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Eric Betzig - Wikipedia https://en.wikipedia.org/wiki/Eric_Betzig

Eric Betzig

Robert Eric Betzig (born January 13, 1960) is an American who Eric Betzig works as a Professor of and Professor Molecular and Cell biology at the University of California, Berkeley.[2][3][4] He is also a Senior Fellow at the Janelia Farm Research Campus in Ashburn, Virginia.[2][4][5]

Betzig has worked to develop the field of fluorescence microscopy and photoactivated localization microscopy. He was awarded the 2014 in Chemistry for "the development of super-resolved fluorescence microscopy"[6] along with and fellow Cornell alumnus William E. Moerner.[7]

Contents Early life and education Career Bell Laboratories Ann Arbor Machine Company Born Robert Eric Return to academia Betzig[1] References January 13, External links 1960 Ann Arbor, Michigan, U.S. Early life and education Alma mater California Institute of Betzig was born in Ann Arbor, Michigan in 1960, the son of Robert Technology Betzig, an engineer, and Helen Betzig. Aspiring to work in the aerospace Cornell industry, Betzig studied Physics at the California Institute of Technology University and graduated with a BS degree in 1983. He then went on to study at where he was advised by Aaron Lewis and Michael Known for Nanoscopy, Isaacson. There he obtained an MS degree and a PhD degree in Applied fluorescence and in 1985 and 1988, respectively. For his PhD he microscopy focused on developing high resolution optical microscopes that could see Awards Member of the [8][9][10] past the theoretical limit of .2 micrometers. National Academy of Career Sciences (2015) Nobel Prize in

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Bell Laboratories Chemistry (2014) After receiving his , Betzig was hired by AT&T Bell Laboratories in the Semiconductor Physics Research Department in 1989. Scientific career That year Betzig's colleague, William E. Moerner, developed the first Fields Applied physics that could see past the .2 micrometer limit, known as Institutions Howard Hughes the Abbe limit, but it could only function at temperatures near absolute Medical zero. Betzig was awarded the William L. McMillan Award in 1992. Institute Inspired by Moerner's research, he became the first person to image University of individual fluorescent molecules at room temperature while determining California, their positions to more than .2 micrometers in 1993. For this he received Berkeley the William O. Baker Award for Initiatives in Research which was at the Near-field time, the National Academy of Sciences Award for Initiatives in Scanning Research.[8] Optical Microscopy (htt Ann Arbor Machine Company ps://search.proq uest.com/docvi In 1994, Betzig became frustrated with the academic community and the ew/303699541 uncertainty of the corporate structure of Bell Laboratories causing him to /) (1988) leave both. He spent some years as a house husband before reentering the workforce.[11] At his father's wish, in 1996 he took up the position of vice Doctoral Aaron Lewis, president of research and development at Ann Arbor Machine Company, advisor Michael then owned by the Betzig family.[7] Here he developed Flexible Adaptive Isaacson Servohydraulic Technology (FAST) and after spending millions of dollars Influences William E. on development, sold a total of two devices which did not allow him to Moerner [8][9][11][12] achieve commercial success. Website hhmi.org /scientists/eric- Return to academia betzig (http://hh mi.org/scientist In 2002, Betzig then returned to the field of microscopy by founding a firm s/eric-betzig) known as New Millennium Research, in Okemos, Michigan. Inspired by the work of Mike Davidson and his fluorescent proteins, he developed photoactivated localization microscopy (PALM), a method of controlling fluorescent proteins using pulses of light to create images of a higher resolution than previously thought possible. In the living room of his old collaborator, Harald Hess, they developed the first optical microscope based on this technology. They built their first prototype in less than two months, gathering widespread attention. In October of that year, Janelia hired him, but his lab was still under construction at the time.[9]

In early 2006, he formally joined the Howard Hughes Medical Institute's Janelia Farm Research Campus as a group leader to work on developing super high-resolution fluorescence microscopy techniques. He used this technique to study the division of cells in human embryos.[7][13] In 2010, he was offered the Max Delbruck Prize, but he declined it allowing to receive the award. In 2014, Betzig was jointly awarded the along with Stefan Hell and William E. Moerner.[6][9][14]

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In the summer of 2017, Betzig joined the faculty of UC Berkeley with a joint appointment at Lawrence Berkeley National Laboratory.[15]

References

1. "Eighty-Ninth Annual Commencement – California Institute of Technology" (http://cal techcampuspubs.library.caltech.edu/2491/1 /June_10,_1983.pdf) (PDF). caltechcampuspubs.library.caltech.edu. California Institute of Technology. June 10, Dual color localization microscopy 1983. Retrieved October 11, 2014. SPDMphymod/super-resolution microscopy 2. "Eric Betzig | UC Berkeley Physics" (https:// with GFP & RFP fusion proteins physics.berkeley.edu/people/faculty/eric-bet zig). physics.berkeley.edu. Retrieved 2019-07-18. 3. "Eric Betzig | Research UC Berkeley" (http s://vcresearch.berkeley.edu/faculty/eric-betz ig). vcresearch.berkeley.edu. Retrieved 2019-07-18. 4. "Eric Betzig" (https://www.hhmi.org/scientis ts/eric-betzig). HHMI.org. Retrieved 2019-07-18. 5. "Eric Betzig, PhD" (http://www.hhmi.org/scie ntists/eric-betzig). hhmi.org. Howard Hughes Medical Institute. Retrieved 2014-10-08. 6. "The Nobel Prize in Chemistry 2014" (http s://www.nobelprize.org/nobel_prizes/chemis try/laureates/2014/press.html). Nobelprize.org. Nobel Media AB. 2014-10-08. Retrieved 2014-10-08. 7. "Eric Betzig Wins 2014 Nobel Prize in Chemistry" (http://www.hhmi.org/news/eric- betzig-wins-2014-nobel-prize-chemistry). HHMI News. hhmi.org. 2014-10-08. Retrieved 2014-10-08. 8. "Eric Betzig" (http://www.janelia.org/people/ scientist/eric-betzig). janelia.org. Janelia Farm Research Campus. Retrieved 2014-10-08.

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9. Feltman, Rachel (October 8, 2014). "Nobel chemistry laureate's twisting path to molecular microscope breakthrough" (https://www.washingtonpost.com/national/health-science/nobel-c hemistry-laureates-twisting-path-to-molecular-microscope-breakthrough/2014/10/08/f06d6a2 e-4e75-11e4-8c24-487e92bc997b_story.html). Washington Post. Retrieved 19 August 2015. 10. Betzig, Robert Eric (1988). Nondestructive optical imaging of surfaces with 500 angstrom resolution (https://search.proquest.com/docview/303699541/) (Ph.D.). Cornell University. OCLC 79223216 (https://www.worldcat.org/oclc/79223216) – via ProQuest. 11. Timmer, John (April 10, 2015). "Quitting + failures + a microscope in the living room = Nobel Prize" (https://arstechnica.com/science/2015/04/quitting-failures-a-microscope-in-the-living-ro om-nobel-prize/). ars technicia. Retrieved 19 August 2015. 12. Gewin, Virginia (2006). "Eric Betzig, group leader, Janelia Farm Research Campus, Howard Hughes Medical Institute, Leesburg, Virginia". Nature. 440 (7083): 578. doi:10.1038/nj7083-578a (https://doi.org/10.1038%2Fnj7083-578a). 13. Feltman, Rachel (October 8, 2014). "The Nobel Prize in chemistry goes to three men who revolutionized microscopy" (https://www.washingtonpost.com/news/speaking-of-science/wp/2 014/10/08/the-nobel-prize-in-chemistry-goes-to-three-men-who-revolutionized-microscopy/). Washington Post. Retrieved 19 August 2015. 14. "EricBetzig: and Nobel Prize" (http://www.starmus.com/dt_team/eric-betzig/). Starmus. Retrieved 19 August 2015. 15. Israel, Brett (27 September 2016). "Nobel Prize winner to join UC Berkeley faculty" (http://new s.berkeley.edu/2016/09/27/nobel-prize-winner-to-join-uc-berkeley-faculty/). Berkeley News. Retrieved 28 September 2016.

External links

Eric Betzig talk: Developing PALM Microscopy (http://www.ibiology.org/ibiomagazine/issue-2/er ic-betzig-and-harald-hess-developing-palm-microscopy.html) Eric Betzig, SPIE Photonics West plenary presentation: Single molecules, cells, and super- resolution optics (http://spie.org/x112669.xml) Eric Betzig, Beyond the Nobel Prize -- New approaches to microscopy (http://spie.org/x11260 6.xml)

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