Drug Price Reference 2019

ACKNOWLEDGEMENTS

The 2019 Edition of the Drug Price Reference Index (DPRI) is a product of hard work and dedication of the Department of Health (DOH) Pharmaceutical Division headed by Dr. Anna Melissa S. Guerrero, team efforts of the System Support Unit supervised by Ms. Vanessa J. Saulog – Obera, and led by Mr. Achilles V. Aragona together with the team members namely: Mr. Christian M. Villostas, Mr. John Lester M. Custodio, Ms. Geny C. Belmonte, Mr. Jaldrin Ivan M. Bunag, and Mr. Christian Joel M. Tambong.

The technical contributions of other staff are also acknowledged in particulars: Mr. Aris M. Posadas for continuously enhancing the DPRI website and database and Mr. Adell R. Azuelo for the processing of DPRI booklet printing.

Special thanks also to all NDP Compliance Officers and EDPMS Helpdesks who aided in the implementation of the DPRI and to the DOH-Pharmaceutical Division family. All DOH Retained / Specialty Hospitals and Centers for Health Development (CHDs) for contributing their data to the Department of Health.

Lastly, we thank our Assistant Secretary for Health Regulation Charade B. Mercado- Grande, Undersecretary for Health Regulation Rolando Enrique D. Domingo and Health Secretary Francisco T. Duque III for their unwavering support and commitment in the implementation of the program.

2019 DPRI |Seventh Edition 1 | P a g e OVERVIEW

The high and extremely variable prices of medicines in the Philippines impact on access to effective, efficient and equitable health care. In 2009, a study conducted by Health Action International revealed that there was extreme variability in the procurement prices of essential medicines across the national and local public health facilities in the country. On average, originator brands and generic equivalents were procured almost 16 times and 3 times higher, respectively, compared to prices available on the international market.1

The DOH-Central Bids and Awards Committee (DOH-COBAC) and DOH Hospitals were shown to have more efficient procurement prices compared to provincial and municipal health facilities, thus leading to variability in access to essential medicines across the Philippines.

Republic Act (RA) 9502 or the Universally Accessible Cheaper and Quality Medicines Act of 2008 gave the DOH instruments to monitor and regulate the prices of drugs and medicines to protect consumers and the public procuring entities from excessive mark-ups applied to prices of medicines resulting from information asymmetry and the lack of effective market competition.

To address these issues, the DOH Pharmaceutical Division (formerly NCPAM) established a Drug Price Reference Index (DPRI) for all essential medicines to guide all national and local government health facilities in the efficient sourcing of pharmaceutical products in the public sector.

What is the Drug Price Reference Index (DPRI)?

The DPRI lists the ceiling prices of essential medicines for government bidding and procurement set by the DOH for all National and Local Government Health Facilities and Government Agencies. Winning bid prices of essential medicines within the DPRI ceiling reflect efficient and effective procurement in the government. Their transparency and enforcement ensure consumer access to medicines and protection from excessive price mark-ups on medicines.

______1 Douglas B, Tisocki K (2009) Public Procurement Prices of Medicines in the Philippines. Health Action International. The data coming from reputable suppliers are only considered in the database which means that they should be licensed by the Philippine Food and Drug Administration (FDA) and have certificate of Good Manufacturing Practice issued by the FDA.

2019 DPRI |Seventh Edition 2 | P a g e It aims to improve the efficiency and good governance in the pricing and procurement of medicines in the public sector through establishing a transparent and publicly available reference price for affordable and quality medicines. It also aims to guide the Philippine Health Insurance Corporation (PHIC) in setting reimbursement caps for medicines both for inpatient and outpatient services.

The DPRI only reflects the acquisition costs including landed cost, packaging, drug content, quality assurance, manufacturing overheads and Food and Drug Administration (FDA) fees. The DPRI excludes other costs such as pharmacy services, preparation and storage fees, and other reasonable pharmacy mark- ups, which are now being evaluated by the DOH.

Who should use the DPRI?

All government entities should be guided by the DPRI when procuring medicines. It shall be applied to all forms of procurement such as public bidding, direct contracting, shopping, negotiated procurement, emergency procurement and consignment to ensure that the government achieves the best value for money in sourcing essential medicines.

What are the sources of Price Data?

The DPRI is computed based on the prevailing tender prices of the previous year (2018) reflected in the actual Purchase Orders (POs) submitted by the DOH Retained Hospitals, Centers for Health Development (CHDs), Central Office Bids and Awards Committee (COBAC) and Philippine Pharma Procurement Inc. (PPPI) to the DOH.

How the Drug Price Reference Index (DPRI) determined?

The reference price is set at the Median or the 50th percentile across the range of prevailing tender prices of essential medicines for each preparation and strength. However, for drugs and medicines with two entries, for patented drugs and medicines and with limited competition the reference price was set to lowest. Health facilities may add an allowable margin up to 10% to account for the inflation.

2019 DPRI |Seventh Edition 3 | P a g e How often is the DPRI updated?

The DPRI is updated annually. All DOH hospitals and CHDs submit a copy of their latest Purchase Orders to the DOH Pharmaceutical Division for annual collection and analysis of price data. The updated DPRI is based on the procurement price data of medicines from the previous year.

How to set the ABC of medicines not included in this edition?

In case where the latest DPRI published has no reference price available for certain essential medicines, government health facilities and agencies may do any of the following options in compliance with the Implementing Rules and Regulations (IRR) of Republic Act (RA) 9184 or the Government Procurement Act: o The facility may utilize the previous year’s awarded price as an approved budget for the contract (ABC). o The procuring entity may conduct a market survey and use the cheapest price in the market.

Occurrence of Bid Failure

In case of failed biddings, provision of RA 9184 and its IRR shall be applied. All procuring entities are advised to submit the list of medicines that resulted in bid failure to the DOH-PD. The report should comply the template provided by DOH-PD which can be downloaded at their website at www.dpri.doh.gov.ph.

2019 DPRI |Seventh Edition 4 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) A 1. Acetazolamide 250 mg Tablet 20.00 - 20.00 20.00 2. Acetylcysteine 100 mg Sachet 7.00 - 11.54 9.00 3. Acetylcysteine 100 mg/mL, 3 mL Ampule 84.00 - 118.55 84.00 4. Acetylcysteine 200 mg Sachet 7.50 - 16.67 10.00 5. Acetylcysteine 200 mg/mL, 25 mL Bottle 1,261.26 - 1,261.26 1,545.00 6. Acetylcysteine 600 mg Effervescent Tablet 12.00 - 37.25 22.00 7. Aciclovir 200 mg Tablet 3.04 - 8.88 4.84 8. Aciclovir 25 mg/mL, 10 mL Vial 512.23 - 1,183.22 977.43 9. Aciclovir 400 mg Tablet 4.29 - 30.00 13.28 10. Aciclovir 800 mg Tablet 16.25 - 56.07 40.00 11. Adenosine 3 mg/mL, 2 mL Vial 167.33 - 2,200.00 221.32 12. Albumin, Human 20%, 50 mL Bottle 1,760.00 - 1,920.11 2,750.00 13. Albumin, Human 25%, 50 mL Bottle 1,997.12 - 2,275.00 3,250.00 14. Alcohol, Ethyl 70% solution, 500 mL Bottle 48.95 - 51.00 50.00 15. Alendronate Sodium 70 mg Tablet 34.00 - 195.00 129.00 16. All-in-One Admixtures ("3-in-1" or "dual energy" 2,000.00 - 2,000.00 solutions) "3 in 1" 1000 Kcal Bottle 3,280.00 17. All-in-One Admixtures ("3-in-1" or "dual energy" 3,100.00 - 3,900.00 solutions) "3 in 1" 1300 Kcal Bottle 5,200.00 18. All-in-One Admixtures ("3-in-1" or "dual energy" 1,600.00 - 1,988.00 solutions) "3 in 1" 1400 Kcal Bottle 3,640.00 19. All-in-One Admixtures ("3-in-1" or "dual energy" 3,500.00 - 3,500.00 solutions) "3 in 1" 1500 Kcal Bottle 4,800.00 20. All-in-One Admixtures ("3-in-1" or "dual energy" 1,750.00 - 3,643.17 solutions) "3 in 1" 1900 Kcal Bottle 5,100.00 21. Allopurinol 100 mg Tablet 0.50 - 6.92 2.80 22. Allopurinol 300 mg Tablet 0.85 - 13.00 2.09 23. Alprazolam 250 mcg Tablet 4.10 - 20.00 4.10 24. Alprazolam 500 mcg Tablet 8.00 - 30.00 18.00

Health facilities may have a price variation up to 10% above the DPRI to account for inflation

2019 DPRI |Seventh Edition 5 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 25. Aluminum Hydroxide + Magnesium Hydroxide 25.00 - 40.77 35.00 225 mg + 200 mg/5 mL, 120 mL Suspension 26. Aluminum Hydroxide + Magnesium Hydroxide 13.75 - 56.00 33.00 225 mg + 200 mg/5 mL, 60 mL Suspension 27. Amikacin (as Sulfate) 100 mg/mL, 2 mL Vial 22.89 - 24.33 22.89 28. Amikacin (as Sulfate) 125 mg/mL, 2 mL Ampule 18.22 - 44.23 22.96 29. Amikacin (as Sulfate) 125 mg/mL, 2 mL Vial 16.12 - 56.00 22.78 30. Amikacin (as Sulfate) 250 mg/mL, 2 mL Ampule 21.33 - 298.00 27.30 31. Amikacin (as Sulfate) 250 mg/mL, 2 mL Vial 18.12 - 61.22 18.12 32. Amikacin (as Sulfate) 50 mg/ml, 2 ml Vial 18.34 - 39.77 18.34 33. Amikacin (as Sulfate) 500 mg powder Vial 7.98 - 67.75 16.34 34. Amino Acid Solutions for Hepatic Failure 8%, 301.00 - 973.00 301.00 500 mL Bottle 35. Amino Acid Solutions for Infants 6%, 100 mL 370.00 - 492.80 370.00 Bottle 36. Amino Acid Solutions for Renal Conditions 7%, 392.00 - 784.00 392.00 500 mL Bottle 37. Amino Acids, Crystalline Standard 10%, 500 mL 800.00 - 1,150.00 800.00 Plastic Bottle 38. Amino Acids, Crystalline Standard 5%, 500 mL 425.00 - 500.00 425.00 Plastic Bottle 39. Amino Acids, Crystalline Standard 6%, 100 mL 360.00 - 400.00 360.00 Glass Bottle 40. Amino Acids, Crystalline Standard 6%, 100 mL 359.00 - 360.00 359.00 Plastic Bottle 41. Amino Acids, Crystalline Standard 7%, 500 mL 392.00 - 769.00 392.00 Plastic Bottle 42. Amino Acids, Crystalline Standard 9.12%, 20 mL 163.20 - 187.75 163.20 Ampule 43. Aminophylline 25 mg/mL, 10 mL Ampule 8.22 - 44.44 23.09 44. Amiodarone 200 mg Tablet 5.30 - 35.50 21.65 45. Amiodarone 50 mg/mL, 3 mL Ampule 133.31 - 550.00 231.86 46. Amlodipine 10 mg Tablet 0.35 - 8.20 0.67 47. Amlodipine 5 mg Tablet 0.23 - 5.00 0.47 48. Amoxicillin 100 mg/mL, 15 mL Drops 14.00 - 42.00 19.37

Health facilities may have a price variation up to 10% above the DPRI to account for inflation 2019 DPRI |Seventh Edition 6 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 49. Amoxicillin 250 mg Capsule 0.85 - 2.31 1.11 50. Amoxicillin 250 mg/5 mL, 60 mL Suspension 15.10 - 60.00 21.15 51. Amoxicillin 500 mg Capsule 0.97 - 4.50 1.28 52. Amphotericin B (Lipid Complex) 50 mg Vial 1,435.00 - 10,424.88 10,435.00 53. Amphotericin B (Non-Lipid Complex) 50 mg Vial 1,390.00 - 2,450.00 3,325.00 54. Ampicillin + Sulbactam 1.5 g Vial 45.49 - 415.00 63.22 55. Ampicillin + Sulbactam 500mg + 250 mg Vial 16.77 - 400.69 23.45 56. Ampicillin 1 g Vial 7.99 - 34.00 11.29 57. Ampicillin 250 mg Vial 6.98 - 33.00 8.89 58. Ampicillin 500 mg Vial 6.12 - 62.94 8.21 59. Aripiprazole 10 mg Tablet 49.89 - 143.50 60.00 60. Ascorbic Acid (Vitamin C) 100 mg/5 mL, 120 mL 15.00 - 85.00 32.86 Syrup 61. Ascorbic Acid (Vitamin C) 100 mg/5 mL, 60 mL 11.31 - 39.50 20.50 Syrup 62. Ascorbic Acid (Vitamin C) 100 mg/ml, 15 mL 11.31 - 48.88 17.64 Oral Drops 63. Ascorbic Acid (Vitamin C) 250 mg/mL, 2 mL 14.50 - 42.00 29.38 Ampule 64. Ascorbic Acid (Vitamin C) 500 mg Tablet 0.45 - 3.20 0.86 65. Asparaginase 10,000 IU Vial 1,495.00 - 1,698.00 2,008.35 66. Aspirin 80 mg Tablet 0.44 - 2.10 0.78 67. Atenolol 100 mg Tablet 2.59 - 3.57 2.59 68. Atenolol 50 mg Tablet 1.54 - 7.00 2.15 69. Atorvastatin 10 mg Tablet 2.10 - 11.54 4.46 70. Atorvastatin 20 mg Tablet 2.26 - 18.20 6.13 71. Atorvastatin 40 mg Tablet 4.30 - 25.00 11.51 72. Atorvastatin 80 mg Tablet 5.99 - 28.50 22.00 73. Atracurium 10 mg/mL, 2.5 mL Ampule 59.88 - 230.00 86.33 74. Atropine 1 mg/mL, 1 mL Ampule 5.23 - 36.98 13.67

Health facilities may have a price variation up to 10% above the DPRI to account for inflation

2019 DPRI |Seventh Edition 7 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 75. Azathioprine 50 mg tablet - 38.42 76. Azithromycin 200 mg/5 mL, 15 mL Suspension 110.67 - 395.00 270.00 77. Azithromycin 500 mg Tablet 8.25 - 130.00 9.24 78. Azithromycin 500 mg Vial 258.00 - 700.00 519.29 79. Aztreonam 1 g Powder 987.33 - 1,488.00 1,244.00 B 80. Baclofen 10 mg Tablet 10.00 - 26.15 13.80 81. Beractant 25 mg/mL, 4 mL Vial 10,073.00 - 10,073.00 11,070.25 82. Beractant 25 mg/mL, 8 mL Vial - 15,776.53 83. Basiliximab 20 mg vial - 60,445.83 84. Betahistine 16 mg Tablet 7.80 - 62.00 12.00 85. Betahistine 24 mg Tablet 26.00 - 54.12 40.00 86. Betahistine 8 mg Tablet 4.90 - 16.00 10.99 87. Betamethasone Cream 0.1%, 5 g Tube 39.65 - 221.67 50.82 88. Betamethasone Ointment 0.1%, 5 g Tube 51.64 - 51.64 51.64 89. Biperiden Hydrochloride 2 mg Tablet 3.91 - 12.80 4.78 90. Bisacodyl 10 mg Suppository 10.22 - 44.75 19.63 91. Bisacodyl 5 mg Suppository 0.77 - 49.30 16.50 92. Bisacodyl 5 mg Tablet 0.60 - 12.00 1.85 93. Bisoprolol 5 mg Tablet 18.00 - 19.97 18.00 94. Bleomycin (as Sulfate) 15 mg Vial 1,900.00 - 1,900.00 2,400.00 95. Budesonide + Formoterol 160 mcg + 4.5 mcg x 681.35 - 1,002.55 681.35 60 doses Dry Powder Inhaler 96. Budesonide 250 mcg/mL, 2 mL Respiratory 18.76 - 65.00 36.60 Solution (Nebule) 97. Bumetanide 1 mg Tablet 21.08 - 23.52 21.08 98. Bupivacaine 0.5% (isobaric), 5 mL (spinal) (as 108.00 - 288.88 142.00 hydrochloride) Ampule 99. Bupivacaine 0.5%, 10 mL Ampule 67.88 - 281.00 103.33

2019 DPRI |Seventh Edition 8 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 100. Bupivacaine 0.5%, 10 mL Vial 98.00 - 324.88 98.00 101. Bupivacaine 0.5%, 4 mL (spinal) with 8% 47.22 - 587.44 120.00 Dextrose (as hydrochloride) Ampule 102. Bupivacaine 0.5%, 5 mL Ampule 125.00 - 129.55 125.00 103. Butamirate Citrate 50mg MR Tablet 8.70 - 16.00 13.00 104. Butamirate Citrate 7.5 mg/5 mL, 120 mL Syrup 170.00 - 236.99 170.00 105. Butorphanol (as Tartrate) 2 mg/mL, 1 mL 392.22 - 567.00 472.61 Ampule 106. Butorphanol (as Tartrate) 2 mg/mL, 1 mL Vial 509.00 - 560.00 509.00 C 107. Calcitriol 0.25 mcg Capsule 24.03 - 25.10 24.03 108. Calcium Carbonate + Cholecalciferol (Vit. D3) 4.00 - 6.20 5.05 600 mg elementa Ca + 400 IU Vit. D3 Tablet 109. Calcium Carbonate 500 mg Chewable Tablet 3.00 - 5.00 4.09 110. Calcium Carbonate 500 mg Tablet 0.85 - 5.00 2.99 111. Calcium Folinate (Leucovorin Calcium) 10 158.80 - 222.00 158.80 mg/mL, 5 mL Ampule 112. Calcium Folinate (Leucovorin Calcium) 10 146.75 - 510.00 218.85 mg/mL, 5 mL Vial 113. Calcium Folinate (Leucovorin Calcium) 50 mg 135.00 - 470.00 135.00 powder Vial 114. Calcium Gluconate 10%, 10 mL Ampule 13.88 - 76.34 18.48 115. Calcium Gluconate 10%, 10 mL Vial 17.88 - 18.48 18.43 116. Calcium Gluconate 10%, 20 mL Bottle 26.33 - 50.00 38.17 117. Capecitabine 500 mg Tablet 44.00 - 80.00 51.00 118. Captopril 25 mg Tablet 0.40 - 3.75 0.91 119. Captopril 50 mg Tablet 1.40 - 3.68 1.40 120. Carbamazepine 200 mg MR Tablet 1.73 - 2.11 1.73 121. Carbamazepine 200 mg Tablet 1.27 - 4.95 2.05 122. Carbetocin 100 mcg/mL, 1 mL Ampule 1,200.00 - 1,200.00 1,200.00 123. Carbetocin 100 mcg/mL, 1 mL Vial - 933.00●

2019 DPRI |Seventh Edition 9 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 124. Carboplatin 10 mg/mL, 15 mL Vial 750.00 - 998.00 898.00 125. Carboplatin 10 mg/mL, 45 mL Vial 1,145.00 - 2,046.00 2,772.00 126. Carboplatin 150 mg powder Vial 594.00 - 975.75 825.00 127. Carboplatin 450 mg powder Vial 1,098.00 - 1,559.57 2,350.00 128. Carboprost 125 mcg/0.5 mL Solution 124.00 - 288.00 179.50 129. Carboprost 250 mcg/mL Solution 219.00 - 950.00 305.00 130. Carvedilol 25 mg Tablet 3.50 - 9.50 4.88 131. Carvedilol 6.25 mg Tablet 0.89 - 9.00 1.38 132. Castor Oil 60 mL Bottle 38.10 - 69.56 38.10 133. Cefalexin 100 mg/mL, 10 mL Drops 13.44 - 111.50 20.00 134. Cefalexin 250 mg/5 mL, 60 mL Bottle 20.60 - 60.00 26.50 135. Cefalexin 500 mg Capsule 1.95 - 8.17 2.58 136. Cefazolin 1 g Vial 14.98 - 119.00 16.60 137. Cefazolin 500 mg Vial 28.77 - 39.88 28.77 138. Cefepime 1 g Vial 61.99 - 204.33 91.72 139. Cefepime 2 g Vial 114.22 - 418.00 204.24 140. Cefepime 500 mg Vial 104.21 - 680.00 148.73 141. Cefixime 100 mg/5 mL, 60 mL Suspension 75.00 - 440.00 175.00 142. Cefixime 20 mg/mL, 10 mL Suspension 85.00 - 200.85 150.00 143. Cefixime 200 mg Capsule 2.77 - 23.77 8.78 144. Cefotaxime (as Sodium) 500 mg + 2 mL diluent 33.45 - 63.44 47.33 Vial 145. Cefotaxime 500 mg + 2 mL diluent Vial 46.12 - 63.44 46.12 146. Cefotaxime 500 mg Vial 46.12 - 47.34 46.12 147. Cefoxitin 1 g Vial 27.32 - 814.87 99.44 148. Ceftazidime 1 g Vial 30.89 - 290.00 37.43 149. Ceftazidime 500 mg Vial 54.39 - 651.94 306.72 150. Ceftriaxone 1 g + 10 mL diluent Vial 14.89 - 550.00 19.94 151. Cefuroxime 1.5 g Vial 105.00 - 179.00 120.00 152. Cefuroxime 125 mg/5 mL, 70 mL Suspension 115.88 - 225.00 172.50

Health facilities may have a price variation up to 10% above the DPRI to account for inflation 2019 DPRI |Seventh Edition 10 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 153. Cefuroxime 250 mg Vial 17.89 - 190.00 103.95 154. Cefuroxime 250 mg/5 mL, 120 mL Granule for 212.00 - 270.00 245.00 suspension 155. Cefuroxime 250 mg/5 mL, 50 mL Bottle 136.50 - 212.00 178.04 156. Cefuroxime 500 mg Tablet 2.49 - 45.00 9.88 157. Cefuroxime 750 mg Vial 13.89 - 290.00 16.87 158. Celecoxib 100 mg Capsule 4.20 - 7.56 4.20 159. Celecoxib 200 mg Capsule 1.95 - 19.00 3.96 160. Celecoxib 400 mg Capsule 10.00 - 29.00 15.00 161. Cetirizine (as Dihydrochloride) 2.5 mg/mL, 10mL 22.50 - 78.10 45.00 Syrup 162. Cetirizine (as Dihydrochloride) 5 mg/5 mL, 30 29.76 - 85.00 56.85 mL Syrup 163. Cetirizine 1 mg/mL, 30 mL Bottle 46.00 - 108.81 82.36 164. Cetirizine 1 mg/mL, 60 mL Bottle 26.19 - 120.00 62.00 165. Cetirizine 10 mg Tablet 0.03 - 23.55 0.43 166. Cetirizine 10 mg/mL, 10 mL Oral Drops 40.00 - 126.74 75.32 167. Cetirizine 5 mg/5 mL, 30 mL Syrup 70.00 - 75.50 70.00 168. Chloramphenicol 1 g Vial 22.89 - 49.78 22.89 169. Chloramphenicol 125 mg/5 mL, 60 mL 22.00 - 49.25 32.23 Suspension 170. Chloramphenicol 500 mg Capsule 2.30 - 4.50 2.95 171. Chlorhexidine Gluconate 0.12%, 120 mL Bottle 105.00 - 120.00 105.00 172. Chlorphenamine (Chlorpheniramine) 10 mg/mL,1 6.12 - 20.80 15.00 mL Ampule 173. Chlorphenamine (Chlorpheniramine) 4 mg Tablet 0.25 - 0.97 0.44 174. Chlorpromazine 100 mg Tablet 1.15 - 6.54 1.49 175. Chlorpromazine 200 mg Tablet 1.64 - 76.88 2.13 176. Ciclosporin 100 mg/mL solution, 50 mL - 7,431.02 177. Cilostazol 100 mg Tablet 3.75 - 25.00 12.98 178. Cilostazol 50 mg Tablet 2.77 - 13.26 7.88

2019 DPRI |Seventh Edition 11 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 179. Cinnarizine 25 mg Tablet 0.38 - 2.30 1.40 180. Ciprofloxacin 2 mg/mL,100 mL Vial 16.79 - 745.29 25.43 181. Ciprofloxacin 500 mg Tablet 1.04 - 31.00 1.32 182. Cisplatin 1 mg/mL, 10 mL Vial 128.00 - 257.00 166.32 183. Cisplatin 1 mg/mL, 50 mL Vial 293.44 - 570.00 378.00 184. Clarithromycin 125 mg/5 mL, 50 mL Suspension 96.00 - 294.00 160.32 185. Clarithromycin 250 mg Tablet 9.0 - 10.36 9.00 186. Clarithromycin 500 mg Tablet 7.20 - 43.08 10.64 187. Clindamycin 150 mg Capsule 1.68 - 12.02 3.90 188. Clindamycin 150 mg/mL, 2 mL Ampule 65.00 - 1,172.00 100.70 189. Clindamycin 150 mg/mL, 4 mL Ampule 51.22 - 210.00 73.44 190. Clindamycin 300 mg Capsule 2.10 - 13.00 6.13 191. Clindamycin 75 mg/5 mL, 60 mL Suspension 185.00 - 214.00 185.00 192. Clobetasol Cream 0.05%, 5 g Tube 50.21 - 100.00 85.00 193. Clonazepam 2 mg Tablet 3.18 - 11.50 8.15 194. Clonidine 150 mcg Tablet 7.00 - 23.00 12.00 195. Clonidine 150 mcg/mL, 1 mL Ampule 8.34 - 151.39 98.00 196. Clonidine 75 mcg Tablet 1.19 - 20.00 5.99 197. Clopidogrel 75 mg Tablet 1.09 - 10.30 1.29 198. Cloxacillin (as Sodium) 250 mg/5 mL, 60 mL 23.75 - 64.00 36.53 Bottle 199. Cloxacillin (as Sodium) 500 mg Capsule 1.86 - 6.15 3.00 200. Clozapine 100 mg Tablet 5.45 - 32.88 9.75 201. Clozapine 25 mg Tablet 8.00 - 18.00 8.00 202. Co -Amoxiclav (Amoxicillin + Potassium 9.10 - 25.00 16.75 Clavulanate) 1 g Tablet 203. Co -Amoxiclav (Amoxicillin + Potassium 102.40 - 209.13 156.40 Clavulanate) 200 mg + 28.5 mg/5 mL, 70 mL Suspension 204. Co -Amoxiclav (Amoxicillin + Potassium 98.00 - 321.92 209.25 Clavulanate) 400 mg + 57 mg/5 mL, 70 mL Suspension

Health facilities may have a price variation up to 10% above the DPRI to account for inflation

2019 DPRI |Seventh Edition 12 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 205. Co -Amoxiclav (Amoxicillin + Potassium 5.10 - 30.00 9.90 Clavulanate) 500 mg + 125 mg Tablet 206. Co -Amoxiclav (Amoxicillin + Potassium 6.99 - 11.80 10.25 Clavulanate) 625 mg Tablet 207. Co -Amoxiclav (Amoxicillin + Potassium 11.00 - 34.50 14.73 Clavulanate) 875 mg + 125 mg Tablet 208. Colchicine 500 mcg Tablet 1.47 - 3.50 2.28 209. Colistin 2,000,000 IU Lyophilized Powder 1,730.00 - 1,730.00 2,500.00 210. Cotrimoxazole (Sulfamethoxazole + 0.63 - 1.90 1.03 Trimethoprim) 400 mg + 80 mg Tablet 211. Cotrimoxazole (Sulfamethoxazole + 18.02 - 45.00 30.50 Trimethoprim) 400 mg + 80 mg/5 mL, 60 mL Suspension 212. Cotrimoxazole (Sulfamethoxazole + 1.10 - 4.56 2.00 Trimethoprim) 800 mg+160 mg Tablet 213. Cyclophosphamide 1 g powder Vial 150.00 - 358.98 247.50 214. Cyclophosphamide 500 mg powder Vial 10.00 - 340.00 156.00 215. Cytarabine 100 mg/mL, 1 mL Vial 100.25 - 135.00 117.88 216. Cytarabine 100 mg/mL, 5 mL Vial 370.00 - 398.75 381.50 217. Cytarabine 20 mg/mL, 5 mL Ampule 112.00 - 157.00 121.00 D 218. Dacarbazine 200 mg Vial 518.00 - 700.00 653.88 219. Dactinomycin (Actinomycin D) 500mcg powder 400.00 - 500.00 400.00 Vial 220. Deferasirox 250 mg Dispersible Tablet 674.52 - 674.52 674.52 221. Deferoxamine 500 mg Vial - 183.32 222. Dexamethasone 4 mg Tablet 1.50 - 27.61 21.82 223. Dexamethasone 4 mg/mL, 2 mL Ampule 7.30 - 50.50 12.33 224. Dexamethasone 4 mg/mL, 2 mL Vial 11.22 - 60.00 12.00 225. Dexamethasone 4 mg/mL,1 mL Ampule 10.88 - 21.88 10.88 226. Dexamethasone 5 mg/mL,1 mL Ampule 16.33 - 110.33 39.88

2019 DPRI |Seventh Edition 13 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 227. Diazepam 5 mg Tablet 6.89 - 8.60 8.12 228. Diazepam 5 mg/mL, 2 mL Ampule 53.44 - 178.88 79.36 229. Diclofenac 25 mg/mL, 3 mL Ampule 9.78 - 49.00 16.45 230. Diclofenac 50 mg Tablet 0.28 - 1.25 0.75 231. Dicycloverine (Dicyclomine) 10 mg Tablet 0.27 - 4.00 0.77 232. Dicycloverine (Dicyclomine) 10 mg/5 mL, 60 mL 10.63 - 36.00 19.50 Syrup 233. Digoxin 250 mcg Tablet 3.28 - 5.20 4.25 234. Digoxin 250 mcg/mL, 2 mL Ampule 93.22 - 194.57 118.34 235. Digoxin 50mcg/mL, 60mL Elixir 606.32 - 837.00 716.22 236. Diltiazem 60 mg Tablet 3.27 - 50.73 19.00 237. Dimeglumine Gadopentetate 469 mg/mL, 10 mL 1,508.00 - 1,508.00 Vial 2,600.00 238. Diphenhydramine (as Hydrochloride) 12.5 mg/ 5 10.71 - 55.00 19.00 mL, 60 mL Syrup 239. Diphenhydramine (as Hydrochloride) 50 mg 0.61 - 5.00 1.21 Capsule 240. Diphenhydramine (as Hydrochloride) 50 mg/mL, 1.63 - 86.00 22.33 1 mL Ampule 241. Divalproex Sodium 250 mg Extended Release 12.79 - 30.00 13.60 Tablet 242. Divalproex Sodium 250 mg Tablet 12.79 - 30.80 23.87 243. Divalproex Sodium 500 mg Film coated tablet 10.00 - 28.00 13.90 244. Dobutamine 2 mg/mL, 250 mL D5W Pre-mixed 58.88 - 976.13 812.71 245. Dobutamine 50 mg/mL, 5 mL Ampule 89.00 - 420.00 200.00 246. Doc etaxel 20 mg/0.5 mL, 0.5 mL Vial 820.00 - 1,500.00 1,110.25 247. Docetaxel 40 mg/mL, 2 mL Vial 977.00 - 4,000.00 3,222.50 248. Domperidone 1 mg/mL, 60 mL Suspension 42.00 - 170.00 90.00 249. Domperidone 10 mg Tablet 0.78 - 7.35 2.11 250. Donepezil Hydrochloride 5 mg Tablet 10.00 - 11.70 10.00 251. Dopamine 1.6 mg/mL, 250 mL D5W Pre-mixed 58.00 - 374.00 350.33 252. Dopamine 40 mg/mL, 5 mL Ampule 24.88 - 110.00 41.89 253. Dopamine 40 mg/mL, 5 mL Vial 31.11 - 59.89 41.77

Health facilities may have a price variation up to 10% above the DPRI to account for inflation

2019 DPRI |Seventh Edition 14 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 254. Dopamine 800 mcg/mL, 250 mL D5W Pre- 270.00 - 389.33 325.00 mixed 255. Doxorubicin 10 mg powder Vial 152.75 - 238.00 176.25 256. Doxorubicin 2 mg/mL, 25 mL Vial 400.00 - 689.00 485.00 257. Doxorubicin 2 mg/mL, 5 mL Vial 146.00 - 363.00 183.75 258. Doxorubicin 50 mg powder Vial 420.00 - 921.23 520.00 259. Doxycycline (as Hyclate) 100 mg Capsule 0.77 - 16.25 1.23 260. Dydrogesterone 10 mg Tablet 43.26 - 56.24 51.83 E 261. Enalapril 20 mg Tablet 9.50 - 11.75 9.66 262. Enalapril 5 mg Tablet 2.40 - 8.80 4.82 263. Enoxaparin 100 mg/mL, 0.2 mL Pre-filled syringe 417.20 - 479.00 417.20 264. Enoxaparin 100 mg/mL, 0.4 mL Pre-filled syringe 179.44 - 564.75 197.23 265. Enoxaparin 100 mg/mL, 0.6 mL Pre-filled syringe 258.00 - 655.00 286.79 266. Ent eral Nutrition - Adult Polymeric 400 g Can 217.00 - 510.00 275.00 267. Enteral Nutrition - Disease-Specific (Diabetes) 300.00 - 558.00 300.00 400 g Can 268. Enteral Nutrition - Fiber-Containing 400 g Can 200.00 - 510.00 200.00 269. Eperisone Hydrochloride 50 mg Tablet 10.00 - 45.00 14.00 270. Ephedrine 50 mg/mL, 1 mL Ampule 75.00 - 148.00 91.50 271. Epinephrine 1 mg/mL, 1 mL Ampule 7.67 - 66.00 24.42 272. Epirubicin 10 mg Vial 655.00 - 810.00 692.50 273. Epirubicin 50 mg Vial 1,360.00 - 2,667.00 2,988.00 274. Epoetin Alfa (recombinant human erythropoietin) 1,048.00 - 1,500.00 10,000 IU/mL Pre-filled syringe 1,549.00 275. Epoetin Alfa (recombinant human erythropoietin) 250.00 - 400.00 250.00 2000 IU/0.5 mL Pre-filled syringe 276. Epoetin Alfa (recombinant human erythropoietin) 214.11 - 784.00 410.30 4000 IU/0.4 mL Pre-filled syringe 277. Epoetin Alfa (recombinant human erythropoietin) 214.11 - 398.33 294.23 4000 IU/mL, 1 mL Vial

Health facilities may have a price variation up to 10% above the DPRI to account for inflation

2019 DPRI |Seventh Edition 15 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 278. Epoetin Beta (recombinant erythropoietin) 10000 3,201.00 - 3,201.00 IU/0.6 mL Pre-filled syringe 3,660.00 279. Epoetin Beta (recombinant erythropoietin) 2000 407.67 - 475.31 407.67 IU/ 0.3 mL Pre-filled syringe 280. Epoetin Beta (recombinant erythropoietin) 978.00 - 1,272.18 978.00 5000IU/0.3ml Pre-filled syringe 281. Ertapenem (as Sodium) 1 g Vial 2,262.00 - 2,262.00 3,016.02 282. Erythromycin 200 mg/5 mL, 60 mL Suspension 37.04 - 57.65 52.25 283. Erythromycin 500 mg Tablet 3.56 - 35.00 5.93 284. Erythromycin Eye Ointment 0.5%, 3.5 g Tube 89.00 - 173.44 124.24 285. Erythromycin Eye Ointment 0.5%, 5 g Tube 94.33 - 230.00 143.00 286. Escitalopram (as Oxalate) 10 mg Tablet 3.15 - 34.00 3.80 287. Esmolol 10 mg/mL, 10 mL Vial 512.23 - 793.44 689.44 288. Esmolol 100 mg/mL, 10 mL Vial 499.00 - 748.88 499.00 289. Ethambutol Hydrochloride 400 mg Tablet 1.63 - 10.33 3.41 290. Etoposide 20 mg/mL, 5 mL Ampule 320.00 - 399.50 345.00 291. Etoposide 20 mg/mL, 5 mL Vial 219.00 - 435.00 400.00 F 292. Famotidiner 20 mg Lyophilized Powder Vial 129.89 - 227.63 129.89 293. Felodipine 10 mg MR Tablet 6.19 - 12.00 11.00 294. Felodipine 5 mg MR Tablet 1.81 - 11.00 7.35 295. Fenofibrate 160 mg Tablet 19.25 - 32.31 29.50 296. Fenofibrate 200 mg Capsule 5.25 - 15.38 13.40 297. Fentanyl 50mcg/mL, 10mL Ampule 250.00 - 465.00 267.50 298. Fentanyl 50mcg/mL, 2mL Ampule 53.44 - 187.34 59.35 299. Ferrous Salt (equiv. to 15 mg elemental iron/0.6 17.05 - 34.35 24.00 mL), 15 mL Drops 300. Ferrous Salt (equiv. to 30 mg elemental iron/5 18.75 - 28.00 20.49 mL), 60 mL Syrup 301. Ferrous Salt equiv. to 60 mg elemental iron Tablet 0.59 - 3.00 2.25 302. Ferrous Sulfate + Folic Acid 60 mg elemental iron 1.90 - 3.50 3.20 + 400 mcg folic acid Capsule

Health facilities may have a price variation up to 10% above the DPRI to account for inflation 2019 DPRI |Seventh Edition 16 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 303. Ferro us Sulfate + Folic Acid 60 mg elemental iron 0.51 - 3.40 0.60 + 400 mcg folic acid Film coated tablet 304. Ferrous Sulfate + Folic Acid 60 mg elemental iron 0.59 - 2.88 0.66 + 400 mcg folic acid Tablet 305. Ferrous Sulfate 15 mg elemental iron/0.6 mL, 15 14.68 - 24.00 23.25 mL Drops 306. Ferrous Sulfate 30 mg elemental iron/5 mL, 60 19.64 - 26.50 19.64 mL Syrup 307. Ferrous Sulfate 60 mg elemental iron Tablet 0.63 - 3.50 2.50 308. Filgrastim 150 mcg/0.6 mL Vial 899.90 - 979.00 899.90 309. Filgrastim 300 mcg/0.5 mL Pre-filled syringe 950.00 - 1,428.00 1,250.00 310. Filgrastim 300 mcg/1.2 mL Vial 948.00 - 2,879.00 1,100.00 311. Filgrastim 300 mcg/mL Vial 739.00 - 1,692.85 1,026.69 312. Finasteride 5 mg Tablet 7.38 - 38.00 9.32 313. Fluconazole 150 mg Capsule 17.86 - 210.00 70.00 314. Fluconazole 2 mg/mL, 100 mL Vial 103.22 - 1,175.00 386.33 315. Fluconazole 200 mg Capsule 80.00 - 370.00 278.00 316. Fluconazole 50 mg Capsule 39.00 - 115.65 78.00 317. Fluorescein 10%, 5 mL Ampule 506.42 - 6,077.00 506.42 318. Fluorouracil 50 mg/mL, 10 mL Vial 69.18 - 112.00 78.50 319. Fluoxetine 20 mg Capsule 4.11 - 37.87 4.11 320. Flupentixol 20 mg/mL, 1 mL Ampule 350.00 - 386.93 350.00 321. Fluphenazine (as Decanoate) 25 mg/mL, 1 mL 54.95 - 400.00 84.98 Ampule 322. Fluphenazine (as Decanoate) 25 mg/mL, 10 mL 91.00 - 306.00 140.00 Vial 323. Fluticasone (as propionate) + Formeterol (as 1,175.46 - 1,175.46 fumarate dihydrate) 125 mcg/5 mcg X 120 1,366.81 actuations Inhalation 324. Fluticasone + Salmeterol 100 mcg + 50 mcg x 60 389.85 - 613.90 389.85 doses Dry Powder Inhaler 325. Fluticasone + Salmeterol 125 mcg + 25 mcg x 120 175.00 - 355.00 228.75 doses Metered Dose Inhaler

Health facilities may have a price variation up to 10% above the DPRI to account for inflation

2019 DPRI |Seventh Edition 17 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 326. Fluticasone + Salmeterol 250 mcg + 25 mcg x 120 172.00 - 550.00 300.00 doses Metered Dose Inhaler 327. Fluticasone + Salmeterol 250 mcg + 50 mcg x 60 386.02 - 420.00 386.02 doses Dry Powder Inhaler 328. Fluticasone + Salmeterol 500 mcg + 50 mcg x 60 462.00 - 1,186.50 463.98 doses Dry Powder Inhaler 329. Fluticason e + Salmeterol 50mcg + 25mcg x 120 140.00 - 261.00 174.00 doses Metered Dose Inhaler 330. Fluticasone 0.05% dose x 120 doses Nasal 394.00 - 430.00 412.00 Aqueous Solution 331. Folic Acid 5 mg Capsule 1.87 - 6.00 3.53 332. Folic Acid 5 mg Tablet 1.50 - 4.60 2.68 333. Fondaparinux 2.5 mg/0.5 mL Solution 1,120.00 - 1,120.00 3,800.00 334. Formoterol 12 mcg dry powder for inhalation - 17.16 335. Fosfomycin 3 g Sachet 400.00 - 435.00 400.00 336. Furosemide 10 mg/mL, 2 mL Ampule 4.98 - 27.00 6.33 337. Furosemide 20 mg Tablet 0.59 - 10.00 1.30 338. Furosemide 40 mg Tablet 0.45 - 2.30 1.80 339. Fusidate Sodium/Fusidic Acid Cream 2%, 5 g 50.89 - 286.43 258.81 Tube 340. Fusidate Sodium/Fusidic Acid Ointment 2%, 15 g 105.00 - 387.00 150.00 Tube G 341. Gabapentin 100 mg Capsule 4.35 - 25.30 5.68 342. Gabapentin 300 mg Capsule 5.90 - 25.10 6.48 343. Gadoteric acid 0.5 mmol/mL Solution for - 2,860.00● Injection, 10 mL glass Vial 344. Gadobutrol 1.0 mmol/mL, 5 mL Pre-filled 2,050.00 - 2,050.00 syringe 2,500.00 345. Ganciclovir (as sodium) 500 mg vial - 1,826.47

The Reference Price was based on the Maximum Wholesale Price (MWP) plus Value-Added-Tax (VAT) (excluded from the maximum 10% inflationary cost) ● The Reference Price was based on the proposed list price of the pharmaceutical company upon its inclusion in the Philippine National Formulary (excluded from the maximum 10% inflationary cost) Health facilities may have a price variation up to 10% above the DPRI to account for inflation

2019 DPRI |Seventh Edition 18 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 346. Gemcitabine 1 g Vial 2,595.00 - 2,995.00 3,250.00 347. Gemcitabin e 200 mg Vial 650.00 - 875.50 735.00 348. Gentamicin 40 mg/mL, 2 mL Ampule 2.98 - 30.00 4.29 349. Gliclazide 30 mg MR Tablet 1.50 - 6.00 2.93 350. Gliclazide 60 mg MR Tablet 2.65 - 14.88 9.88 351. Gliclazide 80 mg Tablet 2.50 - 18.50 3.17 352. Glucose (Dextrose) 50%, 50 mL Vial 24.22 - 68.00 24.22 353. Glyceryl Trinitrate (Nitroglycerine) 1 mg/mL, 10 400.00 - 948.00 400.00 mL Ampule 354. Goserelin (as acetate) 3.6 mg depot solution, pre- - 4,613.06 filled syringe 355. Goserelin (as acetate) 10.8 mg depot solution, pre- - 15,767.24 filled syringe H 356. Haloperidol 5 mg Tablet 2.78 - 23.78 3.40 357. Hemodialysis Solution 5 gallon (concentrate), 5 L 175.00 - 195.00 175.00 Drum 358. Heparin (as Sodium) 1000 IU/mL, 5 mL Vial 42.89 - 295.00 48.83 359. Heparin (as Sodium) 5000 IU/mL, 5 mL Vial 141.12 - 250.00 149.89 360. Human Recombinant Tissue Type Plasminogen- - 30,536.02 Activator (Alteplase) 50 mg powder 361. Hydralazine 20 mg/mL, 1 mL Ampule 13.89 - 230.00 43.17 362. Hydrocortisone 100 mg powder, Vial 17.00 - 110.00 21.06 363. Hydrocortisone 125 mg/mL, 2 mL Vial 62.11 - 370.00 236.03 364. Hydrocortisone 250 mg powder, Vial 20.49 - 195.00 61.06 365. Hydrocortisone 50 mg/mL, 2 mL Vial 131.00 - 190.00 150.00 366. Hydrocortisone Cream 1%, 10 g Tube 75.00 - 110.08 102.00 367. Hydrocortisone Cream 1%, 5 g Tube 98.00 - 150.00 110.00 368. Hydrogen Peroxide 3%, 120 mL Bottle 15.00 - 25.00 17.13 369. Hydroxyethyl Starch 6%, 500 mL Bottle 300.00 - 784.00 432.50

2019 DPRI |Seventh Edition 19 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 370. Hydroxyurea 500 mg Capsule 15.56 - 25.00 17.00 371. Hydroxyzine 25 mg Tablet 4.16 - 22.98 4.16 372. Hyoscine (as N-butyl bromide) 10 mg Tablet 2.40 - 6.10 4.74 373. Hyoscine (as N-butyl bromide) 20 mg/mL, 1 mL 13.23 - 62.00 19.21 Ampule 374. Hypromellose Eye Drops Solution 5 mg/mL, 10 122.00 - 138.75 122.00 mL Bottle 375. Hypromellose Ophthalmic Solution 0.3%, 10 mL 126.00 - 150.00 126.00 Bottle I 376. I.V. Fluids, 0.9% Sodium Chloride 1 L Bottle 33.12 - 75.42 40.94 377. I.V. Fluids, 0.9% Sodium Chloride 1 L Glass 76.92 - 124.00 76.92 Bottle 378. I.V. Fluids, 0.9% Sodium Chloride 10 mL Ampule 11.10 - 11.50 11.10 379. I.V. Fluids, 0.9% Sodium Chloride 100 mL Bag 60.00 - 65.00 60.00 380. I.V. Fluids, 0.9% Sodium Chloride 100 mL Bottle 54.50 - 100.00 54.50 381. I.V. Fluids, 0.9% Sodium Chloride 20 mL Ampule 21.00 - 26.93 21.00 382. I.V. Fluids, 0.9% Sodium Chloride 50 mL Bottle 18.88 - 44.80 24.48 383. I.V. Fluids, 0.9% Sodium Chloride 500 mL Bottle 33.50 - 95.00 44.30 384. I.V. Fluids, 0.9% Sodium Chloride 500 mL Glass 82.74 - 110.88 82.74 Bottle 385. I.V. Fluids, 10% Dextrose in Water 1 L Bottle 43.34 - 57.95 45.00 386. I.V. Fluids, 10% Dextrose in Water 500 mL Bottle 38.32 - 67.88 42.90 387. I.V. Fluids, 5% Dextrose in 0.3% Sodium 38.43 - 65.89 43.78 Chloride 1 L Bottle 388. I.V. Fluids, 5% Dextrose in 0.3% Sodium 36.68 - 79.63 42.84 Chloride 500 mL Bottle 389. I.V. Fluids, 5% Dextrose in 0.3% Sodium 81.13 - 100.00 81.13 Chloride 500 mL Glass Bottle 390. I.V. Fluids, 5% Dextrose in 0.9% Sodium 36.34 - 83.12 44.83 Chloride 1 L Bottle 391. I.V. Fluids, 5% Dextrose in 0.9% Sodium 39.43 - 72.00 44.71 Chloride 500 mL Bottle

Health facilities may have a price variation up to 10% above the DPRI to account for inflation

2019 DPRI |Seventh Edition 20 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 392. I.V. Fluids, 5% Dextrose in Lactated Ringer's 1 L 33.32 - 78.31 42.33 Bottle 393. I.V. Fluids, 5% Dextrose in Lactated Ringer's 1 L 110.00 - 132.00 110.00 Glass Bottle 394. I.V. Fluids, 5% Dextrose in Lactated Ringer's 500 39.88 - 58.88 44.39 mL Bottle 395. I.V. Fluids, 5% Dextrose in Water 1 L Bottle 33.88 - 83.12 44.63 396. I.V. Fluids, 5% Dextrose in Water 1 L Glass 84.56 - 126.00 84.56 Bottle 397. I.V. Fluids, 5% Dextrose in Water 250 mL Bottle 43.79 - 96.32 53.22 398. I.V. Fluids, 5% Dextrose in Water 250 mL Glass 86.69 - 96.10 86.69 Bottle 399. I.V. Fluids, 5% Dextrose in Water 500 mL Bottle 36.68 - 67.88 42.11 400. I.V. Fluids, 5% Dextrose in Water 500 mL Glass 76.92 - 119.56 76.92 Bottle 401. I.V. Fluids, Acetated Ringer's Solution 1 L Bottle 95.00 - 230.00 95.00 402. I.V. Fluids, Balanced Multiple Maintenance 37.39 - 84.62 44.80 Solution with 5% Dextrose for Adult 1 L Bottle 403. I.V. Fluids, Balanced Multiple Maintenance 37.50 - 83.08 42.34 Solution with 5% Dextrose for Pedia 500 mL Bottle 404. I.V. Fluids, Balanced Multiple Replacement 44.74 - 52.33 45.00 Solution with 5% Dextrose 1 L Bottle 405. I.V. Fluids, Lactated Ringer's Solution 1 L Bottle 33.32 - 83.12 43.45 406. I.V. Fluids, Lactated Ringer's Solution 500 mL 38.33 - 58.88 44.34 Bottle 407. Ibuprofen 100 mg/5 mL, 60 mL Bottle 22.62 - 66.15 37.99 408. Ibuprofen 200 mg Tablet 0.55 - 6.00 1.05 409. Ibuprofen 200 mg/5 mL, 60 mL Bottle 39.00 - 105.85 60.50 410. Ibuprofen 400 mg Tablet 0.80 - 6.15 1.00 411. Idarubicin 5 mg Vial 6,531.74 - 6,531.74 7,041.21 412. Ifosfamide 1 g Vial 1,100.00 - 1,100.00 1,830.00

Health facilities may have a price variation up to 10% above the DPRI to account for inflation

2019 DPRI |Seventh Edition 21 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 413. Imatinib 100 mg Tablet 1,347.53 - 1,347.53 1,347.53 414. Immunoglobulin, Antithymocyte (ATG) (rabbit) - 13,108.61 25 mg/5 mL vial 415. Immunoglobulin, Hepatitis B (human) 0.5 mL 1,163.00 - 1,163.00 Vial 1,925.00 416. Immunoglobulin, Normal, Human (IGIV) 50 1,532.00 - 1,532.00 mg/mL, 10 mL Vial 1,650.00 417. Immunoglobulin, Normal, Human (IGIV) 50 4,443.44 - 10,450.00 mg/mL, 100 mL Vial 17,500.00 418. Immunoglobulin, Normal, Human (IGIV) 50 4,689.00 - 5,284.00 mg/mL, 50 mL Vial 6,668.00 419. Immunoglobulin, Rabies (human) 150 IU/mL, 2 1,200.00 - 3,060.00 mL Vial 4,000.00 420. Immunoglobulin, Tetanus (Human) 250 IU/mL, 640.00 - 925.00 640.00 1 mL Ampule 421. Immunoglobulin, Tetanus (Human) 250 IU/mL, 645.00 - 914.28 700.00 1 mL Pre-filled syringe 422. Immunoglobulin, Tetanus (Human) 250 685.00 - 950.00 685.00 units/mL, 1 mL Vial 423. Immunoglobulin, Tetanus (Human) 250 600.00 - 699.00 600.00 units/mL, 2 mL Vial 424. Indacaterol (as maleate) + glycopyrronium (as 69.42 - 69.42 69.42 bromide) 110 mcg/50 mcg powder Hard Capsule 425. Insulin, Biphasic Isophane Human 70/30 95.00 - 623.44 118.00 (recombinant DNA) 70% isophane suspension + 30% soluble insulin in 100 IU/mL, 10 mL Vial 426. Insulin, Isophane Human 100 IU/mL, 10 mL Vial 95.00 - 200.00 119.00 427. Insulin, Regular (Recombinant DNA, human) 100 95.00 - 700.00 135.00 IU/mL, 10 mL Vial 428. Intraocular Irrigating Solution (balanced salt 190.00 - 500.00 190.00 solution) 500 mL Bottle 429. Iohexol 300 mg iodine/mL, 50 mL Vial 773.95 - 1,129.48 1,049.44 430. Iohexol 350 mg iodine/mL, 50 mL Vial 1,298.88 - 1,298.88 1,458.22

2019 DPRI |Seventh Edition 22 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 431. Iopamidol 300 mg/mL, 100 mL Vial 2,300.00 - 2,300.00 3,450.00 432. Iopamidol 612 mg/mL equiv. to 300 mg iodine, 983.12 - 2,200.00 1,308.72 100 mL Vial 433. Iopamidol 612 mg/mL equiv. to 300 mg iodine, 596.33 - 2,450.00 708.67 50 mL Vial 434. Iopamidol 755 mg/mL equiv. to 370 mg iodine, 1,319.00 - 1,721.50 100 mL Vial 2,750.00 435. Iopamidol 755 mg/mL equiv. to 370 mg iodine, 890.00 - 1,008.00 890.00 50 mL Bottle 436. Iopamidol 755 mg/mL equiv. to 370 mg iodine, 890.00 - 1,165.00 1,007.00 50 mL Vial 437. Iopromide 300 mg/mL equiv. to 623 mg iodine, 1,000.00 - 1,000.00 50 mL Vial 1,400.00 438. Iopromide 370 mg/mL equiv. to 769 mg iodine, 1,900.00 - 1,900.00 100 mL Vial 2,100.00 439. Iopromide 370 mg/mL equiv. to 769 mg iodine, 1,200.00 - 1,200.00 50 mL Vial 1,700.00 440. Ioversol 636 mg/mL equiv. to 300 mg/mL 1,200.00 - 1,200.00 iodine, 50 mL Vial 1,300.00 441. Ioversol 741 mg/mL equiv. to 350 mg/mL 1,300.00 - 1,300.00 iodine, 50 mL Vial 1,650.00 442. Ipratropium + Salbutamol 500 mcg + 2.5 mg x 6.98 - 31.00 9.89 2.5 mL (unit dose) Respiratory Solution 443. Ipratropium 250 mcg/mL, 2 mL (unit dose) 75.00 - 84.00 79.10 Respiratory Solution 444. Irbesartan + Hydrochlorothiazide 150 mg + 12.5 4.24 - 20.70 9.90 mg Tablet 445. Irbesartan 150 mg Tablet 2.78 - 19.40 3.75 446. Irbesartan 300 mg Tablet 7.29 - 29.40 8.33 447. Irinotecan 100 mg/5 mL concentrate Vial 3,299.00 - 3,740.00 3,750.00 448. Iron Sucrose 20 mg/mL, 5 mL Ampule 93.22 - 380.00 131.86 449. Isoflurane 100 mL Bottle 544.32 - 1,974.33 1,409.11 450. Isoniazid + Rifampicin + Ethambutol 75 mg + 4.10 - 8.00 4.10 150 mg + 275 mg Tablet

Health facilities may have a price variation up to 10% above the DPRI to account for inflation

2019 DPRI |Seventh Edition 23 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 451. Isoniazid + Rifampicin + Pyrazinamide + 4.10 - 10.00 7.70 Ethambutol 75 mg + 150 mg + 400 mg + 275 mg Tablet 452. Isoniazid + Rifampicin 75 mg + 150 mg Tablet 4.46 - 5.50 4.46 453. Isoniaz id 200 mg/5 mL, 120 mL Syrup 34.52 - 78.00 72.00 454. Isoniazid 300 mg Tablet 0.90 - 9.47 0.90 455. Isosorbide Dinitrate 1 mg/mL, 10 mL Ampule 131.78 – 544.01 131.78 456. Isosorbide Dinitrate 10 mg Tablet 0.78 - 13.47 8.88 457. Isosorbide Dinitrate 5 mg Sublingual Tablet 2.00 - 18.22 8.00 458. Isosorbide -5-Mononitrate 30 mg MR Capsule 7.92 - 13.04 7.92 459. Isosorbide -5-Mononitrate 30 mg MR Tablet 5.70 - 16.00 11.10 460. Isosorbide -5-Mononitrate 60 mg MR Tablet 4.00 - 12.00 7.21 461. Isotonic Electrolyte Sodium Chloride 1 L Bottle 120.00 - 250.00 120.00 462. Isoxsuprine Hydrochloride 10 mg Tablet 1.98 - 19.50 4.48 463. Isoxsuprine Hydrochloride 5 mg/mL, 2 mL 147.43 - 290.25 169.00 Ampule 464. Itraconazole 100 mg Capsule 39.22 - 76.00 45.00 K 465. Ketamine 50 mg/mL, 10 mL Vial 299.00 - 1,344.00 455.61 466. Ketoconazole 2%, 15 g aluminum tube 70.00 - 140.00 91.50 467. Ketorolac 30 mg/mL, 1mL Ampule 7.12 - 108.00 15.87 L 468. Lactulose 3.3 g/5 mL, 120 mL Syrup 56.10 - 236.00 108.33 469. Lagundi 300 mg Tablet 1.30 - 2.52 1.85 470. Lagundi 300 mg/5 mL, 120 mL Syrup 50.00 - 81.37 74.88 471. Lagundi 300 mg/5 mL, 60 mL Syrup 37.50 - 78.00 54.50 472. Lagundi 600 mg Tablet 1.87 - 5.88 3.55 473. Lamotrigine 100 mg Tablet 7.42 - 20.00 18.25 474. Lamotrigine 50 mg Tablet 5.37 - 14.00 13.50 475. Lansoprazole 30 mg Capsule 14.95 - 32.00 19.78 476. L- Asparaginase 10,000 IU Vial 1,528.00 - 1,689.00 2,108.00

Adjusted HPR Flexibility for GIDA based on MWP plus VAT Health facilities may have a price variation up to 10% above the DPRI to account for inflation 2019 DPRI |Seventh Edition 24 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 477. Le trozole 2.5 mg Tablet 53.22 - 56.33 54.78 478. Leuproreline 11.25 mg powder depot solution 11,319.00 - 11,319.00 Vial + Syringe 13,800.00 479. Levodopa + Carbidopa 100 mg + 25 mg Tablet 14.35 - 50.00 19.80 480. Levodopa + Carbidopa 250 mg + 25 mg Tablet 27.44 - 35.77 29.40 481. Levofloxacin 500 mg Tablet 3.60 - 48.00 8.00 482. Levofloxacin 750 mg Tablet 10.00 - 76.00 13.72 483. Levofloxacin 5 mg/mL, 100 mL Vial 78.33 - 999.90 122.12 484. Levofloxacin 5 mg/mL, 150 mL Vial - 1,356.00● 485. Levothyroxine 100 mcg Tablet 2.80 - 8.46 6.80 486. Levothyroxine 150 mcg Tablet 11.00 - 11.00 11.00 487. Levothyroxine 50mcg Tablet 1.89 - 4.62 3.60 488. Lidocaine 10%, 50 mL Spray 2,000.00 - 2,000.00 2,410.00 489. Lidocaine 2%, 1.8mL w/ epinephrine Carpule 12.79 - 46.44 19.75 490. Lidocaine 2%, 20 mL Ampule 9.32 - 33.00 11.00 491. Lidocaine 2%, 5 mL Ampule 8.11 - 28.77 12.00 492. Lidocaine 2%, 50 mL Vial 34.00 - 65.00 38.00 493. Linezolid 600 mg Tablet - 3,961.69● 494. Linezolid 2 mg/mL (600 mg/300 mL) Solution 3,850.00 - 3,850.00 4,100.00 495. Lipids 10%, 500 mL Bottle 800.00 - 1,044.42 800.00 496. Lipids 20%, 100 mL Bottle 860.00 - 1,222.00 860.00 497. Lipids 20%, 250 mL Bottle 800.00 - 1,300.00 800.00 498. Lithium Carbonate 450 mg MR Tablet 4.33 - 12.00 4.33 499. Loperamide Hydrochloride 2 mg Capsule 0.35 - 5.50 1.55 500. Loratadine 10 mg Tablet 0.83 - 10.51 1.49 501. Loratadine 5 mg/5 mL, 30 mL Syrup 43.04 - 43.04 43.04 502. Losartan + Hydrochlorothiazide 50mg +12.5 mg 0.76 - 15.77 1.69 Tablet

2019 DPRI |Seventh Edition 25 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 503. Losartan 100 mg Tablet 0.79 - 9.60 2.76 504. Losartan 50 mg Tablet 0.55 - 10.00 0.79 M 505. Magnesium Sulfate 250 mg/mL, 10 mL Ampule 11.70 - 63.49 56.68 506. Magnesium Sulfate 250 mg/mL, 10 mL Vial 24.11 - 43.33 24.11 507. Ma gnesium Sulfate 250 mg/mL, 20 mL Vial 26.00 - 55.00 26.00 508. Mannitol 20%, 250 mL Bottle 112.22 - 168.00 112.22 509. Mannitol 20%, 500 mL Bottle 71.79 - 370.00 93.22 510. Mebendazole 100 mg/5 mL, 60 mL Suspension 14.20 - 25.00 17.93 511. Mebendazole 500 mg Tablet 1.96 - 3.85 3.11 512. Mecobalamin 500 mcg Tablet 7.94 - 14.07 12.41 513. Mecobalamin 500 mcg/mL, 1 mL Ampule 79.98 - 246.22 187.63 514. Mefenamic Acid 250 mg Capsule 0.62 - 4.85 0.70 515. Mefenamic Acid 250 mg Tablet 1.00 - 3.28 1.90 516. Mefenamic Acid 500 mg Capsule 0.58 - 8.30 1.39 517. Mefenamic Acid 500 mg Tablet 0.52 - 10.60 1.33 518. Mercaptopurine 50 mg Tablet 18.00 - 20.00 18.00 519. Meropenem 1 g Vial 116.00 - 1,800.00 159.38 520. Meropenem 500 mg Vial 73.22 - 435.00 101.18 521. Mesna 100 mg/mL, 4 mL Ampule 148.80 - 160.00 160.00 522. Metformin Hydrochloride 500 mg Tablet 0.39 - 3.70 0.63 523. Metformin Hydrochloride 850 mg Tablet 4.80 - 7.00 5.20 524. Methotrexate 2.5 mg Tablet 7.06 - 13.88 7.06 525. Methotrexate 25 mg/mL, 2 mL Vial 117.00 - 200.00 138.00 526. Methyldopa 250 mg Tablet 5.30 - 16.90 9.45 527. Methylergometrine 200 mcg/mL, 1 mL Ampule 6.99 - 63.00 14.06 528. Methylprednisolone 1 g lyophilized powder Vial 2,375.00 - 2,375.00 2,850.00 529. Methylprednisolone 1 g/16 mL + Diluent Vial 1,800.00 - 2,484.01 4,900.00 530. Methy lprednisolone 125 mg/mL, 2 mL + diluent 620.00 - 730.00 620.00 Vial

Health facilities may have a price variation up to 10% above the DPRI to account for inflation 2019 DPRI |Seventh Edition 26 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 531. Methylprednisolone 16 mg Tablet 4.10 - 22.00 7.88 532. Methylprednisolone 4 mg Tablet 4.10 - 10.00 5.25 533. Methylprednisolone 40 mg ( single dose) Vial 247.79 - 700.00 289.93 534. Methylprednisolone 500 mg lyophilized powder 1,150.00 - 1,150.00 Vial 1,250.00 535. Methylprednisolone 500 mg/8.0 mL + diluent vial 1,250.00 - 1,250.00 Vial 3,796.51 536. M ethylprednisolone 500mg/7.7mL + Diluent Vial 1,087.15 - 1,087.15 2,500.00 537. Metoclopramide 10 mg Tablet 0.35 - 6.80 2.15 538. Metoclopramide 5 mg/5 mL, 60 mL Syrup 13.00 - 22.40 17.93 539. Metoclopramide 5 mg/mL, 2 mL Ampule 2.43 - 36.00 3.98 540. Metoprolol (as Tartrate) 100 mg Tablet 0.78 - 4.50 1.65 541. Metoprolol (as Tartrate) 50 mg Tablet 0.48 - 3.00 1.10 542. Metronidazole 125 mg/5 mL, 60 mL Suspension 13.75 - 85.00 19.64 543. Metronidazole 5 mg/mL, 100 mL Vial 11.11 - 40.00 14.94 544. Metronidazole 500 mg Tablet 0.65 - 3.65 1.25 545. Midazolam 1 mg/mL, 5 mL Ampule 69.00 - 103.69 75.00 546. Midazolam 1 mg/mL, 5 mL Vial 71.00 - 145.38 71.00 547. Midazolam 5 mg/mL, 2 mL Ampule 74.43 - 159.00 74.43 548. Midazolam 5 mg/mL, 3 mL Ampule 69.78 - 215.84 103.28 549. Midazolam 5 mg/mL,1 mL Ampule 49.98 - 152.00 71.33 550. Modified Fluid Gelatin (Formerly Polymerisate of 500.00 - 669.00 500.00 Degraded Succinylated Gelatin) 3%, 500 mL Bottle 551. Modified Fluid Gelatin (Formerly Polymerisate of 515.00 - 954.00 515.00 Degraded Succinylated Gelatin) 4% solution, 500 mL Bottle 552. Monobasic Sodium Phosphate, Dibasic Sodium 172.88 - 230.00 205.50 Phosphate 19 g/ 7 g solution per 133 mL Bottle 553. Monobasic Sodium Phosphate, Dibasic Sodium 210.00 - 245.00 226.50 Phosphate 48 g/18 g per 100 mL solution, 45 mL Bottle 554. Montelukast 10 mg Tablet 5.00 - 26.00 8.67

Health facilities may have a price variation up to 10% above the DPRI to account for inflation

2019 DPRI |Seventh Edition 27 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 555. Montelukast 4 mg Chewable Tablet 2.98 - 19.35 6.93 556. Montelukast 4 mg Sachet 2.70 - 16.15 7.50 557. Montelukast 5 mg Chewable Tablet 3.21 - 17.69 8.43 558. Morphine (As Sulfate) 10 mg MR Tablet - 11.29 559. Morphine (As Sulfate) 10 mg Tablet 20.00 - 24.24 20.00 560. Morphine (As Sulfate) 10 mg/mL,1 mL Ampule 43.00 - 90.72 51.25 561. Morphine (As Sulfate) 30 mg MR Tablet - 29.32 562. Morphine (As Sulfate) 60 mg MR tablet - 78.03 563. Morphine (As Sulfate) 30 mg Tablet 49.00 - 66.05 49.00 564. Moxifloxacin Hydrochloride 5 mg/mL (0.5% - 543.75● w/v) sterile ophthalmic solution, 5 mL Bottle 565. Multivitamins for adults Capsule 0.71 - 8.00 1.35 566. Multivitamins for adults Tablet 0.79 - 5.00 1.90 567. Multivitamins per 1 mL ,15 mL Drops 12.80 - 52.50 26.50 568. Multivitamins per 5 mL, 120 mL Syrup 29.20 - 88.00 55.00 569. Multivitamins per 5 mL, 60 mL Syrup 12.80 - 49.99 19.89 570. Mupirocin Cream 2%, 15 g Tube 133.44 - 170.00 133.44 571. Mupirocin Cream 2%, 5 g Sachet 52.44 - 190.00 65.31 572. Mupirocin Ointment 2%, 15 g Tube 43.22 - 184.33 113.44 573. Mupirocin Ointment 2%, 5 g Tube 44.33 - 185.00 55.61 574. M ycophenolate Mofetil 500 mg Tablet 44.80 - 65.00 55.00 575. Mycophenolic Acid (as Mycophenolate Sodium) - 65.76 360 mg tablet N 576. Nalbuphine 10 mg/mL, 1 mL Ampule 45.00 - 100.00 52.33 577. Naloxone 400 mcg/mL, 1 mL Ampule 209.22 - 478.88 263.22 578. Naproxen Sodium 550 mg Tablet 1.73 - 16.50 3.30

2019 DPRI |Seventh Edition 28 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 579. Neomycin + Polymyxin B + Fluocinolone 180.00 - 294.34 200.00 Acetonide Ear Drops 3.5 mg neomycin + 10,000 units polymyxin B + 0.025% floucinolone acetonide/mL, 5 mL Bottle 580. Neostigmine 500 mcg/mL, 1 mL Ampule 90.55 - 125.34 118.75 581. Nepafenac 1 mg/mL, 5 mL Bottle 553.59 - 615.10 553.59 582. Nicardipine 1 mg/mL, 10 mL Ampule 110.00 - 1,734.00 249.20 583. Nicardipine 1 mg/mL, 2 mL Ampule 62.99 - 122.12 89.78 584. Nifedipine 10 mg Capsule 2.83 - 4.90 3.79 585. Nifedipine 30 mg MR Tablet 29.11 - 38.00 29.11 586. Nimodipine 30 mg Tablet - 30.82 587. Ni trofurantoin 100 mg Capsule 7.80 - 52.37 7.80 588. Norepinephrine 1 mg/mL, 10 mL Ampule 945.85 - 1,550.00 1,200.00 589. Norepinephrine 1 mg/mL, 2 mL Ampule 81.23 - 500.00 98.88 590. Norepinephrine 1 mg/mL, 4 mL Ampule 143.22 - 890.00 262.00 591. Norepinephrine 2 mg/mL, 4 mL Ampule - 1,650.00● 592. Nystatin 100,000 units/mL, 30 mL Suspension 91.36 - 248.00 157.63 O 593. Octreotider 100 mcg/mL, 1 mL Ampule 669.50 - 720.00 669.50 594. Octreotide 500 mcg/mL, 1 mL Ampule 3,841.00 - 3,841.00 4,268.26 595. Ofloxacin 200 mg Tablet 3.50 - 4.90 3.90 596. Ofloxacin Ear Drops 0.3%, 5 mL Bottle 95.00 - 280.00 195.00 597. Ofloxacin Eye Drops 0.3%, 5 mL Bottle 125.33 - 250.00 168.00 598. Olanzapine 10 mg Orodispersible tab 9.00 - 83.00 32.00 599. Olanzapine 10 mg Tablet 3.12 - 59.85 6.11 600. Olanz apine 5 mg Tablet 5.00 - 28.75 5.00 601. Omeprazole 20 mg Capsule 0.69 - 18.00 0.93 602. Omeprazole 40 mg Capsule 5.50 - 35.45 8.70

2019 DPRI |Seventh Edition 29 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 603. Omeprazole 40 mg powder vial + 10 mL solvent 21.89 - 210.00 29.12 Ampule 604. Ondansetron (as Hydrochloride) 2 mg/mL, 2 mL 127.50 - 420.00 195.75 Ampule 605. Ondansetron (as Hydrochloride) 2 mg/mL, 4 mL 20.00 - 275.00 129.88 Ampule 606. Ondansetron (as Hydrochloride) 8 mg Tablet 70.00 - 150.00 80.00 607. Oral Rehydration Salts (ORS 75-replacement) 20.5 3.31 - 6.85 4.25 g Sachet 608. Oral Rehydration Salts (ORS 75-replacement) 4.1 3.60 - 5.00 3.60 g Sachet 609. Or al Rehydration Salts (ORS 75-replacement) 2.99 - 7.55 6.10 5.125 g Sachet 610. Oral Rehydration Salts (ORS 75-replacement) 75 2.95 - 4.80 3.19 replacement 2.17 g Sachet 611. Oxacillin 500 mg Vial 15.22 - 140.00 18.89 612. Oxaliplatin 5 mg/mL concentrate solution, 10 mL 2,000.00 - 2,369.00 Vial 2,700.00 613. Oxaliplatin 5 mg/mL concentrate solution, 20 mL 1,622.00 - 3,747.50 Vial 6,256.00 614. Oxaliplatin 50 mg powder Vial 894.44 - 2,770.00 1,493.66 615. Oxycodone 10 mg Tablet - 129.75 616. Oxycodone 10 mg/mL, 1 mL Ampule - 618.69 617. Oxycodone 10 mg/mL, 2 mL Ampule - 1,034.32 618. Oxycodone 20 mg Tablet 236.50 - 286.27 236.50 619. Oxycodone 5 mg Capsule 124.11 - 136.84 124.11 620. Oxycodone Hydrochloride/Naloxone - 89.71 Hydrochloride 5 mg + 2.5 mg Prolonged Release Tablet 621. Oxycodone (as hydrochloride) + Naloxone (as - 81.67 hydrochloride) 10 mg + 5 mg prolonged-release tablet

2019 DPRI |Seventh Edition 30 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 622. Oxycodone (as hydrochloride) + Naloxone (as - 161.06 hydrochloride) 20 mg + 10 mg prolonged-release tablet 623. Oxycodone (as hydrochloride) + Naloxone (as - 272.76 hydrochloride) 40 mg + 20 mg prolonged-release tablet 624. Oxytocin 10 IU/mL, 1 mL Ampule 5.89 - 76.92 7.34 P 625. Paclitaxel 6 mg/mL, 17 mL Vial 1,548.00 - 1,965.25 2,050.00 626. Paclitaxel 6 mg/mL, 25 mL Vial 3,878.00 - 5,880.00 10,104.00 627. Paclitaxel 6 mg/mL, 43.4 mL Vial 3,402.00 - 6,259.00 7,799.60 628. Paclitaxel 6 mg/mL, 5 mL Vial 397.32 - 690.75 523.22 629. Paracetamol 10 mg/mL, 100 mL Vial 110.00 - 350.00 148.67 630. Paracetamol 10 mg/mL, 50 mL Vial 198.00 - 388.00 198.00 631. Paracetamol 100 mg/ml, 15 mL Drops 9.52 - 50.00 15.53 632. Paracetamol 120 mg/5 mL (125 mg/5 mL), 60 10.00 - 22.00 14.73 mL Bottle 633. Paracetamol 125 mg Suppository 10.33 - 65.00 17.33 634. Paracetamol 150 mg/mL, 2 mL Ampule 3.00 - 45.00 4.43 635. Paracetamol 250 mg Suppository 12.33 - 75.00 16.91 636. Paracetamol 250 mg/5 mL, 60 mL Bottle 9.52 - 95.72 16.62 637. Paracetamol 500 mg Tablet 0.19 - 2.50 0.29 638. Penicillin G Benzathine (benzathine 42.33 - 124.00 51.33 benzylpenicillin) 1,200,000 units Vial 639. Penicillin G Crystalline 1 MU Vial 3.89 - 16.92 6.36 640. Penicillin G Crystalline 5 MU Vial 12.23 - 25.00 16.15 641. Permethrin Lotion 5%, 60 mL Bottle 218.00 - 219.00 218.00 642. Pethidine 50 mg/mL, 2 mL Ampule 140.00 - 220.00 140.00 643. Phenobarbital 120 mg/mL (130 mg/mL), 1 mL 489.79 - 509.28 489.79 Ampule

The Reference Price was based on the Maximum Wholesale Price (MWP) plus Value-Added-Tax (VAT) (excluded from the maximum 10% inflationary cost) Health facilities may have a price variation up to 10% above the DPRI to account for inflation 2019 DPRI |Seventh Edition 31 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 644. Phe nobarbital 30 mg Tablet 2.88 - 3.00 2.88 645. Phenobarbital 60 mg Tablet 3.93 - 4.00 3.93 646. Phenytoin 100 mg Capsule 6.76 - 31.46 12.75 647. Phenytoin 50 mg/mL, 2 mL Ampule 53.44 - 680.00 93.22 648. Phytomenadione 10 mg/mL, 1 mL Ampule 13.00 - 50.00 16.78 649. Pi peracillin + Tazobactam 2 g + 250 mg Vial 36.00 - 580.00 73.22 650. Piperacillin + Tazobactam 4 g + 500 mg Vial 83.88 - 1,400.00 98.48 651. Potassium Chloride 2 mEq/mL, 20 mL Vial 10.50 - 59.14 22.36 652. Potassium Chloride 600 mg Tablet 9.50 - 32.60 11.00 653. Po tassium Chloride 750 mg durules (equiv. to 9.80 - 24.95 15.00 approximately 10 mEq) Tablet 654. Potassium Citrate 10 mEq Tablet 5.10 - 15.20 7.00 655. Povidone Iodine (Oral Antiseptic) 1%, 60 mL 54.89 - 89.00 89.00 Bottle 656. Povidone Iodine (Solution) 10%, 1 gallon Bottle 500.00 - 600.00 500.00 657. Povidone Iodine (Solution) 10%, 120 mL Bottle 49.95 - 99.73 49.95 658. Povidone Iodine (Solution) 10%, 60 mL Bottle 30.00 - 130.00 48.00 659. Povidone Iodine (Surgical Skin Cleanser) 7.5%, 1 585.00 - 595.00 585.00 gallon Bottle 660. Prednisolone Eye Drops 1%, 5 mL Bottle 130.00 - 260.00 167.00 661. Prednisone 10 mg Tablet 0.70 - 6.40 2.47 662. Prednisone 10 mg/5 mL, 60 mL Suspension 16.98 - 130.70 104.69 663. Prednisone 20 mg Tablet 2.60 - 7.10 4.04 664. Prednisone 5 mg Tablet 0.39 - 1.80 0.57 665. Propofol 10 mg/mL, 20 mL Ampule 47.22 - 626.00 63.12 666. Propofol 10 mg/mL, 20 mL Vial 47.22 - 452.00 58.00 667. Propofol 10 mg/mL, 50 mL Pre-filled syringe 480.00 - 598.00 480.00 668. Propofol 10 mg/mL, 50 mL Vial 365.00 - 659.00 540.00 669. Propr anolol 10 mg Tablet 1.00 - 12.52 6.00 670. Propranolol 40 mg Tablet 0.87 - 16.67 8.80 671. Propylthiouracil 50 mg Tablet 8.50 - 11.20 9.70 672. Pyrazinamide 250 mg/5 mL, 120 mL Suspension 60.71 - 90.00 82.04

Health facilities may have a price variation up to 10% above the DPRI to account for inflation 2019 DPRI |Seventh Edition 32 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 673. Pyridostigmine 60 mg Tablet 29.18 - 33.32 29.18 Q 674. Quetiapine (as Fumarate) 100 mg Tablet 22.58 - 54.00 32.25 675. Quetiapine (as Fumarate) 200 mg Tablet 22.50 - 80.10 34.00 676. Quetiapine (as Fumarate) 25 mg Tablet 19.80 - 23.59 20.00 677. Quetiapine (as Fumarate) 300 mg Tablet 47.00 - 85.00 54.75 R 678. Rabeprazole (as Sodium) 20 mg Tablet 15.72 - 35.00 15.72 679. Ranitidine 150 mg Tablet 0.61 - 5.00 0.72 680. Ranitidine 25 mg/mL, 2 mL Ampule 2.12 - 45.00 3.43 681. Ranitidine 300 mg Tablet 1.56 - 4.45 2.45 682. Remifentanil 1 mg Lyophilized powder - 1,500.00● 683. Remifentanil 2 mg Lyophilized powder - 3,000.00● 684. Rifampicin 200 mg/5 mL, 120 mL Suspension 103.57 - 208.05 162.00 685. Rifaximin 200 mg Tablet 63.20 - 69.20 63.20 686. Risperidone 1 mg Tablet 2.50 - 8.71 6.44 687. Risperidone 2 mg Orodispersible tab 33.00 - 48.00 41.13 688. Risperidone 2 mg Tablet 0.89 - 33.00 3.44 689. Risperidone 4 mg Tablet 19.80 - 92.00 90.40 690. Rituximab 10 mg/mL, 10 mL Vial - 10,957.79 691. Rituximab 10 mg/mL, 50 mL Vial - 53,394.20 692. Rocuronium 10 mg/mL, 5 mL Ampule 160.00 - 178.34 160.00 693. Rocuronium 10 mg/mL, 5 mL Vial 171.00 - 300.00 197.88 694. Rosuvastatin (as Calcium) 10 mg Tablet 2.77 - 21.00 4.61 695. Rosuvastatin (as Calcium) 20 mg Tablet 4.02 - 47.67 7.06 S 696. Sacubitril/Valsartan 50 mg Tablet - 56.25● 697. Sacubitril/Valsartan 100 mg Tablet - 56.25● 698. Sacubitril/Valsartan 200 mg Tablet - 56.25●

● The Reference Price was based on the proposed list price of the pharmaceutical company upon its inclusion in the Philippine National Formulary (excluded from the maximum 10% inflationary cost) The Reference Price was based on the Maximum Wholesale Price (MWP) plus Value-Added-Tax (VAT) (excluded from the maximum 10% inflationary cost) Health facilities may have a price variation up to 10% above the DPRI to account for inflation 2019 DPRI |Seventh Edition 33 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 699. Salbutamol 1 mg/mL, 2.5 mL (unit dose) Nebule 3.98 - 11.57 5.39 700. Salbutamol 100 mcg/dose x 200 doses Metered 57.22 - 140.00 85.84 Dose Inhaler 701. Salbutamol 2 mg/5mL, 60 mL Syrup 9.52 - 53.50 15.05 702. Salbutamol 2 mg/mL, 2.5 mL (unit dose) Nebule 3.98 - 11.54 8.00 703. Sambong 500 mg Tablet 1.80 - 7.80 6.00 704. Sertraline 50 mg Tablet 4.50 - 38.00 7.95 705. Serum, Anti-rabies (equine) 200 IU/mL, 5 mL 943.00 - 1,790.00 1,183.92 Vial 706. Serum, Anti-tetanus (ATS) (equine) 1500 IU/0.7 58.39 - 78.00 68.75 mL, 0.7 mL Ampule 707. Serum, Anti-tetanus (ATS) (equine) 1500 IU/mL, 55.44 - 115.00 65.00 1 mL Ampule 708. Serum, Anti-tetanus (ATS) (equine) 1500 IU/mL, 75.00 - 208.00 75.00 1.5 mL Ampule 709. Sevelamer Carbonate 800 mg Tablet - 38.79 710. Sevelamer Carbonate 800 mg powder for - 87.00● Suspension 711. Sevoflurane 250 mL Bottle 4,128.33 - 4,974.33 8,899.00 712. Silver Sulfadiazine Cream 1%, 15 g Tube 58.88 - 114.00 58.88 713. Silver Sulfadiazine Cream 1%, 25 g Tube 65.12 - 129.88 74.33 714. Silver Sulfadiazine Cream 1%, 500 g Jar 800.00 - 1,068.00 880.00 715. Simvastatin 20 mg Tablet 0.70 - 7.20 2.32 716. Simvastatin 40 mg Tablet 2.25 - 10.00 4.25 717. Sirolimus 0.5 mg tablet - 153.41 718. Sirolimus 1 mg Tablet - 208.01 719. Sodium Bicarbonate 1 mEq/ mL, 20 mL Ampule 75.98 - 124.98 75.98 720. Sodium Bicarbonate 1 mEq/mL, 100 mL Vial 85.00 - 280.00 85.00 721. Sodium Bicarbonate 1 meq/mL, 50 mL Ampule 84.21 - 123.85 101.94 722. Sodium Bicarbonate 1 meq/mL, 50 mL Vial 85.00 - 154.78 99.00

2019 DPRI |Seventh Edition 34 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 723. Sodium Bicarbonate 650 mg Tablet 0.68 - 1.40 0.68 724. So dium Chloride 2.5 mEq/mL, 20 mL Vial 21.60 - 56.25 38.00 725. Sodium Chloride 2.5 mEq/mL, 50 mL Vial 45.00 - 58.00 45.00 726. Somatostatin 250 mcg Ampule 638.00 - 858.88 638.00 727. Somatostatin 250 mcg Vial 718.20 - 798.00 718.20 728. Somatostatin 3 mg Ampule 4,263.00 - 4,263.00 4,796.10 729. Somatostatin 3 mg Vial 4,391.10 - 4,391.10 5,638.68 730. Spironolactone 25 mg Tablet 6.79 - 22.75 9.90 731. Spironolactone 50 mg Tablet 27.40 - 33.08 31.11 732. Standard Senna Concentrate 187 mg Tablet 7.55 - 8.00 7.55 733. Sterile Water For injection 1 L Bottle 50.00 - 103.00 50.00 734. Sterile Water For injection 100 mL Bottle 25.34 - 49.50 25.34 735. Sterile Water For injection 20 mL Ampule 26.00 - 30.00 26.00 736. Sterile Water For injection 50 mL Bottle 16.98 - 210.00 21.22 737. Streptokin ase 1,500,000 IU Vial 3,800.00 - 4,000.00 6,160.00 738. Streptomycin 1 g Vial 10.00 - 26.00 14.61 739. Sucralfate 1 g Tablet 20.00 - 45.15 30.72 740. Sugammadex 100 mg/mL, 2 mL Vial 4,731.35 - 4,731.35 5,270.07 741. Suxamethonium (Succinylcholine) 20 mg/mL, 10 117.43 - 298.00 144.33 mL Vial T 742. Tacrolimus 1 mg slow-release capsules - 93.16 743. Tafluprost 15 mcg/mL, 0.3 mL single dose - 991.00● ophthalmic solution Bottle 744. Tamoxifen 20 mg Tablet 5.00 - 13.12 7.25 745. Tamsulosin 200 mcg Capsule 14.68 - 49.23 19.00

2019 DPRI |Seventh Edition 35 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 746. Tamsulosin 200 mcg Orally Disintegrating Tablet 10.77 - 51.57 45.41 747. Tamsulosin 400 mcg MR Film Coated Tablet 11.51 - 73.04 22.50 748. Telmisartan + Hydrochlorothiazide 40 mg + 12.5 17.20 - 21.21 19.02 mg Tablet 749. Telmisartan 40 mg Tablet 4.30 - 18.88 13.75 750. Telmisartan 80 mg Tablet 5.56 - 34.02 26.00 751. Terazosin 1 mg Tablet 51.84 - 58.76 51.84 752. Terazosin 2 mg Tablet 25.00 - 83.66 25.00 753. Terbutaline 500 mcg/mL, 1 mL Ampule 44.48 - 98.00 44.48 754. Thiamazole (Methimazole) 5 mg Tablet 5.06 - 25.00 5.40 755. Thiopental Sodium 1 g + 50 mL diluent Vial 978.38 - 1,198.48 978.38 756. Timolol Eye Drops 0.5%, 5 mL Bottle 193.00 - 375.00 327.50 757. Tinzaparin Sodium 10,000 anti-XA IU/mL, 0.35 387.73 - 432.62 387.73 mL Pre-filled syringe 758. Tin zaparin (as sodium) 10,000 anti-XA IU/mL, - 266.91 0.45 mL pre-filled syringe 759. Tinzaparin Sodium 10,000 anti-XA IU/mL, 2 mL - 796.96 Vial 760. Tiotropium (as bromide) 18 mg mcg/dose with - 64.21 appropriate accompanying dispenser 761. Tobramycin + Dexamethasone Eye Drops 0.3% 85.00 - 350.00 201.00 + 0.1%, 5 mL Bottle 762. Tobramycin + Dexamethasone Eye Ointment 350.00 - 491.96 469.08 0.3% + 0.1%, 3.5 g Tube 763. Tobramycin Eye Drops 0.3%, 5 mL Bottle 100.00 - 350.00 197.50 764. Tobramycin Eye Ointment 0.3%, 3.5 g Tube 453.33 - 500.00 453.33 765. Topiramate 25 mg Tablet 12.45 - 15.45 12.45 766. Topiramate 50 mg Tablet 9.00 - 10.00 9.90 767. Tramadol 100 mg MR Tablet 4.72 - 90.80 72.64 768. Tramadol 50 mg Dispersible Tablet 1.92 - 40.13 1.92 769. Tramadol 50 mg Capsule 0.91 - 7.50 2.50

2019 DPRI |Seventh Edition 36 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 770. Tramadol 50 mg/ml, 1 ml Ampule 7.62 - 58.00 9.62 771. Tramadol 50 mg/ml, 2 ml Ampule 3.69 - 84.62 6.73 772. Tranexamic Acid 100 mg/mL, 5 mL Ampule 8.05 - 1,460.00 15.78 773. Tranexamic Acid 500 mg Capsule 3.54 - 21.44 5.76 774. Tranexamic Acid 500 mg Tablet 4.50 - 11.48 5.69 775. Trastuzumab 120 mg/mL, 5 mL Vial - 26,000.00● 776. Trastuzumab 150 mg Lyophilized Powder - 29,148.27 777. Trimetazidine 35 mg Tablet 1.02 - 14.86 4.07 778. Tropicamide + Phenylephrine Hydrochloride 5 - 665.00● mg/5 mg, 10 mL Bottle 779. Tropicamide Eye Drops 0.5%, 5 mL Bottle 380.97 - 414.83 380.97 U 780. Urso deoxycholic Acid 250 mg Capsule 26.00 - 46.00 36.04 781. Ursodeoxychloic Acid 500 mg Tablet - 95.00● V 782. Vaccine, Hepatitis B (recombinant DNA) 10 123.22 - 1,647.00 133.72 mcg/0.5 mL (pediatric) Monodose Vial 783. Vaccine, Hepatitis B (recombinant DNA) 20 158.34 - 632.00 181.05 mcg/mL, 1 mL Vial 784. Vaccine, Rabies Chick Embryo Cell (Purified 800.00 - 1,750.00 1,209.00 Inactivated) 2.5 IU/mL, 1 dose + 1 mL diluent Vial 785. Vaccine, Tetanus Toxoid 0.5 mL Ampule 24.22 - 108.00 36.42 786. Vaccine, Vero Cell (purified) 2.5 IU/0.5 mL Vial 587.44 - 1,300.00 906.00 + diluent 787. Valaciclovir 500 mg Tablet 31.61 - 100.94 31.61 788. Valproic Acid + Sodium Valproate 500 mg MR 7.45 - 23.00 14.45 Tablet 789. Valproic Acid 250 mg/5 mL, 120 mL Syrup 314.05 - 561.39 314.05 790. Valproic Acid 500 mg/5 mL, 5 mL Vial 1,701.20 - 1,701.20 2,500.00

● The Reference Price was based on the proposed list price of the pharmaceutical company upon its inclusion in the Philippine National Formulary (excluded from the maximum 10% inflationary cost) The Reference Price was based on the Maximum Wholesale Price (MWP) plus Value-Added-Tax (VAT) (excluded from the maximum 10% inflationary cost) Health facilities may have a price variation up to 10% above the DPRI to account for inflation 2019 DPRI |Seventh Edition 37 | P a g e Lowest - 2019 Drugname Highest DPRI (GIDA Area) 791. Valsartan + Hydrochlorothiazide 80 mg + 12.5 9.23 - 28.89 12.05 mg Tablet 792. Valsartan 160 mg Tablet 9.23 - 60.50 11.38 793. Valsartan 80 mg Tablet 7.23 - 41.31 8.45 794. Vancomycin 1 g Vial 250.00 - 550.00 344.30 795. Vancomycin 500 mg Vial 95.00 - 850.00 158.23 796. Verapami l 2.5mg/ml, 2mL Ampule 126.48 - 780.00 126.48 797. Verapamil 80 mg Tablet 25.20 - 44.37 32.63 798. Vinblastine 1 mg/mL, 10 mL Vial 800.00 - 1,200.00 890.32 799. Vinblastine 10 mg Vial 800.00 - 890.32 800.00 800. Vincristine (As Sulfate) 1 mg/mL, 1 mL Vial 201.00 - 600.00 267.00 801. Vincristine (As Sulfate) 1 mg/mL, 2 mL Vial 318.00 - 695.00 400.00 802. Vitamin B1 B6 B12 100 mg + 100 mg + 1 mg, 3 13.33 - 190.00 34.98 mL Ampule 803. Vitamin B1 B6 B12 100 mg + 5 mg + 50 mcg 3.73 - 3.85 3.73 Capsule 804. Vitamin B1 B6 B12 100 mg + 5 mg + 50 mcg 0.75 - 2.80 1.50 Tablet 805. Voriconazole 200 mg Film coated tablet 1,000.00 - 1,000.00 1,467.00 806. Voriconazole 200 mg lyophilized powder for 5,600.00 - 5,600.00 solution, 30 mL Vial 5,900.00 W 807. Warfarin 1 mg Tablet 17.63 - 20.94 17.63 808. Warfarin 2.5 mg Tablet 7.85 - 22.42 10.00 809. Warfarin 5 mg Tablet 9.40 - 30.52 12.29 Z 810. Zinc 27.5 mg/mL (Equiv. to 10 mg Elemental 24.00 - 76.00 38.00 Zinc), 15 mL Oral Drops 811. Zinc 55 mg/5 mL (Equiv. to 20 mg Elemental 31.50 - 109.00 41.00 Zinc), 60 mL Syrup 812. Zolpidem 10 mg Tablet 34.50 - 64.00 60.00

Health facilities may have a price variation up to 10% above the DPRI to account for inflation

2019 DPRI |Seventh Edition 38 | P a g e