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Mizoram: Disease Burden Profile, 1990 to 2016 1990 life epectancy 2016 life epectancy emales 66 years ales 60 years emales years ales 6 years

How much did the under-5 mortality rate change from 1990 to 2016? How much did the under-5 mortality rate change from 1990 to 2016? Under-5Under-5 mortality mortality rate, both rate, sexes combined, both sexes 1990-2016 combined, 1990-2016

Mizoram nder- rae nder- rae Comaraie aerae rae loall or imilar Soio-demorahi Inde a Mizoram

150

100

Deaths per 1,000 lie births 50

9.2 0.6 The shaded 26.2 bands indicate 95% uncertainty intervals around 0 the estimates 1990 1995 2000 2005 2010 2016 Year What caused the most deaths in different age groups in 2016? PercentWhat contribution caused of the top 10 most causes deaths of death by in age different group, both sexes,age 2016groups in 2016? Percent contribution of top 10 causes of death by age group, both sexes, 2016

0−14 years [12% of total deaths] 15−39 years [13.7% of total deaths]

1 HIIDS erloi 3 3 DiarrhoeaRIoher 66 09 13 15 1 ND malaria 306 1 09 Maernal diorder 13 Neonaal diorder

6 Nutritional deficiencies

55 her ommniale dieae

34 11 Caner 15 103 Cardioalar dieae 44 46 5 Chroni reiraor dieae

Cirrhoi

Dieie dieae

Neroloial diorder 40−69 years [37.8% of total deaths] 70+ years [36.6% of total deaths] Diaeeroloodendo 6 29 her non-ommniale 2 ranor inrie 59 3 4 ninenional inrie 9 199 2 Siide iolene 66 53 her ae o deah 4 39 2 RI i lower reiraor ineion. 59 ND are neleed roial dieae. 30 15 ro i roenial dieae. Endo i endorine dieae. 123 21

11 141

India: Health of the Nation's States — The India State-Level Disease Burden Initiative. New : ICMR, PHFI, and IHME; 2017. ISBN 978-0-9976462-1-4. 1 roportion of total disease burden from Premature death 66 Disability or morbidity 5

What caused the most years of life lost by se in 2016? op 15 causes of YLLs, ranked by percent for both sexes combined, 2016

emales ales

Malaria Lower respiratory infections COPD* Road injuries Intestinal infectious diseases Diarrhoeal diseases Preterm birth complications Other neonatal disorders Ischaemic heart disease Tuberculosis HIV/AIDS Stomach cancer Tracheal, bronchus, and lung cancer Neonatal encephalopathy Stroke

10 5 5 25 0 0 25 5 5 10 Percent of total years of life lost due to premature mortality Percent of total years of life lost due to premature mortality

Communicable, maternal, neonatal, and nutritional diseases on-communicable diseases nuries

*COPD is chronic obstructive pulmonary disease. What caused the most years lived with disability by se in 2016? op 15 causes of YLDs, ranked by percent for both sexes combined, 2016

emales ales

Sense organ diseases* Low back & neck pain Migraine Iron-deficiency anaemia Skin diseases COPD* Other musculoskeletal Depressive disorders Anxiety disorders Preterm birth complications Diabetes Oral disorders Falls Drug use disorders Schizophrenia

100 5 50 25 0 0 25 50 5 100 Percent of total years lied ith disability Percent of total years lied ith disability Communicable, maternal, neonatal, and nutritional diseases on-communicable diseases nuries

*COPD is chronic obstructive pulmonary disease. *Sense organ diseases includes mainly hearing and vision loss.

2 Mizoram roportion of total disease burden from CDs 6 CDs 555 nuries 9

HowHow havehave the leading causescauses of of death death and and disability disability combined combined changed changed from from 1990 1990 to 2016? to 2016? ChangeChange in top 15 causes of of DALYs, DALYs, both both sexes, sexes, ranked ranked by by number number of ofDALYs, DALYs, 1990 1990–2016–2016

Commniale, maernal, Non-ommniale dieae Inrie ame or inreae dereae neonaal, and nriional dieae

Leading causes of DALYs 1990 Leading causes of DALYs 2016

Lower respiratory infections [9.9%] 1 1 COPD† [5.5%] Diarrhoeal diseases [6.7%] 2 2 Malaria [4.7%]* Malaria [5.1%] Lower respiratory infections [4.4%] Intestinal infectious diseases [4.6%] 4 4 Preterm birth complications [3.2%]* Tuberculosis [4.1%] Diarrhoeal diseases [3.1%] Preterm birth complications [3.7%] 6 6 Road injuries [3.0%] COPD† [3.2%] 7 7 Sense organ diseases‡ [3.0%] Other neonatal disorders [3.1%] 8 8 Intestinal infectious diseases [2.6%] Neonatal encephalopathy [2.6%] 9 9 Low back & neck pain [2.6%] Road injuries [2.2%] 10 10 Migraine [2.5%] Congenital birth defects [2.1%] 11 11 Skin diseases [2.3%] Sense organ diseases‡ [1.8%] 12 12 Iron-deficiency anaemia [2.3%] Skin diseases [1.8%] 1 1 Ischaemic heart disease [2.2%] Low back & neck pain [1.7%] 14 14 Tuberculosis [2.2%] Iron-deficiency anaemia [1.7%] 1 1 Other neonatal disorders [2.1%]* Migraine [1.7%] 16 22 Congenital birth defects [1.7%]* Ischaemic heart disease [1.3%] 20 2 Neonatal encephalopathy [1.6%]*

*Change not significant. COPD is chronic obstructive pulmonary disease. The percent figure in brackets next to each cause is Sense organ diseases includes mainly hearing and vision loss. DALYs from that cause out of total DALYs. Sel-harm refers to suicide and the nonfatal outcomes of self-harm.

WhatWhat caused the the most most death death and and disability disability combined combined across across age groups age groups in 2016? in 2016? PercentPercent ofof DALYs by age group, bothboth sexes,sexes, 2016 2016 20

[1.95]

15

10

Percent of total DALYs Percent [1.45] [0.73] [1.83] [0.65] [1.18] [0.58] [0.86] [0.97] [2.25] 5 [0.48] [2.81] [3.37] [3.85] [0.32] [0.33] [4.46] [5.02]

0

85+ (<1%) Under 5 (9%) 5 to 9 (10%) 10 to 14 (9%) 25 to 29 (9%) 30 to 34 (9%) 35 to 39 (7%) 40 to 44 (6%) 45 to 49 (5%) 50 to 54 (5%) 55 to 59 (4%) 60 to 64 (2%) 65 to 69 (2%) 70 to 74 (1%) 75 to 79 (1%) 15 to 19 (10%)20 to 24 (10%) 80 to 84 (<1%) Age Communicable, maternal, neonatal, and nutritional diseases on-communicable diseases nuries

The number in the bracket on top of each vertical bar is the ratio of percent DALYs to population for that age group. The number in parentheses after each age group on the x-axis is the percent of population in that age group.

Mizoram 3 What risk factors are driving the most death and disability combined? Contribution of top 10 risks to DALYs number, both sexes, ranked by number of DALYs, 1990-2016 What riskrisk factors factors are are driving driving the the most most death death and and disability disability combined? combined? ContributionBehavioural of of top top 10 10 risksEnvironmental/occupational risks to to DALYs DALYs number, number, both both sexes, sexes, rankedMetabolic ranked by number by number of DALYs,same of DALYs, 1990-2016 or increase 1990-2016 decrease

Behavioural Environmental/occupational Metabolic same or increase decrease

Risk factors 1990 Risk factors 2016 Risk factors 1990 Risk factors 2016

Malnutrition*Malnutrition* [32.2%] [22.4%]1 1 1 Malnutrition* [14.8%] 1 Malnutrition* [11.5%] WaSHAir pollution [15.2%] [8.3%]2 2 2 Air pollution [5.1%] 2 Tobacco use [11.0%] Air pollutionTobacco [7.7%] use [7.3%] High blood pressure [5.0%] Air pollution [5.4%] Tobacco use [3.6%] 4 4 Tobacco use [4.9%] WaSH [7.3%] 4 4 Alcohol & drug use [4.1%] Dietary risks [2.3%] Dietary risks [4.7%] High blood pressureDietary [2.2%] risks [2.5%]6 6 High fasting plasma glucose [4.0%]Dietary risks [3.6%] OccupationalAlcohol & risks drug [1.9%] use [2.4%]7 6 7 WaSH [3.9%] 6 High fasting plasma glucose [3.5%] AlcoholOccupational & drug use [1.6%] risks [2.4%]8 7 8 Alcohol & drug use [3.9%]7 High blood pressure [3.3%] High fasting plasma glucose [1.4%] 9 9 Occupational risks [2.6%] ImpairedHigh kidney blood function pressure [0.9%] [2.2%]10 8 10 Impaired kidney function8 [2.0%]Occupational risks [3.0%] High fasting plasma glucose [1.8%] 9 9 WaSH [2.9%] The percent figure in bracket next to each risk is DALYs from that risk out of total DALYs. *Malnutrition is child and maternal malnutrition. Impaired kidney function [1.3%] 10 WaSH is unsafe water, sanitation,10 Impaired and handwashing. kidney function [1.9%]

The percent figure in bracket next to each risk is DALYs from that risk out of total DALYs. *Malnutrition is child and maternal malnutrition. WaSH is unsafe water, sanitation, and handwashing.

How did the risk factors differ by se in 2016? Percent of total DALYs attributable to top 10 risks, ranked by percent for both sexes combined, 2016

emales ales

Malnutrition* Tobacco use Air pollution Alcohol & drug use Dietary risks High fasting plasma glucose High blood pressure Occupational risks WaSH Unsafe sex

15 10 5 0 0 5 10 15 Percent of years of life lost and years lied ith disability Percent of years of life lost and years lied ith disability

ehaioural nironmentaloccupational etabolic

*Malnutrition is child and maternal malnutrition. WaSH is unsafe water, sanitation, and handwashing.

4 Mizoram