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ISSN: 0974-1291 Volume 5 • Number 3 July–September 2010 CENTRAL COUNCIL FOR RESEARCH IN UNANI MEDICINE HIPPOCRATIC JOURNAL OF UNANI MEDICINE Volume 5, Number 3, July - September 2010 Hippocratic J. Unani Med. 5(3): 1 - 168, 2010 CENTRAL COUNCIL FOR RESEARCH IN UNANI MEDICINE Department of Ayurveda, Yoga & Naturopathy, Unani, Siddha and Homoeopathy (AYUSH) Ministry of Health & Family Welfare, Government of India Hippocratic Journal of Unani Medicine Chief Patron Minister for Health & Family Welfare, Government of India Patron Secretary, Department of AYUSH Ministry of Health & Family Welfare, Government of India International Advisory Board Prof. Ranjit Roy Chaudhury, New Delhi, INDIA Hakim Syed Khaleefathullah, Chennai, INDIA Hakim Saifuddin Ahmad, Meerut, INDIA Dr. Suraiya H. Hussein, Kuala Lumpur, MALAYSIA Dr. Fabrezio Speziale, Rome, ITALY Prof. Sami K. Hamarneh, Washington D.C., USA Dr. M. Abdullah, Lund, SWEDEN Dr. Saleem Khan, London, ENGLAND Mrs. Sadia Rashid, Karachi, PAKISTAN Dr. Marteen Bode, Amsterdam, THE NETHERLANDS Prof. S.G. Marketos, Cos, GREECE Mr. Rafiqul Islam, Dhaka, BANGLADESH Prof. Ikhlas A. Khan, USA Prof. R.D. Kulkarni, Mumbai, INDIA Dr. V.K. Gupta, New Delhi, INDIA Dr. G.N. Qazi, Jammu, INDIA Dr. Rashid Bhikha, Industria, SOUTH AFRICA Editorial Board Botany Chemistry Prof. Wazahat Husain, Aligarh, INDIA Dr. Sajid Husain, Hyderabad, India Prof. Khan Usmanghani, Karachi, PAKISTAN Modern Medicine Unani Medicine Prof. C.M. Habibullah, Hyderabad, INDIA Prof. Hakim Jameel Ahmad, New Delhi, INDIA Prof. Badri N. Saxena, New Delhi, INDIA Prof. A. Hannan, Karachi, PAKISTAN Prof. V.H. Talib, Dehradun, INDIA Prof. Anis A. Ansari, New Delhi, INDIA Dr. (Mrs.) Rajbala Yadav, New Delhi, INDIA Dr. (Mrs.) Neena Khanna, AIIMS, New Delhi Dr. K.S. Anand, New Delhi, INDIA Prof. Y.K. Gupta, AIIMS, New Delhi Dr. (Mrs.) Nandini Kumar, ICMR, New Delhi Pharmacology Prof. A. Ray, New Delhi, INDIA Dr. O.P. Agarawal, New Delhi, INDIA Editor Dr. Mohammed Khalid Siddiqui Director General Central Council for Research in Unani Medicine (CCRUM) Associate Editors Shamshad A. Khan, Deputy Director (Chemistry), CCRUM Sohail M. Adhami, Assistant Director (Statistics), CCRUM Khalid M. Siddiqui, Assistant Director (Unani), CCRUM Mehr-e-Alam Khan, Research Officer (Publication), CCRUM Technical Editor V.K. Singh, Consultant (Botany), CCRUM Editorial Office CENTRAL COUNCIL FOR RESEARCH IN UNANI MEDICINE 61 - 65 Institutional Area (Opposite ‘D’ Block), Janakpuri, New Delhi - 110 058, India Tel.: +91-11-28521981, 28525982, 28525983, 28525831/52/62/83/97, 28520501, 28522524 • Fax: +91-11-28522965 Web site: www.unanimedicine.org • E-mail: [email protected] & [email protected] Annual Subscription: Rs. 300/- (India) US$ 100/- (Other countries) Single Issue: Rs. 150/- (India) US$ 50/- (Other countries) Payments in respect of subscription may be sent by bank draft marked payable to Director, CCRUM, New Delhi. On behalf of Central Council for Research in Unani Medicine (CCRUM) published and printed by Dr. Mohammed Khalid Siddiqui, Director, CCRUM at CCRUM headquarters, 61 - 65 Institutional Area (Opposite ‘D’ Block), Janakpuri, New Delhi - 110 058 and printed at Rakmo Press Private Limited, C - 59 Okhla Industrial Area Phase - I, New Delhi - 110 020 Contents 1. Efficacy of Post Beekhe Madar (Calotropis gigantea) Root Bark in Experimentally Induced Diarrhoea ........................................................................................................................................ 1 Rashid Ali, K.M.Y. Amin, Ghufran Ahmad, Abdul Wadud and Nasreen Jahan 2. Clinical Evaluation of Unani Compound Coded Drug (UNIM-353) on Zeequn Nafas (Bronchial Asthma): A Preliminary Clinical Study ....................................................................................... 9 Munawwar H. Kazmi, Masroor Ali Qureshi, Nirmala Devi, Parvez Khan, Humaira Bano and Najma A Shaikh 3. Physico-chemical and Phytochemical Studies of Majoon-e-Baladur: A Herbal Formulation ................. 15 N.A. Khan, M. Muzaffar, I.A. Qasmi, M. Nasiruddin and M.M. Haque 4. Ethnobotanical Survey of Khammam and Bhadrachalam Forests of Andhra Pradesh......................... 21 V.C. Gupta, Mushtaq Ahmad, V.K. Singh, Aminuddin and M.D. Alam 5. Standardization of Habb-e-Man-e-Hamal – A Unani Contraceptive Pill ................................................. 31 Kiran Negi, Kunal Sajwan and M.S.Y. Khan 6. Ethnopharmacological Study of the Champawat Forests of Kumaon Region, Uttarakhand................. 39 Zaheer Anwar Ali, Sarfraz Ahmad, Mokhtar Alam and Latafat Ali Khan 7. Kala-Azar (Leishmaniasis) and its Management in Unani Medicine ...................................................... 51 M.U. Azhar, N. Quddusi, N. Anjum, K.M. Siddiqui and M.K. Siddiqui 8. Role of Chromatography in the Identification and Quality Control of Herbal Drugs 1. HPTLC Finger Prints of “Qurs-e-Kundur”: a Unani Compound Formulation ..................................... 71 N.M.A. Rasheed, M. Ayesha, M.A. Shareef, M.D. Alam, V.C. Gupta, Shamshad Ahmed Khan, Shamsul Arfin and Aminuddin 9. A Study of Anti-salmonella Activity of Neem (Azadirachta indica) Stem Bark using different extracts ............................................................................................................ 87 Ayesha Mateen, V.C. Gupta, M.A. Waheed, N.M.A. Rasheed, Shamshad Ahmed Khan, Shamsul Arfin and Aminuddin 10. A Chemical Standardization of a Unani Single Drug – 1. Ood-e-Saleeb (Paeonia emodi Wall.) and Evaluation of its Antimicrobial Activity Against Bacterial Strains ............... 93 N.M.A. Rasheed, M. Ayesha, M.A. Waheed, M.D. Alam, Shamshad A. Khan and S. Arfin 11. Effect of Kaknaj (Physalis alkekengi Linn Fruit) on Gentamicin-Induced Acute Renal Impairment in Rats .................................................................................................................................... 107 Wasim Ahmad, N.A. Khan, Ghufran Ahmad and Shamshad Ahmad 12. Anti-oxidant Activity of Zafran (Crocus sativus L.) with Vitamin E as Referent – An Experimental Study............................................................................................................................. 119 Kunwar Mohd. Yusuf Amin, Naeem A. Khan, Shameem J. Rizvi, S.M. Kashif Zaidi, Naheed Banu and Sauduz Zafar Ali 13. Botanical and Physico-chemical Standardization of Sufoof-e-Bers – a Polyherbal Unani Drug of Repute ....................................................................................................... 131 Shamima Hashmi and R.H. Zuberi 14. Standardization of a Nervine Unani Formulation – Habb-e-Hudar ....................................................... 141 Shariq Shamsi, Tajuddin and S.H. Afaq 15. Morpho-anatomical Studies on Malaxis acuminata D. Don – An Endangered Medicinal Orchid ............ 149 Sunil Dutt, R.K. Bhanwra, Karan Vasisht, Maninder Karan and Rajeev Kr. Sharma 16. Hudar: Rheumatoid Arthritis in Unani System of Medicine, a Review ..................................................... 163 Ashhar Qadeer and Mohammad Maaz EDITORIAL On account of the world-wide interest in the personal health and use of plant based drugs, the research activities in the traditional drugs have considerably increased. Over the years, a large number of traditional drugs, mainly herbal, have been subjected to clinical, pharmacological, phytochemical and pharmaceutical studies in an effort to validate them and prove their medical efficacy and safety. All these investigations have yielded extensive and valuable findings and insights, and there is a need for wide exchange of this information among scientists engaged in the development of new drugs of natural origin. Unani system of Medicine, although originated in Greece, is one of the recognized systems of medicine of the country. Although, the Unani medicine have been in use for centuries and are known for their therapeutic efficacies, there is a need to scientifically establish their efficacy and safety in order to achieve global acceptance. Organized research work in this system was, therefore, a need of the hour. In post independent era, Central Council for Research in Unani Medicine, through its clinical, drug research, literary research, survey & cultivation of medicinal plants programme is contributing significantly for last three decades. Vitiligo, Sinusitis, Filariasis, Eczema, Malaria, Infective Hepatitis, Asthma, are some of the conditions where Unani therapies have earned recognition after scientific validation. The Council has been publishing the Hippocratic Journal of Unani Medicine (HJUM), mainly to bring out fundamental and applied aspects of Unani Medicine. The journal also publishes recent advances in other related sciences and traditional medicines as well as different streams of medical sciences, which have bearing on validation and scientific interpretation of various concepts and strengths of Unani medicine. In view of an overwhelming response, the journal earlier published twice a year, its periodicity has now been changed to quarterly w.e.f. January 2008 to accommodate more articles for quick dissemination of research data among scientific community. The journal has sufficient room for invited articles from luminaries of modern medicine and sciences as well as scholars of Unani medicine. The broad areas being covered include clinical research on single and compound Unani drugs, validation of regimental therapy, Clinical and experimental pharmacological studies, standardization of single and compound drugs, development of standard operating