphatidate glutamate deazaguanine [acp] B753_RS0112080 glycerol-3- racemase: murI 2,3-dihydroxybenzoyl-[aryl- synthase QueE: phosphate UDP-N-acetylmuramate- carrier protein]:L-threonyl- 3-oxoacyl-ACP [+ 4 isozymes] D-gluconate glutamate B753_RS0105740 dehydrogenase α-D-galactose UDP-α-D-glucose 2,3,5,6- (E)-1-(L-cystein-S-yl)-N- a [protein]-L- a cytidine 34 a [protein]- a [protein]- -L-alanine ligase: [peptidyl-carrier protein] 2,3- reductase FabG: 6-phosphate an L-arginyl- an N-terminal L- MoO - a D-aspartyl- τ racemase: murI 7-carboxy-7- lauroyl-CoA (NAD(P)(+)): 1-phosphate palmitoyl-CoA a ferrocytochrome b glutathione hydroxy-ω-(methylsulfanyl) 2-oxoadipate 2 2-phosphoglycolate ω N -phospho- L-tyrosine dihydroxybenzoyltransferase: B753_RS0108855 5 tetrachlorohydroquinone Arg molybdopterin ATP asp proline ( = 180) in tRNA B753_RS0108270 deazaguanine B753_RS0116700 phosphogluconate [tRNA ] glutamyl-[protein] [tRNA ] acyl-CoA desaturase: glutathione S- arginyl-tRNA- pentan-1-iminecystathionine 2-oxoglutarate cofactor D-aminoacyl- phosphoglycolate peptidyl-prolyl cis- tRNA (cytidine(34) L-histidine phosphate D-glt B753_RS0101810 [+ 2 isozymes] sn-glycerol dehydratase: molybdenum cofactor phosphohistidine protein tyrosine α 7-cyano-7- B753_RS0116360 transferase: protein transferase: beta-lyase: dehydrogenase tRNA deacylase: phosphatase: trans isomerase: -2'-O)- UDP-N-acetyl- -D-muramoyl-L-alanine a (3R)-3- 3-phosphate B753_RS0111645 guanylyltransferase: phosphatase: phosphatase: deazaguanine [+ 3 isozymes] B753_RS0118125 B753_RS0105330 E1 component: B753_RS0107525 B753_RS0107965 methyltransferase: a 2,3- hydroxytetradecanoyl- an N-terminal B753_RS0106740 B753_RS0100510 B753_RS0116695 B753_RS0115880 synthase glycerol-3- [+ 4 isozymes] (E)-ω-(methylsulfanyl) B753_RS0102795 adenylyl B753_RS0114045 [+ 2 isozymes] [+ 7 isozymes] B753_RS0102705 UDP-N-acetylmuramoyl- dihydroxybenzoyl-L- [acp] KDGP a ferricytochrome b palmitoleoyl-CoA L-arginiyl-L- a tRNA Arg pyruvate tRNA asp D-aspartate a 2'-O- a [protein]- a [protein]- QueC: queC phosphate 1-O- 5 2,3,5-trichloro-6-(glutathion- pentyl-thiohydroximate molybdenum a [protein]-L- threonyl-[L-threonyl- 3-hydroxyacyl- phosphatidylglycerol glucose and glucose-1-phosphate degradation glutaryl-CoA NADH CO glycolate methylcytidine 34 L-alanine--D- acyltransferase S-yl)-hydroquinone glutamyl-[protein] 2 cofactor proline (ω = 0) L-histidine L-tyrosine carrier protein] [acyl-carrier- biosynthesis II (non-plastidic) UDP- in tRNA glutamate ligase: peptidoglycan maturation (meso-diaminopimelate containing) preQ PlsB: α histamine 2,3- 0 protein] 2-dehydro-3-deoxy- -D- B753_RS0107395 B753_RS0106790 glucose 4- DHAP phosphogluconate glucopyranose lipid II (meso dihydroxybenzoyl-L- dehydratase a 1-acyl-sn epimerase α putative histamine glycerol-3- 1-phosphate 2-bromo-3-(4- (E)-1-(L-cystein-S-yl)-N- a dimer of non- (S)-3- a (2E,9Z)- a [protein]- 6-O-cis-keto- D-serine D-serine meso-diaminopimelate UDP-N-acetyl- -D-muramoyl- diaminopimelate containing) threonine cyclase: FabZ: fabZ aldolase: GalE: galE a sulfurated glutathione an L-arginyl- an N-terminal L- 2-hydroxyisobutyramide oleoyl-CoA H O oleoyl-CoA N-monooxygenase: -glycerol 3- SAM dethiobiotin hydroxy-ω-(methylsulfanyl) adjacent 2'- hydroxyhexadecanoyl- 2 octadeca-2,9- N-phospho- mycolyl-trehalose RS0114865 L-alanyl-D-glutamate B753_RS0101810 phosphate B753_RS0111640 nitrophenyl)propanoate Arg ν D-ala D-ala monofunctional phosphate [sulfur carrier] glutathione S- [tRNA ] aspartyl-[protein] h CoA acyl-CoA acyl-CoA 6-phosphate basC a (2E)-tetradec- dehydrogenase UDP- phosphomannomutase/ biotin arginyl-tRNA- nonan-1-iminecystathionine deoxycytidines dienoyl-[acp] L-histidine D-ala biosynthetic a 2,3-dihydroxybenzoylmethyloxazolinyl- 1-acyl-sn-glycerol- glucose 4- transferase: amidase: thioesterase: dehydrogenase: enoyl-[acyl-carrier- phosphohistidine trehalose- UDP-N-acetylmuramoyl- 2-enoyl-[acp] (NAD(P)(+)): phosphoglucomutase: synthase protein transferase: beta-lyase: in DNA deoxyribodipyrimidine enol-CoA hydratase: N-hydroxyhistamine myo-inositol 3-phosphate D-glyceraldehyde B753_RS0104000 protein] reductase: phosphatase: phosphatase: peptidoglycan [L-threonyl-carrier protein] B753_RS0116700 pyruvate epimerase B753_RS0111095 BioB: bioB B753_RS0118125 B753_RS0105330 photo-lyase: B753_RS0105775 B753_RS0104965 B753_RS0110740 D-alanine--D- L-alanyl-D-glutamate-- biosynthesis enoyl-[acyl-carrier- 3-phosphate D-glucopyranose an N-terminal B753_RS0106740 B753_RS0116695 otsB transglycosylase: sn-glycerol acyltransferase: GalE: galE an unsulfurated [+ 4 isozymes] (E)-ω-(methylsulfanyl) [+ 5 isozymes] [+ 18 isozymes] B753_RS0111500 2, 6-diaminopimelate protein] reductase: phosphomannomutase/ met 5'-deoxyadenosine biotin L-arginiyl-L- a tRNA Arg pyruvate a 2'-deoxycytidineB753_RS0105470 2-hydroxy-2- alanine ligase: mtgA D-glucopyranose B753_RS0110815 2-(glutathion-S-yl)-3-(4- nonyl-thiohydroximate (2E)- (2E,9Z)- a [protein]- trehalose-cis-keto- ligase: B753_RS0117505 pre-acinetobactin B753_RS0111500 3-phosphate phosphoglucomutase: Quinoprotein [sulfur carrier] bromide aspartyl-[protein] in DNA methylpropanoate oleate an oleoyl-[acp] B753_RS0108275 a nascent peptidoglycan 6-phosphate a 1,2-diacyl- nitrophenyl)propanoate hexadecenoyl-CoA octadecenoyl-CoA L-histidine mono-mycolate synthase: glycerol-3- B753_RS0105260 glucose α with (L-alanyl-γ-D-glutamyl- sn-glycerol D-alanyl-D-alanine UDP-N-acetyl- -D-muramoyl-L-alanyl- B753_RS0101770 a myristoyl-[acp] phosphate 1-O- dehydrogenase B: γ meso-2,6-diaminopimeloyl-D- 3-phosphate 13-DPG -D-glutamyl-meso-2,6-diaminopimelate acyltransferase D-glucopyranose B753_RS0114320 alanyl-D-alanine) pentapeptide Ins(3)P 3-oxo-2-(cis-2'-pentenyl)- (E)-1-(L-cystein-S-yl)-N- 2,3-bis-O- 3,22-dioxochol- 1-oleoyl-sn beta-ketoacyl-[acyl- PlsB: 6-phosphate isovalerate a [ThiI sulfur-carrier a D-tyrosyl- 2,2-dichloroacetate pre-acinetobactin quinoprotein an acetyl-[acp] a malonyl-[acp] hydroxy-ω-(methylsulfanyl) cys (geranylgeranyl) -glycerol 3- Ins(1)P D-serine UDP-N-acetylmuramoyl- carrier-protein] phosphoglycerate α-D- cyclopentane-1-(3-oxobutanoyl)-CoA CTP Tyr 4-en-24-oyl-CoA B753_RS0106790 UDP-α-D- acetyl-CoA C- protein]-L-cysteine [tRNA ] glutathione S- acetyl-CoA C- phosphate tripeptide--D-alanyl- inositol kinase: pgk glucopyranose glucose beta-ketoacyl-[acyl- acetate--CoA hexan-1-iminecystathionine cysteine -sn-glycerol D-aminoacyl- synthase II: a 1-acyl-sn a CDP- galactose 1-acyl-sn-glycerol- inositol D-serine D- alanine ligase: monophosphatase: dehydrogenase: acyltransferase: ligase: acs 1-phosphate CDP-archaeol transferase: acyltransferase: B753_RS0108650 -glycerol 3- diacylglycerol 3-phospho- 1-phosphate carrier-protein] synthase beta-lyase: desulfurase: tRNA deacylase: 3-phosphate monophosphatase: ammonia-lyase: a nascent peptidoglycan a nascent peptidoglycan a mature peptidoglycan with B753_RS0106865 fatty acid elongation -- saturated B753_RS0103790 B753_RS0118720 synthase: B753_RS0118125 B753_RS0118720 B753_RS0117500 phosphate CDP-diacylglycerol-- D-glycerate II: B753_RS0108650 B753_RS0106740 a [ThiI sulfur- B753_RS0108530 B753_RS0100510 acyltransferase: B753_RS0106865 γ γ a 3-oxohexadecanoyl- phosphomannomutase/ chitin degradation II (Vibrio) isovaleryl-CoA AMP diphosphate (E)-ω-(methylsulfanyl) B753_RS0104745 with (L-alanyl- -D-glutamyl- with D,D cross-links (meso- (L-alanyl- -D-glutamyl-meso- 1-acyl-sn-glycerol- D-glucono- [+ 4 isozymes] pyruvate B753_RS0114200 Tyr [+ 4 isozymes] [+ 4 isozymes] B753_RS0110815 α acinetobactin myo-inositol [acp] glycerol-3-phosphate 3- an acetoacetyl-[acp] acyl-carrier protein carrier protein]-S- ala unsaturated a tRNA D-tyrosine 3-oxo-4-pregnene- UDP-N-acetyl- -D-muramoyl-L- meso-2,6-diaminopimeloyl- diaminopimelate containing) 2,6-diaminopimeloyl-D-alanyl- phosphoglucomutase: 1,5-lactone acetyl-CoA (+)-7-epi-jasmonoyl-CoA hexyl-thiohydroximate glyoxylate dioleoyl myo-inositol pyruvate 3-phosphate phosphatidyltransferase: an acetoacetyl-[acp] sulfanyl-L-cysteine CDP-archaeol 20-carboxyl-CoA alanyl-γ-D-glutamyl-meso-2,6- di-trans,octa-cis-undecaprenyl phosphate D-alanine) tetrapeptide D-alanine) pentapeptide 3-oxoacyl-ACP B753_RS0111095 chitin phosphatidate acyltransferase: pgsA SMP-30/ diaminopimeloyl-D-alanyl-D-alanine phosphomannomutase/ reductase FabG: B753_RS0110815 1-(3-sn- 2-phospho- gluconolactonase/ L,D-transpeptidase: L,D-transpeptidase: B753_RS0108855 a 1,2-diacyl- D-glycerate phosphoglucomutase: β α a mature peptidoglycan phosphatidyl) LRE family protein: N-acetyl- -D-glucosamine- (E)-1-(L-cystein-S-yl)-N- 2-keto-D- 6-O- -mycolyl- B753_RS0102270 B753_RS0102270 [+ 2 isozymes] sn-glycerol B753_RS0105260 a pseudouridine 1915 in 23S rRNA ω an N-modified 4-guanidinobutyramide palmitoleoyl-CoA a DNA segment with D,D cross-links (meso- -sn-glycerol enolase: B753_RS0103695 an N-formyl-L-methionylaminoacyl-tRNA 1,6-anhydro-N- hydroxy- -(methylsulfanyl) L-cystathionine gluconate Ins(2)P trehalose 6- a nascent peptidoglycan with a mature peptidoglycan a (3R)-3- 3-phosphate a chitodextrin aminoacyl-[tRNA] a nascent peptidoglycan diaminopimelate containing) 3-phosphate B753_RS0114630 D-glucopyranose 23S rRNA acetyl-β-D-muramate octan-1-imine acyl-CoA 2,5- phosphate undecaprenyldiphospho- a nascent peptidoglycan (L-alanyl-γ-D-glutamyl-meso- with (L-alanyl-γ-D-glutamyl- hydroxyhexadecanoyl- a 3-oxoacyl-[acp] D-gluconate peptide deformylase: def beta-N- cystathionine peptidyl-tRNA cystathionine inositol γ (pseudouridine(1915)- amidase: dehydrogenase: didehydrogluconate recombinase: trehalose- N-acetylmuramoyl-L-alanyl- with L,D cross links (meso- with (L-alanyl- -D-glutamyl- phosphatidylglycerophosphatase phosphoenol 6-phosphate peptide deformylase: acetylhexosaminidase: beta-lyase: hydrolase: beta-lyase: monophosphatase: 2,6-diaminopimelate) tripeptide meso-2,6-diaminopimeloyl- [acp] N(3))-methyltransferase B753_RS0104000 B753_RS0110740 reductase DkgB: B753_RS0102660 phosphatase: γ-D-glutamyl-meso-2,6- diaminopimelate containing) meso-2,6-diaminopimeloyl- A: B753_RS0100465 B753_RS0113080 B753_RS0111605 B753_RS0106740 B753_RS0108810 B753_RS0106740 D-alanine) tetrapeptide 3-hydroxyacyl- pyruvate ω B753_RS0106865 otsB glycine) tetrapeptide a CDP- an L-1- RlmH: B753_RS0104455 1,6-anhydro-N- (E)- -(methylsulfanyl) an N-modified an uncharged [+ 18 isozymes] B753_RS0100225 a DNA segment diaminopimeloyl-D-alanyl-D-alanine [acyl-carrier- formate 3 1915 GlcNAc pyruvate pyruvate L-homocysteine α, α'-trehalose a L-methionylaminoacyl-tRNA an N -methylpseudouridine acetyl-β-muramate octyl-thiohydroximate amino acid tRNA 4-guanidinobutanoate (2E,9Z)- 2,5-didehydro- in reverse myo-inositol diacylglycerol phosphatidyl- a chitodextrin 6-α-mycolate undecaprenyldiphospho- a mature peptidoglycan with protein] 3-oxoacyl-ACP in 23S rRNA hexadecenoyl-CoA D-gluconate orientation CDP-diacylglycerol-- sn-glycerol muramoylpentapeptide beta-N- a mature peptidoglycan (L-alanyl-γ-D-glutamyl-meso- dehydratase reductase: glycerol-3-phosphate 3- acetylglucosaminyltransferase: with L,D cross-links (meso- 2,6-diaminopimelate) tripeptide a mature peptidoglycan FabZ: fabZ beta-ketoacyl-[acyl- B753_RS0118580 pyruvate murG diaminopimelate containing) with (L-alanyl-γ-D-glutamyl- phosphatidyltransferase: (E)-1-(L-cystein-S- (Z)-1-(L-cystein-S S-(4-oxo-2- (S)-3- 3-[(4'- a negatively L-gulono- propane-1,2,3- a (2E)-hexadec- carrier-protein] [+ 2 isozymes] Reactive Blue 5 cob(I)alamin- a D-aminoacyl- uroporphyrinogen-I meso-2,6-diaminopimeloyl- pgsA yl)-N-hydroxy-2-(1H- -yl)-N-hydroxy-2- methylpentan- hydroxybutanoyl- methylsulfanyl) supercoiled DNA 1,4-lactone 2-enoyl-[acp] synthase II: [corrinoid ATP [tRNA] tricarboxylate lipid II (meso diaminopimelate containing) 1-(3-sn- beta-N- dyp-type indol-3-yl)ethan-1-imine phenylethan-1-imine D-aminoacyl- 2-yl)-L-cysteinecystathionine CoA butyl]malate DNA SMP-30/ glycine) tetrapeptide B753_RS0108650 a (3R)-3- adenosyltranferase] cystathionine cystathionine uroporphyrinogen 3-isopropylmalate tricarballylate enoyl-[acyl-carrier- phosphatidyl) a 2,3,4-saturated acetylhexosaminidase: peroxidase: ATP:cob(I)alamin tRNA deacylase: beta-lyase: topoisomerase gluconolactonase/ hydroxyacyl-[acyl- beta-lyase: beta-lyase: decarboxylase: enol-CoA hydratase: dehydrogenase: dehydrogenase: protein] reductase: -sn-glycerol fatty acyl-[acp] N,N'- B753_RS0111605 N,N',N''- B753_RS0112960 adenosyltransferase: B753_RS0100510 B753_RS0106740 IV subunit B: parE LRE family protein: 3-hydroxyacyl-carrier protein] fructose degradation 3-[(4-amino-6-chloro- B753_RS0106740 B753_RS0106740 4-methyl-4- B753_RS0101865 B753_RS0105775 leuB cobZ 3-phosphate 2,2'-disulfonyl adenosylcob(III)B753_RS0115820 (E)-2-(1H-indol-3-yl)- (Z)-2-phenyl-1- an uncharged [+ 2 isozymes] B753_RS0103695 B753_RS0111500 [acyl-carrier- diacetylchitobiose triacetylchitotriose 1,3,5-triazin-2-yl) phthalate pyruvate pyruvate a D-amino acid pyruvate sulfanylpentan- β azobenzene triphosphate alamin-[corrinoid 1-thioacetohydroximate thioacetohydroximate tRNA coproporphyrinogen I 7-(methylsulfanyl) cis-aconitate phosphatidylglycerophosphatase protein] -D-fructofuranose beta-N- amino]benzenesulfonate 2-one crotonyl-CoA a relaxed DNA L-gulonate a palmitoyl-[acp] adenosyltranferase] -2-oxoheptanoate A: B753_RS0100465 dehydratase 1-phosphate acetylhexosaminidase: 1-phosphofructokinase: an L-1- FabZ: fabZ B753_RS0111605 β pfkB phosphatidyl- -D-fructose 1,6- N-acetyl-D- 34 a dimer of adjacent a double-stranded 3-[(3'- (5Z)- an N 10 - an L-methionyl- a 5-carboxymethylaminomethyluridine S-fenclorimyl- an unsulfurated a phosphate Leu ν 2E)-tetradec-2-enoyl-CoA acetamide sn-glycerol bisphosphate glucosamine Met thymidine and 2'- h cys H O diphosphate oligonucleotide methylsulfanyl) dodecenoyl-CoA formyltetrahydrofolate [initiator tRNA ] in tRNA L-cysteine [sulfur carrier] 2 monoester methionyl-tRNA tRNA (cytidine(34) deoxycytidine in DNA cysteine inorganic propyl]malate acyl-CoA palmitate deoxyribodipyrimidine cystathionine enol-CoA hydratase: oligoribonuclease: 3-isopropylmalate alkaline amidase: a trans-2- Amino Acid Degradation formyltransferase: -2'-O)- desulfurase: diphosphatase: dehydrogenase: a 2,3,4-saturated enoyl-[acyl-carrier- photo-lyase: beta-lyase: B753_RS0105775 B753_RS0111510 dehydrogenase: phosphatase: B753_RS0104000 enoyl-[acyl- B753_RS0100145 methyltransferase: B753_RS0108530 B753_RS0106385 B753_RS0110740 long-chain-acyl- fatty acyl-[acp] protein] reductase: an N-formyl- B753_RS0105470 B753_RS0106740 leuB B753_RS0100895 carrier protein] B753_RS0102705 adjacent thymidine-2'- 6-chloro-2-phenyl- a sulfurated + [+ 18 isozymes] CoA synthetase: B753_RS0111500 L-valine degradation I L-leucine degradation I L-isoleucine degradation I L-arginine degradation L-methionyl- a tetrahydrofolate pyruvate (S)-3- ala phosphate H a nucleoside 5'- 6-(methylsulfanyl) L-threonine degradation I a 5-carboxymethylaminomethyl- deoxycytidine in DNA 4-sulfanylpyrimidine [sulfur carrier] (2E,5Z)- an alcohol acetate B753_RS0112080 [initiator tRNA met ] hydroxytetradecanoyl-CoA monophosphate II (AST pathway) 2'-O-methyluridine 34 in tRNA Leu -2-oxohexanoate dodecenoyl-CoA [+ 4 isozymes] enoyl-[acyl-carrier- val leu ile protein] reductase: thr arg palmitoyl-CoA branched-chain branched-chain a dimer of adjacent a dimer of (E)-1-(L-cystein-S- a double RNase G 3-[(6'- an organic B753_RS0111500 branched-chain threonine arginine N- ferulate ν ν an S-alkyl- malonate (S)-malate amino acid amino acid 2'-deoxycytidine and h non-adjacent h yl)-N-hydroxy-2-(4- stranded DNA degradation methylsulfanyl) hydroperoxide amino acid ammonia- succinyltransferase: ATP cob(II)inamide L-cysteine transaminase: feruloyl-CoA synthase: thymidine in DNA thymidines in DNA hydroxyphenyl)ethan-1-imine substrate mRNA hexyl]malate biotin-independent transaminase: lyase, deoxyribodipyrimidine deoxyribodipyrimidine cystathionine exo: recD cystathionine peroxiredoxin: malate:quinone transaminase: B753_RS0115675 B753_RS0107010 ATP:cob(I)alamin 3-isopropylmalate malonate 4-methyl-2-B753_RS0115675 (S)-3-methyl-2- B753_RS0114945 photo-lyase: photo-lyase: beta-lyase: B753_RS0112290 beta-lyase: ribonuclease G: B753_RS0110570 oxidoreductase: B753_RS0115675 biosynthetic: arginine N- adenosyltransferase: dehydrogenase: decarboxylase: mdcE oxopentanoate oxopentanoate B753_RS0105470 B753_RS0105470 (Z)-N-hydroxy-2-B753_RS0106740 B753_RS0112295 B753_RS0106740 B753_RS0102405 [+ 3 isozymes] mqo 3-methyl-2- ilvA succinyltransferase: trans-feruloyl-CoA B753_RS0115820 adjacent 2'-deoxycytidine- leuB B753_RS0111410 diphosphate AMP a thymidine in DNA pyruvate an alkyl-thiol [+ 2 isozymes] pyruvate (4-hydroxyphenyl) a 5'-phosphooligonucleotide 9-(methylsulfanyl) an alcohol oxaloacetate oxobutanoate (2Z)-2-aminobut- 2 astA triphosphate adenosylcobinamide thymidine in DNA an mRNA fragment acetate N -succinyl- acetimidothioate -2-oxononanoate 2-enoate L-arginine isovaleryl-CoA 2-methylbutanoyl-CoA N-succinylarginine a dimer of non-adjacent a dimer of non- 3-[(5'- dihydrolase: astB (2E,6E)-farnesyl a 5' triphospho- γ-L-glutamyl- isobutanoyl-CoA ν adjacent pyrimidine hν protoheme 4-hydroxybenzoate methylsulfanyl) L-cysteate ethanol 7,8-dihydropterin isovaleryl-CoA 2'-deoxycytidine and h ATP a ribonucleic acid diphosphate L-djenkolate [mRNA] gly N 2 -succinyl- D-alanine dehydrogenase: 2-iminobutanoate thymidine in DNA deoxyribodipyrimidine nucleosides in DNA deoxyribodipyrimidine protoheme IX cystathionine RNA glutathione 4-hydroxybenzoate pentyl]malate aspartate/ catalase: guanine L-ornithine polynucleotide 3-isopropylmalate B753_RS0115375 photo-lyase: photo-lyase: farnesyltransferase: beta-lyase: pyrophosphohydrolase: synthase: 3-monooxygenase: tyrosine/aromatic B753_RS0113155 deaminase: (E)-2- succinylornithine adenylyltransferase dehydrogenase: aminotransferase: 3-methylcrotonyl- B753_RS0105470 B753_RS0105470 B753_RS0116155 B753_RS0106740 B753_RS0112025 B753_RS0108260 pobA [+ 2 isozymes] guaD methylcrotonoyl-CoA transaminase: a 2'-deoxycytidine PcnB: B753_RS0103480 a pyrimidine S-(sulfanylmethyl) leuB B753_RS0111125 CoA ferroheme o a 5'-phospho- norophthalmate 7,8- methylacrylyl-CoA a thymidine in DNA a ribonucleic acid pyruvate protocatechuate 8-(methylsulfanyl) acetaldehyde enol-CoA hydratase: B753_RS0107015 in DNA nucleoside in DNA -L-cysteine [mRNA] 3-sulfopyruvate dihydrolumazine acetyl/propionyl/ 2 -2-oxooctanoate 2-oxobutanoate B753_RS0105775 N -succinyl- enol-CoA hydratase: methylcrotonyl- L-glutamate 5- B753_RS0105775 CoA carboxylase: (2S,3S)-3-hydroxy-2- semialdehyde a dimer of non-adjacent a dimer of adjacent 2-trans, 4-trans dCTP (S)-3-hydroxy- B753_RS0115360 methylbutanoyl-CoA a lipid II uroporphyrinogen-III wound RNA [DNA] MeOH succinylglutamate- thymidine and 2'- hν pyrimidine hν VibB coenzyme A a peptide S-ethyl-L-cysteine -undecadienoyl- isobutanoyl-CoA B753_RS0115370 semialdehyde D-Ala-D-Ala CoA deoxycytidine propanoyl-CoA deoxycytidine in DNA deoxyribodipyrimidine nucleosides in DNA deoxyribodipyrimidine Xaa-Pro uroporphyrinogen-III cystathionine ATP-dependent DNA polymerase catalase: acetyl/propionyl/ dehydrogenase: carboxypeptidase: holo-ACP synthase: 2,4-dienoyl- triphosphate photo-lyase: photo-lyase: B753_RS0111535 aminopeptidase: C-methyltransferase: beta-lyase: RNA helicase RhlB: III subunit epsilon: B753_RS0113155 deaminase: methylcrotonyl- phosphate astD B753_RS0109920 CoA reductase: 2-methylacetoacetyl-CoA B753_RS0105470 a N-acetylglucosamine--N- B753_RS0105470 a holo-[VibB aryl- B753_RS0101940 cobA B753_RS0106740 B753_RS0116715 B753_RS0102015 [+ 2 isozymes] B753_RS0109020 CoA carboxylase propionyltransferase: N 2 - a 2'-deoxycytidine two adjacent pyrimidine 3',5'-ADP a proteinogenic B753_RS0103850 (S)-3-hydroxy- a thymidine in DNA D-ala acetylmuramyl-(tetrapeptide) carrier protein] a peptide pyruvate ethanethiol a nucleoside 5'- subunit alpha: succinylglutamate in DNA nucleosides in DNA precorrin-2 an unwound RNA (3E)-undec- formaldehyde dUTP isobutanoate B753_RS0111660 acetyl-CoA C- amino acid monophosphate B753_RS0110750 pyrophosphoryl-undecaprenol 3-enoyl-CoA propanoyl acyltransferase: succinylglutamate 3-methylglutaconyl- phosphate B753_RS0118720 desuccinylase: astE CoA [+ 4 isozymes] RNase III mRNA S-(4-hydroxy- 2-trans, 4-cis- an (R)-2- S-benzyl- 3-[(7'-methylsulfanyl) CTP (S)-methylmalonate- acetate kinase: DL-allothreonine O-acetyl-L-serine hydrogen selenide processing 2-methylpentan- a cis-2-enoyl-CoA a folate undecadienoyl- propionamide glu halocarboxylate L-cysteine heptyl]malate deoxycytidine semialdehyde B753_RS0111655 propanoyl-CoA acetyl-CoA substrate HAD family 2-yl)-L-cysteine CoA cysteine cystathionine cystathionine 3-isopropylmalate dihydrofolate triphosphate serine ribonuclease 3: hydrolase: enol-CoA hydratase: 2,4-dienoyl- amidase: synthase CysM: beta-lyase: beta-lyase: dehydrogenase: reductase: propanoate hydroxymethyltransferase: glyA B753_RS0105645 B753_RS0105775 CoA reductase: B753_RS0104000 deaminase: 4-aminobutyrate methylmalonate- HMG-CoA B753_RS0103515 RNase III B753_RS0109825 leuB B753_RS0111785 a (2R)-2- B753_RS0106740 B753_RS0106740 B753_RS0103850 B753_RS0109020 aminotransferase, semialdehyde gly acetaldehyde an mRNA fragment processing a halide anion 4-methyl-4- acetate L-selenocysteine pyruvate a 2,3,4-saturated (3R pyruvate benzyl thiol 10-(methylsulfanyl) (3E)-undec- UTP mitochondrial: gabT dehydrogenase hydroxymethylglutaryl- product mRNA hydroxy fatty acid sulfanylpentan-2-ol a 7,8-dihydrofolate propanoate L-proline degradation )-3-hydroxyacyl-CoA -2-oxodecanoate 3-enoyl-CoA (CoA acylating) CoA lyase: L-tryptophan degradation to B753_RS0115355 2-amino-3-carboxymuconate (S)-3-amino-2- : mmsA semialdehyde pro ω methylpropanoate methylmalonate- hydroxymethylglutaryl- an N-acetyl-β- an N -(1-hydroxy-2- S-(6-hydroxy- an adenosine 34 dCMP indolylmethylisothiocyanate glutathione a D-tryptophanyl- O-ureido-L- an L-cysteinyl- CoA lyase: isobutanoate Arg2 3-ethylmalate semialdehyde trifunctional D-hexosaminide oxopropyl)-[protein]-L-arginine 4-methylhexan- Trp asp in [tRNA ] Cys trp beta-N- [tRNA ] homoserine [tRNA ] biotin ATP deoxycytidylate dehydrogenase B753_RS0101225 transcriptional glutathione S-transferase: acetate--CoA protein 4-yl)-L-cysteinecystathionine D-aminoacyl- argininosuccinate tRNA adenosine(34) peptidyl-tRNA 3-isopropylmalate acetylhexosaminidase: deaminase: (CoA acylating) regulator/proline B753_RS0118125 ligase: acs deglycase HchA: beta-lyase: tRNA deacylase: synthase: deaminase TadA: hydrolase: biotin--[acetyl-CoA- dehydrogenase: acetoacetate B753_RS0111605 B753_RS0109630 : mmsA N-Formyl-L- dehydrogenase/L- [+ 4 isozymes] B753_RS0102475 B753_RS0106740 B753_RS0100510 B753_RS0102075 B753_RS0113425 B753_RS0108810 carboxylase] ligase: leuB an N-acetyl-β- dUMP isobutanoyl-CoA AMP diphosphate 3-methyl-3- 34 B753_RS0108970 kynurenine glutamate gamma- indol-3-ylmethylisothiocyanate-glutathione an alcohol (R)-lactate a [protein]-L-arginine pyruvate a tRNA Trp D-tryptophan canavaninosuccinate an inosine a tRNA Cys cys biotinyl-5'- D-hexosamine sulfanylhexan-1-ol 2-oxovalerate semialdehyde in [tRNA Arg2 ] adenylate hydrogencarbonate dehydrogenase: putA L-tyrosine degradation I (S)-1-pyrroline- (E)-1-(L-cystein-S-yl)-N-hydroxy- 5,10-methylene- 3-methyl-2- a 5-L-glutamyl- an (R)-2- L-selenocystathionine a protein with an organic a double L-kynurenine 5-carboxylate an amino acid ω felinine glutathione a glycyl-[tRNA Ala ] meso-tartrate tetrahydromethanopterin oxobutanoate [peptide] halocarboxylate -(methylsulfanyl)butan-1-imine a disulfide bond hydroperoxide stranded DNA 3-methyl-2-oxobutanoate HAD family cystathionine cystathionine tyr gamma- cystathionine glutaredoxin alkyl hydroperoxide D-aminoacyl- DNA gyrase tartrate L-histidine degradation I hydroxymethyltransferase: hydrolase: beta-lyase: beta-lyase: aspartate/ glutamyltransferase: ggt beta-lyase: 3: grxC reductase subunit F: tRNA deacylase: subunit A: dehydrogenase: panB an α-(5-L- B753_RS0109825 B753_RS0106740 B753_RS0106740 a protein with tyrosine/aromatic ω B753_RS0106740 B753_RS0100095 B753_RS0100510 B753_RS0106005 B753_RS0108710 L-glutamate-5- a peptide glutamyl)- an (S)-2- (E)- -(methylsulfanyl) 3-methyl-3- seleno-L- reduced L- GSSG aminotransferase: THMPT 2-dehydropantoate a halide anion pyruvate pyruvate pyruvate a tRNA Ala gly a negatively 2-hydroxy-3- his 3-(4- 3-hydroxy- semialdehyde hydroxycarboxylate butyl-thiohydroximate homocysteine an alcohol B753_RS0111125 amino acid sulfanylbutan-1-ol cysteine residues supercoiled DNA oxosuccinate histidine L-kynurenine hydroxyphenyl) trifunctional ammonia- pyruvate kynureninase: transcriptional lyase: hutH (5Z,8Z,11Z,14Z,17Z) an (S)-2- an N 6 -(1-hydroxy-2- S-(4-hydroxy- a monocarboxylic urocanate 4-hydroxyphenylpyruvate kynU regulator/proline a proteinogenic coenzyme A FMNH NAD + 3-methylmuconolactone (R)-glycerate methylglyoxal glutathione -icosapentaenoate 3-methylbutan- triphosphate 2 dioxygenase: hppD dehydrogenase/L- amino acid halocarboxylate oxopropyl)-[protein]-L-lysine acid amide acyl-CoA synthetase: HAD family protein 2-yl)-L-cysteinecystathionine inorganic flavin reductase: muconolactone D-glycerate urocanate 3-hydroxyanthranilate glutamate gamma- gamma- amidase: glyoxalase: homogentisate B753_RS0100040 hydrolase: deglycase HchA: beta-lyase: triphosphatase: B753_RS0101265 delta- dehydrogenase: hydratase: semialdehyde glutamyltransferase: ggt B753_RS0104880 an α-(γ-L-glutamyl) [+ 4 isozymes] B753_RS0109825 B753_RS0102475 B753_RS0101465 [+ 5 isozymes] B753_RS0104000 hutU dehydrogenase: L-cysteinylglycine (5Z,8Z,11Z,14Z,17Z) an (S)-2- B753_RS0106740 isomerase: catC B753_RS0116655 2-methyl-3- + putA -L-amino acid a halide anion (R)-lactate a [protein]-L-lysine pyruvate diphosphate phosphate H NADH FMN 4-methyl-3-oxoadipate- 4-imidazolone- -icosapentaenoyl-CoA hydroxycarboxylate sulfanylbutan-1-ol a monocarboxylate hydroxypyruvate (R)-lactate 5-propanoate 2-amino-3- enol-lactone 4-maleyl- carboxymuconate- glu imidazolonepropionase: 6-semialdehyde acetoacetate a Chi-site containing S-(1- B753_RS0100415 a proteinogenic a dimer of adjacent γ-L-glutamyl-(S)- (R)-3- leukotriene-C4 double stranded RecA hν asp fumarate gly hydroxyhexan- a tRNA sec ser an aliphatic amine (R)-glycerate L-tartrate maleylacetoacetate amino acid thymidines in DNA 2-aminobutanoate hydroxybutanoate N-formimino- DNA with a blunt end deoxyribodipyrimidine 3-yl)-L-cysteine isomerase: maiA gamma- exodeoxyribonuclease L-aspartate oxidase: glutathione cystathionine serine--tRNA ligase: 3-hydroxybutyrate primary-amine D-glycerate tartrate L-glutamate photo-lyase: 4-fumaryl- glycine cleavage L-serine degradation glutamyltransferase: ggt V subunit alpha: recD B753_RS0105675 synthase: beta-lyase: B753_RS0102695 dehydrogenase: oxidase: dehydrogenase: dehydrogenase: α γ a double stranded DNA B753_RS0105470 formimidoylglutamase: acetoacetate leukotriene-D4 an -( -L-glutamyl) succinate B753_RS0108260 B753_RS0106740 an L-seryl- B753_RS0118775 B753_RS0103950 B753_RS0116655 B753_RS0108710 with a RecA protein two adjacent 2-iminosuccinate 3-sulfanylhexan- a [glycine-cleavage -L-amino acid ophthalmate pyruvate [tRNA sec ] 2-hydroxy-3- hutG fumarylacetoacetase: loaded 3' overhang thymidines in DNA acetoacetate an aldehyde hydroxypyruvate complex H protein] 1-ol fahA ser oxosuccinate N 6 -lipoyl-L-lysine glu [+ 2 isozymes] threonine/serine glycine glycine dehydratase: cleavage a single- 7,8-dihydrofolate S-(5- a peptide with L-phenylalanine fumarate cleavage B753_RS0101750 (2S)-methylsuccinyl-CoA acetyl-CoA NADPH H + a ribonucleic acid (S)-2- a phosphatidylcholine reduced riboflavin a primary amine oxaloacetate system stranded RNA monoglutamate hydroxypentan- glu an N-terminal degradation II (anaerobic) system L-serine 3-oxoadipyl-CoA aminobutanoate protein polyribonucleotide dihydrofolate ribonuclease PH: 3-yl)-L-cysteinecystathionine glutamate-- phospholipase D: L-alanine flavin reductase: primary-amine 2-methylcitrate protein ammonia-lyase: thiolase: pcaF aminopeptidase N: H: gcvH nucleotidyltransferase: pnp reductase: B753_RS0110970 beta-lyase: cysteine ligase: B753_RS0115745 B753_RS0109660 oxidase: synthase: phe H: gcvH a 1,2-diacyl- B753_RS0107970 2-aminoprop-B753_RS0101080 a nucleoside a single- [+ 2 isozymes] B753_RS0111785 a nucleoside B753_RS0103950 B753_RS0111140 a [glycine-cleavage 5,6,7,8- a ribonucleic acid B753_RS0106740 B753_RS0100580 choline sn-glycerol [+ 6 isozymes] aspartate/ [+ 3 isozymes]a [glycine-cleavage diphosphate stranded RNA + diphosphate 3-sulfanylpentan- γ-L-glutamyl-(S)- a peptide ala L-methionine degradation complex H protein] N 6 - 2-enoate 4-methyl-3-oxoadipyl-CoA NADP pyruvate (2S,3S)-2- complex H protein] N 6 tetrahydrofolate 3-phosphate riboflavin an aldehyde tyrosine/aromatic I (to L-homocysteine) aminomethyldihydrolipoyl- 1-ol 2-aminobutanoate methylcitrate -dihydrolipoyl-L-lysine aminotransferase: L-lysine B753_RS0111125 L-threonine 3-phenyl-2- met degradation III (to a dimer of adjacent 2'- (2R,3S)-2- trans-∆ 2 , cis-∆ 4 - a (2E,4E)- oxopropanoate S-adenosylmethionine 2-iminopropanoate ν a single a ribonucleoside FMN NAD(P)H + a RNA-DNA hybrid methylglyoxal) glutathione hypoglycin A h [DNA] a type IV prepilin H hydroxypyruvate synthase: deoxycytidines in DNA stranded DNA triphosphate methylisocitrate decadienoyl-CoA dienoyl-CoA glycine deoxyribodipyrimidine exodeoxyribonuclease DNA primase: flavin reductase: ribonuclease HII: methylisocitrate 2,4-dienoyl- hydroxypyruvate 2,4-dienoyl- B753_RS0113690 thr gamma- prepilin peptidase: cleavage photo-lyase: III: xth B753_RS0109660 B753_RS0115110 lyase: CoA reductase: isomerase: CoA reductase: SAM threonine glutamyltransferase: ggt a 2'- B753_RS0108765 B753_RS0112440 system B753_RS0105470 ssDNA/pppN(pN) [+ 5 isozymes] a nucleoside 5'- B753_RS0111135 B753_RS0103850 B753_RS0103535 B753_RS0103850 phenylacetaldehyde dehydrogenase: L-cysteinylglycine hypoglycin B two adjacent 2'- deoxyribonucleoside [DNA] a cleaved type DNA hybrid a peptide + monophosphate protein n -1 NAD(P) FMNH pyruvate succinate L-tryptophan pyruvate B753_RS0108000 deoxycytidines in DNA 5'-monophosphate IV prepilin 2 (2E)-dec-2- tartronate a (2E)-2- H: gcvH L-2-amino-3- NAD-dependent degradation I enoyl-CoA semialdehyde enoyl-CoA oxobutanoate phenylacetaldehyde (via anthranilate) dehydrogenase: SAH a double RNase R degradation 7,8- (2R,3S)-3- a (2E,4Z)- B753_RS0103940 trp a peptidoglycan a uracil in DNA a tRNA precursor canavaninosuccinate H O acetyl-CoA glu ala D-serine degradation stranded DNA substrate RNA dihydromonapterin 2 isopropylmalate dienoyl-CoA lysozyme: ribonuclease uracil-DNA acetyl-CoA phenylacetate adenosylhomocysteinase: DNA exonuclease: dihydroneopterin ribonuclease D: argininosuccinate glutamate-- 3-isopropylmalate 2,4-dienoyl- aminoacetone B753_RS0106330 R: rnr glycosylase: hydrolase: B753_RS0117095 N-Formyl-L- B753_RS0116960 a N-acetylmuramoyl- aldolase: folB B753_RS0118485 lyase: argH cysteine ligase: dehydrogenase: CoA reductase: a single N-acetyl-D- a nucleoside 5'- 6-(hydroxymethyl) B753_RS0113435 B753_RS0117650 D-serine kynurenine primary-amine a 5'-phosphomononucleotide pentapeptide- a diribonucleotide glycolaldehyde a nucleoside 5'- fumarate L-canavanine B753_RS0100580 leuB B753_RS0103850 stranded DNA glucosamine monophosphate -7,8-dihydropterin an apyrimidinic a tRNA γ-L-glutamyl- L-homocysteine D-serine oxidase: diphosphoundecaprenol uracil monophosphate acetate 4-methyl-2- a (3E)-3- site in DNA D-alanine ammonia-lyase: B753_RS0103950 oxopentanoate enoyl-CoA L-glutamate 2-aminoprop-B753_RS0104745 degradation II methylglyoxal 2-enoate L-kynurenine S-(2-hydroxyacyl) UTP (2R,3S)-3- a (2E,4E)- chitin FMNH NADP + an L-cysteine- glutathione glycyl-glycine penicillin G protoheme 2 a phenyl acetate glu glutathione nucleoside triphosphate S-conjugate isopropylmalate dienoyl-CoA L-glutamine heme oxygenase: beta-N- flavin reductase: aspartate/ kynureninase: gamma- penicillin G amidase: hydroxyacylglutathione pyrophosphohydrolase: arylesterase: cystathionine 3-isopropylmalate 2,4-dienoyl- degradation I B753_RS0105045 acetylhexosaminidase: B753_RS0101265 tyrosine/aromatic kynU glutamyltransferase: ggt B753_RS0103935 hydrolase: gloB B753_RS0103490 B753_RS0104685 beta-lyase: dehydratase: CoA reductase: L-aspartate γ-L-glutamyl- a 2-hydroxy (Z,Z)- B753_RS0111605 2-iminopropanoate 2+ [+ 5 isozymes] leuD leuC B753_RS0103850 aminotransferase: L-asparagine L-cysteinylglycine phenylacetate 6-aminopenicillanate glutathione CO Fe α N-acetyl-D- acetate a phenol B753_RS0106740 gln degradation I anthranilate glycylglycine carboxylate biliverdin-IX chitin + UMP B753_RS0111125 degradation I glucosamine H NADPH FMN pyruvate a thiol (2S)-2- a (3E)-3- carbamoyl- asp isopropylmalate enoyl-CoA phosphate synthase: asp asn B753_RS0100945 carB aspartate/ aspartate pyruvate ammonia- [+ 9 isozymes] tyrosine/aromatic asparaginase: lyase: aspA glu aminotransferase: B753_RS0111950 B753_RS0111125 asp fumarate oxaloacetate

an aliphatic an amino an amino a dicarboxylate sulfonate a dicarboxylate a dicarboxylate a dicarboxylate acid acid a sulfonate molybdate a branched- a branched- a branched- 3-(3- glutamate anguibactin D-fructose glycine betaine a long-chain 3,5- 3,5- a C4- a C4- a C4- an aromatic an aromatic an inorganic an inorganic an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a siderophore phosphonate a nucleotide (S)-lactate glutamate D-methionine a lipopolysaccharide a lipopolysaccharide chain chain chain chromate chromate chromate hydroxyphenyl) pro asp malonate malonate an aromatic an aromatic pyrimidine Fe 3+ 1-phosphate L-proline betaine N-acetyl-α-D- fatty acid dimethoxytoluene dimethoxytoluene dicarboxylate dicarboxylate dicarboxylate carboxylate carboxylate anion anion acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA a lipopolysaccharide amino acid amino acid amino acid propanoate amino acid amino acid glucosamine predicted predicted predicted predicted predicted ABC predicted ABC predicted ABC ABC ABC ABC ABC transporter RS0101790 RS0100170 RS0101565 GrpE RS0111100 GltS RS0101785 RS0114350 RS0116435 RS0104320 PgaA RS0110595 LptA efflux transporter of efflux transporter of RS0116300 RS0118620 RS0104950 RS0110875 RS0103705 RS0114675 RS0110550 BrnQ RS0117020 RS0104360 RS0113325 RS0113330 RS0118640 RS0118015 RS0114310 RS0114960 PutP RS0111925 RS0104415 RS0106780 RS0112725 RS0112720 RS0116010 RS0114810 RS0102505 RS0116820 RS0116275 transporter transporter RS0117920 ProY RS0114295 RS0105020 RS0116585 RS0107030 RS0101970 RS0117555 RS0106045 RS0117910 RS0107640 RS0112080 RS0106370 RS0100040 RS0103445 MadL MadM RS0100370 RS0101560 transporter transporter of an a lipopolysaccharide a lipopolysaccharide of an of an of a sulfonate of molybdate aliphatic amino acid amino acid pyrimidine anguibactin glycine betaine sulfonate a long-chain 3,5- 3,5- a C4- a C4- a C4- an aromatic an aromatic a branched- a branched- a branched- an inorganic an inorganic 3-(3- a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a siderophore phosphonate a nucleotide (S)-lactate D-fructose N-acetyl-α-D- chromate chromate chromate an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino malonate malonate glutamate Fe 3+ L-proline betaine D-methionine fatty acid a lipopolysaccharide dimethoxytoluene dimethoxytoluene dicarboxylate dicarboxylate dicarboxylate carboxylate carboxylate chain chain chain anion anion hydroxyphenyl) pro an amino an amino an amino an amino cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate an aromatic an aromatic glucosamine asp acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid amino acid amino acid amino acid propanoate acid acid amino acid a sulfonate molybdate a lipopolysaccharide a lipopolysaccharide acid acid an amino an amino amino acid an aliphatic glutamate sulfonate a dicarboxylate a dicarboxylate a dicarboxylate a dicarboxylate acid acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.