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Bat ID Program 2017 June 23 Infectious Diseases of Bats Symposium June 29-July 1, 2017 University Center for the Arts 1400 Remington St Colorado State University Fort Collins, CO 80524 Infectious Diseases of Bats Symposium!Fort Collins, CO, USA 2 Infectious Diseases of Bats Symposium!Fort Collins, CO, USA Table of Contents Oral Presentations 4 Poster Presentations 13 Oral Presentation Abstracts 16 Poster Presentation Abstracts 39 Acknowledgments and Financial Support 55 Campus Map 56 List of Attendees 57 3 Infectious Diseases of Bats Symposium!Fort Collins, CO, USA Program Venue: University Center for the Arts, Colorado State University Thursday, June 29 5:30 p.m. Registration, PowerPoint file transfer, lobby, University Center for the Arts 6:00 p.m. Reception - Wine, beer and snacks, University Center for the Arts Friday, June 30 7:00 a.m. Registration, University Center for the Arts 8:00 a.m. Tony Schountz. Colorado State University. Welcoming remarks 8:10 a.m. Session I - Filoviruses (Joseph Prescott, Moderator) 8:10 a.m. Studies of horizontal transmission of Marburg virus among experimentally infected fruit bats Jonathan S. Towner1,2, Amy J. Schuh1, Brian R. Amman1, Megan E. B. Jones1,2, Tara K. Sealy1, Uebelhoer LS, Spengler JR, Stuart T. Nichol1 1Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, USA, 2Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, USA 8:30 a.m. Investigations of Long-term Protective Immunity against Marburg Virus Reinfection in Egyptian Rousette Bats Amy Schuh, Amman BR, Sealy TK, Spengler JR, Nichol ST and Towner JS Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA 8:45 a.m. Innate immune response to filoviruses and the role of filoviral interferon-inhibiting domains in bat and human cells Ivan V. Kuzmin1,2, Toni M. Schwarz3, Philipp A. Ilinykh1,2, Ingo Jordan4, Thomas G. Ksiazek1,2,5, Ravi Sachidanandam6, Christopher F. Basler3, 7, and Alexander Bukreyev1,2,5 1 Department of Pathology, The University of Texas Medical Branch, Galveston, Texas, USA; 2 Galveston National Laboratory, The University of Texas Medical Branch, Galveston, Texas, USA; 3 Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA; 4 ProBioGen AG, Berlin, Germany; 5 Department Microbiology & Immunology, The University of Texas Medical Branch, Galveston, Texas, USA; 6 Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA; 7 Current Address: Center for Microbial Pathogenesis, Institute for Biomedical Sciences, Georgia Research Alliance, Eminent Scholar in Virology, Georgia State University, Atlanta, Georgia, USA 9:00 a.m. Broad based surveillance for ebolaviruses: PREDICT in Sierra Leone, Liberia, and Guinea. Brian Bird1, Goldstein T1, Anthony S2, Gbakima A3, Saylors K3, Jean Louis F3, Wolking D1, Epstein J4, Karesh W4, Kreuder-Johnson C1, Mazet J1 One Health Institute UC Davis School of Veterinary Medicine1, Center for Infection and Immunity Columbia University2, Metabiota Inc.3, EcoHealth Alliance4 9:15 a.m. Quantifying signatures of resistance and tolerance to filoviruses in bat cell lines Cara E. Brook1, Melinda Ng2, Esther Ndungo, Rohit K. Jangra, Andrew P. Dobson, Andrea L. Graham, Bryan T. Grenfell, C. Jessica E. Metcalf1*, Kartik Chandran1* 1Department of Ecology and Evolutionary Biology, Princeton University; 2Department of Microbiology and Immunology, Albert Einstein College of Medicine *These senior authors contributed equally to this work. 4 Infectious Diseases of Bats Symposium!Fort Collins, CO, USA 9:30 a.m. Serologic evidence of exposure to filoviruses in fruit bats, Singapore Laing ED1, Ian H Mendenhall2, Linster M2, Low DHW2, Chen Y2, Yan L1, Sterling SL1, Borthwick S2, Neves ES2, Lim JSL2, Skiles M2, Lee BPY4, Wang LF2, Broder CC1, Smith GJD2, 5 Uniformed Services University, Bethesda, MD, USA1, Duke-National University of Singapore Medical School, Singapore2, North Carolina State University, Raleigh, NC, USA3, National Parks Board, Singapore4, Duke Global Health Institute, Duke University, Durham, North Carolina, USA5 9:45 a.m. Predicting undiscovered filovirus reservoirs and patterns of disease emergence David Hayman Molecular Epidemiology and Public Health Laboratory, Hopkirk Research Institute, Massey University, New Zealand 10:00 a.m. Break 10:30 a.m. Session II - Coronaviruses A (Joel Rovnak, Moderator) 10:30 a.m. Bats as possible animal origin of MERS-CoV Susanna K. P. Lau Department of Microbiology, The University of Hong Kong, Hong Kong, China 10:45 a.m. Rapid detection of MERS coronavirus ancestors in bats Prof. Patrick CY Woo Department of Microbiology, The University of Hong Kong, Hong Kong. 11:00 a.m. Global patterns in coronavirus diversity Simon J Anthony1,2,3; Johnson, C.K4; Greig, D.J4; Kramer, S1,5; Che, X1; Wells, H1; Hicks, A.L1; Joly, D.O6, 7; Wolfe, N.D6; Daszak, P3; Karesh, W3; Lipkin, W.I1,2; Morse, S.S2; PREDICT Consortium8; Mazet, J.A.K4; Goldstein, T4 1Center for Infection and Immunity, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY, 10032 (USA); 2Dept of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY (USA); 3EcoHealth Alliance, 460 West 34th Street, NY, New York (USA); 4One Health Institute & Karen C Drayer Wildlife Health Center, School of Veterinary Medicine, University of California Davis, California (USA); 5Dept of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY (USA); 6Metabiota, Inc. One Sutter, Suite 600, San Francisco, CA, 94104 (USA); 7Wildlife Conservation Society, New York, NY, (USA) 11:15 a.m. SARS coronavirus may have originated from frequent recombination events between SARS-like coronaviruses in a single horseshoe bat habitat Ben Hu1, Lei-Ping Zeng1, Xing-Lou Yang1, Xing-Yi Ge1, Wei Zhang1, Bei Li1, Dong-Sheng Luo1, Yun-Zhi Zhang2, Mei-Niang Wang1, Peter Daszak3, Lin-Fa Wang4, Jie Cui1, Zheng- Li Shi1 1 CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China; 2Yunnan Institute of Endemic Diseases Control and Prevention, Dali, China; 3EcoHealth Alliance, New York City, New York, USA; 4Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore. 11:30 a.m. A metagenomic approach identifying a MERS-related coronavirus in a bat from South Africa Marike Geldenhuys1, Marinda Mortlock1, Jaqueline Weyer2, Oliver Bezuidt3, Ernest Seamark4, Teresa Kearney5,6, Cheryl Gleasner 7, Tracey Erkkila7, Helen Cui7 and Wanda Markotter1 1 Centre for Viral Zoonosis, Department of Medical Virology, Faculty of Health sciences, University of Pretoria, Pretoria, South Africa. 2 Centre for Emerging, Zoonotic and Parasitic Diseases, 5 Infectious Diseases of Bats Symposium!Fort Collins, CO, USA National Institute for Communicable Diseases, Sandringham, South Africa. 3 Centre for Microbial Ecology and Genomics, University of Pretoria, Pretoria, South Africa. 4 AfricanBats NPC, South Africa and Centre for Wildlife Management, University of Pretoria, Pretoria, South Africa. 5 Animal, Plant and Environmental Sciences, University of the Witwatersrand, Johannesburg, South Africa 12:00 p.m. Lunch and Poster Session 2:00 p.m. Session III - Rhabdoviruses (Ashley Malmlov, Moderator) 2:00 p.m. New insights into the antiviral innate immune response of Desmodus rotundus Sarkis Sarkis, Marie-Claude Lise, Edith Darcissac, Stéphanie Dabo, Christine Neuveut, Benoît de Thoisy, Eliane Meurs, Anne Lavergne and Vincent Lacoste Institut Pasteur de la Guyane, French Guiana/ France 2:15 p.m. A comparative study of the autophagy pathway during virus infection of bat (natural) and human (accidental) host cells Eric D. Laing1, Spencer L. Sterling1, Dawn L. Weir1, Sasha E. Larsen2, Linfa Wang3, Brian C. Schaefer1, and Christopher C. Broder1 1Department of Microbiology, Uniformed Services University, Bethesda, MD, USA; 2Department of Pharmacology, Uniformed Services University, Bethesda, MD, USA; 3Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 2:30 p.m. Lagos bat virus in South Africa, 2013-2017 Jessica Coertse1, Le Roux, K.2, Richardson, E.3, White, W.3, Markotter, W.1 1Centre for Viral Zoonoses, Department of Medical Virology, Faculty of Health Sciences, University of Pretoria, South Africa; 2Allerton Provincial Veterinary Laboratory, Pietermaritzburg, KwaZulu-Natal, South Africa; 3KwaZulu-Natal Bat Interest Group, KwaZulu-Natal, South Africa 2:45 p.m. Characterization of a novel Rhabdovirus isolated from insectivorous bat (Pipistrellus kuhlii) in Italy Davide Lelli1, Alice Prosperi1, Chiara Chiapponi1, Paola Debenedictis2, Anna Maria Gibellini3, Stefania Leopardi2, Enrica Sozzi1, Dino Scaravelli4, Ana Moreno1, Antonio Lavazza1 1Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna, Via Bianchi 9 - 25124 Brescia, Italy; 2Istituto Zooprofilattico Sperimentale delle Venezie, OIE Collaborating Centre and National Reference Centre for Research on Infectious Diseases at the Animal-Human Interface, Viale dell’Università 10 - 35020 Legnaro (PD), Italy; 3Wildlife Rehabilitation Center WWF of Valpredina via Pioda n.1, 24060 Cenate Sopra(BG), Italy; 4University of Bologna, Department of Veterinary Medical Sciences, via Tolara di sopra 50 - 40064 Ozzano Emilia
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