ANALYSIS OF PYRROLIZIDINE AND TROPANE ALKALOIDS ANALYSIS OF PYRROLIZIDINE AND TROPANE ALKALOIDS

Pyrrolizidine and tropane alkaloids are PYRROLIZIDINE ALKALOIDS  Scopolamine secondary plant substances, which are  Echimidine and Echimidine N-oxide  Scopolamine N-oxide produced by certain plants to protect (from April 2016) their selves against herbivores. There are  Erucifoline and Erucifoline N-oxide  Anisodamine around 600 known pyrrolizidine alkaloids  Europine and Europine N-oxide (PAs) including their N-oxides and more Using liquid chromatography with  Heliotrine and Heliotrine N-oxide than 200 different known tropane tandem mass spectrometry (LC-MS/ alkaloids (TAs).  Intermedine/Indicine and Inter- MS), depending on the substance and medine-N-Oxid/Indicine-N-Oxid In high concentrations PAs and TAs can matrix, the detection of secondary have a negative effect on health. While  Jacobine and Jacobine N-oxide phytochemicals is possible with limits of quantitation of 5.0 μg/kg to 0.1 μg/kg. some pyrrolizidine alkaloids are toxic or  Lasiocarpine and Lasiocarpine carcinogenic, tropane alkaloids present a N-oxide As part of the SGS Group, health risk for people with cardiovascular SGS INSTITUT FRESENIUS GmbH  Lycopsamine and Lycopsamine complaints, and particularly for babies enjoys an outstanding reputation with N-oxide and small children. Even low doses can manufacturers, consumers and retailers, cause drowsiness, nausea and heada-  Monocrotaline and Monocrotaline particularly in terms of the safety and ches. N-oxide quality of food, drinks and consumer PAs are found in more than 6,000 plant  Retrorsine and Retrorsine N-oxide products. Please get in touch with us if you need reliable analysis of pyrrolizidine species, such as tussilago, butterbur and  Senecionine and Senecionine and tropane alkaloids. ragwort. TAs are found in plants including N-oxide nightshades such as the datura and Contact us!  Seneciphylline and Seneciphylline belladonna. Despite good agricultural N-oxide practice, it is possible that during harvest the toxic substances present in the  Senecivernine and Senecivernine surrounding weeds can be inadvertently N-oxide CONTACT SGS INSTITUT FRESENIUS GmbH processed too.  Senkirkine Tegeler Weg 33 Our experts test herbs, cereals, herbal  Trichodesmine D-10589 Berlin food supplements, tea and honey, for the t +49 30 34607 700 following compounds: TROPANE ALKALOIDS f +49 30 34607 710  Atropine [email protected] www.sgsgroup.de  Atropine N-oxide

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