Peer-Reviewed Journal Tracking and Analyzing Disease Trends pages 1–200 EDITOR-IN-CHIEF D. Peter Drotman Managing Senior Editor EDITORIAL BOARD Polyxeni Potter, Atlanta, Georgia, USA Dennis Alexander, Addlestone Surrey, United Kingdom Senior Associate Editor Timothy Barrett, Atlanta, GA, USA Brian W.J. Mahy, Bury St. Edmunds, Suffolk, UK Barry J. Beaty, Ft. Collins, Colorado, USA Martin J. Blaser, New York, New York, USA Associate Editors Sharon Bloom, Atlanta, GA, USA Paul Arguin, Atlanta, Georgia, USA Christopher Braden, Atlanta, GA, USA Charles Ben Beard, Ft. Collins, Colorado, USA Mary Brandt, Atlanta, Georgia, USA Ermias Belay, Atlanta, GA, USA Arturo Casadevall, New York, New York, USA David Bell, Atlanta, Georgia, USA Kenneth C. Castro, Atlanta, Georgia, USA Corrie Brown, Athens, Georgia, USA Louisa Chapman, Atlanta, GA, USA Charles H. Calisher, Ft. 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Frederick Sparling, Chapel Hill, North Carolina, USA Robert Swanepoel, Pretoria, South Africa The opinions expressed by authors contributing to this journal do not neces- sarily refl ect the opinions of the Centers for Disease Control and Prevention or Phillip Tarr, St. Louis, Missouri, USA the institutions with which the authors are affi liated. Timothy Tucker, Cape Town, South Africa All material published in Emerging Infectious Diseases is in the public do- Elaine Tuomanen, Memphis, Tennessee, USA main and may be used and reprinted without special permission; proper citation, John Ward, Atlanta, Georgia, USA however, is required. Mary E. Wilson, Cambridge, Massachusetts, USA Use of trade names is for identifi cation only and does not imply endorsement by the Public Health Service or by the U.S. Department of Health and Human ∞ Emerging Infectious Diseases is printed on acid-free paper that meets the requirements Services. of ANSI/NISO 239.48-1992 (Permanence of Paper) Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 18, No. 1, January 2012 January 2012 On the Cover Assessing Prion Infectivity of Dioskurides of Samos, Human Urine in Sporadic Musici Ambulanti, Creutzfeldt-Jakob Disease................... 21 Mosaic (c. 2200 years ago) S. Notari et al. (41 cm × 43 cm) Museo Archeologico Intracerebral injection of transgenic mice failed Nazionale, Piazza Museo to demonstrate prion disease transmission. Nazionale, Napoli, Italy About the Cover p. 196 High Prevalence of MDR TB, Swaziland, 2009–2010 .......................... 29 E. Sanchez-Padilla et al. One third of patients previously treated for tuberculosis had MDR TB. Synopsis Accelerating Control of Pertussis in England and Wales ..............................38 Intestinal Toxemia H. Campbell et al. Botulism in 3 Adults, Early completion of the primary vaccination schedule can reduce incidence among infants. Ontario, Canada, p. 72 2006–2008 ................................1 Y.D. Sheppard et al. An underlying gastrointestinal condition is a risk The 1918–19 Inf uenza Pandemic factor for this disease. in Boyacá, Colombia ............................ 48 G. Chowell et al. Timing of pandemic onset and prior immunity of Research populations varied by region. Serious Invasive Saffold Virus p. 111 Infections in Children, 2009 ...................7 Use of Lean Response to Improve A.C.Y. Nielsen et al. Pandemic Inf uenza Surge in This virus might have caused previously Public Health Laboratories ..................57 unexplained cerebral infections and deaths. J.L. Isaac-Renton et al. These tools enabled laboratory response to 10- fold increase in testing demands. Haemophilus infl uenzae Type b Disease, Transmission, and Vaccine Programs ................................ 13 Invasive Meningococcal M.L. Jackson et al. Capsular Group Y Disease, Flexible simulation model use can optimize England and Wales, 2007–2009 ...........63 vaccination programs and response to changes S.N. Ladhani et al. in vaccine supply. Increases may result from mutations that allow the organism to evade the immune system. Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 18, No. 1, January 2012 Historical Reviews Differential Mortality Rates by January 2012 Ethnicity in 3 Inf uenza Pandemics 109 Mutations I117V and I117M Over a Century, New Zealand ..............71 N. Wilson et al. and Oseltamivir Sensitivity of Pandemic (H1N1) 2009 Viruses Persistence of excess adverse outcomes A.C. Hurt et al. highlights need for improved response. 113 Multistate Outbreak of MDR TB Daily Newspaper View of Identif ed by Genotype Cluster Dengue Fever Epidemic, Investigation Athens, Greece, 1927–1931 ................. 78 P.M. Barry et al. C. Louis Controversy remains about possible dengue 117 Spoligotyping of Mycobacterium hemorrhagic fever during the epidemic. africanum, Burkina Faso M.K. Gomgnimbou et al. Dispatches p. 144 120 Evolution of Respiratory Syncytial 83 Unexpected Result of Hendra Virus Fusion Gene, Canada, Virus Outbreaks for Veterinarians, 2006–2010 Queensland, Australia J. Papenburg et al. D.H. Mendez et al. 125 Colpodella spp.–like Parasite 86 Candida spp. with Acquired Infection in Woman, China Echinocandin Resistance, France, C.L. Yuan et al. 2004–2010 E. Dannaoui et al. 128 Babesiosis among Elderly Medicare Benef ciaries, United p. 153 91 Outbreak of Leptospirosis after States, 2006–2008 Flood, the Philippines, 2009 M. Menis et al. A.T. Amilasan et al. 132 Foodborne Outbreak and 95 Legionella longbeachae and Nonmotile Salmonella enterica Endocarditis Variant, France N. Leggieri et al. S. Le Hello et al. 98 Emergence of Blastoschizomyces 135 Dengue Outbreak in Key West, capitatus Yeast Infections, Florida, 2009 Central Europe E.G. Radke et al. T. Birrenbach et al. 138 Rabies in Captive Deer, 102 Asymmetric Type F Botulism with Pennsylvania, 2007–2010 Cranial Nerve Demyelination B.W. Petersen et al. A. Filozov et al. 142 Oral Transmission of L-type BSE 105 MRSA USA300 at Alaska Native in Primate Model Medical Center, Anchorage, N. Mestre-Francés et al. Alaska, 2000–2006 M.Z. David et al. 146 Early Detection of Pandemic (H1N1) 2009, Bangladesh E. Azziz-Baumgartner et al. Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 18, No. 1, January 2012 174 Pulmonary Infection Caused by Mycobacterium conceptionense January 2012 150 Human Herpesvirus 8 176 Mycobacterium riyadhense Seroprevalence, China Pulmonary Infection, France T. Zhang et al. and Bahrain Another Dimension 179 Crimean-Congo Hemorrhagic Fever Virus in Ticks, 153 The Plague of Thebes in Southwestern Europe, 2010 Sophocles’ Oedipus Rex A.A. Kousoulis et al. 181 Crimean-Congo Hemorrhagic Fever Virus in Ticks from Imported Livestock, Egypt Letters 183 Cutaneous Leishmaniasis 158 Novel Prion Protein in BSE- Acquired in Jura, France affected Cattle, Switzerland p. 183 184 Visceral Leishmaniasis during 159 Hantavirus in Bat, Sierra Leone Italian Renaissance, 1522–1562 161 Porcine Epidemic Diarrhea in 186 Plague Epidemic in the Kingdom Suckling Piglets, China of Naples, 1656–1658 163 Bartonella quintana