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ZEISS Medical Technology Company Presentation

Insights 2017/2018 Content ZEISS Medical Technology

1 The ZEISS Group

2 ZEISS Medical Technology at a glance

3 Fascinating Facts

4 Product Portfolio

5 Solution Provider

6 Global MEGS Trends

7 Corporate Social Responsibility

Company Presentation – ZEISS Medical Technology Insights ZEISS Medical Technology

The ZEISS Group

Company Presentation – ZEISS Medical Technology The Power of ZEISS 170 years of company history in Innovations

1st Picture 9,100 Stars of the surface of the Moon can be projected in planetariums taken with lenses from ZEISS using ZEISS optics

Every second 3 Technical Oscars two people decide for helping leading movie-makers to purchase eyeglass capture perfect moments on film lenses from ZEISS

15 million 35 Nobel cataract operations prize-winners are performed annually put their trust in ZEISS around the world using to see more surgical systems from ZEISS

Company Presentation – ZEISS Medical Technology ZEISS The company founders

Carl Zeiss

Their mission . Cutting-edge research . Extreme precision and maximum quality . Responsibility to society

Company Presentation – ZEISS Medical Technology ZEISS Company history

Carl Zeiss First non-German subsidiary Stock corporation opens a workshop in London marks the start ZEISS is transformed into a for precision engineering of global expansion stock corporation – the Carl and optics in Jena Zeiss Foundation remains the sole stockholder

Carl Zeiss Partition Foundation Jena: expropriated Oberkochen: new factory created by Ernst Abbe

1846 1875 1889 since 1890 since 1894 since 1926 after 1945 1991 2004 2016

Reunification Diversification of the two separated companies Innovative products open up new business

200th birthday of Carl Zeiss (1816–1888) Consolidation Ernst Abbe Starts with the founding of Zeiss Ikon AG becomes part owner

Company Presentation – ZEISS Medical Technology Innovation is part of the ZEISS DNA For more than 170 years

Binoculars S-Planar® 10/0.42 DriveSafe with increased objective lithography optics eyeglass lenses distance

Large ophthalmoscope EUV lithography First EUV optics in volume and ZEISS PUNKTAL production eyeglass lenses

First First First X-ray compound surgical OCT microscope microscope

1857 1872 1894 1902 1912 1923 1953 1973 1977 1994 1996 2000 2009 2012 2013 2014 2015 2016

ZEISS ZEISS Freeform LSM 880 technology Airyscan Tessar UMM 500 for individually First produced PiWeb coordinate eyeglass Quality data measuring lenses management for machine industry Abbe's theory Projection ZEISS AIMS ReLEx SMILE, of microscope planetarium system VisuMax resolution First presentation Photomask inspection Femtosecond (Munich) system for chip production laser

Company Presentation – ZEISS Medical Technology Over 30 Nobel laureates worldwide use ZEISS instruments to achieve progress in science

Sir Paul M. Nurse Leland H. Hartwell Eric Betzig Timothy Hunt Stefan W. Hell Physiology/medicine William E. Moerner Craig C. Mello Chemistry Andrew Z. Fire In close collaboration with ZEISS staff Robert Koch Alvar Gullstrand Manfred Eigen Christiane Physiology/medicine Physiology/medicine Physiology/medicine Chemistry Nüsslein- In close collaboration Volhard with ZEISS staff John O'Keefe Physiology/medicine Eric A. Cornell May-Britt In close Physics Moser Edvard collaboration I. Moser with ZEISS staff Physiology/medicine

1905 1906 1911 1925 1952 1953 1967 1991 1995 1999 2001 2002 2006 2008 2010 2011 2012 2013 2014

Sidney Brenner Sir John B. Gurdon Richard Adolf Bert Sakmann Zsigmondy H. Robert Horvitz Shinya Yamanaka Erwin Neher Physiology/medicine Chemistry Physiology or medicine John E. Sulston In close Physiology/medicine collaboration Dan Shechtman with ZEISS staff Chemistry Harald zur Hausen Santiago Ramón y Frits Zernike Günter Blobel Physiology/medicine Cajal Camillo Golgi Physics Physiology/medicine Physiology/medicine In close collaboration Osamu Shimomura with ZEISS staff Ahmed A. Zewail Chemistry Martin Chalfie Roger Tsien Chemistry

In close collaboration with ZEISS staff

Company Presentation – ZEISS Medical Technology Financial highlights 2018/18

5.817 billion euros revenue

772 million euros earnings (EBIT)

≈30,000 employees (worldwide)

As of 30 September 2018

Company Presentation – ZEISS Medical Technology Represented worldwide Sites

Around Headquarters Over 25 research and Oberkochen 60 sales and development centers service sites

Around Around Represented in over 30 production sites 30,000 employees 50 countries

Company Presentation – ZEISS Medical Technology Segments 2017/18

Semiconductor Manufacturing Technology Industrial Quality & Research

1,531* million euros revenue ≈ 3,400 employees 1,549* million euros revenue ≈ 6,800 employees

Medical Technology** Consumer Markets

1,546* billion euros revenue ≈ 4,900 employees 1,106* million euros revenue ≈ 10,500 employees

*As per 30 September 2018 **The values deviate from the published figures of Carl Zeiss Meditec AG as a result of different consolidation models.

Company Presentation – ZEISS Medical Technology Insights ZEISS Medical Technology

ZEISS Medical Technology at a glance

Company Presentation – ZEISS Medical Technology Pioneering Medical Technology ZEISS Medical Technology

Improving quality of life With innovations for ophthalmology and microsurgery, ZEISS Medical Technology is contributing to progress in medicine. Our products and solutions aim to help physicians to improve patient outcomes and their patients’ quality of life.

Company Presentation – ZEISS Medical Technology ZEISS Medical Technology Aspiration & Vision

Our Aspiration Our Vision Enable doctors to efficiently and effectively Become the partner of choice for improve the quality of life of patients and drive the doctors in our segments. the progress of medicine

Company Presentation – ZEISS Medical Technology ZEISS Medical Technology Driving Progress in Medicine through Innovation

As a world-leading medical technology company, we drive progress in medicine, enabling doctors to achieve the best possible outcomes for their patients

Ophthalmic Devices Microsurgery

. Comprehensive solutions to diagnose and treat eye diseases . Complete product range of visualization solutions for minimally invasive surgical treatments (e.g. Neuro, . Systems and consumables for cataract, retinal and refractive ENT, spinal, dental) surgery . Focus on networking of systems and the integrated . Intraoperative diagnostics to enhance effectiveness and safety of management of data, to make workflows in hospitals and medical surgical procedures complete with cutting-edge video technology practices efficient and three-dimensional imaging

Ophthalmic Refractive Surgical Visualization Surgical Oncology Diagnostics Laser Surgery Ophthalmology

Company Presentation – ZEISS Medical Technology Results at a Glance (FY 17/18) Broad Product Portfolio, Balanced Regional Set-up

Growth & Revenue Split by Regions Growth & Revenue Split by SBUs

Americas EMEA APAC Microsurgery Ophthalmic Devices

31.7% 29.5% 38.8% 27 % 73 %

All figures as reported. SBU: Strategic Business Unit

Company Presentation – ZEISS Medical Technology Carl Zeiss Meditec Company Snapshot

. Headquarters in Revenue in € millionen EBIT in € millionen Jena, Germany 861,9 906,4 909,3 1.040,1 1.088,4 1.189,9 1.280,99 122,9 133,8 120,7 130,6 154,3 180,8 197,1 . Around 3,050 employees worldwide . Listed on the TecDAX . 59% of shares held by Carl Zeiss AG 11/12 12/13 13/14 14/15 15/16 16/17 17/18 11/12 12/13 13/14 14/15 15/16 16/17 17/18

Significant sales growth over the last five years

Company Presentation – ZEISS Medical Technology Global Presence More Than 30 Sites Worldwide

Company Presentation – ZEISS Medical Technology Executive Board Carl Zeiss Meditec AG

Dr. Ludwin Monz Justus Felix Wehmer Jan Willem de Cler President & CEO CFO Member of the Management Board Carl Zeiss Meditec AG Carl Zeiss Meditec AG Carl Zeiss Meditec AG

Company Presentation – ZEISS Medical Technology Insights ZEISS Medical Technology

Fascinating Facts

Company Presentation – ZEISS Medical Technology Fascinating Facts ZEISS Medical Technology

Did you know that ...

... an amazing 4 million surgeries have been performed with the OPMI PENTERO 900 or the OPMI Pentero around the globe?

… around 75 percent of all cataract patients come into contact with a product from ZEISS during their treatment?

… over 15 million cataract operations are performed with ZEISS surgical systems all over the world every year?

… today, more than half of all Optical Coherence Tomography Systems (OCT) in ophthalmological practices are ZEISS OCTs?

… in FY 15/16, ZEISS Medical Technology has invested 12.3 percent of its revenue in Research & Development?

Company Presentation – ZEISS Medical Technology Insights ZEISS Medical Technology

Product Portfolio

Company Presentation – ZEISS Medical Technology Broad Product Portfolio We Offer Our Customers an Extensive Portfolio

Customers Segments SBU Products

Ophthalmic Diagnostics Private practitioners Ophthalmic Refractive Surgery Devices Hospitals

Surgical Ophthalmology Clinics

Visualisation & Microsurgery Ambulatory Microsurgery surgery centers Radiotherapy

Company Presentation – ZEISS Medical Technology Insights ZEISS Medical Technology

Solution Provider

Company Presentation – ZEISS Medical Technology More than 100 Years of Leadership in Medical Technology Gold Standard Products Defining the Market

Slit lamp OPMI® HFA™ OCT 1 Perimeter

Pace-setting innovation for more than 100 years

IOLMaster® OPMI® VisuMax® PENTERO System

Company Presentation – ZEISS Medical Technology The Cataract Workflow Integrating Products into Systems

For Better Treatment Efficiencies and Improved Patient Outcomes

VISALIS OPMI® LUMERA® ® CALLISTO eye® IOLMaster phaco® AT LISA tri®

Diagnosis Surgery

Data Management Solution

Company Presentation – ZEISS Medical Technology Bringing Innovation and Patients Together

Identifiying needs & providing solutions

Ongoing service Implementing and support for In the practice maximum uptime & and the OR practice efficiency. . Training . Service . Clinical application specialists . Technical support

Company Presentation – ZEISS Medical Technology Insights ZEISS Medical Technology

Global MEGA Trends

Company Presentation – ZEISS Medical Technology Long-term trends significantly boost our growth Global MEGA Trends

Demographic Technological Globalisation Change Change

Company Presentation – ZEISS Medical Technology Global MEGA Trends Several Key Trends are Influencing Our Markets

Aging of the population and growing Increasing information Budget constraints 1 affluence 2 access and awareness 3

4 Growing patient load, growing expectations 5 Rising access to health care in RDEs Company Presentation – ZEISS Medical Technology Demographic Change The Proportion of Older People is Growing

Demographic Change

Company Presentation – ZEISS Medical Technology Demographic Change Comprehensive Solutions for Typical Age-related Diseases

Dr. Ludwin Monz President & CEO

„The proportion of older people in the overall population is growing in many parts of the world. We offer comprehensive solutions for the diagnosis and treatment of typical age- related diseases.“

Company Presentation – ZEISS Medical Technology Demographic Change Innovations for Age-related Diseases 40 % of the population will develop cataracts

Lens clouded by cataract

Normal vision Vision with cataract CALLISTO eye® assists cataract surgeons with the precision alignment of IOLs

Company Presentation – ZEISS Medical Technology 33 Technological Change The Medical Sector is Rapidly Changing

Technological Change

Company Presentation – ZEISS Medical Technology Technological Leadership Pioneering Refractive Laser Technology

Minimally-invasive refractive laser surgery with ReLEx SMILE

Patients have high expectations of clinical ReLEx® SMILE: Minimally invasive treatment outcomes method sets new standards in refractive surgery

Company Presentation – ZEISS Medical Technology Technological Leadership The Next Generation of Surgical Microscopes

Brilliant visualization in Neurosurgery with ZEISS KINEVO 900

Company Presentation – ZEISS Medical Technology Technological Leadership Innovation in Brain Tumor Treatment

Brain tumor treatment with INTRABEAM 600

Company Presentation – ZEISS Medical Technology Globalisation The World is Converging

Globalisation

Company Presentation – ZEISS Medical Technology Globalisation We Are Well Aware of Our Customers‘ Demands

Dr. Ludwin Monz President & CEO

„Through our global network we are well aware of our customers‘ demands. We use this knowledge to define standards which we then put into practice through international training courses.“

Company Presentation – ZEISS Medical Technology Global Knowledge Sharing Knowledge Through Worldwide Training with the ZEISS ACADEMY

Training workshop In Hong Kong Employee training with customers in Jena

Company Presentation – ZEISS Medical Technology Global Innovation Research and Development in Rapidly Developing Economies

China Mexico South East Asia India Brazil

R&D Centers in rapidly developing economies

Company Presentation – ZEISS Medical Technology Insights ZEISS Medical Technology

Corporate Social Responsibility

Company Presentation – ZEISS Medical Technology Corporate Social Responsibility Eyesight is Not „Normal“ For Everyone

Worldwide …

million 285 million People are visually impaired 39 people are blind

1-2 million people go blind per year

Source: D. Pascolini, S.P. Mariotti, “Global estimates of visual impairment”, Br. J. Ophthalmol. 96, 614 - 618 (2012).

Company Presentation – ZEISS Medical Technology Corporate Social Responsibility Longlasting Cooperation with Christoffel Mission for the Blind (CBM)

ZEISS and the CBM

. The Christoffel Mission for the Blind (CBM) is an international aid organization.

. ZEISS and the CBM have beenpartners for many years: ZEISS supports the CBM in events and with products for its projects in Africa, Asia and South America.

11-year-old Kumar from Nepal has been given the gift of sight thanks to a cataract operation

Company Presentation – ZEISS Medical Technology Corporate Social Responsibility Supporting Doctors to Bring Highest Level of Clinical Care to Their Patients All Over The World

Support for the Fellowship program of the International Council of Ophthalmology (ICO): Every year ZEISS invites ICO fellows – young doctors from developing countries.

Company Presentation – ZEISS Medical Technology Company Presentation – ZEISS Medical Technology