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California Institute of Technology Biology and Biological Engineering Annual Report 2018 Introduction

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California Institute of Technology Biology and Biological Engineering Annual Report 2018 Introduction California Institute of Technology Biology and Biological Engineering Annual Report 2018 Introduction The annual report for Caltech's Division of Biology and Biological Engineering (BBE) presents major research accomplishments of faculty, students, and staff during the previous academic year. This report covers October 1, 2017 to September 30, 2018. Front Cover Illustration A chick embryo showing neural crest cells (green) emerging from the forming brain and migrating to the periphery Credit: Marianne Bronner Lab Back Cover Illustration A gastrula stage chick embryo showing BMP4 expression in green that defines the neural plate border. The purple signal is a modulator of BMP activity. Credit: Marianne Bronner Lab Front Cover Back Cover 1 News, Events, and People Annual Report | Biology and Biological Engineering | 2018 Press Releases 7 Annual Retreat 15 Lawrence L. and Audrey W. Ferguson Prize 19 2 News, Events, and People Annual Report | Biology and Biological Engineering | 2018 Dr. Nagendranath Reddy Biological Sciences Thesis Award 20 Professional Awards and Honors 21 Seminars 22 Named Lectures 28 3 News, Events, and People Annual Report | Biology and Biological Engineering | 2018 Symposiums 30 Current Graduate Students 34 Graduating Class of 2018 36 4 News, Events, and People Annual Report | Biology and Biological Engineering | 2018 Financial Support and Donors 40 Faculty and Research Staff 43 Division Staff 49 5 News, Events, and People Annual Report | Biology and Biological Engineering | 2018 Biology and Biological Engineering Faculty Research Updates 50 Biology and Biological Engineering Facilities 280 6 Press Releases Annual Report | Biology and Biological Engineering | 2018 10/10/2018 Faculty Join Caltech Caltech welcomes 12 faculty members who will join the Institute’s six divisions over the academic year, representing fields ranging from Cosmo chemistry and microeconomics to genome engineering and the philosophical underpinnings of quantum theory. Long Cai, David Van Valen, Kaihang Wang 10/08/2018 Time- Traveling Illusion Tricks the Brain Lori Dajose Caltech researchers show how sound can retroactively induce an optical… Shinsuke Shimojo 10/04/2018 Doris Tsao Named MacArthur Fellow Lori Dajose The MacArthur Fellowship is awarded to individuals of “outstanding talent.” 10/03/2018 Frances Arnold Wins 2018 Nobel Prize in Chemistry Whitney Clavin For her work on the directed evolution method of bioengineering enzymes, Frances Arnold has been awarded the Nobel Prize in…. 10/02/2018 Gradinaru receives NIH Director’s Award Lori Dajose The NIH Director’s Pioneer Award, given to “exceptionally creative… Viviana Gradinaru 9/26/2018 New Spatial Genomics Center at Caltech Lori Dajose Long Cai receives funding from the National Institutes of Health’s Human BioMolecular Atlas Program to establish this new center Long Cai, Michael Elowitz, Viviana Gradinaru, Mitchell Guttman, Lior Pachter, Ellen Rothenberg, Paul Sternberg, Matt Thomson, David Van Valen, Barbara Wold 9/22/2018 President Rosenbaum Highlights Postdocs as “Unsung Heroes” Ina letter to the Caltech community during Postdoc Appreciation Week, the President emphasizes the role this key group plays at the Institute. 7 Press Releases Annual Report | Biology and Biological Engineering | 2018 9/21/2018 Customer Circuits for Living Cells Lori Dajose Designer protein circuits program new functions in cells and take a step towards more precise disease treatments Michael Elowitz, Xiaojing Gao, Lucy Chong 9/17/2018 Caltech to Celebrate National Postdoc Appreciation Week September 17-21 Jon Nalick Events will honor contributions postdocs make to research 08/30/2018 Guiding Flight: The Fruit Fly's Celestial Compass Lori Dajose Fruit flies use the sun to avoid flying in circles, according to new research. Michael Dickinson, Katherine Leitch, Ivo Ros 08/13/2018 How Bacteria Breathe Arsenic Lori Dajose Determining the chemical structure of an enzyme that enables microbes to breathe arsenic compounds provides insight into how bacteria contribute to arsenic poisoning. Dianne Newman 07/13/2018 A Conversation with Matt Thomson Lori Dajose New assistant professor of computational biology Matt Thomson discusses how cells make decisions and work together. Matt Thomson 07/06/2018 Rothenberg Innovation Initiative Removes Risk, Leaves Lots of Reward Robert Perkins Researchers looking for a way to bridge the "valley of death" can compete for RI2 funding. 07/05/2018 DNA Neural Network Recognizes "Molecular Handwriting" Lori Dajose Caltech scientists have developed an artificial neural network out of DNA that can recognize highly complex and noisy molecular information. Lulu Quian 8 Press Releases Annual Report | Biology and Biological Engineering | 2018 06/22/2018 Probing Protein Processes: A Conversation with Rebecca Voorhees Lori Dajose Rebecca Voorhees is a newly appointed assistant professor of biology and biological Rebecca Voorhees 06/19/2018 How a Thieving Transcription Factor Dominates the Genome Lori Dajose Gene expression in developing cells is heavily influenced by group dynamics of DNA-binding proteins interacting with each other. Ellen Rothenberg, Xun Wang, Sarah Cohen 06/18/2018 Weighing the Planet's Biological Matter Lori Dajose A new study makes the first global estimates of the mass of life on Earth. Rob Phillips 06/07/2018 Ten Thousand Bursting Genes Lori Dajose Scientists can now image the activity of 10,421 genes at once within individual cells, using a new technique developed at Caltech. Long Cai, Wen Zhou, Yodai Takei, Chee- Huat Linus Eng, Jina Yun, Noushin Koulena, Eric Liaw 06/07/2018 The Cartography of the Nucleus Lori Dajose A new technique creates maps of the folded structures of DNA, RNA, and proteins within the cellular nucleus, revealing elegant "hubs" of organization. Mitchell Guttman, Sofia Quinodoz, Noah Ollikainen, Ali Palla, Elizabeth Detmar, Vickie Trinh, Mason Lai, Prashant Bhat, Yodai Takei 05/17/2018 How Social Isolation Transforms the Brain Lori Dajose Caltech researchers gain new insights into the brain mechanisms underlying the negative effects caused by long-term social isolation. David Anderson, Viviana Gradinaru 05/16/2018 Caltech Plant Biologist Receives Genetics Prize Lori Dajose Elliot Meyerowitz is a recipient of the 2018 Gruber Genetics Prize. 9 Press Releases Annual Report | Biology and Biological Engineering | 2018 Elliot Meyerowitz 05/11/2018 No Embryo Required: Studying Development in the Lab Lori Dajose Caltech scientists have engineered cells to create spatial patterns in a dish similar to those that occur during embryonic development. 05/09/2018 Solving Pieces of the Genetic Puzzle Lori Dajose A new approach developed at Caltech is an important step in cracking the code of mysterious, noncoding regions of DNA. Rob Phillips 05/08/2018 Frances Arnold Elected to American Philosophical Society Lori Dajose Caltech Professor who invented directed evolution for enzymes elected to American Philosophical Society. Frances Arnold 05/03/2018 A Gut Bacterium's Guide to Building a Microbiome Lori Dajose Many studies have linked the gut microbiome to health and disease. New research from Caltech reveals mechanisms utilized by gut bacteria to assemble a microbiome in the first place. Sarkis Mazmanian, Gregory Donaldson, Pamela Björkman 05/03/2018 Anderson Receives Neuroscience Prize Lori Dajose The 2018 Edward M. Scolnick Prize in Neuroscience is awarded to Caltech's David Anderson. David Anderson 04/24/2018 Caltech Alumna Awarded Soros Fellowship Lori Dajose Caltech alumna Suchita Nety will receive a Paul & Daisy Soros Fellowship for New Americans, receiving up to $90,000 in funding for her graduate studies. Suchita Nety 10 Press Releases Annual Report | Biology and Biological Engineering | 2018 04/18/2018 American Academy of Arts and Sciences Elects Two from Caltech Lori Dajose Michael Alvarez and Ellen Rothenberg, as well as two alumni, join 82 current Caltech faculty... Ellen Rothenberg 04/10/2018 Paralyzed Patient Feels Sensation Again Lori Dajose Using a tiny array of electrodes implanted in the brain's somatosensory cortex, Caltech scientists have induced sensations of touch and movement in the hand and arm of a paralyzed man. Richard Andersen 03/29/2018 Oka Receives Young Investigator Award Lori Dajose Yuki Oka is the 2018 recipient of the Ajinomoto Award for Young Investigators in Gustation. Yuki Oka 03/26/2018 Philanthropists Eli and Edythe Broad Give $5 Million to Honor Caltech President Emeritus David Baltimore Lori Dajose Entrepreneur, philanthropist, and life member of the Caltech Board of Trustees Eli Broad.. David Baltimore 03/12/2018 A Conversation with Caltech Entomologist Joe Parker Lori Dajose Joe Parker's childhood fascination with insects led him to a position as an assistant professor of biology at Caltech. Joe Parker 03/07/2018 Gift Enables Transformative Advances in Health Care Lori Dajose The Heritage Medical Research Institute (HMRI) has extended its partnership with Caltech for a minimum of three more years. Viviana Gradinaru, Mitchell Guttman, Sarkis Mazmanian, Mikhail Shapiro, Rebecca Voorhees 02/28/2018 Mapping the Neural Circuit Governing Thirst Lori Dajose Caltech researchers discover the wiring of the circuit in the mouse brain that drives and quenches thirst. Yuki Oka 11 Press Releases Annual Report | Biology and Biological Engineering | 2018 02/23/2018 Symposium to Honor Former Caltech President and Nobelist Lori Dajose A scientific symposium will be held on Friday, March 23, 2018, in honor of David Baltimore,
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