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Caso Relativamente Recente
Perché chiamiamo “fondamentale” la Cenerentola della ricerca? (di M. Brunori) Neanche nel Pnrr si trovano speranze di cambiamento e iniziative coraggiose per la ricerca di base. Ma nelle scienze della vita non sono rare le scoperte nate da progetti di ricerca curiosity driven che richiedono tempo per portare risultati Soci dell'Accademia dei Lincei. (a cura di Maurizio Brunori, Prof. emerito di Chimica e Biochimica, Sapienza Università di Roma, Presidente emerito della Classe di Scienze FMN dell’Accademia dei Lincei) Nelle scienze della vita non sono infrequenti le scoperte innovative nate da progetti di ricerca di base, iniziati per cercare di comprendere qualche importante proprietà di un essere vivente, misteriosa ma ovviamente necessaria se è stata conservata nel corso dell’evoluzione. Questi progetti sono quelli che si iniziano per curiosità intellettuale, ma richiedono libertà di iniziativa, impegno pluriennale e molto coraggio in quanto di difficile soluzione. Un successo straordinario noto a molti è quello ottenuto dieci anni fa da due straordinarie ricercatrici, Emmanuelle Charpentier e Jennifer Doudna; che a dicembre hanno ricevuto dal Re di Svezia il Premio Nobel per la Chimica con la seguente motivazione: “for the development of a new method for genome editing”. Nel 2018 in occasione di una conferenza magistrale che la Charpentier tenne presso l’Accademia Nazionale dei Lincei, avevo pubblicato sul Blog di HuffPost un pezzo per commentare l’importanza della scoperta di CRISPR/Cas9, un kit molecolare taglia-e-cuci che consente di modificare con precisione ed efficacia senza precedenti il genoma di qualsiasi essere vivente: batteri, piante, animali, compreso l’uomo. NOBEL PRIZE Nobel Chimica Non era mai accaduto che due donne vincessero insieme il Premio Nobel. -
The Scanning Transmission Electron Microscope EDITOR-IN-CHIEF PETER W
Advances in IMAGING AND ELECTRON PHYSICS VOLUME 159 Cold Field Emission and the Scanning Transmission Electron Microscope EDITOR-IN-CHIEF PETER W. HAWKES CEMES-CNRS Toulouse, France Advances in IMAGING AND ELECTRON PHYSICS VOLUME 159 Cold Field Emission and the Scanning Transmission Electron Microscope Edited by PETER W. HAWKES CEMES-CNRS, Toulouse, France AMSTERDAM • BOSTON • HEIDELBERG • LONDON NEW YORK • OXFORD • PARIS • SAN DIEGO SAN FRANCISCO • SINGAPORE • SYDNEY • TOKYO Academic Press is an imprint of Elsevier Academic Press is an imprint of Elsevier Radarweg 29, PO Box 211, 1000 AE Amsterdam, The Netherlands 32 Jamestown Road, London NW1 7BY, UK 30 Corporate Drive, Suite 400, Burlington, MA 01803, USA 525 B Street, Suite 1900, San Diego, CA 92101-4495, USA First edition 2009 Copyright # 2009, Elsevier Inc. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher. Permissions may be sought directly from Elsevier’s Science & Technology Rights Department in Oxford, UK: phone (+44) (0) 1865 843830; fax (+44) (0) 1865 853333; email: [email protected]. Alternatively you can submit your request online by visiting the Elsevier web site at http://www.elsevier.com/ locate/permissions, and selecting Obtaining permission to use Elsevier material. Notice No responsibility is assumed by the publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein. -
Aura Burnside
URBANWORKSREALESTATE.COM / 503.228.3080 FOR LEASE RESTAURANT / RETAIL / SERVICE AURA BURNSIDE 55 NE GRAND AVENUE, PORTLAND, OR 97232 NEW MIXED-USE DEVELOPMENT, LOCATED ON E. BURNSIDE BETWEEN GRAND AVE AND MLK JR. BLVD. TOTAL // 10,000 SF RANGE // 640 - 8,800 SF (DIVISIBLE) KIA HARTLEY / NICOLE ONDER / 503.228.3080 THE AURA // 1 AURA BURNSIDE ADDRESS // 55 NE GRAND AVENUE, PORTLAND, OR 97232 DELIVERY // Q2 2017 USES // RETAIL / SERVICE RETAIL / RESTAURANT RENTABLE TOTAL // 10,000 SF SF RANGE // 640 - 8,800 SF NEW CENTRAL EASTSIDE DEVELOPMENT The Aura is under development on E Burnside, between NE MLK Jr. Blvd. and NE Grand Ave in The Burnside Bridgehead, one of Portland’ most walkable and desirable neighborhoods. The mixed-use apartment and retail building features amenities that include landscaped rooftop fire pit and activity area with City and Mt Hood views, clubhouse with designer kitchen, bike lounge with lockers, grilling stations, plus on-site wine and bike storage facilities. GROUND FLOOR RETAIL SPACES Retail spaces front MLK Jr Blvd, E Burnside & NE Grand, all of which enjoy high traffic counts and strong walkability scores. Suites offer glass roll-up doors, 17 ft ceilings and space for outdoor seating. E. BURNSIDE & NE MLK BLVD THE AURA // 2 FLOOR PLAN << E.COUCH << SUITE #7 640 SF SUITE #6 683 SF LU# 14-169513 DZM Enlarged Plan - Ground Floor Arcade Section 4: >> NE GRAND AVE >> >> AVE >> NE GRAND << NE MLK JR BLVD << << JR BLVD << NE MLK Retail/ Retail/ Retail/ Commercial Commercial Commercial ne martinlutherboulevard king, jr. SUITE #1 SUITE #2 SUITE #3 SUITE #4 SUITE #5 3,800 SF 1,270 SF 1,270 SF 1,233 SF 1,227 SF ne grand avenue >> E.BURNSIDE STREET >> e burnside street arcade elevation BURNSIDE ELEVATION THE AURA // 3 AURA BURNSIDE E. -
Zhong Lin Wang, Ph.D. ([email protected])
Zhong Lin Wang, Ph.D. ([email protected]) http://www.nanoscience.gatech.edu Hightower Chair in Materials Science and Engineering and Regents' Professor at Georgia Tech, Atlanta, GA 30332, USA Dr. Zhong Lin (ZL) Wang is the Hightower Chair in Materials Science and Engineering and Regents' Professor at Georgia Tech, and Founding Director and Chief Scientist at Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences. Dr. Wang has made original and innovative contributions to the synthesis, discovery, characterization and understanding of fundamental physical properties of oxide nanobelts and nanowires, as well as applications of nanowires in energy sciences, electronics, optoelectronics and biological science. His discovery and breakthroughs in developing nanogenerators establish the principle and technological road map for harvesting mechanical energy from environment and biological systems for powering a personal electronics. His research on self-powered nanosystems has inspired the worldwide effort in academia and industry for studying energy for micro-nano- systems, which is now a distinct disciplinary in energy research and future sensor networks. He coined and pioneered the field of piezotronics and piezo-phototronics by introducing piezoelectric potential gated charge transport process in fabricating new electronic and optoelectronic devices. This breakthrough by redesign CMOS transistor has important applications in smart MEMS/NEMS, nanorobotics, human-electronics interface and sensors. Dr. Wang was elected as a foreign member of the Chinese Academy of Sciences in 2009, member of European Academy of Sciences in 2002, fellow of American Physical Society in 2005, fellow of AAAS in 2006, fellow of Materials Research Society in 2008, fellow of Microscopy Society of America in 2010, fellow of Royal Society of Chemistry, and fellow of the World Innovation Foundation in 2002. -
JACQUES DUBOCHET (75) Es Ist Derzeit Nicht Leicht, an Jacques Dubochet Heranzukom- Men
NoBelpreis TexT Mathias Plüss Bilder anoush abrar JACQUES DUBOCHET (75) Es ist derzeit nicht leicht, an Jacques Dubochet heranzukom- men. Ist man aber einmal bei ihm, so hat man ihn ganz für aus dem Waadtland ist ein Mensch wie du sich. Nicht nur lässt er sich keine Sekunde ablenken – er inte- und ich. Und gerade darum vielleicht ressiert sich auch für sein Gegenüber. Er pflegt Kolleginnen der ungewöhnlichste Nobelpreisträger, und Kollegen aus allen möglichen Disziplinen zu sich zum Essen einzuladen und mit Fragen zu löchern. Zu mir sagt er, den man sich vorstellen kann. als wir auf dem Weg zur Metro in Lausanne sind: «Und was Mit unserem Autor hat er eine kleine sind Sie für ein Mensch?» Zugfahrt gemacht. Dubochet ist 1942 in Aigle VD geboren. Er wuchs im Wal- lis und im Waadtland auf. In der Schule hatte er Mühe, konn- te aber dank verständnisvoller Lehrer die Matura machen. Er studierte Physik und wechselte dann zur Biologie. Die Statio- nen seiner Karriere waren Lausanne, Genf, Basel, Heidel- berg. Von 1987 bis 2007 war er Professor für Biophysik an der Universität Lausanne. Er ist mit einer Basler Künstlerin ver- heiratet und hat zwei erwachsene Kinder. Auch nach seiner Emeritierung engagiert er sich weiterhin: zum Beispiel im von ihm entwickelten Studienprogramm «Biologie und Ge- sellschaft», aber auch als Lokalpolitiker der SP an seinem Wohnort Morges VD. 4747 — — 20172017 DASDAS MAGAZIN MAGAZIN N° N° 20 «ICH VERSTEHE NICHTS VON CHEMIE» 4747 — — 20172017 DASDAS MAGAZIN MAGAZIN N° N° In der Schule Probleme, heute Nobelpreisträger: Jacques Dubochet aus Morges VD. Anfang Oktober gab das Stockholmer Nobelpreiskomitee be- … auch Luc Montagnier, der Entdecker des Aids-Vi- kannt, dass Jacques Dubochet den Chemie-Nobelpreis 2017 rus, entwickelte sehr bizarre Ideen. -
October 2017 Current Affairs
Unique IAS Academy – October 2017 Current Affairs 1. Which state to host the 36th edition of National Games of India in 2018? [A] Goa [B] Assam [C] Kerala [D] Jharkhand Correct 2. Which Indian entrepreneur has won the prestigious International Business Person of the Year award in London for innovative IT solutions? [A] Birendra Sasmal [B] Uday Lanje [C] Madhira Srinivasu [D] Ranjan Kumar 3. The United Nations‟ (UN) International Day of Non-Violence is observed on which date? [A] October 4 [B] October 1 [C] October 2 [D] October 3 4. Which country to host the 6th edition of World Government Summit (WGS)? 0422 4204182, 9884267599 1st Street, Gandhipuram Coimbatore Page 1 Unique IAS Academy – October 2017 Current Affairs [A] Israel [B] United States [C] India [D] UAE 5. Who of the following has/have won the Nobel Prize in Physiology or Medicine 2017? [A] Jeffrey C. Hall [B] Michael Rosbash [C] Michael W. Young [D] All of the above 6. Which state government has launched a state-wide campaign against child marriage and dowry on the occasion of Mahatma Gandhi‟s birth anniversary? [A] Odisha [B] Bihar [C] Uttar Pradesh [D] Rajasthan 7. The 8th Conference of Association of SAARC Speakers and Parliamentarians to be held in which country? [A] China [B] India [C] Sri Lanka [D] Nepal Correct 8. Which committee has drafted the 3rd National Wildlife Action Plan (NWAP) for 2017- 2031? [A] Krishna Murthy committee [B] JC Kala committee 0422 4204182, 9884267599 1st Street, Gandhipuram Coimbatore Page 2 Unique IAS Academy – October 2017 Current Affairs [C] Prabhakar Reddy committee [D] K C Patan committee 9. -
2005 Annual Report American Physical Society
1 2005 Annual Report American Physical Society APS 20052 APS OFFICERS 2006 APS OFFICERS PRESIDENT: PRESIDENT: Marvin L. Cohen John J. Hopfield University of California, Berkeley Princeton University PRESIDENT ELECT: PRESIDENT ELECT: John N. Bahcall Leo P. Kadanoff Institue for Advanced Study, Princeton University of Chicago VICE PRESIDENT: VICE PRESIDENT: John J. Hopfield Arthur Bienenstock Princeton University Stanford University PAST PRESIDENT: PAST PRESIDENT: Helen R. Quinn Marvin L. Cohen Stanford University, (SLAC) University of California, Berkeley EXECUTIVE OFFICER: EXECUTIVE OFFICER: Judy R. Franz Judy R. Franz University of Alabama, Huntsville University of Alabama, Huntsville TREASURER: TREASURER: Thomas McIlrath Thomas McIlrath University of Maryland (Emeritus) University of Maryland (Emeritus) EDITOR-IN-CHIEF: EDITOR-IN-CHIEF: Martin Blume Martin Blume Brookhaven National Laboratory (Emeritus) Brookhaven National Laboratory (Emeritus) PHOTO CREDITS: Cover (l-r): 1Diffraction patterns of a GaN quantum dot particle—UCLA; Spring-8/Riken, Japan; Stanford Synchrotron Radiation Lab, SLAC & UC Davis, Phys. Rev. Lett. 95 085503 (2005) 2TESLA 9-cell 1.3 GHz SRF cavities from ACCEL Corp. in Germany for ILC. (Courtesy Fermilab Visual Media Service 3G0 detector studying strange quarks in the proton—Jefferson Lab 4Sections of a resistive magnet (Florida-Bitter magnet) from NHMFL at Talahassee LETTER FROM THE PRESIDENT APS IN 2005 3 2005 was a very special year for the physics community and the American Physical Society. Declared the World Year of Physics by the United Nations, the year provided a unique opportunity for the international physics community to reach out to the general public while celebrating the centennial of Einstein’s “miraculous year.” The year started with an international Launching Conference in Paris, France that brought together more than 500 students from around the world to interact with leading physicists. -
Body-Integrated Self-Powered System for Wearable and Implantable
Article Cite This: ACS Nano XXXX, XXX, XXX−XXX www.acsnano.org Body-Integrated Self-Powered System for Wearable and Implantable Applications † ‡ ∇ † ‡ ∇ † ∇ † † § † § Bojing Shi, , , Zhuo Liu, , , Qiang Zheng, , Jianping Meng, Han Ouyang, , Yang Zou, , † § † § ⊗ † § ‡ ⊥ † § ∥ # Dongjie Jiang, , Xuecheng Qu, , Min Yu, Luming Zhao, , Yubo Fan,*, , Zhong Lin Wang,*, , , , † § ∥ and Zhou Li*, , , † CAS Center for Excellence in Nanoscience, Beijing Key Laboratory of Micro-nano Energy and Sensor, Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 100083, China ‡ Beijing Advanced Innovation Centre for Biomedical Engineering, Key Laboratory for Biomechanics and Mechanobiology of Chinese Education Ministry, School of Biological Science and Medical Engineering, Beihang University, Beijing 10083, China § College of Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing 100049, China ∥ Center on Nanoenergy Research, School of Physical Science and Technology, Guangxi University, Nanning 530004, China ⊥ National Research Center for Rehabilitation Technical Aids, Beijing 100176, China # School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States ⊗ School of Stomatology and Medicine, Foshan University, Foshan 528000, China *S Supporting Information ABSTRACT: The human body has an abundance of available energy from the mechanical movements of walking, jumping, and running. Many devices such as electro- magnetic, piezoelectric, and triboelectric -
RFP NUMBER 00000617 City of Portland, Oregon REQUEST FOR
RFP NUMBER 00000617 City of Portland, Oregon May 4, 2017 REQUEST FOR PROPOSALS FOR PORTLAND OPEN SPACE SEQUENCE RESTORATION PROJECT CONSTRUCTION MANAGER / GENERAL CONTRACTOR SERVICES PROPOSALS DUE: May 31, 2017 by 4:00 p.m. Response Envelope(s) shall be sealed and marked with RFP Number and Project Title. SUBMITTAL INFORMATION: Refer to PART II, SECTION B. PROPOSAL SUBMISSION Submit the Proposal to: Procurement Services City of Portland 1120 SW Fifth Avenue, Room 750 Portland, OR 97204 Attn: Celeste King Refer questions to: Celeste King City of Portland, Procurement Services Phone: (503) 823-4044 Fax : (503) 865-3455 Email: [email protected] A MANDATORY PRE-PROPOSAL MEETING has been scheduled for Thurs, May 18, 2017, at 1:30 pm starting at Ira Keller Fountain at SW Third & Clay Streets, Portland, OR 97204. TABLE OF CONTENTS . Notice to Proposers . General Instructions and Conditions of the RFP . Project Contacts . Part I: Solicitation Requirements Section A General Information Section B CM/GC Services Section C Exhibits Section D Proposal Forms . Part II: Proposal Preparation and Submittal Section A Pre-Proposal Meeting / Clarification Section B Proposal Submission Section C Proposal Content and Evaluation Criteria . Part III: Proposal Evaluation Section A Proposal Review and Selection Section B Contract Award . Exhibits Exhibit A CM/GC Disadvantaged, Minority, Women and Emerging Small Business Subcontractor and Supplier Plan Exhibit B Workforce Training and Hiring Program Exhibit C General Conditions of the Contract for CM/GC Projects Exhibit D Sample Pre-Construction Services Contract Exhibit E Sample Construction Contract Exhibit F Assignment of Anti Trust Rights Exhibit G CM/GC & Owner Team Roles and Responsibilities Table Exhibit H Design Team Contract Exhibit I Public Information Plan Exhibit J Project Validation Report for Lovejoy Fountain Rehabilitation Exhibit K Anticipated Project Schedule Exhibit L 30% Cost Estimate Exhibit M 30% Specification Table of Contents Exhibit N 30% Construction Drawings . -
Seunghyun Sim Bas Van Genabeek Takuzo Aida Bert Meijer
In association with NASA Takuzo Aida December 10, 2019 Seunghyun Sim Bas van Genabeek Bert Meijer Tokyo University Caltech SyMO-Chem Eindhoven University . cmeacs.org In association with NASA ACS GLOBAL OUTSTANDING GRADUATE STUDENT & MENTOR AWARDS IN POLYMER SCIENCE AND ENGINEERING SPONSORED BY CME Seunghyun Sim Bas van Genabeek Postdoc Researcher Caltech SyMO-Chem Takuzo Aida Bert Meijer Prof. Tokyo University Distinguished Professor Riken Group Director Eindhoven University . December 10, 2019 cmeacs.org In association with NASA 2:00 pm – Awards Presentation and Talk on Engineering self-assembly of protein polymers for functional materials. Seunghyun Sim – Proteins are monodisperse polymers that fold into a specific nanoscale structure. These state-of-art nanoscale machineries exert highly precise mechanical motions and process environmental inputs by the combination of allosteric effects. My research focuses on finding interdisciplinary solutions for designing a library of functional protein materials, mainly from the principles in supramolecular chemistry, molecular biology, and polymer science. In this symposium, I will discuss the design of protein-based macromolecular architectures in multiple dimensions, understanding their property for the therapeutic application, and in situ synthesis of extracellular protein network by living organisms for generating engineered living materials. Profile – Seunghyun Sim graduated from Seoul National University with B.S. degrees in Chemistry and Biological Sciences in 2012. She conducted her doctoral research with professor Takuzo Aida at the University of Tokyo and received her M.Eng. and Ph.D. in 2017. Her thesis work focused on engineering protein-based supramolecular nanostructures and functions. She is currently a postdoctoral fellow at California Institute of Technology in the lab of professor David Tirrell. -
Guide to the Enrico Fermi Collection 1918-1974
University of Chicago Library Guide to the Enrico Fermi Collection 1918-1974 © 2009 University of Chicago Library Table of Contents Descriptive Summary 4 Information on Use 4 Access 4 Citation 4 Biographical Note 4 Scope Note 7 Related Resources 8 Subject Headings 8 INVENTORY 8 Series I: Personal 8 Subseries 1: Biographical 8 Subseries 2: Personal Papers 11 Subseries 3: Honors 11 Subseries 4: Memorials 19 Series II: Correspondence 22 Subseries 1: Personal 23 Sub-subseries 1: Social 23 Sub-subseries 2: Business and Financial 24 Subseries 2: Professional 25 Sub-subseries 1: Professional Correspondence A-Z 25 Sub-subseries 2: Conferences, Paid Lectures, and Final Trip to Europe 39 Sub-subseries 3: Publications 41 Series III: Academic Papers 43 Subseries 1: Business and Financial 44 Subseries 2: Department and Colleagues 44 Subseries 3: Examinations and Courses 46 Subseries 4: Recommendations 47 Series IV: Professional Organizations 49 Series V: Federal Government 52 Series VI: Research 60 Subseries 1: Research Institutes, Councils, and Foundations 61 Subseries 2: Patents 64 Subseries 3: Artificial Memory 67 Subseries 4: Miscellaneous 82 Series VII: Notebooks and Course Notes 89 Subseries 1: Experimental and Theoretical Physics 90 Subseries 2: Courses 94 Subseries 3: Personal Notes on Physics 96 Subseries 4: Miscellaneous 98 Series VIII: Writings 99 Subseries 1: Published Articles, Lectures, and Addresses 100 Subseries 3: Books 114 Series IX: Audio-Visual Materials 118 Subseries 1: Visual Materials 119 Subseries 2: Audio 121 Descriptive Summary Identifier ICU.SPCL.FERMI Title Fermi, Enrico. Collection Date 1918-1974 Size 35 linear feet (65 boxes) Repository Special Collections Research Center University of Chicago Library 1100 East 57th Street Chicago, Illinois 60637 U.S.A. -
Notice of a Type Ii Decision on a Proposal in Your Neighborhood
Date: April 5, 2018 To: Interested Person From: Arthur Graves, Land Use Services 503-823-7803 | [email protected] NOTICE OF A TYPE II DECISION ON A PROPOSAL IN YOUR NEIGHBORHOOD The Bureau of Development Services has approved a proposal in your neighborhood. The mailed copy of this document is only a summary of the decision. The reasons for the decision are included in the version located on the BDS website http://www.portlandonline.com/bds/index.cfm?c=46429. Click on the District Coalition then scroll to the relevant Neighborhood, and case number. If you disagree with the decision, you can appeal. Information on how to do so is included at the end of this decision. CASE FILE NUMBER: LU 18-119651 HR: HISTORIC DISTRICT ALTERATIONS AND RENOVATIONS GENERAL INFORMATION Applicant: Sandra Burtzos | Portland Parks & Recreation | 503.823.5594 1120 SW 5th Ave #1302 | Portland OR 97204-1933 Owner: City of Portland | 1120 SW 5th Ave #1302 | Portland, OR 97204-1912 Additional Contact: Tim Clemen | Place | 503.334.1640 735 NW 18th Ave | Portland OR 97209 Site Address: Halprin Open Space Sequence Historic District – SW Portland Legal Description: BLOCK 145 LOT 1-8, PORTLAND; BLOCK A LOT 2 TL 900, SOUTH AUDITORIUM ADD; BLOCK B LOT 2 TL 1200, SOUTH AUDITORIUM ADD Tax Account No.: R667714430, R777500170, R777500660 State ID No.: 1S1E03BC 03400, 1S1E03CB 00900, 1S1E03CB 01200 Quarter Section: 3129 & 3229 Neighborhood: Portland Downtown, contact Rani Boyle at 503-725-9979. Business District: Downtown Retail Council, contact Sandra McDonough at 503-552- 6762. District Coalition: Neighbors West/Northwest, contact Mark Sieber at 503-823-4212.