FUNGICIDE CLASSIFICATION Repeated use of fungicides with the same mode of action can result in the selection of fungicide-resistant strains of plant pathogens. by PREMIX by MODE OF ACTION (MOA) This section lists premix fungicides by their trade names so you can identify the premix’s component This section groups fungicides by their mode of action to assist in the selection of fungicides 1) to maintain greater fungicides and their respective mode of action groups. diversity in fungicide use and 2) to rotate among effective fungicides with different modes of action to delay the development Refer to the Mode of Action section on the left of fungicide resistance. for more information.

ACTIVE FRAC FRAC MODE OF ACTION CHEMICAL ACTIVE PRODUCT EXAMPLES PREMIX CODE FAMILY INGREDIENT (Trade Name) INGREDIENT CODE

MITOSIS DISRUPTERS thiophanate-methyl 1 ACROPOLIS tetraconazole 3 MBC (methyl benzimidazole carbamates) Topsin, multiple generics 1 Thiophanates thiophanate-methyl B1: ß-tubuline assembly in mitosis and component in premix tetraconazole 3 AFFIANCE 11 CELL MEMBRANE DISRUPTERS propiconazole 3 AFRAME PLUS cyproconazole Alto and component in premix azoxystrobin 11 cyproconazole 3 Component of Quadris Top difenoconazole APROACH PRIMA and Miravis Top picoxystrobin 11 propiconazole 3 flutriafol Topguard and component in premix AVARIS azoxystrobin 11 Revysol, component of Revytek, mefentrifluconazole 3 Veltyma tebuconazole DMI (demethylation inhibitors)/ AZOXY TEB Triazoles azoxystrobin 11 triazoles metconazole Component of Headline Amp 3 3 G1: C14- demethylase in propiconazole Tilt, multiple generics AZOXYPROP XTRA biosynthesis (erg11/cyp51) propiconazole azoxystrobin 11 and component in premix potassium phosphite 33 Folicur, multiple generics CATAMARAN tebuconazole M5 and component in premix propiconazole 3 Domark, multiple generics tetraconazole COVER XL and component in premix azoxystrobin 11 tebuconazole 3 Triazolinthiones prothioconazole Proline and component in premix CUSTODIA azoxystrobin 11 RESPIRATION INHIBITORS prothioconazole 3 DELARO Pyridinecarboxamides boscalid Endura trifloxystrobin 11 tebuconazole 3 Pyridinyl-ethylbenzamides fluopyram Component of Propulse EVITO T fluoxastrobin 11 benzovindiflupyr Component of Trivapro flutriafol 3 SDHI (succinate dehydrogenase FORTIX fluoxastrobin 11 7 inhibitors)/carboxamides bixafen Component of Lucento pyraclostrobin 11 COMPLEX II: succinate-dehydrogenase fluxapyroxad Component of Priaxor, Revytek HEADLINE AMP Pyrazole-4-carboxamides metconazole 3 penthiopyrad Vertisan flutriafol 3 LUCENTO Adepidyn, component of Miravis Top, bixafen 7 pydiflumetofen Miravis Neo pydiflumetofen 7 Quadris, multiple generics 11 azoxystrobin MIRAVIS NEO azoxystrobin and component in premix Methoxy-acrylates propiconazole 3 QoI (quinone outside inhibitors)/ strobilurins picoxystrobin Aproach and component in premix difenoconazole 3 MIRAVIS TOP 11 C3: COMPLEX III: cytochrome bc1 Dihyrdro-dioxazines fluoxastrobin Aftershock, Evito pydiflumetofen 7 (ubiquinol oxidase) at Qo site tebuconazole 3 (cyt b gene) Methoxy-carbamates pyraclostrobin Headline and component in premix MUSCLE ADV chlorothalonil M5 Oximino-acetates trifloxystrobin Component in premix thiophanate-methyl 1 OVERRULE tebuconazole 3 OXIDATIVE PHOSPHORYLATION UNCOUPLERS flutriafol 3 PREEMPTOR 29 Oxidative phosphorylation uncouplers 2,6-dinitroanilines fluazinam Omega fluoxastrobin 11 fluxapyroxad 7 PRIAXOR UNKNOWN pyraclostrobin 11 phophorous acid 3 33 UNKNOWN Phosphonates Component in premix tetraconazole and salts PRIAXOR D fluxapyroxad 7

MULTI-SITE CONTACT ACTIVITY pyraclostrobin 11 prothioconazole 3 Inorganic copper (different salts) Badge and multiple generics PROPULSE M1 fluopyram 7 MULTI-SITE CONTACT ACTIVITY 1 Chloronitriles Bravo Weather Stik, multiple thiophanate-methyl M5 chlorothalonil PROTOCOL (Phthalonitriles) generics and component in premix propiconazole 3

QUADRIS TOP difenoconazole 3 QUADRIS TOP SBX Take Action is endorsed by the following organizations: azoxystrobin 11 QUILT propiconazole 3 QUILT XCEL azoxystrobin 11 mefentrifluconazole 3 REVYTEK fluxapyroxad 7 pyraclostrobin 11 prothioconazole 3 STRATEGO YLD trifloxystrobin 11 flutriafol 3 TOPGUARD EQ azoxystrobin 11 thiophanate-methyl 1 TOPSIN XTR tebuconazole 3 propiconazole 3 TRIVAPRO benzovindiflupyr 7 For more information and links to additional resources, visit www.IWillTakeAction.com azoxystrobin 11

Fungicides listed in this publication may not be registered for use in all states. Always read and follow the label directions. mefentrifluconazole 3 Fungicides are classified according to their mode of action, or numeric FRAC code. The list of FRAC codes was developed by the Fungicide Resistance Action Committee and is a technical classification of fungicide modes of action VELTYMA according to scientific data. For more information, please visit www.frac.info. pyraclostrobin 11 Technical editors for this poster include Kiersten Wise, Ph.D., University of Kentucky; Carl Bradley, Ph.D., University of Kentucky; Daren Mueller, Ph.D., Iowa State University; Damon Smith, Ph.D., University of Wisconsin-Madison; tebuconazole 3 Nathan Kleczewski, Ph.D., University of Illinois; and Heather Kelly, Ph.D., University of Tennessee. VIATHON This chart was developed with funding from the soy checkoff. potassium phosphite 33 The United Soybean Board and all Take Action partners, including the companies mentioned above, neither recommend nor discourage the implementation of any advice contained herein, and are not liable for the use or misuse of the information provided. ©2020 United Soybean Board [59783-1 2/20]