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Acta Okl1-2014.Cdr ACTA POLONIAE PHARMACEUTICA VOL. 72 No. 1 January/February 2015 ISSN 2353-5288 Drug Research EDITOR Aleksander P. Mazurek National Medicines Institute, The Medical University of Warsaw ASSISTANT EDITOR Jacek Bojarski Medical College, Jagiellonian University, KrakÛw EXECUTIVE EDITORIAL BOARD Miros≥awa Furmanowa The Medical University of Warsaw Boøenna Gutkowska The Medical University of Warsaw Roman Kaliszan The Medical University of GdaÒsk Jan Pachecka The Medical University of Warsaw Jan Pawlaczyk K. Marcinkowski University of Medical Sciences, PoznaÒ Janusz Pluta The Medical University of Wroc≥aw Witold Wieniawski Polish Pharmaceutical Society, Warsaw Pavel Komarek Czech Pharmaceutical Society Henry Ostrowski-Meissner Charles Sturt University, Sydney Erhard Rˆder Pharmazeutisches Institut der Universit‰t, Bonn Phil Skolnick DOV Pharmaceutical, Inc. Zolt·n Vincze Semmelweis University of Medicine, Budapest This Journal is published bimonthly by the Polish Pharmaceutical Society (Issued since 1937) The paper version of the Publisher magazine is a prime version. The electronic version can be found in the Internet on page www.actapoloniaepharmaceutica.pl An access to the journal in its electronics version is free of charge Impact factor (2013): 0.693 MNiSW score (2013): 15 points Index Copernicus (2012): 13.18 Charges Annual subscription rate for 2014 is US $ 210 including postage and handling charges. Prices subject to change. Back issues of previously published volumes are available directly from Polish Pharmaceutical Society, 16 D≥uga St., 00-238 Warsaw, Poland. Payment should be made either by bankerís draft (money order) issued to ÑPTFarmî or to our account Millennium S.A. No. 29 1160 2202 0000 0000 2770 0281, Polskie Towarzystwo Farmaceutyczne, ul. D≥uga 16, 00-238 Warszawa, Poland, with the memo Acta Poloniae Pharmaceutica - Drug Research. Warunki prenumeraty Czasopismo Acta Poloniae Pharmaceutica - Drug Research wydaje i kolportaø prowadzi Polskie Towarzystwo Farmaceutyczne, ul. D≥uga 16, 00-238 Warszawa. Cena prenumeraty krajowej za rocznik 2014 wynosi 207,90 z≥ (w tym 5% VAT). PrenumeratÍ naleøy wp≥acaÊ w dowol- nym banku lub UrzÍdzie Pocztowym na rachunek bankowy Wydawcy: Millennium S.A. 29 1160 2202 0000 0000 2770 0281 Polskie Towarzystwo Farmaceutyczne ul. D≥uga 16, 00-238 Warszawa z dopiskiem: prenumerata Acta Poloniae Pharmaceutica - Drug Research. Warunki prenumeraty zagranicznej - patrz tekst angielski. Typeset by RADIUS, Warszawa; Printed by MCP, Marki Acta Poloniae Pharmaceutica ñ Drug Research Volume 72, Number 1 January/February 2015 CONTENTS REVIEW 3. Muhammad Khurram Waqas, Naveed Akhtar, Rehan Dermatological and cosmeceutical benefits of Glycine max Mustafa, Muhammad Jamshaid, Haji Muhammad (soybean) and its active components. Shoaib Khan, Ghulam Murtaza 13. £ukasz Dobrek, Piotr J. Thor The role of prostanoids in the urinary bladder function and a potential use of prostanoid-targeting pharmacological agents in bladder overactivity treatment. ANALYSIS 21. Kinga Lange, Teresa Gierlach-H≥adoÒ Solid state characterization of α-tocopherol in inclusion complexes with cyclodextrins. 31. Urszula Hubicka, Barbara Øuromska-Witek, Joanna Determination of neomycin in the form of neomycin Piotrowska, Jan Krzek derivative with dabsyl chloride by thin layer chromatography and densitometry. 39. Anna Petruczynik, Karol WrÛblewski, Effect of chromatographic conditions on retention behavior Monika Waksmundzka-Hajnos and system efficiency for HPTLC of selected psychotropic drugs on chemically bonded stationary phases. DRUG BIOCHEMISTRY 49. Anna Bilska-Wilkosz, Magdalena Dudek, Joanna Knutelska, Effect of lipoic administration on the urinary excretion of Lidia W≥odek thiocyanate in rats exposed to potassium cyanide. DRUG SYNTHESIS 53. Jerzy Cieplik, Marcin Stolarczyk, Janusz Pluta, Synthesis and antibacterial properties of pyrimidine derivatives. Olaf Gubrynowicz, Iwona Bryndal, Tadeusz Lis, Marcin Mikulewicz 65. Mostafa M. Ghorab, Mansour S. Alsaid, Yassin M. Nissan Novel pyrrolopyrimidines and triazolopyrrolopyrimidines carrying a biologically active sulfonamide moieties as anticancer agents 79. Mostafa M. Ghorab, Mansour S. Alsaid, Cytotoxic activity of some novel sulfonamide derivatives. Abdullah-Al-Dhfyan, Reem K. Arafa 89. Anna Maria Waszkielewicz, Agnieszka Gunia-Krzyøak, Synthesis and evaluation of anticonvulsant activity of Marek Ceg≥a, Henryk Marona N-(2,5-dimethylphenoxy) and N-[(2,3,5- trimethylphenoxy)alkyl]aminoalkanols. 101. Anna Nowicka, Hanna Liszkiewicz, Wanda P. Nawrocka, Synthesis and antiproliferative activity in vitro of new 2- Joanna Wietrzyk, Agnieszka Zubiak, thioxoimidazo[4,5-b] pyridine derivatives. Wojciech Ko≥odziejczyk NATURAL DRUGS 113. Alamgeer, Uzma Mazhar, Muhammad Naveed Mushtaq, Evaluation of anti-inflammatory, analgesic and antipyretic Hafeez Ullah Khan, Safirah Maheen, Muhammad Nasir activities of Thymus serphyllum Linn. in mice. Hayat Malik, Taseer Ahmad, Fouzia Latif, Nazia Tabassum, Abdul Qayyum Khan, Haseeb Ahsan, Wasim Khan, Inrahim Javed, Haider Ali 119. Talent Chipiti, Mohammed Auwal Ibrahim, Neil Anthony In vitro antioxidant activity and GC-MS analysis of the ethanol Koorbanally, Md. Shahidul Islam and aqueous extracts of Cissus cornifolia (Baker) Splanch (Vitaceae) parts. 129. Muhammad Asif, Muhammad Atif, Amin Malik, Diuretic activity of aqueous extract of Nigella sativa in Shah Abdul Majid, Sabbar Dahham, Sawsan Al Ravi, Albino rats. Zahari Che Dan APPHAX 72 (1) 1 ñ 216 (2015) 137. Marina T. Tomovic, Snezana M. Cupara, Marija T. Antioxidant and anti-inflammatory activity of Potentilla reptans L. Popovic-Milenkovic, Biljana T. Ljujic, Marina J. Kostic, Slobodan M. Jankovic 147. Emmanuel E. Nyong, Michael A. Odeniyi, Jones O. Moody In vitro and in vivo antimicrobial evaluation of alkaloidal extracts of Enantia chlorantha stem bars and their formulated ointments. 153. Rachel Dorothy Wilson, Md. Shahidul Islam Effects of white mulberry (Morus alba) leaf tea investigated in a type 2 diabetes model of rats. PHARMACEUTICAL TECHNOLOGY 161. Witold Musia≥, Ji¯Ì Mich·lek The influence of low process temperature on the hydrodynamic radius of polyNIPAM-co-PEG thermosensitive nanoparticles presumed as drug carriers for bioactive proteins. 171 Ehab I. Taha, Saleh A. Al-Suwayeh, Moustafa M. Tayel, Fast ultra-fine self-nanoemulsifying drug delivery system for Mohamed M. Badran improving in vitro gastric dissolution of poor water soluble drug 179. Sofiane Fatmi, Lamine Bournine, Mokrane Iguer-Ouada, Amorphous solid dispersion studies of camptothecinñcyclodextrin Malika Lahiani-Skiba, Fatiha Bouchal, Mohamed Skiba inclusion complexes in PEG 6000. 193. Venkata Srikanth Meka, Shreeni Pillai, Senthil Rajan Preparation and in vitro characterization of non-effervescent Dharmalingham, Ravi Sheshala, Adinarayana Gorajana floating drug delivery system for poorly soluble drug, glipizide. PHARMACOLOGY 205. Monika Rykaczewska-CzerwiÒska, Piotr Oleú, Micha≥ Oleú, Effect of alloferon 1 on central nervous system in rats. Mariola Kuczer, Danuta KonopiÒska, Andrzej Plech SHORT COMMUNICATION 213. Olivera Z. Milovanovic, Jasmina R. Milovanovic, Variation in vitamin D plasma levels according to study load of Aleksandar Djukic, Milovan Matovic, Aleksandra biomedical students. Tomic Lucic, Nenad Glumbic, Ana M. Radovanovic, Slobodan M. Jankovic Acta Poloniae Pharmaceutica ñ Drug Research, Vol. 72 No. 1 pp. 3ñ11, 2015 ISSN 0001-6837 Polish Pharmaceutical Society REVIEW DERMATOLOGICAL AND COSMECEUTICAL BENEFITS OF GLYCINE MAX (SOYBEAN) AND ITS ACTIVE COMPONENTS MUHAMMAD KHURRAM WAQAS1, NAVEED AKHTAR1, REHAN MUSTAFA1, MUHAMMAD JAMSHAID2, HAJI MUHAMMAD SHOAIB KHAN1 and GHULAM MURTAZA3* 1Department of Pharmacy, Faculty of Pharmacy and Alternative Medicines, The Islamia University of Bahawalpur, Bahawalpur, Pakistan 2Department of Pharmacy, University of Central Punjab, Lahore, Pakistan 3Department of Pharmaceutical Sciences, COMSATS Institute of Information Technology, Abbottabad, 22060 Pakistan Abstract: Glycine max, known as the soybean or soya bean, is a species of legume native to East Asia. Soya beans contain many functional components including phenolic acids, flavonoids, isoflavonoids (quercetin, genistein, and daidzein), small proteins (Bowman-Birk inhibitor, soybean trypsin inhibitor) tannins, and proan- thocyanidins. Soybean seeds extract and fresh soymilk fractions have been reported to possess the cosmeceuti- cal and dermatological benefits such as anti-inflammatory, collagen stimulating effect, potent anti-oxidant scav- enging peroxyl radicals, skin lightening effect and protection against UV radiation. Thus, present review attempts to give a short overview on dermatological and cosmeceutical studies of soybean and its bioactive compounds. Keywords: Glycine max, soybean, isoflavonoids, genistein, cosmeceutical, dermatological The soybean (Glycine max) is an annual stituent). Phenolics are plant secondary metabolites legume of the Fabaceae family. It is indigenous to and they are commonly found in herbs and fruits, East Asia and China but now is extensively cultivat- vegetables, grains, tea, coffee beans, propolis, and ed in many temperate regions of the world (1). red wine as a color and flavoring agents and are an Traditionally, soybean has been an excellent source integral part of human diet (5). Naturally occurring of proteins (2). Despite of proteins it is rich in phenolic acids contain two distinguishing constitu- dietary fiber and a variety of micronutrients and tive carbon frameworks: the hydroxycinnamic
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