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MR Fingerprinting Turns Radiologists Into Detectives

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MR Fingerprinting Turns Radiologists Into Detectives ECR TODAY 2016 EUROPEAN CONGRESS OF RADIOLOGY DAILY NEWS FROM EUROPE’S LEADING IMAGING MEETING | THURSDAY, MARCH 3, 2016 3 9 17 25 HIGHLIGHTS CLINICAL CORNER TECHNOLOGY & RESEARCH COMMUNITY NEWS MR fingerprinting Diffusion-weighted MRI manufacturers A new feature at turns radiologists imaging breaks new put renewed emphasis ECR 2016: into detectives ground in abdomen on speed The Voice of EPOS™ BY TIMOTHY SPENCE MR fingerprinting turns radiologists into detectives Early tests on brain cancer patients show significant promise for the use of MR fingerprinting to produce previously unaainable quantitative information in a short time, accord- ing to Prof. Siegfried Tranig of the Medical University of Vienna, where new research on 10 volunteers has been carried out since ECR 2015. The results using an advanced MR imaging protocol and MR finger- printing showed that the T1 and T2 mapping of tissue provided by finger- printing was ‘beer visualised’ than in the standard protocol, said Tranig, medical director of the university’s Centre of Excellence in High Field These images of a patient with a glioblastoma in the le hemisphere of the brain show an MR fingerprinting T2 map, MR fingerprinting T1 MR and the chairman of the Euro- map, and conventional FLAIR-TSE and contrast-enhanced T1-SE images. (Provided by Prof. Siegfried Tranig) pean Imaging Biomarkers Alliance (EIBALL). The testing was conducted using five patients with malignant printing during today’s discussion that provides qualitative informa- The technique is also fast: results provide clues in the early detection brain tumours and an equal number of imaging biomarkers and their tion, fingerprinting can automat- from the Vienna tumour study of cancer. In addition, fingerprinting with low-grade gliomas. promise in the treatment of cancer ically provide a fast sequence that showed that the standard advanced may also yield cost savings because of “It’s my impression that we see and other chronic diseases. delivers quantitative diagnostic data MR imaging protocol took one hour the reduced mapping time involved, more changes by using MR finger- Fingerprinting has yet to be tested as well. for each patient, while the finger- and it is based on soware that can printing based on T1 and T2 maps in clinical seings, and Tranig “I believe that MR fingerprinting printing protocol could be done in be added to existing MR equipment, on this quantitative data. And acknowledges that there are diver- will help the radiological community five minutes. said Tranig. looking into the tumour, you see gent views amongst radiologists on to make this paradigm shi from MR fingerprinting could be advan- The Vienna researchers have been more details that are not shown on whether the technique can success- qualitative to quantitative imaging, tageous in other ways. Preliminary collaborating with other colleagues, standard imaging,” he explained, fully deliver stable and robust quan- and also to use quantitative data results suggest that there was low including Prof. Mark Griswold of the emphasising that the results of the titative data. Initially he was scep- more in their daily routine work,” variability of the T1 and T2 relaxation Department of Radiology at Case Austrian university’s 2015 tests are tical about the clinical potential of said Tranig, adding that the infor- times over multiple examinations of only preliminary. MR fingerprinting, but he now sees mation provided from fingerprints volunteers in Vienna, with the poten- ECR delegates have the opportu- it as potentially transformational. could be used to tailor treatment to tial to accurately monitor and evalu- nity to learn more about MR finger- Instead of a standard MR protocol patient needs. ate the progress of treatment, or even continued on page 3 myESR.org #ECR2016 BEST USE OF HYBRID IMAGING FOR PATIENTS www.eshi-society.org ECR TODAY | THURSDAY, MARCH 3, 2016 HIGHLIGHTS 3 BY MÉLISANDE ROUGER Distinguished U.K. radiologist to give honorary lecture on oncologic imaging In recognition of her major contributions to oncologic radiology and her dedication to the advancement of the field in Europe and beyond, Professor Andrea G. Rockall from London, United King- dom, has been invited to give the Wilhelm Conrad Röntgen Hono- rary Lecture ‘Imaging the invisible killer: towards personalisation of ovarian cancer care’. Andrea G. Rockall is Consultant position she held for twelve years. Rockall has authored or co-au- to Vienna for this excellent meeting Radiologist at the Royal Marsden During that time, she was appointed thored more than 100 publications in and networking with colleagues with Hospital and Visiting Professor Honorary Professor of Cancer Imag- peer-reviewed journals, three books similar interests,” she said. of Radiology at Imperial College ing at Bart’s Cancer Institute, Queen and numerous book chapters. Rockall has received many distinc- London, UK. Mary University London, before She was president of the Interna- tions for her work, including the She graduated in neuroanatomy taking up her current position. tional Cancer Imaging Society for Outstanding Teacher Award from at King’s College London in 1987 and Her interest in oncologic imaging 2015 and is a council member of the the International Society for Magnetic received her medical degree from grew under Prof. Rodney Reznek’s British Gynaecologic Cancer Society. Resonance in Medicine in 2014. King’s College Hospital Medical strong mentorship while working She is also currently a member of School in 1990. She was awarded the at St. Bartholomew’s Hospital. “Prof. the RCR Steering Group for Cancer “Active involvement in the ESR is Royal College of Radiologists’ (RCR) Reznek was leading developments Imaging and Reporting, and she very important to me. In particu- Rohan Williams Medal, the gold in gynaecologic cancer imaging in chairs the Female Pelvic Imaging lar, I value the mission of provid- medal award for the FRCR exami- the UK and there was a fantastic Working Group for the European ing high quality radiology educa- nation, in 1997. interaction with the surgeons and Society of Urogenital Radiology. tion ‘without borders’ through the She chose radiology as a career oncologists, which was very excit- In addition, she serves on several many ESR initiatives.” because of the central role imaging ing. My research followed this clinical commiees, including the European plays in the diagnostic pathway. interest,” she explained. Society of Gynaecologic Oncology’s Prof. Andrea G. Rockall from “I love the challenge of a difficult Rockall is currently chief investi- quality standards in ovarian cancer London, UK, will deliver today’s differential diagnosis and logically gator on three national multi-centre surgery committee, the RSNA Wilhelm Conrad Röntgen following the clinical and imaging studies: the MAPPING study, which Programme Commiee and the ACR Honorary Lecture on oncologic ‘clues’ to get to the correct diagnosis. is evaluating diffusion weighted O-RADS steering commiee. She has imaging. I was also drawn by the rapid pace of imaging, FDG and F-ethyl-choline also served as Chair of the ESR Stat- technological developments – as MRI PET/CT in nodal staging in cervix utes and Rules Subcommiee and as came into clinical use when I was a and endometrial cancer (funded by a member of the ESR Membership junior doctor in internal medicine,” Cancer Research UK); the MALIBO Subcommiee. she said. study, which is developing machine She started aending the ECR in Aer completing her training in learning in whole body MRI for 2003 when she presented one of her internal medicine, she started work- detection of metastatic disease first research studies on the diagnos- Don’t miss today’s Honorary Lecture ing as a registrar in radiology at St. (funded by National Institute for tic performance of MR lymphogra- Mary’s Hospital and then as a senior Health Research – NIHR); and the phy with USPIO in gynaecological Thursday, March 3, 12:15–12:45, Room A registrar in radiology at University MROC study, which is evaluating malignancies. “I was absolutely Wilhelm Conrad Röntgen Honorary Lecture College London Hospitals. In 2000, multi-parametric MRI in determin- delighted to be awarded Magna she was appointed Senior Lecturer ing treatment planning and staging Cum Laude for my presentation. » Imaging the invisible killer: and Consultant Radiologist at St. of ovarian cancer (also funded by Since that time, I have regularly towards personalisation of ovarian cancer care Bartholomew’s Hospital London, a NIHR). aended the ECR. I enjoy coming Andrea G. Rockall; London/UK continued from page 1 Western Reserve University in Prof. Marion de Jong of the Eras- Cleveland, Ohio, U.S., whose inter- mus University Medical Centre in New Horizons Session est in MR fingerprinting helped Roerdam sees targeted imaging as Thursday, March 3, 08:30–10:00, Room L8 spark the project with the European increasingly important in the field of NH 5 Imaging beyond morphology researchers. Griswold was a contrib- theranostics, which combines diag- uting author of an article published nostic and treatment approaches » Chairman’s introduction in the journal Nature in 2013 that to tailor patient care – or what she O. Clément; Paris/FR identified MR fingerprinting as a describes as “the right treatment for way to obtain simultaneous quanti- the right patient at the right time » MRI fingerprinting: the future? fication of tissue properties without and the right dose.” S. Tranig; Vienna/AT a surgical procedure.1 The authors “In nuclear medicine the concept » Receptor-targeted multimodal imaging also argued that fingerprinting has of theranostics is easy to apply and M. de Jong; Roerdam/NL been shown to reduce measure- to understand, because of an easy » Radiomics ment mistakes when teamed with switch of a diagnostic radionuclide L.S. Fournier; Paris/FR paern-recognition algorithms. to a therapeutic radionuclide on » Panel discussion: Imaging biomarkers: Apart from fingerprinting, ECR the same probe,” said de Jong, a key role for radiologists in the future? delegates will also learn about who is based in the Erasmus MC’s Prof.
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