Authors: Pallavi Subhraveti Ron Caspi Quang Ong Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_001561915Cyc: Tepidibacillus sp. Z9 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari 2-dehydro- 3-deoxy-D- uracil gluconate

a 2,3,4-saturated fatty acid cis-vaccenate

RS06855 RS08995 RS07195 RS08655 RS04025 RS09975 RS03445 RS11130 RS03250 RS02125 RS00195 RS10905 RS07710 RS01390 RS04165 RS14070 RS04160 RS10505 RS02720 RS02150 RS05775 RS12980 RS07690 RS07815 RS06965 RS00930 RS14100 RS03270 RS01185 RS12295 RS03095 RS06585 RS11465 RS11900 RS11140 RS12625 RS06050 RS08850 RS01265 RS11790 RS09895 RS13055 RS03395 RS02660 RS00885 RS06650 RS10380 RS13165 RS12785 RS00160 RS11555 RS07270 RS12075 RS10725 RS08740 RS02470 RS11345 RS02825 RS12330 RS10265 RS09125 RS02860 RS09070 RS03845 RS13670 RS09270 RS02515 RS13885 RS08555 RS02210 RS00935 RS08255 RS13445 RS08110 RS08085 RS05615 RS04770 RS12055 RS00725 RS05190 RS12960 RS01955 RS12540 RS11760 RS02195 RS12510 RS08285 RS09455 RS00970 RS08225 RS01700 RS09065 RS12360 RS00635 RS13705 RS01395 RS08570 RS09630 RS12575 RS12205 RS03605 foldase

RS04050 RS13215 uracil 2-dehydro- a 2,3,4-saturated fatty acyl CoA 3-deoxy-D- cis-vaccenoyl-CoA gluconate RS10590 RS02130

RS14260 RS10825 Macromolecule Modification RS00735 Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Chlorinated Compound Degradation lipoprotein posttranslational Nucleoside and Nucleotide Degradation a 2-oxo DNA combined a cytidine 1402 (S)-4-amino-5- (2R,3S)-3- a (3R)-3- RS02280 [2Fe-2S] iron-sulfur cluster biosynthesis a purine ethylnitronate a purine with exogenous cobalt-precorrin-7 hydroxypimeloyl- (R)-NADPHX (S)-NADHX chorismate RS10850 superpathway of menaquinol-7 biosynthesis demethylmenaquinol- thiamine salvage II S-adenosyl-L-methionine cycle I demethylmenaquinol- modification 4,5-dichlorocatechol carboxylate arsenate GTP in 16S rRNA oxopentanoate isopropylmalate superpathway of thiamine diphosphate biosynthesis I 2-oxoacid:ferredoxin ribonucleoside adenosylcobinamide 2-nitropropane ribonucleoside DNA to form a 16S rRNA bifunctional cobalt- glutamate-1- 3-isopropylmalate [acp] methyl ester bifunctional bifunctional chorismate 6 biosynthesis I 9 biosynthesis degradation 3-hydroxyacyl- a [prolipoprotein]- superpathway of purine deoxyribonucleosides degradation oxidoreductase 5'-triphosphate bifunctional dioxygenase: purine-nucleoside recombinational bifunctional (cytosine(1402)-N(4) precorrin-7 (C(5))- semialdehyde dehydratase ADP-dependent ADP-dependent mutase: RS12505 L-cysteine desulfurase all-trans- 4-amino-2-methyl-5- all-trans- inosine 5'-phosphate crossover junction [acyl-carrier- chorismate 2-carboxy-1,4- SAM 2-carboxy-1,4- L-cysteine superpathway of pyrimidine 4,5-dichlorobenzene- subunit gamma: adenosylcobinamide U473_RS07000 phosphorylase: junction 3,4-dihydroxy- )-methyltransferase: methyltransferase/ 2,1-aminomutase: large subunit: NAD(P)H-hydrate NAD(P)H-hydrate U473_08285 cys hexaprenyl pyrimidinemethanol nonaprenyl degradation endodeoxyribonuclease protein] RS11275 naphthoquinol naphthoquinol prolipoprotein deoxyribonucleosides degradation 1,2-diol U473_RS04210 kinase/ U473_RS04365 2-butanone- U473_RS05080 cobalt-precorrin- U473_RS00920 U473_RS08370 dehydratase/ dehydratase/ cysteine diphosphate diphosphate 2-nitropropane RuvC: U473_RS02810 dehydratase bifunctional isochorismate 1,4-dihydroxy- bifunctional 1,4-dihydroxy- diacylglyceryl 2'-deoxyguanosine adenosylcobinamide- purine-nucleoside 4-phosphate 6B (C(15))- NAD(P)H-hydrate NAD(P)H-hydrate desulfurase: synthase: cysteine 2-naphthoate hydroxymethylpyrimidine methionine 2-naphthoate 2'-deoxycytidine a reduced [+ 2 isozymes] dioxygenase: Holliday junction 16S rRNA glutamate-1- 3-isopropylmalate FabZ: chorismate desulfurase: transferase: IMP 2,3-dichloro- phosphate U473_RS07100 phosphorylase: synthase/GTP (cytosine(1402)-N(4) methyltransferase: semialdehyde- dehydratase epimerase: epimerase: mutase/ U473_RS09535 U473_RS08930 polyprenyltransferase: kinase/ adenosyltransferase: polyprenyltransferase: 2'-deoxyadenosine H + ferredoxin [iron- CO an acyl-CoA [unspecified resolution ofresolvase RuvX: a (2E)- U473_RS11665 RS03170 U473_RS10510 IMP 2 guanylyltransferase: U473_RS04370 cyclohydrolase II: U473_RS10085 U473_RS13715 U473_RS13715 cysteine U473_RS09535 U473_RS09820 phosphomethylpyrimidine U473_RS11000 U473_RS09820 cytidine cis,cis-muconate sulfur] cluster degradation nitrite acetaldehyde U473_RS03115 )-methyltransferase: 2,1-aminomutase: small subunit: enoylpimeloyl- prephenate RS12775 dehydrogenase: U473_RS10040 ribose-1-arsenate a purine base recombinational 2,5-diamino-6-U473_RS10155 isochorismate [+ 2 isozymes] demethylmenaquinol-6 demethylmenaquinol-9 prolipoprotein purine-nucleoside deaminase: a purine adenosyl- 4 U473_RS06865 cobalt-precorrin-8 U473_RS02545 U473_RS08365 (S)-NADPHX NADH dehydratase: desulfurase: kinase: U473_RS06255 U473_RS12685 products] junction (5-phospho-D- an N - (2S)-2- [acp] methyl ester an [L-cysteine diacylglyceryl U473_RS03460 ribonucleoside cobinamide 1402 U473_RS12090 U473_RS12580 met SAH phosphorylase: thymidine XMP formation of two formate ribosylamino) methylcytidine 5-aminolevulinate 2-succinyl-6- desulfurase]-S- isopropylmalate + + HMP-P transferase: U473_RS04370 5'-diphosphate phosphate in 16S rRNA prephenate H RS11835 H an S-sulfanyl-[L- hydroxy-2, 4- sulfanyl-L-cysteine 5'-methylthioadenosine/ 2-chloro-2-(2-chloro- intact strands pyrimidin- methionine U473_RS01950 purine-nucleoside 2'-deoxyuridine cysteine desulfurase] cyclohexadiene- cysteine 5-(2-hydroxyethyl) bifunctional S-adenosylhomocysteine demethylmenaquinol- bifunctional 5-oxofuran-2-yl)acetate 4(3H)-one RS08845 synthase: a [prolipoprotein]- phosphorylase: 1-carboxylate a ThiS sulfur- desulfurase: -4-methylthiazole hydroxymethylpyrimidine nucleosidase: 8 biosynthesis I (S-diacylglyceryl) 2'-deoxyinosine purine-nucleoside uridine thymine metallophosphatase/ U473_RS09385 U473_RS01980 phosphorylase: U473_RS04365 5'-nucleotidase: RS03045 synthase: carrier protein U473_RS09535 kinase/ -L-cysteine phosphorylase: a nascent peptidoglycan a peptidoglycan all trans-decaprenyl- 2-methoxy-6-all 2251 a (3R)-3- a (3R)-3- a (3R,5Z)-3- hydroxyethylthiazole 2-carboxy-1,4- U473_RS04370 adenosyl- guanosine acetyl-CoA U473_RS08920 cysteine phosphomethylpyrimidine S-ribosyl-L- U473_RS11200 U473_RS02020 with (L-alanyl-γ-D- with (L-alanyl-γ-D- 2-methoxy-6- trans-nonaprenyl- cob(I)yrinate hydroxyhexacosanoyl- hydroxydocosanoyl- hydroxydodec- (S)-NADPHX met an S-sulfanyl-[cysteine kinase: U473_RS06250 L-homocysteine naphthoquinol 5-chloro-trans a tRNA precursor CTP ATP ATP cobinamide GTP GTP H O in 23S rRNA RS07950 desulfurase: kinase: U473_RS06255 homocysteine 1,4-dihydroxy- signal peptidase purine-nucleoside purine-nucleoside glutamyl-meso-2,6- glutamyl-meso-2,6- 1,4-benzoquinol 1,4-benzoquinol a,c-diamide 2 23S rRNA [acp] [acp] 5-enoyl-[acp] bifunctional acetyl-CoA desulfurase]-[disordered- 2-succinyl-5- 4-methyl-5-(2- -dienelactone bifunctional bifunctional phosphate 3-hydroxyacyl- 3-hydroxyacyl- 3-hydroxyacyl- bifunctional U473_RS12580 2-naphthoate II: U473_RS06665 phosphorylase: phosphorylase: uracil 2-deoxy-α- xanthosine diaminopimeloyl-D- diaminopimeloyl-D- CCA tRNA cob(I)yrinic acid bifunctional ribosome (guanosine(2251) ADP-dependent carboxylase form scaffold enolpyruvyl- D-glyceraldehyde phosphooxyethyl) HMP-PP dienelactone L,D- demethylmenaquinone demethylmenaquinone [acyl-carrier- [acyl-carrier- [acyl-carrier- ornithine a carboxy- a [ThiI sulfur- polyprenyltransferase: U473_RS04370 U473_RS04365 D-ribose 1- alanine) tetrapeptide alanine) tetrapeptide nucleotidyltransferase: a,c-diamide adenosylcobinamide small subunit- -2'-O)- NAD(P)H-hydrate carboxyl protein] complex 6-hydroxy-3- 3-phosphate thiazole an (S-diacyl- hydrolase: transpeptidase: methyltransferase/2- methyltransferase/2- protein] protein] protein] acetyltransferase/ RS05955 adenylated-[ThiS carrier protein]-S- U473_RS09820 a lipoprotein purine-nucleoside phosphate purine-nucleoside a nascent peptidoglycan U473_RS05935 adenosyltransferase: kinase/ dependent methyltransferase dehydratase/ transferase cysteine cyclohexene- 1-deoxy-D- tyr S-ribosylhomocysteine demethylmenaquinol-8 sn-glyceryl) U473_RS05500 U473_RS05695 methoxy-6-polyprenyl-1,4- methoxy-6-polyprenyl-1,4- dehydratase dehydratase dehydratase N-acetylglutamate RS10490 AIR sulfur-carrier protein] sulfanyl-L-cysteine NAD biosynthesis signal peptide phosphorylase: phosphopentomutase: phosphorylase: with L,D cross links tRNA CCA- U473_RS10060 adenosylcobinamide- GTPase A: RlmB: NAD(P)H-hydrate subunit beta: desulfurase: 1-carboxylic- xylulose-5- thiamine lyase: U473_RS01975 -L-cysteinyl- D-ala benzoquinol methylase: benzoquinol methylase: FabZ: FabZ: FabZ: synthase: I (from aspartate) guanylyl molybdenum U473_RS04365 U473_RS04360 U473_RS04365 (meso-diaminopimelate pyrophosphorylase: ATP:cob(I)alamin phosphate U473_RS06495 U473_RS13200 epimerase: U473_RS01295 U473_RS09535 acid synthase: phosphomethylpyrimidine phosphate 2-iminoacetate phosphate [apolipoprotein] 5-chloromaleylacetate 6-methoxy-3-methyl-U473_RS06040 6-methoxy-3-methyl-2-U473_RS06040 2-O- U473_RS11665 U473_RS11665 U473_RS11665 U473_RS10640 cofactor biosynthesis containing) a tRNA U473_RS08620 adenosyltransferase: guanylyltransferase: [+ 3 isozymes] U473_RS13715 cysteine U473_RS08925 synthase ThiC: synthase: synthase ThiH: synthase: 2-deoxy-D-ribose purine-nucleoside 2-all-trans-decaprenyl- all-trans-nonaprenyl- methylguanosine 2251 a (2E)-hexacos- a (2E)-docos- a (2E,5Z)-dodeca- N-acetyl-L- [+ 3 isozymes] U473_RS05315 MoO - 5-phosphate containing a adenosyl-U473_RS00955 U473_RS10040 phosphate GDP H + 2-enoyl-[acp] 2-enoyl-[acp] 3,5-dienoyl-[acp] methionine RS10940 desulfurase: 2-succinyl-5- U473_RS00095 U473_RS04115 U473_RS05320 asp 2 2-deoxy-α-D-ribose 1-phosphate phosphorylase: 1,4-benzoquinol 1,4-benzoquinol adenosylcobinamide- in 23S rRNA NADPH malonyl-CoA RS04685 molybdopterin 3' CCA end PPP cobyrinate U473_RS12580 enolpyruvoyl- a thiocarboxy- thiamine L-aspartate thiamine salvage III a peptide U473_RS04370 i 1-deoxy-D-xylulose 4-aminobenzoate cofactor an N-acyl-(S- GDP a [cysteine desulfurase]- 6-hydroxy-3- HMP-P [ThiS-Protein] 2-iminoacetate phosphate oxidase: molybdopterin- phosphopentomutase: deoxyribose- (2Z,4Z)-2-chloro- a,c-diamide 5-phosphate biosynthesis diacyl-sn-glyceryl) xanthine S-sulfanyl-[disordered- cyclohexene- synthase: U473_RS02330 guanine U473_RS04360 phosphate 3-hydroxyhexa- form scaffold bifunctional thiamine -L-cysteinyl- 1-carboxylate U473_RS06245 2-iminosuccinate dinucleotide thiamine Fatty Acid and Lipid Biosynthesis aldolase: 2,4-dienedioate a 2-methoxy-6-all- 2-methoxy-6-all 4-(cytidine 5'- a (3R)-3- a (3R,7Z)-3- a (3R)-3- a (3R,5Z)-3- RS03950 protein] complex hydroxymethylpyrimidine thiazole chorismate [lipoprotein] a 2,3,4-saturated a 2,3,4-saturated 2- D-ribulose an unsulfurated RS09870 2-succinyl-6- biosynthesis diphosphokinase: 2-deoxy-D-ribose 5-phosphate U473_RS03375 trans-polyprenyl- trans-hexaprenyl- a purine cys diphospho)-2-C- hydroxytetracosanoyl- hydroxytetradec- hydroxyglutaryl- hydroxy-tetradec- prephenate ser cysteine kinase/ synthase: anthranilate/ IMP fatty acyl-[acp] lysophosphatidate 5-phosphate [sulfur carrier] hydroxy-2, 4- protein B: U473_RS06465 1,4-benzoquinol 1,4-benzoquinol ribonucleoside bifunctional methyl-D-erythritol [acp] 7-enoyl-[acp] [acp] methyl ester 5-enoyl-[acp] bifunctional desulfurase: phosphomethylpyrimidine U473_RS05325 L-cysteine biosynthesis thiamine aminodeoxychorismate guanylyl palmitate biosynthesis II (bacteria and plants) 1-acyl-sn-glycerol- bifunctional bifunctional cysteine 4-(cytidine 5'- 3-hydroxyacyl- 3-hydroxyacyl- 3-hydroxyacyl- 3-hydroxyacyl- L-serine cyclohexadiene- U473_RS13845 thiamine stearate biosynthesis gondoate biosynthesis deoxyribose-phosphate D-glyceraldehyde bifunctional purine-nucleoside 3,4-dihydroxy- chorismate U473_RS09535 kinase: U473_RS06255 VI (from L-methionine) phosphate synthase component molybdenum acetaldehyde urate (2Z)-5-chloro-4- 3-phosphate demethylmenaquinone demethylmenaquinone desulfurase: diphospho)- [acyl-carrier- [acyl-carrier- [acyl-carrier- [acyl-carrier- ammonia-lyase, 1-carboxylate 2-[(2R,5Z)-2-carboxy- diphosphate II (bacteria and plants) (anaerobic) aldolase: U473_RS03375 3-phosphate phosphoribosylaminoimidazolecarboxamide phosphorylase: 2-butanone- mutase/ cysteine quinolinate II: U473_RS08115 cofactor tRNA processing hydroxyhex-2-enedioate acyltransferase: methyltransferase/2- methyltransferase/2- U473_RS12580 2-C-methyl-D- protein] protein] protein] protein] iron-sulfur- RS04960 synthase: 4-methylthiazol-5(2H)- an acetoacetyl-[acp] formyltransferase/IMP U473_RS04365 4-phosphate prephenate RS09600 desulfurase: HMP-PP [+ 2 isozymes] U473_RS06125a 2,3,4-saturated methoxy-6-polyprenyl-1,4- methoxy-6-polyprenyl-1,4- cysteine erythritol kinase: dehydratase dehydratase dehydratase dehydratase dependent, U473_RS08920 ylidene]ethyl phosphate met 4-amino-4- cyclohydrolase: U473_RS00065 purine-nucleoside synthase/GTP dehydratase: U473_RS12580 (1R,6R)-6-hydroxy- a palmitoyl-[acp] a malonyl-[acp] an oleoyl-[acp] acetaldehyde D-glyceraldehyde 3-phosphate 1,2-diacyl-sn benzoquinol methylase: benzoquinol methylase: desulfurase: 2-phospho-4-(cytidineU473_RS12900 FabZ: FabZ: FabZ: FabZ: subunit beta: an S-sulfanyl-[cysteine methionine deoxychorismate 3-oxoacyl-ACP 3-oxo-stearoyl- a polycistronic FAICAR acyl-carrier protein phosphorylase: cyclohydrolase II: U473_RS12090 2-succinylcyclohexa- thiamine (11Z)-3-oxo- -glycerol 3- a 6-methoxy-3-methyl-U473_RS06040 6-methoxy-3-methyl-2-U473_RS06040 U473_RS09535 5'-diphospho)-2-C- U473_RS11665 U473_RS11665 U473_RS11665 U473_RS11665 U473_RS06435 thiamine adenosyltransferase: reductase: tRNA precursor guanosine nucleotides U473_RS04370 3 7 a (2E)- a (2E,5Z)- keto- desulfurase]-S- 2,4-diene-1- diphosphate [acp] synthase: icos-11-enoyl- acetyl-CoA α U473_RS10155 a sulfurated a (2E)-tetracos- a trans-∆ -cis-∆ - RS01865 phosphate U473_RS11000 U473_RS02000 degradation III 2-maleylacetate phosphate 2-all-trans-polyprenyl- all-trans-hexaprenyl- -D-ribose- 1-deoxy-L- ala methyl-D-erythritol enoylglutaryl- tetradeca-2,5- phenylpyruvate pyruvate sulfanyl-[disordered- carboxylate NaMN U473_RS06350 [acp] synthase: a purine base [sulfur carrier] 2-enoyl-[acp] tetradecenoyl-[acp] synthase: SAM menaquinol-8 biosynthesis [+ 3 isozymes] a 3-oxooctadecanoyl- 1,4-benzoquinol 1,4-benzoquinol 1-phosphate glycero-tetrulose formate [acp] methyl ester dienoyl-[acp] RS13735 form scaffold o-succinylbenzoate an (11Z)-3-U473_RS06350 U473_RS05315 nicotinic acid a (3R)-3- [acp] 4-phosphate protein] complex synthase: molybdenum cofactor biosynthesis 4-aminobenzoate oxo-icos-11- acetyl-CoA purine ribonucleosides degradation cysteine mononucleotide demethylmenaquinol-8 hydroxybutanoyl- 3-oxoacyl-ACP GMP desulfurase: U473_RS09460 thiamine enoyl-[acp] a tRNA precursor bifunctional [acp] 6 RS02285 phosphate adenylyltransferase: bifunctional reductase: 3-oxoacyl-[acyl- with a 5' exoribonuclease: an N -L- di-trans,octa-cis 2-methoxy-6-all a 3,5,7,9,11,13,15- 527 (R)-2- a (3R)-3- a (3R,6Z)-3- a (5Z)-3- U473_RS09535 metallophosphatase/ 3-oxoadipate a sulfurated adenosylcobinamide- α-ribazole UDP-N-acetyl- 5'-deoxy-5'- a guanine 2-succinylbenzoate synthase: 6-hydroxymethyl-dihydropterin U473_RS03215 demethylmenaquinone 3-hydroxyacyl- U473_RS02000 carrier-protein] extension and U473_RS10190 a tRNA precursor threonylcarbamoyladenine 37 -undecaprenyl trans-octaprenyl- a purine 2'- hepta-oxo- hydroxyglutaryl- phe hydroxyicosanoyl- hydroxyoctadec- oxododec- RS01850 cysteine ATP adenosine 5'-nucleotidase: [sulfur carrier] GDP 5'-phosphate α-D-glucosamine fluoroadenosine in 16S rRNA dIDP U473_RS06245 SAH diphosphate biosynthesis I nicotinate adenine methyltransferase/2- [acyl-carrier- [+ 3 isozymes] reductase: a long 3' trailer with a 5' in tRNA adenosylcobinamide- phosphate 1,4-benzoquinol deoxyribonucleoside purine-nucleoside hexadecanoyl-[PKS-acp] 16S rRNA CoA [acp] 6-enoyl-[acp] 5-enoyl-[acp] desulfurase: o-succinylbenzoate- cys U473_RS02020 tRNA (N(6)-L- undecaprenyl- bifunctional aldo/keto 2-hydroxyglutaryl- aspartate 3-hydroxyacyl- 3-hydroxyacyl- 3-oxoacyl-[acyl- dinucleotide methoxy-6-polyprenyl-1,4- protein] a (3R)-3- U473_RS06360 extension and a GDP purine-nucleoside phosphorylase: (guanine(527)-N(7) nucleoside- U473_RS12580 -CoA ligase: guanosine threonylcarbamoyladenosine(37) phosphate alpha-N- demethylmenaquinone reductase: CoA dehydratase: aminotransferase: [acyl-carrier- [acyl-carrier- carrier-protein] RS13030 a [cysteine 5'-methylthioadenosine/ benzoquinol methylase: dehydratase hydroxyoctadecanoyl- [+ 3 isozymes] short 3' extension ribazoletransferase: phosphorylase: U473_RS04365 )-methyltransferase diphosphate U473_RS08910 cysteine GTP GTP NAD(+) synthase: -C(2))- methylthiotransferase acetylglucosaminyl methyltransferase/2- U473_RS08940 U473_RS08670 U473_RS05860 protein] protein] reductase: desulfurase]-(S- thiamine phosphate S-adenosylhomocysteine U473_RS06040 FabZ: [acp] a (3R,11Z)-3- RNase BN ribonuclease PH: ribonuclease Degradation/ U473_RS10035 U473_RS04365 purine-nucleoside RsmG: kinase: desulfurase: U473_RS02800 purine-nucleoside MtaB: U473_RS03365a 2-methylsulfanyl-N 6 -L- 1-phosphate methoxy-6-polyprenyl-1,4- aldo/keto dehydratase dehydratase U473_RS06360 sulfanyl) -[disordered- 4-(2'- a carboxy- nucleosidase: GTP menaquinol-8 U473_RS11665 3-hydroxyacyl- hydroxy-icos- ribonuclease: P protein Utilization/ an unsulfurated purine-nucleoside U473_RS12600 2-hydroxyglutaryl- aspartate U473_RS06030 RS12220 2 U473_RS09535 U473_RS02425 37 benzoquinol methylase: phosphorylase: 7 carboxyphenyl)- U473_RS01980 cyclohydrolase [acyl-carrier- U473_RS10190 phosphorylase: met 5'-deoxyadenosine threonylcarbamoyladenine GMP adenosylcobalamin transferase: reductase: an N - CoA dehydratase: aminotransferase: FabZ: FabZ: a (3R,5Z)-3-[+ 3 isozymes] form scaffold adenylated GTP 3',8- + 11-enoyl-[acp] component: Assimilation - Other [sulfur carrier] phosphorylase: U473_RS04370 527 dITP 4-oxobutyryl-CoA [+ 2 isozymes] NAD a (2E)-but- xanthosine adenosine inosine guanosine U473_RS04370 in tRNA 5'-phosphate U473_RS11165 6-methoxy-3-methyl-U473_RS06040 9-hydroxy-3,5,7,11,13,15-U473_RS00010 methylguanine U473_RS08770 U473_RS06560 U473_RS11665 a (2E,6Z)-U473_RS11665 hydroxydodec- RS06840 protein] complex [small subunit of an [L-cysteine cyclase MoaA: I FolE: protein] 3-hydroxyacyl- U473_RS12630 α U473_RS04370 5-fluoro-5- S-ribosyl-L- 7,8- 2-enoyl-[acp] acetoacetate UMP lipid I 2-all-trans-octaprenyl- 2-deoxy- - in 16S rRNA (E)-glutaconyl- keto- a (2E)-icos- 1,4-dihydroxy- U473_RS07185 U473_RS06065 dehydratase [acyl-carrier- a tRNA precursor purine-nucleoside hexaoxohexadecanoyl- octadecadienoyl- 5-enoyl-[acp] (2E,6E)-farnesyl molybdopterin desulfurase]-S- homocysteine dihydroneopterin a tRNA degradation D-ribose 1- a purine base deoxy-D-ribose adenine CoA phenylpyruvate 2-enoyl-[acp] 2-naphthoyl- IPP thiamine diphosphate (8S)-3',8-cyclo-7,8- crotonyl-[acyl- FabZ: protein] with a short phosphorylase: 1,4-benzoquinol [PKS-acp] [acp] diphosphate synthase] sulfanyl-L-cysteine 3'-triphosphate menaquinol-6 biosynthesis precursor with (to acetyl CoA) phosphate 1-phosphate RS09640 CoA synthase: dihydroguanosine S-ribosylhomocysteine carrier-protein] U473_RS11665 dehydratase 3' extension purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside U473_RS04365 a [cysteine desulfurase]- a 5' extension RS11675 U473_RS08915 heptaprenyl 5'-triphosphate lyase: U473_RS01975 reductase: FabZ: phosphorylase: phosphorylase: phosphorylase: phosphorylase: acetoacetate [scaffold protein- phosphopantothenate biosynthesis I a (2E)-octadec- 1,4-dihydroxy-2- diphosphate demethylmenaquinol-6 U473_RS09955 U473_RS11665 ribonuclease PH: U473_RS04365 U473_RS04370 U473_RS04370 U473_RS04370 guanine coat protein F: a [formate C adenosylcobinamide- a 2-methyl 2-methoxy-6-all 5'-chloro-5'- an [amino group carrier a (3R,7Z)-3- a (3R,9Z)-3- (S)-1-pyrroline- (2Fe-2S)] complex 2-enoyl-[acp] ribonuclease: a reduced α-ribazole adenosylcobinamide DMKH γ an aldehyde L-cysteate naphthoyl-CoA synthase 7,8- bifunctional U473_RS02425 U473_RS00695 SAM acetyltransferase]- branched 2,3,4- trans-heptaprenyl- 2 protein]-C-terminal- - hydroxy-hexadec- hydroxyhexadec- a thiocarboxylated L-homocysteine a (2E,11Z)-icosa- U473_RS12630 purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside GDP deoxyadenosine 5-carboxylate IDP component II: dihydroneopterin 3-methyl-2-oxobutanoate demethylmenaquinone a butanoyl-[acp] steroyl-[acp] S-methyl-5'- glycine flavodoxin adenosylcobinamide- saturated fatty acid 1,4-benzoquinol bifunctional purine-nucleoside bifunctional (L-glutamyl)-L-glutamate aldehyde ferredoxin aspartate 7-enoyl-[acp] 9-enoyl-[acp] L-glutamate glutathione- [small subunit of cyclic 2,11-dienoyl-[acp] phosphorylase: phosphorylase: phosphorylase: phosphorylase: acetoacetyl-CoA pyruvate formate- long-chain fatty bifunctional 3-hydroxyacyl- 3-hydroxyacyl- RS12035 U473_RS06035 3'-phosphate methyltransferase/2- reductase: thioadenosine degradation I GDP adenosylcobinamide phosphorylase: demethylmenaquinone acetylglutamate oxidoreductase: aminotransferase: gamma- nucleoside- RS05885 glutaredoxin molybdopterin pyranopterin 3-methyl-2-oxobutanoate β U473_RS04370 U473_RS04365 U473_RS04365 U473_RS04365 lyase 1-activating acid--CoA ligase: demethylmenaquinone [acyl-carrier- [acyl-carrier- all-trans- methoxy-6-polyprenyl-1,4- -ketohexanoyl- U473_RS09955 (2E,11Z)-icosa- acetyl-CoA ribazoletransferase: kinase/ U473_RS04365 methyltransferase/2- kinase: U473_RS07225 U473_RS05860 semialdehyde diphosphate a [co-chaperone]- redox reactions synthase] phosphate hydroxymethyltransferase: S-methyl-5'- enzyme: U473_RS08110a 2-methyl methyltransferase/2- protein] protein] 2-carboxy-1,4- heptaprenyl benzoquinol methylase: [acp] synthase: 2,11-dienoyl- α-D-ribose- acetyltransferase: U473_RS10035 adenosylcobinamide- methoxy-6-polyprenyl-1,4- U473_RS10635 dehydrogenase: kinase: [scaffold protein- GSSG U473_RS10545 a stearoyl-[acp] an uncharged xanthine thioadenosine U473_RS01175 a [formate C branched methoxy-6-polyprenyl-1,4- purine-nucleoside an [amino group carrier aldehyde ferredoxin aspartate dehydratase dehydratase naphthoquinol diphosphate molybdopterin U473_RS06040 U473_RS06350 [acp] reductase: 1-phosphate 5'-methylthioadenosine/ U473_RS08055 a flavodoxin AMP diphosphate phosphate benzoquinol methylase: U473_RS00185 U473_RS06030 (2Fe-2S)] complex L-cystathionine 7,8- tRNA met 5'-deoxyadenosine acetyltransferase]- 2,3,4-saturated benzoquinol methylase: phosphorylase: protein]-C-terminal- oxidoreductase: aminotransferase: FabZ: FabZ: guanine RS13950 guanine synthase: 2-dehydropantoate menaquinol-6 3-oxoacyl-[acyl- U473_RS09955 S-adenosylhomocysteine semiquinone GMP adenosylcobalamin guanylyltransferase: U473_RS06040 RS08750 dihydroneopterin phosphopentomutase: acetyl-CoA glycin -2-yl radical fatty acyl-CoA 6-methoxy-3-methyl-2-U473_RS06040 U473_RS04370 γ-(5-phospho-L- U473_RS13930 U473_RS06560 U473_RS11665 U473_RS11665 Glu ITP 1,4-dihydroxy- U473_RS07230 carrier-protein] nucleosidase: U473_RS10040 5-chloro-5- a (2E,7Z)- a (2E,9Z)- U473_RS04360 acetyltransferase: all-trans-heptaprenyl- MQH glutamyl)-L-glutamate a carboxylate 3-sulfopyruvate 2-naphthoate glutathione di-trans,poly-cis dihydroneopterin reductase: a gondoyl-[acp] U473_RS01980 adenosyl-cobinamide adenine deoxyribose 2 hexadeca-2,7- hexadeca-2,9- a [chaperone-ATP]- U473_RS08080 1,4-benzoquinol polyprenyltransferase: -undecaprenyl aldolase: lipoate biosynthesis U473_RS06360 D-ribose 5- urate MTR phosphate 1-phosphate dienoyl-[acp] dienoyl-[acp] RS10215 [co-chaperone]- U473_RS09820 phosphate biosynthesis molybdopterin U473_RS13080 and incorporation I stearate queuosine biosynthesis phosphate acetyl-CoA β a 3-oxohexanoyl- RS06135 [scaffold protein- (2E,6E)-farnesyl cys 6-(hydroxymethyl) -alanine (R)-pantoate S-methyl-5- IPP [acp] long-chain fatty UTP and CTP dephosphorylation I (2Fe-2S)] complex diphosphate -7,8-dihydropterin menaquinol-9 biosynthesis thioribose kinase: a (2R)-2-hydroxy 6-methoxy-2-all- an [RNA]-3'- a (3R,9Z)-3- demethylmenaquinol-7 a reduced an octanoyl-[acp] acid--CoA ligase: preQ 1-myristoylglycerol 1-myristoylglycerol a [ThiI sulfur-carrier 4-phosphooxy- 3-oxoacyl-ACP 0 U473_RS11525 trans-octaprenyl- adenosylcobinamide [DNA] 5-MTR-1-P N5-CAIR di-trans,octa-cis 2-amino-4-hydroxy-6- phosphatidylethanolamine even numbered a palmitoleoyl-[acp] a myristoyl-[acp] cys L-threonine ribonucleoside- AMP asp hydroxy-octadec- glutaredoxin molybdopterin pantoate--beta-alanine octanoyltransferase: reductase: U473_RS08110 NADPH- UTP 3-phosphate 3-phosphate 1,4-benzoquinone bifunctional protein]-L-cysteine DNA polymerase RS01200 bifunctional -undecaprenyl hydroxymethyldihydropteridine demethylmenaquinol-9 biosynthesis I straight chain 2,3,4- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- bifunctional cysteine 4-hydroxythreonine- 2',3'- 9-enoyl-[acp]3-hydroxyacyl- S-methyl-5- 5-(carboxyamino) RS12200 adenine ligase: U473_RS10540 a [lipoyl-carrierU473_RS07580 U473_RS02000 dependent 5-MTR-1-P long-chain fatty adenosylcobinamide bifunctional domain- aspartate demethylmenaquinone glutaredoxin: diphosphate diphosphokinase: U473_RS13085 bifunctional stearoyl-CoA saturated fatty acid 3-phosphate 3-phosphate demethylmenaquinone desulfurase: 4-phosphate cyclophosphate [acyl-carrier- thioribose-1- imidazole a [chaperone- dinucleotide protein] N 6 - 7-cyano-7- CTP synthase: acid--CoA ligase: kinase/ RNA 2',3'-cyclic metallophosphatase/ containing aminotransferase: an [2Fe-2S] methyltransferase/2- U473_RS03635 undecaprenyl- (7,8-dihydropterin- demethylmenaquinone [+ 3 isozymes] a CDP-diacylglycerol acyltransferase: acyltransferase: methyltransferase/2- U473_RS12580 dehydrogenase protein] phosphate ribonucleotide ADP]-[disordered- molybdopterin adenosylcobalamin octanoyl-L-lysine a (3R)-3- deazaguanine U473_RS11975 aU473_RS08110 (R)-2-hydroxy even adenosylcobinamide- phosphodiesterase: 5'-nucleotidase: protein: U473_RS05860 cluster protein methoxy-6-polyprenyl-1,4- two reduced diphosphatase: 6-yl)methyl (R)-pantothenate methyltransferase/2- CDP-diacylglycerol--serine U473_RS06125 U473_RS06125 methoxy-6-polyprenyl-1,4- cysteine PdxA: dehydratase isomerase: mutase: form scaffold molybdenumtransferase salvage from cobalamin hydroxyhexanoyl- reductase QueF: UMP Secondary Metabolite Degradation numbered straight 1-myristoyl-2- phosphate an [RNA]-3'-U473_RS07135 U473_RS02020 U473_RS05895 aspartate benzoquinol methylase: cysteine residues U473_RS07825 diphosphate methoxy-6-polyprenyl-1,4- O-phosphatidyltransferase: diphosphate AMP dimyristoyl benzoquinol methylase: desulfurase: U473_RS08245 FabZ: U473_RS11510 U473_RS00020 RS00190 RS06745 protein] complex MoeA: U473_RS07210 pantothenate kinase: [acp] U473_RS08790 CTP chain 2,3,4-saturated acyl-carrier protein palmitoleoyl acyl-carrier protein guanylyltransferase: 3-amino-1- ribunucleoside- a nucleoside 5'- aminotransferase: 5-(methylthio) U473_RS06040 in a protein undecaprenyl- MoO - cob(I)alamin benzoquinol methylase: a 3-sn-phosphatidyl-U473_RS13155 bifunctional fatty acyl CoA phosphatidate phosphatidate 3-methyl-6-methoxy-U473_RS06040 U473_RS09535 hydroxyacetone adenosine U473_RS11665 ribulose 1- CAIR 2 preQ pseudouridine a [ThiI sulfur- 2'-phosphate U473_RS06560 a (2E,9Z)- U473_RS13065 a [lipoyl-carrier U473_RS06040 3-hydroxyacyl- 1 anhydromuropeptides recycling I U473_RS10040 monophosphate diphosphatase: molybdopterin ATP:cob(I)alamin biotin-carboxyl carrier L-serine metallophosphatase/ degradation 2-octaprenyl-1,4- ala carrier protein]-S- 1-phosphate oxaloacetate octadeca-2,9- phosphate menaquinol-7 protein]-N 6 - menaquinol-9 [acyl-carrier- adenosyl-cobinamide U473_RS12740 cofactor adenosyltransferase: (R)-4'-phosphopantothenate protein assembly phosphatidylserine 5'-nucleotidase: GlcNAc-1,6- benzoquinone sulfanyl-L-cysteine dienoyl-[acp] an [Fe-S cluster a [disordered- di-trans,octa-cis lipoyl-L-lysine protein] U473_RS02020 CMP phosphate RS11890 U473_RS00955 dehydratase a [biotin decarboxylase: pseudouridine anhMurNAc- RS02080 biosynthesis form [Fe-S] cluster -undecaprenyl adenosylcobalamin FabZ: carboxyl-carrier U473_RS13150 a 7-aminomethyl-7- pyrimidine deoxyribonucleotides uridine bifunctional pseudouridine L-Ala-γ-D-Glu- chaperone]-ATP scaffold protein] phosphate 34 protein]-L-lysine deazaguanosine metallophosphatase/ kinase: DAP-D-Ala a (2'R)-2'- 1-stearoyl- a peptide with a 2'- (E)-4-hydroxy-3- a 3- a (7Z)-3-oxo- a (3R,11Z)-3- U473_RS11665 an L-1- dephosphorylation a 1-phosphatidyl- 1-palmitoylglycerol 1-palmitoylglycerol a supercoiled biotin--[acetyl- in tRNA 5'-nucleotidase: U473_RS03915 hydroxy- a palmitoleoyl-[acp] a myristoyl-[acp] a palmitoyl-[acp] sn-glycerol an N-terminal deoxyribonucleoside [DNA] L-allo-threonine methylbut-2-en- oxodocosanoyl- hexadec-7- hydroxyoctadec- a protein a (2E)-hex- phosphatidylethanolamine NTP pyrophosphohydrolase: pseudouridine 1D-myo-inositol 3-phosphate 3-phosphate ATP H O duplex DNA CoA-carboxylase] tRNA preQ1(34) S- 2 RS01230 U473_RS03370 U473_RS02020 phytoceramide inositol 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol-3-phosphate Xaa-L-prolineleucyl 5'-triphosphate DNA polymerase low-specificity 1-yl diphosphate4-hydroxy-3- [acp] 3-oxoacyl-ACP enoyl-[acp]3-oxoacyl-[acyl- 11-enoyl-[acp]3-hydroxyacyl- helicase: HslU--HslV 2-enoyl-[acp] ligase: adenosylmethionine dCTP dCMP 5'-phosphate ATPase: RS08765 pyrimidine cytidine phosphorylceramide 3-phosphate 3-phosphate 3-phosphate aminopeptidase: domain- L-threonine methylbut-2-en-1- reductase: carrier-protein] [acyl-carrier- U473_RS07730 peptidase hexanoyl-[acyl- U473_RS05930 ribosyltransferase- N-acetyl-β-D- L-alanyl-γ-D- U473_RS05875 replicative a [biotin carboxyl- ribonucleosides pseudouridine- synthase: acyltransferase: acyltransferase: acyltransferase: U473_RS06990 containing aldolase: yl diphosphate U473_RS02000 reductase: protein] ATPase subunit: Nucleoside and Nucleotide Biosynthesis carrier-protein] isomerase QueA: glucosamine-1,6- glutamyl-meso-2,6- ATPase: DNA helicase: carrier protein]-N deoxyuridine degradation 5-phosphate a very-long-chainU473_RS02955 U473_RS061251-palmitoyl-2- U473_RS061251-palmitoyl- U473_RS061251-stearoyl- leucyl protein: U473_RS03060 synthase: a (3R)-3-[+ 3 isozymes] U473_RS06360 dehydratase U473_RS06185 reductase: U473_RS02940 anhydro-N-acetyl- diaminopimeloyl- a 1,2-diacyl- U473_RS11700 U473_RS12490 RS11995 6 5'-triphosphate cytidine glycosidase: inositol phospho-(2'R)- aminopeptidase: U473_RS05895 2-C-methyl-D-U473_RS04810 [+ 3 isozymes] FabZ: -biotinyl-L-lysine β acyl-carrier protein palmitoleoyl acyl-carrier protein 2-myristoyl 2-palmitoyl- + acetaldehyde gly hydroxydocosanoyl- a (3R,7Z)-3- a single a peptide UMP biosynthesis III U473_RS09955 an epoxyqueuosine 34 cytidine U473_RS03920 -D-muramate D-alanine sn-glycerol acyl-carrier protein H phosphate ADP superpathway of adenosine pyrimidine deoxyribonucleotides de novo biosynthesis III superpathway of pyrimidine deoxyribonucleoside salvage nucleotidohydrolase: 2'-hydroxyphytoceramide phosphatidate phosphatidate sn-glycerol a peptide with U473_RS09080 [+ 7 isozymes] erythritol-2,4- [acp] hydroxy-hexadec- a (2E,11ZU473_RS11665)- RS02160 superpathway of guanosine guanine and xanthine and in tRNA deaminase: a proteinogenic stranded DNA nucleotides de novo biosynthesis I U473_RS04885 uracil 3-phosphate an N-terminal [DNA] cyclodiphosphate 7-enoyl-[acp] octadeca-2,11- nucleotides de novo biosynthesis I guanosine salvage xanthosine salvage a hexanoyl-[acp] U473_RS03460 amino acid UDP CTP 2'-deoxycytidine epoxyqueuosine NTP pyrophosphohydrolase: L-proline dienoyl-[acp] RS02730 gln hydrogencarbonate a [biotin carboxyl- reductase: uridine L-alanyl-γ-D- 3-oxoacyl-[acyl- carrier-protein fatty acid elongation -- saturated U473_RS03370 1,6-anhydro-N- IMP IMP asp cytidine deaminase: guanosine U473_RS01075 dUTP dUMP uridine acetyl-β-muramate glutamyl-meso- xanthosine carrier-protein] dimer]-N 6 - 1-cis- carbamoyl dUDP CDP 34 diaminopimelate 1-cis- 1-stearoyl- an [apo BCAA a (7Z,10Z,13Z,16Z (1S,2R)-1- 1939 a 3- a (3R,5Z)-3- a SpoIVB RS02625 U473_RS03460 purine-nucleoside a queuosine phosphorylase: S-methyl-5'-thioadenosine 2-(2-carboxy-4-methylthiazol- 1-palmitoylglycerol a uracil a cis-delta21-3- phosphate purine-nucleoside reductase: biotinyl-L-lysine HMP-PP a palmitoleoyl-[acp] vaccenoylglycerol- a palmitoyl-[acp] a stearoyl-[acp] sn-glycerol 4-methyl-2- dehydrogenase ,19Z)-3-oxodocosa- C-(indol-3- vaccenoylglycerol- oxodocosanoyl- hydroxy-tetradec- leu peptidase IMP nucleoside-diphosphate phosphorylase: an acetoacetyl-[acp] in tRNA U473_RS11200 degradation IV 5-yl)ethyl phosphate 3-phosphate ser in 23S rRNA oxo-C40:1-[acp] synthase dCMP phosphorylase: U473_RS06360 acetyl-CoA 5-hydroxy-CTP 5-hydroxy-CMP thiamine phosphate 3-phosphate 3-phosphate oxopentanoate E2 protein] N 6 7,10,13,16,19-pentaenoyl-[acp]3-oxoacyl-ACP yl)glycerol 3-phosphate 23S rRNA [acp] 3-oxoacyl-ACP 5-enoyl-[acp] 3-oxoacyl-ACP Precursor RS03320 dehydrogenase: kinase: U473_RS06030 2'-deoxyuridine U473_RS04370 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 3-oxoacyl-[acyl- leucine SpoIVB large subunit: cytidylate kinase: U473_RS04365 β-ketooctanoyl- carboxylase uracil S-methyl-5'- N-acetyl-D- synthase: U473_RS05315 branched-chain-lipoyl-L-lysine reductase: 3-phosphate tryptophan (uracil(1939)-C(5)) reductase: reductase: U473_RS12685 purine-nucleoside 3-phosphate 3-phosphate 3-phosphate 3-phosphate carrier-protein] dehydrogenase: peptidase: U473_RS06630 dUTP dCDP U473_RS06130 purine-nucleoside [acp] synthase: carboxyl thioadenosine muramate 6- thiamine phosphate alpha-keto acid U473_RS02000 synthase -methyltransferase U473_RS02000 U473_RS02000 a sugar RS07540 a sugar adenylo-succinate thymidine kinase: phosphorylase: 5'-methylthioadenosine/ acyltransferase: acyltransferase: acyltransferase: acyltransferase: reductase: U473_RS04180 U473_RS04135 phosphorylase: U473_RS06350 transferase phosphate synthase: U473_RS06245 dehydrogenase subunit beta: RlmD: [+ 2 isozymes] XMP deoxyuridine nucleoside-diphosphate U473_RS11935 dCDP U473_RS04365 acetyl-CoA 5-oxo-L-proline metabolism S-adenosylhomocysteine U473_RS061251-cis-vaccenoyl- U473_RS06125 U473_RS061251-stearoyl-2- a (3R,7Z,10Z,13[+Z ,163 isozymes]Z 1,2-dicis- U473_RS06125 a (3R)-3-[+ 3 isozymes] U473_RS06360 leucine a cis-delta21-3-[+ 3 isozymes] U473_RS04370 subunit beta: N-acetylmuramic dipalmitoyl subunit E2: U473_RS08125 U473_RS00230 a SpoIVB RS06830 carbamoyl 5'-triphosphate kinase: U473_RS06030 thymidine guanine xanthine a 3-oxooctanoyl- carboxylase a 3-oxoacyl-[acp] nucleosidase: thiamine phosphate acyl-carrier protein 2-palmitoleoyl acyl-carrier protein stearoyl-sn a [apo BCAA dehydrogenase ,19Z)-3-hydroxydocosa- D-glyceraldehyde vaccenoyl- a 5- hydroxydocosanoyl- a (5Z)-3-oxo-[+ 3 isozymes] dehydrogenase: hydroxyC40:1- a sugar RS02230 a sugar asp nucleoside- U473_RS01295 an N-terminal acid 6-phosphate phosphatidate acyl-carrier protein U473_RS04230 trp peptidase phosphate nucleotidohydrolase: dCTP dUMP [acp] biotin carboxylase U473_RS01980 phosphatidate -glycerol 3- E2 protein] N 6 -S-[3- 7,10,13,16,19-pentaenoyl-[acp] 3-phosphate phosphatidate methyluracil 1939 [acp] tetradec-5- U473_RS13965 [acp] xanthosine-5'- diphosphate kinase: acetyl-CoA L-glutaminyl- an N-terminal L- etherase: U473_RS04885 hypoxanthine 3-oxoacyl-ACP subunit: MTR phosphate methylbutanoyl]dihydrolipoyl- in 23S rRNA enoyl-[acp] 4-methyl-2- phosphate:L- thymidine kinase: U473_RS06030 carboxylase [protein] glutamyl-[protein] U473_RS09695 NTP phosphoribosyltransferase: reductase: U473_RS04060 3-oxoacyl-[acyl- N-acetyl-D- L-lysine oxopentanoate a sugar RS08460 a sugar aspartate glutamine AMP U473_RS11935 carboxyl RS02620 pyrophosphohydrolase: dCTP U473_RS13050 U473_RS02000 carrier-protein] glucosamine carbamoyltransferase: amido-ligase superpathway of 5-aminoimidazole transferase U473_RS03370 reductase: 6-phosphate 6 U473_RS06645 (AMP-forming): ribonucleotide biosynthesis XMP [+ 3 isozymes] subunit alpha: an N -L- an odd numbered a 3-methyl- 2-phospho-4-(cytidine 5'- an [apo BCAA a [2-oxoglutarate 1-cis- 2-phospho- a (9Z)-3-oxo- a double a sugar RS11530 a sugar 37 a reduced a cis-delta19-3- U473_RS13945 adenylate kinase: GMP a (3R)-3- β U473_RS06360 a [protein] with N-acetylglucosamine- threonylcarbamoyladenine straight chain branched 2,3,4- diphospho)-2-C-methyl-D-erythritol (S)-3-methyl-2- dehydrogenase NADP + H + dehydrogenase E2 protein] vaccenoylglycerol- MEP octadec-9- ala dUMP dTMP U473_RS01300 -ketoacyl- adrenodoxin D-glycerate stranded DNA oxo-C38:1-[acp] U473_RS13400 PRPP hydroxyoctanoyl- a [carboxyl-carrier [+ 3 isozymes] an N-terminal 5- Carbohydrate Degradation 6-phosphate in tRNA 2,3,4-saturated saturated fattylong-chain acid fatty 2-C-methyl-D- oxopentanoate E2 protein] N 6 N 6 -dihydrolipoyl-L-lysine 3-phosphate1-acyl-sn-glycerol- phosphoglycerate 1-deoxy-D-xylulose- enoyl-[acp]3-oxoacyl-[acyl- DNA gyrase 3-oxoacyl-ACP RS03960 N-carbamoyl- thymidylate synthase ACP synthase: tRNA ferredoxin- dihydrolipoyl alanine a sugar RS12270 a sugar GMP amidophosphoribosyltransferase: dTMP kinase: [acp] protein dimer]-N 6 a (3R)-3- oxo-L-proline deacetylase: fatty acidlong-chain fatty acid--CoA ligase: erythritol 2,4- -lipoyl-L-lysinebranched-chain 3-phosphate mutase (2,3- 5-phosphate carrier-protein] subunit B: reductase: L-aspartate (FAD): U473_RS09445 U473_RS06350 γ-L-glutamyl threonylcarbamoyladenosine -NADP(+) dehydrogenase: racemase: U473_RS00050 U473_RS12810 3-hydroxyacyl- -carboxybiotinyl- a 2,3,4-saturated hydroxyacyl-[acyl- glutathione U473_RS09710 acid--CoA ligase: U473_RS08110 cyclodiphosphate alpha-keto acid acyltransferase: diphosphoglycerate- reductoisomerase: reductase: U473_RS12665 U473_RS02000 ADP 5-phospho-β- superpathway of pyrimidine 5-phosphate D-galactose degradation I (Leloir pathway) dehydratase: U473_RS03040 an odd numbered a 3-methyl- reductase: U473_RS08650 U473_RS13730 dihydroorotase: dTMP [acyl-carrier- fatty acyl-[acp] pyroglutamyl- sucrose degradation IV (sucrose phosphorylase) D-glucosamine 6 U473_RS08110 synthase: dehydrogenase independent): dTDP L-lysine carrier protein] a cyclic N -L- straight chain branched U473_RS09120 a [2-oxoglutarate[+ 2 isozymes] 1-cis-vaccenoyl-U473_RS06125 1-deoxy-D-U473_RS04800 U473_RS06360 DNA gyrase a cis-delta19-3-[+ 3 isozymes] a sugar RS09860 a sugar U473_RS06640 guanylate kinase: D-ribosylamine nucleobases salvage protein] peptidase I: 6-phosphate diphosphate AMP diphosphate AMP U473_RS13175 subunit E2: an oxidized U473_RS10300 dTMP kinase: pyrimidine 3-hydroxyacyl- β threonylcarbamoyladenosine 2-palmitoleoyl xylulose 5- [+ 3 isozymes] subunit A: D-ala RS07385 U473_RS06545 phosphoribosylamine- nucleoside- adenine and dehydratase U473_RS05745 -D-galactose 2,3,4-saturated 2,3,4-saturated an [apo BCAA dehydrogenaseU473_RS04230 NADPH dehydrogenase E2 3-phospho- a (3R,9Z)-3- hydroxyC38:1- uracil sucrose 37 in tRNA 2-C-methyl-D-erythritol- 6 adrenodoxin 6 U473_RS12670 F0F1 ATP U473_RS12810 ribonucleosides salvage I [acyl-carrier- phosphoglucosamine fatty acyl CoA fatty acyl-CoA CMP E2 protein] N -S-[2- protein] N -lipoyl-L-lysine phosphatidate phosphate hydroxy-octadec- [acp] (S)-dihydroorotate -glycine ligase: diphosphate kinase: bifunctional pyr operon adenosine salvage I FabZ: galactose-1- 2,4-cyclodiphosphate D-glycerate a negatively a sugar RS11625 a sugar synthase dTDP protein] mutase: U473_RS13565 methylbutanoyl]dihydrolipoyl- 9-enoyl-[acp] GDP U473_RS00070 U473_RS06030 transcriptional regulator/uracil cytidine U473_RS11665 epimerase: supercoiled DNA dihydroorotate subunit epsilon: long-chain fatty dehydratase 5-oxo-L-proline sucrose D-glucosamine L-lysine nucleoside-diphosphate dTTP phosphoribosyltransferase: a (2E)-oct- U473_RS08415 RS02830 dehydrogenase U473_RS11815 GAR adenosine acid activation FabZ: phosphorylase: 1-phosphate a sugar RS04965 a sugar dADP kinase: U473_RS06030 U473_RS06655 cytidine 2-enoyl-[acp] electron [+ 8 isozymes] purine-nucleoside U473_RS11665 α-D-galactose U473_RS11610 RNase III mRNA a (7Z)-3- phosphoribosylglycinamide uracil deaminase: a long-chain UDP-N- 1-stearoyl- 1-cis- 2-methylacetoacetyl- an apo-[LYS2 L- 1-myristoylglycerol transfer subunit: nucleoside- dTTP phosphorylase: octanoyl-[acyl- a trans-2- NaMN 5,6-dimethylbenzimidazole a cis- processing L-threo-3- a 3-oxohexacosanoyl- palmitoleoyl-CoA oxotetradec- GGPP IPP a cis-delta17-3- histidinol nucleoside- formyltransferase: CMP U473_RS03460 fatty acid a 2,3,4-saturated α acetylglucosamine an oleoyl-[acp] sn-glycerol vaccenoylglycerol- CoA 2-aminoadipyl- coenzyme A 3-phosphate diphosphate phosphoribosyltransferase: U473_RS04370 carrier-protein] long-chain fatty enoyl-[acyl- β -D-glucopyranose vaccenoyl-[acp] phenylserine [acp] oxo-C36:1-[acp] predicted U473_RS06625 diphosphate U473_RS00060 fatty acyl-[acp] galactokinase: -D-fructofuranose diphosphorylase/ nicotinate-nucleotide-- 1-acyl-sn-glycerol-3-phosphate 1-acyl-sn-glycerol-3-phosphate substrateribonuclease III: acetyl-CoA carrier-protein] holo-[acyl- low-specificity 1-acyl-sn-glycerol- 3-oxoacyl-ACP acyl-CoA 7-enoyl-[acp]3-oxoacyl-[acyl- heptaprenyl 3-oxoacyl-ACP histidinol kinase: U473_RS11870 purine-nucleoside reductase: acid--CoA ligase: carrier protein] Glu 1-phosphate ABC RS03315 PRPP ATP kinase: CMP UMP uridine U473_RS08430 glucosamine-1- dimethylbenzimidazole 3-phosphate 3-phosphate U473_RS06345 acetyltransferase: carrier-protein] L-threonine 3-phosphate reductase: dehydrogenase: carrier-protein] diphosphate reductase: dehydrogenase: a sugar a sugar orotate U473_RS06030 dGDP phosphorylation FGAR phosphorylase: U473_RS09955 U473_RS08110 phosphoglucomutase: phosphoribosyltransferase: U473_RS08055 U473_RS08050 transporter U473_RS06030 uridine kinase: a long-chain 2,3,4-saturated α-D-galactose phosphate N- acyltransferase: acyltransferase: ribonuclease III: synthase: aldolase: acyltransferase: U473_RS02000 reductase: synthase U473_RS02000 U473_RS10435 of a sugar cytidylate kinase: U473_RS04365 fatty acyl-CoA UDP-α-D-glucose fructokinase: U473_RS05720 acetyltransferase: U473_RS10055 acetyl-CoA U473_RS06125 [+ 2 isozymes] component II: orotate CMP U473_RS03150 fatty acyl- 1-phosphate α U473_RS061251-stearoyl-2- U473_RS061251,2-dicis- U473_RS13195RNase III a holo-[LYS2 L- U473_RS13710 U473_RS03060 1-myristoyl-2- a (3R)-3-[+ 3 isozymes] U473_RS06360 a cis-delta17-3-[+ 3 isozymes] nucleoside- phosphoribosylformylglycinamidine U473_RS06130 adenine an octanoyl-[acp] -ribazole (2E,9Z)- his a sugar RS00620 a sugar phosphoribosyltransferase: dATP cytidylate kinase: [acp]:NAD+ U473_RS11615 D-glucopyranose U473_RS12915 nicotinate acyl-carrier protein oleoyl-sn-glycerol acyl-carrier protein vaccenoyl- an mRNA fragment processing acetyltransferase: 2-aminoadipyl- 3',5'-ADP gly benzaldehyde palmitoleoyl hydroxyhexacosanoyl- a (3R,7Z)-3-[+ 3 isozymes] all-trans-U473_RS06035 hydroxyC36:1- GTP diphosphate synthase subunit PurS: U473_RS00035 UMP α 5'-phosphate hexadecenoyl-CoA RS09340 U473_RS06610 U473_RS06130 UDP oxidoreductase: 6-phosphate N-acetyl- -D- 3-phosphate phosphatidate product mRNA U473_RS08080 carrier-protein] phosphatidate [acp] hydroxytetradec- heptaprenyl [acp] kinase: [+ 2 isozymes] adenine 3-oxoacyl-[acyl- CDP nucleoside-diphosphate U473_RS09955 Respiration glucose-6- glucosamine acetyl-CoA propanoyl-CoA 7-enoyl-[acp] diphosphate predicted U473_RS06030 phosphoribosyltransferase: carrier-protein] FGAM kinase: U473_RS06030 phosphate 1-phosphate ABC orotidine 5'- nucleoside- U473_RS03000 reductase: a sugar a sugar phosphate diphosphate UTP U473_RS06360 2-oxoisovalerate decarboxylation to isobutanoyl-CoA isomerase: UDP-N- transporter RS10470 dGTP phosphoribosylformylglycinamidine a 1-acyl-sn kinase: β U473_RS00760 acetylglucosamine a 1-acyl-sn 3-oxopentanoyl- 1-palmitoylglycerol (7Z)- of a sugar CTP synthase: AMP -ketodecanoyl- an [apo BCAA phosphatidylglycerophosphate an acyl-[acyl- a cis- 1-palmitoylglycerol an acyl-[acyl- an acyl- a 3-oxotetracosanoyl- a cis-delta15-3- arsenate U473_RS06030 cyclo-ligase: U473_RS00055 diphosphorylase/ a malonyl-[acp] -glycerol 3- CoA coenzyme A thr 3-phosphate hexadecenoyl-CoA IMP -glycerol 3- a sugar RS07545 a sugar U473_RS11975 [acp] synthase: dehydrogenase (1-octadecenoyl(9Z), 2-palmitoyl) carrier protein] vaccenoyl-[acp] 3-phosphate carrier protein] carrier protein [acp] oxo-C34:1-[acp] F6P glucosamine-1- phosphatidylglycerophosphatase 3-oxoacyl-[acyl- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol-phosphate acetyl-CoA holo-[acyl- low-specificity 1-acyl-sn-glycerol- 3-oxoacyl-ACP acyl-CoA phosphate1-acyl-sn-glycerol- 3-oxoacyl-ACP arsenate CTP AIR U473_RS06350 E2 protein] N 6 3-methyl-2- bifunctional UMP CTP phosphate N- A: U473_RS09235 carrier-protein] 3-phosphate 3-phosphate acetyltransferase: carrier-protein] L-threonine 3-phosphate reductase: dehydrogenase: 3-phosphate reductase: reductase oxobutanoate 2+ 2+ RS11785 a 3-oxodecanoyl- -lipoyl-L-lysine ribose acetyltransferase: U473_RS08080 acyltransferase: U473_RS02000 U473_RS08050 metallophosphatase/ U473_RS02000 (thioredoxin): Mg RS07460 Mg dehydrogenase phosphatidylglycerophosphatase reductase: acyltransferase: acyltransferase: synthase: aldolase: acyltransferase: [acp] 3-methyl-2- phosphorylation U473_RS12915 acetyl-CoA U473_RS06125 [+ 2 isozymes] 5'-nucleotidase: U473_RS08600 subunit VorB: A: U473_RS07140 U473_RS06360 U473_RS061251-palmitoyl-2- U473_RS06125a 1,2-diacyl- U473_RS13710 U473_RS03060 1-palmitoyl-2- a (3R)-3-[+ 3 isozymes] a 1-acyl-2-U473_RS06125 a cis-delta15-3-[+ 3 isozymes] Aminoacyl-tRNA Charging oxobutanoate 1-oleoyl-2-palmitoyl- acetyltransferase: (2E,7Z)- U473_RS02020 arsenite 3-oxoacyl-ACP UDP-N-acetyl- cis-vaccenoyl palmitoyl-sn 2+ 2+ dehydrogenase U473_RS04200 β-D-ribopyranose phosphatidylglycerol acyl-carrier protein a 3-oxoacyl-[acp] acyl-carrier protein cis-vaccenoyl acyl-carrier protein sn-glycerol acyl-carrier protein 3',5'-ADP gly acetaldehyde hydroxytetracosanoyl- hexadecenoyl-CoA hydroxyC34:1- Mg RS08530 Mg reductase: UDP-glucose:α- α-D-glucosamine U473_RS08055 phosphatidate inosine -glycerol 3- RS13395 subunit VorB: [+ 3 isozymes] UDP-glucose D-ribose phosphatidate 3-phosphate [acp] [acp] Amino Acid Biosynthesis U473_RS02000 tRNA charging D-galactose- UDP-N-acetylglucosamine propanoyl-CoA acetyl-CoA phosphate gln U473_RS04200 pyranase: [+ 3 isozymes] glutaminyl-tRNA 4-epimerase: 1-carboxyvinyltransferase: an [apo BCAA 1-phosphate U473_RS09275 a (3R)-3- biosynthesis via [+ 5 isozymes] U473_RS07640 RS11195 L-histidine biosynthesis arginine-- dehydrogenase an [apo BCAA dehydrogenase uridylyltransferase: β-D-ribofuranose U473_RS06815 superpathway of L- superpathway of branched chain amino acid biosynthesis L-arginine biosynthesis II (acetyl cycle) L-lysine biosynthesis VI superpathway L-methionine biosynthesis III hydroxydecanoyl- arg transamidation 6 [+ 4 isozymes] tRNA ligase: 6 E2 protein] N -S-[2- α U473_RS08420 [+ 2 isozymes] 1-stearoyl- a reduced 1402 a 1-alkyl-sn a [lipoyl-carrier D-ribulose RS01690 E2 protein] N -D-glucopyranose α quinoxaline-2- an acyl-[acyl- a cytidine 1-palmitoylglycerol a 3-oxopimeloyl- a cis-delta13-3- isoleucine biosynthesis I of L-threonine [acp] methylpropanoyl]dihydrolipoyl- UDP- -D-galactose α 16-hydroxypalmitate acyl-carrier protein + + DMKH2-10 -glycerol 3- cis-vaccenoyl-CoA 6 PRPP U473_RS09410 an L-arginyl- Glu -dihydrolipoyl- 1-phosphate UDP-N-acetyl- - sn-glycerol ferredoxin [iron- NADP H VibB coenzyme A in 16S rRNA 3-phosphate protein]-N -[(R) 5-phosphate pyruvate N-acetylglutamyl- biosynthesis 3-hydroxyacyl- L-lysine long-chain fatty carboxyl adenylate carrier protein] 16S rRNA phosphate acyl-CoA [acp] methyl ester oxo-C32:1-[acp] ribulose- thr L-homoserine [tRNA Arg ] L-lysine chitobiose degradation D-glucosamine- acyl carrier 1-acyl-sn-glycerol-3-phosphate sulfur] cluster ferredoxin- bifunctional holo-[acyl- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 3-oxoacyl-ACP -dihydrolipoyl]- 3-oxoacyl-ACP oxaloacetate phosphate asp a cation RS03695 a cation ATP oxaloacetate homoserine O- [acyl-carrier- a tRNA Arg phosphoglucomutase: enolpyruvate acid--CoA ligase: protein: demethylmenaquinone (cytidine(1402)-2'-O) 3-phosphate 3-phosphate dehydrogenase: reductase: L-lysine dihydrolipoyl reductase: phosphate 3- aspartate acetolactate aspartate kinase: α-D-ribofuranose 3-phosphate -NADP(+) carrier-protein] phosphoribosyltransferase: aspartate protein] U473_RS05720 N,N'- U473_RS08110 U473_RS06355 methyltransferase/2- -methyltransferase: acyltransferase: U473_RS08050 U473_RS02000 dehydrogenase: U473_RS02000 epimerase: RS04235 aminotransferase: U473_RS04915 acetyltransferase: an L-glutamyl- UDP-N- acyltransferase: reductase: synthase: acyltransferase: synthase dehydratase Gln maltose degradation a quinoxaline-2- U473_RS12850 U473_RS06490 U473_RS10440 aminotransferase: U473_RS12160 [tRNA ] D-glucopyranose diacetylchitobiose ribokinase: acetylenolpyruvoylglucosamine 16-hydroxypalmitoyl- U473_RS06125 U473_RS09120 methoxy-6-polyprenyl-1,4- U473_RS13710 a 2'-O- 1-palmitoyl-2-U473_RS06125 a 2-acyl-1-alkyl-U473_RS06125 [+ 2 isozymes] [+ 3 isozymes] U473_RS04215 [+ 3 isozymes] a cation RS06875 a cation U473_RS05860 small subunit: N-acetyl- aspartate kinase: O-acetyl-L- FabZ: 3-methyl-2- AMP diphosphate AMP carboxyl-[aryl- a 1-stearoyl 2- an oxidized (2E,11Z)- a (3R)-3- a cis-delta13-3- D-xylulose ATP bifunctional U473_RS05860 hydrogen sulfide 6-phosphate 6'-phosphate U473_RS09280 reductase: U473_RS06820 CoA benzoquinol methylase: a holo-[VibB aryl- methylcytidine 1402 palmitoleoyl sn-glycerol a [lipoyl-carrier[+ 2 isozymes] aspartate U473_RS08385 gamma-glutamyl- U473_RS02320 homoserine aspartyl/glutamyl- carrier protein] acyl-carrier protein acyl-sn-glycerol NADPH ferredoxin [iron- 3',5'-ADP octadecenoyl-CoA hydroxypimeloyl- 6 hydroxyC32:1- 5-phosphate (2Z)-2-aminobut- L-aspartyl- U473_RS11665 oxobutanoate maltose U473_RS06040 carrier protein] protein]-N - phosphoribosyltransferase aminotransferase: ornithine phosphate aspartate cysteine-- tRNA(Asn/Gln) N-monoacetylchitobiose α-D-ribose UDP-N-acetyl- 3-phosphate sulfur] cluster in 16S rRNA phosphatidate 3-phosphate [acp] methyl ester [acp] taurine RS02095 taurine acetolactate 2-enoate 4-phosphate O-acetylhomoserine cys dehydrogenase maltose α lipoyl-L-lysine an anion RS08615 an anion regulatory subunit: U473_RS06560 acetyltransferase/ reductase: aminotransferase: a (2E)-dec- tRNA ligase: amidotransferase 6'-phosphate 5-phosphate -D-muramate menaquinol-10 synthase, N-acetylglutamate acetylglutamate U473_RS06560 aminocarboxypropyltransferase: 2-enoyl-[acp] subunit VorB: phosphorylase: U473_RS10445 U473_RS10645 aspartate- U473_RS13190 an L-cysteinyl- subunit C: predicted asp large subunit, synthase: kinase: U473_RS03255 U473_RS04200 U473_RS05420 6-phospho-beta- 1-(5-phospho- asp decanoyl-[acyl- [tRNA Cys ] U473_RS00205 β-D-glucopyranose ABC biosynthetic type: U473_RS10635 N-acetyl-L- semialdehyde [+ 3 isozymes] fructose degradation glucosidase: an [amino group carrier protein]- an anion RS03160 an anion D-ribose D-ribose β U473_RS10640 N-acetyl-L- a tRNA Cys phosphoenol an [HPr]- 1-[18-hydroxyoleyl]- 2-dehydro- (7Z)- (3R,5S)-3- D-ribose 5- transporter -D-ribosyl)-ATP aspartate kinase: U473_RS08390 2-iminobutanoate Glu glutamate 5- dehydrogenase: L-homocysteine carrier-protein] [+ 2 isozymes] 1-phosphate U473_RS00510 UDP-N-acetyl- 18-hydroxystearate γ DMKH2-11 [EntF L-seryl- 1-palmitoylglycerol a 3-oxoglutaryl- a cis-delta11-3- glutamate aspartate kinase: β pyruvate L-histidine C-terminal- -(L-glutamate 5- coenzyme A 2-lyso-phosphatidate 3-deoxy-D- tetradecenoyl-CoA hydroxy-1- phosphate bifunctional U473_RS04915 semialdehyde U473_RS04910 reductase: -D-fructofuranose beta- N-acetyl-D- trehalose degradation I (low osmolarity) α-D-muramoyl- hypoxanthine PRPP carrier protein] 3-phosphate [acp] methyl ester oxo-C30:1-[acp] of D-ribose U473_RS04915 an L-glutaminyl- long-chain fatty phosphoenolpyruvate- semialdehyde-2-yl)-L-glutamateN-acetyl-gamma- bifunctional 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- gluconate acyl-CoA 3-oxoacyl-ACP pyrroline-5- 3-oxoacyl-ACP ribose 5- glycine glycine lactate RS04545 lactate (S)-2-acetolactate methionine methionine U473_RS09955 Gln 1-phosphate phosphoglucomutase: γ holo-[acyl- RS07840 phosphoribosyl- aspartate kinase: L-aspartate- [tRNA ] glucosamine D-glucosamine L-alanyl- -D- acid--CoA ligase: hypoxanthine -protein demethylmenaquinone 3-phosphate 2-dehydro-3- dehydrogenase: carboxylate phosphate betaine betaine aspartate kinase: synthase: synthase: 1-phosphofructokinase: U473_RS05715 α,α-trehalose glutamyl-phosphate carrier-protein] 3-phosphate reductase: pyrroline-5- reductase: AMP U473_RS02320 semialdehyde glyoxylate cycle 6-phosphate glutamyl-meso-2,6- U473_RS08110 phosphoribosyltransferase: phosphotransferase: methyltransferase/2- acyltransferase: deoxygluconokinase: U473_RS08050 isomerase B: 2+ 2+ ketol-acid U473_RS02320 U473_RS09385 U473_RS09385 a decanoyl-[acp] β U473_RS02930 β 6-phosphate reductase: synthase: acyltransferase: U473_RS02000 carboxylate U473_RS02000 Cd RS01885 Cd cyclohydrolase/ glutamine-- -D-fructose 1,6- -D-glucose diaminopimelate U473_RS13050 U473_RS12175 U473_RS10255 U473_RS11885 L-aspartyl- reductoisomerase: bifunctional 4-hydroxy- gln 18-hydroxystearoyl- an [HPr protein]- an [amino group carrierU473_RS10645 protein]- methoxy-6-polyprenyl-1,4- U473_RS13710 1-[18-hydroxyoeoyl]-2-U473_RS06125 1-palmitoyl-U473_RS06125 [+ 2 isozymes] [+ 3 isozymes] reductase: [+ 3 isozymes] glycine glycine phosphoribosyl- 2-oxobutanoate L-aspartyl- tRNA ligase: bisphosphate 6-phosphate AMP diphosphate IMP a holo-[EntF (2E,7Z)- a (3R)-3- a cis-delta11-3- D-ribulose RS07835 4-phosphate U473_RS08380 ornithine tetrahydrodipicolinate met 3-oxoacyl-[acyl- succinate acetyl-CoA alpha,alpha- CoA N π -phospho- pyruvate C-terminal-γ-(5-phospho- benzoquinol methylase: [18-hydroxy-lioleoyl]-sn 2-myristoyl KDGP U473_RS09170 betaine betaine lipid A RS08230 lipid A ATP 4-phosphate U473_RS12245 an L-glutaminyl- 3',5'-ADP L-seryl-carrier tetradecenoyl-CoA hydroxyglutaryl- trans-4-hydroxy- hydroxyC30:1- 5-phosphate (2R)-2,3- acetolactate gln acetyltransferase/ synthase: carrier-protein] phosphotrehalase: L-histidine L-glutamyl)-L-glutamate U473_RS06040 -glycerol 3-phosphate phosphatidate diphosphatase: Gln protein] [acp] methyl ester L-proline [acp] aspartate- dihydroxy-3- N-acetylglutamate U473_RS04920 reductase: [tRNA ] glycine glycine tetrathionate A synthase aspartate- Gln U473_RS12250 menaquinol-11 U473_RS10410 semialdehyde methylbutanoate synthase: (2S,4S)-4- a tRNA RS06475 RS09910 small subunit: carbamoyl semialdehyde U473_RS06360 glyoxylate betaine betaine 1-(5-phospho-β- dehydrogenase: U473_RS10640 hydroxy-2,3,4,5- malate C1 Compound Utilization and Assimilation 2,3-dihydroxy- U473_RS08385 phosphate N-acetyl-L- dehydrogenase: β-ketododecanoyl- thiosulfate A(H2) D-ribosyl)-AMP U473_RS04910 isovalerate ornithine tetrahydrodipicolinate isocitrate lyase: synthase A: glucokinase: RS04665 synthase U473_RS04910 [acp] synthase: 1915 (5Z)- a (9Z)-3- a (9Z)-3- acetolactate 4-hydroxy- L-selenocysteine biosynthesis I (bacteria) U473_RS05580 U473_RS05585 D-glucopyranose U473_RS10385 (15Z)- 18-hydroxyoleate pristanate a pseudouridine DMKH2-13 [EntB aryl- a [protein] C-terminal a O- an insertion sequence a 3-oxoicosanoyl- a D-hexose predicted bifunctional L-aspartate- dehydratase: large subunit: U473_RS06350 formate assimilation into 5,10- D-glucopyranose coenzyme A tetradecenoyl-CoA oxohexadec- oxooctacos- synthase, tetrahydrodipicolinate L-aspartate- reductive 6-phosphate tetracosenoate in 23S rRNA carrier protein] S-farnesyl-L-cysteine sialoglycoprotein element IS30 [acp] ABC phosphoribosyl- semialdehyde U473_RS08395 U473_RS06630 a 3- methylenetetrahydrofolate long-chain fatty long-chain fatty long-chain fatty 23S rRNA bifunctional isoprenylcysteine acyl-CoA 3-oxoacyl-ACP 9-enoyl-[acp]3-oxoacyl-ACP 9-enoyl-[acp]3-oxoacyl-ACP Peptide Peptide large subunit, reductase: semialdehyde Glu monocarboxylic acid cycle holo-[acyl- O-sialoglycoprotein transposase: glucokinase: transporter 3-methyl-2- sec oxododecanoyl- acid--CoA ligase: acid--CoA ligase: acid--CoA ligase: (pseudouridine(1915)- carboxyl dehydrogenase: AMP homoserine biosynthetic type: [+ 2 isozymes] ser a tRNA demethylmenaquinone carrier-protein] U473_RS05600 reductase: reductase: reductase: U473_RS10385 of a peptide RS09060 oxobutanoate U473_RS05945 homoserine selenide [acp] formate U473_RS08110 U473_RS08110 U473_RS08110 N(3))-methyltransferase methyltransferase: endopeptidase: U473_RS08050 cyclohydrolase/ dehydrogenase: U473_RS08390 carbamoyl an L-glutamyl- D-threo-isocitrate (S)-malate acetyl-CoA methyltransferase/2- synthase: [+ 6 isozymes] U473_RS02000 U473_RS02000 U473_RS02000 L-ornithine (S)-2,3,4,5- dehydrogenase: 3-oxoacyl-ACP Glu formate-- RlmH: U473_RS12415 U473_RS09030 U473_RS04085 an insertion Peptide RS10755 Peptide phosphoribosyl- U473_RS02770 (S)-2-aceto-2- phosphate L-tryptophan biosynthesis selenide, water serine-- [tRNA ] (Z)-15- 18-hydroxyoleoyl- an N 3 - methoxy-6-polyprenyl-1,4- U473_RS13710 a [protein] C-terminal [+ 2 isozymes] a (3R)-3-[+ 3 isozymes] a (3R,9Z)-3-[+ 3 isozymes] a cis-delta9-3-[+ 3 isozymes] D-hexose 6- 2-isopropylmalate tetrahydrodipicolinate U473_RS02770 reductase: a tRNA glu tetrahydrofolate AMP diphosphate AMP diphosphate AMP diphosphate pristanoyl-CoA (2E,5Z)- ATP branched-chain- tRNA ligase: aconitate malate tetracosenoyl-CoA CoA 1915 benzoquinol methylase: a holo-[EntB aryl- sequence IS30 with phosphate hydroxybutanoate dikinase SelD: ligase: methylpseudouridine 3',5'-ADP S-farnesyl-L- a peptide tetradecenoyl-CoA hydroxyicosanoyl- hydroxyhexadec- hydroxyC28:1- diphosphatase: L-homoserine synthase: amino-acid LL-diaminopimelate U473_RS12705 U473_RS02000 hydratase 1: dehydrogenase: formate C- pyruvate U473_RS06040 carrier protein] integrated transposon ketol-acid chorismate L-homoserine U473_RS03785 U473_RS13060 in 23S rRNA cysteine methyl ester [acp] 9-enoyl-[acp] [acp] predicted RS07820 U473_RS10410 U473_RS08375 transaminase: aminotransferase: [+ 3 isozymes] U473_RS10205 U473_RS01340 10 acetyltransferase: synthase: reductoisomerase: an L-seryl- an N - menaquinol-13 ABC 1-(5-phospho-β-D-ribosyl)- homoserine U473_RS02785 U473_RS05435 a (3R)-3- U473_RS01170 U473_RS04530 Peptide Peptide anthranilate homoserine selenophosphate sec formyltetrahydrofolate transporter kinase: (2S)-2- U473_RS08380 [tRNA ] hydroxydodecanoyl- 5-[(5-phosphoribosylamino) synthase: L,L- kinase: isoleucine-- cis-aconitate oxaloacetate bifunctional of a peptide methylideneamino]imidazole- U473_RS02780 isopropylmalate (R)-2,3-dihydroxy- ornithine [acp] ile carbamoyltransferase: U473_RS08145 diaminopimelate U473_RS02780 tRNA ligase: aconitate methylenetetrahydrofolate Alcohol Degradation 2-amino-6-[1-hydroxyethyl]- a very-long- all-trans- N-acetyl-D- a (7Z)-3- RS11780 4-carboxamide O-phospho- 3-isopropylmalate val 3-methylpentanoate L-seryl-tRNA(Sec) 3-hydroxyacyl- U473_RS06730 pyruvate decaprenyl 2-carboxy-1,4- galactosamine DMK-12 3'-dephospho- a RNA-DNA hybrid NMN D-threo-isocitrate oleoyl-CoA oxohexacos- a DNA segment pyruvate predicted U473_RS10615 anthranilate diaminopimelate O-phospho- [acyl-carrier- an L-isoleucyl- hydratase 1: dehydrogenase/ 7-methyl-7,8-dihydropterin chain fatty acid naphthoquinol ATP biotin ATP ABC 1-(5-phosphoribosyl)-5- L-homoserine 2,3-dihydroxy-3- selenium Ile recombinase dehydratase [tRNA ] U473_RS10205citrate synthase: methenyltetrahydrofolate glycerol and glycerophosphodiester degradation 2-amino-4-hydroxy-6- long-chain fatty diphosphate 1,4-dihydroxy- 6-phosphateN-acetylglucosamine- bifunctional CoA ribonuclease HII: bifunctional NADP-dependent acyl-CoA 7-enoyl-[acp]3-oxoacyl-ACP pyruvate Peptide Peptide methylvalerate epimerase: L-homoserine transferase: protein] Ile dephospho- transporter [(5- phosphoribosylamino) threonine small subunit: anthranilate a tRNA cyclohydrolase: hydroxymethyldihydropteridine acid--CoA ligase: demethylmenaquinone U473_RS06275 metallophosphatase/ isocitrate dehydrogenase: biotin--[acetyl- reductase: RecA: carboxylase: hydro-lyase: U473_RS06565 U473_RS03730 dehydratase U473_RS01330 2-naphthoate 6-phosphate CoA kinase: of a peptide methylideneamino]imidazole- synthase: U473_RS08365 phosphoribosyltransferase: threonine acetyl-CoA U473_RS04090 diphosphokinase: U473_RS13085 U473_RS08110 methyltransferase/2- ribonuclease HI: 5'-nucleotidase: dehydrogenase: U473_RS08050 CoA-carboxylase] U473_RS02000 U473_RS05030 U473_RS09960 U473_RS08395 FabZ: a glycerophosphodiester polyprenyltransferase: deacetylase: U473_RS01415 biotin RS00750 biotin RS06265 4- carboxamide isomerase: U473_RS02775 3-isopropylmalate U473_RS08140 meso- synthase: citrate [1-(2-amino-7-methyl-4-oxo- methoxy-6-polyprenyl-1,4- U473_RS01070 U473_RS02020 U473_RS01335 [+ 2 isozymes] ligase: [+ 2 isozymes] an L- U473_RS11665 a 5,10- a very-long-chain U473_RS09820 U473_RS09710 + 1-(β-D a (3R,7Z)-3-[+ 3 isozymes] a DNA segment U473_RS10420 (S)-3-methyl-2- diaminopimelate U473_RS02775 glycerol 7,8-dihydro-3H-pteridin- AMP diphosphate D-galactosamine benzoquinol methylase: ADP coenzyme A H a nucleoside 5'- (2E,9Z)- U473_RS05930 oxaloacetate dehydratase N-(5-phosphoribosyl) selenocysteinyl- methenyltetrahydrofolate fatty acyl-CoA DMKH2-10 acetate DNA ribofuranosyl) 2-oxoglutarate biotinyl-5'- hydroxyhexacos- in reverse thr oxopentanoate a (2E)-dodec- 6-yl)]ethyl diphosphate 6-phosphate U473_RS06040 monophosphate octadecenoyl-CoA phosphoribulosylformimino- large subunit: L-citrulline -anthranilate sec leucine-- glycerophosphodiester nicotinamide adenylate orientation thr [tRNA ] 2-enoyl-[acp] leu bifunctional 7-enoyl-[acp] AICAR-phosphate U473_RS08370 branched-chain- tRNA ligase: glycerol kinase: phosphodiesterase: menaquinol-12 RS08710 RS03850 amino-acid phosphoribosylanthranilate methylenetetrahydrofolate argininosuccinate dodecanoyl-[acyl- U473_RS03240 an L-leucyl- pyruvate fermentation Fermentation U473_RS08495 U473_RS08535 2-isopropylmaleate transaminase: isomerase: U473_RS08130 dehydrogenase/ imidazole glycerol synthase: carrier-protein] Leu 1-(o- lys [tRNA ] to butanoate methenyltetrahydrofolate phosphate U473_RS02785 U473_RS10610 reductase: Leu Detoxification a (5Z)-3- (2Z)-2-aminobut- 3-isopropylmalate carboxyphenylamino) L-isoleucine L-cysteine a tRNA cyclohydrolase: Fatty Acid and sn-glycerol 3-phosphate a ring-opened 7-methylguanine in DNA a nucleoside a single ADP-D-ribose 3-oxo- a [protein] Ser/Thr a double- synthase L-arginino- U473_RS09955 pyruvate 7-hydroxylaurate phytenate linoleate a ribonucleic acid a uridine in tRNA enterobactin oxotetracos- precorrin-6B RS13510 2-enoate dehydratase -1'-deoxyribulose biosynthesis IV biosynthesis I U473_RS04090 Lipid Degradation triphosphate stranded DNA docosapentaenoyl-CoA helix DNA RS01680 subunit HisH: ile succinate pyruvate DNA-formamidopyrimidine long-chain fatty long-chain fatty long-chain fatty endonuclease IV: ADP-ribose 3-oxoacyl-[acyl- tRNA 5-enoyl-[acp] DNA helicase small subunit: 5'-phosphate a 5,10- sn-glycerol-3-phosphate reactive oxygen DNA-directed HPr kinase/ enterochelin 3-oxoacyl-ACP precorrin-6x superpathway of L-aspartate a dodecanoyl-[acp] synthase: β phenylmercury acetate degradation glycosylase: U473_RS05545 acid--CoA ligase: acid--CoA ligase: acid--CoA ligase: U473_RS05450 pyrophosphatase: carrier-protein] dihydrouridine RecQ: U473_RS10425 U473_RS08365 argininosuccinate ser fatty acid -oxidation I dehydrogenase subunit species degradation RNA polymerase phosphorylase: esterase: reductase: reductase: indole-3-glycerol propanoate and L-asparagine biosynthesis U473_RS04530 methylenetetrahydrofolate DNA-formamidopyrimidine U473_RS08110 U473_RS08110 U473_RS08110 endonuclease IV: U473_RS04325 reductase: synthase DusB: U473_RS05345 imidazole glycerol 3-isopropylmalate lyase: phosphate long-chain fatty serine O- valine-- C: U473_RS08480 subunit omega: U473_RS10515 U473_RS05515 U473_RS02000 U473_RS10100 val acetyl-CoA a (3Z)-alk-3- superoxide mercuriphenyl glycosylase: U473_RS01405 U473_RS06975 D-ribofuranose U473_RS06360 U473_RS13095 N-(2,3- [+ 2 isozymes] RS13860 phosphate 2-iminobutanoate dehydratase U473_RS10605 synthase: acid--CoA ligase: acetyltransferase: tRNA ligase: sn-glycerol-3-phosphate 2,6-diamino-4-hydroxy-5-(N 7-hydroxylauroyl- U473_RS06540 (5Z,8Z,11Z,14Z,17Z) a [protein] (L-serine/L- a 5,6-dihydrouridine a (3R,5Z)-3-[+ 3 isozymes] an unwound Glu 3-oxoacyl-[acyl- enoyl-CoA acetate an apurinic site within DNA AMP diphosphate diphosphate AMP phytenoyl-CoA AMP diphosphate linoleoyl-CoA a 5'-phosphooligonucleotide 5-phosphate AMP dihydroxybenzoyl) precorrin-6A synthase large subunit: argininosuccinate U473_RS08135 U473_RS08110 U473_RS13185 U473_RS02595 acetyl-CoA dehydrogenase subunit -methyl)formamidopyrimidine CoA [+ 4 isozymes] -3R-hydroxy- threonine) phosphate in tRNA hydroxytetracos- double- RS04110 L-proline carrier-protein] an L-valyl- superoxide dismutase: -L-serine subunit HisF: U473_RS08370 lyase: propanoyl-CoA O-acetyl-L-serine Val a ribonucleic acid docosapentaenoyl-CoA 5-enoyl-[acp] stranded DNA (1S,2R)-1-C-(indol-3- aspartate reductase: [tRNA ] acetyltransferase: A: U473_RS08490 U473_RS05360 U473_RS10415 biosynthesis I Val (2R,3S)-3- U473_RS11415 U473_RS06360 laurate a tRNA U473_RS08055 superoxide dismutase: yl)glycerol 3-phosphate 2-oxoacid aminotransferase: cysteine synthase DHAP RS07985 2-oxobutanoate isopropylmalate ferredoxin U473_RS05860 A: U473_RS10340 β-ketomeristoyl- long-chain fatty acetyl-CoA a (2E)-2- U473_RS00875 D-erythro- Glu arg tryptophan 2+ 967 1-deoxy-L- 3-isopropylmalate [acp] synthase: acetyltransferase: enoyl-CoA Hg benzene acetate α,ω-9Z- a peptide with a a cytosine (5Z)- an unfolded a [protein]- RS04620 AICAR imidazole-glycerol- glutamate synthase oxidoreductase: aspartate cysteine synthase acid--CoA ligase: a 7,8-dihydro-8-oxoguanine in DNA 2-methylbutanoate decanoate ARP glycero-tetrulose phosphoenol 2-deoxygluconate (R)-lactate acetolactate dehydrogenase: U473_RS06350 U473_RS08080 long-chain fatty hydrogen peroxide octadecenedioate leader sequence in 16S rRNA dGDP a protein dodecenoyl-CoA protein L-histidine phosphate 5-kinase: subunit alpha: U473_RS08305 aminotransferase: A: U473_RS02140 U473_RS08110 a 2,3,4-saturated enoyl-CoA mercury(II) DNA-formamidopyrimidine acetate-- long-chain fatty long-chain fatty 16S rRNA 4-phosphate pyruvate 2-deoxy-D- acyl-CoA histidine kinase: synthase U473_RS08360 alanine-- coenzyme A acid--CoA ligase: signal peptidase 6,7-dimethyl-8- GPR chaperonin GroL: D-2-hydroxyacid imidazoleglycerol- U473_RS09180 U473_RS08120 [+ 2 isozymes] U473_RS06560 ala acetoacetyl-CoA fatty acid acyl-CoA hydratase: a 2,3,4- reductase: glycosylase: U473_RS05545 CoA ligase: acid--CoA ligase: acid--CoA ligase: (cytosine(967)-C(5)) pyruvate kinase: gluconate 3- dehydrogenase: U473_RS14265 RS00165 small subunit: (2S)-2-isopropyl- γ-L-glutamyl lauroyl-CoA tRNA ligase: U473_RS08110 I: U473_RS06285 ribityllumazine endopeptidase: U473_RS13900 dehydrogenase: phosphate tryptophan cys a 3-oxotetradecanoyl- dehydrogenase:U473_RS08100 saturated (3R)-3- U473_RS13595 DNA-formamidopyrimidine U473_RS08270 U473_RS08110 U473_RS08110 -methyltransferase: U473_RS01310 dehydrogenase: U473_RS08050 histidine kinase: U473_RS08385 3-oxosuccinate 5-phosphate 2-oxobutanoate asp U473_RS03105 ω signal peptidase synthase: U473_RS03305 chaperonin: U473_RS00950 dehydratase: L-asparagine synthase [acp] an L-alanyl- (S)-3- U473_RS08050 a 2,3,4- hydroxyacyl-CoA glycosylase: U473_RS01405 -carboxy- U473_RS06515 U473_RS09830 [+ 2 isozymes] U473_RS10955 RS06500 superpathway of L-serine Ala a 2,3,4-saturated Hg 0 2-methylbutanoyl- I: U473_RS06290 967 U473_RS10150 a peptide a peptide U473_RS03335 a [protein]- U473_RS10430 acetolactate glutamate-5- biosynthesis III subunit beta: [tRNA ] hydroxybutanoyl- [+ 2 isozymes] saturated (3S)-3- AMP diphosphate diphosphate AMP decanoyl-CoA AMP diphosphate (9Z)-octadec- a 5-methylcytosine 6,7-dimethyl-8-(1- dGTP pyruvate 3-dehydro-2- (2E,5Z)- pyruvate and glycine biosynthesis I acetolactate 3-oxoacyl-ACP Ala O H O hydroxyl radical an apurinic site within DNA 7,8-dihydro-8-oxoguanine CoA N-phospho- synthase, semialdehyde a tRNA CoA fatty acyl CoA 2 2 9-enoyl-CoA a leader sequence a peptide in 16S rRNA deoxy-D-gluconate dodecenoyl-CoA a protein imidazole acetol- (tRNA-dependent) U473_RS08125 synthase reductase: hydroxyacyl-CoA D-ribityl)lumazine RS04005 large subunit, dehydrogenase: aspartate asparagine dehydrogeanse: L-histidine phosphate 4-methyl-2- 3-phospho- small subunit: U473_RS02000 biosynthetic type: U473_RS09175 asp ser ammonia- synthase U473_RS08075 oxopentanoate D-glyceratephosphoglycerate indole U473_RS08385 phosphatidylglycerol histidinol- U473_RS08390 lyase: aspA (glutamine- [+ 3 isozymes] (S)-3- RS04505 L-glutamate-5- dehydrogenase: a (3R)-3- biosynthesis II (non-plastidic) (2R)-phospho- a ribonucleoside 1-oleyl-2-lyso- cobalt- a (6Z)-3- phosphate branched-chain- acetolactate aspartate hydrolyzing): hydroxybutanoyl- 3-methyl-2-oxobutanoate α-linolenate F6P octanoate MEP CTP 4-guanidinobutyramide a nucleoside butan-1-ol (S)-2-aceto-2- semialdehyde U473_RS00770 hydroxytetradecanoyl- asparagine-- 3-sulfolactate 5'-monophosphate phosphoenol dADP phosphatidate precorrin-5B oxooctadec- RS02155 transaminase: amino-acid an L-aspartyl- tryptophan synthase, ammonia-lyase: U473_RS03565 asn CoA a 2,3,4-saturated 3-ketoacyl- a 2,3,4-saturated diphosphate hydroxybutanoate 3-phosphooxypyruvate [acp] DHAP tRNA ligase: 3-methyl-2-oxobutanoate long-chain fatty fructose-6- long-chain fatty 2-C-methyl-D- 2-phosphosulfolactate bifunctional pyruvate 1-acyl-sn-glycerol- cobalt-precorrin- 6-enoyl-[acp]3-oxoacyl-ACP nucleoside- butanol U473_RS06005 transaminase: Asn synthase large subunit, U473_RS02670 enoyl-CoA fatty acyl CoA CoA thiolase: 3-oxoacyl-CoA amidase: ketol-acid [tRNA ] glycerol-3- U473_RS05855 an L-asparaginyl- dehydrogenase subunit acid--CoA ligase: phosphate acid--CoA ligase: erythritol 4-phosphate phosphatase: metallophosphatase/ pyruvate kinase: 3-phosphate 5B (C(1))- reductase: diphosphate dehydrogenase: U473_RS02785 subunit beta: biosynthetic type: 3-hydroxyacyl- hydratase: U473_RS08055 U473_RS05310 acetate acetate L-histidinol- reductoisomerase: 3-phosphoserine aspartyl/glutamyl- phosphate [tRNA Asn ] VorB: U473_RS04200 U473_RS08110 aldolase: U473_RS08110 cytidylyltransferase: U473_RS04000 5'-nucleotidase: U473_RS01310 acyltransferase: methyltransferase: U473_RS02000 kinase: U473_RS13795 U473_RS08125 U473_RS08390 asn [acyl-carrier- U473_RS08100 RS12535 phosphate U473_RS08380 aminotransferase: dehydrogenase: tRNA Asn [+ 2 isozymes] U473_RS11960 U473_RS13170 U473_RS06125 U473_RS10090 U473_RS06030 RS12355 leu (S)-1-pyrroline- tRNA(Asn/Gln) fumarate protein] α 4-(cytidine 5'- U473_RS02020 dATP pyruvate a (3R,6Z)-3-[+ 3 isozymes] U473_RS00765 (S)-2-aceto-2- L-glutamate U473_RS06085 NADH CO isobutanoyl-CoA AMP diphosphate -linolenoyl-CoA D-glyceraldehyde diphosphate AMP octanoyl-CoA (2R)-3-sulfolactate 4-guanidinobutanoate dioleoyl cobalt- a nucleoside butan-1-al a cation a cation histidinol- (R)-2,3-dihydroxy- 5-carboxylate amidotransferase dehydratase crotonyl-CoA 2 dihydroxyacetone diphospho)-2-C- a ribonucleoside hydroxybutanoate biosynthesis III sn-glycerol 3-phosphate phosphatidate precorrin-6A hydroxyoctadec- triphosphate RS11585 phosphatase: 3-methylpentanoate pyrroline-5- 3-phospho- subunit C: trp FabZ: Amine and Polyamine methyl-D-erythritol 3-phosphate acetyl-CoA Carboxylate Degradation 6-enoyl-[acp] U473_RS10405 2,3-dihydroxy-3- carboxylate L-serine U473_RS00205 U473_RS11665 acyl-CoA Degradation 2-oxoglutarate dehydrogenase: RS07340 histidinol- methylvalerate reductase: an L-asparaginyl- L-glutamate glutamate a (2E)-tetradec- aspartate-- asp U473_RS08070 N-acetylglucosamine pyruvate decarboxylation to acetyl CoA an N 10 - all-trans- D-sedoheptulose D-glyceraldehyde D-erythrose D-xylulose adenosyl- an (11Z)-3- a [protein]- phosphatase: hydro-lyase: U473_RS09170 [tRNA Asn ] biosynthesis II (R)-2,3-dihydroxy- glycine tRNA ligase: D-galactonate degradation 2-carboxy-1,4- canavaninosuccinate 1-myristoylglycerol dehydrogenase: 2-enoyl-[acp] degradation I acetate AICAR dodecaprenyl oleate porphobilinogen a protein cobyrinate hydrogenobyrinate oxooctadec- acetamide U473_RS00780 U473_RS08395 superpathway of L- 3-methylpentanoate biosynthesis III a 1-acyl-sn U473_RS03030 [+ 2 isozymes] formyltetrahydrofolate naphthoquinol 7-phosphate 3-phosphate 4-phosphate 5-phosphate 3-phosphate L-arginine RS08810 asparagine biosynthesis aminoacyl-tRNA U473_RS06170 myristoyl-[acyl- an L-aspartyl- a [pyruvate dehydrogenase conversion bifunctional diphosphate transketolase: argininosuccinate long-chain fatty hydroxymethylbilane transketolase: 1-acyl-sn-glycerol- endopeptidase a,c-diamide cobyrinic acid 11-enoyl-[acp]3-oxoacyl-ACP protein pro L-alanine 2-oxoglutarate -glycerol 3- asp N-acetyl-D- 1,4-dihydroxy- cobyric acid histidinol (S)-3-methyl-2- ser hydrolase: glutamate 2,3-dihydroxy-3- Glu carrier-protein] [tRNA ] butanoyl-CoA E2 protein] N 6 -lipoyl-L-lysinepyruvate D-galactonate to acetyl-CoA phosphoribosylaminoimidazolecarboxamide U473_RS10710 lyase: U473_RS10605 acid--CoA ligase: synthase: U473_RS10710 3-phosphate La: a,c-diamide reductase: arginine kinase: amidase: RS05880 oxopentanoate biosynthesis III methylvalerate glyoxylate phosphate tRNA asp glucosamine dehydrogenase galactonate 2-naphthoate synthase CobQ: U473_RS05310 U473_RS12930 dehydrogenase: reductase: acetate formyltransferase/IMP transketolase: argininosuccinate U473_RS08110 U473_RS02525 transketolase: acyltransferase: U473_RS02460 synthase: U473_RS02000 U473_RS13130 asp hydro-lyase: alanine--glyoxylate 1-acyl-sn-glycerol- phosphate 6-phosphateN-acetylglucosamine- (acetyl- dehydratase: polyprenyltransferase: U473_RS10025 histidinol branched-chain- serine U473_RS06170 U473_RS09955 acetate-- cyclohydrolase: U473_RS00065 U473_RS10715 lyase: U473_RS11415 U473_RS10715 U473_RS06125 U473_RS10065 [+ 3 isozymes] a [protein]- aminotransferase: 3-phosphate butyryltransferase: 6-phosphate dihydrolipoyl U473_RS09820 a peptide a peptide a (3R,11Z)-3- ω dehydrogenase: amino-acid hydroxymethyltransferase: asn cys U473_RS08395 transferring) pyruvate U473_RS10245 D-xylulose D-ribose 5- diphosphate AMP oleoyl-CoA preuroporphyrinogen D-glyceraldehyde dimyristoyl adenosylcobyrate hydrogenobyrinate N -phospho- acetate Glu U473_RS12140 acyltransferase: U473_RS04175 deacetylase: dehydrogenase: 2-dehydro-3-deoxy- CoA ligase: FAICAR a tetrahydrofolate DMK-12 fumarate L-canavanine F6P hydroxyoctadec- RS00905 U473_RS10435 transaminase: U473_RS11875 cysteine (S)-3-methyl-2- a myristoyl-[acp] E1 component 5-phosphate phosphate 3-phosphate phosphatidate a,c-diamide L-arginine asparagine asparagine U473_RS06125 U473_RS09710 U473_RS08650 D-galactonate U473_RS08270 11-enoyl-[acp] RS05800 U473_RS02785 desulfurase: oxopentanoate gly a 1,2-diacyl- tyrosine-- butanoyl D-glucosamine subunit alpha: histidinal synthase synthase tyr [+ 2 isozymes] 2-dehydro-3- acetyl-CoA gly U473_RS09535 3-oxoacyl-[acyl- sn-glycerol tRNA ligase: phosphate 6-phosphate U473_RS02350 (glutamine- (glutamine- branched-chain- deoxygalactonokinase: ile [+ 2 isozymes] carrier-protein] 3-phosphate U473_RS08170 all-trans- histidinol hydrolyzing): hydrolyzing): amino-acid an L-tyrosyl- butyrate kinase: U473_RS10255 a 1-phosphatidyl- a dihydroceramide 2-carboxy-1,4- a 5-L-glutamyl- a nucleoside uroporphyrinogen-III NaMN formate 3-[(7'-methylthio) precorrin-3B pyridoxal 2-keto-D- acrylamide ala reductase: Tyr undecaprenyl an amino acid repressor LexA RS10240 dehydrogenase: U473_RS03565 U473_RS03565 transaminase: phosphatidate [tRNA ] U473_RS04185 a [pyruvate dehydrogenase a [pyruvate dehydrogenase 2-dehydro-3-deoxy- 1D-myo-inositol naphthoquinol ATP cobinamide [peptide] triphosphate heptyl]malate gluconate RS03475 U473_RS06360 Tyr D-gluconate inositol diphosphate bifunctional formate 3-oxoacyl-[acyl- 2,5-diketo-D- U473_RS10435 U473_RS02785 cytidylyltransferase: a tRNA α 6 6 1,4-dihydroxy- gamma- uroporphyrinogen-III 3-isopropylmalate precorrin-3B C(17)- butyrate kinase: -D-glucosamine urea degradation I E2 protein] N - E2 protein] N -S- D-galactonate degradation ATP:cob(I)alamin NTP amidase: β-ketopalmityl- U473_RS04795 phosphorylceramide 2-naphthoate glutamyltransferase: C-methyltransferase: metallophosphatase/ dehydrogenase- dehydrogenase: methyltransferase: carrier-protein] repressor LexA: gluconic acid U473_RS13995 6-phosphate dihydrolipoyl-L-lysine acetyldihydrolipoyl-L-lysine 6-phosphate adenosyltransferase: pyrophosphohydrolase: U473_RS05310 his asn asn ile [acp] synthase: a CDP- synthase: polyprenyltransferase: αU473_RS05630 U473_RS02530 5'-nucleotidase: N subunit alpha: U473_RS08360 U473_RS10110 reductase: U473_RS05165 reductase: glucosamine- D-gluconate U473_RS00955 an -(5-L- U473_RS03370 U473_RS06350 diacylglycerol butanoate urea U473_RS02955 U473_RS09820 U473_RS02020 U473_RS12125 10-(methylthio)- U473_RS06360 U473_RS13580 6-phosphate gluconokinase: a 1,2-diacyl- an inositol PPP adenosylcobinamide a peptide glutamyl)- a nucleoside 5'- precorrin-2 β-D- an electron- precorrin-4 cleaved 2,5-didehydro- acrylate RS09815 RS02190 i CO 4-pyridoxolactone D-glyceraldehyde DMKH2-11 amino acid 2 2-oxodecanoate a 3-oxohexadecanoyl- CDP-diacylglycerol-- Trp tryptophan-- deaminase: U473_RS09625 sn-glycerol phosphodihydroceramide monophosphate ribosylnicotinate transfer quinol D-gluconate a tRNA lipoate pyruvate D-gluconate repressor LexA [acp] glycerol-3-phosphate 3- tRNA ligase: U473_RS09705 3-phosphate urea-1-carboxylate acetyltransferase: 6-phosphate phosphatidyltransferase: U473_RS05480 an L-tryptophanyl- acetyl-CoA Carbohydrate Biosynthesis Cell Structure Biosynthesis Aromatic Compound Biosynthesis 3-oxoacyl-ACP glucosamine- U473_RS05500 U473_RS05015 Trp [tRNA ] 6-phosphate allophanate an all-trans- a (6S)-5- a uridine 38- 3-[(5'-methylthio) 3-oxo- RS00845 reductase: pyruvate fermentation to propanoate I a sulfurated 2-carboxy-1,4- a proteinogenic an N-modified an L-cysteinyl- wound RNA + RS12985 CDP-diacylglycerol-- trp hydrolase: SAM dethiobiotin polyisoprenyl glutathione L-phosphinothricin oxaloacetate cobyrinate NAD UDP-N-acetyl-D- UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) chorismate biosynthesis I U473_RS02000 deaminase: [sulfur carrier] naphthoquinol amino acid formyltetrahydrofolate aminoacyl-[tRNA] 40 in tRNA pentyl]malate [tRNA Cys ] icosatrienoyl-CoA glycogen biosynthesis I (from ADP-D-Glucose) 2,3-dihydroxybenzoate glycerol-3-phosphate 3- U473_RS11410 U473_RS02040 biotin diphosphate 1,4-dihydroxy- gamma- 5-formyltetrahydrofolate aminoacyl-tRNA phosphinothricin phosphoenolpyruvate tRNA 3-isopropylmalate aminoacyl-tRNA 3-oxoacyl-[acyl- RNA helicase: cobyrinic acid glucosamine biosynthesis I [+ 3 isozymes] oxaloacetate pseudouridine(38- carrier-protein] U473_RS05025 a,c-diamide NAD kinase: UDP-N-acetyl-α-D-glucosamine D-erythrose biosynthesis a (3R)-3- phosphatidyltransferase: synthase BioB: 2-naphthoate glutamyltransferase: cyclo-ligase: hydrolase: acetyltransferase: carboxykinase (ATP) dehydrogenase: hydrolase: D-glucopyranose F6P ammonium Amino Acid Degradation 40) synthase TruA: reductase: RNA helicase: synthase: U473_RS07255 RS01795 D-glucopyranose 4-phosphate hydroxyhexadecanoyl- U473_RS11670 malate U473_RS05290 polyprenyltransferase: U473_RS05630an α-(γ-L- U473_RS07445 U473_RS12930 U473_RS06600 : U473_RS10010 U473_RS08360 U473_RS12930 pro RS06715 pro 6-phosphate 6-phosphate UDP-N-acetylglucosamine chorismate 1-(3-sn- an unsulfurated an N-modified an uncharged U473_RS13460 Cys U473_RS06360 U473_RS12265 U473_RS10065 glucose-6- 3-deoxy-7- [acp] threonine-- dehydrogenase: met 5'-deoxyadenosine biotin U473_RS09820 L-cysteinyl-glycine glutamyl)-L- a 5,10- phosphoenol 38- 8-(methylthio)- a tRNA cys + 1-carboxyvinyltransferase: isochorismate thr [sulfur carrier] amino acid tRNA N-acetylphosphinothricin a pseudouridine 3R-hydroxy- cob(II)yrinate NADP phosphate phosphoglucomutase: phosphoheptulonate 3-hydroxyacyl- phosphatidyl) tRNA ligase: U473_RS01340 L-histidine degradation I DMKH amino acid methenyltetrahydrofolate pyruvate 2-oxooctanoate an unwound RNA U473_RS06815 synthase: methylmalonyl-CoA L-proline L-serine degradation 2 40 in tRNA icosatrienoyl-CoA a,c-diamide isomerase: U473_RS05720 synthase: [acyl-carrier- -sn-glycerol U473_RS01770 an L-threonyl- glycine cleavage his RS11230 his U473_RS08930 carboxyltransferase: degradation [+ 2 isozymes] protein] 3-phosphate Thr Aromatic Compound RS08630 U473_RS00760 α-D- U473_RS12095 isochorismate [tRNA ] (S)-methylmalonyl-CoAU473_RS04305 (S)-malate his dehydratase phosphatidylglycerophosphatase a tRNA Thr Degradation F6P glucopyranose UDP-N-acetyl-α-D-glucosamine-enolpyruvate 3-deoxy- fumarate hydratase: ser a [glycine-cleavage complex all-trans- sn-glycero-3- 2,5-dichloro-trans a uridine 516 3-[(4'-methylthio) a negatively phosphoenol A: U473_RS07140 pro glycine O-acetyl-L- 2-carboxy-1,4- glycerophosphoserine D-cellobiose trans-dienelactone DNA with lesion Fe 2+ D-arabino- FabZ: methylmalonyl- U473_RS01345 H protein] N 6 -lipoyl-L-lysine methanethiol tridecaprenyl propanoyl-CoA phosphate 1-phosphate UDP-N- isochorismatase: L-serine homoserine naphthoquinol phosphoethanolamine -dienelactone in 16S rRNA butyl]malate supercoiled DNA pyruvate RS08500 L-glutamine--D- U473_RS11665 phosphatidylglycerophosphatase protocatechuate proline dehydrogenase diphosphate glycerophosphodiester glycerophosphodiester cellobiose 16S rRNA excinuclease glucose-1-phosphate heptulosonate CoA epimerase: fumarate hydratase: ammonia-lyase, O-acetylhomoserine 1,4-dihydroxy- phosphate dienelactone 3-isopropylmalate DNA dienelactone fructose-6- acetylenolpyruvoylglucosamine U473_RS12345 A: U473_RS09235 degradation II (ortho- urocanate dehydrogenase: (aminomethyl- phosphodiesterase: phosphodiesterase: phosphorylase: ABC subunit A: pyruvate kinase: ferroxidase: RS12120 adenylyltransferase 7-phosphate a (2E)-hexadec- an L-1- U473_RS04300 U473_RS01350 iron-sulfur- aminocarboxypropyltransferase: acyltransferase: hydrolase: pseudouridine(516) dehydrogenase: topoisomerase I: hydrolase: phosphate reductase: U473_RS06820 (2S,3S)-2,3- cleavage pathway) U473_RS00175 transferring): 2-naphthoate U473_RS00600 U473_RS01310 U473_RS05670 3-dehydroquinate (S)-1-pyrroline- U473_RS08535 U473_RS08535 α U473_RS06375 synthase: U473_RS10560 aminotransferase: subunit GlgD: dihydroxy-2,3- 2-enoyl-[acp] phosphatidyl- serine-- urocanate dependent, U473_03940 U473_RS03255 polyprenyltransferase: sn-glycerol -D- U473_RS05500 U473_RS08360 U473_RS06205 U473_RS05500 synthase: ser (R)-methylmalonyl-CoA fumarate protocatechuate 5-carboxylate ethanolamine sn-glycerol propanoyl U473_RS08160 [+ 2 isozymes] U473_RS05565 dihydrobenzoate sn-glycerol tRNA ligase: hydratase: subunit beta: acetate met U473_RS09820 ser D-glucopyranose glucopyranose 7-(methylthio)-2- 3+ U473_RS13570 Glu ala UDP-N-acetyl-α-D-muramate U473_RS06010 palmitoyl-[acyl- glycine 3-phosphate 3-phosphate phosphate 2,5-dichloromaleylacetate a 16S rRNA a relaxed DNA 2-maleylacetate DNA without pyruvate Fe RS13825 U473_RS12705 an L-seryl- U473_RS11240 U473_RS06435 DMKH2-13 1-phosphate 516 oxoheptanoate D-glucosamine glucose-1-phosphate carrier-protein] methylmalonyl- 2-aminoprop- dihydrolipoyl dehydrogenase pseudouridine lesion RS11770 [tRNA ser ] 4-imidazolone- 6-phosphate adenylyltransferase: glutamate racemase: 3-dehydroquinate reductase: CoA mutase: 3-carboxy-cis 2-enoate dehydrogenase: (aminomethyl- U473_RS05570 UDP-N-acetylmuramate- a tRNA ser 5-propanoate phosphoglucosamine U473_RS02415 2,3- U473_RS09955 U473_RS04295 ,cis-muconate L-glutamate-5- U473_RS08650 transferring): a (1->4)- -L-alanine ligase: type II 3- a [glycine-cleavage a single- an N-formyl-L- salicin 6- D-gluconate 3-[(3'-methylthio) (2S)- an organic uridine dihydroxybenzoate imidazolonepropionase: semialdehyde a [glycine-cleavage[+ 2 isozymes] U473_03945 adenine 2503 in 23S rRNA glycerophosphoglycerol (S)-4-amino-5- acetate mutase: U473_RS13565 ADP-α-D-glucose U473_RS02605 dehydroquinate complex H protein] N 6 - methionylaminoacyl- a tRNA glu 5-aminolevulinate α-D-glucan a palmitoyl-[acp] succinyl-CoA succinate U473_RS11235 complex H protein] N 6 4'-phosphopantetheine ATP stranded RNA phosphate 6-phosphate propyl]malate ethylmalonyl-CoA hydroperoxide RS13110 RS06795 D-glt 23S rRNA (adenine(2503) polyribonucleotide glycerophosphodiester 6-phospho-beta- oxopentanoate 6-phosphogluconate D-glucosamine α dehydratase: L-glutamate aminomethyldihydrolipoyl- tRNA peptide glutamyl-tRNA 3-isopropylmalate porphobilinogen methylmalonyl- peroxiredoxin: uridine kinase: starch synthase: UDP-N-acetyl- -D-muramoyl-L-alanine 2-iminopropanoate -dihydrolipoyl-L-lysine -C(2))-methyltransferase nucleotidyltransferase: phosphodiesterase: glucosidase: acetate kinase: 1-phosphate U473_RS03985 proline-- (2-carboxy- N-formimino- gamma- L-lysine pantetheine-phosphate deformylase: reductase: dehydrogenase dehydrogenase: synthase: CoA epimerase: U473_RS05840 U473_RS03150 U473_RS05560 pro RlmN: U473_RS06510 U473_RS04870 U473_RS08535 U473_RS00510 U473_RS05865 UDP-N- PRPP biosynthesis I tRNA ligase: 2,5-dihydro- L-glutamate semialdehyde adenylyltransferase: U473_RS06525 U473_RS02510 (decarboxylating) U473_RS08360 U473_RS02535 U473_RS04300 [+ 4 isozymes] UDP-N-acetylmuramoyl- 3-dehydroshikimate a nucleoside a single- sn-glycerol a L-methionylaminoacyl- β-D-glucose an L-glutamyl- UMP acetylglucosamine a (1->4)- 5-oxofuran- dehydrogenase: 2503 U473_RS06415 glycerol salicyl alcohol : U473_RS09615 L-alanine--D-glutamate U473_RS08330 an L-prolyl- a 2-methyladenine in 23S rRNA 5'-deoxyadenosine met formate Glu 6-(methylthio)- (2R)- RS08040 Glycolysis 2-yl)-acetate formimidoylglutamase: U473_RS00185 3'-dephospho-CoA diphosphate stranded RNA 3-phosphate tRNA 6-phosphate [tRNA ] D-ribulose porphobilinogen acetyl phosphate an alcohol RS00115 diphosphorylase/ α-D-glucan D-ribose 5- palmitate Pro 2-oxohexanoate ethylmalonyl-CoA ligase: U473_RS06835 shikimate [tRNA ] carboxymuconolactone U473_RS11245 5-phosphate Pro pyruvate L-threonine glucosamine-1- phosphateribose-phosphate dehydrogenase: a tRNA aminomethyltransferase: phosphate N- UDP-N- long-chain fatty glycolysis III (from glucose) decarboxylase: Glu degradation II α pyrophosphokinase: U473_RS03205 U473_RS03885 acetyltransferase: UDP- -D-glucuronate acetylmuramoylalanine- acid--CoA ligase: U473_RS08665 Glu arbutin-6- U473_RS12920 (4,5-dihydro- an N 10 - an L-methionyl- D-cellobiose a dipeptide with a 3-[(6'-methylthio) a monocarboxylic a [protein]-L- RS00855 U473_RS12915 a glycogen biosynthesis (from -D-glutamate ligase: U473_RS08110 D-glucopyranose thr DL-allothreonine glutathione hypoglycin A pyruvate phosphate 2-oxoglutarate D-ala precorrin-8x an aryl sulfate PRPP shikimate 5-oxofuran- L-glutamine formyltetrahydrofolate [initiator tRNA Met ] 6'-phosphate C-terminal L-proline hexyl]malate acid amide proline (ω = 180) RS04420 UDP-glucose) U473_RS09205 6-phospho-beta- pyruvate 6-phospho-beta- Xaa-Pro N-acetyl-α-D- palmitoyl-CoA phenylalanine- 2-yl)-acetate degradation I methionyl-tRNA serine gamma- D-amino-acid 3-isopropylmalate precorrin-8X peptidylprolyl α glucokinase: L-aspartate glucosidase: synthase: glucosidase: dipeptidase: amidase: sulfatase: glucosamine UDP- -D-glucose meso-diaminopimelate UDP-N-acetyl-α-D-muramoyl- -tRNA ligase L-glutamate formyltransferase: hydroxymethyltransferase: glutamyltransferase: transaminase: dehydrogenase: methylmutase: isomerase: UDP-glucose 6- U473_RS10385 degradation I U473_RS00510 U473_RS04530 U473_RS00510 U473_RS03990 U473_RS05310 U473_RS12215 1-phosphate L-alanyl-D-glutamate subunit alpha: degradation IX (via L-2-amino-3- an N-formyl- U473_RS06520 U473_RS11875 U473_RS05630 β U473_RS03905 U473_RS08360 U473_RS10095 U473_RS13695 RS04250 dehydrogenase: gln D-glucopyranose a reduced -D-glucose a proteinogenic UDP-N- α U473_RS01835 D-glucopyranose 4-aminobutanoate) oxobutanoate L-methionyl- a tetrahydrofolate gly acetaldehyde L-cysteinyl-glycine hypoglycin B D-glucopyranose CO acetyl-CoA hydroquinone pro pyruvate D-glt 9-(methylthio)- a [protein]-L- UDP- -D-galactose shikimate 3- Inorganic Nutrient carbamoyl asp 6-phosphate flavodoxin 2 6-phosphate amino acid a monocarboxylate hydrogenobyrinate a phenol α U473_RS07610 6-phosphate met 2-oxononanoate proline (ω = 0) RS07900 acetylglucosamine biosynthesis UDP- -D- UDP-N-acetylmuramoyl- phosphate phenylalanine- 3-oxoadipate Metabolism phosphate glycine C- [initiator tRNA ] glucuronate D-ala L-alanyl-D-glutamate-- glucose-6- aspartate Glu diphosphorylase/ 3-phosphoshikimate 1- -tRNA ligase synthase acetyltransferase: UDP-α-D-glucose 2, 6-diaminopimelate phe phosphate aminotransferase: glutamate RS11630 glucosamine-1- carboxyvinyltransferase: subunit beta: urea cycle large subunit: U473_RS07635 a 2,3,4-saturated peptidoglycan peptidoglycan ligase: U473_RS06850 isomerase: U473_RS05860 decarboxylase: a single 7,8- a [protein]- an organic a dipetide with an N- demethyl-L- 2-chloro-trans phosphate N- UDP-glucose D-alanine--D-alanine U473_RS06000 U473_RS01840 an L-phenylalanyl- U473_RS06630 isobutanoate CTP 1,2-diacyl-sn- tetrapeptide, tetrapeptide, 3-ethylmalate D-glycerate citrate propionamide U473_RS00760 aspartate U473_RS01290 gly stranded DNA dihydromonapterin L-cysteine hydroperoxide terminal L-aspartate phosphinothricin -dienelactone acetyltransferase: 4-epimerase: ligase: U473_RS04575 Mur ligase: U473_RS08960 5-enolpyruvoyl- Phe Chemoautotrophic exodeoxyribonuclease glycerol 3-phosphate dihydroneopterin glycan chain 1 glycan chain 2 peroxiredoxin: dipeptidase RS04740 [tRNA ] arg [+ 7 isozymes] aminotransferase: 4-aminobutanoate acetate--CoA ligase: phosphatidate L,D- phosphinothricin dienelactone 3-isopropylmalate D-glycerate aconitate U473_RS12915 U473_RS07640 Phe Energy Metabolism amidase: α shikimate 3- a tRNA Glu VII small subunit: U473_RS08270 aldolase: transpeptidase: U473_RS05840 PepV: D-alanyl-D-alanine UDP-N-acetyl- -D-muramoyl-L-alanyl- F6P U473_RS06560 cytidylyltransferase: acetyltransferase: hydrolase: dehydrogenase: dehydrogenase: hydratase 1: RS08760 UDP-N-acetyl- [+ 4 isozymes] phosphate U473_RS04100 U473_RS13080 U473_RS05695 [+ 3 isozymes] U473_RS08815 U473_RS05310 α UDP-α-D-galactose γ-D-glutamyl-meso-2,6-diaminopimelate hydrogen oxaloacetate U473_RS04795 peptidoglycan U473_RS06600 U473_RS05500 U473_RS08360 U473_RS09225 U473_RS10205 -D-glucosamine chorismate 6-phosphofructokinase: a single-stranded a ribonucleoside isobutanoyl-CoA AMP diphosphate a CDP-2,3,4-saturated- 6-(hydroxymethyl) glycolaldehyde an alcohol an intra- a proteinogenic oxidation L-alanine oligodeoxyribonucleotide 5'-monophosphate -7,8-dihydropterin D-ala DAP-DAP protein disulfide asp N-acetyldemethyl- D-alanyl-D-alanine-adding synthase: U473_RS01305 diacylglycerol amino acid 2-chloromaleylacetate 2-oxovalerate hydroxypyruvate D-threo-isocitrate propanoate I (aerobic) argininosuccinate degradation IV L-glutamate crosslink L-phosphinothricin RS04350 enzyme: U473_RS08960 U473_RS06015 methionine-- β-D-fructose 1,6- L-glutamate met H lyase: degradation I RS10140 tRNA ligase: 2 bisphosphate arginase: ammonium degradation X ala UDP-N-acetyl-α-D-muramoyl-L- chorismate an L-methionyl- Ni/Fe- U473_RS10605 RNase R degradation a [protein] N-terminal- 2-chloro-cis- U473_RS12865 U473_RS13515 lysine within isovalerate glutathione glycyl-glycine icosapentaenoate coenzyme A O-ureido-L- 2-hydroxyisobutyramide precorrin-2 D-glycerate cis-dienelactone methylglyoxal Metabolic Regulator alanyl-γ-D-glutamyl-meso-2,6- hydrogenase, b- argininosuccinate alanine Glu an octanoyl-[acp] substrate RNA asp [elongator fructose-1,6- carbamoyl gcv protein H formyl-L-methionine homoserine dienelactone Met Glu dehydrogenase: gamma- ribonuclease R: long-chain fatty peptide Biosynthesis diaminopimeloyl-D-alanyl-D-alanine elongator tRNA ] type cytochrome lyase: phosphate glutamate octanoyltransferase: acetate--CoA ligase: argininosuccinate dienelactone precorrin-2 C(20)- D-glycerate dienelactone RS03545 Met bisphosphate U473_RS04345 amidase: glyoxalase: tRNA subunit: L-arginino-U473_RS11415 synthase glutamate dehydrogenase: U473_RS08270 glutamyltransferase: U473_RS10190 acid--CoA ligase: deformylase: synthase: hydrolase: methyltransferase: dehydrogenase: hydrolase: RS10555 ppGpp biosynthesis aldolase, class II: L-ornithine dehydrogenase: pyruvate aU473_RS07580 [glycine-cleavage U473_RS05630 a nucleoside 5'- U473_RS08110 U473_RS06525 U473_RS05310 U473_RS05270 U473_RS10690 succinate large subunit: U473_RS06170 a diribonucleotide U473_RS10610 U473_RS05500 U473_RS10080 U473_RS09225 U473_RS05500 U473_RS11965 U473_RS06170 2-oxoglutarate acyl-carrier protein complex H protein] γ-L-glutamyl- monophosphate icosapentaenoyl- an N-terminal L- A(H2) U473_RS06630 isovaleryl-CoA AMP diphosphate L-cysteinyl-glycine formate canavaninosuccinate 2-hydroxy-2- Amine and Polyamine Biosynthesis Secondary Metabolite Biosynthesis 2-oxoglutarate N 6 -octanoyl-L-lysine glycylglycine CoA methionyl-[protein] 2-chloromaleylacetate precorrin-3A hydroxypyruvate 2-maleylacetate (R)-lactate pppGpp argininosuccinate [+ 2 isozymes] methylpropanoate lysine-- RS03285 RS06800 a tRNA Lys triose-phosphate synthase: spermidine biosynthesis I putrescine autoinducer AI-2 biosynthesis I tRNA ligase: isomerase: U473_RS10610 carbamoyl (p)ppGpp phosphate a DNA containing guanosine 3'- biosynthesis I U473_RS13105 an L-lysyl- U473_RS10305 5,10-methylene- 3-methyl-2- a proteinogenic 2+ (S)-2,3- (indol-3-yl) D-glyceraldehyde ornithine leukotriene-C4 nicotinate PRPP an apurinic/ a ribonucleic acid a tripeptide sirohydrochlorin Co H O diphosphate 2-deoxy-D-ribose DHAP synthetase: Lys DHAP tetrahydromethanopterin oxobutanoate 2 a protein dihydrodipicolinate acetamide diphosphate 5'- SAM [tRNA ] NADH repair 3-phosphate amino acid U473_RS03005 SAM carbamoyltransferase: 3-methyl-2-oxobutanoate gamma- nicotinate apyrimidinic site ribonuclease PH: peptidase T: sirohydrochlorin inorganic beta-aspartyl- dipicolinate methylglyoxal triphosphate 3'- arg lys endonuclease III: amidase: ribokinase: RS12875 adenosylmethionine glyceraldehyde- U473_RS10615 hydroxymethyltransferase: glutamyltransferase: phosphoribosyltransferase: U473_RS02425 U473_RS13640 cobaltochelatase: diphosphatase: peptidase: synthase synthase: RS02665 diphosphatase: NADH U473_RS00960 U473_RS05310 U473_RS09280 decarboxylase: 3-phosphate U473_RS10545 U473_RS05630 U473_RS03540 a 3'-terminal a 5'-phospho- a nucleoside a proteinogenic U473_RS10105 U473_RS04495 U473_RS00665 subunit B: U473_RS05940 U473_RS03005 α γ a ribonucleic acid a dipeptide cobalt- U473_RS05395 dehydrogenase: L-citrulline THMPT 2-dehydropantoate an -( -L-glutamyl) NaMN unsaturated sugar [DNA] diphosphate amino acid + 2-deoxy-D-ribose SAH leukotriene-D4 sirohydrochlorin phosphate H asp a protein U473_RS04905 S-adenosylmethionine agmatine U473_RS10315 -L-amino acid dipicolinate (indol-3-yl)acetate 5-phosphate methylglyoxal RS02105 decarboxylase histidine-- GTP ppGpp 5'-methylthioadenosine/ his RS04565 proenzyme: agmatinase: tRNA ligase: 13-DPG S-adenosylhomocysteine U473_RS01435 U473_RS12005 U473_RS03025 an L-histidyl- (R)-NADHX 5-amino-4- a (1->4)- methyl β-D-glucoside (2R,3S)-3- PRPP 2-succinylbenzoate coenzyme A maltoheptaose a single a ribonucleoside hydrogencarbonate H + glycerol O chloride maltose pyrazinamide nucleosidase: His KDGP α 2 nucleoside- putrescine dAdoMet [tRNA ] bifunctional imidazolecarboxyamide stranded DNA triphosphate -D-glucan 6-phosphate isopropylmalate U473_RS01980 His alpha-glucosidase: alpha- RS12780 diphosphate GDP putrescine a tRNA ADP-dependent adenine 2-dehydro-3- o-succinylbenzoate- DNA primase: carbonic 6-phospho-beta- 3-isopropylmalate glycerol chlorite alpha- spermidine synthase: phosphoribosyltransferase: -CoA ligase: U473_RS02560 glucosidase: anhydrase: glucosidase: dismutase: amidase: kinase: pyrophosphokinase: NAD(P)H-hydrate deoxyphosphogluconate U473_RS03500 dehydrogenase: dehydrogenase: glucosidase: RS01630 guanosine-3',5'- U473_RS12010 S-ribosyl-L-homocysteine 3-phospho-D-glycerate U473_RS03000 U473_RS08910 D-glucopyranose maltohexaose ssDNA/pppN(pN) U473_RS02560 U473_RS12085 U473_RS00510 U473_RS09100 U473_RS05310 U473_RS06030 U473_RS03005 dehydratase/ aldolase: U473_RS10250 a (1->4)- β U473_RS08360 gldA U473_RS02560 bis(diphosphate) D-glyceraldehyde 4-(2'-carboxyphenyl) hybrid -D-glucose NAD(P)H-hydrate AICAR pyruvate n -1 D-glucopyranose H O CO MeOH 4-methyl-2- chlorite pyrazine-2- 3'-diphosphatase: spermidine 3-phosphate -4-oxobutyryl-CoA α-D-glucan 2 2 6-phosphate dihydroxyacetone D-glucopyranose S-ribosylhomocysteine epimerase: RS02640 U473_RS03005 glycine-- oxopentanoate carboxylate lyase: U473_RS01975 gly U473_RS13715 tRNA ligase: (S)-NADHX RS01365 GDP AI-2 U473_RS12240 2-phospho-D-glycerate a glycyl-[tRNA Gly ] a 5S rRNA UTP 6,7-dimethyl-8-(1- ATP-dependent maltohexaose maltopentaose maltotriose butanoyl-CoA acetoacetate precorrin-2 Co 2+ H O acetyl-CoA L-canavanine β-D-allopyranose carbonic acid predicted CAIR asp 2 Gly phosphopyruvate precursor NTP D-ribityl)lumazine Mg 2+ Mg 2+ ABC a tRNA NADH-hydrate ribonuclease M5: alpha-glucosidase: alpha-glucosidase: alpha-glucosidase: coat protein F: sirohydrochlorin acetyl-CoA arginase: riboflavin D-ribose carbonic RS13655 hydratase: phosphoribosylaminoimidazolesuccinocarboxamide pyrophosphohydrolase: Co 2+ Co 2+ met transporter met dehydratase: U473_RS12880 U473_RS02560 U473_RS02560 U473_RS02560 U473_RS00695 cobaltochelatase: hydrolase: U473_RS13515 synthase: pyranase: anhydrase: U473_RS10295 synthase: U473_RS00030 U473_RS03370 of L- (2R,4S)-2-methyl-2,4- U473_RS13715 a double-stranded D-glucopyranose maltopentaose D-glucopyranose maltotetraose D-glucopyranose maltose U473_RS10105 U473_RS03590 U473_RS10160 U473_RS09275 U473_RS12085 SAICAR a mature 5S-rRNA acetoacetyl-CoA butanoate urea L-canaline methioninepredicted dihydroxydihydrofuran-3-one oligonucleotide UMP cobalt-precorrin-2 acetate riboflavin ARP CO H O Co 2+ RS13455 Co 2+ NADH phosphoenolpyruvate β-D-allofuranose 2 2 ABC met methionine-- met transporter met tRNA ligase: pyruvate kinase: predicted of L- U473_RS12865 an L-methionyl- U473_RS01310 (2R,4S)-2-methyl-2,3,3,4- ABC methionine [initiator tRNA Met ] Co 2+ Co 2+ RS06410 tetrahydroxytetrahydrofuran initiator tRNA Met pyruvate transporter of Co2+ Co 2+ RS10120 Co 2+ an amino D-fructose a C4- acid a dicarboxylate a dicarboxylate 1-phosphate a branched- a β- dicarboxylate putrescine putrescine α a C4- a C4- Ni 2+ an an a basic sn-glycerol D-glucose 6- a sugar 6- glycine betaine glycine betaine an amino an amino an amino an amino -D- a nucleotide molybdate chain glucoside 6- an aromatic ammonium chromate phosphate spermidine spermidine trehalose dicarboxylate dicarboxylate an oligopeptide oligopeptide oligopeptide amino acid 3-phosphate phosphate phosphate D-gluconate gly gly acid acid acid acid xylopyranose amino acid phosphate amino acid predicted predicted predicted ABC ABC PEP-driven transporter RS11810 RS01130 RS09395 RS03825 RS06450 RS00480 RS02480 RS11425 RS06400 RS04045 RS01670 RS08355 RS05990 RS06790 RS03980 RS09880 RS10200 RS10600 RS03435 RS08335 RS05455 RS03735 RS10480 RS05685 RS11710 RS08905 RS07325 RS01810 RS07930 RS08020 RS03340 RS08695 RS12255 RS00910 RS00520 RS13960 RS05835 RS10260 RS11595 RS01375 RS13625 RS10770 RS03560 RS09930 RS10520 RS11645 RS12185 RS09690 RS05730 RS07830 RS06470 RS11160 RS03100 RS00645 RS12195 RS00720 RS04040 RS04075 RS05785 RS07480 RS09330 transporter RS05180 RS09915 RS00580 RS11545 RS07735 RS12420 RS07190 RS02455 RS11805 RS01125 RS09940 RS03420 RS13040 RS05960 RS02950 RS10145 RS02565 RS02115 RS09855 RS07165 RS11745 RS14285 RS09035 RS07515 RS03835 RS00940 RS06120 RS04805 RS00145 RS13500 RS07435 RS14310 RS10910 transporter of a C4- of an of D-fructose dicarboxylate amino acid ammonium

α-D- a branched- 2+ putrescine putrescine D-fructose trehalose a β-glucoside a C4- a C4- a C4- Ni an an a basic sn-glycerol D-glucose a sugar D-gluconate glycine betaine glycine betaine an amino an amino an amino xylopyranose a nucleotide molybdate chain chromate phosphate spermidine spermidine an aromatic dicarboxylate dicarboxylate dicarboxylate an oligopeptide oligopeptide oligopeptide amino acid 3-phosphate gly gly acid a dicarboxylatean amino a dicarboxylatean amino acid acid amino acid amino acid acid acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.