When Used in Risk of Withdrawal Substance Possible Effects Combination with Dependency? Symptoms Alcohol
Symptoms of an Alcohol Overdose: irritability; euphoria; Breathing is slow, sweating; tremors; drowsiness; shallow or has nausea; anxiety; respiratory stopped; skin is cold, difficulty Alcohol yes depression; clammy, or blue; sleeping; in severe constricted pupils; vomiting while circumstances: nausea passed out; loss of seizures and/or consciousness/unres hallucinations ponsive
enhanced sensory perception and euphoria followed by drowsiness/relaxa Increased heart tion; slowed rate; blood reaction time; irritability; trouble Cannabis pressure; further yes problems with sleeping; decreased (marijuana) slowing of mental balance and appetite; anxiety processing and coordination; reaction time increased heart rate and appetite; problems with learning and memory; anxiety euphoria; increased energy and alertness; anxiety; restlessness; severe cravings; increased risk of erratic behavior; depression; cardiac toxicity heart rhythm tiredness; increased (damage to the problems; seizure; appetite; insomnia; heart by harmful Cocaine yes increased body vivid unpleasant chemicals) than temperature, dreams; slowed from use of cocaine heart rate and thinking and or alcohol on its blood pressure; movement; own headache; restlessness abdominal pain and nausea; panic attacks; stroke coma
cough relief; euphoria; slurred DXM speech; increased (dextromethorpha yes heart rate and unknown unknown n) ‐ (Robitussin®, blood pressure; NyQuil®) dizziness; nausea; vomiting euphoria; drowsiness; nausea; vomiting; confusion; insomnia; anxiety; memory loss; loss nausea; problems Gamma‐ tremors; sweating; of consciousness; with breathing, hydroxybutyrate yes increased heart rate slowed heart rate greatly increased (GHB) and blood pressure; and breathing; depressant effects psychotic thoughts lower body temperature; seizures; coma; death
Hallucinogens:
numbness; disorientation and confusion; dizziness, nausea, and vomiting; changes in sensory perception; hallucinations; Ayahuasca, DMT, unknown feelings of unknown unknown Khat, Salvia detachment from self and environment; increase in blood pressure, heart rate, respiration, and body temperature
increased risk of Ketamine yes unknown adverse effects LSD, Mescaline (Peyote), no unknown unknown Phencyclidine (PCP)
euphoria; dry severe cravings; mouth; itching; restlessness; muscle dangerous slowing nausea; vomiting; and bone pain; of heart rate and Heroin yes inability to feel insomnia; diarrhea; breathing; coma; pain (analgesia); vomiting; cold death slowed breathing flashes with goose and heart rate bumps
confusion; nausea; slurred speech; lack of coordination; euphoria; dizziness; drowsiness; disinhibition; nausea; tremors; lightheadedness; irritability; Inhalants yes unknown hallucinations; problems sleeping; headaches; mood changes sudden sniffing death due to heart failure; death from asphyxiation or suffocation; brain damage from lack of oxygen nausea; dizziness; itching; sweating; muscle aches; dry mouth; insomnia; constipation; irritability; hostility; increased Kratom yes unknown aggression; urination; loss of emotional changes; appetite; runny nose; jerky hallucinations movements with long term‐ high dose usage
lowered inhibition; MDMA decreases enhanced sensory some of alcohol's perception; effects; alcohol can increased heart increase plasma rate and blood fatigue; loss of concentrations of MDMA pressure; muscle appetite; unknown MDMA, which may (Ecstasy/Molly) tension; nausea; depression; trouble increase the risk for faintness; chills or concentrating neurotoxic effects sweating; sharp (damage to the rise in body brain and nervous temperature could system) lead to kidney failure or death increased wakefulness and physical activity; decreased appetite; Masks the increased depressant effect of breathing, heart alcohol, increasing Methamphetamin rate, blood depression; anxiety; yes the risk of alcohol e pressure, and tiredness overdose; may temperature; increase blood irregular pressure heartbeat; insomnia; confusion; anxiety; erratic behavior; hallucinations
Prescription Central Nervous System Depressants:
drowsiness; seizures; shakiness; slurred speech; anxiety; agitation; poor insomnia; concentration; overactive reflexes; Barbiturates: Further slows heart confusion; increased heart Pentobarbital rate and breathing, yes dizziness; rate, blood (Nembutal®), which can lead to problems with pressure, and Phenobarbital death movement and temperature with memory; lowered sweating; blood pressure; hallucinations; slowed breathing severe cravings
Benzodiazepines: Xanax®, Librium®, yes Valium®
Sleep Medications: yes Lunesta®, Sonata®, Ambien® Prescription Opioids: codeine, fentanyl, Vicodin® restlessness; muscle (hydrocodone), pain relief; and bone pain; Dilaudid®, drowsiness; dangerous slowing insomnia; diarrhea; Demerol®, nausea; of heart rate and yes vomiting; cold methadone, constipation; breathing, leading to flashes with morphine, euphoria; slowed coma or death goosebumps; leg OxyContin® and breathing; death movements Percocet® (Oxycodone), Opana®
Prescription Stimulants:
Increased alertness, attention, energy; masks the increased blood depressant effect of pressure and heart alcohol, increasing depression; Adderall® yes rate; narrowed the risk of alcohol tiredness; sleep (Amphetamine) blood vessels; overdose; may problems increased blood increase blood sugar; opened‐up pressure breathing passages.
Ritalin®, Concerta® yes (Methylphenidate ) hallucinations; altered perception of time; inability to distinguish fantasy from reality; panic; may decrease the Psilocybin (Magic unknown muscle relaxation perceived effects of Unknown mushrooms) or weakness; alcohol problems with movement; enlarged pupils; nausea; vomiting; drowsiness
Drowsiness, sedation, sleep; amnesia, blackout; decreased anxiety; Headache; muscle muscle relaxation, pain; extreme impaired reaction anxiety, tension, time and motor severe sedation, restlessness, coordination; unconsciousness, confusion, Rohypnol® impaired mental slowed heart rate irritability; yes (Flunitrazepam) functioning and and breathing, numbness and judgment; which can lead to tingling of hands or confusion; death feet; hallucinations, aggression; delirium, excitability; convulsions, slurred speech; seizures, or shock. headache; slowed breathing and heart rate. improved athletic performance; acne; fluid Mood swings; retention; oily tiredness; skin; kidney and restlessness; loss of liver damage; high increased risk of appetite; insomnia; Steroids (Anabolic) yes blood pressure; violent behavior lowered sex drive; increased risk of depression, stroke or heart sometimes leading attack; increased to suicide attempts. aggression and extreme mood swings
increased heart rate; vomiting; agitation; Synthetic Headaches, anxiety, confusion; Cannabinoids (ex. yes unknown depression, hallucinations, K2, Spice) irritability. anxiety, paranoia; increased blood pressure. Increased heart rate and blood pressure; euphoria; increased sociability and sex drive; paranoia, agitation, and Synthetic hallucinations; Depression; anxiety; Cathinones (bath yes violent behavior; unknown tremors; problems salts) sweating; nausea, sleeping; paranoia vomiting; insomnia; irritability; dizziness; depression; panic attacks; reduced motor control; cloudy thinking.
increased blood pressure, breathing, and heart rate; increased risk of Tobacco and cancer and heart irritability; attention Nicotine disease; and sleep problems; (cigarettes, yes unknown emphysema depression; eCigarettes/Juul, (Whether use of increased appetite chewing tobacco) eCigarettes/Juuls leads to an increased risk of cancer is currently unknown.) [1] National Institute on Drug Abuse, "Commonly Abused Drugs Charts," National Institutes of Health, last modified July 2, 2018, https://www.drugabuse.gov/drugs‐abuse/commonly‐abused‐ drugs‐charts.