2011-2012 Annual Report

2011-2012

ANNUAL REPORT

Department of Internal Medicine

University of New Mexico School of Medicine

Pope L. Moseley, M.D. Regents’ Professor and Chair

TABLE OF CONTENTS Key Departmental Accomplishments ...... 5 Offices of the Vice Chairs of the Department ...... 13 Office of Education ...... 15 Graduate Medical Education ...... 17 Undergraduate Medical Education ...... 20 Office of Faculty Development ...... 23 Office of Quality, Safety & Clinical Operations ...... 27 Office of Research ...... 33 Office of VA Affairs ...... 43 Academic Divisions ...... 51 Cardiology ...... 53 Clinical Immunology and Rheumatic Diseases...... 65 Endocrinology ...... 71 Epidemiology and Preventive Medicine ...... 81 Gastroenterology and Hepatology ...... 97 General Internal Medicine ...... 111 Geriatrics and Palliative Medicine ...... 125 Hematology/Oncology ...... 131 Hospital Medicine ...... 147 Infectious Diseases ...... 155 Nephrology ...... 167 Pulmonary, Critical Care and Sleep Medicine ...... 177 Centers and Projects ...... 191 Allergy Service ...... 193 Center for Global Health ...... 197 Center for Occupational and Environmental Health Promotion ...... 207 Center for Project ECHO ...... 211 Academic Directory ...... 223 Internal Medicine Faculty 2011-2012 ...... 225 Internal Medicine Fellows 2011-2012 ...... 233 Internal Medicine Housestaff 2011-2012 ...... 236 Housestaff – Program Year 1 ...... 236 Housestaff – Program Year 2 ...... 238 Housestaff – Program Year 3 ...... 239

KEY DEPARTMENTAL ACCOMPLISHMENTS ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Pope L. Moseley, M.D. Reva A. Skelton Endowed Research Professor Regents' Professor of the University of New Mexico Chairman, Department of Internal Medicine

KEY DEPARTMENTAL ACCOMPLISHMENTS

Resource Management has continued to refine its financial management, enhancing the Divisions Chiefs’ role in the financial success of his/her Division, with the establishment of a comprehensive revenue distribution model focusing on output and not historical allocations. The most important element of this change has been to align responsibility with authority at the divisional level, mimicking the relationship of Dean to Chair, at the departmental level between Chair and Chief. The Department has now gone through an extensive financial reporting redesign, engaging and achieving buy-in at all levels of the institution, which has dramatically reduced the complexity of the financial analyses and reporting for the Department and Divisions, separating operating activities from programmatic activities. These financial philosophies are a direct result of some of our improved clinical and research metrics.

The Department has continued to improve our patient care documentation. Work RVUs increased 4.2% over the prior year which is a reflection of the increased Clinical FTE. Collections per work RVU increased over 8% from FY10 and 2% from FY11. Clinical Contracts through the UNMMG increased 32% over FY11.

Our research and contract total awards have consistently topped $30 million for the last 6 years (includes extramural awards received by DoIM faculty in the UNM Cancer Center, Clinical and Translational Science Center, and Department faculty located at Albuquerque VA Medical Center). F&A generated on external funding overall since FY10 has increased over 5%. Faculty salaries on extramural sources increased 14% in FY12 over.

The Department continues to carefully manage its resources. In FY12 the Department secured $6 Million gift to establish a Kidney research Institute in the Department of Internal medicine. The Institute will focus on research and training to prevent and treat end stage renal disease in New Mexico.

Project ECHO receives $8.5 million HHS Health Care Innovation Award

The Department of Internal Medicine’s Project ECHO will receive nearly $8.5 million over three years from the U.S. Department of Health and Human Services Health Care Innovation Awards. Project ECHO is a transformative model of medical education and health care delivery that brings high-quality care to very sick patients wherever they live. It was created by social innovator Sanjeev Arora, M.D. ARORA The award, one of 26 nationwide, is administered through HHS’s Center for Medicare and Medicaid Innovation, and estimated to save more than $11 million in health care costs over the same time period. The department says the 26 awardees were selected for offering innovative solutions to health care challenges facing their communities and a focus on creating a well-trained health care workforce. Under the grant, UNM will identify 5,000 high-cost, high-utilization, high-severity patients in New Mexico and Washington State, and use a team of primary care “intensivists” trained to care for complex patients with multiple chronic diseases, working with area managed care organizations and care providers. Project ECHO will train as many as 300 workers to help increase primary care physicians’ capacity to treat and manage complex patients.

CLINICAL PRACTICE

UNM Cardiology Clinic The UNM Cardiology Clinic located at 4808 McMahon Blvd., NW, opened Monday, July 18, 2011. Patients have access to a full range of outpatient cardiovascular diagnostic services provided by a team of board certified cardiologists, specialized technicians, and office staff using the most advanced equipment and technologies. Cardiologist Robert DuBroff, M.D., serves as lead physician and is joined by UNM faculty Cardiologist Abinash Achrekar. The UNM Cardiology Clinic is part of the award-winning UNM Cardiology team that has earned several honors and designations, including best in state and highest UNM CARDIOLOGY CLINIC ranked academic hospital in the nation for heart attack treatment response time by the U.S. Department of Health and Human Services and University HealthSystem Consortium.

Arthritis outreach The Arthritis Foundation, Greater Southwest Chapter, announced collaboration with the Division of Rheumatology, Department of Internal Medicine to support their outreach efforts with the goal of expanding and developing care for those with arthritis, especially in rural communities. “This is an important grant. These funds will enable us to open an evening clinic and improve access for the BANKHURST thousands of New Mexicans who suffer from these conditions,” said UNM Rheumatology Division Chief Dr. Arthur Bankhurst, M.D., who directed the project.

RESEARCH AND SCHOLARSHIP

Excellence in Research Award HSC Office of Research and the Excellence in Research Award Committee announced the award recipient of the Third Annual Research Day Ceremony. Colleagues were nominated by their peers then selected by a faculty committee for outstanding contributions in research. David Schade, M.D., Vice Chair for Research in the Department of Internal Medicine and Chief of the Division SCHADE of Endocrinology & Metabolism was recognized for Clinical Science in the Department of Internal Medicine.

Celebrex and Lung Cancer A new study by Jenny Mao, Section Chief in the Division of Pulmonary, Critical Care and Sleep Medicine in the Department of Internal Medicine, and colleagues at UCLA suggests that Celebrex, a common anti-inflammatory drug used to treat arthritis and other diseases, may prevent lung cancer in former smokers. Published in the July issue of the scientific journal Cancer Prevention Research, MAO the study found that Celebrex – or Celecoxib, as it is known generically – decreased cell proliferation in the air passages of former heavy smokers. Such cell proliferation may contribute to the development of lung cancer. Study participants who received Celebrex for six months showed a 34 percent average decrease in a biomarker for cell proliferation, as well as other bronchial benefits. While still preliminary, the results warrant further investigation in a larger clinical trial. “These findings are very exciting,” said Mao, chief and professor of medicine at the New Mexico VA Health Care System and member of the UNM Cancer Center. “There are 45 million former smokers in the US. These individuals have already significantly lowered their lung cancer risk by following medical advice and quitting, but they still have an elevated level of risk. Researchers have been working hard to find ways

6 to reduce lung cancer risk in this group. Our latest study provides further evidence to support the continued evaluation of Celebrex for lung cancer chemoprevention in these high-risk individuals.”

INTERNAL MEDICINE FACULTY RECOGNITION

Best Doctors in America selection Best Doctors in America 2011-12 announced its Best Doctors selection for New Mexico. An exhaustive peer review determines the physicians. Only those who earn the consensus support of their peers as well as meet additional qualification criteria are included. Congratulations to the following doctors in the Department of Internal Medicine:

 William Abeyta, M.D., General Internal Medicine  Arthur Bankhurst, M.D., Rheumatology  Amanda A. Beck, M.D., Sleep Medicine  Jessica B. Bigney, M.D., General Internal Medicine  Lee K. Brown, M.D., Sleep Medicine  Mark R Burge, M.D., Endocrinology and Metabolism  George D. Comerci, Jr., M.D., General Internal Medicine  Frederick Hashimoto, M.D., General Internal Medicine  Carla J. Herman, M.D., Geriatrics  Robert A. Hromas, M.D., Medical Oncology and Hematology  Fa-Chyi Lee, M.D., Medical Oncology and Hematology  Edward N. Libby, III, M.D., Medical Oncology and Hematology  Melvina L. McCabe, M.D., Geriatrics  Ann Morrison, M.D., General Internal Medicine  Yehuda Z. Patt, Medical Oncology and Hematology  David S. Schade, M.D., Endocrinology and Metabolism  Wilmer L. Sibbitt, M.D., Rheumatology  Carolyn M. Voss, General Internal Medicine

Medical Education Scholars (MES) Program

The Office of Undergraduate Medical Education named several Internal Medicine faculty members for the 2011- 2012 Medical Education Scholars (MES) Program, which was initiated in 1998 as a means of ensuring a continuum of educational leadership at the UNM SOM:  Esme Finlay, M.D.  Erik Paul Kraai, M.D.  Eleana Zamora, M.D.

Denece Kesler, M.D., MPH: Chair-elect forABPM

Denece Kesler, M.D., MPH, Professor in the Department of Internal Medicine, and Director of UNM’s Center for Occupational and Environmental Health Promotion and it’s Preventive Medicine Training Program was voted Chair-elect for the American Board of Preventive Medicine (ABPM), where she will serve for one year followed by a four-year term as ABPM’s Chairperson. Dr. Kesler has been on KESLER the ABPM Board for 4 years, and currently is servicing as Chair of the Certification Committee.

Diane Klepper, M.D.: Educator Advocate Leader The Diane Klepper, M.D., Endowed Professorship Fund has been established by the UNM Foundation, established through a flexible deferred charitable gift annuity from Janet Kiehle Allen, M.D. For 31 years, Dr. Klepper served the UNM School of Medicine as the Assistant and Associate Dean for Admissions and Student Affairs. She retired from that position in 1999, but has stayed KLEPPER involved with the School of Medicine as a working retiree, continuing her clinical involvement in the Department of Internal Medicine as a Pulmonary Medicine Specialist and a teacher in the Undergraduate Medical Education Program.

Beverly Kloeppel, M.D., MBA: ACHA Board of Directors Beverly Kloeppel, M.D., MBA, Department of Internal Medicine, Director, Student Health and Counseling, was elected to the American College Health Association (ACHA) Board of Directors as Region I Representative for the 2012-2014 ACHA program years. ACHA is excited about the perspective and insights that she will bring to governing and policy decisions, and the professional KLOEPPEL and personal rewarding experience for her, her board colleagues and the association’s national office staff.

Jarrod Frizzell, M.D.: Ervin W. Lewis Resident Khatali Teaching Award Winner Congratulations to Jarrod Frizzell, M.D., on being selected by the Class of 2012 as an Ervin W. Lewis Resident Khatali Teaching Award Winner. Of the more than 700 housestaff at the School of Medicine, the graduating class felt that Dr. Frizzell modeled what it means to be an excellent educator, physician and mentor. It is the highest honor given by a graduating class at the School of FRIZZELL Medicine and speaks volumes to his dedication and commitment to students.

Anne Simpson, M.D.: African American/Black Healthcare Professionals Alliance Anne Simpson, M.D., a Professor in the Division of Geriatrics, was recently honored by the New Mexico Office of African American Affairs for her work within the community, including helping to create the newly formed African American/Black Healthcare Professionals Alliance. The group seeks to address the social determinates of health by providing mentorship and advocacy to all SIMPSON students, African American/Black students in particular, and by building social and political capital in support of better health outcomes for African American/Blacks in New Mexico. Dr. Simpson is Executive Director for the UNM Health Sciences Center, Center of Excellence for African American Health, and Rust Professor and Director of the UNM School of Medicine Institute for Ethics.

Craig Timm, M.D.: Senior Associate Dean for Education Dr. Craig Timm, a Professor in the Division of Cardiology, has accepted an offer to serve as the permanent Senior Associate Dean for Education in the University of New Mexico School of Medicine. Craig has done an excellent job in his interim role and he enjoys broad support from the Committee of Chairs. He is a proven leader and a strong advocate for all of our educational TIMM programs.

Faculty milestones  Effective March 1, 2012, Dr. Bart Cox accepted the role of Medical Director of Cardiology’s In-patient Services on 7S.  After 17 years of leadership of the Division of Infectious Disease, Dr. Gregory Mertz stepped down as of Chief January 3, 2012.

Remembering Corey Tancik. M.D. In February 2012, Dr. Corey Tancik died suddenly from a medical illness. Dr. Tancik graduated from the University of Colorado School of Medicine in 1985 before moving to UNM to complete his internal medicine residency and ID fellowship from 1985-1990. He worked in private practice in Albuquerque and for the New Mexico Department of Health as the State TB control officer, followed by positions TANCIK as the Assistant Director of TB Control for the Los Angeles County Health Department and as an ID faculty member at the University of Arkansas. He returned to UNM in 2001 as an Associate Professor of Internal Medicine in the ID Division. He served as Interim ID Section Chief at the VA from 2002-3 and 2004-7 and as the Infectious Diseases Fellowship Program Director from 2004 through 2010. He was promoted to Professor of Internal Medicine in July 2008. He served as an internal medicine ward attending and inpatient and outpatient ID consult attending at both UNMH and the VA. In 2011 he moved to a full-time position in the hospitalist division at the VA but maintained an active role in the VA ID section. Corey was a highly-regarded clinician, teacher and administrator. He will be remembered for the superb care he provided for his patients, and for his steadfast devotion to medical education.

KEY NEW FACULTY HIRES OR APPOINTMENTS  Mathew Bouchonville, M.D., Assistant Professor/Endocrinology  Alan Tomkinson, Ph.D., Professor/Hematology-Oncology  Alisha Parade, M.D., Visiting Instructor/General Internal Medicine  Michael Gilles, M.D., Assistant Professor/Gastroenterology  Jennifer Benson, M.D., Assistant Professor/General Internal Medicine  Hui Yang, Ph.D., Research Assistant Professor/Hematology-Oncology  Annahita Sallmyr, Ph.D., Research Assistant Professor/Hematology-Oncology  Alan Tomkinson, Ph.D., Assistant Professor/Hematology-Hematology  Sheila Modi, M.D., Assistant Professor/General Internal Medicine  Katya Calvo, M.D., Visiting Assistant Professor/Infectious Disease  Rishi Menon, M.D., Assistant Professor/General Internal Medicine  Robert DuBroff, M.D., Assistant Professor/Cardiology  Jens Langsjoen, M.D., Assistant Professor /General Medicine-Hospitalist  Savitri Aguiar, M.D., Assistant Professor/General Medicine-Hospitalist  Dulcinea Quintana, M.D., Assistant Professor/Hematology-Oncology  Kevin Kolendich, M.D., Assistant Professor/Gastroenterology  Roderick Fields, M.D., Assistant Professor/Rheumatology  Richard Snider, M.D., Assistant Professor/Cardiology VA  Michael West, M.D., Assistant Professor/Cardiology VA  Ivan E, Correa, M.D., Assistant Professor/Geriatrics VA  Prashant Nighot, Ph.D., Research Assistant Professor/Gastroenterology  Herbert Davis, Ph.D., Research Assistant Professor/Epidemiology  Shuhong Guo, Ph.D., Research Assistant Professor/Gastroenterology  David A. Gonzales, M.D., Assistant Professor/Hospital Medicine SRMC  Rebecca Bair, M.D., Assistant Professor/Hospital Medicine  Betty Newvill, M.D., Assistant Professor/Hospital Medicine

ANNUAL SERVICE AWARD Seventeen employees of the Department of Internal Medicine were recognized at the Annual Service Award Ceremony held April 24, 2012:

35 Years of Service 20 Years of Service David S. Schade, M.D. Ysela Gonzales T. Craig Timm, M.D. Bronwyn Wilson, M.D

25 Years of Service 15 Years of Service Richard E. Crowell. M.D. Peggy A. Beeley, M.D. Patricia L. Kapsner, M.D. Melissa A. Cordero Christina (Tina) J. Lujan Elizabeth Duran-Valez Mark R. Schuyler, M.D. Isabel Hale Michelle S. Harkins, M.D. Bruce L. Horowitz, M.D. Gary K. Iwamoto, M.D. Jennifer R. Jernigan, M.D. Janice Knoefel, M.D.

CENTRAL ADMINISTRATION

CENTRAL ADMINISTRATION ACCOMPLISHMENTS Happy and Health Heart Celebration: Dr. David Schade from the Department of Internal Medicine, Division of Endocrinology presented Part II of his “Preventing a Heart Attack” at the Happy and Health Heart Celebration Friday, February 3, 2012. Following Dr. Schade’ presentation there was a workshop on “Wear Your Heart on Your Hat Workshop” and “Heart Health Fun Facts.” The Department of Internal Medicine uses a “Dress Red “theme in conjunction with the American Heart Association‘s Go Red for Women to include both women and men in the celebration. Thanks to everyone who participated in making this an enjoyable and educational time for all.

Holiday Giving Project: Each year, DoIM Administration coordinates an annual Holiday Giving Project. This year, the department staff collaboratively chose to donate to the Roadrunner Food Bank. Several decorated bins were scattered within the department to allow for easy access for donating non-perishable food items. Ms. Melody Wattenbarger, President and CEO of the Roadrunner Food Bank, was kind enough to send DoIM a lovely "thank you" letter. The letter noted that our donation had a direct impact on their bottom line, reporting a 5% increase of food donated over the last year's total. The department was thrilled with the results of participating in the drive to fight hunger amongst those who are less fortunate within our community.

STAFF APPOINTMENTS IN CENTRAL ADMINISTRATION  Penny Hogan, Program Coordinator/Office of Faculty Development – 07/25/2011  Marisa Sanchez, Sr, Contracts & Grants Administrator/Central Administration (Research) – 10/03/2011  Sara Brown, Admin Assistant III/Central Administration (Education) – 10/07/2011  Shawnee Martinez/Sr. Medical Residency Coord/Central Administration (Education) – 10/17/2011  Lisa Orona, HR Representative/Central Administration (AA/HR) – 11/01/2011  Lisa Sullivan, Admin Assistant III/Central Administration (Education) – 12/12/2011  Rebecca Pena-Ortega, Accountant 3/Central Administration (Finance) – 12/19/2011

STAFF SEPARATIONS IN CENTRAL ADMINISTRATION  Stephanie Michael/Medical HR Representative/Central Administration – 08/25/2011  Patricia Halcli, Admin Assistant III/Central Administration (Education) – 10/07/2011  Penny Hogan, Program Coordinator/Office of Faculty Development – 11/18/2011  Sara Brown, Admin Assistant III/Central Administration (Education) – 12/15/2011

DEPARTMENT OF INTERNAL MEDICINE STAFF AWARDS

Department Chair Professional Staff Department Chair Administrative Staff 1st Place Kate Fox 1st Place Rebecca Chavez 2nd Place Shannon Griego 2nd Place Linda Richardson Nominee Kate Fox and Shannon Griego Nominees Rebecca Chavez and Linda

Richardson

Professional Research Staff 1st Place Armando Sanchez Divisional Administrative Staff 2nd Place Mary Hawkins 1st Place Davina Galbiso Nominee Armando Sanchez and Mary 2nd Place Tina Lujan Hawkins 3rd Place Agatha Santillanes

Nominees Patricia Esquibel, Dina Estrada, Team Award Linda Jeffcoat, Florence Subia, 1st Place Cardiology Team: :Patricia Esquibel, Christie Carroll, Agatha Santillanes, Linda Jeffcoat, Davina Galbiso, Tina Melisssa Cordero, Tina Lujan, and Lujan, David Koepsell Yolanda Hubbard. Nominees Cardiology Team: Patricia Esquibel, Linda Jeffcoat, Davina Galbiso, Tina Divisional Professional Staff Lujan, and David Koepsell. 1st Place Michael Han 2nd Place David Koepsell Gastroenterology Team: Sharon 3rd Place Sharon Castillo Castillo, Dina Estrada, Florence 3rdPlace Pamela Burciaga-Kichner Subia, and Shelby Madrid. Nominee Sharon Castillo, Erika Harding, Pamela Kirchner, Michael Han, and David Koepsell.

OFFICES OF THE VICE CHAIRS OF THE DEPARTMENT

OFFICE OF EDUCATION ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Betty Chang, MDCM, PhD Associate Professor Vice Chair for Education, Department of Internal Medicine

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

GRADUATE MEDICAL EDUCATION  Dr. Michelle Harkins won the Clinician of the Year for the American Thoracic Society.  Dr. Betty Chang has been spending 0.4 FTE in the Graduate Medical Education Office serving as the Acting Associate Dean for Graduate Medical Education and Designated Institutional Official for 3/4 of the academic year.  Dr. Betty Chang has been appointed a Fellow of the American College of Physicians.  The Residency program has appointed a Quality Chief Resident, one of the first in the nation. This Chief Resident will be responsible for quality initiatives in the residency and acting as a liaison between the Department Quality Committee, the Hospital Quality committee and the residency.

UNDERGRADUATE MEDICAL EDUCATION  Dr. Edward Fancovic was named Director for LGBT Equity and Inclusion by the UNMHSC Office of Diversity in September 2011. 0.1 FTE of his time was provided by Dr. Moseley for this HSC-wide effort.

PUBLICATIONS AND OTHER SCHOLARLY ACTIVITY OF THE OFFICE

FACULTY PUBLICATIONS 1. JR Pierce, B Chang, KM Rogers, JJernigan, DR Fotieo, H Kang, RR Leverence. Redesign of an Internal Medicine Ward Rotation for Compliance with ACGME Duty-Hour Restrictions: Operational challenges, education efforts, and professional satisfaction. J of Graduate Medical Education. 4(1), 97-100, March 2012. 2. DP Sklar, B Chang, BD Hoffman. Commentary: Experience with Resident Unions at One Institution and Implications for the Future of Practicing Physicians. Academic Medicine. 86. 552-554, 2011. 3. Arora S, Kalishman S, Dion D, Som D, Thornton K, Bankhurst A, Boyle J, Harkins M, Moseley K, Murata G, Komaramy M, Katzman J, Colleran K, Deming P and Yutzy S. Partnering Urban Academic Medical Centers and Rural Primary Care Clinicians to Provide Complex Chronic Disease Care. Health Affairs (Webfirst 5/19/11), 30:6 June 2011. 4. Harkins, M, Raissy H, Moseley K, Luttecke K, Arora S. Extension of Community Healthcare Outcomes Project-Asthma Specialty Consultation via Telehealth to Improve Asthma Care in Rural New Mexico.: US Respiratory Disease Vol. 7(1):7-9 September 2011. 5. Yaqub S, Harkins MS. A 39 year old female with progressive dyspnea, dry cough and hypoxia: A case report. Southwest J Pulm Crit Care 3:134-40 October 2011.

NATIONAL PRESENTATIONS AND PROFESSIONAL ACTIVITIES BY THE OFFICE

FACULTY PRESENTATIONS  Harkins M, Raissy HH, Moseley K, Luttecke K, Arora S. Project ECHO: Improving Asthma Care in New Mexico with Telehealth Technology. ACCP, October 2011, Hawaii  J. Danaraj, M Harkins. An ominous metabolic disturbance. Presented to Regional ACP meeting Albuquerque October 28, 2011. 1st place award to go to National ACP meeting  Shah JH, Fotieo GG. Structured SMBG with Standard Treatment Improves Glycemic Control in Insulin- Treated Type 2 Diabetics, International Diabetes Federation World Diabetes Congress, Dubai, United Arab Emirates December 4-8, 2011.  Sood A, Seagrave J, Herbert G, Harkins M, Qualls C, Schuyler M. Asthma Is Associated With Lower Adiponectin Concentrations In Sputum Than Controls. Am J Respir Crit Care Med 185;2012:A6502. American Thoracic Society Conference as an oral presentation. San Francisco 2012  Fotieo GG. Does Non-Severe Hypoglycemia Impact the Intensity of Treatment in Patients with Type 2 Diabetes? American Diabetes Association 72nd Scientific Sessions Abstract Book, the June 2012 supplement to the journal Diabetes.  Wendel C, Fotieo GG. Incidence of Non-Severe Hypoglycemia among Veterans in the US: A Prospective Observational Study, American Diabetes Association 72nd Scientific Sessions Abstract Book, the June 2012 supplement to the journal Diabetes.  Wendel C, Fotieo GG. Structured Self-monitoring of Blood Glucose (SMBG) Improves Glycemic Control in Type 2 Diabetic Veterans on Insulin, American Diabetes Association 72nd Scientific Sessions Poster Presentation June 8-12, 2012, the June 2012 supplement to the journal Diabetes.

AWARDS Awards were presented at the annual Spring Awards Banquet to the following residents and faculty. All recipients were chosen by ballot by the residents.

 The House Officer Research Award for 2011-12 was presented to Khaldoon Khirfan, MD.  Intern of the Year: Taylor Goot, MD  Preliminary Intern of the Year: Jason Fredriksen MD  PGY-2 Resident of the Year: Terry Taylor, MD  Resident of the Year: Paul Hassett, DO  Laurent T. Visconti Teaching Fellow of the Year: Jarrod Frizzell, MD  William R. Hardy Teaching Physician of the Year: Sepehr Khashaei, MD  Clerkship Teaching Award: Marc Montanaro, MD

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

 (ACGME) will conduct its first round of annual reports which includes the core Internal Medicine residency program as well as the 10 subspecialty fellowships at UNM.  The residency program will begin to assess the residents on meeting the Milestones as defined by the American Board of Internal Medicine in conjunction with the Association of Program Directors in Internal Medicine. This will be conducted via Direct Observed Encounters.  We will continue to define the role of the Quality Chief Resident as the year progresses

 The Internal Medicine Subspecialty match has moved from the PGY2 year to the PGY3 year. This will necessitate changing our mentoring of resident research timeline, advisement timeline, and schedule requests for residents anticipating entering the subspecialty match.  Dr. Edward Fancovic will be stepping down as clerkship director and Dr. Deepti Rao will be assuming this role.  As a result of the BA/MD students now entering their clinical year, the number of students entering clerkship rotations will increase by 25%. This will necessitate changes in the clerkship structure and resources needed to ensure the education of these learners.

Graduate Medical Education

LEADERSHIP  Betty Chang, M.D.C.M., PhD, Associate Professor, Vice-Chair of Education and Residency Program Director  Gregory Fotieo, M.D., Professor and Associate Director of Residency Program at the Veterans Administration Medical Center  Jennifer Jernigan, M.D., Associate Professor and Associate Director of Residency Program at University Hospital  Dana Fotieo, M.D., Associate Professor and Assistant Director of Residency Program  Michelle Harkins, MD, Associate Professor and Assistant Director of Residency Program

The University of New Mexico’s Department of Internal Medicine Residency Program had a successful recruiting season and match. Six preliminary positions were filled, including 2 from the University of New Mexico. Four Neurology preliminary positions were filled: one from a US school, one from India, one from Jordan, and one from Pakistan. Twenty categorical positions (14 from US Schools and 6 International) were filled, including 3 from UNM. The wide diversity of schools represented includes the Mid-West (U Kansas, U Oklahoma, Creighton U), the Southeast (UT San Antonio, UT Medical Branch in Galveston, U North TX Osteopathic, U Kentucky); the East (Philadelphia Osteopathic, Via Virginia Osteopathic), the West (UNM, U Colorado). International medical schools represented are in India, Japan, Jordan, and Mexico. The wide range of medical schools that supply residents to us continues to enrich the diversity of our program.

Of the 2011-12 graduating class, 7 are slated to practice general internal medicine or as hospitalists (4 in New Mexico), 2 are our own Chief Medical Residents, 1 is our Primary Care Chief Resident, 1 is our Quality Chief Resident and 8 will pursue subspecialty training in various medical subspecialties, 4 at UNM. Of the chief residents, 3 will practice general internal medicine/hospitalist and 1 will pursue subspecialty training. The subspecialty programs chosen by our departing residents include Cardiology (UNM), Gastroenterology (UNM), Hematology/Oncology (UNM), Nephrology (Tulane U, U Utah), and Pulmonary/Critical Care (U Louisville, Iowa U).

Our graduates have a cumulative pass rate of 79% for the ABIM certifying exam for 2009 through 2011. For the 2011 graduating class we have a ABIM pass rate of 86%.

We successfully received a 5-year accreditation from the ACGME with only one citation. Our one citation was an ABIM board pass rate below the 80% requirement. Because of this citation, we were not given our program expansion from 74 to 79 residents. However, we have been given a temporary expansion of 2 residents for 2 years pending an improving rolling average ABIM pass rate.

International electives, both clinical and research rotations, were provided for two residents in Ecuador and Kenya.

An annual survey of all residents was again conducted. The information gathered will be used to improve the program. Of particular concern were duty hours at the VA inpatient rotation.

The program continued to use the TSheets software to enter duty hours. Duty hour entry compliance is excellent. The software allows real time monitoring of duty hours and has greatly reduced violations.

The Office of Education continues to track compliance on a daily basis and follow up on the causes of any suspected violations. Weekly duty hour reports are being sent to the GME office, head hospitalists, involved faculty, and Dr. Moseley for review.

With the assistance of the faculty at both institutions, 30-hour violations are virtually nonexistant. There have been no 80-hour violations since adopting our new duty hour policy. We hope to be in good shape for the new duty hour requirements effective July 2011

Wards at UNMH changes based on new duty hour requirements: post night call interns are excused before 11am or 12 if it is a two-intern team.

Wards at VA changes to meet new duty hour requirements: The interns are split between a day and night call shift.

Cardiology at UNM made changes to meet the new Duty hour requirements by decreasing to 24+4 call through the majority of the academic year. In June of 2012, they moved to a shift base schedule eliminating all 24 hour call. This is a nested night float model similar to that used in the MICU for the last year with success.

MICU changes to meet the new duty hour requirements: The interns and residents will change to a nested night float model where each intern-resident pair will do 7 nights.

Thursday School continues to be a success in terms of gathering 60% of the residents for committed didactic time free from clinical duties.

We successfully were able to move Thursday School didactics to the BBRP 1500 enabling more residents to attend conference.

To teach professionalism within the profession of medicine, we instituted professionalism morning report where cases of professionalism or non-professionalism are discussed. Our goal is to better define the “gray” zone of professionalism and professionalism expectation.

The House Officer Scholarly Activity Committee continued to be successful under the direction of chair Michelle Harkins, MD. Potential mentors and research projects were identified. Assistance was provided to residents in connecting with a suitable mentor for their interests.

House officers continued to be productive in their research and scholarly activities.

Resident Portfolios continue to be maintained in the Office of Education and provide a road map of the resident’s residency experience.

Evaluations of residents by faculty have been closely monitored and the completion rate has improved to greater than 97%.

For faculty annual reviews, the Office of Education sends summary reports of faculty evaluations are sent to Division/Section Chairs when requested.

The Office of Education sends summary reports of rotations to all rotation directors annually.

The program continues to work upon improving the practice based learning and improvement/quality improvement projects in the outpatient setting.

PUBLICATIONS BY INTERNAL MEDICINE RESIDENTS 2011-2012 1. Al-Sadi R, Khatib K, Guo S, Ye D, Youssef M, and Ma T: Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier. Am J Physiol Gastrointest Liver Physiol 300: G1054-G1064, March 2011. 2. Ass’ad N, Sood A: Leptin, adiponectin and pulmonary diseases. Biochimie PMID: 22445899, March 14, 2012 [EPub ahead of print]. 3. Michel Barakat; Nazem Akoum; Nathan Burgon; Thom Haslam; Kavitha Damal; Nassir Marrouche. Comprehensive Arrhythmia Rsch and Management Cntr, Univ of Utah, Salt Lake City, UT. Circulation. 2011; 124: A14088. 4. Yaqub S, Harkins MS. A 39 year old female with progressive dyspnea, dry cough and hypoxia: A case report. Southwest J Pulm Crit Care 3:134-40 October 2011. 5. Scullin CS, Tafoya, LC, Wilson, MC: Presynaptic residual calcium and synaptic facilitation at hippocampal synapses of mice with altered expression of SNAP-25. Brain Research, accepted 10/20/2011.

RESIDENT ABSTRACTS/PRESENTATIONS AT REGIONAL AND NATIONAL MEETINGS 1. Ponce, Sonia: Beaded necklace-like image observed by real-time three-dimensional transesophageal echocardiography as evidence of bacterial vegetations in a dialysis catheter. Oral presentation at Carmel Western Regional Meeting, January 2012. 2. Khirfan, K, Byrd W, Boedeker E. Orogastric zinc decreases intestinal inflammation in Shiga toxin producing E. coli infection. Abstract at Carmel Western Regional Meeting, January 2012. 3. Brittain P, Kelly S, Garcia D. Defining venous thromboembolism in patient with cancer. Abstract at Carmel Western Regional Meeting, January 2012. 4. Colombo, E. Sage: Poster: Alterations in Neural Telomere System Following Chronic Inhalation Exposure to Coal Combustion. Society of Toxicology meeting in San Francisco, CA, March 13, 2012. 5. Khirfan K: Orogastric administration of zinc (Zn) decreases intestinal inflammation in shiga toxin producing E. coli (STEC) infection. Presented at Digestive Disease Week, San Diego, CA, May 2012. Travel Award Winner 6. N. Assad, C. Qualls, L. J. Smith, A. Arynchyn, B. Thyagarajan, D. Jacobs, A. Sood. BMI-defined obesity is a stronger predictor than metabolic syndrome for future asthma risk on women- The CARDIA study. Oral presentation, presented at a mini-symposium: How do dietary factors and obesity influence lung diseases? ATS international conference May 2012. San Francisco, CA. 7. Michel Barakat: Abstract 14088: Advanced Chronic Kidney Disease Is Associated With Increased LGE-MRI Quantified Atrial Fibrosis in Patients with Atrial Fibrillation. Presented at National Cardiology meeting May 2012. AHA. 8. Libby E, Quintana D, Garcia D, Bauman J, Fekrazad H, Hromas R, Rabinowitz I, Ebaid A, and Wiggins C. Using population-based cancer surveillance and vital records to document improved outcomes for multiple myeloma. N American Asso Central Cancer Registries – Annual Meeting, Portland, OR, June 2012.

9. Khirfan K, Byrd W, Wilbur JS, Vedantam G, Boedeker EC: Deletion of a single secreted virulence protein (EspZ) eliminates the inflammatory cytokine response to rabbit enteropathogenic Escherichia Coli infection. Presented at Digestive Disease Week, San Diego, CA, May 2012. 10. J. Danaraj, M Harkins. An ominous metabolic disturbance. April 2012. American College of Physicians, New Orleans, Louisianna.

CLINICAL VIGNETTES PRESENTED AT NEW MEXICO ACP MEETING, OCTOBER 2011 1. Nada Bader, MD. “Eosinophilic Ascites in a Previously Healthy Female” 2. Khaldoon Khirfan, MD. “Hyper and Hypoglycemia; Manifestations of the same Pathology” 3. Jonathan Danaraj, MD. “Lymphoma induced lactic acidosis and Hypoglycemia - An ominous metabolic disturbance.” 1st place award to go to National ACP meeting 4. Romy Cabacungan, MD. “Pleural Fluid Cytology; An Alternate Diagnostic Approach for Catamenial Pneumothorax.” 5. Mariam Salas, MD. “The Obscure but Destructive Mycobacterium Abscessus.”

POSTERS PRESENTED AT NEW MEXICO ACP MEETING, OCTOBER 2011 1. Orwah Al-Khalili, MD: “A case of newly diagnosed adult still’s disease on top of anti-TNF treatment” 2. Prajit Arora, MD: “An unusual infectious cause of diabetic etoacidosis” 3. Nour Ass’ad, MD: “Acute lung injury induced by CAL-101; an investigational PI3 Kinase delta inhibitor” 4. Deepthi Byreddy, MD: “Chronic pain: using a more comprehensive approach for treatment” 5. Rory Carrera, MD: “A Case of Mistaken Identity” 6. Jeffery Edwards, MD: “ Atypical Presentation of Wegener’s Granulomatosis” 7. Khaldoon Khirfan, MD: “A Crisis In The Intestine” 8. Khaldoon Khirfan, MD: “Glioblastoma Multiforme in a patient treated with Cladribine for Hairy Cell Leukemia” 9. Emily Newsom, MD: “A Difficult Case of Ichthyosis” 10. Sonia Ponce, MD: “Beaded Necklace-Like Image Observed By Real-Time Three-Dimensional Transesophageal Echocardiograhy as Evidence of Bacterial Vegetations In A Dialysis Catheter”

Undergraduate Medical Education

LEADERSHIP  Edward Fancovic, M.D. Professor, Clerkship and UNM Director  Deepti Rao, M.D. Assistant Professor, Sub-I Director  Teodora Konstantinova, M.D. Assistant Professor, UME Site director at the VA

Phase I teaching activity in lectures and tutorials is now being tracked by the Vice-Chair for Faculty Development.

The phase II clerkship underwent significant structural changes with the beginning of the new phase II year in April 2012. This has required changes in scheduling and in assessment of students.

From July 2011-April 2012, the 8-week rotation was entirely inpatient-based, with students doing 4 weeks at University Hospital (UH) and 4 weeks at the VA. Students met twice with clerkship faculty for assessment and feedback using the PRIME grading system, once with Drs. Fancovic/Rao at UH and once with Dr. Konstantinov at the VA. Evaluations were obtained from attendings and residents working on the same teams as the students, and were summarized and graded by clerkship faculty.

Beginning in April 2012, an ambulatory block was introduced to the clerkship for the first time in nearly 20 years. All students now complete four weeks of inpatient service at UH, 2 weeks of inpatient at the VA, and two weeks of ambulatory clinics at the VA. This serves several purposes:

 Accommodation of the 25% increase in class size, with the entry of the first cohort of BA/MD students into the phase II cycle this year, without overloading the inpatient teams.  Providing students with exposure to ambulatory care, and providing outpatient faculty the opportunity for role modeling to students at their most impressionable time.  Providing students with more exposure to medical subspecialty care, which enhances their experience with the breadth of internal medicine both from a curricular aspect as well as from a career-planning aspect.

Providing students with additional down time for self-directed learning and study during the less time-intensive ambulatory rotation, which has been repeatedly cited as a need on student evaluations of the clerkship over several years.

Assessment of student performance on their inpatient rotations remains the same, using the PRIME format and meeting with clerkship faculty near the end of each inpatient block. The ambulatory block faculty are asked to perform daily performance evaluations using the Mini-CEX forms developed by the ABIM, which are collated and graded by the clerkship director at the end of the block.

Other graded aspects of the clerkship include tutorial and the Post-Discharge Home Experience. The structure of tutorial continues to evolve. From July 2011-April 2012, there were weekly meetings of tutorial groups led by teaching faculty, with small-group discussions of structured online cases in internal medicine (the SIMPLE cases: Simulated Internal Medicine Patient Learning Experience). Students were also required to do 5 additional online cases as self-study exercise and received a pass/fail grade.

Beginning in April 2012, the weekly small-group case discussions continued, but the self-study portion was changed to allow contract grading, with the overall grade depending on the number of successfully completed cases. This was implemented to further the students' learning of additional curricular topics beyond what they may encounter on inpatient ward rotations, as the 36 available SIMPLE cases are designed to cover the core clerkship curriculum objectives developed by the Clerkship Directors in Internal Medicine, a national group of clerkship educators.

The Post-Discharge Home Experience completed its second clerkship year and continues in 2012-13 under the direction of Dr. Cindy Arndell. It meets several curricular goals outlined by the UNMSOM Curriculum Committee as cross-cutting issues: it provides an introduction into systems-based practice, examines transitions of care, and is an opportunity for interprofessional education and collaboration. Two medical students identify a patient during a UH inpatient admission under their care and then make a home visit to this patient within a week after discharge, accompanied by a doctoral-level pharmacy student. They also collaborate with team social workers, nurse case managers, and physical/occupational therapy services prior to discharge to get information about the patient's functional status, literacy level and social support, as well as reviewing their discharge medications and appointments. At the home visit, the students reevaluate the adequacy of the discharge planning, reassess the home environment, and the pharmacy students perform a detailed medical reconciliation and note discrepancies. Students then present their findings in written form to the patients' primary care providers, and orally at a debriefing session with ambulatory faculty, inpatient faculty, pharmacy faculty and case managers. They receive a passing grade contingent upon their successful completion of these requirements. The experience has often been

21 a very rich one for the students, who learn when, how and how often things can go wrong with transitions of care, and can make a significant difference for individual patients when plans go awry.

Other teaching activities within the clerkship include:

 Weekly lectures by various faculty  Weekly ECG classes during the VA/ambulatory blocks by Dr. Lori Serkland and Dr. Dara Lee  Monthly CXR classes with Dr. Loren Ketai of Radiology at UH  Monthly discussions of death and dying with Dr. Judith Kitzes, Dr. Devon Neale and Dr. Esme Finley of the UH Palliative Care service.  Monthly discussions of ethics issues with Dr. Aroop Mangalik.

Clerkship faculty also continue to maintain active involvement in multiple SOM educational committees, including Admissions (Dr. Fancovic), Clerkship Directors (Drs. Fancovic and Rao), Curriculum (Dr. Fancovic), and Student Performance and Evaluation (Dr. Fancovic in 2011, Dr. Konstantinova in 2012).

PHASE III STUDENTS: Curriculum Updates Dr. Deepti Rao continued with the subintern curriculum she instituted in 2009-2010. She is working with other subinternship directors at the SOM level to standardize objectives for this rotation across disciplines. The curriculum includes BatCave interactive simulation teaching experiences including hands on procedural instruction, as well as lectures on common topics and communication issues.

PRIME sessions have been added for the Phase 3 students in order to provide feedback midway through their rotation.

Dr. Arndell continued in her role as DoIM Director of the Phase 3 Comprehensive Ambulatory Medicine rotation

The MICU rotation at the VAMC remains unavailable until additional permanent faculty are hired to staff the service.

Match results: there has been a steady rise in the number of students matching in internal medicine over the past 3 years:

 Class of 2010: 3 categorical  Class of 2011: 6 categorical + 1 med/peds  Class of 2012: 10 categorical + 1 med/peds

OFFICE OF FACULTY DEVELOPMENT

ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

J. Rush Pierce, Jr., MD, MPH Associate Professor Vice Chair for Faculty Development, Department of Internal Medicine

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

When Dr. Bronwyn Wilson was appointed Associate Dean for Academic Affairs with the School of Medicine on January 1, 2012, Dr. Moseley appointed Dr. Rush Pierce to replace her as the Department’s Vice-Chair for Faculty Development. Dr. Pierce had joined the Division of Hospital Medicine in 2009, where he serves as Director of Research and Scholarly Activity.

PROMOTION & TENURE  Eleven members of the Department were promoted in 2012, six to the rank of Professor.  The Department formalized promotion criteria for clinician-educators, including a 3-year phased-in implementation of requirements for products that demonstrate dissemination of scholarship.  The Office conducted a study of promotion rates within the Department from 2009 – 2012. This study demonstrated no difference in promotion rates by gender, rank, part-time vs. full-time employment, or for faculty on the clinician-educator vs. tenure track. Department promotion rate of eligible faculty declined from 41% in 2009 to 29% in 2012.

CAREER DEVELOPMENT  The Division of Hospital Medicine’s monthly Research Club for clinician-educators was expanded to include clinician-educators in other Divisions. The goal of this lunch gathering is to provide an informal forum for junior clinician-educators to exchange ideas and discuss their scholarly activity with other clinician-educators.  The Department initiated a junior faculty exchange program with two nearby medical schools (the University of Colorado School of Medicine and Texas Tech University School of Medicine). The program will be piloted in the Hospitalist Division. Targets of this program are mid-career faculty. Goals of the program include (a) assisting individual faculty promotion by gaining reputation outside of home institutions; (b) development of external mentorship and career advice relationships for junior faculty; and (c) enhancing intra-institutional networking and project collaborations. The first visiting faculty are scheduled to visit this fall.  Dr. Pierce participated in the Division of General Internal Medicine’s annual retreat and discussed promotion criterion and career development for clinician-educators.

PROFESSIONALISM Two of our Internal Medicine residents developed a resident-led case-based professionalism curriculum. Once per month instead of our usual morning report, one resident chose one or two of the resident-written cases and led a discussion with residents and students. Cases discussing respect for patients and appropriate use of social media were especially popular. An abstract of this curriculum was presented at the 2012 Society of Hospital Medicine Annual Session and chosen as one of the top 5 innovations in 2012.

FACULTY EFFORT IN EDUCATION With major assistance from Kate Fox, the Office developed and implemented an internet-based reporting system whereby Department faculty could record their educational, research mentorship, and community outreach activities. This system has greatly facilitated the Department in its efforts to compensate Divisions for educational activity of their faculty and to provide positive economic incentives for medical student education and research mentorship. This system also transfers data electronically to the School of Medicine Faculty Activity Database (FAD), which has improved timeliness, enhanced completeness of data capture, and led to significant reduction in effort related to School of Medicine FAD reporting.

MENTORSHIP A road map for promotion was developed for the Division of Hospital Medicine, and has been shared with the Division of General Internal Medicine. Guidelines and a checklist for mentors to assist with this process were developed.

DEPARTMENTAL AWARDS Dr. Sepher Khashaei was awarded the 2012 William R Hardy Teaching Physician of the Year, and Dr. Milton Icenogle the 2012 Robert G Strickland Distinguished Service Award.

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

PROMOTION & TENURE

 Monitor promotion rates to assess effects of more strict promotion criteria for clinician-educators  Post informational material related to promotion and tenure on Department website  Develop Department guidelines and a standardized process for appointment of volunteer faculty

CAREER DEVELOPMENT  Implement monthly faculty development luncheon for new faculty  Expand Research Club for clinician-educators  Post career development material on Department website  Create a database of faculty research and scholarly interests

PROFESSIONALISM  Develop Department newsletter  Develop professionalism goals within the Department

FACULTY EFFORT IN EDUCATION  Develop training module for the on-line FAD  Analyze Department educational, research mentoring, and community outreach activities

MENTORSHIP  Create and maintain an database of mentors and protégés in the Department  Develop guidelines for defining mentorship within the Department  Evaluate Departmental mentorship  Develop Mentor training programs

APPOINTMENTS

FACULTY Name Title Effective date J Rush Pierce Jr, MD, MPH Associate Professor January 1, 2012

STAFF

None

SEPARATIONS

FACULTY Name Title Effective date Bronwyn Wilson, MD Professor Dec. 31, 2011

STAFF Name Title Effective date Penny Hogan Nov. 18, 2011

PUBLICATIONS AND OTHER SCHOLARLY ACTIVITY OF THE OFFICE

1. Eder M, Pierce JR Jr. Empowering busy clinical faculty to conduct and publish research: development of a research assistance unit (RAU) at a regional medical school campus. South Med J 2011;104(9):647-650. 2. Pierce JR Jr, Chang B, Rogers KM, Jernigan JR, Fotieo DR, Kang H, Leverence RR. Redesign of an internal medicine ward rotation: operational challenges and outcomes. J Grad Med Educ 2012;4:97-100.

NATIONAL PRESENTATIONS AND PROFESSIONAL ACTIVITIES BY THE OFFICE

1. Menon R, Garcia P, Rogers K. Plugging gaps in professionalism education: a resident-generated curriculum. Society of Hospital Medicine, 04/02/2012, San Diego, CA. J Hosp Med 2012;7(Suppl 2):S7.

OFFICE OF QUALITY, SAFETY & CLINICAL OPERATIONS

ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Richard Crowell, MD Professor Senior Vice Chair for Quality, Safety & Clinical Operations, Department of Internal Medicine

 Lee K. Brown, MD; Vice Chair for Clinical Operations  Julie Broyles, MD; Patient Safety Officer; Medical Director, Credentialing  Leonard Noronha, MD; Assoc. Medical Director, Clinical Operations  Diane M. Dodendorf, MS, PhD; Quality Manager

MISSION STATEMENT The mission of the Office of Quality, Safety, and Clinical Operations is to establish the UNM Department of Internal Medicine as a national leader in academic medicine for providing proficient, evidence-based care to our patients at the highest levels of quality and safety.

GOALS/OBJECTIVES  Identify Quality and Safety concerns that impact patient care provided by the DoIM, then develop and implement programs for improvement  Develop efficient measurement tools and reporting mechanisms to support improvement objectives developed by the MQG  Provide leadership in the UNM Health System for improving the quality and safety of patient care through collaborations with Quality and Safety programs at UNMMG and UNMH.

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

IMPLEMENTATION OF MEDICINE QUALITY GROUP (MQG)  Monthly meetings of members from DoIM, UNMMG, and UH  Coordinate various Quality efforts within the DoIM with development of infrastructure, identification of resources, both inpatient and outpatient focus  Further development of ongoing collaborative relationship with UNMMG and UH, with focus on aligment of Quality and Safety strategies within the UNM Health System

MORTALITY REVIEW  All DoIM inpatient deaths reviewed by DoIM faculty  Development of web-based review process for providers  Streamlining of review process, decreased in turnaround time from death to completion of review process to < 1 week  Incorporation of secondary reviews into database, feedback  Incorporation of all Patient Safety Network (PSN) reports of patient deaths into review process, monthly reviews, and patient database  Develop capabilities for active identification of system issues

INTEGRATION OF DoIM QUALITY MANAGER INTO QSCO ACTIVITIES  Data management and reports for Cardiology “Get With the Guidelines” project  Developed approaches for measuring transitions of care for heart failure patients  Set up clinical alert system for identifying heart failure patients that qualify for GWTG  Assists with data collection, processing, management for Sepsis Mortality Improvement Team (SMITe)  ED to MICU project: initial data management, analysis  Support for ongoing Quality Research projects and reports  Development of ICU quality checklist database, iPad-based system for data collection  Development of heart failure medicine reconciliation checklist database for 7South, iPad-based system for collection  Development of collaborative relationships with UNMMG, UH committees and data centers

QUALITY/SAFETY-SPECIFIC EDUCATIONAL ACTIVITIES  Grand Rounds, Executive Committee reports, Divisional meetings, Internal Medicine Residency Thursday School

RESEARCH / COMPARATIVE EFFECTIVEMENT ACTIVITIES  Variables associated with increased sepsis mortality risk in patients with cirrhosis (C. Quintana, MD)  Effect of increased fluid volume resuscitation to higher CVP levels in patients with severe sepsis (S. Hayatdavoudi, MD)  Mortality effects of the timing of initial antibiotics during Early Goal-Directed Therapy of severe sepsis in Emergency Department patients admitted to the MICU: the UNM experience (R. Crowell, MD; J. Femling, MD; W. Demaray).

RISK MANAGEMENT / PATIENT VULNERABILITY  Strengthened ongoing relationship with Risk Management groups in UH and SOM  Identify risk issues, address intermittent risk and vulnerability problems as the arise

CREDENTIALING  Refined Credentialing / re-credentialing process  Incorporate OPPE into ongoing credentialing, and optimize the use of information obtained into ongoing provider evaluation processes within the DoIM

QSCO – CLINICAL OPERATIONS

DOIM BUSINESS OFFICE  Billing, charge capture  Monitor productivity, collections  Provide feedback: Monthly metrics, Specific Division or provider feedback (Monthly, Special requests)  Optimize the charge capture of the process  Evaluate billing/coding patterns, charge capture processes : Provide feedback for improvement (provider, Division levels) ; Educational activities (Individual providers, Divisions), (Fellows, resident documentation training

 New process for patient list submission was identified as best practice and implemented for Hospitalist Medicine.  Noronha, Dronet Poster: WHAT ROLE SHOULD HOSPITALISTS PLAY IN PROVIDER BILLING? was accepted as a finalist for the poster competition in the innovations category at the Society of Hospital Medicine's Annual Meeting  Coding & Documentation training – Divisions, Individual Faculty, Fellows, Residents  Creation of UNM DoIM Specialty Dictation Templates  Clinical Metric presentations by Division  Presentation of Department clinical metrics at DoIM Executive Committee meeting  Individual Provider Productivity reports distributed to all providers on a quarterly basis  Quarterly Procedure Reports distributed to all providers  Ongoing assessment of Provider productivity  Ongoing monitoring of revenue and wRVUs  58% increase in collections over past 5 years  6% increase in collections from FY11-FY12  40% increase in wRVUs over past 5 years  4% increase in wRVUs from FY11-12  Development of Sleep center expansion pro-forma

CLINICAL PRACTICE Outpatient care issues on 5-ACC  Applied for additional staff to facilitate transition to “single specialty group practice” model in separate pods  Move of General Medical Clinic to Southwest Mesa facility completed, adding additional space for medical specialties  Completed LEAN sessions to analyze and reorganize front-office operations  Applied for capital renovation funds to move registration and telephone operations to atrium and create added examination, triage, and discharge spaces

Clinics Offsite  Concept approved for combined research and clinic building funded by DCI and negotiations/approvals ongoing  Negotiations held to transition West side Allergy clinic to UNMMG  Plans completed for move of Truman Street Clinic to new location

Ease of Practice Physician Advisory Group “Effective Model(s) to Empower Medical Directors Work Group. Final report forwarded to UNMMG Board of Directors for action.

 Query “best practice” staffing and management models of other academic practices, private single- specialty group practices, and UNMMG clinics: no action taken  Develop management education opportunities for medical directors: UNM Medical Leadership Academy created  Develop more effective reward system for staff productivity that aligns with unit director/medical director goals

Shared Decision-making Task Force (SOM Faculty and UNMH managers)  Unit director/medical director collaboration on all management decisions including budget; shared goals: in effect for many clinical units  Extend collaborative management to more senior levels: dyads created or identified  Mutual access to UNMH and SOM/UNMMG IT Systems including budgeting, evaluations, and hiring: no action taken by UH as yet

Sandoval Regional Medical Center  Development of inpatient care model including role of internal medicine specialty physicians  Recruitment of hospitalists (including Section Chief) and subspecialty faculty  Develop outpatient specialty practices: Medical Office Building; 528 and Southern  Continued support in recruitment and development of primary and specialty care faculty positions for planned Primary Care staffing needs and at the Sandoval Regional Medical Center.  Pro-forma submitted for SRMC-based Sleep Center

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

MEDICINE QUALITY GROUP (MQG)  Expand UH alignment activities o Further UH committee involvement of DoIM QSCO representatives o Integrate DoIM QSCO into Strategic Planning Goals for UNM Health System

MORTALITY REVIEW  Revise Departmental and Divisional M&M conferences to reflect system-based approaches to address adverse events

PROCESS REVIEWS Initiate process reviews for major adverse events for DoIM procedures, both inpatient and outpatient.

 Review all processes for identifying, documenting, measuring, and review of procedures performed by DoIM personnel

QUALITY/SAFETY-SPECIFIC EDUCATIONAL ACTIVITIES  Expansion educational activities, with focus on residency and fellowship training  Development of Quality Chief Residency position, with specific responsibilities of: o Develop and provide educational support for individual resident outpatient quality projects o Act as liaison with Intermal Medicine residency and fellowship programs for DoIM Quality and Safety activities o Develop collaborations with UH Nursing units on which DoIM residents work, focused on ongoing Nursing Quality and Safety initiatives and programs o Develop and complete research project in Quality and Safety and for presentation and publication  Coordinate and co-manage in depth Quality Seminar series for residents and fellows at UNM School of Medicine o Align and co-manage seminar series with Office of Quality and Safety, University Hospital

RESEARCH / COMPARATIVE EFFECTIVEMENT ACTIVITIES  Expand processes to facilitate Research, Quality Improvement, and Comparative Effectiveness projects for residents and fellows

CREDENTIALING  Participate and lead in UH-wide revision of credentialing guideleines, format, processes

QSCO – CLINICAL OPERATIONS

DOIM BUSINESS OFFICE  Ongoing assessment of Provider productivity  Ongoing monitoring of revenue and wRVUs  Continued collaboration with UNMMG coding staff to increase individual Provider education  Continued reporting of clinical metrics  Develop RFP for Departmental Travel Clinic

CLINICAL PRACTICE Outpatient care issues on 5-ACC  Diabetes Comprehensive Care Center to be moved to 5-ACC  Add additional services to Diabetes Comprehensive Care Center  Obtain communication devices to allow real-time coordination of staff activities  Recruit the additional 2 approved staff FTE’s  Initiate renovation planning using the small amount of funds allocated  Analyze provider templates to increase room utilization

Offsite Clinics  Pulmonary Hypertension Clinic to be initiated at 1101-4 Medical Arts NE  Participate in planning for Nephrology’s research and clinic building  Transition West side Allergy Clinic to UNMMG  Move Truman Street Clinic to new location  Publish RFP for Travel Medicine Services and award to best proposal  Continue planning for Geriatrics participation in Rio Rancho assisted care facility  Consolidate and move Cardiology and Pulmonary Hypertension services to Cardiovascular Center

Ease of practice  Await UNMMG Board of Directors action on proposals  Translate ACCESS database at Sleep Disorders Center into cloud-based Oracle/Cold Fusion application  Sleep Laboratory staff to initiate LEAN process  Advocate for improved integration of mid-levels with clinical units

Shared Decision-making Task Force (SOM Faculty and UNMH managers)  Await resumption of activities

After-hours Patient Calls Task Force- Plan for system-wide answering service  Pro-forma to be developed for in-house answering service for presentation to senior leadership

Sandoval Regional Medical Center  Fine-tuning of inpatient care model including role of internal medicine specialty physicians  Develop outpatient specialty practices: Medical Office Building; 528 and Southern  Continued support in recruitment and development of specialty care faculty positions as requested, including GI and Nephrology  Develop SRMC Sleep Disorders Center and integrate with the UNM-HSC Program in Sleep Medicine

APPOINTMENTS

FACULTY None

STAFF Name Title Effective date Diane Dodendorf, PhD Quality Manager 9/1/2011

SEPARATIONS

FACULTY Name Title Effective date Leonard Noronha, MD Assistant Medical Director, Clinical Ops 6/30/2012

STAFF None

NATIONAL PRESENTATIONS AND PROFESSIONAL ACTIVITIES BY THE OFFICE

1. University Healthcare Consortium, "IQ Mortality Sepsis Management Member Spotlight: Reducing Sepsis Mortality". Web Conference for the University HealthSystem Consortium, Imperative for Quality Program. 2. Grand Rounds, “Reducing Sepsis Mortality at UNMH”. Presbyterian Healthcare Services, Albuquerque NM. 3. Noronha L, Dronet A. What Role should Hospitalists play in Provider Billing?" Presented at Society for Hospital Medicine Annual Conference, April, 2012.

OFFICE OF RESEARCH

ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

David S. Schade, MD Professor Vice Chair for Research, Department of Internal Medicine

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

The Department of Internal Medicine’s Office of Research supports and encourages faculty and with their sponsored project endeavors, and strives to foster an environment which will enhance research activity and strengthen the competiveness of the School of Medicine in securing external funding.

KEY ACCOMPLISHMENTS IN FY 2012  Blueridge Institute for Medical Research (BRIMR), in its annual report of rankings for NIH funding to medical schools in the United States, ranked the University of New Mexico- School of Medicine 69 out of 138 in 2011.  BRIMR reports that total NIH funding for the University of New Mexico School of Medicine was $45,325,093. Of this amount, the Department of Internal Medicine received $6,119,628, comprising 13.5% of the funding.

PROPOSALS  Throughout the UNM-Health Science Center, 60 Internal Medicine faculty members submitted 243 proposals requesting $54,089,178 in external funding. Submissions were made directly through Internal Medicine, as well as through the Cancer Research and Treatment Center, the CRTC New Mexico Tumor Registry, Center for Infectious Disease and Immunity, the Clinical and Translational Science Center, and the SOM Dean’s Office.  150 of these proposals, totaling $34,207,325, were submitted directly through Internal Medicine.

AWARDS  Throughout the UNM-Health Science Center, 54 Internal Medicine faculty members received 168 awards totaling $31,574,914. Awards were made directly to Internal Medicine, as well as through the Cancer Research and Treatment Center, the CRTC New Mexico Tumor Registry, Center for Infectious Disease and Immunity, the Clinical and Translational Science Center, and the SOM Dean’s Office.  106 of these awards, totaling $16,857,611 were awarded directly through the Department of Internal Medicine.

FUNDING ATTRIBUTES  Among the awards, DOIM received funding for 30 new Clinical Trials and 31 subawards.  Federal Funding continues to be the principal source of extramural awards, comprising approximately 72% of all funding through direct awards and pass-through subawards. State funds comprised 16% and private/industrial funds accounted for approximately 12% of all new awards.  NIH funded 35 awards directly to DOIM faculty and the large majority of subawards received were also NIH pass-throughs.

Proposals Submitted & Awards Received by Type of Funding Agency (Submissions by DOIM Faculty throughout UNM HSC) FY 2011 70 60 Proposals Awards 50

0 Pharmaceutical & NIH Subawards Other Federal State & Local Foundations & Industry Sponsors Agencies Government Professional Agencies Associations

DOIM FACULTY WITH VA APPOINTMENTS  DoIM Faculty with joint Veteran’s Administration appointments received an approximate $2,051.456 in new awards, with the majority of funds coming in the form of “Merit Grants” funded by the VA itself. Nine proposals were submitted through BRINM totaling $5,526,469. Among the awards was a $40,000 PCORI grant awarded to Dr. Toru Nyunoya for smoke-induced Emphysema research.

TRAVEL FUNDS  The DOIM Office of Research provided $11,000 to support travel by 11 fellows and residents presenting abstracts at national and regional meetings.  Five fellows traveled to present at the AFMR Western Division meetings at Carmel, CA in January 2012, 2 traveled to the Chest 2012 Annual Conference in Honolulu, Hawaii, and DOIM was also represented by fellows attending The Society of General Internal Medicine (SGIM) Annual Meeting in Orlando, Florida, the ARVO’s Annual Meeting in Fort Lauderdale, Florida, Digestive Disease Week Conference in San Diego, CA, and the SLEEP 2012 Conference in Boston, Massachusetts.

OTHER RESEARCH PROGRAMS Research requires financial resources. In most cases, this means available funds for investigators to acquire sufficient pilot data to successfully apply for peer reviewed funding. These funds can vary from small amounts for such items as “publication costs” to larger, more costly items such as technical help or major equipment. To this end, the DoIM has initiated (in cooperation with the HSC) funding programs to support both junior investigators and experienced, research funded faculty.

SMALL GRANTS FOR RESEARCH  DoIM’s-Office of Research manages a small grants program available to all DoIM faculty. It provides awards up to $500 for miscellaneous research items necessary to complete projects, support medical student and resident projects, and pay for publication costs. A rapid approval process assures timely funding for all investigators.  In FY 2012 the Office of Research provided 2 grants for $500 each to Dr. Akshay Sood and Dr. Michelle Harkins to facilitate their students’ presentations at national conferences.

RESEARCH ALLOCATION COMMITTEE (RAC) GRANTS The primary mission of the HSC RAC fund is to support the career development of junior faculty at UNM who are in the early stages of career development and initially establishing their first research programs. Secondary goals are to cover emergency needs between periods of extramural funding (bridge funding) and to fund developmental projects/pilot project initiated by any faculty (junior or senior).

 Kristina Flores, Pulmonary was awarded a RAC Grant: 3/1/2011 - 2/29/2012, $24,229, entitled, “Gene Methylation Patterns in Malignant Melanoma.”

SPACE In FY 2012- DOIM acquired approximately 11,379 square feet of new space in the following areas:

In the TriServices Building  2000 sq ft -2nd Floor; With the initiation of the new Translational Informatics division in the DoIM, space was needed to house the multiple servers and computers which are required for their research studies. This space is ideal as it had been recently renovated with appropriate wiring and cooling for electronic equipment.  4895 sq ft-3rd Floor; this space includes approximately equal amounts of wet and dry research space. It is anticipated that this space will be available for occupancy by investigators in the summer of 2012. Specific plans to recruit additional basic and clinical researchers in the area of gastroenterology is being spear-headed by Dr. Thomas Ma, chief of the GI division.

ACC 4th Floor  1400 sq ft which will provide 12 new offices for DoIM faculty. The intention is to recruit new faculty to the DoIM with peer reviewed research funding.

The Department as a whole, through the Office of Research, began to collaboratively utilize the FAMIS Space Database, to comprehensively track all DOIM space, including wet and dry lab space.

APPOINTMENTS

FACULTY None

STAFF Marisa Sanchez Sr. Contract & Grant Administrator October 3, 2011

SEPARATIONS

FACULTY None

STAFF None

UNM HSC- DEPARTMENT OF INTERNAL MEDICINE US NON-PROVISIONAL US PATENTS FILED

FY 2012- Year to Date

INVENTOR INTELLECTUAL PROPERTY TITLE PATENT PATENT PATENT TRACK CODE APPLICATION APPLICATION PROVISIONAL # DATE Hromas, Robert Metnase and Intnase Inhibitors and their Use in 13/255,708 9/9/2011 2009-121-05 Williamson, Elizabeth Treating Cancer Wray, Justin W Boedeker, Edgar Attenuated Enterohemorrhagic E coli based 13/378,116 12/14/2011 2009-025-03 Byrd, Wyatt Vaccine Vector And Methods Relating Thereto

Bauman, Julie Method for Treating Infection by HPV 13/455,665 4/25/2012 2011-061-03

Murata, Glen System and Methods for Estimating HBA1C, 13/505,103 4/30/2012 2010-104-03 Treatment Response, and Hypoglycemia Risk Using Self-Monitoring of Blood Glucose Data

UNM HSC- DEPARTMENT OF INTERNAL MEDICINE ISSUED PATENTS

FY 2012- Year to Date

PATENT INVENTOR INTELLECTUAL ISSUE DATE INTELLECTUAL PROPERTY TITLE PATENT PATENT PROPERTY # APPLICATION # APPLICATION DATE Du Clos, Terry 8,013,120 9/6/2011 C-Reactive Protein and Its Use to 12/083,055 8/11/2008 Treat Systemic Lupus Erythematosus and Related Conditions

Lovchik, Julie 8,192,720 6/5/2012 Compositions and Methods for 12/701,149 2/5/2010 Lyons, Clifford Detection, Prevention, and Treatment of Anthrax and other Infectious Diseases

CTSC PILOT AWARDS

The CTSC provides grant funding for a 12 month period for individuals who desire to do translational research. These grants provide funds for pilot projects that involve community related research. They are designed to generate pilot data that will result in a full application to the NIH for peer reviewed funding.

PRINCIPAL FUNDING FUNDING FUNDING TITLE OF PROJECT/SUBMISSION INVESTIGATOR DEPT AMOUNT BEGIN DATE END DATE

Identification of Biomarkers for Susceptibility to Severe Malarial Anemia DJ Perkins Internal Medicine $ 25,000 4/1/11 3/31/12 Gene expression profiling in airway epithelial cells in cigarette smoke-exposed non-human primates Toru Nyunoya Internal Medicine $ 20,000 4/1/11 3/31/12 A Web-Based Intervention to Reduce Disparities in Childhood Internal Medicine Behavioral Health Tamar Ginossar $ 20,000 4/1/11 3/31/12 Obesity-related host susceptibility factors for asthma in women Akshay Sood Internal Medicine $ 40,000 4/1/11 3/31/12 Managing Muscle Autophagy through the Heart Shock Response Pope Moseley Internal Medicine $ 25,000 8/1/11 7/31/12

Targeting 1L-12 as a Novel Treatment for Falciparium Malaria DJ Perkins Internal Medicine $ 33,000 10/1/11 9/30/12 A comparative Study of the efficacy of mindfulness-based stretching and breathing exercise as a complementary therapy for posttraumatic stress disorder versus treatment as usual Mark Burge Internal Medicine $ 21,830 10/1/11 9/30/12 Methylomic Profiles of Asthma Akshay Sood Internal Medicine $ 25,000 12/1/11 11/30/12

OTHER ACTIVITIES In 2011, the department provided financial incentives to those who served on the Promotions and Tenure Dossier Review Committee. During this year, the Office of Research monitored attendance by the department’s representatives and provided reimbursement when the faculty member fulfilled their commitment.

In the Summer of 2012, the Division of Translational Informatics became housed in the DOIM, and the Division of Nephrology welcomed a new Chief, Dr. Mark Unruh. Both additions will enhance Internal Medicine’s research portfolio.

Through the use of bulletin boards and e-mail notices, the Office of Research keeps faculty and staff apprised of new developments in the Office of Research, the Pre-Award Office, other HSC offices, and NIH and other funding agencies. The office also disseminates information on new opportunities to obtain external funding. Faculty members are encouraged to discuss any difficulties or obstacles they face when conducting research activities. This allows the Office of Research to act as a liaison between the HSC Pre-Award Office, the Financial Services Division, other faculty, and staff to effectively resolve any issues and to accelerate the department’s research enterprise.

DoIM’s Office of Research also provided significant assistance in the following areas:  proposal development assistance, including project budgeting, and navigating new online submission portals  reviewing and obtaining departmental endorsement of 150 applications for external sponsored funding  collaborating with HSC Post-Award Office and DoIM’s Accountants for the compliance, post-award monitoring and oversight of accounts  maintenance of sponsored project data for the Department  Assisted five faculty with IRB applications, amendments and renewals

PUBLICATIONS AND OTHER SCHOLARLY ACTIVITY OF THE OFFICE Department of Internal Medicine Peer-Reviewed Publications Five-Year History 2007-2011

200

150

100

50 NumberofPublications 0 2007 2008 2009 2010 2011

Since 2007, DOIM Faculty has produced 760 scholarly peer-reviewed scientific publications.

NATIONAL PRESENTATIONS AND PROFESSIONAL ACTIVITIES BY THE OFFICE

No National Presentations.

Dr. David Schade continues to represent DOIM on committees that ultimately promote and showcases the Department’s research. He is a member of the Research Allocation Committee, the Research Strategic Planning Committee, and the SOM Space Committee. He attends all regularly scheduled meetings and disseminates pertinent information to the Department. At the request of the Chairman of the DoIM, Dr. Schade also serves on the VA BRINM Committee, which reviews funding for VA investigators. It meets quarterly and also includes a daylong retreat. In the Summer of 2012, Dr. Schade was named a Distinguished Professor of Medicine.

Marisa Sanchez has attended five research centered symposiums, both on the Main Campus and the HSC Campus to get acquainted with the research environment at UNM. Her attendance at a full day seminar offered by the Human Research Protection Office, has enabled her to better assist faculty with their IRB needs.

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

 Continue to assist faculty and administrative staff with all applications for external funding.  Keep current with University and agency policies and procedures affecting research and funding by attending meetings, and becoming an active member of the Research Administrators Network, the National Council of University Research Administrators, and attend available online seminars offered by the National Institutes of Health, and the UNM-HSC Office of Research.  Inform departmental faculty and staff of changes in policies and procedures affecting both conducting research and securing funds for support.  Monitor research activities—contract and grant proposals and awards— by division and disseminate the results as requested.  Recruit faculty with strong investigative background. Whenever possible, new faculty recruits are expected to come with peer reviewed funding or the strong likelihood of future research funding. Thus, divisions are encouraged to include research as a criterion for hiring.  Increase membership in national research organizations and presentations at national meetings and encourage submission of peer review publications. The DoIM’s Office of Research may be able to provide direct financial support to faculty and trainees for travel, meeting registration, and per diem for scientific publications.  The Office of Research coordinates The Hallway Awards Program which is designed to recognize and reward individuals who, consistent with the departmental mission, have gone above and beyond their formal, identified job duties to exceed the needs of our patients, visitors, faculty and staff.

OFFICE OF VA AFFAIRS

ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Ravi Durvasula, MD Professor Chief of Medicine for New Mexico VA Health Care System Vice Chair for VA Affairs, Department of Internal Medicine

Henry Lin, MD, Associate Chief of Medicine and Section Chief, Division of Gastroenterology, VA Medicial Center

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

GOALS  Promote the academic mission of DOIM  Expand the research portfolio of DOIM  Develop innovative curricula for education of house staff  Provide unique clinical training opportunities  Leverage resources of VHA to strengthen DOIM

EDUCATION  Hospitalist curriculum: a comprehensive curriculum covering seminal topics of Internal Medicine over 52 blocks has been implemented for the education of residents and students.  Quality-related research: outcomes research activities related to in-patient care of conditions such as diabetes have been incorporated into a curriculum for house-staff education.  Medical Informatics: a revised curriculum for ambulatory internal medicine residents is under development to incorporate medical informatics and population registry-driven care.  Outcomes and Translational Medicine: VA-based faculty (Murata, Hoffman, Charlton) are involved in didactic education in programs such as Masters in Clinical Science, Global Health and Internal Medicine residency  Rural health initiatives: these educational efforts dovetail with population-based programs.  Telemedicine: VA-based faculty members have participated in several elements of Project ECHO; Dr. Murata has played a leading role in outcomes analysis and education of students and house-staff.  Training to Medical, PA, Nursing, Pharmacy students and all residents and fellows.

RESEARCH  Continued growth of research program and research-track faculty has occurred at the VA Medical Center.  VERA reimbursement, the indirect costs generated by VA research, increased from $7 million in 2005 to $20 million in 2011.  Medicine Service at the New Mexico VA Health Care System is one of the top 12 research facilities in the national VA system. Overall, the NM VA is ranked #20 in the country for research funding.  Currently, New Mexico VA Health Care System is the leading research center of VISN 18, the Southwest VA System.

CENTER OF EXCELLENCE IN CELLULAR AND MOLECULAR MEDICINE  This basic science center opened in Feb 2008 and is the flagship of the Medicine Service research program in laboratory science.  Currently 19 faculty are based in the Center.  Nearly $20 million in extramural grant support has accrued to faculty members of this Center.  Nearly 50 UNM-based trainees at all levels are associated with the Center. These include UNM undergraduate students, medical students, residents, fellows, graduate students and post-doctoral fellows.  Areas of expertise represented in the Center include GI, ID, Pulmonary, Geriatrics, Endocrinology and Rheumatology.  The Center houses 9 faculty with RO1 and R21 grants (Ma, Lin, Boedeker, Durvasula, Gresham, Hall, Villareal, DuClos and Mao)  There are 6 faculty members with VA Merit Review grants.  The Center offers a State-of-the-Art training facility for research in molecular biology, cell science, paratransgenics, microbiology, vector biology, immunology and vaccinology.  UNM house staff/students have published nearly 50 papers, abstracts and chapters in the past 5 years through affiliation with Center faculty.  Infectious diseases fellows have published 13 papers in last 3 years alone through affiliation with the Lee and Durvasula labs.  The Center offers highly specialized labs in fungal pathogenesis (Lee), paratransgenesis (Durvasula), epithelial cell biology (Ma), gut microbiology (Lin, Boedeker), vaccine development (Gresham), immune mediators (DuClos), metabolic bone diseases (R. Villareal) and cancer biology (Mao).  An additional 40,000 sq ft of research space is planned. New research space opened in 2011 includes 4000 sq ft of wet labs (Bldg 67). In 2013, 10,000 sq ft of wet labs and animal care facilities will be opened (Bldg 10). In 2014, a new 25,000 sq ft combined basic science and clinical research facility will be opened (BRINM Research Center). Over 90% of research is housed within Medicine Service. This allows for ongoing recruitment of physician-scientists.

THE VA CENTER FOR HEALTH INFORMATICS AND OUTCOMES RESEARCH  This Center is the research arm of DOIM’s Academic General Internal Medicine Division.  Leadership of this Center comes from Glen Murata,M.D.  This Center houses seven faculty currently with over 15 major research and training grants.  This Center was recently awarded one of seven VA National SCAN Center grants in partnership with UNM ECHO.  Planned additions of faculty to the Center include those with primary appointments in Geriatrics, Heme- Onc, Nephrology and General Medicine.  The VA Center for Health Informatics and Outcomes Research maintains a partnership with CTSC and MCS Programs at UNM.  The Center plays a leading role in Rural Health Research.  The Center plays a leading role in VHA Quality Initiatives such as Diabetes care, CRC screening, Women’s health, High-risk patient registries.  Partnership with DOIM and HSC in development of a Medical Informatics Program is underway, with the aim of creating a New Mexico Informatics Repository.  Over 200 publications and presentations, many including UNM junior faculty and house staff, have accrued from the faculty of this Center.

MEDICINE SERVICE: NEW CLINICAL AND EDUCATIONAL OFFERINGS  The Medical Informatics Service allows for new faculty and house staff training (see above).

CARDIOLOGY  In 2012, two new Cardiac Cath Labs will open, playing an important role in education and training of Cardiology Fellows.  The VA has a full-service Electrophysiology Program, which plays a key role in Cardiology Fellowship training.

GASTROENTEROLOGY  The VA Medical Center Medicine Service houses a $7 million GI Procedures Suite that leads all VA facilities in the nation in RVU’s, providing opportunities for new faculty and fellows.

GERIATRICS  Medicine Service houses a state-of-the- art NIH-funded Exercise Center for Exercise and Elderly Frailty Studies (D. Villareal, PI). Dr. Dennis Villareal, Professor of Geriatrics with Tenure has several NIH and VA Merit Review grants NEW 18-BED PATIENT RECOVERY BAY IN THE GI PROCEDURES SUITE and recently had a landmark article in

NEJM on exercise and the elderly. This Center actively recruits elderly veterans in NM and is a valuable clinical translational facility

HOSPITAL MEDICINE  A 24-hour Hospitalist Service is under development, with hiring of 3 nocturnists. This will provide continuous resident supervision and education.

PULMONARY AND CRITICAL CARE MEDICINE  The largest Sleep Center in NM is under construction with opportunities for new faculty and fellowship training. This was made possible by a $5 million VA-DoD award to Dr. Jenny Mao, Professor with Tenure of Pulmonary and Critical Care.

INFECTIOUS DISEASES  A highly successful Antimicrobial Stewardship Program under the direction of Drs. Sam Lee (Associate Professor with Tenure of Infectious Diseases) and Susan Kellie (Professor of Infectious Diseases) offers valuable training for residents in Medicine and Pathology as well as ID Fellows.

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

 Continued growth in basic science and outcomes research portfolios remains a top priority. Recruitment of physician scientists in Cardiology, GI, ID, General Medicine, Nephrology and Geriatrics is ongoing.  Increased efforts for joint appointments of research faculty are underway, to bridge UNM and VA missions.  Expanded curricula for house staff will ensue from the myriad clinical and translational activities of VA- based faculty.  Fellowship training and mentorship continues to expand and greater participation of fellows and junior faculty in hypothesis-driven research is a priority.  The VA Medical Center’s Medicine Service continues to strive for national prominence. An immediate goal is to break into the top 10 in the country in research funding while establishing informatics-driven clinical practice that sets the standard for the nation.

APPOINTMENTS

FACULTY

Name Title Effective date Ivan Correa, MD Staff Physician, Geriatric Medicine 8/15/2011 Meredith Prevost, MD Staff Physician, Hospitalist 11/7/2011 Sepehr Khashaei, MD Staff Physician, Hospitalist 4/2/2012

SEPARATIONS

FACULTY

Name Title Effective date Elizabeth Burpee, MD Staff Physician, Hospitalist 5/25/2012

OUTSIDE SPONSORED RESEARCH

BRINM Investigator Grant Submissions and Funding - Medicine Services

Investigator Project Title Agency Submitted Period of Performance Total Status Dynamic Regulation of Epithlial University of Arizona/ Edward Boedeker, Cell Survival by Enteropathogenci National Institutes of NA 7/1/11-6/30/12 $21,468 Awarded MD (Subaward) E. Coli Health Dual beneficial vaccine development against diarrhea Edward Boedeker, caused by ETEC and EPEC using an National Institutes of May 16, 2011 7/1/12-6/30/16 $377,450 Submitted MD (Subaward) intimin-toxoid fusion antigen Health ‘Int280-STa13-LTA2:B’ and a pig challenge model Edward Boedeker, A novel vaccine to prevent National Institutes of March 26, 2012 9/1/12 – 8/31/16 $1,338,48 Submitted MD Clostridium difficile colitis. Health Antibody-based Paratransgenics for Pierce's Disease: Advanced Ravi Durvasula, MD Methods for Transmission USDA Jan. 27, 2012 8/1/12 – 7/31/16 $500,000 awarded Blocking and Environmental Monitoring Second Generation Ravi Durvasula, MD Paratransgenics for Pierce’s USDA March, 2010 10/1/10- 9/30/13 $400,000 awarded Disease Microencapsulation of Bill and Malinda Gates Ravi Durvasula, MD entomopathgenic fungi for gated May 16, 2012 9/1/12 – 4/31/12 $100,000 Selected Foundation release in Desert locus Feasibility of grape seed extract National Institutes of Jenny Mao, MD Feb. 16, 2012 9/1/12 – 8/31/14 $341,825 Submitted for lung cancer chemoprevention Health Patient-Centered Role of ALDH2 in Cigarette Toru Nyunoya, MD Outcomes Research Jan. 13, 2012 7/1/12 – 6/30/2014 $40,000 Awarded Smoke-Induced Emphysema Institute (PCORI) FAMRI Clinical Innovators Award Toru Nyunoya, MD FAMRI Sept. 26, 2011 7/1/12-6/30/15 $325,500 Submitted Program Patient-Centered Innovative Access to Chronic Karen Servilla, MD Outcomes Research Dec. 1, 2011 8/1/2012 – 7/31/2014 $613,065 Submitted Disease Care (I-CARE) Institute (PCORI) Weight Loss and Exercise in Frail National Institutes of Dennis Villareal, MD Feb. 22, 2012 12/1/12 – 11/30/2017 $2,994,781 Submitted Obese Elderly Subjects Health

Outside research by Internal Medicine faculty associated with the VA Medical Center

Project Faculty Sponsor Name Project Title type Sponsor Number Start Stop F A Direct Total T cruzi Molecular Targets NIH/National 5R01AI066045- Durvasula, Ravi for Vector Research 2/1/2011 1/31/2012 0 0 0 Institutes of Health 04 Paratransgenesis Bacterial Overgrowth Lin, Henry Chia-nan VA Merit Review Associated with Chronic Research VAMC 20939/Lin 07/01/2008 06/30/2012 50,000 450,000 (Gastroenterology) Award Multi-Symptom Illness Complex Ma, Thomas Y. Regulation of Intestinal VA Merit Review Research VAMC 07/01/2004 06/30/2012 150,000 782,000 (Gastroenterology) Paracellular Permeability TNF-a modulation of Ma, Thomas Y. NIH/National intestinal epithelial Research NIH 2009 2014 235,000 1,675,000 (Gastroenterology) Institutes of Health permeability. IL-1b modulation of Ma, Thomas Y. NIH/National intestinal epithelial Research NIH 2009 2014 230,000 1,500,000 (Gastroenterology) Institutes of Health permeability Drug-eluting Stents vs. Ratliff, D.M VA Cooperative Bare metal Stents in Research DIVA, CSP #571 2010 present (Cardiology) Study No. 571 Saphenous Vein Graft Antioplasty Comparison of Radial Artery Grafts vs. Ratliff, D.M VA Cooperative Saphenous Vein Grafts Research WAVE 5 2006 present (Cardiology) Study No. 474 in Coronary Artery Bypass Surgery CYPAI Gene and Villareal, D VA Merit Grant Pharmacogenetics of Clinical CX000424 10/01/10 09/30/14 496,805.00 (Geriatrics) 1101 response to Testosterone Therapy

Department of Veterans Affairs Merit Program

Investigator DoIM Division Type of award Timeframe Amount Gerald Charlton Cardiology VISN 18 AWARD (pilot) 1/1/2012 - 12/31/12 $40,000

Terry Duclos Rheumatology Merit grant award $650,000

Henry Lin Gastroenterology Merit grant award $650,000

D. Michelle Ratliff Cardiology Cooperative Studies Site Investigator 1/5/2012

Karen Servilla Nephrology Cooperative Studies Site Investigator 4/14/2008

Reina Villareal Endocrinology Merit grant award 10/01/11 - 9/30/14 $650,000

Samuel Lee Infectious Disease Merit grant award 1/1/2012 - 12/31/15 $650,000

ACADEMIC DIVISIONS

CARDIOLOGY

ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Warren Laskey, MD S. Flinn Professor of Medicine Chief, Division of Cardiology

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

EDUCATION Dr. Craig Timm was named Senior Associate Dean for Education in February, 2012.

Dr. Mark Sheldon was accepted into the UNM Medical Education Scholars Program. Dr. Sheldon has also completed his first full year as fellowship training program director in cardiology.

Dr. Bart Cox has delivered a number of interactive lectures on the management of heart failure as part of Project ECHO-HF (TeleHealth).

RESEARCH AND SCHOLARLY ACTIVITIES Dr. Laskey serves on the American Heart Association’s Get with the Guidelines Science Committee as well as the heart Failure Working Group. The combined manuscript output from the CAD and HF portions of the GWTG program was over 30 publications for 2012.

The Division and UNMH were again recipients of the AHA Gold Plus Award for its Heart Failure Program and outstanding compliance with performance metrics. Again UNMH was mentioned in the US News and World Report on institutions with high levels of performance and outcomes in cardiovascular disease.

Drs. Laskey and Dodendorf were speakers for the June 26, 2102 American Heart Association nationally-broadcast webinar entitled “Roadmap to the Target: Heart Failure Honor Roll.”

UNM’s program in advanced heart failure has received continuing certification from Joint Commission. Many 25,000,000 individuals contribute to this effort are acknowledged 20,000,000 here: Dr. Warren Laskey, Bart Cox, Mary Hawkins, Elaine Stack, Diane Dodendorf PhD, Sharilyn 15,000,000 Woloschuk, Allison Burnett, Bonnie Richardson, James 10,000,000 Effinger, Joe Anderson, Kristen Tarantino, Lorena YTD actual 5,000,000 Beeman, Lynette Gutierrez, Maria Goergen, Mela Prior YTD Chapman, Melissa Johnson, Paul Nelson, Philip - Mercurio, Renee Donohoe, Roxroy Reid, Tiffany Montoya.

Dr. Gerald Charlton was awarded a new Investigator Grand from the VA to study “Impact of Project Scan- ECHO Telehealth Implementation and Patient FIGURE 2 Registries on Practice Patterns and HbA1c in Veterans

53 with Diabetes”

CLINICAL OPERATIONS The division of cardiology continues to grow in several cost centers (see figure 1) and patient volumes (see figure 2).

Despite declining reimbursements in several key areas and a continuing adverse payor mix, the hard work of the full-time faculty has resulted in a meaningful revenue stream for the institution in FY12.

The division’s Project STEMI- the efficient management of patients with ST segment elevation MI- under the expert direction of Dr. Mark Ricciardi continues to achieve kudos for its regional and national reputation. The UNM program has been in the top 5 in the UHC database for each of the past 3 years - a remarkable accomplishment.

An important development in the division’s expansion of clinical services and access is embodied in the creation of the “UNM Cardiology West-Side Clinic”. Staffed by Dr. Robert DuBroff - an established practitioner in the Albuquerque region for over 20 years and now full time faculty in the division- and Dr. Abinash Achrekar, the West Side Clinic represents new opportunity for growth of clinical services in an area 12,000 previously committed to other health care systems. The improved access for patients 10,000 from points west, north and northwest of the city proper is reflected in the data in 8,000 Figure 2. Specifically, the FY 12 growth in FY11 out-patient visits prior to the opening of the 6,000 West Side Clinic was 108% and 125.7% FY12 4,000 subsequent to the opening. 2,000 COMMUNITY ACTIVITIES Dr Laskey continues to serve as President of 0 the New Mexico Chapter of the American inpatient outpatient ED Heart Association. FIGURE 3 Dr Abinash Achrekar; has a monthly health and wellness column titled "The Good Doctor" in the Albuquerque Local IQ Magazine, which has distribution to over 300,000 people in the community. His column has been running since early 2008 and topics have ranged from How to find a primary care doctor to How to lower your cholesterol. This venue provides readers an open forum in which to ask health related questions to Dr. Achrekar a UNM faculty member.

ADMINISTRATION Dr Gerald Charlton was named Director for VISN18 Project SCAN ECHO- a telehealth program within the VA.

Dr. Warren K Laskey continues to serve on the UNMH Board of Trustees.

HONORS AND AWARDS The division/hospital was the recipient of Joint Commission’s certification for our program in advanced heart failure. As well, the division/hospital received a #1 rating from the AHA’s Get With the Guidelines Target: Heart Failure effort (see above).

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

CLINICAL PROGRAM

 Planning is continuing for provider and support personnel staffing at the West Side Clinic  Planning for the out-patient facility has been completed; architectural drawings signed-off; and preparations underway for the move from 5 ACC to Lands West within the next 12-18 months  Continued growth of the clinical program is dependent on the number of faculty. The division is seeking institutional approval for an additional 3 FTE. This would allow us to not perform meaningful out-reach but station providers on the west side and to provide much relief for a tiring cath lab contingent of only 3 operators. The increase in personnel is vital to the division’s ability to provide extant, and expanded, services.

EDUCATIONAL PROGRAM Continued emphasis in the division on the mentoring of junior faculty by senior faculty and mentoring of our fellows by all faculty. To this end, Dr Sheldon will be participating in Medical Education Scholarship Program (MES).

QUALITY AND OUTCOMES PROGRAM  The division remains committed to its outcomes reporting for both coronary heart disease and heart failure. Despite the departures of key personnel in many aspects of both programs, the division has been actively recruiting replacements for Becky Mayo, Jennifer Mariani, Sen Nguyen, and Eleanor Miranda. The focus of our effort will be on quantifying and decreasing the risk of hospital re-admission within 30 days for our HF patients  Participation in UNM’s renowned Project ECHO in the form of heart failure consultative services represents an exciting new dimension for our program. Dr Bart Cox and mid-levels Mary Hawkins and Elaine Stack will be leading that effort from our division. This area naturally overlaps with the division’s outreach efforts (see below)

APPOINTMENTS

FACULTY Name Title Effective date Richard Snider, MD Assistant Professor of Medicine 10/1/2011 Michael West, MD Assistant Professor of Medicine 10/1/2011

STAFF None

SEPARATIONS

FACULTY Name Title Effective date Mel Peralta, MD Assistant Professor of Medicine 2/29/2012 Robert Taylor, MD Associate Professor 1/1/2012

STAFF None

PUBLICATIONS OF THE DIVISION AND FACULTY

Jonathan Abrams, M.D. N/A

Abinash Achrekar, M.D. 1. Person-to-person interventions targeted to parents and other caregivers to improve adolescent health: a community guide systematic review. Burrus B, Leeks KD, Sipe TA, Dolina S, Soler R, Elder R, Barrios L, Greenspan A, Fishbein D, Lindegren ML, Achrekar A, Dittus P; Community Preventive Services Task Force. Am J Prev Med. 2012 Mar;42(3):316-26. Review.

Bina Ahmed, M.D. 1. Ahmed B, Sheldon M, Ricciardi M et al. Appropriate use of Nitroglycerin with Intravascular Ultrasound. Accepted. Journal of Invasive Cardiology 2012 2. Ahmed B, Dauerman HL, Winthrop P et al. Recent Changes in Practice of Elective PCI for Stable Angina. Circulation: Quality and Outcomes. 2011 3. Ahmed B, Lischke S, Straight F, Dauerman HL. Angiographic Predictors of Vascular Complications Among Women Undergoing Cardiac Catheterizations. Journal of Invasive Cardiology. 2010; 22(11):517-8 4. Anderson PR, Ahmed B, Dauerman HL et al. Two Hour Bivalirudin Infusion After PCI for ST Elevation Myocardial Infarction. Journal of Thrombosis and Thrombolysis. 2011

Gerald Charlton, M.D. N/A

Bart Cox, M.D. N/A

Robert DuBroff, M.D. N/A

Milton Icenogle, M.D. N/A

Shmuel Inbar, M.D. 1. Deadly proposal: a case of catecholaminergic polymorphic ventricular tachycardia. Heiner JD, Bullard- Berent JH, Inbar S. Pediatr Emerg Care. 2011 Nov;27(11):1065-8.

Warren Laskey, M.D. 1. Incidence and Predictors of 30-Day Hospital Readmission Rate Following Percutaneous Coronary Intervention (from the National Heart, Lung, and Blood Institute Dynamic Registry). Ricciardi MJ, Selzer F, Marroquin OC, Holper EM, Venkitachalam L, Williams DO, Kelsey SF, Laskey WK. Am J Cardiol. 2012 Jul 30. [Epub ahead of print] 2. Improvement in arterial stiffness following cardiac rehabilitation. Laskey W, Siddiqi S, Wells C, Lueker R. Int J Cardiol. 2012 Jul 13. [Epub ahead of print] 3. Trends in smoking cessation counseling: experience from american heart association-get with the guidelines. Huang PH, Kim CX, Lerman A, Cannon CP, Dai D, Laskey W, Peacock WF, Hernandez AF, Peterson ED, Smith EE, Fonarow GC, Schwamm LH, Bhatt DL. Clin Cardiol. 2012;35(7):396-403. doi: 10.1002/clc.22023. 4. Age and Gender Differences in Quality of Care and Outcomes for Patients with ST-segment Elevation Myocardial Infarction. Bangalore S, Fonarow GC, Peterson ED, Hellkamp AS, Hernandez AF, Laskey W, Peacock WF, Cannon CP, Schwamm LH, Bhatt DL; Get with the Guidelines Steering Committee and Investigators. Am J Med. 2012 Jun 27. [Epub ahead of print]

5. Reperfusion Strategies and Quality of Care in 5339 Patients Age 80 Years or Older Presenting With ST- Elevation Myocardial Infarction: Analysis from Get With The Guidelines-Coronary Artery Disease. Medina HM, Cannon CP, Fonarow GC, Grau-Sepulveda MV, Hernandez AF, Frank Peacock W, Laskey W, Peterson ED, Schwamm L, Bhatt DL; on behalf of the GWTG Steering Committee and Investigators. Clin Cardiol. 2012 Jun 28. doi: 10.1002/clc.22036. [Epub ahead of print] 6. Quality of Care and Outcomes Among Patients With Acute Myocardial Infarction by Level of Kidney Function at Admission: Report From the Get With The Guidelines Coronary Artery Disease Program. Vasaiwala S, Cannon CP, Fonarow GC, Peacock WF, Laskey W, Schwamm LH, Liang L, Hernandez AF, Peterson ED, Rosas SE, Bhatt DL; Get With The Guidelines Steering Committee and Investigators. Clin Cardiol. 2012 Jun 28. doi: 10.1002/clc.22021. [Epub ahead of print] 7. An analysis of implantable cardiac device reliability. The case for improved postmarketing risk assessment and surveillance. Laskey W, Awad K, Lum J, Skodacek K, Zimmerman B, Selzman K, Zuckerman B. Am J Ther. 2012 Jul;19(4):248-54. 8. 2012 American College of Cardiology Foundation/Society for Cardiovascular Angiography and Interventions expert consensus document on cardiac catheterization laboratory standards update. A report of the American College of Cardiology Foundation Task Force on Expert Consensus documents. Bashore TM, Balter S, Barac A, Byrne JG, Cavendish JJ, Chambers CE, Hermiller JB Jr, Kinlay S, Landzberg JS, Laskey WK, McKay CR, Miller JM, Moliterno DJ, Moore JW, Oliver-McNeil SM, Popma JJ, Tommaso CL. J Am Coll Cardiol. 2012 Jun 12;59(24):2221-305. Epub 2012 May 8. No abstract available. 9. 2012 American college of cardiology foundation/society for cardiovascular angiography and interventions expert consensus document on cardiac catheterization laboratory standards update: American college of cardiology foundation task force on expert consensus documents society of thoracic surgeons society for vascular medicine. Bashore TM, Balter S, Barac A, Byrne JG, Cavendish JJ, Chambers CE, Hermiller JB Jr, Kinlay S, Landzberg JS, Laskey WK, McKay CR, Miller JM, Moliterno DJ, Moore JW, Oliver-McNeil SM, Popma JJ, Tommaso AC, Harrington RA, Bates ER, Bhatt DL, Bridges CR, Eisenberg MJ, Ferrari VA, Fisher JD, Gardner T, Gentile F, Gilson MF, Hlatky MA, Jacobs AK, Kaul S, Moliterno DJ, Mukherjee D, Rosenson RS, Weitz HH, Wesley DJ. Catheter Cardiovasc Interv. 2012 May 8. doi: 10.1002/ccd.24466. [Epub ahead of print] No abstract available. 10. Care and outcomes of Asian-American acute myocardial infarction patients: findings from the American Heart Association Get With The Guidelines-Coronary Artery Disease program. Qian F, Ling FS, Deedwania P, Hernandez AF, Fonarow GC, Cannon CP, Peterson ED, Peacock WF, Kaltenbach LA, Laskey WK, Schwamm LH, Bhatt DL; Get With The Guidelines Steering Committee and Investigators. Circ Cardiovasc Qual Outcomes. 2012 Jan;5(1):126-33. Epub 2012 Jan 10. 11. Comparison of bare-metal and drug-eluting stents in patients with chronic kidney disease (from the NHLBI Dynamic Registry). Green SM, Selzer F, Mulukutla SR, Tadajweski EJ, Green JA, Wilensky RL, Laskey WK, Cohen HA, Rao SV, Weisbord SD, Lee JS, Reis SE, Kip KE, Kelsey SF, Williams DO, Marroquin OC. Am J Cardiol. 2011 Dec 1;108(11):1658-64. Epub 2011 Sep 3.

Larry Osborn, M.D. N/A

Veena Raizada, M.D. 1. Angiotensin II-mediated left ventricular abnormalities in chronic kidney disease. Raizada V, Hillerson D, Amaram JS, Skipper B. J Investig Med. 2012 Jun;60(5):785-91.

D. Michelle Ratliff, M.D. 1. Radial artery grafts vs saphenous vein grafts in coronary artery bypass surgery: a randomized trial. Goldman S, Sethi GK, Holman W, Thai H, McFalls E, Ward HB, Kelly RF, Rhenman B, Tobler GH, Bakaeen FG, Huh J, Soltero E, Moursi M, Haime M, Crittenden M, Kasirajan V, Ratliff M, Pett S, Irimpen A, Gunnar W, Thomas D, Fremes S, Moritz T, Reda D, Harrison L, Wagner TH, Wang Y, Planting L, Miller M, Rodriguez Y, Juneman E, Morrison D, Pierce MK, Kreamer S, Shih MC, Lee K. JAMA. 2011 Jan 12;305(2):167-74.

Mark Ricciardi, M.D. 1. Incidence and Predictors of 30-Day Hospital Readmission Rate Following Percutaneous Coronary Intervention (from the National Heart, Lung, and Blood Institute Dynamic Registry). Ricciardi MJ, Selzer F, Marroquin OC, Holper EM, Venkitachalam L, Williams DO, Kelsey SF, Laskey WK. Am J Cardiol. 2012 Jul 30. [Epub ahead of print]

Carlos Roldan, M.D.

1. Beaded necklace-like image observed by real time three-dimensional transesophageal echocardiograhy as evidence of bacterial vegetations in a dialysis catheter. Ponce SG, Roldan CA. Echocardiography. 2012 Apr;29(4):E97-9. doi: 10.1111/j.1540-8175.2011.01619.x. Epub 2012 Feb 14. 2. Greene ER, Yonan K, Sharrar J, Sibbitt WL, Qualls C, Roldan CA. "Middle Cerebral Artery Resistivity and Pulsatility Indices in Systemic Lupus Erythematosus: Evidence for Hyperperfusion?". Lupus 201 2;21(4)380-5. 3. Gasparovic C, Qualls C, Greene ER, Sibbitt WL Jr, Roldan CA. Blood Pressure and Vascular Dysfunction Underlie Elevated Cerebral Blood Flow in Systemic Lupus Erythematosus. J Rheumatol. 2012;39(4):752-8. 4. Jung RE, Chavez RS, Flores RA, Qualls C, Sibbitt WL Jr, Roldan CA. White matter correlates of neuropsychological dysfunction in systemic lupus erythematosus. PLoS One. 2012;7:e28373.

Books Roldan CA. The Ultimate Echo Guide. Publisher: Lippincott Williams & Wilkins. Philadelphia, PA. First Edition October 2004. Second edition Fall 2011– Published and debuted at the AHA scientific sessions in 11-2011.

Book Chapters 1. Roldan CA. Arterial Embolism. The AHA Clinical Cardiac Consult. Third edition 2011, pages 80-81.Wolters Kluwer/Lippincott Williams & Wilkins. Editor-in-Chief: J.V. (Ian) Nixon, M.D. 2. Roldan CA. Paradoxical Embolism.. The AHA Clinical Cardiac Consult. Third Edition 2011, pages 250-251. Wolters Kluwer/Lippincott Williams & Wilkins. Editor-in-Chief: J.V. (Ian) Nixon, M.D. 3. Roldan CA. Echocardiography Findings in Systemic Diseases Characterized by Immune-mediated Injury. The Practice of Clinical Echocardiography . W. B. Saunders Company. Editor-in-Chief: Catherine Otto, MD. Fourth Edition, Chapter 37, Spring 2012.

Mark Sheldon, M.D. 1. Ahmed B, Sheldon M, Ricciardi M et al. Appropriate use of Nitroglycerin with Intravascular Ultrasound. Accepted. Journal of Invasive Cardiology 2012

T. Craig Timm, M.D 1. The association between intolerance of ambiguity and decline in medical students' attitudes toward the underserved. Wayne S, Dellmore D, Serna L, Jerabek R, Timm C, Kalishman S. Acad Med. 2011 Jul;86(7):877-82. 2. Reuniting public health and medicine: the University of New Mexico School of Medicine Public Health Certificate. Geppert CM, Arndell CL, Clithero A, Dow-Velarde LA, Eldredge JD, Kalishman S, Kaufman A, McGrew MC, Snyder TM, Solan BG, Timm CT, Tollestrup K, Wagner LK, Wiese WH, Wiggins CL, Cosgrove EM. Am J Prev Med. 2011 Oct;41(4 Suppl 3):S214-9. Erratum in: Am J Prev Med. 2012 Jul;43(1):123. Eldredge, Jonathan P [corrected to Eldredge, Jonathan D].

Wyatt Voyles, M.D. 1. Kirby BS, Crecelius AR, Voyles WF, Dinenno FA. Journal of Physiology. Modulation of postjunctional adrenergic vasoconstriction during exercise and exogenous ATP infusions in ageing humans. 589 (Pt 10). 2641-53. May 2011. 2. Markwald RR, Kirby BS, Crecelius AR, Carlson RE, Voyles WF, Dinenno FA. Journal of Physiology. Combined inhibition of nitric oxide and vasodilation prostaglandins abolishes forearm vasodilation to systemic hypoxia in healthy humans. 589 (Pt8). 1979-90. Apr 2011.

3. Crecelius AR, Kirby BS, Voyles WF, Dinenno FA. Journal of Physiology. Augmented skeletal muscle hyperaemia during hypoxic exercise in humans is blunted by combined inhibition of nitric oxide and vasodilating prostaglandins. Epub ahead of print. May 2011. 4. Crecelius AR, Kirby BS, Richards JC, Garcia LJ, Voyles WF, Larson DG, Luckasen GJ, Dinenno FA. Am J Physiol Heart Circ Physiol. Mechanisms of ATP-mediated vasodilation in humans: Modest role for nitric oxide and vasodilating prostaglandins. 301(4). 1522-39. Jul 2011. 5. Kirby BS, Crecelius AR, Voyles WF, Dinenno FA. Circ Res. Impaired skeletal muscle blood flow control with advancing age in humans: attenuated ATP release and local vasodilation during erythrocyte deoxygenation. 111(2). 220-30. May 2012.

Michael West, M.D. N/A

OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

Jonathan Abrams, M.D. N/A

Abinash Achrekar, M.D COMMUNITY OUTREACH  Dr. Achrekar has a monthly health and wellness column titled "The Good Doctor" in the Albuquerque Local IQ Magazine, which has distribution to over 300,000 people in the community. His column has been running since early 2008 and topics have ranged from How to find a primary care doctor to How to lower your cholesterol. This venue provides readers an open forum in which to ask health related questions to Dr. Achrekar a UNM faculty member.

Bina Ahmed, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  Gender Related Differences in Predictors of Retroperitoneal Bleeding, American Heart Association Conference, November 2011.

Gerald Charlton, M.D. N/A

Bart Cox, M.D. COMMUNITY OUTREACH  Dr. Cox along with Sharilyn Woloschuk, MBA, MHM, BSN, RN, presented March, 2012, our Heart Failure program to the Albuquerque Coalition for Healthcare Quality.

PROFESSIONAL AFFILIATIONS  Dr. Cox was appointed the Medical Director In-Patient Services on 7 South, effective March 1, 2012.  Dr. Cox was awarded the 2011-2012 "Outstanding University of New Mexico Attending Award" from the Family Medicine Residency Program at their graduation ceremony on Saturday, June 23, 2012.

Robert DuBroff, M.D. N/A

Milton Icenogle, M.D. N/A

Shmuel Inbar, M.D. N/A

Warren Laskey, M.D. PROFESSIONAL AFFILIATIONS  President of the New Mexico Chapter of the American Heart Association  Special Government Employee, CDRH, FDA  Abstract Reviewer, Annual Scientific Sessions, American College of Cardiology, Member  Abstract Reviewer, Annual Scientific Sessions, American Heart Association, Member  AHA Get With the Guidelines Quality Improvement Subcommittee, Member  AHA GWTG Science Sub-Committee, Member  Chairman, DSMB Toshiba Core 320, A Multi Center study combined Non-invasive Coronary Angiography and Myocardial Perfusion Imaging using 320-Detector Computed Tomography  Member, DSMBPLC Medical Systems, A Study to Evaluate RenalGuard ® System Safety and Efficacy When Compared with Standard Care in the Prevention of Contrast Induced Nephropathy in the Setting of a Catheterization Laboratory

COMMUNITY OUTREACH  President of the New Mexico Chapter of the American Heart Association

EDITORIAL BOARD  Editorial Board, Catheterization and Cardiovascular Diagnosis  Editorial Board, Current Controlled Trials in Cardiovascular Medicine  Editorial Board, Cardiovascular Engineering  Editorial Board, Cardiology  Editorial Board, Journal of Alternative and Complementary Medicine

Veena Raizada, M.D. N/A

D. Michelle Ratliff, M.D N/A

Mark Ricciardi, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  CME Update and Review of Internal Med 2011 - Acute Coronary Syndrome Rx: Taking It to the Next Level for General Practitioner, October 20, 2011

Carlos Roldan, M.D. N/A

T. Craig Timm, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  2012 Timm C (moderator), Moynahan K, Wolf K, May W, Anderson T Patient Safety and Quality Improvement Across the Medical Education Continuum,. Panel Discussion: WGEA/AAMC Regional Conference, 4/12 Asilomar CA, hosted by Keck USC SOM.  2011 Research in Medical Education Oral Presentations, Session Moderator: Craig Timm. The Question of Emotion in Medical School. AAMC National Meeting 11/11, Denver CO.  2011 GEA Task Force Members: Gusic M (Chair), Amiel J, Baldwin C, Chandran L, Fincher R, Mavis B, O’Sullivan P, Padmore J, Rose S, Simpson D, Stroebel H, Timm C, Viggiano T, Evaluating Educators for Academic Advancement: A Toolbox from the AAMC Task for on Educator Evaluation. Workshop AAMC National Meeting 11/11, Washington DC.  2011 Cosgrove E, Clithero A, Kalishman S, Kaufman A, Timm C. Velarde L, Wallerstein N, Wiese W. The University of New Mexico Public Health Certificate. Poster: AAMC Public Health in Medical Education Conference, 9/11, Cleveland OH.

Wyatt Voyles, M.D. N/A

Michael West, M.D. N/A

OUTSIDE SPONSORED RESEARCH

Project Faculty Sponsor Name Project Title type Sponsor Number Start Stop F A Direct Total National Institute Tsimane Life Study Achrekar, Abinash Research $10,000 of Aging

3RG96 Clinical Trial Ahmed, Bina Lilly USA, LLC Research 2/2012 2/2013 $41,940 $41,940 $41,940 Phase I

Dynamic Evolution of University of Laskey, Warren K. Percutaneous Coronary Research Wave 5/Laskey 4/2/2008 2/1/2012 0 0 0 Pittsburgh/NHLBI Intervention Novartis Ricciardi, Mark J. Pharmaceuticals Clinical Trial - Phase III Research CSPP100A2366 12/8/2008 9/12/2012 29,021 116,087 145,108 Corporation Brigham and Ricciardi, Mark J. Clinical Trial Phase 3 Research TIMI 52 SOLID 12/6/2010 12/5/2015 7,349 29,392 36,741 Women's Hospital Hamilton Health Ricciardi, Mark J. Clinical Trial - Phase 1 Research TOTAL/#103 6/17/2011 6/16/2015 7,349 29,392 36,741 Sciences Corp Libman-Sacks NIH/National Endocarditis and R01-HL04722- Roldan, Carlos A. Heart, Lung, and Neuropsychiatric Research 8/1/2011 7/31/2012 149,494 403,036 552,530 01-A6 Blood Institute Systemic Lupus Erythematosus A National Heart, Lung and Blood Institute Sponsored Study Identification of novel PRE-DETERMINE; genetic and biologic Biologic Markers Ratliff, D.M markers that predict Research 2010 present and SCD Cohort the risk of arrhythmic Study death in CAD patients with either prior MI or mild to moderate LV dysfunction

Project Faculty Sponsor Name Project Title type Sponsor Number Start Stop F A Direct Total Drug-eluting Stents vs. VA Cooperative Bare metal Stents in Ratliff, D.M Research DIVA, CSP #571 2010 present Study No. 571 Saphenous Vein Graft Antioplasty Atherothrombosis Intervention in A National Heart, Metabolic Syndrome Lung and Blood Ratliff, D.M with Low HDL/High Research 2006 present Institute Triglyceride and Impact Sponsored Study on Global Health Outcomes (AIM-HIGH) Comparison of Radial Artery Grafts vs. VA Cooperative Ratliff, D.M. Saphenous Vein Grafts Research WAVE 5 2006 present Study No. 474 in Coronary Artery Bypass Surgery A National Heart, Lung and Blood Institute Dynamic Sponsored Study Evaluation of Evaluation of early Ratliff, D.M Percutaneous procedural and long Research 2006 present Coronary term success of Intervention advancement in catheter based coronary interventions

CLINICAL IMMUNOLOGY AND RHEUMATIC DISEASES

ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Arthur D. Bankhurst, MD Professor of Medicine Chief, Division of Clinical Immunology and Rheumatic Diseases

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

We continue to run the Division of Rheumatology with three full time UNM physicians and two full time VA physicians who constitute the divisional attending staff at UNM, VAMC, IHS-PHS (Albuquerque), Carrie Tingley Juvenile Arthritis.

Aside from its extensive educational and clinical program, the Division continues to have the research activities supported by external funding from the pharmaceutical industry.

EDUCATION AND PROFESSIONAL DEVELOPMENT  The Division organizes an annual New Mexico Rheumatic Disease Conference in Santa Fe each year. The meeting in April 2012 attracted more than 60 providers, including essentially all of the rheumatologists from New Mexico and several from El Paso, Texas, and Durango. Colorado. The faculty included four internationally known individuals and was supported by restricted education grants from the pharmaceutical industry.  The Division’s educational activities in the Phase I and II curriculum will become a leader within the Department (as measured per divisional faculty). Participation details: o Foundations of Clinical Practice (Bankhurst, Fields, Konstantinov, Sibbitt) o Genetics (Konstantinov) o Immunology (Bankhurst, Fields, Konstantinov, Sibbitt) o Transitions (Bankhurst, Fields, Sibbitt)  Dr. Bankhurst presents the majority of the rheumatology talks at the Santa Fe IM Update.  Dr. Bankhurst conducts the weekly CME Rheumatology conference for Project ECHO.

RESEARCH AND SCHOLARLY ACTIVITIES  The Division has had a productive research program and plans to continue its efforts in clinical rheumatology and immunology.

CLINICAL OPERATIONS  Overall, the Rheumatology practice has improved such that we can accommodate new referrals within two weeks. This outpatient service has by far the shortest waiting time for new patients.  The Division of Rheumatology was previously awarded a $250,000.00 gift to increase patient care. The Division decided to utilize the funding to open an evening clinic and is now operating a successful evening clinic under the auspices of the Southwest Arthritis Foundation. The clinic is staffed by Dr. Bankhurst and Dr. Sibbitt.  Roderick Fields, M.D., joined our faculty at the University of New Mexico in September 2011 and has established a busy practice.

 The Division’s clinical activities have been greatly enhanced by the addition of Elizabeth Etherton, CNP, who is now fully trained as a specialist rheumatology provider.

ADMINISTRATION  The Unit Administrator who has been in place for three years has transferred to the College of Pharmacy (see more information, below).

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

RESEARCH AND SCHOLARLY ACTIVITIES  The Division plans to continue its efforts in clinical rheumatology and immunology.

CLINICAL OPERATIONS  We plan to continue our clinical activities at SRMC (Bankhurst, Fields, Sibbitt) and at the University. We hope to be able to achieve a new landmark for UNM subspecialty clinics of less than one week.

COMMUNITY ACTIVITIES  The Division will continue to participate in community activities including the CME Rheumatology conference for Project ECHO.

ADMINISTRATION  The Division plans to add an additional CNP, Gladys Moore, to the group in November 2012, supported by UNMH funds.  A new Unit Administrator with outstanding credentials will start in October 2012. We anticipate tha the administrative activities will resume optimally by December 2012.

APPOINTMENTS

FACULTY

Name Title Effective date Roderick Fields, MD Assistant Professor 9/19/2011

STAFF None

SEPARATIONS

FACULTY None

STAFF None

PUBLICATIONS OF THE DIVISION AND FACULTY

Arthur Bankhurst, M.D. 1. Sibbitt WL Jr, Band PA, Chavez-Chiang NR, Delea SL, Norton HE, Bankhurst AD. J. Rheumatol. A Randomized Controlled Trial of the Cost-Effectiveness of Ultrasound-Guided Intraarticular Injection of Inflammatory Arthritis. Epub ahead of print. Nov 2010. PMID:21078710 2. Haseler LJ, Sibbitt RR, Sibbitt WL Jr, Michael AA, Gasparovic CM, Bankhurst AD. Cardiovasc Intervent Radiol. Syringe and Needle Size, Syringe Type, Vacuum Generation, and Needle Control in Aspiration Procedures. Epub ahead of print. Nov 2010. PMID: 21057795 3. Sibbitt RR, Palmer DJ, Sibbitt WL Jr, Bankhurst AD. Cardiovasc Intervent Radio. Image-Directed Fine- needle Aspiration Biopsy of the Thyroid with Safety-engineered Devices. Epud ahead of print. Nov 2010. PMID: 21057794 4. Brooks WM, Sibbitt WL Jr, Kornfeld M, Jung RE, Bankhurst AD, Roldan CA. Arthritis Rheum. The histopathologic associates of neurometabolite abnormalities in fatal neuropsychiatric systemic lupus erythematosus. 62(7). 2055-63. Jul 2010. PMID: 20309864 5. Sibbitt WL Jr., Brooks WM, Kornfeld M, Hart BL, Bankhurst AD, Roldan, CA. Semin Arthritis Rheum. Magnetic resonance imaging and brain histopathology in neuropsychiatric systemic lupus erythematosus. 40(1). 32-52. Aug 2010. PMID: 20607688 6. Arora S, Kalishman S, thornton K, Dion D, Deming P, Parish B, Brown J, Komaromy M, Colleran K, Bankhurst AD, Katzman J, Harkins M, Curet L, Cosgrove E, Pak W. Hepatology. Expanding access to hepatis C virus treatment-Extension for Community Healthcare Outcomes (ECHO) project; disruptive innovation in specialty care. 52(3). 1124-33. Sep 2010. PMID: 20607688 7. Yaqub S, Ashraf U, Norton H, Gibb JI, Sibbitt WL Jr. Bankhurst AD. J Investigative Medicine. Outcomes and Cost-Effectiveness of Resident Performed Palpation-Guided Intraarticular Procedures in a Teaching Hospital. 59:161. 262. Jan 2011. 8. Kettwich LS, Sibbitt WL Jr., Chavez-Chiang N, DeLea S, Michael AA, Bankhurst AD. J Investigative Medicine. New Techniques for Subcutaneous Fat Biopsy. 59:188. 359. Jan 2011. 9. Norton H, Band P, Sibbitt WL Jr., Chavez-Chiang N, DeLea S, Bankhurst AD. J Investigative Medicine. Technique-Based Improvements of Intraarticular Injections for Osteoarthritis of the Knee. 59:188. 358. Jan 2011. 10. Norton H, Sibbitt WL Jr., Bankhurst AD, DeLea S, Chavez-Chaing N, Band P. J Investigative Medicine. A Randomized Controlled Trial of Cost-Effectiveness of Ultrasound-Guided Injections of Inflammatory Arthritis. 59:188. 357. Jan 2011. 11. Chavez-Chaing NR, Sibbitt WL Jr., Band PA, DeLea SL, Park KS, Bankhurst AD. Rheumatology Int. The Outcomes and Cost-Effectiveness of Intraarticular Injection of the Rheumatoid Knee. Jan 2011. Epub ahead of Print 12. Boyer NM, Roldan C, Yonan KA, Sharrar JM, Sibbitt WL Jr., Greene ER. J Investigative Medicine. Middle Cerebral Artery Resistivity and Pulsatility Indices in Systemic Lupus Erythematosus. 59:188-9. 360. Jan 2011. 13. Kettwich LS, Sibbitt WL Jr., Chavez-Chiang N, DeLea S, Norton H, Bankhurst A. J Investigative Medicine. Ultrasound-Guided Arthrocentesis of the Knee using New Aspirating Syrine Technologies. 59:162. 265. Jan 2011. 14. Ashraf U, Gibb JI, Norton H, Sibbitt WL Jr., Bankhurst AD. J. Investigative Medicine. Outcomes and Cost- Effectiveness of Ultrasound-Guided Procedures Performed in a Teaching Hospital. 59:162. 357. Jan 2011. 15. Chavez C, Sibbitt WL Jr., Band PA, Chavez-Chiang NR, DeLea SL, Bankhurst AD. Sports Med Arthrosc Rehabil Ther Technol. The Hihgly Accurate Anteriolateral Portal for Injecting the Knee. 3(1). 6. Mar 2011.

16. DeLea SL, Chavez-Chiang NR, Poole JL, Norton HE, Sibbitt WL, Bankhurst AD. Clin Rheumatol. Sonographically Guided Hydrodissection and Corticosteriod Injection for Scleroderma Hand. 30(6). 805- 13. Jun 2011. Epub 2011 Jan 15. 17. Kettwich LS, Sibbitt WL Jr., Chavez-Chiang N, DeLea S, Norton H, Bankhurst A. J Investigative Medicine. Ultrasound-Guided Arthrocentesis of the Knee using New Aspirating Syrine Technologies. 59:162. 265. Jan 2011. 18. Kettwich LS, Sibbitt WL Jr., Chavez-Chiang N, DeLea S, Norton H, Bankhurst A. J Investigative Medicine. Ultrasound-Guided Arthrocentesis of the Knee using New Aspirating Syrine Technologies. 59:162. 265. Jan 2011.

Terry Duclos, M.D., Ph.D. N/A

Roderick Fields, M.D. N/A

Konstantin Konstantinov, M.D. N/A

Wilmer Sibbitt, M.D. 1. Sibbitt WL Jr, Band PA, Chavez-Chiang NR, Delea SL, Norton HE, Bankhurst AD. J. Rheumatol. A Randomized Controlled Trial of the Cost-Effectiveness of Ultrasound-Guided Intraarticular Injection of Inflammatory Arthritis. Epub ahead of print. Nov 2010. 2. Sibbitt RR, Palmer DJ, Sibbitt WL Jr, Bankhurst AD. Cardiovasc Intervent Radio. Image-Directed Fine- needle Aspiration Biopsy of the Thyroid with Safety-engineered Devices. Epud ahead of print. Nov 2010. 3. Haseler LJ, Sibbitt RR, Sibbitt WL Jr, Michael AA, Gasparovic CM, Bankhurst AD. Cardiovasc Intervent Radiol. Syringe and Needle Size, Syringe Type, Vacuum Generation, and Needle Control in Aspiration Procedures. Epub ahead of print. Nov 2010. 4. Ricciardi M, Roldan C, Sibbitt R, Sibbitt W Jr, Michael A, Palmer D. J. Invasive Cardiol. Highly controlled vascular syringes for pericardiocentesis. 22(12). 580-4. Dec 2010. PMID: 21127362 5. Eshaghian A, Kim J, Sibbitt WL Jr, Zlotoff BJ. J Am Acad Dermatol. JAAD Grand Rounds quiz. Chronic urticarial eruption. 63(5). 918-20. Nov 2010. 6. Roldan CA, Joson J, Qualls CR, Sharrar J, Sibbitt WL Jr. Lupus. Premature aortic stiffness in systemic lupus erythematosus by transesophageal echocardiography. 19(14). 1599-605. Dec 2010. PMID: 20813797 7. Jung RE, Caprihan A, Chavez RS, Flores RA, Sharrar J, Qualls CR, Sibbitt W, Roldan CA. BMC Neurol. Diffusion tensor imaging in neuropsychiatric systemic lupus erythematosus. Jul 2010. PMID: 20667115 8. Poole JL, Cordova JS, Sibbitt WL Jr, Skipper B. Am J Occup. Quality of life in American Indian women with arthritis or diabetes. 64(3). 496-505. Jul 2010. PMID: 20608280 9. Gasparovic CM, Roldan CA, Sibbitt WL Jr, Qualls CR, Mullins PG, Sharrar JM, Yamamoto JJ, Bockholt HJ. J Rheumatology. Elevated cerebral blood flow and volume in systemic lupus measured by dynamic susceptibility contrast magnetic resonance imaging. 37(9). 1834-43. Sep 2010. PMID: 20551095 10. Scully M, Anderson B, Lane T, Gasparovic C, Magnotta V, Sibbitt W, Roldan C, Kikinis R, Bockholt HJ. Front Hum Neurosci. An Automated Method for Segmenting White Matter Lesions through Multi-Level Morphometric Feature Classification with Application to Lupus. Jul 2010. PMID: 20428508 11. Brooks WM, Sibbitt WL Jr, Kornfeld M, Jung RE, Bankhurst AD, Roldan CA. Arthritis Rheum. The histopathologic associates of neurometabolite abnormalities in fatal neuropsychiatric systemic lupus erythematosus. 62(7). 2055-63. Jul 2010.

12. DeLea SL, Chavez-Chiang NR, Poole JL, Norton HE, Sibbitt WL, Bankhurst AD. Clin Rheumatol. Sonographically Guided Hydrodissection and Corticosteriod Injection for Scleroderma Hand. 30(6). 805- 13. Jun 2011. Epub 2011 Jan 15. 13. Chavez-Chaing NR, Sibbitt WL Jr., Band PA, DeLea SL, Park KS, Bankhurst AD. Rheumatology Int. The Outcomes and Cost-Effectiveness of Intraarticular Injection of the Rheumatoid Knee. Jan 2011. Epub ahead of Print 14. Chavez C, Sibbitt WL Jr., Band PA, Chavez-Chiang NR, DeLea SL, Bankhurst AD. Sports Med Arthrosc Rehabil Ther Technol. The Hihgly Accurate Anteriolateral Portal for Injecting the Knee. 3(1). 6. Mar 2011. 15. Hayward WAP, Haseler LF, Kettwich LG, Michael AA, Sibbitt WL Jr., Bankhurst AD. Scand J Rheumatol. Pressure Generated by Syringes: Implications for Hydrodissectionand Injection of Dense Connective Tissue Lesions. Apr 2011. Epub ahead of Print 16. Sibbitt WL Jr., Michael AA, Poole JL, Chavez-Chiang Nr, DeLea SL, Bankhurst AD. J Clin Rheumatol. Nerve Blocks at the Wrist for Painful Injections of the Palmar Hand. 17(4). 173-8. Jun 2011. 17. Yaqub S, Ashraf U, Norton H, Gibb JI, Sibbitt WL Jr. Bankhurst AD. J Investigative Medicine. Outcomes and Cost-Effectiveness of Resident Performed Palpation-Guided Intraarticular Procedures in a Teaching Hospital. 59:161. 262. Jan 2011. 18. Kettwich LS, Sibbitt WL Jr., Chavez-Chiang N, DeLea S, Norton H, Bankhurst A. J Investigative Medicine. Ultrasound-Guided Arthrocentesis of the Knee using New Aspirating Syrine Technologies. 59:162. 265. Jan 2011. 19. Ashraf U, Gibb JI, Norton H, Sibbitt WL Jr., Bankhurst AD. J. Investigative Medicine. Outcomes and Cost- Effectiveness of Ultrasound-Guided Procedures Performed in a Teaching Hospital. 59:162. 357. Jan 2011. 20. Norton H, Sibbitt WL Jr., Bankhurst AD, DeLea S, Chavez-Chaing N, Band P. J Investigative Medicine. A Randomized Controlled Trial of Cost-Effectiveness of Ultrasound-Guided Injections of Inflammatory Arthritis. 59:188. 357. Jan 2011. 21. Norton H, Band P, Sibbitt WL Jr., Chavez-Chiang N, DeLea S, Bankhurst AD. J Investigative Medicine. Technique-Based Improvements of Intraarticular Injections for Osteoarthritis of the Knee. 59:188. 358. Jan 2011. 22. Kettwich LS, Sibbitt WL Jr., Chavez-Chiang N, DeLea S, Michael AA, Bankhurst AD. J Investigative Medicine. New Techniquest for Subcutaneous Fat Biopsy. 59:188. 359. Jan 2011. 23. Boyer NM, Roldan C, Yonan KA, Sharrar JM, Sibbitt WL Jr., Greene ER. J Investigative Medicine. Middle Cerebral Artery Resistivity and Pulsatility Indices in Systemic Lupus Erythematosus. 59:188-9. 360. Jan 2011. 24. Sibbitt WL Jr., Kettwich LG, Band PA, Chavez-Chiang NR, DeLea SL, Haseler LJ, Bankhurst AD. Scandinavia J Rheumatol. Does Ultrasound-guidance Improve the Outcomes of Arthrocentesis and Corticoseriod Injection of the Knee?. IN PRESS. Jun 2011.

OUTSIDE SPONSORED RESEARCH

Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total Bankhurst, 10th Annual Rheumatic Non-Mission Amgen, Inc. MED-24679 4/15/2011 4/30/2011 1,304 8,696 10,000 Arthur D. Disease Conference Specific Bankhurst, 10th Annual Rheumatic Non-Mission AP021810/ Abbott Laboratories Inc. 4/1/2011 7/31/2011 1,304 8,696 10,000 Arthur D. Disease Conference Specific Abbott/Bankhurst Bureau of Indian Albuquerque Indian Sibbitt, HHSI242200910057I. Affairs/Department of the Health Services Hospital: Clinical 10/1/2009 9/30/2010 3,273 32,727 36,000 Wilmer L. 0002 Interior Rheumatology Services Albuquerque Indian Sibbitt, Indian Health Health Services Contract- Clinical HHSI242200910057I 10/1/2010 9/30/2011 3,273 32,727 36,000 Wilmer L. Service/DHHS Rheumatology Services

ENDOCRINOLOGY

ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

David S. Schade, MD Professor of Medicine Chief, Division of Endocrinology

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

David S. Schade, M.D., Chief, Division of Endocrinology, continues to be principal investigator for three NIH-funded grants, the Diabetes Prevention Program Outcomes Study (DPPOS), the Epidemiology of Diabetes Intervention and Complications (EDIC), and Type 1 Diabetes TrialNet. He is Vice-Chair, Office of Research, in the Dept of Internal Medicine. He serves as a member of the School of Medicine Research Allocation Committee, and the School of Medicine Research Space Committee.

Reina Villareal, M.D., is Associate Professor of Medicine and Acting Section Chief of Endocrinology at the VAMC. She attends in the VA Bone Clinic and General Endocrinology Clinics. She teaches endocrinology to medical students, residents, and Endocrinology fellows. She attends Endocrine Division meetings, Journal Clubs, and Case Conferences. She spends 50% of her time doing research. She meets regularly with Dr. Schade to review the progress of the VA Endocrinology Division in meeting the missions of the DoIM.

Dr. Richard Dorin is Professor of Medicine & Biochemistry at UNM School of Medicine. Dr. Dorin attends on the inpatient Endocrine Consult Service at the VA all months of the year, and attends on the inpatient Medical Service at the VA one month yearly. Dr. Dorin supervises students, residents, and fellows at two outpatient Endocrine Clinics weekly. He attends and participates in the weekly Endocrine Division case conference, and in monthly journal club and endocrine-pathology conferences.

Dr. Mark Burge contributes to Endocrinology clinical activities by providing one half-day clinic and attending for ten weeks on the endocrine service. He provides exceptional teaching by mentoring medical students, giving lectures in the Endo teaching block, giving fellow didactic conferences, Board Review sessions, and teaching medical residents rotating through endocrinology. He provides research administrative duties as Deputy Director of the Clinical and Translational Science Center.

Dr. Kathleen Colleran is a major contributor to the Endo Division’s clinical care. She has two one half day clinics, Thyroid Ultrasound Clinic once every three weeks, and shares supervision of the Endo Fellow’s clinic Thursday afternoon. She has initiated several research projects as well as undertaking two pharmaceutical studies. Dr. Colleran has an extensive role in Project ECHO, which mandates frequent travel, locally, regionally, and nationally. Additionally, she conducts regular three-day training programs for ECHO trainees.

Dr. Patti Kapsner has one half-day general endocrinology clinics per week, one half day Diabetes Comprehensive Care Center clinic per week and a half day Thyroid Biopsy Clinic with ultrasound guided FNA biopsy of thyroid nodules on a shared basis with Drs. Colleran and Bouchonville. She also attends Fellow Clinic on a shared basis with other faculty members. She also provides endocrine consultative service to her colleagues in other divisions and departments. Additionally she provides care to a large and unique transsexual population, again frequently providing their primary care as well as endocrine care. Dr. Kapsner is the program director for our fellowship program in Endocrinology and plays an integral role in the education of medical students and residents. She lectures and functions as a tutor in the Phase I Endocrinology-Reproductive Medicine block. Dr. Kapsner facilitates the education of Phase II and Phase III medical students and housestaff as they rotate through the required Comprehensive Ambulatory Clerkship and Endocrinology elective and she has received much positive feedback

71 from them. She has also participated as a speaker in several CME events put on by the Department of Internal Medicine and its divisions.

Matthew Bouchonville, M.D., Assistant Professor of Medicine, joined the Endocrinology Division in July 2011. He is Associate Fellowship Program Director and Director of the Inpatient Diabetes Service. He assists in all of the educational functions of the Endocrinology division: didactics, Board Review, Journal Club, Case Conference, etc. He has four half day clinics in the Diabetes Comprehensive Care Center, plus one Endocrinology Clinic. He attends in the Fellow Clinic on a rotating basis with the other endocrine faculty and staffs the Thyroid Biopsy Clinic on a shared schedule with Drs. Kapsner and Colleran. He assisted two fellows in the preparation and submission of their abstracts to the AFMR meeting in Carmel, CA. Their submissions were accepted and published in the Journal of Investigative Medicine in January 2012

 Dr. Kapsner has been a leader in the Department’s diabetes initiatives. She is co-chair of the Diabetes Disease Management Team and plays a pivotal role in the development of UNM’s Diabetes Comprehensive Care Center.  Our second year fellows, Christina Lovate and Corinn Sadler, provided excellent clinical care, as did our first year fellows, Hung Nguyen and Rina Patel-Trujillo. Drs. Lovato and Sadler presented abstracts at American Federation for Medical Research in Carmel, CA in January 2012.  All of the fellows rotate through three months of Bone Clinic, Pediatric Endocrinology Clinic, Reproductive Endocrinology and Metabolic Clinic.  All of the fellows present articles and participate in all monthly meetings of the Journal Club.  All of the faculty members of the Endocrinology Division were listed in the Albuquerque: The Magazine publication for “The ABQ Physicians chosen by fellow docs as the best in their specialties” in March 2012.  All fellows individually prepared and presented an abstract at the American Federation of Medical Research in Carmel, California in January 2012.

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

 Dr. Schade will continue in all of the roles that he has currently undertaken as described in the previous year. He continues to be principal investigator for three NIH-funded grants. He serves as Chief of Endocrinology and Vice Chair for Research in the Dept of Internal Medicine.  Dr. Dorin will continue to direct clinical and teaching activities at the VA. He supervises the VA Cooperative Studies Peptide Resource Facility. He will conduct several pharmaceutical sponsored clinical studies, and continue as Chairman of the VA Animal Research Committee.  Dr. Patti Kapsner will continue patient care and mentor fellows in her Endocrinology Clinics and Thyroid Nodule Clinic. She will also continue as the fellowship director and playing an active role in the education of medical students and residents. She is the Director of the Diabetes Comprehensive Care Center and will continue to provide direction for diabetes care and education for the division, and department, and the new Diabetes Comprehensive Care Center. Additionally she is pursuing additional industry sponsored clinical trials.  For the next fiscal year, Dr. Burge will continue many of his activities in education and clinical service. He is Deputy Director of the Clinical and Translational Science Center.  Dr. Colleran will participate in clinical duties and expand her research activities in Project ECHO and clinical trials.  Dr. Reina Villareal will continue as Acting Endocrine Section Chief, VAMC and will cooperate with Dr. Schade in reviewing the progress of the Endocrinology Section of the VAMC in meeting the missions of the DoIM. She will attend in the VA Bone Clinic and General Endocrinology Clinics. She will continue work on her new R01 grant.  Dr. Bouchonville will continue to assist in all of the educational functions of the Endocrinology division: didactics, Board Review, Journal Club, Case Conference, etc. He will continue his work in the Diabetes Comprehensive Care Center and his Endocrinology Clinic. He will attend in the Fellow Clinic on a rotating

basis with the other endocrine faculty and staff the Thyroid Biopsy Clinic on a shared schedule with Drs. Kapsner and Colleran. He will assist the fellows in the preparation and submission of their abstracts to the AFMR meeting in Carmel, CA.  Our second year fellows, Hung Nguyen and Rina Patel-Trujillo will do both clinical and research rotations.  Our new first year fellows, Kasra Navabi and Justin Jaghab will begin their Endocrine fellowships in July 2012. They will obtain clinical and research experience.

APPOINTMENTS FACULTY Name Title Effective date Matthew Bouchonville, M.D. Ass’t Professor of Medicine 7/1/2011

STAFF None.

SEPARATIONS FACULTY None.

STAFF Lisa Toelle Research Assistant 7/1/12

PUBLICATIONS OF THE DIVISION AND FACULTY

Matthew Bouchonville, M.D. 1. Nguyen H, Bouchonville M, Kapsner P, Colleran K. Management of an unusual case of hypoglycemia. J Invest Medicine. 2012;60(1):139. 2. Patel-Trujillo R, Bouchonville M, Kapsner P, Schade D, Lewiecki M. Undetectable urine calcium in two patients with primary hyperparathyroidism. J Invest Medicine. 2012;60(1):136.

Mark Burge, M.D. 1. Duran-Valdez E, Burge MR, Mata J, Broderick P, Shey L, Valentine V, Schade DS. Is 1,5 Anhydroglucitol (Glycomark) a Clinically Useful Test In Type 1 Diabetes? Diabetes 2011; 60: A245-246. 2. Garimella M, Mitchell S, Burge MR. Effects of Insulin Detemir vs. Insulin Glargine on Food Intake and Satiety factors in Type 1 Diabetes. Diabetes 2011; 60: A687. 3. Burge MR, Mitchell S, Garimella M. Does insulin detemir alter satiety or caloric intake to control weight? Diabetologia 2011; 54(Suppl. 1): S426. 4. Duran-Valdez E, Burge M, Broderick P, Shey L, Valentine V, Schrader R, Schade DS. Insulin Timing: A Beneficial Addition to Intensive Insulin Therapy in Type 1 Diabetes. J Invest Med 2012;60:138. 5. Burge MR, Zamora G, Barriga ES, Chekh V, Luan S, Heintz P, Edwards A, McGrew E, Soliz P. Thermal Functional Imaging for Screening of Peripheral Neuropathy in the Diabetic Foot. Diabetes 2012;61(Suppl.1):A572. 6. Duran-Valdez E, Burge MR, Broderick P, Shey L, Valentine V, Schrader R, Schade DS. Insulin Timing - A Beneficial Addition to Intensive Insulin Therapy in Type 1 Diabetes. Diabetes 2012;61(Suppl.1):A246. 7. Burge MR, Hicks P, Melendrez D. REM Sleep is Impaired in Type 2 Diabetes Patients with Obstructive Sleep Apnea. Diabetes 2012;61(Suppl.1):A201.

8. Kim S, Schneider S, Kravitz L, Mermier C, Burge MR. The Efficacy of Mindfulness-Based Stretching and Breathing Exercise as a Complementary Therapy for Posttraumatic Stress Disorder: A Prospective Randomized Study. Clinical and Translational Science 2012;5:155-156, P77. 9. Colleran K, Aguirre L, Burge MR. Carvedilol vs. metoprolol: A comparison of effects on endothelial function and oxidative stress in response to acute hyperglycemia in patients with type 2 diabetes and hypertension. J Diabetes Mellitus 2012;2(1):146-151. 10. Kong AS, Sussman AL, Yahne C, Skipper B, Burge MR, Davis S. School based Health Center Intervention Improves Body mass Index in Overweight and Obese Adolescents. Clinical and Translational Science 2012; 5:155, P74. 11. Kim S, Burge M. Mindfulness-Based Stretching and Breathing Exercise Reduces Symptoms of Posttraumatic Stress Disorder. BMC Complementary and Alternative Medicine 2012;12:P193.

Kathleen Colleran, M.D. 1. Arora S, Kalishman S, Dion D, Som D, Thornton K, Bankhurst A, Boyle J, Harkins M, Moseley K, Murata G, Komaramy M, Katzman J, Colleran K, Deming P, Yutzy S. (2011b). Quality Profile: Partnering Urban Academic Medical Centers and Rural Primary Care Clinicians to Provide Complex Chronic Disease Care. Health Affairs, 30(6), 1176-1184. 2. Colleran K, Aguirre L, Burge MR Carvedilol vs. Metoprolol: A comparison of effects on endothelial function and oxidative stress in response to acute hyperglycemia in patients with type 2 diabetes and hypertension. Journal of Diabetes Mellitus 2012. 3. Nguyen H, Bouchonville M, Kapsner P, Colleran K. Management of an unusual case of recurrent hypoglycemia in a patient with type 1 diabetes mellitus. 2012 J Invest Medicine 60(1):139. 4. Iwamoto T, Colleran K. Effectiveness of standardization of community healthcare workers with training programs.” Western Medical Student, Resident and Fellow Research Conference. Carmel, California. January 25-28, 2012. (Abstract, oral presentation) 5. Jones B, Iwamoto T, and Colleran K. Assessing physician’s attitudes toward community health care workers as members of the diabetes care team. 6. Colleran K, Aguirre L, Burge MR. Carvedilol vs. metoprolol: A comparison of effects on endothelial function and oxidative stress in response to acute hyperglycemia in patients with type 2 diabetes and hypertension. J Diabetes Mellitus 2012;2(1):146-151.

Richard Dorin, M.D. 1. Dorin RI, Qiao Z, Qualls CR, and Urban FK. Estimation of maximal cortisol secretion rate in healthy humans. J Clin Endocrinol Metab 2012;97(4):1285-1293. 2. Thevenot T, Dorin RI, Monnet E, Qualls CR, Grandclement E, Borot S, Sheppard FM, Weil D, Thibault D, DiMartino V, Kazlauskatie R. High serum levels of free cortisol indicate severity of cirrhosis in hemodynamically stable patients. J Gastroenterol Hepatol 2012;May 31. doi: 10.1111/j.1440- 1746.2012.07188.

R. Eaton, M.D. N/A

Patricia Kapsner, M.D. 1. Lovato C, Kapsner P. A Case of Sternocostoclavicular Hyperostosis Initially Diagnosed as Paget’s Disease of Bone. J Invest Medicine 2012;60(1):136. 2. Sadler C., Kapsner P. An Unusual Case of Tertiary Hyperparathyroidism in a Patient with X-linked Hypophosphatemic Rickets. J Invest Medicine 2012;60(1):136. 3. Rina Patel-Trujillo, Curtis Kapsner, David Schade, Mathew Bouchonville, Patricia Kapsner. Undetectable Urinary Calcium In Two Patients With Primary Hyperparathyroidism. J Invest Medicine 2012;60(1):136- 137.

David Schade, M.D. 1. Klein RL, Carter RE, Jankins AJ, Lyons TJ, Baker NL, Gilbert GE, and the DCCT/EDIC Research Group, incl Schade DS. LDL-containing immune complexes in the DCCT/EDIC cohort: Associations with lipoprotein subclasses. Journal of Diabetes and its complications 25:73-82, 2011. 2. Lopes-Virella MF, Hunt KJ, Baker NL, Lachin J, Nathan DM, Virella G, and the DCCT/EDIC Research Group, incl Schade DS. Levels of oxidized LDL and advanced glycation end products-modified LDL in circulating immune complexes are strongly associated with increased levels of carotid intima-media thickness and its progression in type 1 diabetes. Diabetes 60:582-589, 2011. 3. Lopes-Virella MF, Baker NL, Hunt KJ, Lachin J, Nathan DM, Virella G, and the DCCT/EDIC Research Group, incl Schade DS. Oxidized LDL immune complexes and coronary artery calcification in type 1 diabetes Atherosclerosis 214:462-467, 2011. 4. de Boer IH, Sun W, Cleary PA, Lackin JL, Molitch ME, Steffes MW, et al for the DCCT/EDIC Research Group, incl Schade DS. Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes. The New England Journal of Medicine 365-2366-2376, 2011. 5. Turkbey EB, Backlund JYC, Genuth S, Jain A, Miao C, Cleary PA, et al. for the DCCT/EDIC Research Group, incl Schade DS. Myocardial structure, function and scar in patients with type 1 diabetes. Circulation 124:1737-1746, 2011. 6. Hubbard LD, Sun W, Cleary PA, Danis RP, Hainsworth DP, Peng Q, et al and the DCCT/EDIC Research Group, incl Schade DS. Comparison of digital and film grading of diabetic retinopathy severity in the DCCt/EDIC study. Archives of Ophthalmology 129:718-726, 2011. 7. Gai N, Turkbey EB, Nazarian S, van der Geest RJ, Liu CY, Lima JA, et al for the DCCT/EDIC Research Group, incl Schade DS. Mapping of the gadolinium-enhanced myocardium: Adjustment for for factors affecting interpatient comparison. Magnetic Resonance in Medicine 65:1407-1415, 2011. 8. Wessells H, Penson DF, Cleary P, Rutledge BN, Lachin JM, McVary KT, Schade DS, and the DCCT/EDIC Research Group. Effect of intensive glycemic therapy on erectile function in men with type 1 diabetes. Journal of Urology 185:1828-1834, 2011. 9. de Boer IH, Paterson AD, Brunzell JD for the DCCT/EDIC Research Group, incl Schade DS. Long-term renal outcomes of patients with type 1 diabetes mellitus and microalbuminuria: An analysis of the DCCT/EDIC cohort. Archives of Internal Medicine 171:412-420, 2011. 10. Nathan DM, Steffes MW, Sun W, Rynders GP, Lachin JM for the DCCT/EDIC Research Group, incl Schade DS. Determining stability of stored samples retrospectively: The validation of glycated albumin. Clinical Chemistry 57:286-290, 2011. 11. Sacks DB, Nathan DM, Lachin JM for the DCCT/EDIC Research Group, incl Schade DS. Gaps in the glycation gap hypothesis. Clinical chemistry 57:150-152, 2011. 12. Jacobson AM, Ryan CM, Cleary PA, Waberski BH, Weinger K, Musen G, and the DCCT/EDIC Research Group, incl Schade DS. Biomedical risk factors for decreased cognitive functioning in type 1 diabetes: An 18 year follow-up of the DCCT cohort Diabetologia 54:245-255, 2011. 13. de Boer IH, Paterson AD, Brunzell JD. Reply to letter to editor, “Long-term renal outcomes of patients with type 1 diabetes mellitus and microalbuminuria: An analysis of the DCCT/EDIC, incl Schade DS, cohort,” Archives of Internal Medicine 171:1597, 2011. 14. Polak JF, Backlund JC, Cleary PA, Harrington AP, O’Leary DH, Lachin JM, for the DCCT/EDIC Research Group, incl Schade DS. Progression of carotid artery intima-media thickness during 12 years in the Diabetes Control and Complications (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) study. Diabetes 60:607-613, 2011. 15. Kim C, Edelstein SL, Crandall JP, et al. for the Diabetes Prevention Program research Group, incl Schade DS. Menopause 18(8):857-868, 2011. 16. Boger CA, Chen MH, Tin A, Olden M, Kottgen A, deBoer IH, et al for the DCCT/EDIC Research Group, incl Schade DS. CUBN is a gene locus for albuminuria. J of the Am Society of Nephrology 22:555-570, 2011. 17. Sun L, Dimitromanolakis A, Faye LL, Paterson AD, Waggott D for the DCCT/EDIC Research Group, incl Schade DS. BR-squared: a practical solution to the winner’s curse in genome-wide scans. Human Genetics 129:545-552, 2011. 18. Wang B, Carter RE, Jaffa MA, Nakerakanti S, Lackland D, Lopes-Viretta M, et al for the DCCT/EDIC Research Group, incl Schade DS. J Med Genet 47:391-397, 2011.

19. Majithia AR, Jablonski KA, McAteer JB, Mather KJ, Goldberg RB, Kahn SE, et al. for the DPP Research Group including Schade DS. Association of the SLC30A8 missense polymorphism R325W with proinsulin levels at baseline and after lifestyle, metformin or troglitazone intervention in the diabetes prevention program. Diabetologia [Internet] Jul 21PMID: PMID:21779873, 2011. 20. McCaffery JM, Jablonski KA, Franks PW, Dagogo-Jack S, Wing RR, Knowler WC, et al. for the DPPOS Research group, including Schade DS. TCF7L2 polymorphism, weight loss and proinsulin:insulin ratio in the diabetes prevention program. PLoS ONE [Internet]. 07/26;6(7):e2518, 2011. 21. Florez H, MaY, Crandall JP, Perreault L, Marcovina SM, Bray GA, et al. for the Diabetes Prevention Program Research Group, including Schade DS. Parental longevity and diabetes risk in the diabetes prevention program J Gerontol A Biol Sci Med Sci [Internet]. Nov;66A(11):1211-7; PMID: PMID:21852284, 2011. 22. Larkin ME, Lorenzi GM, Bayless M, Cleary PA, Barnie A, Golden E, et al. and the DCCT/EDIC Research Group incl Schade DS. Evolution of the Study Coordinator Role: The 28 year experience of the DCCT/EDIC. Clinical Trials 2012, E-published June 22. 23. Herman WH, Pop-Busui R, Braffett BH, Martin CL, Cleary PA, Albers JW, et al and the DCCT/EDIC Research Group, incl Schade DS. Use of the Michigan Neuropathy Screening Instrument as a measure of distal symmetrical peripheral neuropathy in Type 1 diabetes: Results from the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC). Diabetic Medicine E-published March 14, 2012. 24. van Koolwijk LME, Ramdas WD, Ikram MK, Jansonius NM, Pasutto F, Hysi PG, et and the DCCT/EDIC Research Group al incl Schade DS. Commmon genetic determinants of intraocular pressure and primary open-angle glaucoma. PLoS Genetics 8:e1002611, 2012. 25. Lopes-Virella MF, Baker NL, Hunt KJ, Lyons TJ, Jenkins AJ, Virella G, and the DCCT EDIC Research Group, incl Schade DS. High concentrations of AGE-LDL and the oxidized LDL in circulating immune complexes are associated with progression of retinopathy in type 1 diabetes. Diabetes Care 35:1333-1340, 2012. 26. Lopes-Virella MF, Carter RE, Baker NL, Lachin J, Virella G, and the DCCT/EDIC Research Group, incl Schade DS. High levels of oxidized LDL in circulating immune complexes are associated with increased odds of developing abnormal albuminuria in Type 1 diabetes. Nephrol Dial Transplant 27:1416-1423, 2012.

Reina Villareal, M.D. N/A

OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

Matthew Bouchonville, M.D. COMMUNITY OUTREACH  Community Outreach – Endo – monthly 7/1/11-6/30/12

Mark Burge, M.D. COMMUNITY OUTREACH  Dr. Burge spent one week in Diabetes Camp for the American Diabetes Association.

PROFESSIONAL AFFILIATIONS  Dr. Burge is a Councilor, Western Society for Clinical Investigation, 2008 to present.

Kathleen Colleran, M.D. COMMUNITY OUTREACH  Dr. Colleran spent one week in Diabetes Camp for the American Diabetes Association.  Community Outreach – Endo – monthly 7/1/11-6/30/12  Grand Rounds in Truth or Consequences, Hatch  Family Medicine Seminar, Taos, NM  Telluride Midwinter Conference, 2/3-5/2012, Telluride, NM

JOURNAL/EDITORIAL REVIEWER  Associate Editor for the Journal of Investigative Medicine.

PROFESSIONAL AFFILIATIONS  Member of the NM Diabetes Advisory committee

Richard Dorin, M.D. COMMUNITY OUTREACH  Community Outreach – Endo – monthly 7/1/11-6/30/12

R. Eaton, M.D. COMMUNITY OUTREACH  Community Outreach – Endo – monthly 7/1/11-6/30/12

Patricia Kapsner, M.D. COMMUNITY OUTREACH  Dr. Kapsner is a regular blood donor to the Albuquerque United Blood Services.

David Schade, M.D. COMMUNITY OUTREACH  Community Outreach – Endo – monthly 7/1/11-6/30/12

Reina Villareal, M.D. COMMUNITY OUTREACH  Community Outreach – Endo – monthly 7/1/11-6/30/12

OUTSIDE SPONSORED RESEARCH

Project Faculty Sponsor Name Project Title type Sponsor Number Start Stop F A Direct Total Colleran, Clinical Trial Agreement- Kathleen Sanofi-Aventis Research Protocol EFC5826 8/30/2006 12/31/2012 45,000 135,000 180,000 Phase III M. Colleran, Corcept Kathleen Therapeutics Clinical Trial - Phase III Research C1073-400 9/30/2008 9/29/2013 12,248 48,994 61,242 M. Incorporated Colleran, Kathleen Veracyte, Inc. Clinical Trial - Phase IV Research VERA001 10/1/2009 9/30/2014 2,125 8,500 10,625 M. Colleran, Corcept Kathleen Therapeutics Clinical Trial Agreement Research C1073-415 4/14/2010 4/13/2015 8,000 32,000 40,000 M. Incorporated Colleran, Kathleen Novartis Clinical Trial Research 11/1/2011 12/31/2012 40,000 M. Colleran, Kathleen Versartis, Inc. Clinical Trial Phase I Research 11VR1.1 4/27/2011 4/26/2016 15,333 61,330 76,663 M. Novartis Kapsner, Pharmaceuticals Clinical Trial - Phase III Clinical CLAF237A23138E1 1/9/2009 7/31/2011 4,430 17,720 22,150 Patricia L. Corporation Kapsner, MannKind Clinical Trial Phase III Research MKCTI-126 8/1/2007 7/31/2012 2,513 10,050 12,563 Patricia L. Corporation Kapsner, Kendle Clinical Trial - Phase II Research TAK-379-201 12/9/2008 12/8/2013 3,441 13,762 17,203 Patricia L. International, Inc. Kapsner, Duke University Clinical Trial - Phase 3 Research 082-00 3/1/2009 2/28/2015 5,000 20,000 25,000 Patricia L. Kapsner, Schering-Plough Clinical Trial Phase 3 Research P04103-3394 3/5/2010 3/4/2015 19,500 78,000 97,500 Patricia L. Kapsner, MannKind Clinical Trial - Phase 3 Research MKC-TI-162 9/17/2010 9/16/2011 2,430 9,720 12,150 Patricia L. Corporation Kapsner, 4422 TECOS Site Duke University Clinical Trial - Phase 3 Research 11/1/2010 2/28/2015 1,700 6,800 8,500 Patricia L. 0479 082-01

Project Faculty Sponsor Name Project Title type Sponsor Number Start Stop F A Direct Total Schade, Pfizer, Inc. Clinical Trial Grant Research Schade/Pfizer 10/1/2010 9/30/2013 0 0 0 David S. University Schade, Hospitals of Clinical Trial Research 123531 1/22/2010 12/31/2011 410 1,642 2,052 David S. Cleveland American The Importance of Schade, Diabetes Insulin Timing in Type 1 Research 7-08-CR-51 7/1/2010 12/31/2011 23,478 156,522 180,000 David S. Association Inc Diabetes Schade, University of Type 1 Diabetes TrialNet Research 161585 7/1/2010 6/30/2011 0 3,610 3,610 David S. South Florida NIH/National Institute of Diabetes Prevention Schade, Diabetes and Program Outcomes Research U01DK048407-18 2/1/2011 1/31/2012 179,345 364,140 543,485 David S. Digestive and Study-Phase 2 Kidney Diseases Epidemiology of Case Western Schade, Diabetes Intervention Reserve Research RES429762 3/1/2011 2/28/2012 55,404 116,535 171,939 David S. and Complications University (EDIC) NIH/National Institute of Diabetes Prevention Schade, U01DK048407-18 Diabetes and Program Outcomes Research 2/1/2011 1/31/2012 17,933 36,415 54,348 David S. REVISED Digestive and Study - Phase 2 (DPPOS) Kidney Diseases Case Western Epidemiology of Schade, Reserve Diabetes Intervention Research RES429762 2/1/2011 6/30/2011 3,767 7,730 11,497 David S. University and Complications

EPIDEMIOLOGY AND PREVENTIVE MEDICINE ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Marianne Berwick, PhD Professor Chief, Division of Epidemiology and Preventive Medicine

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

The following highlights activities of the Division during the 2012 fiscal year.

EDUCATION The Division of Epidemiology and Preventive Medicine has continued to actively teach Medical Students the basics of epidemiologic study design and biostatistics during the year. This program further expands the core medical school curriculum and is led by Dr. Charles Wiggins.

Dr. Marianne Berwick has led the epidemiology educational program in the CTSA’s Master’s of Science in Clinical Research this academic year and Cristina Murray-Krezan has led the biostatistics educational program in the same venue.

A proposal was submitted to HRSA to fund a residency training program in Preventive Medicine with Dr. Kesler as PI and director. This was awarded; two residents were selected from an outstanding pool of applicants, and the program is underway with two more residents added to the program in July, 2012.

RESEARCH AND SCHOLARLY ACTIVITIES Faculty in the Division were involved in a broad array of research endeavors in areas that include cancer, environmental, and occupational health (see faculty grant support).

The division managed a contracts and grants portfolio totaling approximately 1.2 million dollars, excluding those grants managed by contracts and grants personnel in the Cancer Center and the New Mexico Tumor Registry. Grants awarded in the Cancer Center to Division Faculty total approximately 2.2 million dollars. The New Mexico Tumor Registry received continued funding with an award of 14.5 million dollars for a seven year period from the National Cancer Institute.

CLINICAL OPERATIONS Three primary faculty in the Division had clinical responsibilities: Dr. Kesler and Dr. Roeber Rice focused in the area of Environmental/Occupational Medicine and Dr. Hoffman, focused on screening for colorectal and prostate cancer. Dr. Hoffman has an appointment at the VA with his primary home in the Division of Epidemiology and Biostatistics.

HONORS AND AWARDS Dr. Berwick was honored as a Distinguished Professor this year.

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

EDUCATION Dr. Linda Cook and Dr. Marianne Berwick are spearheading an effort to develop a Ph.D. concentration in epidemiology in the BSGP program; they currently have two students in this program and have had several doctoral students “rotate” in either in the “wet lab”, the Molecular Epidemiology Laboratory, or in the “dry lab”, working with Dr. Cook and SEER data.

To support that program they have submitted a training grant application and expect to submit more in the next fiscal year.

RESEARCH AND SCHOLARLY ACTIVITIES Refinement of the organizational structure for cancer prevention and outreach is expected to take place the hiring of faculty in Molecular Epidemiology and Cancer Health Disparities. The Division expects to partner with others in the UNMHSC community to pursue grant funding in the area of health disparities.

APPOINTMENTS

FACULTY Name Title Effective date Herbert Davis, Ph.D. Research Assistant Professor 2/1/2012 (for Bioinformatics) date

STAFF Name Title Effective date Connie Volker Admin Assistant 3 3/14/2012

SEPARATIONS

FACULTY Name Title Effective date John Rushton Research Assistant Professor 8/15/2012

STAFF Name Title Effective date Mark Fischer HS Research Tech 2 6/29/2012

PUBLICATIONS OF THE DIVISION AND FACULTY

Edward Bedrick, Ph.D. 1. Erhardt EB, Rachakonda S, Bedrick EJ, Allen EA, Adali T, and Calhoun VD (2011). Comparison of multi- subject ICA methods for analysis of fMRI data. Human Brain Mapping, 32 (12) :2075-95. PMID 21162045. 2. Kang H, Wilson CS, Harvey RC, Chen IM, Murphy MH, Atlas SR, Bedrick EJ, Devidas M, Carroll AJ, Robinson BW, Stam RW, Valsecchi MG, Pieters R, Heerema NA, Hilden JM, Felix CA, Reaman GH, Camitta B, Winick N, Carroll, WL, Dreyer ZE, Hunger SP, and Willman CL (2011). Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study. Blood. 2011 Dec 30. PMID: 22210879. 3. Ryman SG, Gasparovic C, Bedrick EJ, Flores RA, Marshall AN, and Jung RE (2011). Brain biochemistry and personality: a magnetic resonance spectroscopy study. PLoS One. 6(11):e26758. PMID: 22073190. 4. Ward HH, Brown-Glaberman U, Wang J, Morita Y, Alper SL, Bedrick EJ, Gattone VH, 2nd, Deretic D. and Wandinger-Ness A. (2011) A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1. Mol Biol Cell. 22(18):3289-305. PMID: 21775626. 5. Zahn KL, Wong G, Bedrick EJ, Poston DG, Schroeder TM, and Bauman JE. Relationship of protein and calorie intake to the severity of oral mucositis in patients with head and neck cancer receiving radiation therapy. Head Neck. PMID: 21692134.

6. Kuennen M, Gillum T, Dokladny K, Bedrick EJ, Schneider S, and Moseley PL. (2011). Thermotolerance and heat acclimation may share a common mechanism in humans. Am J Physiol Regul Integr Comp Physiol. 301(2):R524-33. PMID: 21613575. 7. Gasparovic C, Bedrick EJ, Mayer AR, Yeo RA, Chen H, Damaraju E, Calhoun VD, and Jung RE (2011) Test- retest reliability and reproducibility of short-echo-time spectroscopic imaging of human brain at 3T. Magn Reson Med. 66(2):324-32. PMID: 21360748.

Marianne Berwick, Ph.D. 1. Orlow I, Roy P, Reiner AS, Yoo S, Patel H, Paine S, Armstrong BK, Kricker A, Marrett LD, Millikan RC, Thomas NE, Gruber SB, Anton-Culver H, Rosso S, Gallagher RP, Dwyer T, Kanetsky PA, Busam K, From L, Begg CB, Berwick M; for the GEM Study Group. Vitamin D receptor polymorphisms in patients with cutaneous melanoma. Int J Cancer. 2011 PMID: 1365644. 2. Flores KG, Stildey CA, Mackey AJ, Picchi MA, Stabler SP, Siegfried JM, Byers T, Berwick M, Belinsky SA, Leng S; Sex-specific association of sequence variants in CBS and MTRR with risk of promoter hypermethylation in the lung epithelium of smokers. Int J Cancer. 2011 PMID: 1365644. 3. Sondvak VK, Swetter SM, Berwick MA. Gender disparities in patients with melanoma: breaking the glass ceiling. J Clin Oncol. 2012 Jun 20; 30 (18): 2177-8. Epub 2012 Apr 30. No abstract available. PMID: 22547593. 4. Gonzales M, Myers O, Smith L, Olvera HA, Mukerjee S, Li WW, Pingitore N, Amaya M, Burchiel S, Berwick M; ARCH Study Team. Evaluation of land use regression models for NO(2) in El Paso, Texas, USA. Sci Total Environ. 2012 Aug 15;24(2): 432: 135-42. Epub 2012 Jun 21. PMID:22728301. 5. Berwick M. How do solar UV irradiance and smoking impact the diagnosis of second cancers after diagnosis of melanoma?: No answer yet. Dermatoendocrinol. 2012 Jan 1;4 (1): 18-9. PMID: 22870348. 6. Olvera HA, Garcia M, Li WW, Yang H, Amaya MA, Myers O, Burchiel SW, Berwick, M, Pingitore NE Jr. Sci Total Environ. 2012 May 15; 425: 27-34. Epub 2012 March 29. 7. Mukherjee B, Delancey JO, Raskin L, Everett J, Jeter J, Begg CB, Orlow I, Berwick M, Armstromg BK, Kricker A, Marrett LD, Milikan RC, Culver HA, Rosso S, Zanetti R, Kanetsky PA, From L, Gruber SB; GEM Study Investigators. Risk of non-melanoma cancers in first-degree relatives of CDKN2A mutation carriers. J Natl Cancer Inst. 2012 Jun 20; 104 (12): 953-6. Epub 2012 Apr 24. 8. Barnhill RL, Busam KJ, From L, Bagot M, Lugassy C, Berwick M. Inter-observer concordance for the recognition of angiotropism in human melanoma. Pigment Cell Melanoma Res 2011; 24:582-3. PMID: 21466662. 9. Mandelcorn-Monson R, Marrett L, Kricker A, Armstrong BK, Orlow I. Goumas C, Paine S. Rosso S, Thomas N, Millikan RC, Pole JD, Cotignola J, Rosen C, Kanetsky PA, Lee-Taylor J, Begg CB, Berwick M. Sun exposure, vitamin D receptor polymorphisms FokI and BsmI and risk of multiple primary melanoma. Cancer Epidemiol. 2011; 35:e105-10. 10. Berwick M, Begg CB, Armstrong BK, Reiner AS, Thomas NE, Cook LS, Orlow I, Kircker A, Marrett LD, Gruber SB, Anton-Culber H, Millikan RC, Gallagher RP, Dwyer T, Rosso S, Kanetsky PA, Lee-Taylor J. Interaction of CDKN2A and sun exposure in the etiology of melanoma in the general population. J Invest Dermatol 2011;131:2500-3. 11. Satagopan JM, Zhou Q, Oliveria SA, Dusza SW, Weinstock MA, Berwick M, Halpern AC. Properties of preliminary test estimators and shrinkage estimators for evaluating multiple exposures – Application to questionnaire data from the SONIC study. J R Stat Soc Ser C Appl Stat 2011; 60:619-632. 12. Erdei E, Sheng H, Maestas E, Mackey A, White KA, Li L, Dong Y, Taylor J, Berwick M, Morse DE. Self- reported ethnicity and genetic ancestry in relation to oral cancer and pre-cancer in Puerto Rico. PLoS One 2011;6:323950. 13. Olsen CM, Zens MS, Green AC, Stukel TA, Holman CD, Mack T, Elwood JM, Holly EA, Sacerdote C, Gallagher R, Swerdlow AJ, Armstrong BK, Rosso S, Kirkpatrick C, Zanetti R, Bishop JN, Bataille V, Chang YM, Mackie R, Osterlind A, Berwick M, Karagas MR, Whiteman DC. Int J Cancer. Biologic markers of sun exposure and melanoma risk in women: pooled case-control analysis. 129. 713-23. Jul 2011. 14. Murali R, Goumas C, Kricker A, From L, Busam KJ, Begg CB, Dwyer T, Gruber SB, Kanetsky PA, Orlow I, Rosso S, Thomas NE, Berwick M, Scolyer RA, Armstrong BK; For the GEM Study Group. Clinicopathologic

features of incident and subsequent tumors in patients with multiple primary cutaneous melanomas. Ann Surg Oncol 2011 [Epub ahead of print] 15. Lazovich D, Vogel RI, Berwick M, Weinstock MA, Warshoaw EM, Anderson KE. Melanoma risk in relation to use of sunscreen or other sun protection methods. Cancer Epidemiol Biomarkers Prev 2011. [Epub ahead of print] 16. Yue J, Lu H, Liu J, Berwick M, Shen Z. Filamin-A as a marker and target for DNA damage based cancer therapy. DNA Repair (Amst) 2011 [Epub ahead of print] 17. Dusza SW, Halpern AC, Satagopan JM, Oliveria SA, Weinstock MA, Scope A, Berwick M, Geller AC. Prospective study of sunburn and sun behavior patterns during adolescence. Pediatrics 2012;129:309-17.

Linda Cook, Ph.D. 1. Adolphe A, Huang X, Cook LS. Critical Pathways in Cardiology. Carotid Intima-Media Thickness Determined Vascular Age and the Framingham Risk Score. 10. 173-79. Jul 2011. 2. Friedenreich CM, Biel RK, Lau DCW, Csizmadi I, Courneya K, Magliocco AM, Yasui Y, Cook LS. Prev. Case- control Study of the Metabolic Syndrome and Metabolic Risk Factors for Endometrial Cancer. Cancer Epidemiol Biomarkers. 20. 2384-95. Jul 2011. 3. Beesley J, Pickett HA, Johnatty SE, Dunning AM, Chen Q, Li J, Michailidou K, Yi Lu, Rider DN, Palmieri RT, Stutz MD, Lambrechts D, Despierre E, Lambrechts S, Vergote I, Chang-Claude J, Nickels S, Vrieling A, Flesch-Janys D, Wang-Gohrke S, Eilber U, Bogdanova N, Antonenkov N, Runnebaum IB, Dörk T, Goodman MT, Lurie G, Wilkens LR, Matsuno RK, Kiemeney LA, Aben KKH, Marees T, Massuger LFAG, Fridley BL, Vierkant RA, Bandera EV, Olson SH, Orlow I, Rodriguez-Rodriguez L, Cook LS, Le ND, Brooks-Wilson A, Kelemen LE, Campbell I, Gayther SA, Ramus SJ, Gentry-Maharaj A, Menon U, Ahmed S, Baynes C, Pharoah PD, kConFab Investigators, Australian Ovarian Cancer Study Group, ABCTB Investigators, Muir K, Lophatananon A, Chaiwerawattana A, Wiangnon S, Macgregor S, Easton DE, Reddel RR, Goode EL, and Chenevix-Trench G on behalf of the Ovarian Cancer Association Consortium. PLoS One. Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers. 6(9). Sep 2011. Epub 4. Berwick M, Begg CB, Armstrong BK, Reiner AS, Thomas NE, Cook LS, Orlow I, Kricker A, Marrett LD, Gruber SB, Anton-Culver H, Millikan RC, Gallagher RP, Dwyer T, Rosso S, Kanetsky PA, Lee-Taylor J. J Invest Dermatol. Interaction of CDKN2A and Sun Exposure in the Etiology of Melanoma in the General Population. Aug 2011. Epub 5. Biel RK, Csizmadi I, Cook LS, Courneya K, Magliocco AM, Friedenreich, CM. Public Health Nutr. Risk of endometrial cancer in relation to individual nutrients from diet and supplements. 1-13. Jul 2011. Epub 6. Haile RW, John EM, Levine AJ, Cortessis VK, Unger JB, Gonzales M, Ziv E, Thompson P, Spruijt-Metz D, Tucker KL, Bernstein JL, Rohan TE, Ho GY, Bondy ML, Martinez ME, Cook L, Stern MC, Correa MC, Wright J, Schwartz SJ, Baezconde-Garbanati L, Blinder V, Miranda P, Hayes R, Friedman-Jiménez G, Monroe KR, Haiman CA, Henderson BE, Thomas DC, Boffetta P. A review of cancer in U.S. Hispanic populations. Cancer Prev Res 2012;5(2):150-63. PMID:22307564. 7. Olson SH, Atoria CL, Cote ML, Cook LS, Rastogi R, Soslow RA, Brown CL, Elkin EB. The impact of race and comorbidity on survival in endometrial cancer. Cancer Epidemiol Biomarkers Prev. 2012 Mar 16. [Epub ahead of print] PMID:22426148

Kristina Flores, Ph.D. 1. Leng S, Bernauer A, Hong C, Do K, Yingling CM, Flores KG, Tessema M, Tellez CS, Willink R, Burki EA, Picchi MA, Stidley CA, Prados MD, Costello J, Gilliland FD, Crowell RE, Belinsky SA. The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas. Clin Cancer Res. 17(7): 2014-2023, 2011. 2. Flores KG, Stidley CS, Mackey AJ, Picchi MA, Stabler SP, Siegfried JM, Byers T, Berwick M, Belinsky SA, Leng S. Sex-specific association of sequence variants in CBS and MTRR with risk for promoter hypermethylation in non-Hispanic white smokers. Carcinogenesis 33(8):1542-7. Epub, 2012.

Melissa Gonzales, Ph.D. 1. Gonzalez M, Nelson H, Rhyne RL, Stone SN, Hoffman RM. Surveillance of colorectal cancer screening in New Mexico Hispanics and non-Hispanic whites. J Community Health 2012; April 28 [Epub ahead of print] 2. Gonzales M, Myers O, Smith L, Olvera HA, Mukerjee S, Li WW, Pingitore N, Amaya M, Burchiel S, Berwick M; ARCH Study Team. Evaluation of land use regression models for NO(2) in El Paso, Texas, USA. Sci Total Environ. 2012 Aug 15;24(2): 432: 135-42. Epub 2012 Jun 21. PMID:22728301.

Deirdre Hill, Ph.D. 1. Pocobelli C, Voigt L, Beresford S, Hill DA, Chen C, Rossing M, Holmes N, Weiss N. Pregnancy history and risk of endometrial cancer. Epidemiology 2011;22:638-45.. 2. Ziogas A, Horick NK, Kinney AY, Lowery JT Domcheck S, Isaccs C, Griffin CA, Moorman PG, Edwards KL, Hill DA, Berg JS, Tomlinson GE, Strong LC, Anton-Culver H, Finkelstein DM, Plon SE. Clinically Relevant Changes in Family History of Cancer over Time. JAMA 2011;13:172-8. 3. Gammon A, Rothwell E, Simmons R, Lowery JT, Ballinger L, Hill DA ,Kinney AY. Awareness and preferences regarding BRCA1/2 genetic counseling and testing among Latinas and non-Latina white women at increased risk for hereditary breast and ovarian cancer J Genetic Counseling 2011. 4. Phipps AI, Doherty JA, Voigt LF, Hill DA, Beresford SA, Rossing MA, Chen C, Weiss NS. Long-term Use of Continuous-Combined Estrogen-Progestin Hormone Therapy and Risk of Endometrial Cancer. Cancer Causes Control 2011;22:1639-46.

Richard Hoffman M.D., MPH 1. Yee EFT, White R, Lee SJ, Washington DL, Yano EM, Murata G, Handanos C, Hoffman RM. Womens Health Issues. Mental illness. Is there an association with cancer screening in women veterans? 21. 195-202. Jul 2011. 2. Hoffman RM. Screening for Prostate Cancer. N Engl J Med 2011 365; 2013-9. 3. Getrich CM, Sussman AL, Helitzer DL, Hoffman RM, Warner TD, Solares A, Rhyne RL. Qual Health Res. Expressions of machismo in colorectal cancer screening among New Mexico Hispanic sub-populations. Dec 2011. Epub 4. So C, Kirkby KA, Mehta K, Hoffman RM, Powell AA, Freedland SJ, Sirovich B, Yano EM, Walter LC. Medical center characteristics associated with PSA screening in elderly veterans with limited life expectancy. JGIM 2011; Dec 17. [Epub ahead of print]. 5. Gonzalez M, Nelson H, Rhyne RL, Stone SN, Hoffman RM. Surveillance of colorectal cancer screening in New Mexico Hispanics and non-Hispanic whites. J Community Health 2012; April 28 [Epub ahead of print] 6. Hoffman RM. ACP Journal Club (commentary). Vitamin E supplementation increased risk for prostate cancer in health men at a median of 7 years. Ann Intern Med 2012; 156:JC2-3. 7. Hoffman RM. ACP Journal Club (commentary). Periodic PSA-based screening in men 55 to 69 years of age reduce prostate cancer mortality. Ann Intern Med 2012; 157:JC1-4.

Huining Kang, Ph.D. 1. Insuasti-Beltran G, Steidler NL, Kang H and Reichard KK. CD34+ megakaryocytes (>30%) are associated with megaloblastic anaemia and non-acute myeloid neoplasia. Histopathology. 2012 May [Epub ahead of pring]. PMID:22651817 2. Pierce JR, Chang B, Rogers KM, Jernigan JR, Fotieo DR, Kang H and Leverence RR. Redesign of an internal medicine ward rotation: operational challenges and outcome. Journal of Graduate Medical Education, 2012 Mar;4(1):97-100 3. Chen I-M, Harvey RC, Mullighan CG, Gastier-Foster J, Wharton W, Kang H, Borowitz MJ, Camitta BM, Carroll AJ, Devidas M, Pullen DJ, Payne-Turner D, Tasian SK, Reshmi S, Cottrell CE, Reaman GH, Bowman WP, Carroll WL, Loh ML, Winick NJ Hunger SP and Willman CL. Outcome modeling with CRLF2, IKZF1, JAK and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children’s Oncology Group Study. Blood, 2012 Apr 12; 119(15):3512-22. PMCID: PMC3325039 4. Chen J, Young SM, Allen C, Seeber A, Peli-Guiil MP, Panchaud N, Waller A, Ursu O, Yao T, Golden J, Strouse JJ, Carter MB, Kang H, Foutz T, Bologa CG, Edwards B, Peterson BR, Aube J, Werner-Washburne M,

Loewith R, de Virgilio C, Sklar LA. Identification of a small molecule yeast TORC1 inhibitor with flow cytometry based multiplex screen. ACS Chem Biol. 2012 Jan 19 [Epub ahead of print] 5. Kang H, Wilson CS, Harvey RC, Chen IM, Murphy MH, Atlas SR, Bedrick EJ, Devidas M, Carroll AJ, Robinson BW, Stam RW, Valsecchi MG, Pieters R, Heerema NA, Hiden JM, Felix CA, Reaman GH, Camitta B, Winick N, Carroll WL, Dreyer ZE, Hunger SP, Willman CL. Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children’s Oncology Group study. Blood, 2011 Dec 20 [Epub ahead of print] 6. Reichard KK, Kang H, Robinett S. Pediatric B-lymphoblastic leukemia with RUNX1 amplification: Clinicopathologic study of eight cases. Mod Pathol. 2011 Dec; 24(12):1606-11

Irena King, Ph.D. 1. Sampath H, Batra AK, Vartanian V, Carmical JR, Prusak D, King IB, Lowell B, Earley LF, Wood TG, Marks DL, McCullough AK, R Stephen L. Variable penetrance of metabolic phenotypes and development of high-fat diet-induced adiposity in NEIL1-deficient mice. Am J Physiol Endocrinol Metab. 300(4):E724-34, 2011. 2. Kristal A, Till C, Platz E, Song X, King IB, Neuhouser M, Ambrosone C, and Thompson I, Jr. Serum lycopene concentration and prostate cancer risk: Results from the Prostate Cancer Prevention Trial. CEBP 20 (4):638-46, 2011. 3. Brasky TM, White E, Neuhouse ML, Thompson IM, King IB, Song X, Till C, Alan R. Kristal AR, and P01 investigators contributing substantially to data analysis or interpretation. Serum Phospholipid Fatty Acids and Prostate Cancer Risk: Results from the Prostate Cancer Prevention Trial. American Journal of Epidemiology. 173(12):1429-39, 2011. 4. Cheng TY. Barnett MJ. Kristal AR. Ambrosone CB. King IB. Thornquist MD. Goodman GE. Neuhouser ML. Genetic Variation in Myeloperoxidase Modifies the Association of Serum {alpha}-Tocopherol with Aggressive Prostate Cancer among Current Smokers. Journal of Nutrition. 141(9):1731-7, 2011 Sep. 5. Mozaffarian D. Lemaitre RN. King IB. Song X. Spiegelman D. Sacks FM. Rimm EB. Siscovick DS. Circulating Long-Chain {omega}-3 Fatty Acids and Incidence of Congestive Heart Failure in Older Adults: The Cardiovascular Health Study: A Cohort Study. Annals of Internal Medicine. 155(3):160-70, 2011. 6. Lemaitre RN. Tanaka T. Tang W. Manichaikul A. Foy M. Kabagambe EK. Nettleton JA. King IB. Weng LC. Bhattacharya S. Bandinelli S. Bis JC. Rich SS. Jacobs DR Jr. Cherubini A. McKnight B. Liang S. Gu X. Rice K. Laurie CC. Lumley T. Browning BL. Psaty BM. Chen YD. Friedlander Y. Djousse L. Wu JH. Siscovick DS. Uitterlinden AG. Arnett DK. Ferrucci L. Fornage M. Tsai MY. Mozaffarian D. Steffen LM. Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium. PLoS Genetics. 7(7):e1002193, 2011. 7. Takata Y, Kristal AR, King IB, Song X, Diamond AM, Foster CB, Hutter CM, Hsu L, Duggan DJ, Langer RD, Petrovitch H, Shikany JM, Vaughan TL, Lampe JW, Prentice RL, Peters U. Serum Selenium, Genetic Variation in Selenoenzymes, and Risk of Colorectal Cancer: Primary Analysis from the Women's Health Initiative Observational Study and Meta-analysis. Cancer Epidemiol Biomarkers Prev 20(9):1822-30, 2011. 8. Djousse L. Biggs ML. Lemaitre RN. King IB. Song X. Ix JH. Mukamal KJ. Siscovick DS. Mozaffarian D. Plasma omega-3 fatty acids and incident diabetes in older adults. American Journal of Clinical Nutrition. 94(2):527-33, 2011. 9. Wu JH. Lemaitre RN. Imamura F. King IB. Song X. Spiegelman D. Siscovick DS. Mozaffarian D. Fatty acids in the de novo lipogenesis pathway and risk of coronary heart disease: the Cardiovascular Health Study. American Journal of Clinical Nutrition. 94(2):431-8, 2011. 10. Navarro SL. Chen Y. Li L. Li SS. Chang JL. Schwarz Y. King IB. Potter JD. Bigler J. Lampe JW. UGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and Vegetables. Drug Metabolism & Disposition. 39(9):1650-7, 2011 Sep. 11. Lemaitre RN, Sitlani C, Song X, King IB, McKnight B, Spiegelman D, Sacks FM, Djoussé L, Rimm EB, Siscovick DS, Mozaffarian D. Circulating and dietary α-linolenic acid and incidence of congestive heart failure in older adults: the Cardiovascular Health Study.Am J Clin Nutr. 2012 Aug;96(2):269-74. Epub 2012 Jun 27. PMID: 22743310 [PubMed - in process] 12. Takata Y, Kristal AR, Santella RM, King IB, Duggan DJ, Lampe JW, Rayman MP, Blount PL, Reid BJ, Vaughan TL, Peters U. Selenium, selenoenzymes, oxidative stress and risk of neoplastic progression from Barrett's

esophagus: results from biomarkers and genetic variants. PLoS One. 2012;7(6):e38612. Epub 2012 Jun 8.PMID: 22715394 [PubMed - in process] 13. Wu JH, Lemaitre RN, King IB, Song X, Sacks FM, Rimm EB, Heckbert SR, Siscovick DS, Mozaffarian D. Association of plasma phospholipid long-chain ω-3 fatty acids with incident atrial fibrillation in older adults: the cardiovascular health study. Circulation. 2012 Mar 6;125(9):1084-93. doi: 10.1161/CIRCULATIONAHA.111.062653. Epub 2012 Jan 26.PMID: 22282329 [PubMed - indexed for MEDLINE] 14. Takata Y, King IB, Lampe JW, Burk RF, Hill KE, Santella RM, Kristal AR, Duggan DJ, Vaughan TL, Peters U. Genetic variation in GPX1 is associated with GPX1 activity in a comprehensive analysis of genetic variations in selenoenzyme genes and their activity and oxidative stress in humans. J Nutr. 2012 Mar;142(3):419-26. Epub 2012 Jan 18.PMID: 22259188 [PubMed - indexed for MEDLINE]

Sang-Joon Lee, Ph.D. 1. Bauman J, Verschraegen CF, Belinsky S, Muller C, Rutledge T, Fekrazad M, Ravindranathan M, Lee S-J, Jones D. A Phase I study of 5-Azacytidine and Erlotnib in Advanced Solid Tumor Malignancies. Cancer Chemotherapy and Pharmacology, 69 (2): 547-554, 2011 2. Verschraegen CF, Arias-Pulido H, Lee S-J, Movva S, Cerilli LA, Eberhardt S, Schmit B, Quinn R, Muller CY, Rabinowitz I, Purdy M, Snyder D, Bocklage T. Phase IB Study of the Combination of Docetaxel, Gemcitabine, and Bevacizumab in Patients with Advanced or Recurrent Soft Tissue Sarcoma the Axtell Regimen. Annals of Oncology (published on line doi: 10.1093/annonc/mdr299, Vol and page numbers will be available later), 2011 3. Armien B, Pascale JM, Munoz C, Lee S-J, Choi KL, Avila M, Broce C, Armien A, Gracia F, Hjelle B, Koster F. Incidence Rate for Hantavirus Infections without Pulmonary Syndrome, Panama. Emerging Infectious Diseases. 17 (10): 1936-1939, 2011 4. Ravi-Kumar S, Lee S-J, Rabinowitz I, Verschraegen C-F. Does Ethnicity Influence Response To Docetaxel Based-Chemotherapy For Patients With Castration Resistant Prostate Cancer? The New Mexico Perspective. The Internet Journal of Oncology. 7 (2), 2011 5. Yee EF, White R, Lee S-J, Washington DL, Yano EM, Murata G, Handanos C, Hoffman RM. Mental Illness: Is there an Association With Cancer Screening Among Women Veterans? Women’s Health Issues. 21(4): 195-202, 2011 6. Ravi-Kumar S, Lee S-J, Rabinowitz I, Verschraegen CF. Does Ethnicity Influence Response To Docetaxel Based-Chemotherapy For Patients With Castration Resistant Prostate Cancer? The New Mexico Perspective. The Internet Journal of Oncology. Volume 7 Number 2, 2011

Julie Lovchik, Ph.D. 1. Chen Z, Schneerson R, Lovchik J, Lyons CR, Zhao H, Dai Z, Kubler-Kielb J, Leppla SH, Purcell RH. 2011. Pre- and postexposure protection against virulent anthrax infection in mice by humanized monoclonal antibodies to Bacillus anthracis capsule. Proc Natl Acad Sci U S A. 108(2):739-44. 2. Lovchik, J.A., M. Drysdale, T.M. Koehler, J.A. Hutt, C.R. Lyons. 2012. Expression of either Lethal Toxin or Edema Toxin alone is Sufficient for B. anthracis Virulence in a Rabbit Model of Inhalational Anthrax. Infect Immun. 80:2414-2425 3. Peachman, KK, Li, Qin, Matyas, GR, Shivachandra, SB, Lovchik, JA, Lyons, RC, Carl R. Alving, Rao, VB, and Rao, M. Anthrax vaccine antigen-adjuvant formulations completely protect New Zealand white rabbits against challenge with Bacillus anthracis Ames strain spores. Clin Vaccine Immunol. 2012 Jan;19(1):11-6

Li Luo, Ph.D. 1. Luo L., Xu L., Jung R., Pearlson G., Adali T., Calhoun V. 2012, Constrained Source Based Morphometry Identifies Structural Networks Associated with Default Mode Network. Brain Connectivity, [Epub ahead of print] 2. Luo L., Boerwinkle E. and Xiong M. 2011, Association studies for next-generation sequencing. Genome Research, 21: 1099-1108.

Cristina Murray-Krezan, B.A., M.S. 1. Rayburn WF, Klagholz JC, Murray-Krezan C, Dowell LW, Strunk AL, Distribution of American Congress of Obstetricians and Gynecologists Fellows and Junior Fellows in Practice in the United States, Obstet Gynecol. 2012 May; 119(5):1017-22. PMID: 22525913 2. Posse S, Ackley E, Mutihac R, Rick J, Shane M, Murray-Krezan C, Zaitsev M, Speck O, Enhancement of temporal resolution and BOLD sensitivity in real-time fMRI using multi-slab echo-volumar imaging, NeuroImage. 2012 Feb 28. [Epub ahead of print]. PMID: 22398395 3. Stippler M, Smith C, Carlson A, Morley S, Murray-Krezan C, Kraynik, J, Kennedy G, Utility of Routine Follow-up Head CT after Mild Traumatic Brain Injury: A Systematic Review of the Literature, Emerg Med J. 2012 Feb 3. [Epub ahead of print]. PMID 22307924

Orrin Myers, Ph.D. 1. Chabot-Richards D, Martin D, Myers OB, Czuchlewski DR and Hunt KE. 2011. Quantitative Image Analysis in the Assessment of Diffuse Large B-cell Lymphoma. Modern Pathology 24, 1598-1605 (December 2011) 2. Olvera HA, Garcia M, Wen-Whai L, Yang H, Amaya MA, Myers OB, Burchiel SW, Berwick M, Pingitore NE, Jr. 2012. Principal component analysis optimization of a PM2.5 land use regression model with small monitoring network. Science of the Total Environment 425:27-34. 3. Gonzales M, Myers OB, Smith L, Olvera HA, Mukerjee S, Li WW, Pingitore N, Amaya M, Burchiel S, Berwick M; ARCH Study Team. Evaluation of land use regression models for NO(2) in El Paso, Texas, USA. Sci Total Environ. 2012 Aug 15;24(2): 432: 135-42. Epub 2012 Jun 21. PMID:22728301.

Heidi Roeber Rice, M.D. 1. Roeber Rice H, Varkey P. What Immunizations Should I Offer to My Patients? A Primer on Adult Immunizations. JAPI 2011 59:568-572 2. McGovern P, Dagher R, Roeber Rice H, Gjerdingen D, Dowd B, Ukestad L, Lundberg U. A Longitudinal Analysis of Total Workload and Women’s Health after Childbirth. JOEM 2011 53(5):497-505 3. Baker B, Roeber Rice H, Bartels M. Phenoxyacetic Acid Herbicides. In: H.E. Hoffman, R.B. Palmer & S. Phillips (Eds.), Clinical Practice of Biological Monitoring (pp. 179-185). Beverly Farms, MD: OEM Press, 2012 4. Haddad L, Khu HN, Bayingana R, Roeber Rice H, Strunk S, Allen S. Integration of couples’ voluntary counseling and testing and family planning in Kigali, Rwanda. Contraception 2011 84(3): 324

Christine Stidley, Ph.D. 1. Leng S, Stidley CA, Liu Y, Edlund CK, Willink RP, Han Y, Landi M, Thun M, Picchi MA, Bruse SE, Crowell RE, Van Den Berg , Caporaso NE< Amos CI, Siegfried JM, Tesfaigzi Y, Gilliland FD, Belinsky SA. Genetic determinants for promoter hypermethyation in the lungs of smokers: A candidate gene-based study. Cancer Research. 2012;72(3):707-715.

Charles Wiggins, Ph.D. 1. Wu X-C, Eide MJ, King J, Saraiya M, Huang Y, Wiggins CL, Barnholtz-Sloan JS, Cokkinides V, Miller J, Patel P, Ekwueme D, Martin N, Kim J. Racial and Ethnic Variations in Incidence and Survival of Cutaneous Melanoma in the United States, 1999-2006. Journal of the American Academy of Dermatology 2011: 65:S26-S37. 2. Jemal A, Saraiya M, Patel P, Cherala SS, Barnholtz-Sloan J, Kim J, Wiggins CL, Wingo PA. Recent Trends in Cutaneous Melanoma Incidence and Death Rates in the United States, 1992-2006. Journal of the American Academy of Dermatology 2011: 65:S17-S25. 3. Geppert C, Arndell C, Clithero A, Dow-Velarde L, Eldredge J, Kalishman S, Kaufman A, McGrew M, Snyder T, Solan B, Timm C, Wagner L, Wiese W, Wiggins CL, Cosgrove E. Learning to Be Leaders: The University of New Mexico School of Medicine Public Health Certificate. American Journal of Preventive Medicine 2011; 41 (4 Supplement 3): S214-219. 4. Shah SK, Fleet TM, Williams V, Smith AY, Wiggins CL. SEER Underestimates the Incidence of Positive Surgical Margins at Radical Prostatectomy: Results of a Systematic Audit. Urology 2011; 186: 855-859.

5. Nir I, Wiggins CL, Morris K, Rajput A. Diversification and trends in biliary tree cancer among the three major ethnic groups in the state of New Mexico. American Journal of Surgery. Published on-line December 27, 2011.

Janice Yager, Ph.D. 1. Clewell HJ, Thomas RS, Kenyon EM, Hughes MF, Adair BM, Gentry PR, Yager JW. Concentration- and time- dependent genomic changes in the mouse urinary bladder following exposure to arsenate in drinking water for up to twelve weeks. (2011).Toxicological Sciences 123(2):421-32. 2. Yager JW, Efremenko A, Black M, Thomas RS, McKim J, Wilga PC, Arnold LL, Gentry PR, Clewell HJ. Genomic changes in primary human uroepithelial cells following 24-hour exposure to mixtures of arsenite and its principal methylated metabolites. Abstract 110. (2011) Environmental and Molecular Mutagenesis 52(S1):S68. 3. Balbuena P, Clewell R, Efremenko A, Pluta L, Black M, Gentry PR, Clewell HJ, Yager JW. A novel approach to assess NQ01 responses to arsenic utilizing a human uroepithelial primary cell culture system. Abstract 111. (2011) Environmental and Molecular Mutagenesis 52(S1):S68. 4. Yager JW, Clewell HJ, Efremenko A, Black M, Thomas RS, Wagner H, Wilga PC, McKim JM, Arnold LL, Gill G, Gentry PR. Genomic changes in human primary uroepithelial cells following exposure to arsenic mixtures. Abstract. (2011) The Toxicologist 120(S2):S559.

OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

Edward Bedrick, Ph.D. JOURNAL/EDITORIAL REVIEWER  Associate Editor, The American Statistician  Associate Editor, Journal of Statistics

Marianne Berwick, Ph.D. INVITED LECTURES: REGIONAL OR NATIONAL Ad hoc reviewer or editorial consultant  American Journal of Epidemiology  Archives of Dermatology  Archives of Internal Medicine  British Journal of Dermatology  British Medical Journal  Cancer  Cancer Causes and Control  Cancer Epidemiology, Biomarkers and Prevention  DNA Repair  International Journal of Cancer  Journal of the American Medical Association  Journal of Investigative Dermatology  Journal of the National Cancer Institute  Melanoma Research  Mutagenesis  Photobiology and Photochemistry  Pigment Cell and Melanoma Research

EDITORIAL BOARD  Cancer Epidemiology, Biomarkers and Prevention – current Cancer – current

GRANT REVIEWER  NCI Scientific Review Group Member – Subcommittee A – 2008 to 2013  NIH – Innovator Awards - 2011

PROFESSIONAL AFFILIATIONS  American Association for Cancer Research/Molecular Epidemiology Group  Society for Epidemiologic Research  American College of Epidemiology, Fellow  American Society for Preventive Oncology  American Society for Photobiology  Society for Investigative Dermatology

Linda Cook, Ph.D. AD HOC REVIEWER OR EDITORIAL CONSULTANT  American Journal of Epidemiology  Archives of Pediatrics and Adolescent Medicine  Cancer, Causes and Control  Canadian Journal of Public Health  Cancer Epidemiology, Biomarkers and Prevention  Chronic Diseases in Canada  Canadian Medical Association Journal  Epidemiology  European Journal of Cancer  International Journal of Cancer  International Journal of Epidemiology  Journal of the American Medical Association  Journal of the National Cancer Institute  Alberta Cancer Foundation  Canadian Institutes of Health Research (various grant review committees)  British Columbia Workers Compensation Board  British Columbia Health Research Foundation  Randomized Controlled Trial Review Panel  Reader’s Digest Health Books

GRANT REVIEWER  Member, Career Catalyst Research Application, Pre-Application Review, Susan B. Komen for the Cure, Dallas, Texas.  Member, Post-Baccalaureate Training in Disparities Research (PBT-DR) grant review panel, Susan B. Komen for the Cure, Dallas, Texas

PROFESSIONAL AFFILIATIONS  Society for Epidemiologic Research (SER)  American Public Health Association (APHA)  Canadian Society for Epidemiology and Biostatistics (CSEB)  American Association for Cancer Research (AACR)

Kristina Flores, Ph.D. PROFESSIONAL AFFILIATIONS  American Association for Cancer Research

Deirdre Hill, Ph.D. JOURNAL/EDITORIAL REVIEWER  Blood  JAMA  American Journal of Epidemiology  Archives of Internal Medicine  International Journal of Cancer  Cancer  Cancer Causes and Control  Cancer Epidemiology Biomarkers Prevention  BMC Cancer  Molecular Carcinogenesis  Obstetrics and Gynecology  American Journal of Obstetrics/Gynecology  Maturitas  Journal of Clinical Oncology

PROFESSIONAL AFFILIATIONS  Society for Epidemiologic Research  American Association for Cancer Research Molecular Epidemiology Working Group, American Association for Cancer Research

Richard Hoffman M.D., MPH AD HOC REVIEWER OR EDITORIAL CONSULTANT  ACP Journal Club  American College of Cardiology Foundation 2011 Clinical Expert Consensus Document on Practical Clinical Considerations in the Interpretation of Troponin Elevations.  American College of Physicians’ Education and Information Resource  American College of Physicians MKSAP 16 Disorders of the Liver  American College of Physicians MKSAP 16 General Internal Medicine  American Journal of Pharmacy Benefits  American Journal of Preventive Medicine  Annals of Family Medicine  Annals of Internal Medicine  Archives of Internal Medicine  Asian Journal of Andrology  BMC Urology  British Cancer Journal  Cancer Causes and Control  Cleveland Clinic Journal of Medicine  Clinical Investigation  Digestive Diseases and Science  Ethnicity and Disease  Expert Opinion on Biological Therapy  Expert Review of Gastroenterology and Hepatology  Health Services Research Journal  Journal of Aging Research  Journal of Clinical Epidemiology  Journal of Clinical Outcomes Medicine  Journal of General Internal Medicine  Journal of the American Geriatrics Society

 Journal of the American Medical Association  Journal of the National Cancer Institute  Journal of Urology  Medical Care  Medical Letter  Nature Clinical Practice Oncology  New England Journal of Medicine  Nutrition  Preventive Medicine  Prostate Cancer and Prostatic Diseases  Spine  UpToDate®  Urologic Oncology

JOURNAL/EDITORIAL REVIEWER  Associate Editor, American College of Physicians Journal Club  Deputy Editor, Journal of General Internal Medicine  Article Consultant, Interpretation of the Medical Literature Project, National Board of Medical Examiners

EDITORIAL BOARD  Editorial Board, The Medical Round Table

PROFESSIONAL AFFILIATIONS  American Urological Association (Affiliate)  Western Society of Clinical Investigators  Society of General Internal Medicine  American College of Physicians

Huining Kang, Ph.D. PROFESSIONAL AFFILIATIONS  American Association for Cancer Research  American Society of Hematology  American Statistical Association  Association of Chinese-American Engineers and Scientists, New Mexico Chapter  Association of Chinese Agricultural Applied Mathematics

Sang-Joon Lee, Ph.D. JOURNAL/EDITORIAL REVIEWER  Peer View Institute for Medical Education

PROFESSIONAL AFFILIATIONS  American Statistical Association (ASA)  Institute of Mathematical Statistics (IMS)  International Biometric Society, Eastern North American Region (ENAR)  American Association for Cancer Research (AACR)

Li Luo, Ph.D. PROFESSIONAL AFFILIATIONS  American Statistical Association  American Society of Human Genetics

Cristina Murray-Krezan, B.A., M.S. PROFESSIONAL AFFILIATIONS  American Statistical Association  Society for Clinical Trials  Western North American Region of the International Biometrics Society

Heidi Roeber Rice, M.D. PROFESSIONAL AFFILIATIONS  American College of Occupational and Environmental Medicine  Delegate, ACOEM House of Delegates, Education Section Representative  American College of Preventive Medicine  American Medical Association  Association for Prevention Teaching and Research  Rocky Mountain Academy of Occupational and Environmental Medicine

Christine Stidley, Ph.D. GRANT REVIEWER  Special Emphasis Panel for PAR 10-283: Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts

PROFESSIONAL AFFILIATIONS  American Statistical Association  International Biometric Society  Society for Epidemiologic Research

Charles Wiggins, Ph.D. INVITED LECTURES: REGIONAL OR NATIONAL  Wiggins CL. Cancer Causes and Control. Presented at the 2011 Navajo Nation Cancer Conference. Window Rock, Arizona. July 12, 2011.  Wiggins CL. A Brief Introduction to Cancer in Indian Country. Presented at the Southwest Tribal Institutional Review Board Workshop. Isleta Pueblo, New Mexico. August 17, 2011.

AD HOC REVIEWER OR EDITORIAL CONSULTANT  American Journal of Epidemiology  American Journal of Preventive Medicine  Annals of Epidemiology  Cancer  Cancer, Epidemiology, Biomarkers and Prevention  Cancer Research  Epidemiology  Ethnicity and Disease  International Journal of Circumpolar Health  Journal of Cancer Education  Journal of Investigative Dermatology

PROFESSIONAL AFFILIATIONS  Society for Epidemiologic Research  American Association for the Advancement of Science

OUTSIDE SPONSORED RESEARCH

Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total

See UNM Cancer Center report for information on cancer-related the grants awarded to PIs within the Division

ARRA: Air Pollution, Systemic Inflammation, Berwick, University of Texas, El and Sub-Clinical Research 26-1409-49-61 9/19/2009 7/31/2011 12,445 24,890 37,335 Marianne Paso Atherosclerosis in High- Altitude Children ARRA: Air Pollution, Systemic Inflammation, Berwick, University of Texas, El and Sub-Clinical Research 26-1409-49-61 8/1/2010 7/31/2011 12,721 25,442 38,163 Marianne Paso Atherosclerosis in High- Altitude Children NIH/National Institute Gonzales, Gene-environment Cancer of Environmental Research 5K01ES014003-05 8/1/2010 7/31/2011 0 0 0 Melissa Risks in Melanoma (NCE) Health Sciences Foundation for Hoffman, Non-Mission Informed Medical Medical Editor 0102-5 7/1/2011 6/30/2012 5,075 29,850 34,925 Richard Specific Decision Making HRSA-Health Radiation Exposure Kesler, Resources and H1GRH00007-09- Screening and Education Clinical 9/1/2011 8/31/2012 45,766 189,222 234,988 Denece Services 00 Program Administration Lovelace Respiratory Kesler, Lovelace Respiratory Research Institute - Clinical PSA-11-13 5/1/2011 4/30/2012 0 6,000 6,000 Denece Research Institute Consulting Services Lovelace Respiratory Kesler, Lovelace Respiratory Research Institute - Clinical PSA-11-14 5/1/2011 4/30/2012 0 75,000 75,000 Denece Research Institute Occupational Medicine Services Development of a Medical Kesler, Johns Hopkins Screening Program for 2000070550 Clinical 2/1/2011 1/31/2012 0 0 0 Denece University Former Sandia and LANL Amend 3/4/5 Workers (NCE) HRSA-Health Kesler, Resources and 2011 Preventive Medicine D33HP19042-01- Education 7/1/2011 6/30/2012 26,529 432,632 459,161 Denece Services Residency Program 01 Administration

Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total Honeywell Aerospace of Kesler, Honeywell Non-Mission Albuquerque - Clinician PSA-11-04 5/1/2011 4/30/2012 0 2,500 2,500 Denece Corporation Specific Services Mechanisms of Energy Fred Hutchinson King, Balance and Cancer Cancer Research Research 680903 9/1/2010 8/31/2011 0 0 0 Irena B. Prevention, TREC project 5 Center (NCE) Multi-level Intervention to Fred Hutchinson King, Prevent Obesity in Low Cancer Research Research 716929 6/10/2011 5/31/2012 9,647 18,917 28,564 Irena B. Income Working Adults Center (TREC Coordination Center) Human Genetic Variation in King, University of Fatty Acid Metabolism and Research 613016 1/1/2011 12/31/2011 28,689 57,377 86,066 Irena B. Washington Sudden Cardiac Arrest Task E09 Validation of Pan- Species ELISAs to Detect Stidley, Lovelace Respiratory Antibodies to F1 and V Christine Research JK090139 8/1/2010 7/31/2011 0 0 0 Research Institute Antigens for Use in Vaccine Aileen Clinical Trial and Non- clinical Studies (NCE) Stidley, Lovelace Biomedical Genetic and Epigenetic JK090153/Project3 Christine & Environmental Biomarkers of Squamous Research 7/1/2011 6/30/2012 6,190 23,810 30,000 360111 Aileen Research Institute Cell Carcinoma of the Lung Stidley, Lovelace Respiratory Statistical Support for Lung Christine Research JK100263 10/1/2011 9/30/2012 12,381 47,619 60,000 Research Institute Cancer Program Aileen Pilot Study of Arsenic, UV Yager, NIH/National R21ES018705- and Melanoma in a Non- Research 8/10/2010 7/31/2011 75,875 150,000 225,875 Janice W. Institutes of Health 01A1 Hispanic White Population Pilot Study of Arsenic, UV Yager, NIH/National and Melanoma in a Non- R21ES018705- Research 8/10/2010 7/31/2011 0 0 0 Janice W. Institutes of Health Hispanic White Population 01A1 (NCE)

GASTROENTEROLOGY AND HEPATOLOGY

ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Thomas Y. Ma, MD, PhD, FACG Professor of Medicine, Cell Biology and Physiology Chief, Division of Gastroenterology and Hepatology

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

During the past academic year (July 1, 2011 – June 30, 2012), UNM Gastroenterology and Hepatology Division has made many important and significant advances in all academic areas including research, clinical, and educational activities. The G.I. Fellowship Training Program continues to improve with changes to further emphasize education and training. The research programs have been greatly enhanced with increases in grant funding and expansion of the basic science research program, and the divisional clinical productivity has remained at a very high level during the review period.

The UNM G.I. Division research investigators had an outstanding year as evidenced by over 33 research publications and over $26.6 million dollars in total NIH, VA, and federal government supported research funding.

EDUCATION For the tenth year in a row, top two percentile of the fellowship applicants were matched into our fellowship program. This emphasizes the highest quality of fellows in our training program and is further evidence of the excellent progress the Division has made in providing an excellent training program. The G.I. fellowship training and education program has been completely overhauled during the past nine years to optimize the training and education experience of the G.I. fellows and rotating residents. During the past ten years, the total fellowship positions have been increased from 5 to 12 positions. The increase in the number of fellowship positions has decreased the clinical service burden and increased the training opportunity. The gastroenterology teaching conferences have been revised and upgraded. Thursday afternoons (4-5 hours) have been designated strictly for educational conferences. The core curriculum conferences are held on a weekly basis and cover the core topics in gastroenterology. The weekly core curriculum module is moderated by a faculty member having an expertise in the selected disease topic. Over the three year fellowship training program all relevant core topics in G.I. are covered. In addition, Journal Club, Research Conferences, Clinical Case Conferences, Pathology Case Discussions, Multidisciplinary Pancreaticobiliary Diseases and Hepatocellular Carcinoma Conferences, and G.I./Radiology/Surgery combined Conferences are held to discuss any interesting or difficult clinical cases and relevant clinical topics. For the monthly G.I. Grand Rounds, world-renowned experts in various G.I. diseases are invited to provide insight into the latest advances in treatment of G.I. diseases. Additionally, six to eight research experts are invited throughout the year to discuss the latest advances in G.I. Research. The UNM G.I. Fellowship Program is a dynamic program always looking for ways to improve the training process. The stated goal of the Gastroenterology and Hepatology Division is to have the best G.I. Fellowship training program in the country.

RESEARCH AND SCHOLARLY ACTIVITIES With the arrival of Dr. Thomas Ma as the Division Chief in January 2002, there has been a major expansion of basic and clinical research programs. Recent additions of Dr. Henry C. Lin (clinician and lab scientist with expertise in translational research in the fields of intestinal motility and transit) as the Chief of G.I. Section at the VAMC further strengthened the expanding G.I. research program. The total research funding in G.I. Division exceeds $26.6

97 million. As a comparison, the total research funding in 2000-2001 academic year was zero. Thus, the growth in research funding has been outstanding. There were over 33 publications from the Division during the academic year. Several faculty have international reputation in research and serve on key national research grant study sections. Dr. Ma served as a Chair of VA Merit Review Board and member of NIH study sections, Dr. Boedeker served as a member of NIH study section and Dr. Lin served on a NIH study section.

The research program and research opportunity for the G.I. fellows have also been greatly expanded during the past five years. All G.I. fellows have been provided with minimum of 6 months of protected time for research and given an opportunity to pursue both clinical and basic science research. There is also a dedicated academic track with 18 months of protected research time. With greater emphasis and opportunity for research involvement, all second and third year G.I. fellows have participated in important research projects and have presented abstracts at a national or regional scientific meeting.

CLINICAL OPERATIONS The clinical productivity of the G.I. Division remains at a very high level. All of the faculty continue to have clinical productivity at the top 10th percentile based on clinical RVUs.

Academic Year Total Clinical Billing Total Revenue Generated 2001-2002 $2,517,000 $640,000 2002-2003 $3,516,000 $996,000 2003-2004 $4,013,000 $1,139,000 2004-2005 $3,899,817 $975,817 2005-2006 $4,287,000 $1,048,704 2006-2007 $4,658,199 $1,379,937 2007-2008 $5,603,258 $1,659,557 2008-2009 $6,570,601 $1,941,960 2008-2009 $7,402,477 $2,031,516 2010-2011 $9,096,945 $2,326,420 2011-2012 $10,175,780 $2,694,146

Thus, the overall clinical productivity of the G.I. Division remains outstanding.

HONORS AND AWARDS  Stellar Consultant Award given to Joseph M. Alcorn, MD 2011  Stellar Consultant Award given to Michael W. Gavin, MD 2011  Stellar Consultant Award given to L. Trent Taylor, MD 2011

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

A major goal for the G.I. Division in the upcoming year is to expand on the improvements achieved during the last academic year in education, research, and clinical activities. A top priority of the Division is to continue expansion of G.I. endoscopic service. Recently, Center for Digestive Diseases was opened, which provides state-of-the-art clinical care in digestive diseases. It is anticipated a new 12,000 sq. ft. research facility dedicated to G.I. research (Center for Digestive Diseases Research) will open in August 2012. An important goal will be to recruit new faculty members with international reputation in research.

An important goal for the Division is to continue to increase funding in both clinical and basic research in the new academic year.

During the last six years, a major initiative in the complete re-hauling of the education program was undertaken. The new changes have made a huge impact in the fellowship training program. Full implementation of education activities will continue to occur in the 2012-2013 academic years and beyond.

APPOINTMENTS

FACULTY Name Title Effective date Michael D. Gilles, MD Assistant Professor of Medicine 7/1/2011 Prashant Nighot, PhD Research Assistant Professor 1/1/2012

STAFF Name Title Effective date Lisa K. Ereifej Professional Intern/Technical 8/1/2011 Kelly Fitzpatrick-Cuoco Research Technician 3 4/1/2012 Jesus Lopez Research Technician 1 8/1/2011

SEPARATIONS

FACULTY Name Title Effective date Michael D. Gilles, MD Assistant Professor of Medicine 6/30/2012 Eric E. Stone, MD Assistant Professor of Medicine 5/24/2012 Monica Delgado-Vargas, PhD Research Assistant Professor 5/18/2012 Dongmei Ye, PhD Research Assistant Professor 02/17/2012

STAFF Name Title Effective date Lisa K. Ereifej Professional Intern/Technical 4/6/2012 Linda Gutierrez Administrative Assistant 3 4/20/2012 Sibtain Ahmed, PhD Post-Doctoral Fellow 9/28/2011

PUBLICATIONS OF THE DIVISION AND FACULTY

Rana Al-Sadi, Ph.D. 1. Ye D, Guo S, Al-Sadi R, Ma TY. MicroRNA regulation of intestinal epithelial tight junction permeability. Gastro 141(4):1323-33, 2011.

Sanjeev Arora, M.D. 1. Arora S, Kalishman S, Dion D, Thornton K, Murata G, Fassler C, et al. Knowledge networks for treating complex diseases in remote, rural, and underserved communities. In: McKee A, Eraut M eds. Learning Trajectories, Innovation and Identity for Professional Development: Innovation and Change in Professional Education Volume 7. Springer Science and Business Media. 2011. 2. Deming P, Arora S. Tarbavirin in the treatment of hepatitis C. Expert Opin Investig Drugs, 20(10):1435-43, 2011. 3. Harkins MS, Raissy H, Moseley K, Luttecke K, Arora S. Extension for community healthcare outcomes project – asthma specialty consultation via telehealth to improve asthma care in rural New Mexico. US Respirat Diseases 7(1):7-9, 2011. 4. Thompson AJ, Patel K, Chuang WL, Lawitz EJ, Rodriquez-Torres M, Rustgi VK, Flisiak R, Pianko S, Diago M, Arora S, et al. Viral clearance is associated with improved insulin resistance in genotype 1 chronic hepatitis C but not genotype 2/3. Gut 61(1):128-34, 2012. 5. Ramzan M, Yadav SP, Gupta D, Arora S, Sachdeva A. Pediatric intensive care unit: an essential service to improve survival of childhood cancer in developing world. Indian J Pediatr, 2012. 6. Shah SK, Arora S, Skipper B, Kalishman S, Timm TC, Smith AY. Randomized evaluation of a web based interview process for urology resident selection. J Urol 187(4):1380-4, 2012. 7. Colleran K, Harding E, Kipp BJ, Zurawski A, Macmillan B, Jelinkova L, Kalishman S, Dion D, Arora S. Building capacity to reduce disparities in diabetes: training community health workers using an integrated distance learning model. Diabetes Educ 38(3):386-96, 2012.

Edgar C. Boedeker, M.D. 1. Frank DN, Robertson CE, Hamm CM, Kpadeh Z, Zhang T, Chen H, Zhu W, Sartor RB, Boedeker EC, Harpaz N, Pace NR, Li E. Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases. Inflam Bowel Dis 17:179-84, 2011. 2. Crane JK, Byrd W, Boedeker EC. Virulence inhibition by zinc in Shiga toxigenic Escherichia coli. Infest Immun 79:1696-705, 2011. 3. Lukyanenko V, Malyukova I, Hubbard A, Delannoy M, Boedeker EC, Zhu C, Cebotaru L, Kovbasnjuk. Entero-hemorrhagic Escherichia coli infection stimulates Shiga toxin 1 macropinocytosis and transcytosis across intestinal epithelial cells. Amer Journ Physiol Cell Physiol 301(5):C1140-9, 2011. 4. Li E, Hamm CM, Gulate AS, Sartor RB, Chen H, Wu X, Zhang T, Rohlf FJ, Zhu W, Gu C, Robertson CE, Pace NR, Boedeker EC et al. Inflammatory bowel diseases phenotype, C. difficile and NOD2 genotype are associated with shifts in human ileum associated microbial composition. PLoS One 7(6):e26284 2012.

I. Wyatt Byrd, Ph.D. 1. Crane JK, Byrd W, Boedeker EC. Virulence inhibition by zinc in Shiga toxigenic Escherichia coli. Infest Immun 79:1696-705, 2011.

Shuhong Guo, Ph.D. 1. Ye D, Guo S, Al-Sadi R, Ma TY. MicroRNA regulation of intestinal epithelial tight junction permeability. Gastro 141(4):1323-33, 2011.

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Henry C. Lin, M.D. 1. Collins BS, Lin HC. Double-blind, placebo-controlled antibiotic treatment study of small intestinal bacterial overgrowth in children with chronic abdominal pain. Jour Pediatr Gastro & Nutr 52(4):382-6 2011.

Thomas Y. Ma, M.D., Ph.D. 1. Subramanian VS, Subramanya SB, Rapp L, Marchant JS, Ma TY, Said HM. Differential expression of human riboflavin transporters -1, -2 & -3 in polarized epithelia: a key role for hRFT-2 in intestinal riboflavin uptake. Biochim Biophys Acta 1808:3016-21, 2011. 2. Ye D, Guo S, Al-Sadi R, Ma TY. MicroRNA regulation of intestinal epithelial tight junction permeability. Gastro 141(4):1323-33, 2011. 3. Ma TY, Anderson JM, Turner JR. Tight junctions and intestinal barrier. Johnson LR ed Textbook of Gastrointestinal Physiology. 5th Ed Elsevier Academic Press; Burlington, MA; 1043-88, 2012.

Denis M. McCarthy, M.D. 1. Littlefield AK, Verges A, McCarthy DM, Sher KJ. Interactions between self-reported alcohol outcome expectancies and cognitive functioning in the prediction of alcohol use and associated problems: a further examination. Psychol Addict Beha 25(3):542-6, 2011. 2. Hicks JA, Pedersen SL, Friedman RS, McCarthy DM. Expecting innovation: psychoactive drug primes and the generation of creative solutions. Exp Clin Psychopharmacol 19(4):314-20 2011. 3. Lanas A, McCarty DM, Voelker M, Brueckner A, Senn S, Baron JA. Short-term acetylsalicylic acid (aspirin) use for pain, fever, or colds – gastrointestinal adverse effects: a meta-analysis of randomized clinical trials. Drugs R D 11(3):277-88, 2011. 4. Treloar HR, McCarthy DM. Effects of mood and urgency on activation of general and specific alcohol expectancies. Addict Behav 37(1):115-8 2012. 5. McCarthy DM. Proton pump inhibitor use and Clostridium difficile colitis: cause or coincidence? J Clin Gastroenterol 46(5):350-3 2012. 6. McCarthy DM. Efficacy and gastrointestinal risk of aspirin used for the treatment of pain and cold. Best Pract Res Clin Castroenterol 26(2):101-12, 2012. 7. Burton CM, Pedersen SL, McCarthy DM. Impulsivity moderates the relationship between implicit associations about alcohol and alcohol use. Psychol Addict Behav, 2012. 8. McCarthy DM, Niculete ME, Treloar HR, Morris DH, Bartholow BD. Acute alcohol effects on impulsivity: associations with drinking and driving behavior. Addiction 10.1111, 2012.

Prashant Nighot, Ph.D. 1. Nighot PK, Blikslager AT. Chloride channel CIC-2 modulates tight junction barrier function via intracellular trafficking of occludin. Am J Physiol Cell Physiol 302(!):C178-87, 2012. 2. Meyerhoff RR, Nighot PK, Ali RA, Blikslager AT, Koci MD. Characterization of turkey inducible nitric oxide synthase and identification of its expression in the intestinal epithelium following astrovirus infection. Comp Immunol Microbiol Infect Dis 35(1):63-9, 2012. 3. Cuppoletti J, Blikslager AT, Shakrabarti J, Nighot PK, Malinowska DH. Contrasting effects of linaclotide and libiprostone on restitution of epithelial cell barrier properties and cellular homeostasis after exposure to cell stressors. BMC Pharmocal 12(1):3, 2012.

Gulshan Parasher, M.D. 1. Glass JP, Parasher G, Arias-Pulido H, Donohue R, Prossnitz ER, Cerilli LA. Mesothelin and GPR30 staining among a spectrum of pancreatic epithelial neoplasms. Int J Surg Pathol 19(5):588-96, 2011.

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Arun V. Pillai, M.D. 1. Csak T, Velayudam A (KNA Pillai A), Hritz I, Petrasek J et al. Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates non-alcoholic steatohepatitis and fibrosis in mice. Am J Physiol Gastrointest Liver Physiol 300(3):G433-41, 2011. 2. Dutt-Ballerstadt R, Evans C, Pillai AP, Orzeck E, Drabek R et al. A human pilot study of the fluorescence affinity sensor for continuous glucose monitoring in diabetes. J Diabetes Sci Technol 6(2):362-70, 2012.

Dongmei Ye, Ph.D. 1. Ye D, Guo S, Al-Sadi R, Ma TY. MicroRNA regulation of intestinal epithelial tight junction permeability. Gastro 141(4):1323-33, 2011.

OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

Joseph M. Alcorn, M.D. AD HOC REVIEWER OR EDITORIAL CONSULTANT  Veterans Administration Research Merit Review

JOURNAL/EDITORIAL REVIEWER  American Journal of Gastroenterology  American Journal of Physiology  Digestive Diseases and Sciences  Gastroenterology  Hepatology  Journal of Clinical Investigation  Journal of Hepatology  Laboratory Investigation

PROFESSIONAL AFFILIATIONS  American Association for the Study of Liver Diseases  American Gastroenterology Association

Sanjeev Arora, M.D. PROFESSIONAL AFFILIATIONS  American Association for the Advancement of Sciences  American Association for the Study of Liver Diseases  American College of Gastroenterology  American College of Physicians-American Society of Internal Medicine  American Gastroenterology Association  American Society of Gastrointestinal Endoscopy  Greater Albuquerque Medical Association  Practice Management Committee of American Society Gastrointestinal Endoscopy

Jehad Barakat, M.D. JOURNAL/EDITORIAL REVIEWER  Alimentary Pharmacology & Therapeutics Journal  American Journal of Gastroenterology  Digestive Diseases and Sciences  Journal of the American College of Surgeons

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PROFESSIONAL AFFILIATIONS  American Gastroenterology Association  American Society for Gastrointestinal Endoscopy

Edgar C. Boedeker, M.D. JOURNAL/EDITORIAL REVIEWER  American Association for the Study of Liver Disease  American College of Gastroenterology  American College of Physicians  American Federation for Clinical (Medical) Research  American Gastroenterological Association  American Society for Gastrointestinal Endoscopy  American Society for Microbiology  Gastroenterology Research Group  Infectious Diseases Society of America  North American Society for Pediatric Gastroenterology

GRANT REVIEWER  Canadian Foundation for Ileitis and Colitis, Grants Reviewer  Crohn’s and Colitis Foundation of America Reviewer’s Reserve  NIDDK/NIH Mucosal Pathobiology (MPB) Study Section, Permanent Member  NIH Botanicals Research Center, Ames, IA, External Advisory Board  NIH Reviewer’s Reserve

PROFESSIONAL AFFILIATIONS  Annals of Internal Medicine, Reviewer  Gastroenterology, Reviewer  Infection and Immunology, Reviewer  Journal Clinical Investigation, Reviewer  Journal Pediatric Gastroenterology and Nutrition, Reviewer  Reviews of Infectious Diseases, Reviewer

Michael W. Gavin, M.D. PROFESSIONAL AFFILIATIONS  American Gastroenterological Association  American Society for Gastrointestinal Endoscopy  Crohn’s & Colitis Foundation of America

Shuhong Guo, Ph.D. PROFESSIONAL AFFILIATIONS  American Gastroenterological Association  American Physiological Society  Society for Free Radical Biology and Medicine  Society for Neuroscience

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Martin G. Kistin, M.D. PROFESSIONAL AFFILIATIONS  American Association for Study of Liver Diseases  American College of Gastroenterology  American College of Physicians  American Gastroenterological Association  American Society of Gastrointestinal Endoscopy  Association of Specialty Professors

Kevin Kolendich, M.D. PROFESSIONAL AFFILIATIONS  Alpha Omega Alpha  American College of Gastroenterology  American Neurogastroenterology and Motility Society  American Society for Gastrointestinal Endoscopy

Henry C. Lin, M.D. JOURNAL/EDITORIAL REVIEWER  American Journal of Clinical Nutrition  American Journal of Gastroenterology  American Journal of Medicine  American Journal of Physiology: GI and Liver Physiology  American Journal of Physiology: Regulatory Physiology  Clinical Gastroenterology and Hepatology  Digestion  Digestive and Liver Diseases  Digestive Diseases and Sciences  Endocrinology  European Journal of Gastroenterology and Hepatology  Gastroenterology  Journal of Applied Physiology  Journal of Clinical Gastroenterology  Journal of Comparative Neurology  Journal of Endocrinology and Metabolism  Journal of Gastroenterology, Hepatology and Nutrition  Journal of Pediatric Gastroenterology and Nutrition  Journal of Physiology  Nature Clinical Practice: Gastroenterology and Hepatology  Neurogastroenterology and Motility  Peptides  Regulatory Peptides

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EDITORIAL BOARD  American Journal of Physiology: Gastrointestinal and Liver Physiology  Digestive Disease & Sciences, Motility Section Editor and Board Member  Digestive Disease & Sciences, Senior Associate Editor  GI Physiology, Contributing Reviewer

PROFESSIONAL AFFILIATIONS  American College of Physicians  American Gastroenterological Association  American Motility Society  American Physiological Society  International Group for the Study of Neurogastroenterology and Motility

Thomas Y. Ma, Ph.D., M.D. JOURNAL/EDITORIAL REVIEWER  American Journal of Clinical Nutrition  American Journal of Gastroenterology  American Journal of Pathology  American Journal of Physiology: Cell Physiology  American Journal of Physiology: Gastrointestinal Physiology  Canadian Journal of Gastroenterology  Digestion  Digestive Disease and Science  FASEB  Gastroenterology  Gut  Hepatology  Journal of Bioactive Polymers  Journal of Biological Chemistry  Journal of Cellular Physiology  Journal of Clinical Investigation  Journal of Laboratory and Clinical Medicine  Journal of Parenteral & Enteral Nutrition  Nutrition  Proceedings of Society of Experimental Medicine and Biology  Prostaglandins  The Scientific World Journal

EDITORIAL BOARD  World Journal of Gastrointestinal Pathophysiology

GRANT REVIEWER  Broad Medical Research Foundation  NIH Study Section: Special Emphasis Panel U34 Grants  NIH Study Section: Gastrointestinal Mucosal Pathobiology Section  VA Merit Review Study Section: Ad-hoc Member, Gastroenterology Section

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PROFESSIONAL AFFILIATIONS  American Association for the Advancement of Science  American College of Gastroenterology  American College of Physicians-American Society of Internal Medicine  American Gastroenterological Association  American Physiological Society  Association of Subspecialty Physicians  Crohn’s & Colitis Foundation of America  New York Academy of Sciences  Western Association of Physicians

Denis M. McCarthy, M.D. JOURNAL/EDITORIAL REVIEWER  Alimentary Pharmacology and Therapy  American Journal of Gastroenterology  Annals of Internal Medicine  Clinical Gastroenterology and Hepatology  Digestive Disease and Sciences  Gastrointestinal Endoscopy  GUT  Journal of the American Medical Association  New England Journal of Medicine  Pediatric Gastroenterology and Nutrition  Psychosomatic Medicine

EDITORIAL BOARD  Digestive Diseases and Sciences  Journal of Clinical Gastroenterology  Practical Gastroenterology, New York

PROFESSIONAL AFFILIATIONS  American Gastroenterological Association

Prashant Nighot, Ph.D. AD HOC REVIEWER OR EDITORIAL CONSULTANT  Avian Pathology

JOURNAL/EDITORIAL REVIEWER  World Journal of Gastroenterology

Gulshan Parasher, M.D. PROFESSIONAL AFFILIATIONS  American College of Gastroenterology  American College of Physicians  American Federation of Medical Research  American Gastroenterological Association  American Medical Association

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 American Pancreatology Association  American Society of Gastrointestinal Endoscopy  Pancreatic Cancer Action Network

Arun V. Pillai, M.D. PROFESSIONAL AFFILIATIONS  American College of Gastroenterology  American College of Physicians  American Gastroenterological Association  American Society for Gastrointestinal Endoscopy

Shazia Rafiq, M.D. PROFESSIONAL AFFILIATIONS  American College of Gastroenterology  American College of Physicians  American Society for Gastrointestinal Endoscopy  Pakistan Medical and Dental Council

Eric E. Stone, M.D. PROFESSIONAL AFFILIATIONS  American College of Physicians  American Gastroenterological Association  American Medical Association  American Society for Gastrointestinal Endoscopy

Robert Strickland, M.D. PROFESSIONAL AFFILIATIONS  Albuquerque and Bernalillo Medical Association  American Association for Study of Liver Diseases  American College of Physicians  American Federation for Medical Research Foundation  American Gastroenterological Association  American Society of Gastrointestinal Endoscopy  Australian Medical Association  Gastroenterological Society of Australia  New Mexico Medical Society  Royal Australasian College of Physicians  Royal Society of Medicine  Society for Experimental Biology and Medicine  Western Association of Physicians  Western Society of Clinical Investigation

Lance Taylor, M.D. PROFESSIONAL AFFILIATIONS  American Association for the Study of Liver Diseases  American Gastroenterological Association  American Society of Gastrointestinal Endoscopy

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OUTSIDE SPONSORED RESEARCH

Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total Probiotics Effect on UNM SOM Research Al-Sadi, Rana Intestinal Tight Junction Research 11/01/2010 10-31-2011 24,618 24,618 Allocation Committee Barrier Demonstration and Replication of the ECHO Arora, Robert Wood Johnson Model: A Robust 02/15/2009 02/14/2012 1,666,666 5,000,000 Sanjeev Foundation Paradigm to Expand Best Practice Care for Vulnerable Populations Project ECHO: Arora, New Mexico State Extension for State 07/01/2005 06/30/2012 528,571 3,700,000 Sanjeev Legislature Community Health Outcomes Project ECHO: Arora, New Mexico Extension for State 07/01/2007 06/30/2012 1,028,571 7,200,000 Sanjeev Department of Health Community Health Outcomes Project ECHO Hepatitis C Ambulatory Care Arora, Agency for Healthcare Quality Improvement in 09/30/2009 07/31/2012 368,323 1,104,970 Sanjeev Research and Quality New Mexico through Health Information Technology Agency for Healthcare Expansion of Rural Research and Quality, Arora, Health Care Research Minority Research Federal 09/21/2007 08/31/2012 500,000 1,500,000 Sanjeev Infrastructure through Infrastructure Support the ECHO Model Program Hepatitis C Treatment Arora, University of South Expansion Initiative: 09/01/2011 08/31/2012 116,224 116,224 Sanjeev Florida Evaluation and Technical Assistance Veterans Arora, IPA (10 IPA’s with Administration Medical Research IPA 03/01/2011 02/28/2013 488,383 976,767 Sanjeev Project ECHO) Center Retinal Imaging via Arora, Vision Quest Community Health 09/05/2011 09/04/2012 50,000 50,000 Sanjeev Biomedical LLC Workers

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Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total ARRA- Shiga-Toxin: Boedeker, Johns Hopkins Uptake Mechanisms Research 2000792087 09/01/2010 08/31/2011 27,160 54,320 Edgar C. University and Intracellular Actions Veterans Boedeker, Administration IPA: Isaac Wyatt Byrd Research IPA/W. Byrd 04/05/2010 08/31/2011 133,095 133,095 Edgar C. Medical Center Boedeker, VA/DOD Merit Attaching/Effacing E.coli Research 10/01/2009 09/30/2011 135,000 270,000 Edgar C. Review Award as Vaccine Vectors Effect of Zinc in Boedeker, State University of Attaching and Effacing Research R677721 06/01/2010 05/31/2013 110,000 330,000 Edgar C. New York at Buffalo E.coli Infection Veterans Lin, Henry IPA: Ramadass IPA/Ramadass Administration Research 08/01/2009 07/31/2011 107,811 107,811 Chia-nan Balamurugan Balamurugan Medical Center Bacterial Overgrowth Lin, Henry VA Merit Review Associated with Chronic Research VAMC 20939/Lin 07/01/2008 06/30/2012 50,000 450,000 Chia-nan Award Multi-Symptom Illness Complex Department of Defense Small Intestinal Lin, Henry Congressionally Bacterial Community in Research 07/01/2010 06/30/2013 211,380 634,142 Chia-nan Directed Medical Gulf War Illness Research Programs NIH/National ARRA Autophagy and Ma, Thomas Y. Research 5RC1AI086845-02 09/01/2009 08/31/2012 338,000 1,000,000 Institutes of Health Crohn's Disease Regulation of Intestinal Ma, Thomas Y. VA Merit Review Paracellular Research 07/01/2004 06/30/2012 150,000 782,000 Permeability TNF-alpha Regulation of NIH/National Ma, Thomas Y. Intestinal Paracellular Research R01DK064165-07 09/01/2009 08/31/2014 235,000 1,675,000 Institutes of Health Transport NIH/National Institute Interleukin-1 Beta of Diabetes and Ma, Thomas Y. Modulation of Intestinal Research R01DK081429-03 06/01/2009 05/31/2014 230,000 1,500,000 Digestive and Kidney Tight Junction Barrier Diseases

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GENERAL INTERNAL MEDICINE

ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Arti Prasad, M.D. Professor of Medicine Interim Chief, Division of General Internal Medicine (UNM)

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

EDUCATION  GIM exceeded the GIM’s quota of educational hours by almost 100 hours.  Health Equity curriculum: As Bernalillo County’s public medical center, we care for many disadvantaged patients. As for the HSC, we in GIM take our mission to care for disenfranchised populations very seriously. We currently lead the country in how we train medical students to understand the impact of social determinants on ill health, i.e., income, education, environmental conditions as well as ethnicity. This is an active area of educational development in GIM, developed, implemented and directed by Dr Cynthia Arndell, and our goal is to train doctors with an enhanced sense of compassion and social justice.  Continuation of Health Equity: Introduction to Principles of Public Health Course. This 2 week 40 course is required for all matriculating Phase I students which introduces students to the impact of social determinants on health using community as classroom.  Continuation of Phase I Homeless Panel Discussion/ (1 session) and Interviews with Homeless through community agencies serving homeless populations followed by reflection and debrief in Foundations of Clinical Practice.  Continuation of the inter-professional Post Discharge Home Visit Experience required of all 3rd year medical students in the IM Clerkship. Focus is on effective discharge planning through interprofessional collaboration, health literacy and cultural diversity.  Continuation of Street Medicine Elective – collaborative undertaking between HSC (CON, COP, SOM) and community homeless health clinics/respite shelters and street outreach teams (e.g HCH, Barrett House) to give senior students “hands on” experience in street medicine and shelter care.  Revising existing 4th year Ambulatory Care Rotation requirement for all Phase III students to better reflect principles of social justice and advocacy. This has been an extremely ambitious effort and is solidly collaborative among multiple disciplines within and outside of HSC including ALBQ police dept. and UNM law school. New piloted seminars include Public Health Law, Communication in the Trenches, Social Determinants of Health and Global Health.  Invited presentations at national and international conferences. Sept 2011 Grand Round series, "Social Determinants of Health"  Addiction: Dr Simson is a professor and consultant for the Southwest Institute for the Advancement of Psychotherapy (SIAP). SIAP created a Masters of Psychopharmacology which is credentialed through the New Mexico State University in Las Cruces. Dr Simson created an addiction curriculum specifically for the clinical psychologists who are working towards prescriptive authority and he delivered a weekend of lectures to these students in August. Dr. Simson also is a physician volunteer on the New Mexico Medical Cannabis Advisory Board which holds public hearings twice a year. Dr. Simson taught 16 hour block on Addiction Medicine August 18-19 at NMSU, Las Cruces in the Masters of Psychopharmacology Curriculum.

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 Integrative Medicine in Residency Track: This past year, GIM/SIM strengthened the Integrative Medicine Track in our IM Residency Program, the first of its kind in this country. The project is led by Dr. Prasad. The track currently enrolls 6 residents. The Primary Care Residency track started last year also continues to grow.  CME – Success of the Advances in Primary Care.

DIVERSITY  Edward Fancovic M.D. was appointed as Director for LGBT Equity and Inclusion within the UNMHSC Office of Diversity in September 2011, and his FTE in this role has been expanded beginning July 2012. The AAMC has included LGBT (lesbian, gay, bisexual, transgendered) status in its diversity goals for US medical schools, and UNMHSC has been in the forefront by designating a dedicated faculty member to focus on these issues. Dr. Fancovic's role will include assessment of current workplace and educational climate for LGBT faculty, residents, students and employees; development of internal support mechanisms for this community within the HSC; outreach and networking to the larger LGBT community within UNM and Albuquerque; and examination/development of LGBT-related curriculum for the education of health care providers.

RESEARCH AND SCHOLARLY ACTIVITIES Clinical Trials 1. HRRC 10-537: Aleglitazar is closed to enrollment (2 pts) 2. HRRC 11-629 Ranolazine in drug naive diabetics (1 patient on study, still enrolling) 3. HRRC 12-358 Ranolazine in diabetic subjects on metformin but with HgbA1c between 7-10; Site visit is complete, HRRC just approved study, were are waiting to enroll patients 4. Takada 875-306 CV study in diabetes; site selection done and we have been approved. We are submitting forms to HRRC now. We need to get HRRC approval before we can enter patients 5. Novartis CACZ885M2301: We have had the site selection and are waiting to hear if we were selected. This is a study in patients with current and recent past ACS. 6. BBHI: Drs. Rosenberg and Shah: This is a CTSC grant to study 10 patients with diabetes combining the MRI and MMP studies from Dr. Rosenberg's lab with the epigenetics and proteomics data from Dr. Shah's lab. We have selected the 10 subjects and this pilot study, if it is able to show markers in diabetics with elevated hsCRP levels for vascular changes seen in vascular cognitive impairment, will be used to submit for and RO-1 Grant from the NIH.

Education Grants 1. Decade of Design in collaboration with UNM School of Architecture- awarded 6-12; purpose: to develop inter-professional educational experiences among students from HSC, business, architecture and law related to designing urban neighborhoods for health equity 2. SEAC –awarded 9-11- purpose: to integrate GIS mapping into Health Equity: Introduction to PH course 3. Weil Foundation – received another 30K in award for the continuation of the IMR track. 4. HRSA-applied in collaboration with MPH program 4-12- purpose: to create a longitudinal interprofessional community assessment project for medical and MPH students-pending 5. HRSA – applied in collaboration with the Preventive Medicine program to integrate Integrative Medicine education into the existing PMR curriculum – submitted July 2012 – pending.

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Other grants 1. Participated as a consultant on the CTSC funded research project on meditation in post-herpetic neuralgia – resulted in two poster presentations at national and international meetings 2. Submitted two proposals – One to ACS with Marianne Berwick and Jennifer Hay - "Using genomics to address disparities in Hispanics' skin cancer awareness" , and the second to NIH Pain Consortium via Altarum Institute/Palladian Partners in collaboration with CON for a P20 Center Grant, with a focus on pain management. 3. “Integrative Medicine in Residence (IMR): An Innovative Special Interest Track at the University of New Mexico”, Arti Prasad, MD, Robert Leverence, MD, poster presented at the Society of General Internal Medicine Annual Meeting, May 4-7, 2011, Phoenix, AZ

CLINICAL OPERATIONS  GIM productivity - 6% higher than the last year (95.41% as compared to 87%).  Successful recruitment efforts for the NEH mid-level position, west side IM physician #1, two faculty recruitment for the new SWM Clinic

Primary Care and PCMH (Patient Centered Medical Home)  Working in a public medical center has its challenges but also opportunities. Caring for people of diverse backgrounds and at times desperate circumstances keeps us grounded in the need to not only treat all individuals compassionately but also safely and efficiently. It is now recognized that new systems of care utilizing new technologies, new administrative structures for decision-making and new team-based approaches have tremendous potential to revolutionize how we care for people. Barbara Flores who was one of the major directors of the entire PCMH program has retired.  We have a new Outpatient Consent Form that is much improved and easily understood by patients. It is written in English, Spanish and Vietnamese. It is available on line in Power Forms.  Patient Portal goes live by the end of September. Patients will have the ability to access their clinical notes, labs and some procedures. Patient messaging to the provider will NOT be turned on initially but will be soon. We will need to establish "pools" within each clinic to help manage the incoming messages, to triage and disseminate the messages to the appropriate party. LoboCare and NEH will be the pilot sites.  “Pools": we will have three sets of "pools" in each primary care office: RX refills, Closing the referral gap, and the Patient Portal messaging. There was a week-long LEAN session to help define what the pools responsibility will be and how to establish the pools in each office. This has been beta tested at LoboCare and 1209 and it seems to work. The pool for closing the referrals at 1209 takes a lot of on hands time, about 0.6 FTE. It is not an automated process. Beth Fingado's group is developing a "dashboard" for the PCMH that looks incredibly good showing improvement in our clinic targets ( etc., HgbA1c) and decreasing hospitalizations and ER visits. This will be available soon.  NCQA recognition was obtained last year and we have Level 1 recognition. We are preparing ourselves for the level 2 recognition.  Center for Excellence for Rheumatological Care at the West Side: Two years ago Dr. Madhu Arora recognized that patients at the UNM West Side clinic had long waits of greater than 6 months for Rheumatology consultation. She took the initiative to gain expertise in Rheumatology and now participates weekly in the Rheumatology ECHO program, wherein she presents and co-manages complicated rheumatological cases with the division chief of Rheumatology. In doing so she makes rheumatological care available to patients who live on the West Side of Albuquerque and Rio Rancho. After 2 years of attending the Rheumatology ECHO clinics and taking the Advanced Rheumatology Course Examination offered by the American College of Rheumatology in January of 2012, the UNM West Side Clinic was designated as a center for excellence for Rheumatological care and Dr. Arora got

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the additional designation by the American College of Rheumatology of being a Junior Rheumatologist. This designation has permanently expanded care for this specialty in the West Side.  Pharmacist-Clinicians in the PCMH: Implementing a pharmacist clinician directed refill clinic in Primary Care: GIM developed a process for pharmacist clinicians to facilitate prescription refills of chronic medications. This process was intended to increase the efficiency of the refill process and decrease medical provider workload in processing refill requests. The refill clinic was also designed to decrease the turnaround time from the initial request from the patient or pharmacy to patient being able to obtain their medication refill at the pharmacy. Pharmacist clinicians in New Mexico are in a unique position to assist with refilling chronic medications given their ability to prescribe under protocol.  New Community based SWM Clinic: GIM was able to develop a business plan for the move of the GMC to the community. GIM was also able to receive additional UCP funds to hire a couple of new faculty for the same clinic. As of July 2012, the GMC moved and two additional faculty members were hired. Dr. Jenny Jernigan moved her practice from 1209 clinic to SWM to assume the Medical Director’s position.  AAMC Faculty Forward results FOR 2011 show GIM faculty having 100% satisfaction in DOIM and in their jobs as compared to other clinical divisions and departments.

HONORS AND AWARDS  Dana Fotieo, M.D. Invited ACP Fellowship Effective 9/1/2012  Arti Prasad, MD. Vision 2020 NM Delegate, Equality in Sight, Drexel University  George Comerci, MD. Selected to develop a Non-Interventional Pain curriculum for AAPM  Cynthia Arndell, M.D. Nominated for ACP Fellow -9-12  Julie Broyles, M.D. – Phase II Teaching Recognition

ADMINISTRATION

Robert Fritch, M.D. CMO UNM Medical Group George Comerci, M.D. Medical Director – Pain Clinic Jennifer Benson, M.D. Assistant Professor, Block Co-Chair FCP Bronwyn Wilson, M.D. Associate Dean, Academic Affairs Cynthia Arndell, M.D. Co-Director Inter Professional Education Edward, Fancovic, MD Director of LGBT Equity and Inclusion Ann Gateley, MD, Medical Director for USA Track & Field Indoor Championships Jennifer Jernigan, MD Medical Director of SW Mesa Clinic

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INTEGRATIVE MEDICINE

It has been a busy and productive year for SIM and Center for Life as we’ve pursued the multiple aspects of our mission. CFL was selected as one of the CFL selected as 1/29 top integrative medicine centers in the country. The other highlights are:

EDUCATION Professional education  Increased the number of 4th-year medical students from four (4) during FY11 to five (5) during FY12  Increased the number of graduate medical residents from seven (7) during FY11 to eight (8) during FY12  No licensed Doctors of Oriental Medicine participated in the observational internship, which is a decrease from two (2) in FY11.  Increased the number of Licensed Massage Therapists participating in the observational internship from one (1) during FY11 to two (2) during FY12.

Patient education  107 people participated in L&L Lectures; total of 9 hours  85 people participated in CFL Workshops in FY12; total of 45.50 workshop hours and an average workshop satisfaction rating of 4.91  242 people participated in CFL classes in FY12; total of 79 class hours  187 people participated in the Mindfulness courses in FY12; total of 152 course hours

RESEARCH AND SCHOLARLY ACTIVITIES  The Section of Integrative Medicine has been awarded for FY13 a $25,000 grant from the Weil Foundation, Creating a Holistic Internist for the 21st Century: Integrative Medicine in Residency at UNMHSC.

CLINICAL OPERATIONS  The Center for Life’s total number of patient visits during FY12 was 10,016, approximately the same as FY11.  Center for Life generated $2,214,155 in clinical charges during FY12 a 16% increase from FY11.  A full time physician position was in the FY12 budget; multiple interviews were conducted; and the position offered to one of the candidates. Unfortunately, salary has been an issue and the position remains vacant.

COMMUNITY ACTIVITIES  Community Service: Center for Life participated in ninety-one (91) community outreach events (227 hours) in FY12 and reached 3,204 individuals.

Integrative Medicine: Significant plans and recommendations for the near future

The Center for Life is in the early stages of developing an integrative primary care clinic, which will include:  Physician – 2.0 FTE clinical time  Doctor of Oriental Medicine – 1.0 FTE clinical time  Doctor of Chiropractic Medicine – 1.0 FTE clinical time  Licensed Massage Therapist – 1.0 FTE clinical time

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SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

EDUCATION  Primary Care Curriculum: GIM Faculty will continue their very active role in medical education. We are begun an Ambulatory Care component in our IM Clerkship. Currently there are only VA sub-specialties that are participating in it and no UNM primary care. We had 16 students in the first block. We will journey through our third year of the new Integrative Medicine and Primary Care Residency tracks and perhaps be able to include integrative medicine education into the PMR.  Health Equity SOM curriculum Continue implementing and revising above initiatives. Develop and pilot 4th year electives related to comprehensive care of underserved populations; includes Undocumented Immigrants, Prison Health and High Risk Women and Adolescent Health rotations. Under the guidance of PEAR office, continue to develop robust evaluation tools Continue to disseminate scholarly work through national and international presentation and publishing

RESEARCH AND SCHOLARLY ACTIVITIES  NIH 8-2012 study with Cheryl Aine (Mind Institute) on cognitive changes associated with statin use. The grant has been submitted and we are waiting to hear whether it is accepted and funded.  GRADE Study with Dr. Dave Schade. We just received information on 9/14/12 that the grant has been approved and funded but the funding has been decreased from what was budgeted. We are waiting to see how this will affect our part of the study.  Potential studies: Pfizer Phase IIb study of PCSK9 in patients with hyperlipidemia. We are waiting to hear if we have been selected for this trial.  QI projects: We propose to develop a dashboard of uniform quality projects at each clinic under the leadership of the medical directors. This will be coordinated with the UH and the DOIM’s IMQG.

CLINICAL OPERATIONS  We propose to develop new models of clinical care at the SWM clinic  Involve all residents in Quality projects  Develop a performance plan for the medical directors based on productivity, efficiency, quality and patient satisfaction  Continue to improve efficiency of the EMR by working with the HIM  Meet the Departmental benchmark in Clinical work RVU’s

COMMUNITY ACTIVITIES We plan to continue with our current community engagement but GIM’s vision is to involve more faculty members in various community outreach activities.

ADMINISTRATION  Electronic Medical Records and Health Information System: Dr. Philip Kroth serves as the Associate CMIO, University Hospitals. The PCMH/EMR committee will be developing a number of evidence-based guidelines that will be either on the M-pages or on a separate page to be created by IT and Phil Kroth as a "reference page" with links to medical management/guidelines for chronic diseases.

HONORS AND AWARDS Recognition of Faculty and Staff for significant achievements on both a local and national level

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APPOINTMENTS

FACULTY

Robert Fritch, M.D. CMO UNM Medical Group 7/1/2011 George Comerci, M.D. Medical Director – Pain Clinic 7/1/2011 Jennifer Benson, M.D. Assistant Professor, Block Co-Chair FCP 7/8/2011 Bronwyn Wilson, M.D. Associate Dean, Academic Affairs 9/1/2011 Cynthia Arndell, M.D. Co-Director Inter Professional Education 2/1/2012 Edward, Fancovic, MD Director of LGBT Equity and Inclusion 8/1/2011 Ann Gateley, MD, Medical Director for USA Track & Field Indoor 2012 Championships Jennifer Jernigan, MD Medical Director of SW Mesa Clinic 7/1/2012

STAFF

Mimi Kessinger PAC 11/10/2011 Tammi Berry Administrative Asst. II 9/10/2011 Whitney Schluter CNP 3/15/2012 Diane Noya M.D. 3/27/2012

SEPARATIONS

FACULTY

Robert Leverence, M.D. Professor 7/6/2011 Ellen Cosgrove, M.D. Professor 10/1/2011

STAFF

Jennifer Trujillo Administrative Asst. II 11/21/2011

PUBLICATIONS OF THE DIVISION AND FACULTY

William Abeyta, M.D. N/A

Allen Adolphe, M.D., Ph.D. 1. Adolphe, A.B., Huang, X, and Cook, L. Carotid Intima-media Thickness Determined Vascular Age and the Framingham Risk Score. Crit. Pathways in Cardiol. [in press, December 2011]

Mara Archambault, M.D. N/A

Cynthia Arndell, M.D. N/A

Madhu Arora, M.D. N/A

Jennifer Benson, M.D. N/A

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Jessica Bigney, M.D. N/A

Julie Broyles, M.D. N/A

Amandeep Chadha, M.D. N/A

George Comerci, M.D. N/A

Kevin Edwards, M.D. N/A

Edward Fancovic, M.D. N/A

Dana Fotieo, M.D. 1. Pierce JR, Chang B, Rogers KM, Jernigan JR, Fotieo D, Kang H, Leverence RR, “Redesign of an Internal Medicine Rotation for Compliance with ACGME Duty-Hour Restrictions: Operational Challenges, Education Efforts and Professional Satisfaction.” Journal of Graduate Medical Education; Volume 4, issue 1: 97-100; March 2012.

Gregory Fotieo, M.D. N/A

Robert Fritch, D.O. N/A

Ann Gateley, M.D. N/A

David V. Gonzales, M.D. N/A

Frederick Hashimoto, M.D. N/A

Cynthia Heins, M.D. N/A

Jennifer Jernigan, M.D. 1. Pierce JR, Chang B, Rogers KM, Jernigan JR, Fotieo DR, Kang H, Leverence RR, “Redesign of an Internal Medicine Rotation for Compliance with ACGME Duty-Hour Restrictions: Operational Challenges, Education Efforts and Professional Satisfaction.” Journal of Graduate Medical Education; Volume 4, issue 1: 97-100; March 2012. Margaret Lieberman, M.D. N/A

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Melissa Martinez, M.D. N/A

Ann Morrison, M.D. N/A

Glen Murata, M.D. N/A

Arti Prasad, M.D. N/A

J. Mitchell Simson, M.D. N/A

Carolyn Voss, M.D. N/A

Bronwyn Wilson, M.D., MPH N/A

Ellen Yee, M.D., MPH N/A

OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

William Abeyta, M.D. N/A

Allen Adolphe, M.D., Ph.D. N/A

Mara Archambault, M.D. N/A

Cynthia Arndell, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  Arndell C, “Development of a Community-Engaged interprofessional Course on Health Equity”. (Presentation). Network Towards Unity for Health International Conference, Thunder Bay, Canada, October 2012.  Arndell C, “Use of AFMC Primer in the Health Equity: Introduction to Public Health”. (Presentation). American Association of Colleges. Washington, D. C., September 2012.  Arndell C, Eldredge J, Steimel L, “The Public Health Certificate at the University of New Mexico School of Medicine”. (Workshop). New Mexico American Public Health Association. Albuquerque, New Mexico. April 2012.  Arndell C, “Faculty Development for Teaching Public Health to Medical Students”. (Panelist). American Association of Medical Colleges and Association for Prevention Teaching and Research.Washington, D.C. April 2012.

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 Arndell C. “Health Equity: Introduction to Public Health; A Model for Interprofessional Education”. (Presentation). Josiah Macy Jr. Foundation Conference on Interprofessional Education. Alexandria, Virginia. April 2012.  Arndell C. “Creating Interprofessional Curricula Using Fink’s Model of Curriculum Development”. (Paper Presentation). Collaborating Across Borders III Conference. Tuscon, Arizona. November 2011.  Arndell C. “Social Determinants of Health: It’s Place in Redefining Medicine”. (Panelist). Association of American Medical Colleges Annual Meeting. Denver, Colorado. November 2011.

COMMUNITY OUTREACH  Board Member- Good Shepherd Agency for Homeless Men and Rehabilitation Program  Board Member- Saranam Program for Homeless Families  NM Youth Alliance member  Faculty Advisor and volunteer for medical student homeless outreach clinics

PROFESSIONAL AFFILIATIONS  HSC Executive Deans Committee member  SOM Curriculum Committee member  UNM Faculty Senate Committee member

Madhu Arora, M.D. N/A

Jennifer Benson, M.D. N/A

Julie Broyles, M.D. N/A

Amandeep Chadha, M.D. N/A

George Comerci, M.D. JOURNAL/EDITORIAL REVIEWER  The Language of Pain: Finding Words, Compassion and Relief-Reviewed by George D. Comerci, MD, FACP, The Pharos/Autumn 2011, Pg. 48-49.

Kevin Edwards, M.D. N/A

Edward Fancovic, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  HIV in New Mexico presentation to NMPower (an ABQ-based group of gay/bisexual men age 18-29)  Alibi interview on LGBT health: http://alibi.com/news/41824/Were-Both-Dad.html

Dana Fotieo, M.D. COMMUNITY OUTREACH  Double Eagle Elementary PTA, 5/09- 5/11, President  Hospitality Committee Desert Ridge Middle School, 8/11-present, co-chair

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Gregory Fotieo, M.D. N/A

Robert Fritch, D.O. PROFESSIONAL AFFILIATIONS  Volunteer Medical Consultation for uninsured Albuquerque Asian population.  Circuit rider for Practical Immersion Experience Medical Students. Served as the faculty evaluator for two students in northern NM.  Narrative Strand Mentor. Served as the faculty mentor for a second year medical student in this regard the past summer.  Volunteer at East Central Ministries and Albuquerque Opportunity Center

Ann Gateley, M.D. N/A

David V. Gonzales, M.D. N/A

Frederick Hashimoto, M.D. N/A

Cynthia Heins, M.D. N/A

Jennifer Jernigan, M.D. PROFESSIONAL AFFILIATIONS  American College of Physicians  Society of General Internal Medicine  Association of Program Directors in Internal Medicine

Margaret Lieberman, M.D. N/A

Melissa Martinez, M.D. EDITORIAL BOARD  Editor for the Newsletter of the New Mexico Chapter of the American Academy of Family Physicians, Delegate to the American Academy of Family Physicians Congress of Delegates

PROFESSIONAL AFFILIATIONS  Co-Chair of the Immunizations committee which is part of the Clinical Improvement Intuitive of the Department of Health and the New Mexico Medical Society

Ann Morrison, M.D. PROFESSIONAL AFFILIATIONS  American College of Physicians – American Society of Internal Medicine  Society of General Internal Medicine  American Academy on Communication in Healthcare

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Glen Murata, M.D. N/A

Arti Prasad, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  “Integrative Medicine in Residence (IMR): An Innovative Special Interest Track at the University of New Mexico”, Arti Prasad, MD, Robert Leverence, MD, poster presented at the Society of General Internal Medicine Annual Meeting, May 4-7, 2011, Phoenix, AZ  “Comparison of Usual Care Alone with Usual Care Plus Meditation in Adults with Post-Herpetic Neuraligia (PHN), Robin Meize-Grochowski, Arti Prasad, Ron Schrader, Christine Murray-Krezan, Michelle DuVal, Bruce W. Smith, Carla J. Herman, presented at the Council for the Advancement of Nursing (CANS) conference in Washington, D.C., October 19th, 2011  “Meditation in Older Adults with Postherpetic Neuralgia (PHN); Robin Meize-Grochowski, RN, PhD, Arti Prasad, MD, Ron Schrader, PhD, Michelle DuVal, MA, Bruce W. Smith, PhD, Carla J. Herman, MD, MPH; will be presented at the 2012 International Research Congress in Integrative Medicine & Health in Portland, OR, May 15-18, 2012

COMMUNITY OUTREACH  Board Member – Medical Advisory Board of the Cancer Services of NM

PROFESSIONAL AFFILIATIONS  American College of Physicians  Society of General Internal Medicine  ACLGIM  Society of Integrative Oncology  American Association of Physicians of India (AAPI)  Consortium of Academic Health Centers for Integrative Medicine  Vision 2020, Equality in Sight

J. Mitchell Simson, M.D. N/A

Carolyn Voss, M.D. N/A

Bronwyn Wilson, M.D., MPH N/A

Ellen Yee, M.D., MPH N/A

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OUTSIDE SPONSORED RESEARCH

Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total Phoenix Area Cosgrove, 11th Annual Advances in Indian Health Education LMS401142053 4/1/2011 9/30/2011 0 150 150 Ellen M. Indian Health Conference Service Cosgrove, Gallup Indian 11th Annual Advances in Education LMS5411D0218 4/1/2011 9/30/2011 0 50 50 Ellen M. Medical Center Indian Health Conference Cosgrove, Whiteriver IHS 11th Annual Advances in Education LMS401112177 4/1/2011 9/30/2011 0 90 90 Ellen M. Hospital Indian Health Conference Cosgrove, 11th Annual Advances in Pueblo of Sandia Education S110489 4/1/2011 9/30/2011 0 50 50 Ellen M. Indian Health Conference Cosgrove, Crownpoint 11th Annual Advances in Education LMS5411B0125 4/1/2011 9/30/2011 0 60 60 Ellen M. Healthcare Facility Indian Health Conference Chinle Cosgrove, Comprehensive 11th Annual Advances in Education LMS5411A0292 4/1/2011 9/30/2011 0 60 60 Ellen M. Health Care Indian Health Conference Facility Cosgrove, Northern Navajo 11th Annual Advances in Education LMS511F0105 4/1/2011 9/30/2011 0 50 50 Ellen M. Medical Center Indian Health Conference Cosgrove, Whiteriver IHS 11th Annual Advances in Education 311394 4/1/2011 9/30/2011 0 90 90 Ellen M. Hospital Indian Health Conference Cosgrove, Gallup Indian 11th Annual Advances in Education LMS5411D0257 4/1/2011 9/30/2011 0 90 90 Ellen M. Medical Center Indian Health Conference Cosgrove, State of New 11th Annual Advances in Education 66500-0000076286 4/1/2011 9/30/2011 0 140 140 Ellen M. Mexico Indian Health Conference Cosgrove, Jicarilla Apache 11th Annual Advances in Education 130608 4/1/2011 9/30/2011 0 90 90 Ellen M. Nation Indian Health Conference Cosgrove, Shoshone- 11th Annual Advances in Education 2036 4/1/2011 9/30/2011 0 180 180 Ellen M. Bannock Tribe Indian Health Conference Cosgrove, Northern Navajo 11th Annual Advances in Education LMS5411F0118 4/1/2011 9/30/2011 0 110 110 Ellen M. Medical Center indian Health Conference Improving the Diagnosis and Cosgrove, Sanofi-Aventis Treatment of Children with Education 33635 9/2/2010 9/1/2011 0 272,150 272,150 Ellen M. Allergic Rhinitis (PPVNE06946 Adolphe, Hoffman LaRoche Clinical Trial Phase III Clinical 100001144 7/1/2008 5/13/2012 $77,010 $231,030 $308,040 Allen B Adolphe, PPD Development Clinical Trial Phase II Clinical 100001367 12/14/2007 12/13/2012 24,956 74,856 99,825 Allen B

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Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total

Adolphe, Nova NorDisk Clinical Trial Phase III Clinical 100033744 2/24/2010 2/23/2015 18,551 55,655 74,206 Allen B

Adolphe, Hoffman La Roche Clinical Trial Phase III Clinical 100001144 10/29/2010 10/22/2013 34,375 103,125 137,500 Allen B Adolphe, Gilead Sciences Clinical Trial Phase III Clinical 100016462 1/10/2012 1/9/2017 14,731 44,194 58,925 Allen B Adolphe, Gilead Sciences Clinical Trial Phase III Clinical 100016462 6/15/2012 6/14/2017 12,510 50,000 62,510 Allen B Voss, DHHS-Indian Locum Tenens IHS Radiology HHS1242200910071I Carolyn Clinical 10/1/2010 9/30/2011 0 50,000 50,000 Health Service Agreement, Option Year 2 Mod 4 M. Prasad, Weil Foundation Creating a Holistic Internist for Education 101264477 7/1/2011 6/30/2012 0 54,507 54,507 Arti Grant the 21st Century

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GERIATRICS AND PALLIATIVE MEDICINE ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Carla J. Herman, MD, MPH Professor of Medicine Chief, Division of Geriatrics and Palliative Medicine

EDUCATION Dr. Lisa Marr is appointed as the Fellowship Director for our newly accredited ACGCME Palliative Medicine Fellowship. Our first fellow began July 2012.

Dr. Lisa Marr was a keynote speaker at the March 2012 Whole Person Care National Symposium in Sydney Australia.

Dr. Judith Kitzes continues as Director of Special Projects including Medical Educators Scholars Program (MES), the SEAC medical education research program, and Academic Support in undergraduate medical education.

Dr. Carla Herman has continued her funding through UC Irvine to improve teaching of Motivational Interviewing with geriatric patients and caregivers. She continues as PI for the Donald W. Reynolds Next Steps grant on improving interprofessional geriatric education.

Drs. Devon Neale and Lisa Marr direct bimonthly Palliative Care ECHO Clinics.

Dr. Janice Knoefel directs the bimonthly Dementia Care ECHO Clinic in collaboration with the NM Alzheimer’s Association.

RESEARCH AND SCHOLARLY ACTIVITIES Dr. Janice Knoefel remains the co-investigator on a NIH-funded grant focused on Imaging and the Development of Memory Strategies in Aging.

Dr. Carla Herman is a regular reviewer for Medical Technologies that Reduce Health Disparity, NIBIB, NIH.

Dr. Dennis Villareal is PI of NIH grant R01AG11376 on weight loss and exercise in obese elderly and Co-I of VA Merit grant CX000424 on pharmacogenetics of response to testosterone therapy. He is on the editorial board for Journal of Nutrition in Health and Aging and Journal of Nutrition in Geriatrics and Gerontology.

Dr. Dennis Villareal continues as regular/standing member of NIH-Clinical and Integrative Diabetes and Obesity Study Section. He has been appointed to the DSMB for the Look AHEAD multicenter NIH trial and he serves as Chairperson of the Research and Development Committee of the NMVAHCS and board of directors of BRINM.

CLINICAL OPERATIONS Dr. David Hemphill was appointed Medical Director for Heritage Hospice.

Dr. Sandra Qaseem serves as Medical Director of Alliance Home Health and leads the Home Visit Program.

Dr. Donna Jean Parker is Director of the Home Based Primary Care Program at the VA.

Dr. Carla Herman serves on the Medical Advisory Committee for Amerigroup Community Care, Albuquerque.

Dr. April Volk is Director of the Palliative Care Program at the VA

Dr. Ivan Correa is Director of the Community Living Center at the VA

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COMMUNITY ACTIVITIES Drs. Janice Knoefel and Carla Herman serve on the NM Taskforce to develop the New Mexico State Plan for Alzheimer’s Disease.

ADMINISTRATION Dr. Anne Simpson serves as Rust Professor and Director, University of New Mexico Health Sciences Center for Ethics and the Associate Vice President for African American Health and Director of the Center of Excellence for African American Health.

HONORS AND AWARDS Dr. Villareal was speaker at Geriatric Medicine Grand Rounds at University of Colorado, Denver, FNIH-NIA-FDA Sarcopenia Consensus Summit in Baltimore, IANA Meeting in ABQ, GRECC meeting in Little Rock, AR, and Biology of Aging Joint AAG, GSA, and AFAR meeting in Boston, MA.

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

EDUCATION The Palliative Medicine Fellowship will expand to 2 fellows in July 2013.

RESEARCH AND SCHOLARLY ACTIVITIES Drs. Lisa Marr and Esme Finlay have developed a research collaboration with Holly Prigerson “Coping with Cancer II”, National Cancer Institute, 2012-2013.

CLINICAL OPERATIONS The Division faculty is working to develop the Medical Directorship for the Corrales Senior Living Community. This project, which plans to open in 2013, will include a 60-bed skilled nursing unit, a 40-bed memory care center and 40-bed assisted living as well as independent living.

Future plans at the VA include establishment of a 30-bed nursing home separate from the VA Medical Center. Also a new research building will be erected as part of the Center for Cellular and Molecular Medicine, which will include ~1000 sq feet of research lab for basic research (Dr. Villareal).

APPOINTMENTS FACULTY Name Title Effective date Ivan Correa, MD VAMC Acting Medical Director Community Living Center. 11/21/2011 Assistant Professor of Medicine.

STAFF None

SEPARATIONS FACULTY Name Title Effective date Jeremiah Kelly, MD Professor of Medicine 6/30/2012

STAFF None

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PUBLICATIONS OF THE DIVISION AND FACULTY

Janice Knoefel, M.D., MPH 1. Albert ML and Knoefel JE (Eds) The Clinical Neurology of Aging. 3rd Ed, Oxford University Press, New York, 2011.

Lisa Marr, M.D. 1. Marr LA, Neale D, Wolfe V and Kitzes J. Confronting Myths: The Native American experience in an academic inpatient palliative care consultation program. J Palliat Med. 2012 Jan;15(1):71-6. Epub 2012 Jan 13 2. Marr LA. The Bearer of Bad News. J Palliat Med. 2011 Mar;14(3):369-70

Devon Neale, M.D. 1. Marr L, Neale D, Wolfe V, Kitzes J. Confronting Myths: The Native American Experience in an Academic Inpatient Palliative Care Consultation Program. Journal of Palliative Medicine. 2012 Jan;15(1):71-6 Epub 2012 Jan 13

Dennis Villareal, M.D. 1. Weiss, E, Villareal DT. Ehsani A, Fontana L, and Holloszy JO. Dehydroepiandrosterone replacement therapy in older adults improves indices of arterial stiffness. Aging Cell 2012 [Epub ahead of print] 2. Armamento-Villareal R, Sadler C, Napoli N, Shah K, Chode S, Sinacore DR, Qualls C, and Villareal DT. Weight loss in obese older adults increases serum sclerostin and impairs hip geometry but both are prevented by exercise training. J Am Bone Miner 27:1215-21; 2012 3. Smith GI, Villareal DT, Sinacore DR, Shah K, Mittendorfer B. Muscle protein synthesis response to exercise training in obese, older men and women. Med Sci Sports Exerc. 44:1259-66; 2012 4. Murphy JC, McDaniel JL, Mora K, Villareal DT, Fontana L, Weiss EP. Preferential reductions in intermuscular and visceral adipose tissue with exercise-induced weight loss compared with calorie restriction. J Appl Physiol. 112:79-85; 2012. 5. Bugg JM, Shah K, Villareal DT, Head D. Cognitive and neural correlates of aerobic fitness in obese older adults. Exp Aging Res 38: 131-45; 2012 6. Niekamp K, Zavorsky GS, Fontana L, McDaniel JL, Villareal DT, Weiss EP. Systemic acid load from the diet affects maximal exercise respiratory exchange ratio. Med Sci Sports Exer 44:709-15; 2012 7. Villareal DT, Smith G, Shah K, Mittendorfer, B. Effect of weight loss on the rate of muscle protein synthesis during fasted and fed conditions in obese older adults Obesity (Silver Spring). 2011 Sep 22. [Epub ahead of print] 8. Wice BM, Reeds DN, Tran H, Crimmins DL, Patterson BW, Dunai J, Wallendorf MJ, Ladenson JH, Villareal DT, and Polonsky KS. Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance, but not type2 diabetes. Diabetes 61:1793-800; 2012 9. ShahK, Armamento-Villareal,R, Parimi,N, Chode,S, Sinacore,D.R, Hilton,T.N, Napoli,N, Qualls,C. and Villareal, DT. Exercise training in obese older adults prevents increase in bone turnover and attenuates decrease in hip BMD induced by weight loss despite decline in bone-active hormones. J Bone Miner Res 12:2851-2859; 2011 10. Villareal DT, Chode S, Parimi N, Sinacore DR, Hilton T, Armamento-Villareal R, Napoli N, Qualls C, Shah K. Weight loss, exercise, or both and physical function in obese older adults. N Engl J Med 364:1219-29, 2011 11. Weiss EP, Villareal DT, Fontana L, Han DH, Holloszy, JO. Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans. Aging (Albany NY) 5:533- 42; 2011 12. Villareal DT, Kotyk J, Armamento-Villareal R, Kenguva V, Seaman P, Shahar A, Wald M, Kleerekoper M, Fontana L. Reduced bone mineral density is not associated with significantly reduced bone quality in men and women practicing long-term calorie restriction with adequate nutrition. Aging Cell 10:96-102, 2011

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OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

Carla Herman, M.D., MPH JOURNAL/EDITORIAL REVIEWER  Annals of Internal Medicine, 1992 - ongoing  Journal of the American Geriatrics Society, 1995- ongoing  Editor for Healthwise

COMMUNITY OUTREACH  Board Member, Great West American Cancer Society

Dennis Villareal, M.D. EDITORIAL BOARD  International Journal of Osteoporosis and Metabolic Disorders (2006-)  Journal of Nutrition in Geriatrics and Gerontology (2008-present)

AD HOC REVIEWER OR EDITORIAL CONSULTANT  Alzheimer’s Disease and Related Disorders  American Journal of Physiology, Endocrinology & Metabolism  American Journal of Clinical Nutrition  Annals of Internal Medicine  Archives of Internal Medicine  Calcified Tissue International  Clinical Nutrition  Diabetes  Journal of Clinical Endocrinology & Metabolism  Journal of Gerontology: Biologic and Medical Science  Journal of the American Geriatrics Society  Obesity Research  Treatments in Endocrinology

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OUTSIDE SPONSORED RESEARCH

Project Faculty Sponsor Name Project Title Sponsor Number Start Stop F A Direct Total type Alliance Home Health Alliance Home Herman, Carla J. Clinical PSA-10-59 2/21/2011 2/20/2012 0 32,640 32,640 Care, LLC Healthcare & Hospice Next Steps in Donald W Reynolds Herman, Carla J. Physicians' Training in Education DWRF/Herman 1/1/2012 12/31/2013 41,560 208,440 250,000 Foundation Geriatrics Teaching Motivation University of Herman, Carla J. Interviewing for Education 2011-2633 1/1/2012 12/21/2013 6,000 30,000 36,000 California, Irvine Geriatric Patients

Finlay, Esme National Cancer Coping with Cancer II Education RFA-CA-10503 6/1/12 8/31/12 6,226 12,210 18,438 Marr, Lisa Institute

HRSA-Health Resources and ACA-Choose Your Own Neale, Devon A. Education K01HP20456-01 9/1/2011 8/31/2012 5,555 69,436 74,991 Services Geri-Adventure Administration Exercise Interventions National Institute of during Voluntary Villareal, D Education R01 AG031176 4/1/09 3/31/15 1,819,333.00 Health Weight Loss in Obese Older Adults

Weight Loss and Nationals Institute of Villareal, D Exercise in Frail Obese Education R01 AG025502 01/01/05 12/31/12 1,075,000.00 Health Elderly Subjects CYPAI Gene and Pharmacogenetics of Villareal, D VA Merit Grant 1101 Clinical CX000424 10/01/10 09/30/14 496,805.00 response to Testosterone Therapy

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HEMATOLOGY/ONCOLOGY

ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Richard Lauer, MD Professor of Medicine Interim Chief, Division of Hematology/Oncology

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

EDUCATION There are currently 5 Hematology-Oncology Fellows in the training program. The fellowship is now a mandatory three total years, with an optional basic or laboratory research component, with board eligibility in both Hematology and Oncology.

The Division continues to organize the Wednesday morning Oncology Journal club, and the Wednesday morning didactic fellow/resident lecture series (led by Dr. Rabinowitz and more recently Dr. Fekrazad), the Tuesday afternoon UNM-wide ACOS-required Tumor Board (led by Drs. Mangalik and Lee), and the monthly City-Wide Hematology Meetings.

The Division continued to distribute to all Residents, Medical Students, and Fellows that rotate through any oncology clinic or ward the “Pocket Hematology-Oncology: Everything You Need to Know at Your Fingertips.” The Division holds two patient centered educations lectures per week for residents and fellows on topics in Hematology-Oncology, on Monday afternoon at 3-5 PM. We also have a monthly board review session scheduled for a Thursday 1:30-2:30 PM. Fellows also take annual in service exams to assess their knowledge base compared to national standardized tests.

RESEARCH AND SCHOLARLY ACTIVITIES The Division organizes and supervises all clinical oncology research for the UNM Health Science Center. In FY2011/12, the Division administrated a number of UNMCC protocols. These therapeutic trials are also open within the New Mexico Cancer Care Alliance, and thus accrue not only at UNM but also at numerous affiliated community sites. The Division supervised 218 accruals on therapeutic trials , with an additional 71 therapeutic accruals supervised by the Division at the community affiliate sites.

The Division published 30 peer-reviewed papers last year, in high quality journals such as the Journal of Clinical Oncology.

The Division continues to play a key leadership role in developing the flow of translational science from laboratory to clinic and back again, that is essential for the NCI P30 CCSG to the UNM Cancer Center.

CLINICAL OPERATIONS The UNM CRTC is one of 61 NCI-designated cancer centers in the US. The Division supervises all cancer care at the UNM Cancer Center, with Division faculty chairing the UNM HSC Oncology Committee, the policy setting body of the HSC, and serving as Oncology Physician in Chief for the UNM Hospital.

A number of key faculty left the Cancer Center this year. Dr. Julie Bauman and Dr. Robert Francis in 8/2012. Dr. Sampath will be leaving in 10/2012. We did hire Dr. David Lee as Radiation Oncologists.

Dr. Rabinowitz serves as the UNM Cancer Center’s Out-Patient Clinic Director, and Dr. Richard Lauer is the overall Chief Medical Officer for oncology efforts at the Cancer Center. He also is on the UNM Hospital Executive Medical Board, and serves as the Chair of the Oncology Committee for the UNM HSC.

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The Division in 2011/12 had responsibility for directing Hematology and Medical Oncology care in the Lovelace Sandia Health Care System, which comprises two area hospitals, Lovelace Downtown, and Women’s Hospital. This effort continues currently.

There are 8 multi-disciplinary clinics at the UNM Cancer Center. These are in breast (led by Dr. Royce), lung (led by Dr. Bauman), GI (led by Dr. Lee), hematologic malignancies (led by Dr. McGuire), gynecologic malignancies (led by Dr. Muller of OB-GYN), GU (led by Dr. Lauer), Radiation Oncology (led by Drs. Liem and Schroeder), and Phase I trials (led by Dr. Shaheen). These continue to function at a high level in the Cancer Center. Such clinics routinely include medical oncology, clinical trials coordinators, surgical oncology, radiology, and radiation oncology. The Division provides the leadership for these multi-disciplinary clinics. These multi-disciplinary clinics also have cognate clinical working groups that prioritize clinical trials and stimulate translational research in collaboration with the basic scientists of the Cancer Center.

The Division continues to supervise the Hematology-Oncology in-patient service at University Hospital, with Dr. Fa- Chyi Lee serving as the Medical Director both 5 East, the Oncology Floor and 3 East, the Hematology Floor.

The Division is organized into 6 Sections, Gastrointestinal Malignancies led by Dr. Lee, Aerodigestive Tumors, led by Dr. Bauman, Breast Cancer led by Dr. Royce, Radiation Oncology led by Dr. Schroeder, Experimental Therapeutic led by Dr. Shaheen, and Genitourinary Cancer led by Dr. Lauer.

ADMINISTRATION

Dr. Ian Rabinowitz continues to serve as UNM Cancer Center Out-Patient Clinical Director. Dr. Lee is Medical Director of 5E in UNMH, and 3E of UNM Hospital the oncology in-patient wards. Dr. Lee also serves on the Pharmacy and Therapeutics Committee of UNM Hospital. Dr. Lee sits on the UNMH Medical Directors Committee.

Dr. Royce is the Director of the Clinical Trials Office, the administrative office that organizes clinical oncology research. Dr. Bauman chairs the Protocol Review Committee of the UNM Cancer Center, which reviews all UNM oncology clinical protocols for scientific merit and feasibility. Dr. Shaheen is the Director of Experimental Therapeutics, which is the Phase I Trials effort, which will be responsible for building an early phase cancer Drug development Program at the Cancer Center.

Dr. Royce is the Medical Director of the New Mexico Cancer Care Alliance, which brings cutting edge clinical trials to the community.

Dr. Lauer is the Chief Medical Officer of the Cancer Center, and Oncology Physician-in-Chief for the UNM Hospital. He also now Chairs the Oncology Committee for the UNM HSC, and serves on the Executive Medical Committee of the UNM Hospital.

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

EDUCATION

We will strengthen and formalize the education efforts for residents and fellows on the UNMH Hematology- Oncology in-patient service. We will continue the significant efforts in didactic lectures for Fellows in Hematology- Oncology and Internal Medicine residents for board review.

RESEARCH AND SCHOLARLY ACTIVITIES Last year clinical research was designated as an area for improvement. That area has been markedly expanded, as described above. With the institution of the Clinical Research Committee to streamline and prioritize all clinical oncology research, and the recruitment of new clinical investigators, there was a marked increase in accruals to protocols, and in clinical publications. However, since the departure of key faculty the research effort has had to be adjusted.

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However, translating novel drugs discovered at UNM to clinical trials remains a complex goal. The challenge for this year is to continue to maintain the phase I program and recruitment of an experimental therapeutics researcher who can maintain and build this program has been unsuccessful.

Another major goal of the Divisional research this year is to increase the number of extra-mural peer-reviewed basic or translational research grants.

CLINICAL OPERATIONS The goal for last academic year was to fully incorporate the Lovelace Health plan patients into the Division’s oncology practice. The UNM Las Cruces clinic was stabilized with the recruitment of Drs. William Adler and Robert Francis. Unfortunately, Dr. Francis has subsequently resigned. We will continue to actively recruit a second physician.

A major goal for this coming year is the recruitment of a chief of the division. This process is already ongoing and a number of candidates were identified. To date we have been unsuccessful in recruiting a chief. This will afford the division stability and direction. The hiring of faculty to replace the clinical faculty who have left is also underway and a number of recruits have already been identified.

ADMINISTRATION The major goal for this next year is to completely integrate the new UN Cancer Center clinic building with the outreach clinics at Lovelace downtown, and Las Cruces, and the new faculty and electronic medical record. Finally, fully integrating the new section of Radiation Oncology into the Division has been an administrative priority for the Division. Fully integrating the Division, with its multiple complex Sections into a functional organism is imperative in order to achieve the above aims.

HONORS AND AWARDS The most significant achievement has been maintaining a functional division that has been able to serve patients from within the UNM system as well as from outside. This has been in an environment of diminishing numbers of faculty and decrease in the morale as a consequence of faculty attrition. The quality of care continues to be cutting edge.

APPOINTMENTS FACULTY Name Title Effective date Dr. David Lee Radiation Oncologist 8/13/2012

STAFF Name Title Effective date Mayra Vazquez Senior Operations Manager 10/3/2011

SEPARATIONS FACULTY Name Title Effective date Dr. Julie Bauman Assistant professor 8/17/2012 Dr. Robert Francis Assistant Professor 8/10/2012 Dr. Sagus Sampath Assistant Professor-R/O 10/4/2012

STAFF Name Title Effective date Daphne Tritle Unit Administrator 6/30/2012

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PUBLICATIONS OF THE DIVISION AND FACULTY

William Adler, M.D. N/A

Julie Bauman, M.D. 1. Bauman JE, Michel L, Chung CH. New promising molecular targets in head and neck squamous cell carcinoma. Current Opinion in Oncology 2012, In Press. 2. Oprea TI, Bauman JE, Bologa CG, Buranda T, Chigaev A, Edwards BS, Jarvik JW, Gresham HD, Haynes MK, Hjelle B, Hromas R, Hudson L, Mackenzie DA, Muller CY, Reed JC, Simons PC, Smagley Y, Strouse J, Surviladze Z, Thompson T, Ursu O, Waller A, Wandinger-Ness A, Winter SW, Wu Y, Young SM, Larson RS, Willman C and Sklar LA. Drug repurposing from an academic perspective. Drug Discovery Today: Therapeutic Strategies 2012, In Press. 3. Bauman J, Verschraegen C, Belinsky S, Muller C, Rutledge T, Fekrazad M, Ravindranathan M, Lee SJ, Jones D. A phase I study of 5-azacytidine and erlotinib in advanced solid tumor malignancies. Cancer Chemotherapy and Pharmacology 2012;69(2):547-54. 4. Zahn KL, Wong G, Bedrick EJ, Poston DG, Schroeder TM, Bauman JE. The relationship of calorie and protein intake to the severity of oral mucositis in head and neck cancer patients receiving radiotherapy. Head and Neck 2011, Jun 20, epub ahead of print.

Zoneddy Dayao, M.D. 1. Royce M, Z Dayao. Distant Metastases: A Surrogate Endpoint for Overall Survival in Early Breast Cancer? Breast Diseases: A Year Book Quarterly, 22 No 3: October-December 2011 2. Royce, MR, Dayao, Z. Commentary: Metformin and Incident Breast Cancer among Diabetic Women: A Population-Based Case–Control Study in Denmark, Breast Diseases: A Year Book Quarterly. Vol. 22, No. 4, January-March 2012 3. Candelaria-Quintana D, Dayao ZR, Royce ME. The role of antiresorptive therapies in improving patient care in early and metastatic breast cancer. Breast Cancer Res Treat. 2011 Oct 11. [Epub ahead of print]

M. Houman Fekrazad, M.D. 1. Anaplastic large cell-lymphoma associated with breast implants. World J of Plastic Surgery. (accepted for publication in 2011) 2. Cancer Metastasis: Biologic Basis and Therapeutics by David Lyden, Danny R. Welch and Bethan Psaila (2011) Cambridge University Press. “The biology and treatment of metastatic testicular cancer,” Ferkrazad MH, Hromas R, and Lauer R, P465.

Esme Finlay, M.D. N/A

Robert Francis, M.D. N/A

David Garcia, M.D. 1. Menzin J, Hoesche J, Friedman M, Nichols C, Bergman GE, Crowther M, Garcia DA, Jones C. “Failure to correct International Normalized Ratio and mortality among patients with warfarin-related major bleeding: an analysis of electronic health records.” J Thromb Haemost. 2012 Apr;10(4):596-605 2. Guyatt GH, Eikelboom JW, Gould MK, Garcia DA, Crowther M, Murad MH, Kahn SR, Falck-Ytter Y, Francis CW, Lansberg MG, Akl EA, Hirsh J. “Approach to outcome measurement in the prevention of thrombosis in surgical and medical patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.” Chest. 2012 Feb;141(2 Suppl):e185S-94S 3. Gould MK, Garcia DA, Wren SM, Karanicolas PJ, Arcelus JI, Heit JA, Samama CM; American College of Chest Physicians “Prevention of VTE in nonorthopedic surgical patients: Antithrombotic Therapy and

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Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.” Chest. 2012 Feb;141(2 Suppl):e227S-77S. 4. Dentali F, Marchesi C, Pierfranceschi MG, Crowther M, Garcia DA, Hylek E, Witt DM, Clark NP, Squizzato A, Imberti D, Ageno W. “Safety of prothrombin complex concentrates for rapid anticoagulation reversal of vitamin K antagonists. A meta-analysis.” Thromb Haemost. 2011 Sep;106(3):429-38 5. Alberts MJ, Bernstein RA, Naccarelli GV, Garcia DA. “Using Dabigatran in Patients With Stroke: A Practical Guide for Clinicians.” Stroke 2012 Jan;43(1):271-9 6. Garcia DA. “Benefits and risks of oral anticoagulation for stroke prevention in nonvalvular atrial fibrillation.” Thromb Res.2012 Jan;129(1):9-16. 7. Garcia DA, Quintana D. “Thrombosis and malignancy: a case-based review. Semin Hematol. 2011 Oct;48(4):259-63 8. Lopes RD, Horowitz JD, Garcia DA, Crowther MA, Hylek E. “Warfarin and acetaminophen interaction: a summary of the evidence and biological plausibility.” Blood. 2011 Dec 8;118(24):6269-73 9. Granger CB, Alexander JH, McMurray JJ, Lopes RD, Hylek EM, Hanna M, Al-Khalidi HR, Ansell J, Atar D, Avezum A, Bahit MC, Diaz R, Easton JD, Ezekowitz JA, Flaker G, Garcia DA, Geraldes M, Gersh BJ, Golitsyn S, Goto S, Hermosillo AG, Hohnloser SH, Horowitz J, Mohan P, Jansky P, Lewis BS, Lopez-Sendon JL, Pais P, Parkhomenko A, Verheugt FW, Zhu J, Wallentin L; the ARISTOTLE Committees and Investigators. “Apixaban versus Warfarin in Patients with Atrial Fibrillation.” N Engl J Med. 2011 Sep 15;365(11):981-92 10. Martinez L, Burnett A, Borrego M, Streeter JC, Townsend K, Garcia DA. “Effect of fondaparinux prophylaxis on anti-factor Xa concentrations in patients with morbid obesity.” Am J Health Syst Pharm. 2011 Sep 15;68(18):1716-22 11. Lopes RD, Garcia DA. “In people with atrial fibrillation unsuitable for warfarin, apixaban reduces the risk of stroke compared with aspirin, with no difference in major bleeding.” Evid Based Med. 2011 Dec;16(6):187-8 12. Moualla H, Garcia DA. “Vitamin K Antagonists - Current Concepts and Challenges.” Thromb Res. 2011 Sep;128(3):210-5 13. Lopes RD, Becker RC, Alexander JH, Armstrong PW, Califf RM, Chan MY, Crowther M, Granger CB, Harrington RA, Hylek EM, James SK, Jolicoeur EM, Mahaffey KW, Newby LK, Peterson ED, Pieper KS, Van de Werf F, Wallentin L, White HD, Carvalho AC, Giraldez RR, Guimaraes HP, Nader HB, Kalil RA, Bizzachi JM, Lopes AC, Garcia DA. “Highlights from the III International Symposium of Thrombosis and Anticoagulation (ISTA), October 14-16, 2010, São Paulo, Brazil.” J Thromb Thrombolysis. 2011 Aug;32(2):242-66

Richard Lauer, M.D. 1. Cancer Metastasis: Biologic Basis and Therapeutics by David Lyden, Danny R. Welch and Bethan Psaila (2011) Cambridge University Press. “The biology and treatment of metastatic testicular cancer,” M Fekrazad MH, Hromas R, and Lauer R, P465.

Fa-Chyi Lee, M.D. 1. Lee FC. Int J Dermatol. Longterm clinical remission of oral and cutaneous pemphigus with thalidomide. 50(9). 1120-3. Sep 2011.

Benny Liem, M.D. N/A

Aroop Mangalik, M.D. N/A

Yoshihiro Matsumoto, Ph.D. N/A

Elizabeth McGuire, M.D. N/A

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Yehuda Patt M.D. N/A

Dulcinea Quintana, M.D. 1. Garcia D, Quintana D. Thrombosis and malignancy: a case-based review. Seminars in Hematology. 2011 Oct. 2. Candelaria-Quintana D, Dayao ZR, Royce ME. The role of anti-resorptive therapies in improving patient care in early and metastatic breast cancer. Breast Cancer Res Treat. 2011 Oct 11. [Epub ahead of print]

Ian Rabinowitz, M.D. 1. Verschraegen CF, Arias-Pulido H, Lee SJ, Movva S, Cerilli LA, Eberhardt S, Schmit B, Quinn R, Muller CY, Rabinowitz I, Purdy M, Snyder D, Bocklage T. Phase IB study of the combination of docetaxel, gemcitabine, and bevacizumab in patients with advanced or recurrent soft tissue sarcoma: the Axtell regimen. Ann Oncol. 2011 Jul 11. [Epub ahead of print]

Melanie Royce, M.D., Ph.D. 1. Candelaria-Quintana D, Dayao ZR, Royce ME. The Role of Antiresorptive Therapiess in Improving Patient Care in Early and Metastatic Breast Cancer. Breast Cancer Res Treat. 2012 Apr;132(2):355-63. Epub 2011 Oct 11. PMID: 21987034. 2. Royce ME and Dayao Z. Distant metastases: a surrogate endpoint for overall survival in early breast cancer? Breast Diseases: A Year Book Quarterly, October-December 2011: 22 (3), 249-252. 3. Livingston RB, Barlow WE, Kash JJ, Albain KS, Gralow JR, Lew DL, Flaherty LE, Royce ME, Hortobagyi GN. SWOG S0215: A Phase II study of docetaxel and vinorelbine plus filgrastim with weekly trastuzumab for HER2-positive, stage IV breast cancer. Breast Cancer Res Treat. 2011 Aug 9. [Epub ahead of print] PMID:21826527 4. Guo H, Lu J, Hathaway H, Royce ME, Prossnitz ER, Miao Y. Synthesis and evaluation of novel gonadotropin-releasing hormone receptor-targeting peptides. Bioconjug Chem. 2011 Aug 17; 22(8):1682- 9. Epub 2011 Jul 20. PMID: 21749045 5. Wallace AM, Rosenberg RD, Royce ME. Surgery. Bone scan demonstration of osteoblastic tumor of the breast. 150(1). 135-6. Jul 2011.

John Saiki, M.D. 1. Saiki, JH. Lessons from My Patients about Living with a Serious Illness, Medical Muse; Vol.16, No.1: Spring 2011

Annahita Sallmyr, Ph.D. N/A

Sagus Sampath, M.D. 1. Sampath S, Schultheiss TE, Hitchcock YJ, et al. Int J Radiat Oncol Biol Phys. Pre-operative radiotherapy versus post-operative radiotherapy in soft-tissue sarcoma: multi-institutional analysis of 821 patients. 81(2). 498-505. Oct 2011. 2. Sampath S, Gaffney DK. Best Prac Res Clin Obstet Gynaecol. Role of Radiotherapy Treatment of Uterine Sarcoma. Jul 2011. [Epub ahead of print]

Thomas Schroeder, M.D. N/A

Montaser Shaheen, M.D. N/A

Amy Tarnower, M.D. N/A

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Alan Tomkinson, Ph.D. 1. Della-Maria J, Zhou Y, Tsai MS, Kuhnlein J, Carney JP, Paull TT, Tomkinson AE. J Biol Chem. Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway. 286(39). 33845-53. Sep 2011. Epub 2011 Aug 3. PMID: 21816818 2. Odell ID, Barbour JE, Murphy DL, Della-Maria JA, Sweasy JB, Tomkinson AE, Wallace SS, Pederson DS. Mol Cell Biol. Nucleosome disruption by DNA ligase III-XRCC1 promotes efficient base excision repair. 31(22). 4623-32. Nov 2011. Epub 2011 Sep 19: PMID: 21930793 3. Grob P, Zhang TT, Hannah R, Yang H, Hefferin ML, Tomkinson AE, Nogales E. Electron microscopy visualization of DAN-protein complexes formed by Ku and DNA ligase IV. Nov 2011. Epub 2011 Nov 15. PMID: 22088982 4. Tseng HM, Shum D, Bhinder B, Escobar S, Veomett NJ, Tomkinson AE, Gin DY, Djaballah H, Scheinberg DA. Assay Drug Dev Technol. A high-throughput scintillation proximity-based assay for human DNA ligase IV. Dec 2011. PMID: 22192310 5. Tobin LA, Robert C, Nagaria P, Chumsri, S, Twaddell W, Ioffe OB, Greco GE, Brodie AH, Tomkinson AE, Rassool FV. Mol Cancer Res. Targeting abnormal DAN repair in therapy-resistant breast cancers. Dec 2011. Epub ahead of print: PMID: 22112941

Hui Yang, Ph.D. N/A

OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

William Adler, M.D.  (Founding member, Breast Tumor Working Group 2011-present) Memorial Medical Center, Las Cruces, NM. Monthly prospective breast cancer case reviews with radiology, surgery and pathology

Julie Bauman, M.D. National Cancer Institute  Eastern Cooperative Oncology Group, Head and Neck Core Committee (2008 - present)  Recurrent/Metastatic Task Force, NCI Head and Neck Cancer Steering Committee (2011 – present)  Chair, HPV/Immunotherapy Subcommittee

Zoneddy Dayao, M.D. N/A

M. Houman Fekrazad, M.D. N/A

Esme Finlay, M.D.  Ad-hoc Reviewer: Journal of Clinical Oncology (2012- present)  Chair Oncology Special Interest Group (SIG), American Academy of Hospice and Palliative Medicine; Oversee SIG activities, and select and review SIG presentations for annual meetings (2012-2013)  Chair-elect Oncology SIG, American Academy of Hospice and Palliative Medicine; Participated in leadership activities for SIG including review of SIG presentations for annual meetings (2011-2012)

Robert Francis, M.D. N/A

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David Garcia, M.D. N/A

Richard Lauer, M.D. N/A

Fa-Chyi Lee, M.D.  Physician Reviewer: New Mexico Medical Review Association

Benny Liem, M.D. N/A

Aroop Mangalik, M.D. N/A

Yoshihiro Matsumoto, Ph.D. N/A

Elizabeth McGuire, M.D. N/A

Yehuda Patt, M.D. N/A

Dulcinea Quintana, M.D. N/A

Ian Rabinowitz, M.D. AD HOC REVIEWER  American Journal of Hematology  Annals of Oncology  Internet Journal of Oncology

Melanie Royce, M.D., Ph.D.

 Member, External Advisory Committee, Fred Hutchinson Cancer Research Center P50 grant award from NCI’s Centers for Population Health and Health Disparities, January 2010 - present  Member, NCI Breast Cancer Steering Committee (BCSC), March 2009 – present  Member, Outcomes and Comparative Effectiveness Committee, SWOG, May 2011 – present  Member, Breast Committee, SWOG, March 2004 – present  Member, SWOG Breast Working Group Committee, April 2010 – present  NIH Grant reviewer, Special Emphasis Panel (SEP) Loan Repayment Program (LRP, L30 grants), 2010 – present

John Saiki, M.D. N/A

Annahita Sallmyr, Ph.D. N/A

Sagus Sampath, M.D. N/A

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Thomas Schroeder, M.D. N/A

Montaser Shaheen, M.D. N/A

Amy Tarnower, M.D. N/A

Alan Tomkinson, Ph.D. N/A

Hui Yang, Ph.D. N/A

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OUTSIDE SPONSORED RESEARCH

Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total

ECOG Eastern Eastern Cooperative Non-Mission Bauman, Julie E. Cooperative PSA-UNM-00 9/1/2006 8/31/2011 0 0 0 Oncology Group Specific Oncology Group New Mexico Cancer Care Clinical Trial Bauman, Julie E. Research CBP 08-01 11/3/2008 11/2/2013 19,615 78,459 98,074 Alliance Phase I & II New Mexico Cancer Care Clinical Trial Bauman, Julie E. Research OSI3602s 1/29/2009 1/28/2014 8,125 32,500 40,625 Alliance Phase II New Mexico Cancer Care Clinical Trial Bauman, Julie E. Research CP13-0811 7/15/2009 7/31/2014 27,994 111,976 139,970 Alliance Phase II New Mexico Cancer Care Clinical Trial Bauman, Julie E. Research #H3E-US-S130 9/8/2009 9/30/2014 28,255 113,020 141,275 Alliance Phase II New Mexico Cancer Care Clinical Trial Bauman, Julie E. Research OSI4641s 6/1/2009 6/1/2012 12,387 49,548 61,935 Alliance Phase II New Mexico Cancer Care Clinical Trial 3066K1-2264(same Bauman, Julie E. Research 11/1/2009 12/30/2012 12,387 49,548 61,935 Alliance Phase II as OSI4641s) New Mexico Cancer Care Clinical Trial Bauman, Julie E. Research 14295 1/13/2010 1/31/2013 7,339 29,358 36,697 Alliance Phase III New Mexico Cancer Care Clinical Trial Bauman, Julie E. Research CUDC-101-102 8/17/2010 8/17/2015 24,750 99,001 123,751 Alliance Phase I New Mexico Cancer Care Clinical Trial Bauman, Julie E. Research A8081014 12/13/2010 12/12/2015 20,985 83,940 104,925 Alliance Phase III New Mexico Cancer Care Clincial Trail Bauman, Julie E. Research #ARQ197-A-U302 1/20/2011 1/20/2016 15,375 61,501 76,876 Alliance Phase III New Mexico Cancer Care Clinical Trial Bauman, Julie E. Research A80810005 3/22/2011 3/31/2016 6,338 25,352 31,690 Alliance Phase II Fekrazad, New Mexico Cancer Care Clinical Trial Research TR321 8/31/2010 8/31/2013 17,472 69,891 87,363 Mohammad Alliance Phase III New Mexico Cancer Care Clinical Trial Garcia, David A. Research ATI-5923-CLN-505 6/27/2008 6/26/2013 15,149 60,597 75,746 Alliance Phase II New Mexico Cancer Care Clinical Trial Bridge/U01HL0872 Garcia, David A. Research 7/15/2009 6/30/2014 80,800 160,000 240,800 Alliance Phase III 29 Clinical Trial - Garcia, David A. Bristol-Myers Squibb, Inc. Research CV185030 4/13/2011 4/12/2012 0 0 0 Phase III

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Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total Jones, Jr, Dennie New Mexico Cancer Care Clinical Trial Research 20030185 7/17/2006 8/1/2011 9,520 38,080 47,600 V. Alliance Jones, Jr, Dennie New Mexico Cancer Care Clinical Trial Research AVF3991n 4/19/2011 4/18/2012 224 896 1,120 V. Alliance Phase IV Jones, Jr, Dennie New Mexico Cancer Care Clinical Trial Research I1Y-MC-JFBD 10/26/2009 10/31/2014 9,330 37,318 46,648 V. Alliance Phase II New Mexico Cancer Care Clinical Trial Lee, Fa-Chyi Research AMP 019 2/7/2008 2/6/2013 5,740 22,961 28,701 Alliance Phase II NSABP(National Surgical Clinical Trial NSABP-TIND 228 Lee, Fa-Chyi Research 1/1/2009 7/31/2011 35,500 142,000 177,500 Adjuvant Breast/Bowel Proj Phase III EFC10262

North Central Cancer Clinical Trial Lee, Fa-Chyi Research N0147 8/18/2008 12/31/2012 5,000 20,000 25,000 Treatment Group (NCCTG) Phase III New Mexico Cancer Care Clinical Trial Lee, Fa-Chyi Research APO4565g 5/7/2009 5/1/2012 5,751 23,005 28,756 Alliance Phase I Clinical Trial Lee, Fa-Chyi Amgen, Inc. Research 109499 7/14/2009 7/13/2014 24,083 96,330 120,413 Phase II New Mexico Cancer Care Clinical Trial Lee, Fa-Chyi Research Protocol 12917 9/21/2009 9/20/2014 5,612 22,451 28,063 Alliance Phase III New Mexico Cancer Care Clinical Trial Lee, Fa-Chyi Research RAD001R2301 6/23/2009 6/1/2012 5,880 23,520 29,400 Alliance Phase III PO3100048698Prtcl New Mexico Cancer Care Clinical Trial Lee, Fa-Chyi Research 20080259Cnt12793 4/12/2010 4/30/2015 2,848 11,393 14,241 Alliance Phase III 3 New Mexico Cancer Care Clinical Trial Lee, Fa-Chyi Research #AB 08026 7/8/2010 7/7/2011 17,678 70,710 88,388 Alliance Phase III New Mexico Cancer Care Clinical Trial Lee, Fa-Chyi Research Perifosine 343 2/1/2010 6/30/2012 18,661 74,646 93,307 Alliance Phase III New Mexico Cancer Care Clinical Trial Lee, Fa-Chyi Research CO-101-001 11/16/2010 11/15/2015 21,701 86,804 108,505 Alliance Phase II New Mexico Cancer Care Clinical Trial Lee, Fa-Chyi Research TPU-S1303 2/21/2011 2/21/2016 7,500 30,003 37,503 Alliance Phase III New Mexico Cancer Care Clinical Trial Lee, Fa-Chyi Research 287-11-201 2/1/2011 4/30/2014 6,747 26,990 33,737 Alliance Phase II

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Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total New Mexico Cancer Care Clinical Trial Lee, Fa-Chyi Research 20050181 8/3/2010 8/2/2011 2,400 9,600 12,000 Alliance Phase III

New Mexico Cancer Care Clinical Trial Non-Mission Libby, Edward N. 088MK0683 9/24/2009 11/30/2011 5,644 22,579 28,223 Alliance Phase III Specific

Stem Cell National Marrow Donor Libby, Edward N. Therapeutic Research CIBMTR#11079 7/2/2007 7/1/2013 9,103 36,413 45,516 Program Outcomes Clinical Trial New Mexico Cancer Care Libby, Edward N. Agreement Research CV185-027-016 2/2/2011 2/1/2012 807 3,227 4,034 Alliance Phase II New Mexico Cancer Care Clinical Trial Libby, Edward N. Research CG53135-CLN-12 3/19/2011 3/18/2012 1,659 6,635 8,294 Alliance Phase II NSABP(National Surgical Mangalik, Aroop Clinical Trial Research PFED26-NMX-01 6/1/2011 5/31/2012 0 0 0 Adjuvant Breast/Bowel Proj

NSABP(National Surgical Clinical Trial Mangalik, Aroop Research TIND-228 B-43 11/1/2008 10/31/2013 675 2,700 3,375 Adjuvant Breast/Bowel Proj Phase III B-47 NSABP(National Surgical Mangalik, Aroop Study/Genentec Research B-47IND6667 1/1/2011 12/31/2016 10,287 41,150 51,437 Adjuvant Breast/Bowel Proj h Supplement New Mexico Cancer Care Clinical Trial IST0004000 Inst Patt, Yehuda Z. Research 4/28/2009 4/27/2012 38,220 152,880 191,100 Alliance Phase II 0820 New Mexico Cancer Care Clinical Trial Patt, Yehuda Z. Research CP12-20922 12/6/2010 11/30/2011 19,640 78,560 98,200 Alliance Phase III New Mexico Cancer Care Clinical Trial Patt, Yehuda Z. Research OX-05-024 12/6/2010 12/5/2011 4,542 18,171 22,713 Alliance Phase II New Mexico Cancer Care Clinical Trial Rabinowitz, Ian Research AT-101-CS-202 1/11/2008 1/10/2013 4,035 16,138 20,173 Alliance Phase II New Mexico Cancer Care Clinical Trial Rabinowitz, Ian Research AT-101-CS-205 3/21/2008 3/20/2013 5,801 23,203 29,004 Alliance Phase II Novartis Pharmaceuticals Clinical Trial Rabinowitz, Ian Research STI571 0106 Amd#3 1/1/2010 7/31/2012 1,067 5,335 6,402 Corporation Phase III New Mexico Cancer Care Clinical Trial - Rabinowitz, Ian Research GU09-145 11/30/2010 11/30/2015 16,966 67,867 84,833 Alliance Phase I & II Rasila, New Mexico Cancer Care Clinical Trial Clinical AP23573-07-302 1/23/2008 1/22/2013 19,975 79,900 99,875 Kanwaldeep K Alliance Phase III

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Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total Rasila, New Mexico Cancer Care Clinical Trial Research CEP-18083 5/14/2009 5/31/2014 21,156 84,627 105,783 Kanwaldeep K Alliance Phase III Rasila, New Mexico Cancer Care Clinical Trial Research 3066K1-1208 9/1/2009 4/30/2012 39,000 156,000 195,000 Kanwaldeep K Alliance Phase I/II Rasila, New Mexico Cancer Care Clinical Trial Research ET-C-002-07 2/26/2010 2/28/2015 26,693 106,773 133,466 Kanwaldeep K Alliance Phase III Rasila, New Mexico Cancer Care Clinical Trial Research OMB112517 2/15/2010 2/28/2015 2,913 11,654 14,567 Kanwaldeep K Alliance Phase III Rasila, New Mexico Cancer Care Clinical Trial Research C18083/3070 5/14/2009 5/31/2015 5,830 23,320 29,150 Kanwaldeep K Alliance Phase III Rasila, New Mexico Cancer Care Clinical Trial Research PX-171-009 6/21/2010 11/30/2011 16,740 66,960 83,700 Kanwaldeep K Alliance Phase III Rasila, New Mexico Cancer Care Clinical Trial Research OMB113676 7/23/2010 7/23/2015 15,668 62,672 78,340 Kanwaldeep K Alliance Phase III Rasila, New Mexico Cancer Care Clinical Trail Research MC0982 2/15/2011 2/15/2016 9,000 36,000 45,000 Kanwaldeep K Alliance Phase I/II Purchase Royce, Melanie E. CTRC Research Foundation Service Research 7580 8/1/2010 7/31/2011 1,431 7,156 8,587 Agreement New Mexico Cancer Care Royce, Melanie E. Clinical Trial Research 20050136 7/17/2006 9/1/2011 9,780 39,120 48,900 Alliance New Mexico Cancer Care Clinical Trial Royce, Melanie E. Research CA163131 4/1/2008 3/31/2013 14,000 56,000 70,000 Alliance Phase II New Mexico Cancer Care Clinical Trial Royce, Melanie E. Research A6181094 2/27/2008 2/26/2013 10,570 42,280 52,850 Alliance Phase III New Mexico Cancer Care Clinical Trial Royce, Melanie E. Research A6181099 5/16/2008 5/15/2013 13,008 52,034 65,042 Alliance Phase III New Mexico Cancer Care Clinical Trial Royce, Melanie E. Research CA163100 8/6/2008 8/5/2013 9,390 37,560 46,950 Alliance Phase II North Central Cancer Clinical Trial Royce, Melanie E. Research ALTTO N063D 4/11/2008 4/10/2013 14,996 59,985 74,981 Treatment Group (NCCTG) Phase III

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Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total

New Mexico Cancer Care Clinical Trial Royce, Melanie E. Research GP88 3/1/2009 2/28/2014 1,760 7,040 8,800 Alliance Phase III

ARRA-(NM MBCCOP) Research Supplement to NIH/National Cancer Promote Re- 3U10CA086780- Royce, Melanie E. Research 9/30/2009 9/29/2011 106,524 210,677 317,201 Institute Entry into 10S1 Biomedical and behavioral Research Careers New Mexico Cancer Care Clinical Trial - Royce, Melanie E. Research CRADY2301 4/10/2009 6/24/2014 22,319 89,274 111,593 Alliance Phase III New Mexico Cancer Care Clinical Trial- Royce, Melanie E. Research INST BrUOG-BR-213 10/1/2010 9/30/2011 0 0 0 Alliance Phase II NM Minority Based NIH/National Cancer Community Royce, Melanie E. Research 5U10CA086780-11 6/1/2010 5/31/2011 220,975 445,803 666,778 Institute Clinical Oncology Program New Mexico Cancer Care Clinical Trial Royce, Melanie E. Research 155-CL-036 4/1/2010 3/31/2015 15,838 63,348 79,186 Alliance Phase II New Mexico Cancer Care Clinical Trial Royce, Melanie E. Research BRE09-146 5/14/2010 5/31/2015 7,066 28,265 35,331 Alliance Phase II Clinical Trial Phase II- MRI Royce, Melanie E. Southwest Oncology Group Research CA32102 8/1/2010 7/31/2015 0 92,000 92,000 Diffusion Supplement New Mexico Cancer Care Clinical Trial BO22589/TDM4788 Royce, Melanie E. Research 8/17/2010 8/17/2015 17,335 69,343 86,678 Alliance Phase III G New Mexico Cancer Care Clinical Trial Royce, Melanie E. Research Bayer-12444 1/10/2011 1/10/2016 16,525 66,100 82,625 Alliance Phase III New Mexico Cancer Care Clinical Trail Royce, Melanie E. Research EGF 114299 12/17/2010 2/18/2018 27,675 110,700 138,375 Alliance Phase III

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Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total New Mexico Cancer Care Clinical Trial Sampath, Sagus Research ALD518-CLIN-009 6/23/2011 6/30/2016 22,364 89,450 111,814 Alliance Phase II

Schroeder, New Mexico Cancer Care Clinical Trial Research PrTk03 6/17/2011 6/17/2016 1,971 7,884 9,855 Thomas M. Alliance Phase III Clinical Trial Shaheen, New Mexico Cancer Care Agreement Research 11Y-MC-JFBA 5/24/2007 5/23/2012 36,981 147,922 184,903 Montaser Alliance Phase I Shaheen, New Mexico Cancer Care Clinical Trial Research CZ48-01 9/15/2008 9/14/2013 16,310 65,239 81,549 Montaser Alliance Phase I Shaheen, New Mexico Cancer Care Clinical Trial Research 20080016 8/31/2009 8/31/2014 25,380 101,520 126,900 Montaser Alliance Phase I Verschraegen, New Mexico Cancer Care Clinical Trial Clinical CA184045 1/30/2008 1/29/2013 1,000 4,000 5,000 Claire F. Alliance Phase II

Verschraegen, New Mexico Cancer Care Clinical Trial Non-Mission PX-866-002 1/31/2011 1/31/2016 12,966 51,862 64,828 Claire F. Alliance Phase I and II Specific

Pilot Study, immunotheraph Verschraegen, Mesothelioma Applied y in patients Research 7760/Verschraegen 1/1/2007 12/31/2011 0 0 0 Claire F. Research Foundation, Inc. with Peritoneal & Pleural Mesothelioma Verschraegen, New Mexico Cancer Care Clinical Trial Research A6181065 4/13/2011 9/30/2011 484 1,937 2,421 Claire F. Alliance Phase III

Verschraegen, New Mexico Cancer Care Clinical Trial Research Protocol 0701C 8/14/2008 3/31/2011 5,165 20,660 25,825 Claire F. Alliance Phase I

Verschraegen, New Mexico Cancer Care Clinical Trial Research IPM2002 10/22/2008 10/21/2013 22,797 91,186 113,983 Claire F. Alliance Phase II

Verschraegen, New Mexico Cancer Care Clinical Trial Research LX01-315 12/2/2008 12/1/2013 18,266 73,064 91,330 Claire F. Alliance Phase III

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Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total Verschraegen, New Mexico Cancer Care Clinical Trial Research CA 184-029 1/12/2009 1/11/2014 16,565 66,260 82,825 Claire F. Alliance Phase III

Verschraegen, New Mexico Cancer Care Clinical Trial Research #005/05 2/24/2010 9/30/2011 9,149 36,596 45,745 Claire F. Alliance Phase III

Verschraegen, New Mexico Cancer Care Clinical Trial Research IPM3001 7/20/2010 7/20/2015 20,392 81,570 101,962 Claire F. Alliance Phase III

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HOSPITAL MEDICINE ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Kendall Rogers, MD Associate Professor of Medicine Chief, Division of Hospital Medicine

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

This has been a challenging first year as a Division of Hospital Medicine. We have dealt with continued short staffing and the additional burden of hiring and planning for the development of a new section of hospital medicine with 10 faculty at SRMC which successfully opened at the end of the year. Even with these challenges we have continued to be actively involved in process improvement projects and educational activities.

EDUCATION  The Division continues to provide significant levels of medical student and resident education. This includes tutorials, Phase 2 lecture series, BATCAVE simulation training. We have continued our work in BATCAVE simulation training  We continue to prioritize quality and safety education. We offer the Informatics, Medical Economics, and leadership Elective with high levels of resident participation (Between a third to half of all residents complete this elective over their residency.  Phase 2 lecture series and tutorials  We continue our weekly Hospital Medicine Best Practices lecture series which is attending by faculty, residents, fellows, students, case management, and members from other divisions and departments. This is an excellent educational venue for hospital medicine topics, but also provides experience, skills, and feedback in educating on a regular basis for each of our faculty.

RESEARCH AND SCHOLARLY ACTIVITIES  Increased number of submissions and acceptances over the past 3 year average: 1) Our IRB approved  Projects increased by 68% 2) The number of National meeting abstracts doubled and 3) We had 3 manuscripts published. In the past, our average was only 1.  We have instituted a monthly research mentorship meeting where faculty can come to propose and seek feedback and advice on projects. This also allows members to hear what others are working on and promotes the importance of these activities in the division.  We have had a number of chapters and a textbook submitted for this year, as well as Cochrane reviews.

CLINICAL OPERATIONS  We lost our mid-level who was leading our discharge clinic and this position has not been replaced as of now. This is a challenge in assuring safe and quick follow-up for our patients.  We have again reached new peaks to our census levels and have had to find ways to accommodate, especially in the face of short staffing. We have developed action plans and models for these extreme patient censuses that include additional patient loads for attendings on resident services, non-resident services, and a backup call process. We continue to try to have sufficient staffing to respond to these acute needs.  Due to short staffing each of our hospitalists has been taking significant additional work to ensure coverage of all teams. While this is a necessary function at this time, it cannot be a long term solution as we have already lost staff this year listing this as one of the factors.  We have continued to focus on core quality activities including VTE prophylaxis, Glycemic Control, and Care Transitions.

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 Our Hospital Medicine Best Practice meetings still serve as a forum to develop new clinical guidelines and identify issues. Each meeting has an expectation to address a system issue or develop a process to ensure standardization of processes. This has led to the development of written guidelines, electronic order sets, and other education activities and process changes in the hospital.  We perform 100% open mortality reviews on all deaths that occur on the hospital medicine service which helps direct and identify trends in safety and process issues in our system.

COMMUNITY ACTIVITIES  2 of our members are involved in providing Boy Scout physical exams.  We have participated in AHRQ state wide mentorship initiatives around VTE and continue to have relationships with these outlying hospitals, providing protocols and materials to improve the care they provide their patients.

ADMINISTRATION  Major achievements included became a Division of Hospital Medicine and adding a Section of Hospital Medicine at SRMC and incorporating the VA Section of Hospital Medicine. This increased our total faculty and staff to almost 40 members.  Added an administrative role  We were able to increase pay for hospitalist with a goal of 50% AAMC to help with retention and recruitment  Our online wiki continues to be our primary form of communication and standardization. It continues to grow each year with wider audiences. We have most processes described in detail and it is updated almost daily by many participants. The wiki forms a written culture of transparence and process improvement as well as serving as an educational resource.  We have begun producing a monthly practice report which includes minutes and major decisions made at each of our hospitalist meetings, and synopsis of major teaching points and process changes from our best practice meetings.  We continue to have monthly business meetings, monthly executive business meetings, monthly mortality meetings, and monthly work group meetings. Our hospitalists are engaged in meetings 2-3 times every week which adds to the cohesiveness and productivity of the group.

HONORS AND AWARDS  We were recognized for our work in DVT by winning the DVTeam Award, which was presented in Boston.  We also were also recognized for an honorable mention for the 2011 National Association of Public Hospitals and Health Systems “Improving Patient Safety Award” for our work in glycemic control.

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

Staffing and retention of staff continue to be our main challenges in the coming year. The amount of clinical work to existing staff due to short staffing is stifling our research, quality, and to some extent educational missions. We must better retain our staff and be more successful in recruiting them. This includes both addressing salary discrepancies with community as well as addressing the system issues that make it less gratifying to work at UNM. Efforts are being made in each of these areas.

Our next major challenge is converging the 3 hospital medicine sections/locations (UNM, VA, and SRMC) into common activities and practices. This has begun with Chief’s meetings and common goal setting, but this must be expanded to include integration of our various faculty projects and activities. We are planning our first division retreat this year which will begin addressing this topic.

EDUCATION Goal to have best practices telecasted to VA and SRMC sites

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RESEARCH AND SCHOLARLY ACTIVITIES Staff needs more time to invest in research projects. We have young faculty with strong interest in these areas and we must foster their growth.

CLINICAL OPERATIONS As stated above, our primary issue is achieving full staffing and getting the necessary funding to retain and recruit faculty.

COMMUNITY ACTIVITIES Ongoing focus on community related outreach in addition to committee and education initiatives on both a local and national level

ADMINISTRATION We must consider an administrative structure change. We have had a significant burden with processing hiring and contracts in a timely manner.

HONORS AND AWARDS Recognition of Faculty and Staff for significant achievements on both a local and national level

APPOINTMENTS FACULTY Rishi Menon MD Assistant Professor 7/18/2011 Shelia Modi MD Assistant Professor 7/18/2011 Jens Langsjoen MD Assistant Professor 8/1/2011 Sivitri Aguiar MD Assistant Professor 9/1/2011 John Rush Pierce MD Vice Chair, Faculty Development 1/3/2012 Bryan Wood MD SRMC Assistant Professor 4/1/2012 Betty Newville MD SRMC Assistant Professor 4/1/2012 David Gonzales MD SRMC Section Chief, Assistant Professor 4/1/2012 Rebecca Bair MD SRMC Assistant Professor 6/1/2012 Nathaniel Collins MD Assistant Professor 6/13/2012

STAFF Laura Holder Administrative Assistant II 4/23/2012

SEPARATIONS FACULTY Jason Cohen MD Assistant Professor 8/30/2011 Erik Kraai MD Assistant Professor 6/30/2012 Leonard Noronha MD Assistant Professor 6/30/2012 Rishi Menon MD Assistant Professor 6/30/2012 Savitri Aguiar Assistant Professor 6/30/2012 Sepehr Khashaei Assistant Professor 6/30/2012

STAFF Mary Gomez Administrative Assistant II 11/18/2011

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PUBLICATIONS OF THE DIVISION AND FACULTY

Marcos Burgos, M.D. 1. Ahuja SD, Ashkin D, Avendano M, Banerjee R, Bauer M, Bayona JN, Becerra MC, BenedettiA, Burgos MV, et al.Multidrug Resistant Pulmonary Tuberculosis Treatment Regimens and Patient Outcomes: An Individual Patient Data Meta-analysis of 9,153 Patients. PLOSMedicine. 2012; 9 (8). 2. Lienhardt CL, Cook SV, Burgos MV et al., Eficacyand Safety of a 4-Drug Fixed Dose Combination regimen for the treatment of Pulmonary Tuberculosis (Study C): an international multicenter randomized controlled trial. JAMA. 2011; 305(14): 1415-23.

Rush Pierce, M.D. 1. Smalligan RD, Chua M, Pierce JR Jr, Urban RS. PreTest Medicine. Self Assessment and Review (13th ed). New York: McGraw Hill; 2012. 2. Eder M, Pierce JR Jr. Empowering busy clinical faculty to conduct and publish research: development of a research assistance unit (RAU) at a regional medical school campus. South Med J 2011;104(9):647-650. 3. Richardson JM, Pierce JR Jr, Lackan N. Attempts by one local health department to provide only essential public health services: a 10-year retrospective case study. J Public Health Manage Pract 2012;18(2):126- 131. 4. Pierce JR Jr, Chang B, Rogers KM, Jernigan JR, Fotieo DR, Kang H, Leverence RR. Redesign of an internal medicine ward rotation: operational challenges and outcomes. J Grad Med Educ 2012;4:97-100. 5. Parada A, Pierce JR Jr. How should alcoholic hepatitis be treated? The Hospitalist 2012:16(3):12-14. 6. Shirley M, Johnson E, Kang H, Pierce JR Jr. Fall-related injury in the hospital [abstract 69]. Society of Hospital Medicine, 04/02/2012, San Diego, CA. J Hosp Med 2012;7(Suppl 2):S48. 7. Ravi-Kumar S, Pierce JR Jr. Clinical vignette: Burkitt’s lymphoma mimicking ovarian cancer [abstract 349]. Society of Hospital Medicine, 04/03/2012, San Diego, CA. J Hosp Med 2012;7(Suppl 2):S221-2. 8. Shirley M, Johnson EF, Pierce JR Jr. Fall-related injury in the hospital is related to narcotic use but not age [abstract B88]. American Geriatrics Society, 05/03/2012, Seattle, WA. J Am Geriatrics Soc 2012;60:S103.

Kendall Rogers, MD 1. Mentored Implementation: Building Leaders and Achieving Results through a Collaborative Improvement Model. Maynard G; Budnitz T, Nickel W, Greenwald J, Kerr K, Miller J, Resnic J, Rogers K, Schnipper J, Stein J, Whitcomb W, Williams M. Journal on Quality and Patient Safety. 2012: Vol 38, No. 7, pp 201-310. 2. Co-Author of Textbook: Improving Outcomes with Clinical Decision Support: An Implementer’s Guide. Second Edition. Published by HIMSS, AMIA, AMDIS, SHM, and Scottsdale Institute. 3. Redesign of an internal medicine ward rotation for compliance with ACGME duty-hour restrictions: operational challenges, education effects and professional satisfaction. Journal of Graduate Medical Education. Ms. No. JGME-D-11-00092R2 4. Rogers KM, Matonti R, Hoeppner S. Improving glycemic control in the hospital with a multi-disciplinary quality improvement process. [abstract 199] J Hosp Med 2011;6(Suppl 2):S128.

OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

Marcos Burgos, M.D. INVITED LECTURES: INTERNATIONAL  Can we Treat Tuberculosis with Higher Doses of Rifampin and Shorten the Treatment to Less than 6 Months? Congreso Nacionalde Neumologia Y Cirugia de Torax, Cancun Mexico, April 2012.  Drug Resistant Tuberculosis: Present and Future. International Congress: Advances in Medicine, Policlinico Peruano Japones. Lima Peru, March 2012.  Can We Shorten the Treatment of Tuberculosis to Less than 6 months? Congreso Peruano De Enfermedades Infeciosasy Tropicales, Lima Peru, September 2011.

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INVITED LECTURES: REGIONAL OR NATIONAL  Pulmonarytuberculosis in HIV infected patients. ECHO project, Albuquerque, New Mexico,November 2012.  Tuberculosis a Global Problem: Perspectives and insights. Preventive Medicine Seminar, UNM SOM. December 1st, 2011.  US Border: Tuberculosis Epidemiology and Treatment. Unidos Binational Tuberculosis Conference, Las Cruces NM, November 15, 2011.  Can we shorten the treatment of tuberculosis? InfectiousDisease Division, Albuquerque, NM, October 2011.  Managing Tuberculosis in the Hemodialysis patient: Heatland National TB Center Webinar, San Antonio Texas. September 28, 2011.

JOURNAL/EDITORIAL REVIEWER  International Journal of Tuberculosis and Lung Disease

COMMUNITY OUTREACH  Advisory Council for the Elimination of Tuberculosis (ACET). National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention (CDC). January 2011-present.  Tuberculosis Elimination Workgroup. Advisory Council for the Elimination of Tuberculosis Centers for Disease Control and Prevention. 2011-present  Board Member, National Tuberculosis Controllers Association (NTCA). 2011-2012  Member U.S. Border Tuberculosis Consortium. 2010 – present.  Advisory Committee Heartland National Tuberculosis Center, San Antonio Texas, Member2009- Present  Medical Consultant, Heartland National TB Center, San Antonio Texas, 2009 – present  Member, Stop TB Working Group on DOTS-Plus for MDR-TB, World Health Organization. 2002-present

Rush Pierce, M.D. PROFESSIONAL AFFILIATIONS  American College of Physicians, New Mexico Chapter (Governing Council; Chair, Hospitalist Committee; Chair, Program Committee)  American College of Preventive Medicine (Education Committee)  American Geriatrics Society (Disaster Planning and Preparedness Special Interest Group)

Kendall Rogers, MD COMMUNITY OUTREACH  National Content Developer (NCD) Webinar Series for the Department of Health and Human Services’ Partnerships for Patients Featured Speaker: ‘VTE Prophylaxis Strategies’ (05/2012)

INVITED LECTURES: REGIONAL OR NATIONAL  Society of Hospital Medicine Annual Meeting – San Diego; Speaker: ‘Complexity Science in Healthcare’ (05/2012)  Updates in Internal Medicine Conference, Santa Fe Speaker: “Updates in Hospital Medicine’ (10/2011)  ACP New Mexico Regional Conference Speaker: ‘Update in Hospital Medicine 2011’ (10/2011)

JOURNAL/EDITORIAL REVIEWER  Journal of Hospital Medicine Reviewer

PROFESSIONAL AFFILIATIONS  Chair - Society of Hospital Medicine Health IT Executive Committee  Lead - Society of Hospital Medicine Glycemic Control Mentored Implementation Program  Co-chair - American College of Physician Executives Medical Education Task Force  Member-Society of Hospital Medicine Health Quality and Safety Committee  Member - Society of Hospital Medicine MOC Committee

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 Member - HIMSS Clinical Decision Support Committee  Member: Society of Hospital Medicine, American College of Physicians, Health Information and Management Systems Society, American College of Physician Executives, Society of General Internal Medicine, Association of Chiefs and Leaders in General Internal Medicine

Deepti Rao, MD INVITED LECTURES: REGIONAL OR NATIONAL  New Mexico Annual ACP conference

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OUTSIDE SPONSORED RESEARCH

Project Faculty Sponsor Name Project Title Sponsor Number Start Stop F A Direct Total type Tuberculosis Medical Burgos, New Mexico Department Care, Consultation & Education 11UNM/02.0048 7/1/2011 6/30/2012 5,165 93,908 99,073 Marcos of Health Education Services

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INFECTIOUS DISEASES

ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Thomas Byrd, M.D. Professor of Medicine Interim Chief, Division of Infectious Diseases

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

EDUCATION  Luong Nguyen successfully completed the Infectious Diseases fellowship program.  Kingsley Asare, Firas Aswad and Kari Yacisin entered the Infectious Diseases fellowship as first year fellows and successfully completed their first year of the program  Dr. Michelle Iandiorio presented numerous lectures on aspects of HIV care throughout the state of New Mexico and the Western Region of the United States  Dr. Susan Kellie presented numerous lectures on aspects of infection control throughout the state of New Mexico  The ID Division continued to participate in CME activities throughout NM, including the Advances in Internal Medicine Lecture series.  The ID Division faculty play a leadership role in medical student and resident education through involvement in Phase I tutorials, development of course curricula and organization/coordination of lecture series

RESEARCH AND SCHOLARLY ACTIVITIES  Division faculty as a whole published 12 articles in peer-reviewed journals  Dr. Samuel Lee successfully renewed his Department of Veterans Affairs MERIT Review Grant “Secreted virulence proteins and biofilm formation in Candida albicans”.  Dr. Robert Munk received his 13th consecutive award from National Institutes of Health, National Library of Medicine for “AIDS InfoNet”

CLINICAL OPERATIONS  Dr. Bruce Williams successfully renewed the Ryan White Title Part C/HMA 1 grant from the US Department of Health and Human Services funding HIV care at the Truman Street Clinic

COMMUNITY ACTIVITIES  Dr. Michelle Iandiorio participated in numerous sponsored events supporting AIDS awareness as well as adolescent health

ADMINISTRATION  Dr. Corey Tancik, a valued faculty member in the ID Division, passed away. Dr. Tancik was a superb clinician and medical educator. He had served in the role of ID Fellowship Director for many years and played a key role in the education of ID Fellows who graduated from the ID Fellowship program.  Dr. Greg Mertz retired as Infectious Diseases Division Chief and is now Emeritus Professor of Internal Medicine. He will be continuing his research activities and limited clinical activities on a part-time basis.  Dr. Thomas F. Byrd assumed the role of Interim Infectious Diseases Division Chief.  Two faculty searches were initiated.

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HONORS AND AWARDS  Michelle Iandiorio, M.D promoted to Associate Professor  Susan Kelly, M.D. promoted to Professor.  Samuel Lee, M.D. promoted to Professor.  Elaine Thomas, M.D. - One of 7 nominees for UNMHSC “Stellar Consultant Award”  Elaine Thomas, M.D. - Passed American Academy of HIV Medicine HIV Specialist Credentialing Exam

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

EDUCATION  Dr. Sarah Allen, a new faculty member of the ID Division will assume the position of ID Fellowship Director  The ID Division plans to continue to have a major role in medical student education at UNM through involvement in Phase I tutorials, development of course curricula and organization/coordination of lecture series  The ID Division will continue to be recognized throughout the state as playing a major role in HIV and hepatitis C clinical care and education, with faculty utilizing Project Echo at UNM to support these activities

RESEARCH AND SCHOLARLY ACTIVITIES  The ID Division plans to continue and/or initiate basic and translational research activities in the area of Candida albicans pathogenesis, nontuberculous mycobacterial infection, hepatitis C treatment, HIV adolescent medicine, and hospital epidemiology.

CLINICAL OPERATIONS  The Truman Street HIV clinic is transitioning to a new and remodeled facility  A joint pulmonary/ID nontuberculous mycobacteria/bronchiectasis clinic will be started at UNM.  A proposal for a Travel Clinic at UNM through the ID Division and Global Health is being planned for submission

ADMINISTRATION  A new faculty recruitment is in progress for a faculty member to fill the role of UNM Hospital Epidemiologist and Director of the Antimicrobial Stewardship Program.  Administrative support should be to full capacity in the ID Division in the near term

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APPOINTMENTS FACULTY Name Title Effective date Keri Clapper, NP Nurse Practitioner 4/4/2012

STAFF Name Title Effective date Anne Green Administrative Assistant III 9/6/2011

SEPARATIONS FACULTY Name Title Effective date Diane Hanfelt-Goade, M.D. - Retired Professor 6/30/2012 Gregory Mertz, M.D. - Retired Chief 6/30/2012 Katya Calvo, M.D. Visiting Professor 6/30/2012 Vincent Zummo, PA Physician’s Assistant 6/01/2012

STAFF None

PUBLICATIONS OF THE DIVISION AND FACULTY

Thomas Byrd, III, M.D. 1. Davidson LB, Nessar R, Kempaiah P, Perkins DJ, and Byrd TF. 2011. Mycobacterium abscessus glycopeptidolipid prevents respiratory epithelial TLR2 signaling as measured by HβD2 gene expression and IL-8 release. PLoS ONE. 6(12): e29148. doi:10.1371/journal.pone.0029148.

Susan Kellie, M.D. 1. Kellie S, Muller M, Makvandi M. An exposure to varicella in the neonatal intensive care unit: lessons for the vaccine era. American Journal of Infection Control 2011; 39, (10): 844-848.

Nicole Klein, M.D. 1. Hurwitz I, Fieck A, Klein N, Jose C, Kang A, and Durvasula R, “A Paratransgenic Strategy for the Control of Chagas Disease,” Psyche, vol. 2012, Article ID 178930, 10 pages, 2012. Doi:10.1155/2012/178930

Samuel Lee, M.D. 1. Walraven C, Bernardo S, Wiederhold N, Lee SA. Altered biofilm formation in echinocandin-resistant C. albicans mutants. 51st Interscience Conference on Antimicrobial Agents and Chemotherapy. (ICAAC). September 17 – 20, 2011. Chicago, IL. 2. Bernardo SM, Rane H, Lee SA. The Candida albicans t-SNAREs Sso2p and Sec9p are essential for viability and contribute to filamentation. 11th ASM Conference on Candida and Candidiasis. March 29 – April 2, 2012, San Francisco, CA. 3. Harris JR, Lockhart SR, Debess E, Marsden-Haug N, Goldoft M, Wohrle R, Lee SA, Smelser C, Park B, Chiller T. Cryptococcus gattii in the United States: clinical aspects of infection with an emerging pathogen. Clin Infect Dis 2011 Dec;53:1188-95. 4. Chan CY, Prudom C, Raines SM, Charkhzarrin S, Melman SD, De Haro LP, Allen C, Lee SA, Sklar LA, Parra KJ. Inhibitors of V-ATPase proton transport reveal uncoupling functions of tether linking cytosolic and membrane domains of V0 subunit a (Vph1p). J Biol Chem 2012;287:10236-50. 5. Miceli M, Lee SA. Emerging moulds: epidemiologic trends and antifungal resistance. Mycoses 2011 Nov;54:e666-78.

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6. Pincus JL, Jahng M, Massie L, Lee SA. Early Aspergillus pacemaker pocket infection: case and review. Case Rep Med Mycol 2012;1:32–34.

Robert Munk, Ph.D. 1. November 2011: Triant VA, Josephson F, Rochester CG, Althoff KN, Marcus K, Munk R et. al. Adverse Outcome Analyses of Observational Data: Assessing Cardiovascular Risk in HIV Disease. Clin Infect Dis. (2011) doi: 10.1093/cid/cir829

Karla Thornton, M.D., MPH 1. Arora S, Kalishman S, Dion D, Thornton K, Murata G, Fassler C, Jenkusky SM, Parish B, Komaromy M, Pak W, Brown J. “Chapter 3: Knowledge Networks for Treating Complex Diseases in Remote, Rural, and Underserved Communities.” In Learning Trajectories, Innovation and Identity for Professional Development, edited by A. McKee & M. Eraut, pp. 47-70. Vol. 7 of Innovation and Change in Professional Education. New York: Springer, 2012.

Steven Williams, M.D., MPH 1. Gallant JE, Adimora AA, Carmichael JK, Horberg M, Kitahata M, Quinlivan EB, Raper JL, Selwyn P, SB Williams, “Essential Components of Effective HIV Care: A Policy Paper of the HIV Medicine Association, of the Infectious Diseases Society of America and the Ryan White Medical Providers Coalition” Clinical Infectious Diseases 2011; 53(11):1043-50.

OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

Judith Baker, P.A. COMMUNITY OUTREACH  Medical Support Team, Albuquerque International Balloon Fiesta 10/1993-Present

PROFESSIONAL AFFILIATIONS  American Academy of Physician Assistants  New Mexico Academy of Physician Assistants  Ryan White Medical Provider’s Coalition

Thomas Byrd, III, M.D. AD HOC REVIEWER OR EDITORIAL CONSULTANT  Medical Microbiology and Immunology  PLoS One  BMC Infectious Diseases

PROFESSIONAL AFFILIATIONS  American Medical Association

Diane Hanfelt-Goade, M.D. AD HOC REVIEWER OR EDITORIAL CONSULTANT  Journal of Tropical Medicine and Hygiene  Journal of Infectious Diseases  Clinical Infectious Diseases  Antiviral Research  Emerging Infectious Diseases  Journal of Infection in Developing Countries

JOURNAL/EDITORIAL REVIEWER  Journal of Tropical Medicine and Hygiene  Journal of Infectious Diseases

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 Clinical Infectious Diseases  Antiviral Research  Emerging Infectious Diseases  Journal of Infection in Developing Countries

PROFESSIONAL AFFILIATIONS  Western Society for Clinical Investigation  American Society for Virology  American Society for Tropical Medicine and Hygiene  American Society for Microbiology  Infectious Diseases Society of New Mexico  UNM Speakers Bureau  Infectious Diseases Society of America

Michelle Iandiorio, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  Treatment as Prevention. HIV Women’s Perspective Conference. KAETC-Sponsored conference. Kansas City, MO. (1 CME) 3/2/2012.  MRSA SSTI. Presbyterian Hospital Grand Rounds Series. Albuquerque, NM. (1 CME). 2/14/2012.  HIV in the African American Community. African American AIDS Day Conference. Albuquerque, NM. 2/7/2012.  MRSA SSTI. St. Joseph’s Hospital. Dickenson, ND. 11/11/2011.  HIV-HCV Co-Infection. Ft Berthold Reservation. New Town, ND. 11/10/2011.  MRSA SSTI. Trinity Health Hospital. Minot, ND. 11/10/2011.  MRSA SSTI. Sanford Health Hospital. Fargo, ND. 11/9/2011.  HIV Update. University of North Dakota Internal Medicine Residence Program Noon Conference. Fargo, ND. 11/9/2011.  HIV Update. Roswell Department of Health ID Update Conference. Roswell, NM. (1 CME). 10/7/2011.  Standard Precautions. Annual Wound Care Conference. Roswell, NM. (1 CME) 10/7/2011.  MRSA SSTI. Annual Wound Care Conference. Roswell, NM. (1 CME) 10/7/2011.  HIV Local Epidemiology & Testing. Laramie Wyoming Public Health. 9/26/2011.  HIV Local Epidemiology & Testing. Ivinson Memorial Hospital. Laramie, Wyoming. 9/26/2011.  Challenges in Care for HIV-Infected Youth. MPAETC Faculty Development Conference. Denver, CO. (CME- credit). 8/11/2011.

COMMUNITY OUTREACH  Albuquerque AIDS Walk. Fundraising & participation. Albuquerque, NM. 4/28/2012.  Big Sister. Big Brothers Big Sisters. 04/09/2012- present.  HIV 101. Make the Right Decision: Choose You. Minority Youth Girls Conference. Sponsored by the NM State Office of African American Affairs. 03/31/2012.  The Truth About Drugs & Sex. Albuquerque CYFD Independent Living Class. Weekly 90-minute lecture series for foster children aged 15 years and older who will be transitioning out of foster care. CYFD Lamberton Office. Albuquerque, NM. 06/23/2011.  HIV Update. NMAETC-Sponsored Lecture. Los Alamos Regional Hospital. Los Alamos, NM. (1 CME) 06/26/2012.  HIV Post-Exposure Prophylaxis. . NMAETC-Sponsored Lecture. Shiprock, NM. (1 CME) 05/30/2012.  05/04/2012. HIV Treatment in the Transgender Population. New Mexico Transgender Summit. Albuquerque, NM.  HIV Treatment Challenges in Special Populations. NMAETC-Sponsored Lecture. NM DOH Quit Buggin Me Training. Albuquerque, NM. (1 CME) 04/03/2012.  HIV Treatment Challenges in Special Populations. NMAETC-Sponsored Lecture. NM DOH Quit Buggin Me Training. Albuquerque, NM. (1 CME) 03/01/2012.

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 HIV Testing & Treatment Considerations. NMAETC-Sponsored Lecture. UNM Department of Psychiatry Residency Program, First Year Conference. Alb, NM. 12/21/2011.  HIV Treatment Challenges in Special Populations. NMAETC-Sponsored Lecture. NM DOH Quit Buggin Me Training. Albuquerque, NM. (1 CME) 11/17/2011.  HIV Update. NMAETC-Sponsored Lecture. Annual Balloon Fiesta Osteopathic Medicine Update Conference. Albuquerque, NM. (1 CME) 10/06/2011.  Introduction to HIV Resistance. NMAETC-Sponsored Lecture. 17th Annual Four Corners TB & HIV Conference. Santa Fe, NM. (1 CME) 10/04/2011.  HIV-HCV Co-infection. NMAETC-Sponsored Lecture. Gallup IHS Hospital. Gallup, NM. (1 CME) 10/03/2011  HIV 101. NMAETC-Sponsored Lecture. Lea Regional Medical Center. Hobbs, NM. 09/09/2011.  HIV Testing & Local Epidemiology & the Oral Manifestations of HIV. NMAETC-Sponsored Lecture. Southeast NM Dental Hygienist Conference. Hobbs, NM. (1 CME) 09/09/2011.  Perinatal HIV & Reproductive Health in HIV. NMAETC-Sponsored Lecture. Memorial Medical Center. Las Cruces, NM. (1 credit CME) 07/29/2011.  Perinatal HIV & Reproductive Health in HIV. NMAETC-Sponsored Lecture. Roswell, NM. (1 credit CME) 07/28/2011.  HIV Testing Guidelines. Project ECHO Telehealth IAP Clinic. UNM School of Medicine. Albuquerque, NM. 06/03/11.

PROFESSIONAL AFFILIATIONS  New Mexico Annual HIV Update Chair. Albuquerque, NM. 04/26-4/27/2012.  US-Mexico Border AETC Steering Team (UMBAST)  HIV Medical Association (IDSA/HIVMA).  Physicians for a National Health Program (PNHP).  National Infectious Disease Society of America (IDSA; Member #12987).  New Mexico Chapter of the IDSA.

Susan Kellie, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  “Parting shot-getting adult immunization right”, lecture for the joint UNMSOM and Beth Israel/Harvard Medical School CME course, “Update and review of internal medicine 2011”, Santa Fe, New Mexico. 10/21/11  “Clinical update in C. difficile diagnosis, treatment and prevention”, CME talk for providers at Gerald Champion Regional Medical Center, Alamogordo, New Mexico. 12/08/11  “The new C. difficile: diagnosis, treatment and prevention”, talk for medical staff at Plains Regional Medical Center, Clovis, New Mexico. 03/28/12  “Antimicrobial Stewardship: Thinking Globally and Acting Locally”, talk to providers at New Mexico State Behavioral Health facility, Las Vegas, New Mexico 05/02/12

AD HOC REVIEWER OR EDITORIAL CONSULTANT  American Journal of Medicine  American Society for Microbiology journals

COMMUNITY OUTREACH  “Quick-start Antimicrobial Stewardship Curriculum Module 6 : Integrating Antimicrobial Stewardship with Infection Control and Core Measures”, lecture delivered to rural hospitals via Project ECHO 06/07/11  “Quick-start Antimicrobial Stewardship Curriculum Module 7 :Demonstrating the value of your program in an annual report”, lecture delivered to rural hospitals via Project ECHO 06/21/11  “The New Mexico CLABSI Collaborative”, talk at New Mexico Annual Healthcare-Associated Infection Conference sponsored by New Mexico Department of Health, Albuquerque, New Mexico 08/11/11

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 “The New Mexico Clostridium difficile infection prevention project”, talk at New Mexico Annual Healthcare-Associated Infection Conference sponsored by New Mexico Department of Health, Albuquerque, New Mexico 08/11/11  “Matching the infection control program to your setting”, Webex presentation to Indian Health Services personnel, Albuquerque Service Area, IHS.08/23/11  “Hand hygiene and contact precautions in the control of C. difficile”, Webex presentation to New Mexico C.difficile collaborative participants. 08/26/11  “Cleaning the healthcare environment-new perspectives”, Webex presentation to New Mexico C.difficile collaborative participants. 09/22/11  “Introduction to infection control: why it is important to your residents”, Conference call to state nursing home directors, hosted from the New Mexico Medical Review Association. 10/19/11  “C. difficile control in the nursing home setting”, onsite training for long-term care facilities in Santa Fe, New Mexico. 10/21/11  “Hand hygiene in long term care settings-how and why to make it happen”, Conference call to state nursing home directors, hosted from the New Mexico Medical Review Association. 11/02/11  “Overview of the Clostridium difficile infection prevention project in New Mexico” and “Preventing recurrences and readmissions due to C. difficile: using the patient perspective”, talks at New Mexico C. difficile infection prevention project conference, Albuquerque. 11/18/11  “Introduction to infection control: why it is important to your residents”, Talk for state nursing home directors, hosted from the New Mexico Medical Review Association. 11/30/11  “Immunization strategies to improve pregnancy and infant outcomes”, talk for high risk OB ECHO clinic. 12/06/11  “Recognition, management and prevention of methicillin-resistant Staphylococcus aureus infections”, talk to Substance Abuse ECHO clinic. 01/27/2012:  “Catheter-associated UTI: a closer look”, and “Pathfinding through the GU jungle: risk assessment and tools”, talks at Healthcare-Associated Infection Learning and Action Network meeting, Albuquerque. 02/09/12  “CAUTI: first steps”, state-wide conference call to Healthcare-Associated Infection Learning and Action Network, hosted by HealthInsight New Mexico 03/06/12  “Foley-day reduction: low-hanging fruit”, state-wide conference call to Healthcare-Associated Infection Learning and Action Network, hosted by HealthInsight New Mexico 04/03/12  “SIRs, DURs, and using NHSN: CAUTI surveillance update”, state-wide conference call to Healthcare- Associated Infection Learning and Action Network, hosted by HealthInsight New Mexico 05/01/12  “Antimicrobial Stewardship: Thinking Globally and Acting Locally-a Scaleable Approach”, talk for New Mexico Society for Healthcare Pharmacists, given with Carla Walraven, PharmD. 06/23/12  “Update on CAUTI from the national APIC conference”, state-wide conference call to Healthcare- Associated Infection Learning and Action Network, hosted by HealthInsight New Mexico 07/10/12  “Influenza 2012-new choices in immunization”, talk to New Mexico Immunization Coalition, Albuquerque, New Mexico 08/17/12  “Stage 1: the Clostridium difficile infection prevention project”, “Stage 2: the CAUTI collaborative”, “Mountain Stage: Surgical Site Infection”, and “The next stage: why MRSA still matters”, talks at Annual New Mexico Healthcare-associated Infection Conference, sponsored by HealthInsight New Mexico. 08/24/12

PROFESSIONAL AFFILIATIONS  Infectious Diseases Society of America  Society for Healthcare Epidemiology of America  Emerging Infections Network  Association of Professionals in Infection Control and Epidemiology  Infectious Diseases Society of New Mexico  New Mexico Public Health Association

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Nicole Klein, M.D. PROFESSIONAL AFFILIATIONS  American Medical Association  American College of Physicians  Infectious Disease Society of America

Samuel Lee, M.D.  Provided leadership for development of joint UNM/VA antimicrobial stewardship clinical pathways.  Assisted Dr. Michelle Iandiorio (Program Director, UNM ID Fellowship Training Program) with revision of ID fellowship program, including clinical and research training. Will assist Dr. Sarah Allen (incoming Program Director) in this process.  Guided VA ID Section through greatly reduced ID FTE’s (-6/8th, and -3/8th), which will not be replaced due physician hiring freeze at NMVAHCS.  Increased VA ID-HIV clinic, more than doubling the patient census from 79 to 165. This clinic is covered by 0.1 physician FTE’s. Due to VA national reimbursement through VERA dollars, it is estimated that we bring in approx. 1 million/year to NMVAHCS. We have met or exceeded VA national benchmarks in HIV care in every category, except one

INVITED LECTURES: REGIONAL OR NATIONAL  Invited Speaker, “Antifungal Lock Therapy”. 49th Annual Meeting of the Infectious Diseases Society of America, Boston, MA. October 20 – 23, 2011.

AD HOC REVIEWER OR EDITORIAL CONSULTANT  Clinical Infectious Diseases  Fungal Genetics and Biology  Medical Mycology  FEMS Yeast  Research, Mycoses  BMC Bioinformatics  Mycopathologia  Current Genetics  PLoS One  Antimicrobial Agents and Chemotherapy

EDITORIAL BOARD  Member, Peer Review Board, Journal of Visualized Experiments

Gregory Mertz, M.D. EDITORIAL BOARD  Editorial Advisory Board, Journal of Infectious Diseases, 2006-present

GRANT REVIEWER  Member, NIAID Microbiology and Infectious Diseases Research Committee, Bethesda, MD

PROFESSIONAL AFFILIATIONS  NIAID Microbiology and Infectious Diseases Research Committee, Bethesda

Robert Munk, Ph.D. COMMUNITY OUTREACH  New Mexico Governor's Advisory Commission on HIV/AIDS, 2007 - 2011  New Mexico Governor's HIV/AIDS Policy Commission, 2008 - 2011, Commissioner  New Mexico Department of Health Medications Advisory Committee, 1995 – present

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PROFESSIONAL AFFILIATIONS  New Mexico Medical Advisory Board (Deals with AIDS Drug Assistance Program), July 2005 – present  AIDS Treatment Activists Coalition  American Academy of HIV Medicine  European AIDS Treatment Group  Infectious Disease Society of America / HIV Medical Association  International AIDS Society  International Association of Physicians in AIDS Care  National Minority AIDS Council

Elaine Thomas, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  Round Table: Sexual Health, AETC Faculty Development Conference, Denver 8/2011

AD HOC REVIEWER OR EDITORIAL CONSULTANT  Reviewer, Clinical Infectious Diseases  Reviewer, Sexually Transmitted Diseases

PROFESSIONAL AFFILIATIONS  Infectious Disease Society of America and its HIV Medicine Association  Infectious Disease Society of New Mexico  American Sexually Transmitted Diseases Association

Karla Thornton, M.D., MPH INVITED LECTURES: REGIONAL OR NATIONAL  HCV Update on Testing and Treatment. Las Clinicas del Norte, El Rito, NM. 04/2012.  Hepatitis C: The Importance of Testing and Treating. World Hepatitis C Day, Espanola, NM. Sponsor: El Centro Family Health. 07/2011.  HCV Update. HIV Curriculum, Infectious Diseases Fellows, Albuquerque, NM. Sponsor: NM AIDS Education and Training Center.0 2/2012.  Karla Thornton, MD, Sanjeev Arora, MD, Glen Murata, MD. Abstract number 217283. Project ECHO: Outcomes of Hepatitis C Treatment by Primary Care Providers. 18th International Symposium on Hepatitis C Virus and Related Viruses. Seattle, WA. September 8-12, 2011. Oral Presentation.

COMMUNITY OUTREACH  HIV/Hepatitis C Coinfection, Part 1. Truman Street Clinic Curriculum. Albuquerque, NM. Sponsor: NM AIDS Education and Training Center. 09/2012.  HIV/Hepatitis C Coinfection, Part 2. Truman Street Clinic Curriculum. Albuquerque, NM. Sponsor: NM AIDS Education and Training Center. 08/2012.  HCV Update. HIV Curriculum, Infectious Diseases Fellows, Albuquerque, NM. Sponsor: NM AIDS Education and Training Center. 02/2012.

PROFESSIONAL AFFILIATIONS  New Mexico Peer Education Project (NM PEP). Through UNM Project ECHO, started prison peer education project to teach prisoners about Hepatitis C and other infectious disease and teach them how to be educators in the prison system. Developed 40 hour curriculum and conduct trainings quarterly. Currently in 6 prisons throughout New Mexico. Have trained over 150 prisoners who have trained over 1,200 general population inmates. 07/2009 – present.  American Association for the Study of Liver Diseases  National Infectious Disease Society of America (IDSA)  Infectious Diseases Society of New Mexico.

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Steven Williams, M.D., MPH PROFESSIONAL AFFILIATIONS  Member, Steering Committee Ryan White Medical Providers’ Coalition (HIV MA) 2006-Present  Member, HIV QUAL Clinical Advisory Committee NY AIDS Institute, 2006-Present  HIV Medicine Association (IDSA)  International AIDS Society.  Greater Albuquerque Medical Association.  American Academy of Family Practice.  American Medical Association.

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OUTSIDE SPONSORED RESEARCH

Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total NIH/National T cruzi Molecular Targets for 5R01AI066045- Durvasula, Ravi Research 2/1/2011 1/31/2012 0 0 0 Institutes of Health Vector Paratransgenesis 04 Learning and Leadership Hanfelt-Goade, Cystic Fibrosis Colaborative Adult Quality Education HANFEL11QI0 6/1/2011 5/31/2012 1,600 20,000 21,600 Diane E. Foundation Improvement Hanfelt-Goade, Covance, Inc. Clinical Trial Phase II Research BCX1812-201 10/1/2007 9/30/2012 16,225 64,900 81,125 Diane E. Hanfelt-Goade, Quintiles Clinical Trial - Phase 3 Research BCX1812-303 10/15/2009 8/26/2011 22,156 88,625 110,781 Diane E. Laboratories Hanfelt-Goade, Gilead Sciences Clinical Trial Phase III Research GS-US-205-0127 4/20/2010 4/19/2015 13,973 57,394 71,367 Diane E. Mertz, Gregory J. St. Louis University Clinical Trial Research N01-AI-45250 9/1/2006 8/31/2011 58,469 233,874 292,343 Clinical Trial Agreement - Mertz, Gregory J. St. Louis University Research N01-AI-45250 5/30/2008 8/31/2011 452 1,808 2,260 Phase III Mertz, Gregory J. St. Louis University Clinical Trial - Phase 3 Research N01-AI-45250 10/5/2010 8/31/2011 3,120 12,480 15,600 NIH/National Institute of Allergy Andes Virus Transmission and Mertz, Gregory J. Research U01AI045452-12 5/1/2011 4/30/2012 31,532 481,775 513,307 and Infectious Pathogenesis in Chile Diseases NIH/National Institute of Allergy Andes Virus Transmission and U01AI045452-12 Mertz, Gregory J. Research 5/1/2011 4/30/2012 7,203 27,703 34,906 and Infectious Pathogenesis in Chile REVISED Diseases NIH/National Non-Mission HHSN276200900 Munk, Robert AIDS InfoNet NLM 11 9/28/2009 9/27/2011 4,434 55,421 59,855 Library of Medicine Specific 836P NIH/National Non-Mission HHSN276201000 Munk, Robert AIDS InfoNet 2010 9/25/2010 9/24/2011 2,212 27,655 29,867 Library of Medicine Specific 744P HRSA-Health Williams, Steven Resources and Ryan White Part C Outpatient H76HA00130-20- Clinical 1/1/2011 3/31/2012 0 182,860 182,860 Bruce Services EIS Program (bridge funding) 01 Administration HRSA-Health Williams, Steven Resources and Part D HIV Services for WICYF H12HA23021-10- Clinical 8/1/2010 7/31/2011 36,830 296,987 333,817 Bruce Services in Central & NW New Mexico 00 Administration

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Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total HRSA-Health Part D Expansion Grant for Williams, Resources and Medical Case Management H12HA23021-10- Clinical 8/1/2010 7/31/2011 10,316 39,677 49,993 Steven Bruce Services for Women, Children and 01 Administration Youth HRSA-Health Ryan White Part C Williams, Resources and 5H76HA00130- EIS/HIV/AIDS Services for Clinical 1/1/2011 12/31/2011 0 715,408 715,408 Steven Bruce Services 20-00 HMA 1 Administration Williams, Quintiles Clinical Trial Research A4001027 3/28/2009 12/31/2011 0 0 0 Steven Bruce Laboratories Williams, Clinical Clinical Trial - Phase III Research A4001027 8/20/2008 8/19/2013 5,725 22,900 28,625 Steven Bruce Professionals, Inc. Tibotec Williams, TMC278-TiDP6- Pharmaceuticals, Clinical Trial - Phase III Research 8/15/2008 7/31/2012 14,001 55,999 70,000 Steven Bruce C215 Ltd. Salix Williams, Pharmaceuticals, Clinical Trial - Phase III Research NP303-101 1/8/2010 1/7/2015 11,328 45,313 56,641 Steven Bruce Inc.

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NEPHROLOGY

ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Antonia Harford, MD Professor of Medicine Interim Chief, Division of Nephrology

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

EDUCATION  R. Choudhary, T. Ocneanu, C. Reyes, D. Simh and Z. Xu successfully completed their fellowship program.  A. Chadha, D. Chua, D. Mills, and A. Sandhu successfully completed their first year of the fellowship program.  R. George, M. Malik, V. Nair, and A. Regmi entered the nephrology fellowship as first year fellows July 2012.  Nephrology faculty mentor students, residents, and Ph.D. candidates.

RESEARCH AND SCHOLARLY ACTIVITIES  Dr. Philip Zager continues as corporate Medical Director of Quality Management, Dialysis Clinics, Inc., 2006 – present.  Medical Directorship support, Dialysis Clinics, Inc., 1987-present.  Biostatistician support, Dialysis Clinics, Inc., 1987-present.  Eduardo Alas, M.D. continues work on the Evaluation of Cinacalcet HCI Therapy to Lower Cardiovascular Events (EVOLVE) clinical trial.  Ambreen Gul, M.D. continued the Treatment of Periodontal Disease Reduces Cardiovascular Risk (TROPIC) pilot study.  Karen Servilla, M.D. continues as Principal Investigator on the Nephron D VA Cooperative Studies Program, 2008-2013.  Karen Servilla, M.D. serves as a PI on the NIH funded Systolic Blood Pressure Intervention Trial (SPRINT), 2009-2018.  Philip Zager, M. D. continued the Blood Pressure in Dialysis (BID) 9/1/10 – 8/31/13 – National Institutes of Health to study blood pressure in hemodialysis patients. Total award - $1.5 million.  Philip Zager, M.D., continues his work as the Director of the DCI Clinical Research Unit. The focus of this clinical research unit is on outcomes research in ESRD.

CLINICAL OPERATIONS  The division continues to fulfill its clinical obligations at UNMHSC and at DCI facilities throughout NM. From Raton and Taos in the Northern part of the state to Silver City in the South, over 500 End Stage Renal Disease patients throughout the State receive care through these facilities in one of the largest outreach efforts of the UNMHSC.  We continue to perform both deceased donor and living donor renal transplants and have expanded our utilization of pulsatile perfusion for preservation of deceased donor kidneys.  Eduardo Alas, M.D. shares responsibility for the division’s consults and clinical program for both nephrology and transplant. Dr. Alas also shares responsibility for the hemodialysis patients at DCI in Grants  David Buchwald, M.D., shares responsibility for division’s clinical program at UNMHSC. Dr. Buchwald also shares responsibility for medical coverage for the peritoneal dialysis program at DCI-Albuquerque.  James Gibb, M.D. participates in the division’s clinical program at UNMHSC and has responsibility for medical coverage for the hemodialysis patients at DCI in Silver City, Carlsbad and Santo Domingo.  Ambreen Gul, M.D. shares responsibility for the division’s consults and clinical program at UNMHSC.

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 Antonia M. Harford, M.D., is the Medical Director of the UNMH Renal Transplant and the Acute Dialysis Programs and DCI New Mexico. She has responsibility for medical coverage for the hemodialysis patients at DCI in Albuquerque East. During this academic year she has also assumed responsibility for Medical Directorship of UNMHSC’s Dialysis Program. In this capacity, he provides administrative oversight for DCI facilities in NM.  Bruce Horowitz, M.D., shares responsibility for the division’s consults and clinical program at UNMHSC. Dr. Horowitz is responsible for the medical coverage for the hemodialysis patients at DCI in Acoma- Canoncito-Laguna Pueblo.  Mark Rohrscheib, M.D., shares responsibility for the division’s consults and clinical care at UNMHSC and has responsibility for medical coverage for the hemodialysis patients at DCI centers in Taos and Raton.  Helbert Rondon, M.D., shares responsibility for the division’s consults and clinical program at UNMHSC. Dr. Rondon shares responsibility for the nephrology fellowship program.  Karen Servilla, M.D., shares responsibility for the inpatient and outpatient programs at the VAMC. Dr. Servilla also serves as Program Director for the nephrology fellowship program.  Pooja Singh, M.D., shares responsibility for the division’s consults and clinical program for both nephrology and transplant. Dr. Singh has responsibility for the medical coverage for the hemodialysis patients at DCI in Rio Rancho.  Yijuan Sun, M.D. shares responsibility for inpatient and outpatient renal programs at VAMC. She has assumed responsibilities of medical director of the VA dialysis program. Dr. Sun shares responsibility for the hemodialysis patients at DCI Albuquerque.  Philip Zager, M.D. continues his work as the Director of the DCI Clinical Research Unit. The focus of this clinical research unit is on outcomes research in ESRD. Dr Zager also opened new outpatient dialysis facilities in Santo Domingo Pueblo.

COMMUNITY ACTIVITIES  The opening of the Santo Domingo Pueblo Dialysis unit continues the Nephrology Division’s commitment to provide services to New Mexico’s diverse ethnic and racial subpopulations within their own communities.  Ground breaking for latest DCI outreach clinic in Cuba New Mexico occurred April, 2012. This clinic slated for opening in January of 2013 is the result of a strong partnership between the local community leadership and UNMHSC and DCI.  Construction continues on the South Valley DCI unit. This clinic will be uniquely positioned amongst dialysis providers in Albuquerque to offer dialytic services within a community which carries a disproportionate share of kidney disease. This unit will begin offering services on October 1st.

ADMINISTRATION  Antonia Harford, MD assumed the position of Interim Division Chief of Nephrology. Successful recruitment of a permanent division chief was achieved; Mark Unruh from the University of Pittsburgh accepted this Chair position endowed by the Solomon Gardner Sterling Fund.

HONORS AND AWARDS  Philip Zager, MD was a Visiting Professor at the Harvard School of Medicine Division of Nephrology and gave an invited talk on the Zuni Kidney Project at Massachusetts General Hospital and a second lecture at Brigham and Women’s Hospital on the Blood Pressure In Dialysis Study.  DCI endowed the Kidney Research Institute for the study of renal disease (KRI).

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SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

EDUCATION  Require fellow’s participation in research activities that will lend to either publication or a formal presentation at a national or local meeting. Research proposals will be encouraged on problems identified in both basic and clinical investigations including molecular epidemiology, outcomes research, and clinical trials.  Expand renal fellows’ formal education through revamping of renal didactic sessions.

RESEARCH AND SCHOLARLY ACTIVITIES  Expand efforts to identify the genetic and environmental factors that modulate the risk for and the progression of renal disease, diabetes and cardiovascular disease in minority populations in the Southwest.  Develop a transplant database to improve the care and the outcomes of patients with renal disease and hypertension and expand outcomes tracking in transplant patients.  Develop a clinical trials unit to test new therapies for renal disease, hypertension, and renal transplantation.  Expand the research funding within the division. Sources will include the NIH, various foundations, DCI’s Paul Teschan Research Fund, and industry.

CLINICAL OPERATIONS  Expand renal replacement therapy to patients in underserved areas throughout the state of NM.  Plans for a new outpatient dialysis facilities in Cuba, NM as well as the South Valley in Albuquerque, NM.  Develop innovative mechanisms for providing quality renal care in an environment of decreasing resources and increasing demand.  Increase clinical productivity by increasing clinical space. UNMH Medical Specialties clinics do not provide the division with enough clinical rooms to see all our patients in a timely manner, nor for all our fellows to run their continuity clinics. We will continue to actively explore the possibility of moving the division’s office and clinic space to a joint facility with DCI.  Expand pre-ESRD screening and treatment.  Initiate outpatient programs for renal biopsy and treatment of transplant rejection.

ADMINISTRATION  Recruit a director for the Kidney Research Institute (KRI). This individual will work with the newly recruited Division Chief, Dr. Mark Unruh to develop.

APPOINTMENTS

None

SEPARATIONS

None

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PUBLICATIONS OF THE DIVISION AND FACULTY

Eduardo Alas, M.D. 1. Madden K, Tafoya J, Harford A, Alas E, Singh P, Davis MS. Equivalent surgical outcomes in minority renal transplant recipients with and without obesity. Accepted for presentation at the American Congress of Transplantation, June 2012.

James Gibb, M.D. 1. Ashraf U, Weis B, Smalligan RD, Gibb JI, Norton H, Sibbitt WL, Bankhurst A. Outcomes and Cost- Effectiveness of Ultrasound-guided Invasive Procedures Performed by Residents in a Teaching Hospital. Western American Federation for Medical Research Meeting, 2011

Ambreen Gul, M.D. 1. Gul A, Myers OB, Horowitz BL, Bedrick E, Harford A, Zager PG: Similar Mortality in Hemodialysis Patients with Hemoglobin 9 to 9.9 gm/dL versus 10 to 10.9 gm/dL. American Society of Nephrology Kidney Week 2011, 44th Annual Meeting, Philadelpia, PA November 11, 2011

Antonia Harford, M.D. 1. Harford AM, Zager PG. J Am Soc Nephrol.Mortality risk in dialysis patients with naturally higher hemoglobins. 2011 Feb;22(2):205-6. 2. Progression of Risk Factors for Chronic Kidney Disease in Zuni Indians. Harford AM, Shah VO, Ghahate D, Bobelu J, Paine S, Horowitz BL, Cole S, MacCluer J, Laston S, Zager PG. American Society of Nephrology Annual Meeting, 2011 3. Similar Mortality in Hemodialysis Patients with Hemoglobin 9 to 9.9 versus 10 to 10.9. Gul A, Myers OB, Horowitz. B, Bedrick EJ, Harford AM, Zager PG. American Society of Nephrology Annual Meeting, 201

Bruce Horowitz, M.D. 1. Progression of Risk Factors for Chronic Kidney Disease in Zuni Indians. Harford AM, Shah VO, Ghahate D, Bobelu J, Paine S, Horowitz BL, Cole S, MacCluer J, Laston S, Zager PG. American Society of Nephrology Annual Meeting, 2011 2. Similar Mortality in Hemodialysis Patients with Hemoglobin 9 to 9.9 versus 10 to 10.9. Gul A, Myers OB, Horowitz BL, Bedrick EJ, Harford AM, Zager PG. American Society of Nephrology Annual Meeting, 2011 3. A Case of Symptomatic Hyponatremia with DDAVP.(oral presentation) Choudary RK, Horowitz BL. American College of Physicians New Mexico Chapter meeting, 2011. 4. Phosphorus Metabolism. Nephrology Division Noon Conference, 2011. 5. Diabetic Nephropathy, University of New Mexico School of Medicine Renal Block, 2010 and 2011

Darlene Gabaldon, M.D. 1. Gabaldon D, Xu Z, Pett SB, Sun Y, Agaba El, Servilla KS, Murata GH, Tzamaloukas AH. Int Urol Nephrol. Influence of comorbidities and inactivity on the long-term outcomes of coronary artery bypass graft surgery in a small number of men on chronic hemodialysis. 2012 Apr 15. 2. Gabaldon D, Xu Z, Sun Y, Servilla KS, Hartshorne MF, Tzamaloukas AH. Hemodialysis catheter infection with unusual presentation and grave outcome. Hemodial Int. 2011 Oct;15(4):568-72

Mark Rohrscheib, M.D. N/A

Helbert Rondon Berrios, M.D. N/A

Karen Servilla, M.D. N/A

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Pooja Singh, M.D. 1. Goodpasture’s disease complicating human immunodeficiency virus infection. Singh P, Barry M, Tzamaloukas A. Clinical Nephrology. 2011; 76 (1): 74-77.

Yijuan Sun, M.D. 1. Textbook of nephrology 3rd Edition, Dec. 2011. Chapter 28: Technique, Practice, and Complications of Hemodialysis by Servilla KS, Sun Y, and Tzamaloukas AH 2. Gabaldon D, Xhu Z, Pett SB, Sun Y, Agaba EI, Servilla KS, Murata GH, Tzamaloukas AH. Influence of comorbidities and inactivity on the long-term outcomes of coronary artery bypass graft surgery in a small number of men on chronic hemodialysis. Int Urol Nephrol. 2012 Apr 15 3. Gabaldon D, Xu Z, Sun Y, Servilla KS, Hartshorne MF, Tzamaloukas AH. Hemodialysis catheter infection with unusual presentation and grave outcome. Hemodial Int. 2011 Oct;15(4):568-72 4. Kassam H, Sun Y, Adeniyi M, Agaba EI, Martinez M, Servilla KS, Raj DS, Murata GH, Tzamaloukas AH. Hospitalizations before and after initiation of chronic hemodialysis. Hemodial Int. 2011 Jul; 15(3):341-9 5. Sun Y, Kassam H, Adeniyi M, Martinez M, Agaba EI, Onime A, Servilla KS, Raj DS, Murata GH, Tzamaloukas AH. Hospital admissions in elderly patients on chronic hemodialysis. Int Urol Nephrol. 2011 Dec;43(4):1229-36

Philip Zager, M.D. 1. Wilmot B, Voruganti VS, Chang YP, Fu Y, Chen Z, Taylor HA, Wilson JG, Gipson T, Shah VO, Umans JG, Flessner MF, Hitzemann R, Shuldiner AR, Comuzzie AG, McWeeney S, Zager PG, Maccluer JW, Cole SA, Cohen DM. Physiol Genomics.Heritability of serum sodium concentration: evidence for sex- and ethnic- specific effects. 2012 Feb 13;44(3):220-8 2. Igo RP Jr, Iyengar SK, Nicholas SB, Goddard KA, Langefeld CD, Hanson RL, Duggirala R, Divers J, Abboud H, Adler SG, Arar NH, Horvath A, Elston RC, Bowden DW, Guo X, Ipp E, Kao WH, Kimmel PL, Knowler WC, Meoni LA, Molineros J, Nelson RG, Pahl MV, Parekh RS, Rasooly RS, Schelling JR, Shah VO, Smith MW, Winkler CA, Zager PG, Sedor JR, Freedman BI; Family Investigation of Nephropathy and Diabetes Research Group. Am J Nephrol. Genomewide linkage scans for diabetic renal failure and albuminuria: the FIND study. 2011;33(5):381-9. 3. Harford AM, Zager PG. J Am Soc Nephrol.Mortality risk in dialysis patients with naturally higher hemoglobins. 2011 Feb;22(2):205-6.

OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

Eduardo Alas, M.D. PROFESSIONAL AFFILIATIONS  American College of Physicians  Governing Council of the New Mexico ACP Chapter  American Society of Nephrology

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James Gibb, M.D. PROFESSIONAL AFFILIATIONS  American College of Physicians  American Society of Internal Medicine  American Society of Nephrology

Ambreen Gul, M.D. PROFESSIONAL AFFILIATIONS  American Medical Association  American Society of Nephrology  International Society of Nephrology  The Aga Khan University Alumni Association- North American Chapter

INVITED LECTURES: REGIONAL OR NATIONAL  Blood Pressure in Dialysis (BID) Study. Nephrology Noon Conference, November 21, 2011, Division of Nephrology, University of New Mexico, Albuquerque, NM  Magnesium Homeostasis. Nephrology Noon Conference, September 19, 2011, Division of Nephrology, University of New Mexico, Albuquerque, NM  Principles of CKD Management. Nephrology Board Review, August 9, 2011, Division of Nephrology, University of New Mexico, Albuquerque, NM  Ongoing Research at University of New Mexico, Division of Nephrology. Research Day, Nephrology Noon Conference, August 8, 2011, Division of Nephrology, University of New Mexico, Albuquerque, NM.  Treatment of Periodontal Disease Reduces Cardiovascular Risk in Dialysis Patients, NM Health Disparities Research Center (NM CARES HD) Executive Group Meeting, January 7, 2011, University of New Mexico, Albuquerque, NM.

Antonia Harford, M.D. PROFESSIONAL AFFILIATIONS  International Society of Nephrology  American Society of Nephrology  National Kidney Foundation  American Society of Internal Medicine  American College of Physicians  American Federation of Clinical Research  American Society of Transplantation Physicians  American Society of Transplantation

INVITED LECTURES: REGIONAL OR NATIONAL  Madden,K , Tafoya, J, Harford A, Alas E, Singh P, Davis MS Equivalent surgical outcomes in minority renal transplant recipients with and without obesity. Accepted for presentation at the American Congress of Transplantation, June 2012.  Love-Gregory L, Voruganti VS, Laston SL, Haack K, Maccluer JW, Cole SA, Shah VO, Bobelu J, Bobelu A, Ghahate DM, Harford AM, Paine S, Zager P, Comuzzie A, Abumrad NA, Kraja AT. CD36 Polymorphisms Associated with Measures of Renal Disease in Zuni Indians. Presented at American Society of Nephrology, 2011  Gul A, Myers O, Horowitz B, Bedrick E, Harford AM, Zager P. Similar Mortality in Hemodialysis Patients with Hemoglobin 9 to 9.9 Versus 10 to 10.9. Presented at American Society of Nephrology, 2011

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 Voruganti VS, Laston SL, Haack K, Maccluer JW, Cole SA, Shah VO, Bobelu A, Bobelu J, Harford AM, Paine S, Zager P, Comuzzie A. Association of SLC2A9 with Serum Uric Acid and Renal Phenotypes in Zuni Indians. Presented at American Society of Nephrology, 2011  Harford AM, Bobelu A, Shah VO, Ghahate DM, Bobelu J, Paine S, Zager P. Progression of Risk Factors for Chronic Kidney Disease in Zuni Indians. Presented at American Society of Nephrology, 2011

Bruce Horowitz, M.D. PROFESSIONAL AFFILIATIONS  American College of Physicians  American Society of Nephrology  National Kidney Foundation

Mark Rohrscheib, M.D. PROFESSIONAL AFFILIATIONS  International Society of Nephrology  American Society of Nephrology

Helbert Rondon Berrios, M.D. PROFESSIONAL AFFILIATIONS  American Society of Nephrology  International Society of Nephrology  International Society of Peritoneal Dialysis  American College of Physicians  New Mexico Medical Society  Peruvian Society of Nephrology

Karen Servilla, M.D. PROFESSIONAL AFFILIATIONS  American Society of Nephrology  American College of Physicians, Fellow  International Society of Nephrology  American Society of Transplant Physicians

Pooja Singh, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  Madden K, Tafoya J, Harford A, Alas E, Singh P, Davis MS. Equivalent surgical outcomes in minority renal transplant recipients with and without obesity. Accepted for presentation at the American Congress of Transplantation, June 2012.

AD HOC REVIEWER OR EDITORIAL CONSULTANT  Journal of Clinical Nephrology  Established protocols related to patient care for transplant coordinators  Contributor for “Renal Transplant Nursing Self-Study Module  Author/Developer of “Transplant Handbook for UNM Faculty and Fellows”

PROFESSIONAL AFFILIATIONS  American Society of Nephrology  American College of Physicians

Yijuan Sun, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  Sandhu A, Servilla K, Garcia M, Sun Y. Renal Consult Templates and Laboratory Order Sets. Graduate Medical Education QI Conference at University of New Mexico HSC, 2012

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 Xhu Z, Gabaldon D, Sun Y, Servilla KS, Hartshorne MF, Tzamaloukas AH. Lethal hemodialysis catheter infection with misleading symptoms and absence of clinical signs. The 32nd Annual Dialysis Conference, 2011  Xhu Z, Gabaldon D, Pett S, Sun Y, Servilla KS, Murata GH, Tzamaloukas AH. Outcomes of coronary artery bypass surgery in patients on chronic hemodialysis. The 32nd Annual Dialysis Conference, 2011

PROFESSIONAL AFFILIATIONS  2012 - Member in UNMHSC BA/MD Program admission committee  American Society of Nephrology  Fellow of American Society of Nephrology (FASN)

Philip Zager, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  Gul A, Myers O, Horowitz B, Bedrick E, Harford AM, Zager P. Similar Mortality in Hemodialysis Patients with Hemoglobin 9 to 9.9 Versus 10 to 10.9. Presented at American Society of Nephrology, 2011  Voruganti VS, Laston SL, Haack K, Maccluer JW, Cole SA, Shah VO, Bobelu A, Bobelu J, Harford AM, Paine S, Zager P, Comuzzie A. Association of SLC2A9 with Serum Uric Acid and Renal Phenotypes in Zuni Indians. Presented at American Society of Nephrology, 2011  Harford AM, Bobelu A, Shah VO, Ghahate DM, Bobelu J, Paine S, Zager P. Progression of Risk Factors for Chronic Kidney Disease in Zuni Indians. Presented at American Society of Nephrology, 2011  Visiting Professor at the Harvard School of Medicine Division of Nephrology and gave an invited talk on the Zuni Kidney Project at Massachusetts General Hospital and a second lecture at Brigham and Women’s Hospital on the Blood Pressure in Dialysis Study.

JOURNAL/EDITORIAL REVIEWER  Journal American Society of Nephrology  Kidney International  American Journal of Kidney Disease  Clinical Journal of the American Society of Nephrology  Diabetes  Diabetes Care  Journal of Clinical Endocrinology and Metabolism  Metabolism  National Institutes of Health

PROFESSIONAL AFFILIATIONS  American College of Physicians, Fellow  American Society of Nephrology  American Federation for Clinical Research  American Society of Hypertension  European Dialysis and Transplant Association  International Society of Nephrology  Renal Physician Associates  Western Society of Clinical Investigation  Western Society of Clinical Nephrology

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OUTSIDE SPONSORED RESEARCH

Project Faculty Sponsor Name Project Title Sponsor Number Start Stop F A Direct Total type Alas, Eduardo A. Amgen, Inc. Clinical Trial Research 20050182-278 12/15/2009 12/14/2010 3,721 14,885 18,606 Alas, Eduardo A. Amgen, Inc. Clinical Trial Research 20050182-278 12/13/2010 12/31/2011 0 0 0 Bi-Annual Nephrology Gul, Ambreen DaVita Inc. Fellowship Educational Education Gul/DaVita 3/1/2011 2/29/2012 0 5,000 5,000 Grant Relationship between Health Literacy and Horowitz, Bruce Research 11-545 08/11 Chronic Kidney Disease Outcomes Harford, Antonia Dialysis Clinic, Inc. Biostatistician Services Clinical 04-50-A4 9/1/2010 8/31/2011 8,964 68,954 77,918 Cardiovascular Outcomes Singh, Pooja in ethnic minorities post- 06/29/11 transplantation Zager, Philip G. Dialysis Clinic, Inc. Biostatistician Services Clinical PSA-04-50A4 9/1/2009 8/31/2010 8,964 68,954 77,918 DCI Medical Directorship Zager, Philip G. Dialysis Clinic, Inc. Clinical PSA-07-06 2/1/2010 1/31/2011 82,269 632,836 715,105 and QA DCI Medical Directorship Zager, Philip G. Dialysis Clinic, Inc. Clinical PSA-07-06 2/1/2011 1/31/2012 82,269 632,836 715,105 and QA Zuni Utility and Rent Zager, Philip G. Dialysis Clinic, Inc. Clinical 3007858 5/20/2011 7/31/2011 0 2,850 2,850 Support DCI Medical Directorship Zager, Philip G. Dialysis Clinic, Inc. Clinical PSA-07-06 2/1/2010 1/31/2015 31,200 240,000 271,200 and QA NIH/National Institute of Diabetes Genetics of Kidney 3 U01 DK066660- Zager, Philip G. Research 2/1/2010 7/31/2010 0 0 0 and Digestive and Disease in Zuni Indians 04S2 Kidney Diseases NIH/National Blood Pressure in Dialysis Zager, Philip G. Research R01DK083424-01A1 7/15/2010 6/30/2011 57,684 570,170 627,854 Institutes of Health (BID) Pilot Study

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PULMONARY, CRITICAL CARE AND SLEEP MEDICINE ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Richard E. Crowell, MD Professor of Medicine Chief, Division of Pulmonary, Critical Care, and Sleep Medicine

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

 The Division continued the development of Endobronchial Ultrasound procedure. The procedure is now available at both UNM Cancer Center and through the Pulmonary Function Laboratory at UNMH.  Continued progress of the Sepsis Mortality Improvement Team (SMITe), with improvement of the observed sepsis mortality and mortality index in departmental patients (R. Crowell, Chair; M. Boivin, MICU Leader).  In collaboration with the Department of Emergency Medicine, continuation of IHI program “Reducing Sepsis Mortality” to improve recognition and initiation of Early Goal directed Therapy, and facilitate rapid MICU admission in patients with severe sepsis (R. Crowell, Chair; M. Boivin, MICU Leader).  Continued expansion of the Asthma program to Project ECHO, utilizing a novel telemedicine approach to subspecialty care of patients in rural areas of the state and setting up rural asthma education center in Lea County. (M. Harkins).  Maintenance of Divisional billings and collections  In 2011-2012, the division consolidated our specialized regional center of excellence in occupational and environmental lung diseases at the University of New Mexico - the only such clinic in the state. Headed by Akshay Sood, MD, MPH, the clinic serves a catchment area that includes not only New Mexico but also Wyoming, Oklahoma, Texas, Colorado, Arizona, Oregon, Nevada and California. The clinic provides training and education in the field of occupational and environmental lung diseases to postdoctoral fellows and residents in Internal Medicine and Preventive Medicine and provides NIOSH B reader services for rating pneumoconiosis. The clinic also provides unique tertiary-level referral services in the state related to irritant vocal cord dysfunction, maximal cardiopulmonary exercise testing; beryllium lung disease and isocyanate asthma diagnoses and for non-invasive determination of gastroesophageal reflux disease  Continued collaboration with Central New Mexico Community College in Respiratory Therapy training program ( A. Saeed, PI )  Continued development of Research expertise in the areas of: o Basic science and translational research in Lung Cancer biomarkers to guide risk assessment, treatment, and prognostic evaluation o Asthma o Translational research in Critical Care ultrasound  Continued development of Pulmonary Hypertension Program (L. Melendrez-Groves, H. Busby) Dr. Lana Melendrez-Groves completed Pulmonary Hypertension fellowship at Stanford University for FY 2012, to start collaborative program with Cardiology in diagnosis and treatment of patients with Pulmonary Hypertension.

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EDUCATION  Betty Chang, MDCM, PhD continued as Assistant Dean of the Graduate Medical Education program.  Betty Chang, MDCM PhD, continued as Program Director, Internal Medicine  Michelle Harkins, M.D., continues as Director of UNMH-MICU  Michelle Harkins, M.D., Project ECHO Pulmonary Clinic/Grand Rounds: CME presentations: Funded under Robert Wood Johnson Foundation at .25 FTE  Dona J. Upson, M.D., Co-Chair, Workshop on The Pharmacy-Economics of Respiratory Medications, American Thoracic Society International Conference  Continued multiple rotations of House-staff from Internal Medicine, Emergency Medicine, Obstetrics and Gynecology, Anesthesia, Family Medicine, and at UNM (MICU, Pulmonary Consults, and Sleep Center) and the VA (MICU, Pulmonary Consults)  Graduation of Fellows: 1 from the Pulmonary/Critical Care Fellowship, 2 from the Critical Care Fellowship and 2 from the Sleep Fellowship Program  Over 50 presentations by Divisional faculty and trainees at local, regional, and national education and CME sponsored venues.

RESEARCH AND SCHOLARLY ACTIVITIES  11 Externally/internally funded research projects (see “Sponsored Research”).

ADMINISTRATION  Michel Boivin, M.D. was named Assistant Program Director, Critical Care Fellowship  Ali I. Saeed, M.D. was named as Assistant Program Director, Pulmonary and Critical Care Fellowship  Frank Ralls, M.D. was named as Director for the Sleep Medicine Fellowship Program  Betty Chang, M.D. was named Acting Associate Dean for Graduate Medical Education; September 2011

Critical Care Medicine  Continued development and initiation of standardized protocols for the ICU (Iwamoto G, M. Harkins M, Boivin, M)  Ongoing revision of the documentation practices that optimize collections using electronic and progress notes the MICU has converted to electronic provider documentation.

Sleep Medicine  Continued development of a business model for new UNMMG Sleep and Breathing Center.  Continued development of collaborative Sleep Disorder Center with the Albuquerque VA Medical Center.

Veteran’s Administration Hospital (NMVAHCS)  Continued to restructure and expand the PCCM clinical service and research programs at the VA  Restructure the logistics and ancillary support to facilitate outpatient bronchoscopies at the VA.  Restructure outpatient Pulmonary clinics and Pulmonary administrative supporting staff for the section  Established collaborative program with UNM Sleep Disorder Center for care of VA patients with Sleep Disorders.  Ongoing recruitment of faculty members, both physician scientists and clinician educators

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SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

 Continued expansion of EBUS bronchoscopy program (R. Crowell, A. Saeed) to inpatients and OR collaboration with Dr. Jess Schwartz, Thoracic Surgery.  Investigate expansion of bronchoscopic approaches to diagnosis and treatment of pulmonary diseases including electromagnetic guidance and bronchial thermoplasty (A. Saeed).  Continue to nurture referrals to Adult Asthma, Exercise Testing, and Vocal cord Dysfunction programs from UNM and non-UNM patient resources (M. Harkins, A. Sood).  Expand the referral base for and overall clinical operations for Occupational Lung Diseases (A. Sood).  Continued development of ongoing training program in ICU-based ultrasound for faculty and fellows (M. Boivin).  Continued collaborative development of Critical Care Education series for Fellows, Residents, and Students; in collaboration with Departments of Surgery and Neurosurgery.  Development of a process for tracking complications of procedures commonly done in the ICU and on the Pulmonary Consult service

EDUCATION  Continued development of Quality and Safety curriculum for Pulmonary and Critical Care fellows.  Continued to update resident and student rotation curriculum; including development of a standardized online, self-guided curriculum for residents and interns rotating through the MICU (E. Zamora, M.D.)  Improve research opportunities for fellows in training.

RESEARCH AND SCHOLARLY ACTIVITIES  Continue development of research activity in areas of focus, including lung cancer (R. Crowell, J. Mao), asthma (A. Sood, G. Iwamoto, M. Harkins), epithelial leakage during sepsis and critical illness (M. Boivin), heat shock proteins (P. Moseley), and sleep (L. Brown).  Expand research opportunities and oversight for divisional fellow research.  Continue to develop a Global Health Program in respiratory disease (J. Mao).

Critical Care Medicine  Continued development of Critical Care Ultrasound Training Program and Ultrasound education. Dr. Boivin has been invited to teach Ultrasound at Chest 2011.Wesite developed for MICU with reading lists, links to protocols  SEAC grant for critical care web education series for interns (E. Zamora, M. Harkins)  SEAC grant for critical care ultrasound teaching (M. Boivin)

Sleep Medicine  Continued development of expansion plans for expanding the Sleep Disorders Center.  Continue program development with the Albuquerque VA Medical Center  Continued recruitment of additional faculty, and expand research activity.

Veteran’s Administration Hospital (NMVAHCS)  Continue to recruit faculty members and enhance educational opportunities for trainees.  Continue to develop a sleep center at the VA, as a part of an integrated sleep program with UNM  Establish a Global Health Program in respiratory diseases.

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APPOINTMENTS

FACULTY Name Title Effective date Amanda Beck, M.D. Clinical Professor, Volunteer Faculty 1/18/2012

STAFF None

SEPARATIONS

FACULTY Name Title Effective date Amanda Beck, M.D. Professor, Director Sleep Medicine 11/30/2011 Fellowship Program

STAFF None

PUBLICATIONS OF THE DIVISION AND FACULTY

Michel Boivin, M.D. 1. Abouhouli H, Boivin M, Baty G, Assessment of baseline Ultrasound knowledge for placing Central lines. J Invest Med 59:203, 2011 2. Hashimi M, Boivin M, Al-Sadi R, Ma TY. IL-6 Mediation of tight junction permeability through Claudin-2. J Invesig Med 59:153, 2011

Lee K. Brown, M.D. 1. Prevalence of diagnosed sleep apnea among patients with type 2 diabetes in primary care.Heffner JE, Rozenfeld Y, Kai M, Stephens EA, Brown LK.Chest. 2012 Jun;141(6):1414-21. Epub 2011 Nov 17.PMID:22095313[PubMed - in process] 2. Adherence-based coverage of positive airway pressure treatment for sleep apnea: the 'brave new world' of cost-saving strategies.Brown LK.Curr Opin Pulm Med. 2011 Nov;17(6):403-5. No abstract available. PMID:21921794[PubMed - indexed for MEDLINE] 3. Brown LK, Battah S, Wu C, Richards A, Crooks L, Hartshorne M. Response: FDG-PET imaging in the diagnosis of pleural disease [letter]. Chest 2011; 139:967.

H. Katrina Busby, M.D. N/A

Betty Chang, M.D. N/A

Richard Crowell, M.D. 1. Leng S, Bernauer A, Hong C, Do K, Yingling CM, Flores KG, Tessema M, Tellez CS, Willink R, Burki EA, Picchi MA, Stidley CA, Prados MD, Costello J, Gilliland FD, Crowell RE, Belinsky SA. The A/G allele of Rs 16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and lung adenocarcinomas. Clin Cancer Res 17:2014-23, 2011.

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2. Leng S, Bernauer AM, Zhai R, Tellez CS, Su L, Burki EA, Picchi MA, Stidley CA, Crowell, RE, Christiani DC, Belinsky SA. Discovery of common SNPs in the miR-205/200 family-regulated epithelial to mesenchymal transition pathway and their association with risk for non-small cell lung cancer. Int J Mol Epidemiol Genet 2:145-55, 2011. 3. Leng S , Stidley CA, Liu Y, Edlund CK, Willink R, Han Y, Landi MT, Thun MJ, Picchi MA, Bruse SE, Crowell RE, Van Den Berg D, Caporaso NE, Amos CI, Siegfried JM, Tesfaigzi Y, Gilliland FD, SA Belinsky. Genetic Determinants for Promoter Hypermethylation in the Lungs of Smokers: A Candidate Gene-Based Study. Cancer Res 72:707-15, 2012. 4. Samet JM, Crowell RE, Estepar RSJ, Powe NR, Rand, Rizzo AA, Yung R, Lancet E, Chambers J, Rappaport S, Edelman NH. The American Lung Association Interim Report on Lung Cancer Screening. American Lung Association. Guidance on CT Lung Cancer Screening report. http://www.lung.org/lung-disease/lung- cancer/lung-cancer-screening-guidelines/. April 23, 2012.

Karol Dokladny, Ph.D. 1. Thermotolerance and heat acclimation may share a common mechanism in humans.Kuennen M, Gillum T, Dokladny K, Bedrick E, Schneider S, Moseley P.Am J Physiol Regul Integr Comp Physiol. 2011 Aug;301(2):R524-33. Epub 2011 May 25.PMID:21613575[PubMed - indexed for MEDLINE]

Michelle Harkins, M.D. 1. Arora S, Kalishman S, Dion D, Som D, Thornton K, Bankhurst A, Boyle J, Harkins M, Moseley K, Murata G, Komaramy M, Katzman J, Colleran K, Deming P and Yutzy S. Partnering Urban Academic Medical Centers and Rural Primary Care Clinicians to Provide Complex Chronic Disease Care. Health Affairs (Webfirst 5/19/11), 30:6 June 2011. 2. Harkins M, Raissy H, Moseley K, Luttecke K, Arora S. Extension of Community Healthcare Outcomes Project-Asthma Specialty Consultation via Telehealth to Improve Asthma Care in Rural New Mexico.: US Respiratory Disease Vol. 7(1):7-9 September 2011. 3. Yaqub S, Harkins M. A 39 year old female with progressive dyspnea, dry cough and hypoxia: A case report. Southwest J Pulm Crit Care 3:134-40 October 2011.

Oleh Hnatiuk, M.D. 1. Hnatiuk OW. What is the role of PFTs to monitor adverse effects of surgery, drug treatments, and radiation therapy? Respir Care. 2012;57:75-82. 2. Pavletic AJ, Hnatiuk O. Puzzling dyspnea caused by respiratory muscle weakness. J Am Board Fam Med 2012;25:396-7.

Gary Iwamoto, M.D. N/A

Jenny T. Mao, M.D. 1. Body mass index change in adulthood and lung and upper aerodigestive tract cancers.Tarleton HP, Park SL, Zhu WM, Lee YC, Hashibe M, Morgenstern H, Tashkin DP, Mao JT, Cozen W, Mack TM, Zhang ZF.Int J Cancer. 2012 Sep 15;131(6):1407-16. doi: 10.1002/ijc.27383. Epub 2012 Feb 9.PMID:22131048[PubMed - in process] 2. Lung cancer chemoprevention with celecoxib in former smokers. Mao JT, Roth MD, Fishbein MC, Aberle DR, Zhang ZF, Rao JY, Tashkin DP, Goodglick L, Holmes EC, Cameron RB, Dubinett SM, Elashoff R, Szabo E, Elashoff D.Cancer Prev Res (Phila). 2011 Jul;4(7):984-93.PMID:21733822[PubMed - indexed for MEDLINE]

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Lana Melendres-Groves, M.D. N/A

Pope Moseley, M.D. 1. Thermotolerance and heat acclimation may share a common mechanism in humans.Kuennen M, Gillum T, Dokladny K, Bedrick E, Schneider S, Moseley PL. Am J Physiol Regul Integr Comp Physiol. 2011 Aug;301(2):R524-33. Epub 2011 May 25.PMID:21613575[PubMed - indexed for MEDLINE] 2. Effects of whole-body heat acclimation on cell injury and cytokine responses in peripheral blood mononuclear cells.Amorim F, Yamada P, Robergs R, Schneider S, Moseley PL. Eur J Appl Physiol. 2011 Aug;111(8):1609-18. Epub 2010 Dec 30.PMID:21191798[PubMed - indexed for MEDLINE] .

Toru Nyunoya, M.D. 1. Antioxidant diet protects against emphysema, but increases mortality in cigarette smoke-exposed mice. Nyunoya T, March TH, Tesfaigzi Y, Seagrave J.COPD. 2011 Oct; 8(5):362-8. Epub 2011 Aug 11.PMID:21834692[PubMed - indexed for MEDLINE]

Frank Ralls, M.D. 1. J of Clinical Neurophysiology 4/2011 Primary Sleep Disorders and Paroxysmal Nocturnal Non-Epilpetic Events in Adults with Epilepsy. Grigg-Damberger, Madeline M.D., Ralls, Frank M.D. 2. Clinical Neurology of Aging, 3rd Edition 2011 Sleep Disorders in Aging. Beck, A, Ralls, F 3. American Parkinson Disease Association (APDA) Newsletter Fall 2011 “Your Sleep-Your Life” Ralls, F

Ali Saeed, M.D. 1. Delayed presentation: negative pressure pulmonary hemorrhage. Saeed AI, Quintana C, McGuire FR, Barker JA.J Clin Anesth. 2012 May 22. [Epub ahead of print]PMID:22626686[PubMed - as supplied by publisher] 2. Role of nicotinic receptors and acetylcholine in mucous cell metaplasia, hyperplasia, and airway mucus formation in vitro and in vivo.Gundavarapu S, Wilder JA, Mishra NC, Rir-Sima-Ah J, Langley RJ, Singh SP, Saeed AI, Jaramillo RJ, Gott KM, Peña-Philippides JC, Harrod KS, McIntosh JM, Buch S, Sopori ML.J Allergy Clin Immunol. 2012 May 9. [Epub ahead of print]PMID:22578901[PubMed - as supplied by publisher] 3. Acute lung injury induced by Staphylococcal enterotoxin B: disruption of terminal vessels as a mechanism of induction of vascular leak. Saeed AI, Rieder SA, Price RL, Barker J, Nagarkatti P, Nagarkatti M.Microsc Microanal. 2012 Jun;18(3):445-52. Epub 2012 May 10.PMID:22571856[PubMed - in process]

Akshay Sood, M.D., MPH 1. Function In Smokers, Am J Respir Crit Care Med 185;2012:A2266 2. Meek, P; Sood, A; Petersen, H; Tesfaigzi, Y.Symptoms Of Smokers Exposed To Wood Smoke: Are There Differences? Am J Respir Crit Care Med 185;2012:A2587 3. Meek, P; Sood, A; Petersen, H; Tesfaigzi, Y.Symptoms Of Smokers Exposed To Wood Smoke: Are There Differences? Am J Respir Crit Care Med 185;2012:A2587 4. Tang, W., Joubert, BR, Artigas, MS, Dupuis, J, Kowgier, M, Foy, M, Marciante, KD, Gharib, SA, Palmer, LJ, Sood, A, Strachan, DP, London, SJ, O’Connor, GT, Tobin, M, Cassano, PA. Meta-analysis of Genome-Wide Association Studies of Longitudinal Decline in Lung Function. Am J Respir Crit Care Med 185;2012:A3807 5. Kelly, E; Tesfaigzi, Y; Petersen, H; Sood, A; Nakajima, T; Martin, S; Divo, M; Washko, G; Pinto-Plata, VM; Owen, CA; Celli, BR. Biomarker Profile In Smokers Without Chronic Obstructive Pulmonary Disease (COPD) Who Are FEV1 Decliners Versus Non Decliners, Am J Respir Crit Care Med 185;2012:A4508

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6. Assad, NA; Qualls, C; Smith, LJ; Arynchyn, A; Thyagarajan, B; Jacobs, D; Sood, A. BMI-defined obesity is a stronger predictor than metabolic syndrome for future asthma risk in women - the longitudinal CARDIA study. Am J Respir Crit Care Med 185;2012:A6499. 7. Sood, A; Seagrave, J; Herbert, G; Harkins, M; Qualls, C; Schuyler, M. Asthma Is Associated With Lower Adiponectin Concentrations in Sputum than Controls. Am J Respir Crit Care Med 185;2012:A6502 8. Zhu, N; Jacobs, DR; Sidney, S; Sternfeld, B; Carnethon, M; Lewis, CE; Shay, CM; Sood, A; Bouchard, C. Fat mass modifies the association of fat-free mass with symptom-limited treadmill duration in the Coronary Artery Risk Development in Young Adults study. Am J Clin Nutr. Am J Clin Nutr. 2011 Aug; 94(2):385-91. 9. Artigas, MS; Loth, DW; Wain, LV; Gharib, SA; Obeidat, M; Tang, W; Zhai, G; Zhao, JH; Smith, AV; Huffman, JE; Albrecht, E; Jackson, CM; Evans, DM; Cadby, G; Fornage, M; Manichaikul, A; Lopez, LM; Johnson, T; Aldrich, MC; Aspelund, T; Barroso, I; Campbell, H; Cassano, PA; Couper, DJ; Eiriksdottir, G; Franceschini, N; Garcia, M; Gieger, C; Gislason, KJ; Grkovic, I; Hammond, CJ; Hancock, DB; Harris, TB; Ramasamy, A; Heckbert, SR; Heliövaara, M; Homuth, G; Hysi, PG: James, AL; Jankovic, S; Joubert, BR; Karrasch, S; Klopp, N; Koch, B; Kritchevsky, SB; Launer, LJ; Liu, Y; Loehr, LR; Lohman, K; Loos, RJF; Lumley, T; Balushi AKA; Ang, WQ; Barr, RG; Beilby, J; Blakey, JD; Boban, M; Boraska, V; Brisman, J; Britton, JR; Brusselle, GG; Cooper, C; Curjuric, I; Dahgam, S; Deary, IJ; Ebrahim, S; Eijgelsheim, M; Francks, C; Gaysina, D; Granell, R; Gu, X; Hankinson, JL; Hardy, R; Harris, SE; Henderson, J; Henry, A; Hingorani, AD; Hofman, A; Holt, PG; Hui, J; Hunter, ML; Imboden, M; Jameson, KA; Kerr, SM; Kolcic, I; Kronenberg, F; Liu, JZ; Marchini, J; McKeever, T; Morris, AD; Olin, A; Porteous, D; Postma, DS; Rich, SS; Ring, SM; Rivadeneira, F; Rochat, T; Sayer, AA; Sayers, I; Sly, PD; Smith, GD; Sood, A; Starr, JM; Uitterlinden, AG; Vonk, JM; Wannamethee, SG; Whincup, PH; Wijmenga, C; Williams, OD; Wong, A; Mangino, M; Marciante, KD; McArdle, WL; Meibohm, B; Morrison, AC; North, KE; Omenaas, E; Palmer, LJ; Pietiläinen, KH; Pin, I; Polašek, O; Pouta, A; Psaty, BM; Hartikainen, A; Rantanen, T; Ripatti, S; Rotter, JI; Rudan, I; Rudnicka, AR; Schulz, H; Shin, S; Spector, TD; Surakka, I; Vitart, V; Völzke, H; Wareham, NJ; Warrington, NM; Wichmann, H; Wild, SH; Wilk, JB; Wjst, M; Wright, AF; Zgaga, L; Zemunik, T; Pennell, CE; Nyberg, F; Kuh, D; Holloway, JW; Boezen, JH; Lawlor, DA; Morris, RW; Probst-Hensch, N; The International Lung Cancer Consortium, GIANT consortium, Kaprio, J; Wilson, JF; Hayward, C; Kähönen, M; Heinrich, J; Musk, AW; Jarvis, DL; Gläser, S; Järvelin, M; Stricker, BHC; Elliott, P; O'Connor, GT; Strachan, DP; London, SJ; Hall, IP; Gudnason, V; Tobin, MD. Genome-wide Association and Large Scale Follow-up Identifies 16 New Loci Influencing Lung Function. Nat. Genet. 2011 Sep 25; 43(11):1082-90. doi: 10.1038/ng.941 10. Bruse, S; Sood, A; Petersen, H; Liu, Y; Leng, S; Celedon, JC; Gilliland, F; Celli, B; Belinsky, SA; Tesfaigzi, Y. New Mexican Hispanic smokers have lower odds of chronic obstructive pulmonary disease and less decline in lung function than non-Hispanic whites. Am J Resp Crit Care Med; 2011 Dec 1;184(11):1254-60 11. Sood, A; Dominic, E; Qualls, C; Steffes, M.W.; Thyagarajan, B; Smith, L.J.; Lewis, CE; Jacobs, D.R. Serum Adiponectin is Associated with Adverse Clinical Control and Severity of Asthma in Men but not in Women. Front. Pharmacol. 2011;2:55. 12. Sood, A; Petersen, H; Blanchette, C.M; Meek, P; Picchi, M.A.; Belinsky, S.A.; Tesfaigzi, Y; Methylated Genes in Sputum among Older Smokers with Asthma. Chest 2012 Feb 16 13. Sood, A; Qualls, B; Thyagarajan, M; Steffes, M; Smith, LJ; Jacobs, DR. Low Serum adiponectin predicts future risk of asthma in women. Am J Resp Crit Care Med. 2012 Apr 6. [

Dona Upson, M.D. N/A

Eleana Zamora, M.D. N/A

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OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

Michel Boivin, M.D.  American Federation of Medical Research – Councilor for New Mexico 2005-present  Tri-Societies Western Meeting Planning Committee 2006-present  Lead Reviewer Pulmonary Section (Carmel Meeting) 2007-present  AFMR – Western Section – Past-Chair 2010-2011  ACCP Governor for New Mexico 2011-  Phase I Tutorial Co-leader GI / Nutrition Block September – October 2011

JOURNAL/EDITORIAL REVIEWER  Journal of Investigative Medicine 2007-present  Nutrition Research 2007-present  Experimental Biology and Medicine 2008-present  American Journal of Physiology 2008-present

Lee K. Brown, M.D. New Mexico Thoracic Society President 2010 - present Planning Committee, 29th - 36th Annual New Mexico Thoracic Society Lung Disease Symposia American College of Chest Physicians Sleep Institute Organizational Framework Task Force (2009 – present) Steering Committee, Sleep Medicine Clinical NetWork (Ex Officio, 2006-present Sleep Issues in Healthcare Workers Task Force (2008 – present) American Academy of Sleep Medicine In-service Examination Task Force (2010 – present) Ad Hoc NPPV Titration Protocol Task Force (2008 – present) Associate Editor, Journal of Clinical Sleep Medicine (2006-present) Book Review Editor, Journal of Clinical Sleep Medicine (2006-present) Greater Albuquerque Medical Association Member-at-large, Board of Trustees (2010 – present) Recruitment and Retention Committee (2009 – present) Ad Hoc Committee on Recruitment and Retention (2009 – present) New Mexico Medical Society Liaison Committee to the UNM School of Medicine (2001-present) State of New Mexico Polysomnography Practice Advisory Committee of the New Mexico Medical Board (2008-present; Chair, 2009-present) Respiratory Care Advisory Board (2010 – present)

H. Katrina Busby, M.D.

INVITED LECTURES: REGIONAL OR NATIONAL  February 2012: New Mexico ATS Meeting: Pulmonary Hypertension

PROFESSIONAL AFFILIATIONS  Member, CV pulm block committee, 2010-present  Member. GME operations committee, 2005-present

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 Attending Physician Veterans Administration Medical Intensive Care Unit  Staff Physician, Veterans Administration Pulmonary Clinic

Betty Chang, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  June 2011, Duty Hours and the Sleep Data that Supports Limits, UNM Internal Medicine Grand Rounds.

JOURNAL/EDITORIAL REVIEWER  Abstract Reviewer ACP Annual Meeting, 2010, 2011  Abstract Judge ACP Annual Meeting, 2010, 2011  Reviewer for Journal of Rheumatology 2006 to present  Reviewer for Arthritis and Rheumatism 2004 to present  Reviewer for Chest Journal 2004 to present

PROFESSIONAL AFFILIATIONS  Fellow, American College of Chest Physicians (1999 – present)  American Thoracic Society (1999 – present)  American College of Physicians (1996 – 2000; 2008-present)  Association of Program Directors of Internal Medicine (2007 – present)  ACP Medical Student Mentoring Discussant, 2010, 2011

Richard Crowell, M.D.  American College of Chest Physicians.  Member, Thoracic Oncology Network  American Thoracic Society.  Member, Clinical Problems Assembly  International Association for the Study of Lung Cancer  American Association for Cancer Research  American Lung Association, New Mexico Chapter  Member, Board of Directors

Karol Dokladny, Ph.D. N/A

Michelle Harkins, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  Harkins M, Raissy HH, Moseley K, Luttecke K, Arora S. Project ECHO: Improving Asthma Care in New Mexico with Telehealth Technology. ACCP, October 2011, Hawaii  Harkins M, Raissy HH, Moseley K, Luttecke K, Arora S. Engaging the School Nurse as part of the treatment team via telehealth improves asthma care. ATS, May 2012, San Francisco  2011 Asthma Update: Obtaining optimal patient control, June, NM Regional Pharmacy Association, Albuquerque  2011 Asthma Update and Ventilator management, ACP regional meeting, October  2012 Asthma Exacerbation, Winterfest NM RT conference January, Ruidoso  2012 All that Wheezes isn’t asthma, NM Thoracic Society Meeting, ABQ, February  2012 Hantavirus: A Tale of Mice and Men; the UNM experience, ATS International conference, San Francisco, Sunrise Seminar

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Oleh Hnatiuk, M.D. N/A

Gary Iwamoto, M.D. JOURNAL/EDITORIAL REVIEWER  Reviewer for Journal of Applied Physiology  Reviewer for American Journal of Respiratory Cell and Molecular Biology  Reviewer for Biochim Biophys Acta  Reviewer for American Review of Respiratory Disease

PROFESSIONAL AFFILIATIONS  American College of Physicians  Present American College of Chest Physicians  American Thoracic Society  American Federation of Clinical Research

Jenny T. Mao, M.D.  Member, Institutional Biosafety Committee. NMVAHCS  Member, PCCM Fellow Research Review Committee. UNM  Member, Center for Cellular and Molecular Biology Research, MVAHCS  Member, NMVAHCS Cancer committee.  Member, Critical Care Committee, NMVAHCS  Member, Infection Control Committee, NMVAHCS.

Lana Melendres-Groves, M.D.  Member, American Thoracic Society  Member, American College of Chest Physicians

Pope Moseley, M.D. JOURNAL/EDITORIAL REVIEWER  A review of sex differences in immune function after aerobic exercise.Gillum TL, Kuennen MR, Schneider S, Moseley P.Exerc Immunol Rev. 2011;17:104-21. Review. PMID:21446354[PubMed - indexed for MEDLINE]

PROFESSIONAL AFFILIATIONS  American Thoracic Society  American College of Chest Physicians, Fellow  American College of Sports Medicine, Fellow  American College of Occupational Medicine  American Physiological Society  American College of Forensic Examiners

Toru Nyunoya, M.D.  2011 CTSC Innovation Award  2010-12 Midwest Affiliate AHA Grant-in-aid Award  2010-12 NIH R03 Award

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Frank Ralls, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  July 15, 2011: New Mexico Academy of Family Physicians 54th Family Medicine Seminar, Ruidoso, NM, Sleep Disorders in Primary Care: Pediatric and Adult Obstructive Sleep Apnea  September 25, 2011 New Mexico Chapter of Parkinson’s Disease. Taos, NM. Lecture: Sleep and The PD Patient.  September 27, 2011 GME Operations Committee. Resident Fatigue and Attending Responsibilities  October 19, 2011 ENT Faculty and Residents. Understanding Pediatric Sleep Apnea  October 20, 2011 Pediatric Nephrology: Understanding Resident Fatigue  January 19, 2012 ECHO Lecture: Opiates, Sleep, and Breathing  January 20, 2012 Ground Rounds in Psychiatry: Fatigue and Sleep Deprivation  January 26, 2012 ECHO Lecture: Pain and Sleep in Elders  April 14, 2012 American Association of Parkinson’s Disease, New Mexico Chapter of Parkinson’s Disease Symposium: Lecture: Abnormal Movements in Sleep

PROFESSIONAL AFFILIATIONS  Member, American Academy of Sleep Medicine 2008-Present  Member, American Academy of Hospice and Palliative Care 2010-Present  Member, American Academy of Geriatrics 2008-Present  Member, Greater Albuquerque Medical Society 2010-Present

Ali Saeed, M.D.  CNM Respiratory Therapy Program, Associate Director  Pulmonary and Critical Care (combined) Fellowship Training Assistant Program Director  Member, American College of Chest Physicians (ACCP)  Member, Pakistan Medical and Dental Council (PMDC)

Akshay Sood, M.D., MPH JOURNAL/EDITORIAL REVIEWER  Assad, N. Sood, A. Leptin, Adiponectin and Pulmonary Diseases. Biochimie. 2012 Mar 14.

PROFESSIONAL AFFILIATIONS  Member, American Thoracic Society  Member, American Thoracic Society, Environment and Occupational Health Assembly  Fellow, American College of Chest Physicians  Member, American College of Occupational and Environmental Medicine  Member, International Program Committee, Environment and Occupational Health Assembly, American Thoracic Society May 2011-May 2014

Dona Upson, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  Invited by Sen. Tom Udall, as a expert panelist, U.S. Senate Committee on Environment and Public Works, Subcommittee on Clean Air and Nuclear Safety and the Subcommittee on Children’s Health and Environmental Responsibility at a hearing entitled “Air Quality and Children’s Health.” 2011  Invited participant, National ALA’s Lung Health Disparities Roundtable, Washington DC. 2011  Great Cases Symposium: Clinical, Radiologic and Pathologic Correlations by Master Physicians, 2011. ATS International Conference

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 Tobacco Use Prevention and Cessation Program: A Continuing Education Program for Healthcare Practitioners in New Mexico, 4th Edition 2011

PROFESSIONAL AFFILIATIONS  American Thoracic Society (ATS, National) Board of Directors, 2010- Chair, Council of Chapter Representatives (CCR), 2011-12 Chair-elect, Council of Chapter Representatives (CCR), 2010-11

Eleana Zamora, M.D. INVITED LECTURES: REGIONAL OR NATIONAL  June 2011: “Antibiotic Stewardship” Presbyterian Healthcare Systems  September 2011: “The XYZs of Common Infections” Internal Medicine Resident lecture series, University of New Mexico School of Medicine  October 2011: “Basics of Mechanical Ventilation” Internal Medicine Resident lecture series, University of New Mexico School of Medicine

PROFESSIONAL AFFILIATIONS  American College of Chest Physicians  Board Member, NM Chapter of Society of Critical Care Medicine  Infectious Disease Society of America, Member  American College of Physicians, Member

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OUTSIDE SPONSORED RESEARCH

Associated Sponsor Faculty Sponsor Name Project Title Project type Start Stop F A Direct Total Department* Number Sood, Akshay Clinical And Lovelace Biomarker Signature Research JK112532 01- 31-May- 51% $11,222.00 $16,931.00 Translational Biomedical & in COPD Jun- 2012 Science Environmental 2011 Center CTSC Research Institute Sood, Akshay Clinical And NIH/National Obesity-related Host Research 5K23HL09453 01- 31-Jul- 8% $163,931.00 $177,045.00 Translational Heart, Lung, and Susceptibility Factors 1-03 Aug- 2012 Science Blood Institute in Asthma in Women 2011 Center CTSC Crowell, Richard Internal United Pulmonary Fellowship Other Crowell/UTC/ 16- 17-May- 0% $7,500.00 $7,500.00 Medicine IM Therapeutics support Fellowship Nov- 2011 Corporation 2010 Crowell, Richard Internal Specialty Program Director Clinical PSA-09-46 01- 31-Jan- 0% $127,500.00 $127,500.00 Medicine IM Hospital of Services for the Jan- 2012 Albuquerque Pulmonary Care Unit 2011 Crowell, Richard Internal Lovelace Factors for Epigenetic Research JK102040 01- 31-May- 26% $45,000.00 $56,700.00 Medicine IM Biomedical & Silencing of Lung Jun- 2012 Environmental Cancer Genes 2011 Research Institute Hanfelt-Goade, Internal Cystic Fibrosis Cystic Fibrosis Care Research C073-11AD 01-Jul- 30-Jun- 0% $31,820.00 $31,820.00 Diane Medicine IM Foundation Center - Adult 2011 2012 Hanfelt-Goade, Internal Cystic Fibrosis Learning and Education HANFEL11QI0 01- 31-May- 8% $20,000.00 $21,600.00 Diane Medicine IM Foundation Leadership Jun- 2012 Colaborative Adult 2011 Quality Improvement Klepper, Diane Internal Central New Participation in the Research BO305305 01- 31-Aug- 16% $41,268.00 $47,871.00 Medicine IM Mexico Respiratory Therapy Sep- 2012 Community Educational Program 2011 College *Proposal Primary

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Associated Sponsor Faculty Sponsor Name Project Title Project type Start Stop F A Direct Total Department* Number Moseley, Pope Internal Zenith Outpatient Other PSA-08-49 21- 31-Jul- 0% $25,000.00 $25,000.00 Medicine IM Administrators Professional Services Aug- 2012 2011

Moseley, Pope Internal Dialysis Clinic, Professional Services Other PSA-07-06A1 01- 31-Jan- 0% $800,000.00 $800,000.00 Medicine IM Inc. Agreement - Medical Feb- 2012 Director 2011

Sood, Akshay Office of American Lung Adiponectin and Research CK1130/SOO 01- 31-Aug- 0% $100,000.00 $100,000.00 Research Thoracic Society Asthma in Women D/14822 Sep- 2012 2010 *Proposal Primary

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CENTERS AND PROJECTS

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ALLERGY SERVICE ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Mark Schuyler, MD Professor of Medicine Chief, Allergy Service

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

EDUCATION Tutor in the Phase I Immunity Block in the Medical School Curriculum.

RESEARCH AND SCHOLARLY ACTIVITIES  Continued mentoring of Akshay Sood.  Chair of the CTSC KL2 MAC.

CLINICAL OPERATIONS  Continuation of an Allergy Clinic on the West Side. During the past year, 52% of patients were non- UNM/UNMH (i.e. successful outreach to non-UNM patients).

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

I will continue efforts to change the Westside Allergy clinic from a Hospital to a Medical Group clinic.

EDUCATION I will continue to participate in Phase I Medical School tutoring, attend Morning report and other activities as requested.

RESEARCH AND SCHOLARLY ACTIVITIES I will continue to mentor Akshay and others as requested. I will also continue as KL2 Chair that involves assisting UNM HSC junior faculty in their research careers.

CLINICAL OPERATIONS  Allergy will continue its clinical services at the Westside clinic and provide Allergy services for inpatients and outpatients at UNMH.

ADMINISTRATION  MAC Chair (part of UNM CTSC)  Managed Allergy Services at UNMH.

APPOINTMENTS AND SEPARATIONS OF FACULTY AND STAFF

None.

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PUBLICATIONS OF THE DIVISION AND FACULTY

Mark Schuyler, MD 1. Sood A, Qualls C, Li R, Schuyler M, Beckett W, Smith, L, Thyagarajan B, Lewis C, Jacobs, D. Lean mass predicts asthma better than fat mass among females. Eur Respiratory J 37:65-71, 2011. 2. Mebratu Y, Schwalm K, Smith K, Schuyler M, Tesfaigzi Y. Cigarette smoke suppresses Bik to cause epithelial hyperplasia and mucous cell metaplasia. Am J Resp Crit Care Med 183: 1531-38, 2011.

OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

Mark Schuyler, MD PROFESSIONAL AFFILIATIONS  Member, American Thoracic Society, American Academy of Allergy and Immunology, American College of Chest Physicians.

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OUTSIDE SPONSORED RESEARCH

Project Faculty Sponsor Name Project Title Sponsor Number Start Stop F A Direct Total type Schuyler, KL2 Director 4/1/11 present Mark UNM CTSA Obesity-related Host NIH/National Institutes Sood, Akshay Susceptibility Factors in Research K23HL094531-01A1 9/15/2009 9/14/2013 13,442 168,027 181,469 of Health Asthma in Women American Thoracic Lung Adiponectin and Sood, Akshay Research CK1130/SOOD/14822 9/1/2010 8/31/2012 0 100,000 100,000 Society Asthma in Women

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CENTER FOR GLOBAL HEALTH ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Douglas J. Perkins, PhD Professor of Medicine Director, Center for Global Health

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

Since its inception on July 1, 2010, the UNM Center for Global Health (CGH) has formed an interdisciplinary group of scientists to meet the educational and research goals of UNM. This includes forming bilateral exchange with our educational and research partners around the globe.

Towards this end, critical components of this approach include training future generations of global health researchers; integration of activities between centers in the US and the developing world; and engagement of community stakeholders who are not formally part of the academic enterprise.

 We have also developed two new global health courses as part of the interdisciplinary graduate program at UNM that we teach each year.  In addition, we formed a Global Health Certificate Program in partnership with the Biomedical Sciences Graduate Program in the Health Sciences Center.  The courses and Certificate Program create a unified educational experience, with well-defined didactic course work, and practical experience in a global health setting for UNM and international partner trainees.  We are currently developing a national and internationally funded research portfolio that bridges UNM activities with 13 partner medical centers in Asia, Africa, Mexico, and Central and South America.  Another significant achievement was the development of a fourth year tropical medicine clerkship for UNM medical students at our clinical training sites around globe.  The CGH has offered research internships for graduate and medical students, postdoctoral fellows, and faculty.  We have also developed a Global Health Residency track for Internal Medicine Residents that have traveled to Ecuador, India, and Kenya.

EDUCATION Douglas J. Perkins  Mentored five junior faculty, four postdoctoral fellows, one ID fellow, four PhD students, two medical students, seven MSc students, and two undergraduates.

RESEARCH AND SCHOLARLY ACTIVITIES  “UNM Framework Program for Global Health” NIH/Fogarty, R25TW008099, 05/06/09-06/30/12, $405,000 (DJ Perkins, PI).  “Genetic Basis of Severe Malarial Anemia” NIH, R01 AI051305-06, 04/01/07-03/31/13, $2,303,030 (DJ Perkins, PI).  “Training and Research on Severe Malarial Anemia, NIH, Fogarty International Center, D43 TW005884-06, 08/02/07-03/31/13, $746,015 (DJ Perkins, PI).

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 “Ecology of African Highlands Malaria”, NIH, sub-award with UC-Irvine, 2 R01 AI50243, 05/01/08- 02/28/12, $290,564, G Yan, PI, UC-Irvine (DJ Perkins, PI, UNM sub-award).  “Molecular immunologic role of cytokines in the development of malarial immunity”, NIH/Fogarty, R01 TW007631-02 A1 08/01/07-07/31/11, $200,000 JM Ong’echa PI, (DJ Perkins, Co-I/mentor).  “Impact of Surface Receptors and FC Gamma Receptors in Severe Malarial Anemia”, NIH/GRIP, 1 R01 TW008306-01, 09/20/2009-09/20/2012, $200,000 C Ouma PI (DJ Perkins, Co-I/mentor).  “University of New Mexico Preventive Medicine Residency Program”, HRSA, 07/01/10-06/30/14, $343,643 D Kesler (DJ Perkins, Co-Investigator).  “Randomized clinical trial of childhood antimalarials”, WHO, 09/01/09-10/31/12, $80,000 B Ogutu, PI (DJ Perkins, Co-Investigator).  Department of Defense Strategic Engagement Partner.

COMMUNITY ACTIVITIES Douglas J. Perkins  Founder and Director, Siaya District Community Sickle Cell Anemia Foundation.  Board Member, Ogra Foundation, Kisumu, Kenya  Director, University of New Mexico International Malaria Training and Research Program (IMRTP)  Member, University of New Mexico Clinical and Translational Science Center (CTSC), Participant and Clinical Interactions Resources (PCIR) Committee

ADMINISTRATION Douglas J. Perkins  Established and Directed the Center for Global Health (1 July 2010)  Co-Director, Center for Infectious Diseases and Inflammation, Health Sciences Center  Travelled to Kenya to Direct NIH activities  Director of University of New Mexico International Malaria Training and Research Program (UNMIMTRP)  Member of University of New Mexico, Department of Internal Medicine, Promotion and Tenure Committee  Member, Executive Committee, Division of Infectious Diseases  Member, Executive Committee, Department of Internal Medicine

Ravi Durvasula, Associate Director  Established and Co-Directed the Center for Global Health (1 July 2010)  Member, Executive Committee, Department of Internal Medicine  Member, Academic Affiliation Partnership Council  Development of a new clinical residency program within the Center for Global Health  Recruitment of new faculty to the Center

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

EDUCATION  A leading goal for the CGH is to offer students and faculty at UNM high quality educational programs. This will include an integrated approach to education that supports a multicultural and multidisciplinary environment. Through our educational programs, we strive to promote excellence in research, education,

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and expand our activities to include clinical training and services in global health. This will allow us to train future generations of global health researchers and practitioners. In addition, through events such as our Global Health Symposium, we will engage community stakeholders who may not formally be a part of the academic enterprise. The Center’s goal is to continue to provide educational opportunities in tropical medicine for graduate and medical students, residents, and post-doctoral fellows.  Continue development of the Global Health Certificate Program

RESEARCH AND SCHOLARLY ACTIVITIES  The CGH was formed to support and enhance global and regional research and educational activities at UNM with a specific focus on a number of priority areas, including parasitic diseases, vector-borne diseases, HIV/AIDS, viral diseases, emerging infectious diseases, health systems research, and environmental health.  The Center aims to further foster collaborative relationships between UNM and our international partners for research, education, and service activities.

CLINICAL OPERATIONS  The CGH plans to take an active role in revitalizing and forming a top-tier Travel Medicine Clinic at UNM to serve the university and greater Southwest community.  We aim to expand the Global Health Residency track to enhance the clinical operations that the CGH has with our partners in India and Kenya.

ADMINISTRATION  To enhance and expand new faculty members and trainees in the CGH. With this anticipated growth, we look forward to continuous improvement, efficiency, and organizational management of the Center. Procedures, policies, and responsibilities related to the Center’s development, including personnel, research, logistical issues, and finances will be expedited for more efficient operational management.  Streamline administrative activities for the CGH and increase the membership base.  Hire two new NIH-funded faculty members into the Center in conjunction with the Division of Infectious Diseases, and additional DoIM divisions

APPOINTMENTS

FACULTY None

STAFF Name Title Effective date Dan Rogers Admin Assistant III 2/14/2012 Dukens LaBaze Lab Tech 6/21/2012

SEPARATIONS

FACULTY None

STAFF Name Title Effective date Lindsay Sullivan Admin Assistant II 11/23/2011

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PUBLICATIONS OF THE DIVISION AND FACULTY

Douglas Perkins, Ph.D. 1. Rivas AL, Fasina FO, Hoogesteyn AL, Konah SN, Febles JL, Perkins DJ, Hyman JM, Fair JM, Hittner JB, Smith SD. Connecting network properties of rapidly disseminating epizoonotics. PLoS One. 2012;7(6):e39778. Epub 2012 Jun 25. PMID: 22761900 2. Anyona SB, Kempaiah P, Raballah E, Davenport GC, Were T, Konah SN, Vulule JM, Hittner JB, Gichuki CW, Ong'echa JM, Perkins DJ. Reduced systemic bicyclo-prostaglandin-E(2) and cyclooxygenase-2 gene expression are associated with inefficient erythropoiesis and enhanced uptake of monocytic hemozoin in children with severe malarial anemia. Am J Hematol. 2012 Aug;87(8):782-9. doi: 10.1002/ajh.23253. Epub 2012 Jun 23. PMID: 22730036 3. Davenport GC, Hittner JB, Were T, Ong'echa JM, Perkins DJ. Relationship between inflammatory mediator patterns and anemia in HIV-1 positive and exposed children with Plasmodium falciparum malaria. Am J Hematol. 2012 Jul;87(7):652-8. doi: 10.1002/ajh.23200. Epub 2012 May 8. PMID: 22570198 4. Kempaiah P, Anyona SB, Raballah E, Davenport GC, Were T, Hittner JB, Ong'echa JM, Perkins DJ. Reduced interferon (IFN)-α conditioned by IFNA2 (-173) and IFNA8 (-884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality. Hum Genet. 2012 Aug;131(8):1375-91. Epub 2012 May 9. PMID: 22570109 5. Badu K, Afrane YA, Larbi J, Stewart VA, Waitumbi J, Angov E, Ong'echa JM, Perkins DJ, Zhou G, Githeko A, Yan G. Marked variation in MSP-119 antibody responses to malaria in western Kenyan highlands. BMC Infect Dis. 2012 Mar 1;12:50. PMID: 22380785 6. Davidson LB, Nessar R, Kempaiah P, Perkins DJ, Byrd TF. Mycobacterium abscessus glycopeptidolipid prevents respiratory epithelial TLR2 signaling as measured by HβD2 gene expression and IL-8 release. PLoS One. 2011;6(12):e29148. Epub 2011 Dec 21. PMID: 22216191 7. Perkins DJ, Were T, Davenport GC, Kempaiah P, Hittner JB, Ong'echa JM. Severe malarial anemia: innate immunity and pathogenesis. Int J Biol Sci. 2011;7(9):1427-42. Epub 2011 Nov 2. Review. PMID: 22110393 8. Anyona SB, Kempaiah P, Raballah E, Ouma C, Were T, Davenport GC, Konah SN, Vulule JM, Hittner JB, Gichuki CW, Ong'echa JM, Perkins DJ. Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality. Infect Immun. 2011 Dec;79(12):4923-32. Epub 2011 Oct 3. PMID: 21969001 9. Ong'echa JM, Davenport GC, Vulule JM, Hittner JB, Perkins DJ. Identification of inflammatory biomarkers for pediatric malarial anemia severity using novel statistical methods. Infect Immun. 2011 Nov;79(11):4674-80. Epub 2011 Aug 22. PMID: 21859849 10. Ong'echa JM, Raballah EO, Kempaiah PM, Anyona SB, Were T, Davenport GC, Konah S, Vulule JM, Ouma C, Hittner JB, Perkins DJ. Polymorphic variability in the 3' untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria. BMC Genet. 2011 Aug 6;12:69. PMID: 21819616 11. Ouma C, Davenport GC, Garcia S, Kempaiah P, Chaudhary A, Were T, Anyona SB, Raballah E, Konah SN, Hittner JB, Vulule JM, Ong'echa JM, Perkins DJ. Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children. Hum Genet. 2012 Feb;131(2):289-99. doi: 10.1007/s00439-011-1076-8. Epub 2011 Aug 5. PMID: 21818580

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Ravi Durvasula, M.D. 1. Hurwitz I, Fieck A, Durvasula R. Antimicrobial Peptide delivery strategies: use of recombinant antimicrobial peptides in paratransgenic control systems. Curr Drug Targets. 2012 Aug 1;13(9):1173-80. PMID: 22664074 2. Markiv A, Beatson R, Burchell J, Durvasula RV, Kang AS. Expression of recombinant multi-coloured fluorescent antibodies in gor -/trxB- E. coli cytoplasm. BMC Biotechnol. 2011 Nov 30;11:117. PMID: 22129156 3. Hurwitz I, Fieck A, Read A, Hillesland H, Klein N, Kang A, Durvasula R. Paratransgenic control of vector borne diseases. Int J Biol Sci. 2011;7(9):1334-44. Epub 2011 Nov 1. Review. PMID: 22110385

Prakasha Kempaiah, Ph.D. 1. Anyona SB, Kempaiah PM, Raballah E, Davenport GC, Were T, Konah SN, Vulule JM, Hittner JB, Gichuki CW, Ong'echa JM, Perkins DJ. Reduced systemic bicyclo-prostaglandin-E(2) and cyclooxygenase-2 gene expression are associated with inefficient erythropoiesis and enhanced uptake of monocytic hemozoin in children with severe malarial anemia. Am J Hematol. 2012 Aug;87(8):782-9. doi: 10.1002/ajh.23253. Epub 2012 Jun 23. PMID: 22730036 2. Kempaiah PM, Anyona SB, Raballah E, Davenport GC, Were T, Hittner JB, Ong'echa JM, Perkins DJ. Reduced interferon (IFN)-α conditioned by IFNA2 (-173) and IFNA8 (-884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality. Hum Genet. 2012 Aug;131(8):1375-91. Epub 2012 May 9. PMID: 22570109 3. Davidson LB, Nessar R, Kempaiah PM, Perkins DJ, Byrd TF. Mycobacterium abscessus glycopeptidolipid prevents respiratory epithelial TLR2 signaling as measured by HβD2 gene expression and IL-8 release. PLoS One. 2011;6(12):e29148. Epub 2011 Dec 21. PMID: 22216191 4. Perkins DJ, Were T, Davenport GC, Kempaiah PM, Hittner JB, Ong'echa JM. Severe malarial anemia: innate immunity and pathogenesis. Int J Biol Sci. 2011;7(9):1427-42. Epub 2011 Nov 2. Review. PMID: 22110393 5. Anyona SB, Kempaiah P, Raballah E, Ouma C, Were T, Davenport GC, Konah SN, Vulule JM, Hittner JB, Gichuki CW, Ong'echa JM, Perkins DJ. Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality. Infect Immun. 2011 Dec;79(12):4923-32. Epub 2011 Oct 3. PMID: 21969001 6. Ong'echa JM, Raballah EO, Kempaiah PM, Anyona SB, Were T, Davenport GC, Konah S, Vulule JM, Ouma C, Hittner JB, Perkins DJ. Polymorphic variability in the 3' untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria. BMC Genet. 2011 Aug 6;12:69. PMID: 21819616 7. Ouma C, Davenport GC, Garcia S, Kempaiah PM, Chaudhary A, Were T, Anyona SB, Raballah E, Konah SN, Hittner JB, Vulule JM, Ong'echa JM, Perkins DJ. Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children. Hum Genet. 2012 Feb;131(2):289-99. doi: 10.1007/s00439-011-1076-8. Epub 2011 Aug 5. PMID: 21818580

Julie Lovchik, Ph.D. 1. Lovchik JA, Drysdale M, Koehler TM, Hutt JA, Lyons CR. Expression of either lethal toxin or edema toxin by Bacillus anthracis is sufficient for virulence in a rabbit model of inhalational anthrax. Infect Immun. 2012 Jul;80(7):2414-25. Epub 2012 Apr 23. PMID: 22526673 2. Peachman KK, Li Q, Matyas GR, Shivachandra SB, Lovchik JA, Lyons RC, Alving CR, Rao VB, Rao M. Anthrax vaccine antigen-adjuvant formulations completely protect New Zealand white rabbits against challenge

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with Bacillus anthracis Ames strain spores. Clin Vaccine Immunol. 2012 Jan;19(1):11-6. Epub 2011 Nov 16. PMID: 22089245

Terry Wu, Ph.D. 1. Rozen WM, Ting JW, Leung M, Wu T, Ying D, Leong J. Advancing image-guided surgery in microvascular mandibular reconstruction: combining bony and vascular imaging with computed tomography-guided stereolithographic bone modeling. Plast Reconstr Surg. 2012 Jul;130(1):227e-9e. PMID: 22743942 2. Kapila S, Rozen WM, Huang T, Wu T, Fairbank S. Determining between chyle leak and anastomotic leak after esophageal reconstruction: the utility of methylene blue dye. Laryngoscope. 2012 Apr;122(4):779- 80. doi: 10.1002/lary.21732. Epub 2012 Feb 16. PMID: 22344866 3. Nuti DE, Crump RB, Dwi Handayani F, Chantratita N, Peacock SJ, Bowen R, Felgner PL, Davies DH, Wu T, Lyons CR, Brett PJ, Burtnick MN, Kozel TR, AuCoin DP. Identification of circulating bacterial antigens by in vivo microbial antigen discovery. MBio. 2011 Aug 16;2(4). pii: e00136-11. doi: 10.1128/mBio.00136-11. Print 2011. PMID: 21846829

OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

Douglas Perkins, Ph.D. INVITED LECTURES: REGIONAL OR NATIONAL  The Impact of Climate Change on Global Burden of Malaria: Memorias Del V Simposium de Immunoparasitologia, Mazatlan, Mexico  Decade Long Research in East Africa: Global Biosurveillance, Enabling Science and Technology, Los Alamos National Laboratories, Santa Fe, New Mexico  Pediatric Malarial Anemia in Kenya: Geo-epidemiology Workshop, The University of New Mexico Albuquerque, New Mexico  Molecular Targets for Novel Antimalarial Drugs: ynergy Meeting, Clinical and Translational Science Center, The University of New Mexico, Albuquerque, New Mexico

JOURNAL/EDITORIAL REVIEWER  Reviewer for, Journal of Infectious Diseases, Infection and Immunity, Blood, American Journal of Tropical Medicine and Hygiene, Lancet, Human Genetics, Trends in Parasitology, BMC Infectious Disease, Clinical Immunology, Acta Tropica, and Malaria Journal.

GRANT REVIEWER  International Centers for Malaria Research Excellence: National Institutes of Health, National Institute of Allergy and Infectious Diseases

COMMUNITY OUTREACH  Siaya District Sickle-cell Disease Project

PROFESSIONAL AFFILIATIONS  Member, Kenyatta University Academic and Student Advisory Committee, Nairobi, Kenya  Consultant, Defense Threat Reduction Agency, Department of Defense  Mentor/Advisor, GlaxoSmithKline, PULSE International Research Fellows  Founder and Director, Siaya District Community, Sickle-Cell Anemia Foundation, Siaya, Kenya  Member, American Society of Tropical Medicine and Hygiene

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 Member, American Society of Hematology  Member, American Society of Microbiology

Ravi Durvasula, M.D. AD HOC REVIEWER OR EDITORIAL CONSULTANT  Ad Hoc Reviewer, Insect Molecular Biology and Biochemistry  Ad Hoc Reviewer, Symbiosis  Ad Hoc Reviewer, American Journal of Public Health  Ad Hoc Reviewer for BARD, the United States – Israel Binational Agricultural Research & Development Fund  Ad Hoc Reviewer for NSERC (Canada)

JOURNAL/EDITORIAL REVIEWER  Reviewer, American Journal of Tropical Medicine and Hygiene  Reviewer, Emerging Infectious Diseases

PROFESSIONAL AFFILIATIONS  Member, American Society of Tropical Medicine and Hygiene  Member, Burroughs Welcome Trust Fund Fellowship Committee, American Society of Tropical Medicine and Hygiene  Member, Tropical Medicine Research Center Study Section: NIH-NIAID (ad hoc 2011)

Prakasha Kempaiah, Ph.D. AD HOC REVIEWER OR EDITORIAL CONSULTANT  Ad hoc Reviewer: Journal of Human Parasitic Disease  Ad hoc Reviewer: Gene Regulation and Systems Biology

JOURNAL/EDITORIAL REVIEWER  Peer-review articles for International Journal publications in “Cancer Cell International”, “Breast Cancer”, “Biotechnology Progress”, “Journal of Cell Death”, “Immunology and Immunogenetics Insights”, “Gene Expression to Genetical Genomics“ and “Cancer Informatics” journals.

Julie Lovchik, Ph.D. PROFESSIONAL AFFILIATIONS  Member, American Society for Microbiology

Terry Wu, Ph.D. JOURNAL/EDITORIAL REVIEWER  Editorial board member for Journal of Vaccine and Vaccination

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OUTSIDE SPONSORED RESEARCH

Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total B. Anthracis: Passive Lovchik, University of Nevada at Immunization with Non-Mission UNR-09-63, Amd. 3 12/1/2010 11/30/2012 4,974 9,948 14,922 Julie Reno Anticapsular Specific Antibodies B. Anthracis: Passive Lovchik, University of Nevada at Immunization with Non-Mission UNR-09-63 A4 12/1/2010 11/30/2012 61,560 123,120 184,680 Julie Reno Anticapsular Specific Antibodies NIH/National Institute UNM Animal Lovchik, of Allergy and Modeling Center - Research HHSN2722010000371 3/22/2010 3/21/2017 16,667 33,333 50,000 Julie Infectious Diseases Mimimum $50K NIH/National Institute Pulmonary Responses Lovchik, of Allergy and to Bioweapon Research 5P01AI056295-05 7/1/2010 6/30/2012 0 0 0 Julie Infectious Diseases Category A Pathogens NIH/National Institute Lovchik, Therapeutic Anti- of Allergy and Research Lovchik/14445 4/1/2010 3/31/2012 11,808 23,382 35,190 Julie Capsular Ab Candiates Infectious Diseases Discovery and Preclinical Lovchik, University of Alabama Development of Drugs Research 000263584-002 9/1/2010 8/31/2011 22,473 44,946 67,419 Julie at Birmingham for Anthrax, Plague and Tularemia Lovchik, Mouse Pulmonary Stanford University Research 26945890-35955-B 1/1/2011 8/24/2011 21,275 39,400 60,675 Julie Anthraw Challenge ARRA: UNM Perkins, NIH/Fogarty Framework Program Education R25TW008099-02 5/1/2010 4/30/2012 9,999 124,992 134,991 Douglas J. International Center in Global Health ARRA: UNM Perkins, NIH/Fogarty Framework Program Education R25TW008099-02 5/1/2011 4/30/2012 0 0 0 Douglas J. International Center in Global Health Training and Research Perkins, NIH/Fogarty on Severe Malarial Research 5D43TW005884-08 4/1/2010 3/31/2012 3,072 126,270 129,342 Douglas J. International Center Anemia NIH/National Institute Genetic Basis of Perkins, of Allergy and Severe Malarial Research 5R01AI0513058-08 4/1/2010 3/31/2012 115,950 441,473 557,423 Douglas J. Infectious Diseases Anemia

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Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total Training and Research Perkins, NIH/Fogarty on Severe Malarial Research D43TW005884-09 4/1/2011 3/31/2012 4,924 124,418 129,342 Douglas J. International Center Anemia NIH/National Institute Genetic Basis of Perkins, of Allergy and Severe Malarial Research R01AI051305-09 4/1/2011 3/31/2012 99,166 406,855 506,021 Douglas J. Infectious Diseases Anemia NIH/National Institute Genetic Basis of Perkins, of Allergy and Severe Malarial Research R01AI051305-09 4/1/2011 3/31/2012 9,104 18,208 27,312 Douglas J. Infectious Diseases Anemia NIH/National Institute Tularemia Vaccine Non-Mission HHSN266200500040C Wu, Terry of Allergy and 10/1/2010 9/29/2011 317,193 3,457,876 3,775,069 Development Team Specific Modification #11 Infectious Diseases NIH/National Institute Tularemia Vaccine HHSN26620050040C Wu, Terry of Allergy and Research 3/1/2011 12/31/2011 0 0 0 Development Team N01-AI-50040 Infectious Diseases Development of Vaccines against Defense Threat Wu, Terry Respiratory Infections Research HDTRA1-11-1-0049 6/15/2011 6/14/2012 70,796 429,489 500,285 Reduction Agency by Virulent Francisella Tularensis Task Order 1: Efficacy Testing of SRI 76-000044/Task Wu, Terry SRI International Compounds in Fischer Research 3/21/2011 4/30/2011 5,355 9,916 15,271 Order 1 344 Rat Respiratory Tularemia Model Task Order 1: Efficacy Testing of SRI 76-000044/Task Wu, Terry SRI International Compounds in Fischer Research 5/1/2011 6/15/2011 0 0 0 Order 1 344 Rat Respiratory Tularemia Model Systems Biology in 3D: Monitoring and Sandia National Modeling Dynamics of Wu, Terry Research SPO 1099250 2/9/2011 9/30/2011 10,859 21,373 32,232 Laboratories Francisella Tularensis- associated Granuloma Formation

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Faculty Sponsor Name Project Title Project type Sponsor Number Start Stop F A Direct Total Task 2: Efficacy Testing of SRI 76-000044/Task Wu, Terry SRI International Compounds in Fischer Research 5/10/2011 7/29/2011 5,355 9,916 15,271 Order 2 344 Rat Respiratory Tularemia Model Task Order 3: Efficacy Testing of SRI 76-000044/Task Wu, Terry SRI International Compounds in Fischer Research 6/6/2011 7/29/2011 5,419 9,852 15,271 Order 3 344 Rat Respiratory Tularemia Model

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CENTER FOR OCCUPATIONAL AND ENVIRONMENTAL HEALTH PROMOTION ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Denece O. Kesler, MD, MPH Professor of Medicine Medical Director, Center for Occupational and Environmental Health Promotion (COEHP)

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

The Center for Occupational and Environmental Health Promotion (COEHP) continues to provide services in three vital areas to UNM and to community partners. The three service areas are outlined as follows:

 Clinical Services: The Employee Occupational Health Services (EOHS) clinic provides occupational and environmental health clinical services, with Dr. Heidi Roeber Rice as the Medical Director.  Database and Compliance Services: Databases required for departmental or regulatory purposes are developed and maintained, with Joseph Shealy serving as the manager.  Consultative Services: Services are provided to a variety of departments in such areas as development of policies and procedures involving occupational and environmental health. Patricia Shuman is the manager of the Consultative Services.  The research and education programs in occupational and environmental medicine are components of COEHP under the Program in Occupational and Environmental Health (POEH).

EDUCATION  The UNM Public Health and General Preventive Medicine Residency program was successfully accredited by the ACGME Preventive Medicine Residency Review Committee. The first residents began on 7/1/11.  Dr. Kesler is the Program Director and Dr. Heidi Roeber Rice is the Associate Program Director for the preventive medicine residency program.

RESEARCH AND SCHOLARLY ACTIVITIES  Dr. Kesler and Dr.Roeber Rice are involved in research and scholarly activities which are reported under the Division of Epidemiology and Preventive Medicine report.

CLINICAL OPERATIONS  The EOHS clinic successfully fulfills the mission of serving the employee population of UNM and it’s partners in the community.

ADMINISTRATION  Dr. Kesler continues as the UNM Chief Risk Officer and chair of the Enterprise Risk Management (ERM) Council.

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

EDUCATION  Curriculum development for the new residency program will continue over the next year now that the full resident complement is in place.

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CLINICAL OPERATIONS  EOHS will continue to expand the clinical services provided to ensure compliance with regulatory and University requirements.

ADMINISTRATION  Consultative Services: COEHP will continue to expand the services provided to UNM as well as to community partners, especially in the area of addressing the occupational and environmental medicine needs of researchers.

APPOINTMENTS

FACULTY None

STAFF Name Title Effective date Danielle Narnajo Office Assistant 2/13/2012 Sunne Preston Admin Assistant II 7/5/2011 Andrea Andersen Outreach Coordinator 9/1/2011

SEPARATIONS

FACULTY None

STAFF Name Title Effective date Norma Bojorquez Administrative Assistant III 2/17/2012 Katrina Guillen Outreach Coordinator 8/5/2011

PUBLICATIONS OF THE DIVISION AND FACULTY

Heidi Roeber Rice, M.D., M.P.H. 1. Roeber Rice H, Varkey P. What Immunizations Should I Offer to My Patients? A Primer on Adult Immunizations. JAPI 2011 59:568-572 2. McGovern P, Dagher R, Roeber Rice H, Gjerdingen D, Dowd B, Ukestad L, Lundberg U. A Longitudinal Analysis of Total Workload and Women’s Health After Childbirth. JOEM 2011 53(5):497-505 3. Haddad L, Khu HN, Bayingana R, Roeber Rice H, Strunk S, Allen S. Integration of couples’ voluntary counseling and testing and family planning in Kigali, Rwanda. Contraception 2011 84(3): 324 4. Baker B, Roeber Rice H, Bartels M. Phenoxyacetic Acid Herbicides. In: H.E. Hoffman, R.B. Palmer & S. Phillips (Eds.), Clinical Practice of Biological Monitoring (pp. 179-185). Beverly Farms, MA: OEM Press, 2012

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OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

Denece O. Kesler, MD PROFESSIONAL AFFILIATIONS  Elected member, American Board of Medical Specialties  Elected Chair, American Board of Preventive Medicine  Member, American College of Occupational and Environmental Medicine Competencies Task Force  Member, HSC Academic Affairs Advisory Committee

INVITED LECTURES: REGIONAL OR NATIONAL  “Becoming Board Certified and Maintaining Certification” presented 4/30/12 at the Annual Occupational Health Conference sponsored by the American College of Occupational and Environmental Medicine, Los Angeles, CA  “ABPM MOC Part IV Requirements and the ACOEM Program” presented 5/1/12 at the Annual Occupational Health Conference sponsored by the American College of Occupational and Environmental Medicine, Los Angeles, CA

Heidi Roeber Rice, MD PROFESSIONAL AFFILIATIONS  Member, Institutional Biosafety Committee  Member, Select Agents Committee

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OUTSIDE SPONSORED RESEARCH

Project Faculty Sponsor Name Project Title Sponsor Number Start Stop F A Direct Total type Development of a Medical Screening Kesler, 2000070550 Amend Johns Hopkins University Program for Former Clinical 2/1/2010 1/31/2011 0 0 0 Denece O. 3/4/5 Sandia and LANL Workers HRSA-Health Resources Radiation Exposure Kesler, and Services Screening and Education Clinical H1GRH00007-09-00 9/1/2010 8/31/2011 43,483 167,242 210,725 Denece O. Administration Program Lovelace Respiratory Kesler, Lovelace Respiratory Research Institute - Clinical PSA-11-13 5/1/2011 4/30/2012 0 6,000 6,000 Denece O. Research Institute Consulting Services Lovelace Respiratory Kesler, Lovelace Respiratory Research Institute - Clinical PSA-11-14 5/1/2011 4/30/2012 0 75,000 75,000 Denece O. Research Institute Occupational Medicine Services Development of a Medical Screening Kesler, 2000070550 Amend Johns Hopkins University Program for Former Clinical 2/1/2011 1/31/2012 0 0 0 Denece O. 3/4/5 Sandia and LANL Workers HRSA-Health Resources 2010 Preventive Kesler, and Services Medicine Residency Education D33HP19042-01-00 7/1/2010 6/30/2011 22,114 276,419 298,533 Denece O. Administration Program HRSA-Health Resources Radiation Exposure Non- Kesler, and Services Screening and Education Mission 5H1GRH00007-08-00 9/1/2009 8/31/2010 44,773 172,205 216,978 Denece O. Administration Program Specific Honeywell Aerospace of Non- Kesler, Honeywell Corporation Albuquerque - Clinician Mission PSA-11-04 5/1/2011 4/30/2012 0 2,500 2,500 Denece O. Services Specific New Mexico Kesler, New Mexico Department Occupational Health Research 10UNM/03.0038 10/1/2009 9/30/2010 156 2,844 3,000 Denece O. of Health Surveillance Program Kesler, New Mexico Department Occupational Health Research FY11UNM03.0038 7/1/2010 6/30/2011 313 5,687 6,000 Denece O. of Health Surveillance

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CENTER FOR PROJECT ECHO

ANNUAL REPORT: JULY 1, 2011 – JUNE 30, 2012

Sanjeev Arora, MD Professor of Medicine Director, Project ECHO

SIGNIFICANT DEVELOPMENTS DURING THE ACADEMIC YEAR 2011-2012

Project ECHO (Extension for Community Healthcare Outcomes) is a model for service delivery, education and evaluation. Primary care clinicians from rural and underserved areas and prisons are trained and mentored by ECHO’s multi-disciplinary team of medical specialists to deliver best-practice management of complex health conditions in their communities or correctional institutions using video-conferencing technology and case-based learning. A key component of the ECHO model is an innovation known as Knowledge Networks, in which the expertise of a single specialist is shared with numerous primary clinicians through teleECHO clinics, thereby increasing access to care in rural areas without having to recruit, retain or fund additional clinicians.

The mission of Project ECHO™ is to develop the capacity to safely and effectively treat chronic, common and complex diseases in rural and underserved areas and to monitor outcomes. We have been focusing on the following strategic priorities for this period:

 Continue to develop and expand access to subspecialty care for chronic, common and complex diseases throughout New Mexico by developing new clinical areas.  Continue to develop and expand access to subspecialty care for chronic, common and complex diseases throughout New Mexico by carrying out grand rounds, outreach and training opportunities that allow new healthcare providers to learn about Project ECHO™ and become Project ECHO™ partners.  Develop and implement a process to train interested stakeholders around the U.S. and world about Project ECHO™ in order to replicate the ECHO model in other health delivery systems.  Develop and test financial models that promote long-term sustainability of Project ECHO™.  Continue to collaborate with the Veterans Health Administration and the Department of Defense to integrate the ECHO model into these national healthcare delivery systems.  Continue to improve sustainability through Project ECHO™’s pilot project with Molina Healthcare to provide reimbursement to primary care providers for presenting cases to teleECHO clinics.  Continue to improve sustainability through Project ECHO™’s agreement with Medicaid to match funds from the State of New Mexico Human Services Division.  Contiue Project ECHO™’s two-year intragovernmental personnel agreement (IPA) either VA to fund the replication of the ECHO model in seven of the 22 Veterans Integrated Service Networks (VISNs).  Continue Project ECHO™’s collaboration with the UNMHSC Office of Continuing Medical Education to develop and implement a collaborative agreement to establish a national training program to teach the use of Direct Acting Antivirals (telaprevir and boceprevir).  Develop partnerships with health care clinicians in New Mexico.

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INTERNAL MEDICINE FACULTY IN PROJECT ECHO LEADERSHIP

Sanjeev Arora, MD  Director of Project ECHO™  Professor, Division of Gastroenterology

Karla Thornton, MD, MPH  Associate Medical Director of Project ECHO™  Associate Professor, Division of Infectious Diseases

Fredrick Hashimoto, MD  Director of Informatics of Project ECHO™  Professor Emeritus, Division of General Medicine

Glen Murata M.D.

 Associate Director for Research of Project ECHO™  Professor, Division of General Medicine

INTERNAL MEDICINE FACULTY MEMBERS AFFILIATED WITH PROJECT ECHO™ TELEECHO CLINICS  Arthur Bankhurst, M.D., Division of Rheumatology  Kathleen Colleran, M.D. , Division of Endocrinology  George Comerci, M.D., Division of General Medicine  Bart Cox, M.D., Division of Cardiology  Michelle Harkins, M.D., Division of Pulmonary, Critical Care and Sleep Medicine  Carla Herman, M.D., Division of Geriatrics and Palliative Medicine  Michelle Iandiorio, M.D., Division of Infectious Diseases  Jeremiah Kelly, M.D., Division of Geriatrics and Palliative Medicine  Janice Knoefel. M.D., Division of Geriatrics and Palliative Medicine  Lisa Marr, M.D., Division of Geriatrics and Palliative Medicine  Devon Neale, M.D., Division of Geriatrics and Palliative Medicine  John Rush Pierce, M.D., Division of Hospital Medicine  Karla Thornton, M.D., Division of Infectious Diseases  Elaine Thomas, M.D., Division of Infectious Diseases

EDUCATION Continuing Education Credits  7,563.5 AMA PRA Category 1 Credits - Continuing Medical Education  1,365 AMA PRA Category 1 Credits - Continuing Education  957.5 New Mexico Counseling and Therapy Practice Board - Continuing Education Units

ECHO Orientation Site Visits  Project ECHO™ has held twelve site visits for orienting stakeholders from organizations interested in replicating the ECHO Model.  Guests have from all over the nation as well as South America have traveled to Albuquerque to participate.  These visits have an average participation of 30 guests per, totally over 350 visitors.

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RESEARCH AND SCHOLARLY ACTIVITIES  Project ECHO™ provided a book chapter outlining the ECHO model’s knowledge networks as an effective way to treat complex diseases in rural communities for volume 7 of the anthology Innovation and Change in Professional Education.  An overview of Project ECHO™’s Diabetes and Cardiovascular Care TeleECHO Clinic was published in the Diabetes Educator journal  An overview of Project ECHO™’s Asthma TeleECHO Clinic was published in US Respiratory Diseases.

CLINICAL OPERATIONS

Overall ECHO Clinic Statistics  890 total hours ECHO clinics  853 new patient consultations  704 follow-u patient consultations  1691 the number of physicians, nurses and other healthcare workers registered as partners in project  An increased from 1069 in FY 2011 to 1691 in FY 2012

Project ECHO TeleECHO Clinics for the period 7/1/2011 to 6/30/2012  Chronic Pain and Headache, 47 clinics, 1021 attendances  Community Addictions Recovery Specialist, 19 clinics, 329 attendances  Complex Care Clinic, 13 clinics, 136 attendances  Dementia Care Clinic, 21 clinics, 262 attendances  Diabetes and Cardiovascular Care (or Risk Reduction), 44 clinics, 678 attendances  Diabetes CHW Training Clinic, 27 clinics, 132 attendances  Heart Failure, 20 clinics, 132 attendances  Hepatitis C - Community, 52 clinics, 1010 attendances  Hepatitis C - Corrections, 31 clinics, 501 attendances  High Risk Pregnancy, 27 clinics, 446 attendances  HIV/AIDS, 50 clinics, 1399 attendances  Integrated Addiction / Psychiatry, 49 clinics, 809 attendances  New Mexico Peer Education Program, 8 clinics, 321 attendances  Palliative Care, 22 clinics, 302 attendances  Pulmonary / Asthma, 24 clinics, 212 attendances  Rheumatology, 46 clinics, 336 attendances

COMMUNITY ACTIVITIES  Project ECHO™ and Arthur Bankhurst, MD, Professor of Medicine and Chief of Rheumatology in the Department of Internal Medicine, were featured in the July 2011 issue of The Rheumatologist (ACR/ARHP), "Innovation Brings Specialist Services to the Underserved: Project ECHO trains general practitioners and midlevel providers in the basic arts of rheumatology".  Project ECHO™ highlighted on Discovery Channel "Health IT: Advancing Care, Empowering Patients" made its debut on the Discovery Channel on Saturday, November 19, 2011 at 6 a.m. (MST). The series showcased Project ECHO as a leading-edge project. Olivier Uyttebrouck, published an article on Project ECHO™ titled “Tele-Traetments” in the Albuquerque Journal (Dec. 30, 2011).  Dr Arora discussed Project ECHO™ on KOB-TV’s “Eye on Mew Mexico” on January 22, 2012.  Internal Medicine News published an article on Project ECHO™ titled “Project Walks Primary Care Providers Through Toughest Cases” (April 15, 2012).  The Albuquerque Journal published an article on Project ECHO™ tilted “Worst-Off Patients Get More Help” (May 12, 2012).

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ADMINISTRATION  During FY 2012 ECHO worked with the Robert Wood Johnson Foundation and business planner Roger King to develop ideas for new and consistent funding streams to create a sustainable business paln for the ECHO model.

HONORS AND AWARDS  Project ECHO™ has been awarded nearly $8.5 million over three years from the U.S. Department of Health and Human Services (HHS) Health Care Innovation awards. UNM will identify 5,000 high-cost, high- utilization, high-severity patients in New Mexico and Washington State, and use a team of primary care “intensivists” trained to care for complex patients with multiple chronic diseases, working with area managed care organizations and care providers. Project ECHO will train as many as 300 workers to help increase primary care physicians’ capacity to treat and manage complex patients. This new project will launch and funds will be released in FY 2013.  A paper describing Project ECHO™’s groundbreaking work to improve access to care for patients with hepatitis C has been named among the Most Influential Research Articles of 2011 by the Robert Wood Johnson Foundation. "Outcomes of Treatment for Hepatitis C Virus Infection by Primary Care Providers" by Project ECHO™ founder Sanjeev Arora, MD, and other Project ECHO™ researchers was published in June 2011 in The New England Journal of Medicine. The paper was one of 20 articles selected by RWJF from research conducted by the foundation's grantees; the paper was voted one of the Final 5 by visitors to the Foundation’s website.  The UNM ECHO team, in collaboration with MEDCOM staff, will develop and implement Army Medicine ECHO within the guidelines of the Office of the Surgeon General's Comprehensive Pain Management Campaign Plan (CPMCP). The Army Medicine ECHO initiative will provide Army Medicine with a model to address a myriad of diseases/conditions where synchronization of practice and optimization of specialty care/primary care resources are critical. The goal of CPMCP is to develop a standardized approach to Pain Management that optimizes the care for United States Army warriors and their families stationed world- wide.  Entered into an agreement with Molina to develop and launch a Complex Care TeleECHO Clinic.  Was given funds from Vision Quest for retinal imaging given by Community Health workers as part of the Diabetes and Cardiovascular Care TeleECHO Clinic.  Entered into an agreement with the New Mexico Human Services Department to create a Medicaid match for Project ECHO™.

APPOINTMENTS

FACULTY None

STAFF Name Title Effective date Katherine Thannish Coord. Dist. Education 7/15/2011 Elizabeth Martinez User Support Analyst 08/15/2011 Nathan Huff Data Analyst 03/05/2012 Deeann Lindsey Coord. Dist. Education 04/16/2012

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SEPARATIONS FACULTY - None

STAFF Name Title Effective date Megan Mullen Research Assistant 7/2/2011 Elizabeth Martinez User Support Analyst III 9/17/2011 Lisa Sullivan Admin. Asst. III 12/9/2011 Bonnie Mount Nurse Manager 1/7/2012 Julie Rosen Education and Research Manager 1/31/2012 Raquel Calderon Admin. Asst. III 2/17/2012 Antoinette Sabedra Admin. Asst. III 2/24/2012 Emmanuel Flores Database Administrator 3/30/2012 Denise Tafoya User Support Analyst 5/12/2012 Deeann Lindsay Coord. Dist. Education 5/19/2012 Lindsay Heizler Data Analyst 5/23/2012 John Brown Operations Director 5/30/2012 Katherine Tannish Coord. Dist. Education 6/1/2012

SIGNIFICANT PLANS AND RECOMMENDATIONS FOR THE NEAR FUTURE

EDUCATION  Continue providing Continuing Medical Education credits at no charge to participating TeleECHO clinicians  Continue to develop the monthly orientation visits.

RESEARCH AND SCHOLARLY ACTIVITIES  Develop an operational plan and create an effective team to lead and implement the CMMI grant. This will include building relations with medical care organizations and Medicaid in both New Mexico and Washington. This will also include identifying patients for the new program and creating a strong evaluation team to measure foe cost effectiveness.  Continue to publish academic journal articles on the positive outcomes and effectiveness of the ECHO model and TeleECHO clinics.

CLINICAL OPERATIONS  Continue to develop Project ECHO™’s TeleECHO clinic curriculum.  Continue to develop Project ECHO™’s TeleECHO clinics and expand partnerships with clinicians throughout New Mexico and the United States.

COMMUNITY ACTIVITIES  Continue to spread awareness of the ECHO model through various public forums such as invited lectures, interviews and a new quarterly newsletter.

ADMINISTRATION  Continue to develop the ECHO model within the Veterans Administration SCAN ECHO Project.  Continue to develop the ECHO model within the Department of Defense, both nationally and internally.  Continue working with the New Mexico Human Services Department to further develop the Medicaid match for Project ECHO™  Establish funding streams beyond FY2014.

.HONORS AND AWARDS  Continue to apply for funding through various grant awards and contracts.

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PUBLICATIONS OF THE DIVISION AND FACULTY

Sanjeev Arora, MD 1. Arora S, Kalishman S, Dion D, Thornton K, Murata G, Fassler C, Jenkusky SM, Parish B, Komaromy M, Pak W, Brown J. “Chapter 3: Knowledge Networks for Treating Complex Diseases in Remote, Rural, and Underserved Communities.” In Learning Trajectories, Innovation and Identity for Professional Development, edited by A. McKee & M. Eraut, pp. 47-70. Vol. 7 of Innovation and Change in Professional Education. New York: Springer, 2012. 2. Colleran K, Harding E, Kipp BJ, Zurawski A, Macmillan B, Jelinkova L, Kalishman S, Dion D, Arora S. “Building capacity to reduce disparities in diabetes: training community health workers using an integrated distance learning model,” Diabetes Educ. 2012 May;38(3):386-96. 3. Shah SK, Arora S, Skipper B, Kalishman S, Timm TC, Smith AY. “Randomized evaluation of a web based interview process for urology resident selection,” J Urol 2012 Apr;187(4):1380-4. 4. Thompson AJ, Patel K, Chuang WL, Lawitz EJ, Rodriguez-Torres M, Rustgi VK, Flisiak R, Pianko S, Diago M, Arora S, Foster GR, Torbenson M, Benhamou Y, Nelson DR, Sulkowski MS, Zeuzem S, Pulkstenis E, Subramanian GM, McHutchison JG; ACHIEVE-1 and ACHIEVE-2/3 Study Teams. “Viral Clearance is Associated with Improved Insulin Resistance in Genotype 1 Chronic Hepatitis C but Not Genotype 2/3,” Gut. 2012 Jan;61(1):128-134. 5. Harkins MS, Raissy H, Moseley K, Luttecke K, Arora S. “Extension for Community Healthcare Outcomes Project – Asthma Specialty Consultation Via Telehealth to Improve Asthma Care in rural New Mexico, “ US Respiratory Diseases. 2011;7(1):7-9. 6. Deming P, Arora S. “Tarbavirin in the Treatment of Hepatitis C” Informa Healthcare. Expert Opin Investig Drugs. 2011 Oct;20(20):1435-43.

Glen Murata M.D. 1. Arora S, Kalishman S, Dion D, Thornton K, Murata G, Fassler C, Jenkusky SM, Parish B, Komaromy M, Pak W, Brown J. “Chapter 3: Knowledge Networks for Treating Complex Diseases in Remote, Rural, and Underserved Communities.” In Learning Trajectories, Innovation and Identity for Professional Development, edited by A. McKee & M. Eraut, pp. 47-70. Vol. 7 of Innovation and Change in Professional Education. New York: Springer, 2012.

Karla Thornton, MD, MPH 1. Arora S, Kalishman S, Dion D, Thornton K, Murata G, Fassler C, Jenkusky SM, Parish B, Komaromy M, Pak W, Brown J. “Chapter 3: Knowledge Networks for Treating Complex Diseases in Remote, Rural, and Underserved Communities.” In Learning Trajectories, Innovation and Identity for Professional Development, edited by A. McKee & M. Eraut, pp. 47-70. Vol. 7 of Innovation and Change in Professional Education. New York: Springer, 2012.

OUTSIDE PROFESSIONAL ACTIVITIES OF FACULTY AND STAFF

Sanjeev Arora, MD INVITED LECTURES: REGIONAL OR NATIONAL  VA Medical Center, Grand Junction, CO, “SCAN ECHO”, May 29, 2012.  AASLD Governing Board at DDW 2012, San Diego, CA, “Extending Hepatology Care”, May 19, 2012.  AASLD/AGA Combined Clinical Symposium at DDW 2012, San Diego, CA, “New Therapies against HCV: Practitioners Delivering Specialty Care”, May 19, 2012.  European Association for the Study of Liver Disease (EASL), Barcelona, Spain, Joint Symposium: Global Public Health Burden: Impact of Viral Hepatitis, “Expanding Access to Treatment for Viral Hepatitis – Project ECHO”, April 20, 2012.

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 2012 Statewide Viral Hepatitis Conference, New York, NY, “Replicating ECHO – A model to expand access to primary care treatment of viral hepatitis”, March 20, 2012.  American Academy of Pain Medicine 2012 Annual Meeting, Palm Springs, CA, “Project ECHO (Extension for Community Healthcare Outcomes): Bridging the Gap between Urban Healthcare Specialists and Providers in Rural Settings”, February 24, 2012.  AASLD Liver Meeting 2011, San Francisco, CA, “HCV Symposium: Integrating HCV Practice Guidelines and Treatment Advances into Clinical Practice”, November 7, 2011.  Viral Hepatitis Action Coalition Meeting, San Francisco, CA, “Project ECHO- Expanding Access to Treatment for Hepatitis C”, November 4, 2011.  2011 New Mexico Chapter of the ACP Scientific Meeting, Albuquerque, NM, “Enhancing the Management of Liver Disease in New Mexico”, October 28, 2011.  University of New Mexico Update and Review of Internal Medicine 2011, Santa Fe, NM, “Disruptive Innovation in Healthcare”, October 18, 2011.  University of New Mexico Update and Review of Internal Medicine 2011, Santa Fe, NM, “Gastroenterology Q & A”, October 16, 2011.  University of New Mexico Update and Review of Internal Medicine 2011, Santa Fe, NM, “Answering Your Questions”, October 16, 2011.  University of New Mexico Update and Review of Internal Medicine 2011, Santa Fe, NM, “Chronic Hepatitis C: The Silent Epidemic”, October 16, 2011.  ACP Fall Board of Governor’s Meeting, San Antonio, TX, “Extension for Community Health Outcomes (Project ECHO)”, September 22, 2011.  Transforming Hepatitis C Care in VA: Integrating HCV Protease Inhibitors into Anti-Viral Treatment, Dallas, TX, “Project ECHO”, September 9, 2011.  World Hepatitis Day Meeting at the White House, Washington DC, “Panel 2 Discussion: Voices of Providers and Patients”, July 28, 2011.  Pacific AIDS Education and Training Center, Oakland, CA, “Project ECHO”, July 26, 2011.  Midwest CTSA Consortium, Chicago, IL, “Project ECHO; Comparative Effectiveness of Innovative Approaches to Addressing Healthcare Disparities in Underserved Areas", July 7, 2011.

PROFESSIONAL AFFILIATIONS  Fellow, American College of Gastroenterology  Fellow, American Gastroenterology Association  Fellow, American College of Physicians--American Society of Internal Medicine  Member, American Association for the Advancement of Sciences  Fellow, American College of Gastroenterology  American Society for Gastrointestinal Endoscopy (ASGE)  Member, Greater Albuquerque Medical Association  American Association for the Study of Liver Diseases  Member, European Association for the Study of the Liver

Fredrick Hashimoto, MD COMMUNITY OUTREACH  New Mexico Athletic Association (and Albuquerque Academy) swim meet official, 1997-present  music: Big Bad Band (swing and jazz band), Windbags (sax quartet): public performances, 2003-present  New Mexico Swimming, meet official, 1995-present

PROFESSIONAL AFFILIATIONS  Member of the Professional Chemical Fraternity Alpha Chi Sigma

Glen Murata M.D. COMMUNITY OUTREACH  Board of Directors, Lovelace Clinic Foundation, 2010 – present

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PROFESSIONAL AFFILIATIONS  Phi Beta Kappa  Alpha Omega Alpha  American College of Physicians  Society of General Internal Medicine  American Diabetes Association

Karla Thornton, MD, MPH INVITED LECTURES: REGIONAL OR NATIONAL  Iandiorio, M., Tessmann, T., Thornton, K., Brown, J, Arora S. Innovations in Provider HIV Education. Annual International AIDS Impact Conference. 9/12-9/15/2011, Santa Fe, NM, Poster Presentation.  Karla Thornton, MD, Sanjeev Arora, MD, Glen Murata, MD. Abstract number 217283. Project ECHO: Outcomes of Hepatitis C Treatment by Primary Care Providers. 18th International Symposium on Hepatitis C Virus and Related Viruses. Seattle, WA. September 8-12, 2011. Oral Presentation.  7/2011. Hepatitis C: The Importance of Testing and Treating. World Hepatitis C Day, Espanola, NM. Sponsor: El Centro Family Health.  4/2012. HCV Update on Testing and Treatment. Las Clinicas del Norte, El Rito, NM.  2/2012. HCV Update. HIV Curriculum, Infectious Diseases Fellows, Albuquerque, NM. Sponsor: NM AIDS Education and Training Center.

PROFESSIONAL AFFILIATIONS  American Association for the Study of Liver Diseases, 2008-present  National Infectious Disease Society of America (IDSA). 1999-present.  Infectious Diseases Society of New Mexico. 1999 -present.

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OUTSIDE SPONSORED RESEARCH

Project Faculty Sponsor Name Project Title Sponsor Number Start Stop F A Direct Total type A Robust Paradigm to Robert Wood Arora, Expand Best Practice for Johnson Clinical 63945 2/15/2009 2/14/2012 535,340 4,461,172 4,996,512 Sanjeev Vulnerable Populations Foundation (ECHO) Outreach Focused HRSA-Health Congressional Special Arora, Resources and Initiative: Improving Clinical D1ARH16079-01-00 9/1/2009 2/28/2011 24,988 149,252 174,240 Sanjeev Services Telehealth Infrastructure Administration Capacity in New Mexico New Mexico Arora, Department of Hepatitis C Project Clinical 12UNM02.0028 7/1/2011 6/30/2012 5,203 94,600 99,803 Sanjeev Health Arora, Project ECHO Services for Molina Clinical PA#17747 3/1/2012 2/28/2013 61,905 238,095 300,000 Sanjeev Complex Care Clinics Arora, Department of IPA: George Comerci Education IPA/G. Comeri 5/15/2012 5/14/2014 15,158 58,302 73,460 Sanjeev Defense Arora, Department of IPA: Jeanne Boyle Education IPA/J. Boyle 5/15/2012 5/14/2014 21,483 82,626 104,109 Sanjeev Defense Arora, Department of IPA: Ronselle Harrison Education IPA/R. Harrison 5/15/2012 5/14/2014 20,222 77,777 97,999 Sanjeev Defense Arora, Department of IPA: Joanna Katzman Education IAP/J. Katzman 5/15/2012 5/14/2014 118,793 456,895 575,688 Sanjeev Defense Arora, Department of IPA: Cynthia Olivas Education IAP/C. Olivas 5/15/2012 5/14/2014 49,145 189,017 238,162 Sanjeev Defense Arora, Department of IPA: Daniel Duhigg Education IAP/D. Duhigg 5/15/2012 5/14/2014 13,644 52,475 66,119 Sanjeev Defense Arora, Department of IAP: Sanjeev Arora Education IAP/S. Arora 5/15/2012 5/14/2014 21,377 82,218 103,595 Sanjeev Defense Arora, Department of IPA: Sanjeev Arora Education IPA/S. Arora 3/1/2011 2/28/2013 0 205,544 205,544 Sanjeev Veterans Affairs Arora, Department of IPA: Jeannie Boyle Education IPA/J. Boyle 3/1/2011 2/28/2013 0 118,035 118,035 Sanjeev Veterans Affairs Arora, Department of IPA: John Brown Education IPA/J. Brown 3/1/2011 2/28/2013 0 126,714 126,714 Sanjeev Veterans Affairs Arora, Department of IPA:Camille Chapman Education IPA/C. Chapman 3/1/2011 5/6/2011 0 92,579 92,579 Sanjeev Veterans Affairs

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Project Faculty Sponsor Name Project Title Sponsor Number Start Stop F A Direct Total type Arora, Department of IPA: Joanna Katzman Education IPA/J. Katzman 3/1/2011 2/28/2013 0 54,151 54,151 Sanjeev Veterans Affairs Arora, Department of IPA: Kathleen Colleran Education IPA/K. Colleran 3/1/2011 2/28/2013 0 43,553 43,553 Sanjeev Veterans Affairs Arora, Department of IPA Bart Cox Education IPA/B. Cox 4/1/2011 2/28/2013 0 70,159 70,159 Sanjeev Veterans Affairs Arora, Department of IPA: Karla Thornton Education IPA/K. Thornton 3/1/2011 2/28/2013 0 101,178 101,178 Sanjeev Veterans Affairs Arora, Department of IPA: Amy Hunter Baird Education IPA/A. Baird 3/1/2011 2/28/2013 0 80,673 80,673 Sanjeev Veterans Affairs Arora, Department of IPA: Chong Pak Education IPA/C. Pak 3/1/2011 2/28/2013 0 108,975 108,975 Sanjeev Veterans Affairs Arora, Department of IPA: Karen Gaines Education IPA/K. Gaines 7/1/2011 2/28/2013 0 67,785 67,785 Sanjeev Veterans Affairs Hepatitis C Treatment Arora, Expansion Initiative: USF Education PA#16778 9/1/2011 8/31/2012 23,983 92,241 116,224 Sanjeev Evaluation and Technical Assistance Retinal Imaging Via Arora, Vision Quest Community Heath Education PA#16779 9/5/2011 9/4/2012 10,317 39,683 50,000 Sanjeev Workers Prisoner Health is McClune Arora, Community Health: The Charitable Education PA#16963 5/12/2012 5/30/2013 0 15,000 15,000 Sanjeev NM Peer Education Foundation Project Non- Arora, Astra Merck Dept of Medicine Speaker Mission 144889 1/1/2010 12/31/2011 0 0 0 Sanjeev Pharmaceuticals Program Specific Arora, PPD Development Clinical Trial Research RNA003142-301 1/1/2010 12/31/2011 0 0 0 Sanjeev Arora, Exagen Research Agreement Research UNM 3/1/2009 2/28/2011 0 0 0 Sanjeev Diagnostics Arora, Idenix Clinical Trial Research NV08A-006 9/15/2006 12/31/2011 0 0 0 Sanjeev Pharmaceuticals Arora, Idenix Clinical Trial Research NV08A-006 9/15/2007 12/31/2013 0 0 0 Sanjeev Pharmaceuticals Arora, Duke University Clinical Trial Research Vertex-VX05-950-104 5/1/2009 4/30/2011 0 0 0 Sanjeev

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Project Faculty Sponsor Name Project Title Sponsor Number Start Stop F A Direct Total type Arora, Duke University Clinical Trial Research Vertex-VX05-950-104 5/1/2011 4/30/2013 0 0 0 Sanjeev Roche Arora, Clinical Trial Agreement Pharmaceuticals, Research MV21542 3/1/2009 12/31/2010 0 0 0 Sanjeev Phase III Inc. Vertex Arora, Pharmaceuticals Clinical Trial - Phase III Research VX07-950-108 2/29/2008 2/28/2013 33,129 132,514 165,643 Sanjeev Incorporated Tibotec Arora, Pharmaceuticals, Clinical Trial Phase III Research VX-950-TiDP24-C216 9/17/2008 9/16/2013 22,614 90,455 113,069 Sanjeev Ltd. Vertex Arora, Pharmaceuticals Clinical Trial - Phase III Research VX08-950-111 9/12/2008 9/11/2013 46,739 257,861 304,600 Sanjeev Incorporated Project ECHO Hepatitis C DHHS/Agency for Ambulatory Care Quality Arora, Healthcare Improvement in New Research R18HS018171-01 9/30/2009 7/31/2010 103,009 396,187 499,196 Sanjeev Research and Mexico through Health Quality Information Technology DHHS/Agency for Expansion of Rural Health Arora, Healthcare Care Research Research R24HS016510-03 9/1/2009 8/31/2010 103,175 396,825 500,000 Sanjeev Research and Infrastructure through Quality the ECHO Model DHHS/Agency for Expansion of Rural Health Arora, Healthcare Care Research Research R24HS016510-03 9/1/2010 8/31/2011 0 0 0 Sanjeev Research and Infrastructure through Quality the ECHO Model Vertex Arora, Pharmaceuticals Clinical Trial - Phase 3 Research VX08-950-112 11/6/2009 11/5/2012 8,151 32,614 40,765 Sanjeev Incorporated Roche Arora, Pharmaceuticals, Clinical Trial - Phase 2 Research NV22621 2/2/2010 10/20/2011 10,720 149,277 159,997 Sanjeev Inc. Arora, ZymoGenetics, Clinical Trial Agreement Research IL-29 526H04 2/18/2010 2/17/2013 23,297 199,800 223,097 Sanjeev Inc. Phase II

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Project Faculty Sponsor Name Project Title Sponsor Number Start Stop F A Direct Total type Project ECHO Hepatitis C Agency for Ambulatory Care Quality Arora, Healthcare Improvement in New Research R18HS018171-02 8/1/2010 7/31/2011 61,640 237,078 298,718 Sanjeev Research and Mexico through Health Quality (AHRQ) Information New Mexico Arora, Medicaid Match for Human Services Research GSA-11-630-8000-0020 7/1/2010 6/30/2011 29,484 597,832 627,316 Sanjeev Project ECHO Department Arora, Hoffmann-La Clinical Trial Phase 2 Research PP25213 2/22/2011 2/21/2016 50,058 200,230 250,288 Sanjeev Roche Inc. Arora, Gilead Sciences Clinical Trial Phase 2 Research GS-US-196-0140 4/5/2011 4/4/2016 71,119 284,473 355,592 Sanjeev Arora, Duke University Clinical Trial-Phase I Research COL-HCV-200 5/19/2011 5/18/2016 6,857 27,426 34,283 Sanjeev Arora, University of Project ECHO Technical Research 0000172626/0000175580 4/1/2011 8/30/2011 4,057 15,603 19,660 Sanjeev South Florida Agreement (HAN) Wyeth Arora, Pharmaceuticals, Clinical Trial Research 3173A1-200-US 10/12/2009 2/12/2012 0 0 0 Sanjeev Inc. Arora, Duke University Clinical Trial Research HGS1008-C1060 2/1/2010 3/27/2012 0 0 0 Sanjeev Vertex Arora, Pharmaceuticals Clinical Trial Research VX-950-106/107 2/26/2010 2/25/2013 0 0 0 Sanjeev Incorporated Arora, Duke University Clinical Trial Research HGS1008-C1067 3/1/2010 4/12/2012 0 0 0 Sanjeev New Mexico Arora, GSA-11-630-8000-0020 Human Services Clinical Trial Research 7/1/2011 6/30/2012 27,623 594,336 621,959 Sanjeev A1 Department Arora, SC Liver Research Clinical Trial Research HCV-01-11 4/1/2012 3/30/2015 13,534 67,677 81,211 Sanjeev Consortium Arora, Quintiles Clinical Trial Research P7977-0724 7/21/2011 7/20/2016 17,295 86,474 103,769 Sanjeev Laboratories Arora, GSA-11-630-8000-0020 Gilead Sciences Clinical Trial Research 10/5/2011 10/4/2016 20,859 104,290 125,149 Sanjeev A1 Arora, Gilead Sciences Clinical Trial Research 10/25/2011 10/24/2016 4,468 22,340 26,808 Sanjeev

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ACADEMIC DIRECTORY

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INTERNAL MEDICINE FACULTY 2011-2012 William Abeyta, M.D. Rebecca Bain, M.D. Associate Professor Assistant Professor General Medicine Hospital Medicine Jonathan Abrams, M.D. Arthur Bankhurst, M.D. Professor Emeritus Professor Cardiology Rheumatology

Abinash Achrekar, M.D. Jehad Barakat, M.D. Assistant Professor Associate Professor Cardiology Gastroenterology

William Adler, M.D. Julie Bauman, M.D. Assistant Professor Assistant Professor Hematology/Oncology Hematology/Oncology Allen Adolphe, M.D., Ph.D. Amanda Beck, M.D., Ph.D. Professor Professor General Medicine Pulmonary/Critical Care

Savitri Aguiar, M.D. Edward Bedrick, Ph.D. Assistant Professor Professor Hospital Medicine Epidemiology

Bina Ahmed, M.D. Peggy Beeley, M.D. Assistant Professor Professor Cardiology Hospital Medicine

Eduardo Alas, M.D. David Bennahum, M.D. Assistant Professor Professor Emeritus Nephrology Geriatrics

Joseph Alcorn, M.D. Jennifer Benson, M.D. Assistant Professor Assistant Professor Gastroenterology General Medicine

Rana Al-Sadi, Ph.D. Helbert Rondon Berrios, M.D. Research Assistant Professor Assistant Professor Gastroenterology Nephrology Mara Archambault, M.D. Marianne Berwick, Ph.D. Assistant Professor Professor General Medicine Epidemiology

Cynthia Arndell, M.D. Jessica Bigney, M.D. Associate Professor Professor General Medicine General Medicine

Sanjeev Arora, M.D. Janet Blanchard, M.D. Professor Assistant Professor Gastroenterology Hospital Medicine

Madhu Arora, M.D. Edgar Boedeker, M.D. Associate Professor Professor General Medicine Gastroenterology

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Internal Medicine Faculty (Continued)

Michel Boivin, M.D. Nathaniel Collins, M.D. Associate Professor Assistant Professor Pulmonary/Critical Care/Sleep Medicine Hospital Medicine Matthew Bouchonville, M.D. George Comerci, M.D. Assistant Professor Professor Endocrinology General Medicine

Lee Brown, M.D. Linda Cook, Ph.D. Professor Professor Pulmonary/Critical Care/Sleep Medicine Epidemiology

Julie Broyles, M.D. Ivan Correa, M.D Professor Assistant Professor General Medicine Geriatrics

Mark Burge, M.D. Ellen Cosgrove, M.D. Professor Professor Endocrinology General Medicine

Marcos Burgos, M.D. Bart Cox, M.D. Associate Professor Associate Professor Hospital Medicine Cardiology

Elizabeth Burpee, M.D. Richard Crowell, M.D. Assistant Professor Professor General Medicine Pulmonary/Critical Care/Sleep Medicine

Helen Busby, M.D. Herbert Davis, Ph.D. Associate Professor Research Professor Pulmonary/Critical Care/Sleep Medicine Epidemiology

Isaac Wyatt Byrd, Ph.D. Dana Davis, M.D. Research Assistant Professor Associate Professor Gastroenterology Hospital Medicine

Thomas Byrd, III, M.D. Zoneddy Dayao, M.D. Professor Assistant Professor Infectious Diseases Hematology/Oncology

Amandeep Chadha, M.D. Karol Dokladny, Ph.D. Assistant Professor Research Assistant Professor General Medicine Pulmonary/Critical Care/Sleep Medicine Betty Chang, M.D. Richard Dorin, M.D. Associate Professor Professor Pulmonary/Critical Care/Sleep Medicine Endocrinology

Gerald Charlton, M.D. Robert DuBroff, M.D. Associate Professor Assistant Professor Cardiology Cardiology

Jason Cohen, M.D. Terry Duclos, M.D., Ph.D. Assistant Professor Professor General Medicine Rheumatology

Kathleen Colleran, M.D. Ravi Durvasula, M.D. Professor Professor Endocrinology Global Health

226

Internal Medicine Faculty (Continued)

R. Eaton, M.D. Michael Gavin, M.D. Professor Emeritus Assistant Professor Endocrinology Gastroenterology Kevin Edwards, M.D. Meghan Gerety, M.D. Associate Professor Professor General Medicine Geriatrics Nicole Emil, M.D. Wendy Gerstein, M.D. Assistant Professor Associate Professor Hospital Medicine Hospital Medicine Edward Fancovic, M.D. James Gibb, M.D. Professor Assistant Professor General Medicine Nephrology M. Houman Fekrazad, M.D. Michael Gilles, M.D. Assistant Professor Assistant Professor Hematology/Oncology Gastroenterology Roderick Fields, M.D. Tamar Ginossar, Ph.D. Assistant Professor Research Assistant Professor Rheumatology Hematology/Oncology

Esme Finlay, M.D. Melissa Gonzales, Ph.D. Assistant Professor Associate Professor Hematology/Oncology Epidemiology

Holly Fleming, M.D. David. A. Gonzales, M.D. Associate Professor Assistant Professor Hospital Medicine Hospital Medicine Kristina Flores, Ph.D. David V. Gonzales, M.D. Research Assistant Professor Professor Emeritus Epidemiology General Medicine

Dana Fotieo, M.D. Ambreen Gul, M.D. Professor Assistant Professor General Medicine Nephrology

Gregory Fotieo, M.D. Shuhong Guo, Ph.D. Professor Research Assistant Professor General Medicine Gastroenterology

Robert Francis, M.D. Diane Hanfelt-Goade, M.D. Assistant Professor Associate Professor Hematology/Oncology Infectious Diseases Robert Fritch, D.O. Antonia Harford, M.D. Associate Professor Professor General Medicine Nephrology

David Garcia, M.D. Farzana Harji, M.D. Professor Associate Professor Hematology/Oncology Hospital Medicine Ann Gateley, M.D. Michelle Harkins, M.D. Professor Emeritus Associate Professor General Medicine Pulmonary/Critical Care/Sleep Medicine

227

Internal Medicine Faculty (Continued)

Frederick Hashimoto, M.D. Curtis Kapsner, M.D. Professor Emeritus Associate Professor General Medicine Nephrology

Cynthia Heins, M.D. Susan Kellie, M.D. Assistant Professor Professor General Medicine Infectious Diseases

David Hemphill, M.D. Jeremiah Kelly, M.D. Assistant Professor Assistant Professor Geriatrics Geriatrics

Carla Herman, M.D., MPH Prakasha Kempaiah, Ph.D. Professor Research Assistant Professor Geriatrics Global Health

Deirdre Hill, Ph.D. Denece Kesler, M.D., MPH Research Assistant Professor Professor Epidemiology Epidemiology

Richard Hoffman, M.D., MPH Sepehr Khashaei, M.D. Professor Assistant Professor Epidemiology Hospital Medicine Diedre Hofinger, M.D. Irena King, Ph.D. Assistant Professor Research Professor Hospital Medicine Epidemiology

Bruce Horowitz, M.D. Martin Kistin, M.D. Professor Professor Nephrology Gastroenterology

Michelle Iandiorio, M.D. Judith Kitzes, M.D., MPH Associate Professor Research Associate Professor Infectious Diseases Geriatrics

Milton Icenogle, M.D. Janice Knoefel, M.D., MPH Associate Professor Professor Cardiology Geriatrics Shmuel Inbar, M.D. Kevin Kolendich, M.D. Associate Professor Assistant Professor Cardiology Gastroenterology

Gary Iwamoto, M.D. Konstantin Konstantinov, M.D. Professor Associate Professor Pulmonary/Critical Care/Sleep Medicine Rheumatology

Jennifer Jernigan, M.D. Teodora Konstantinova, M.D. Associate Professor Assistant Professor General Medicine Hospital Medicine

Huining Kang, Ph.D. Erik Kraai, M.D. Assistant Professor Assistant Professor Epidemiology Hospital Medicine

Patricia Kapsner, M.D. Jens Langsjoen, M.D. Professor Assistant Professor Endocrinology Hospital Medicine

228

Internal Medicine Faculty (Continued)

Warren Laskey, M.D. Lisa Marr, M.D. Professor Associate Professor Cardiology Geriatrics Richard Lauer, M.D. Melissa Martinez, M.D. Professor Professor Hematology/Oncology General Medicine

Fa-Chyi Lee, M.D. Denis McCarthy, M.D. Professor Professor Hematology/Oncology Gastroenterology Sang-Joon Lee, Ph.D. Elizabeth McGuire, M.D. Assistant Professor Associate Professor Epidemiology Hematology/Oncology Samuel Lee, M.D. Lana Melendres-Groves, M.D. Associate Professor Assistant Professor Infectious Diseases Pulmonary/Critical Care/Sleep Medicine Wanli Lei, Ph.D. Rishi Menon, M.D. Research Assistant Professor Assistant Professor Gastroenterology Hospital Medicine

Margaret Lieberman, M.D. Gregory Mertz, M.D. Assistant Professor Professor General Medicine Infectious Diseases Benny Liem, M.D. Robert Mickelsen, M.D. Assistant Professor Assistant Professor Hematology/Oncology Hospital Medicine Henry Lin, M.D. Sheila Modi, M.D. Professor Assistant Professor Gastroenterology Hospital Medicine Robert Lindeman, M.D. Ann Morrison, M.D. Professor Emeritus Professor Geriatrics General Medicine Julie Lovchik, Ph.D. Pope Moseley, M.D. Research Assistant Professor Professor Global Health Pulmonary/Critical Care/Sleep Medicine

Li Luo, Ph.D. Robert Munk, Ph.D. Research Assistant Professor Research Assistant Professor Epidemiology Infectious Diseases Thomas Ma, M.D., Ph.D. Glen Murata, M.D. Professor Professor Gastroenterology General Medicine Aroop Mangalik, M.D. Cristina Murray-Krezan, B.A., M.S. Visiting Professor Research Assistant Professor Hematology/Oncology Epidemiology

Jenny Mao, M.D. Orrin Myers, Ph.D. Professor Research Associate Professor Pulmonary/Critical Care/Sleep Medicine Epidemiology

229

Internal Medicine Faculty (Continued)

Devon Neale, M.D. Arti Prasad, M.D. Assistant Professor Professor Geriatrics General Medicine

Betty Newville, M.D. Sandra Qaseem, M.D. Assistant Professor Assistant Professor Hospital Medicine Geriatrics

Prashant Nighot, Ph.D. Dulcinea Quintana, M.D. Research Assistant Professor Assistant Professor Gastroenterology Hematology/Oncology Leonard Noronha, M.D. Ian Rabinowitz, M.D. Assistant Professor Professor Hospital Medicine Hematology/Oncology

Toru Nyunoya, M.D. Shazia Rafiq, M.D. Assistant Professor Assistant Professor Pulmonary/Critical Care/Sleep Medicine Gastroenterology

David Olson, Jr., M.D. Veena Raizada, M.D. Associate Professor Professor Hospital Medicine Cardiology

Larry Osborn, M.D. Frank Ralls, M.D. Visiting Professor Assistant Professor Cardiology Pulmonary/Critical Care/Sleep Medicine

Gulshan Parasher, M.D. Deepti Rao, M.D. Associate Professor Assistant Professor Gastroenterology Hospital Medicine

Donna Jean Parker, M.D. Kanwaldeep Rasila, M.D. Assistant Professor Assistant Professor Geriatrics Hematology/Oncology

Yehuda Patt, M.D. D. Michelle Ratliff, M.D. Professor Associate Professor Hematology/Oncology Cardiology Percy Pentecost, M.D. Mark Ricciardi, M.D. Assistant Professor Associate Professor Hospital Medicine Cardiology

Mel Peralta, M.D. Heidi Roeber Rice, M.D. Assistant Professor Assistant Professor Cardiology Epidemiology Douglas Perkins, Ph.D. Kendall Rogers, M.D. Professor Associate Professor Global Health Hospital Medicine

Rush Pierce, M.D. Mark Rohrscheib, M.D. Associate Professor Associate Professor Hospital Medicine Nephrology Arun V. Pillai, M.D. Carlos Roldan, M.D. Assistant Professor Professor Gastroenterology Cardiology

230

Internal Medicine Faculty (Continued)

Melanie Royce, M.D., Ph.D. J. Mitchell Simson, M.D. Professor Associate Professor Hematology/Oncology General Medicine

John Rushton, Ph.D. Pooja Singh, M.D. Research Assistant Professor Assistant Professor Epidemiology/Global Health Nephrology Ali Saeed, M.D. Akshay Sood, M.D., MPH Assistant Professor Associate Professor Pulmonary/Critical Care/Sleep Medicine Pulmonary/Critical Care/Sleep Medicine

John Saiki, M.D. Christine Stidley, Ph.D. Professor Emeritus Professor Hematology/Oncology Epidemiology

Annahita Sallmyr, Ph.D. Robert Strickland, M.D. Research Assistant Professor Professor Emeritus Hematology/Oncology Gastroenterology

Sagus Sampath, M.D. Eric Stone, M.D. Assistant Professor Assistant Professor Hematology/Oncology Gastroenterology

Subhajlt Sarkar, M.D. Yijuan Sun, M.D. Assistant Professor Assistant Professor Hospital Medicine Nephrology

David Schade, M.D. Corey Tancik, M.D. Professor Professor Endocrinology General Medicine

Thomas Schroeder, M.D. Amy Tarnower, M.D. Assistant Professor Associate Professor Hematology/Oncology Hematology/Oncology Mark Schuyler, M.D. Robert Taylor, M.D. Professor Associate Professor Pulmonary/Critical Care/Sleep Medicine Cardiology

Karen Servilla, M.D. Trent Taylor, M.D. Professor Assistant Professor Nephrology Gastroenterology Montaser Shaheen, M.D. Elaine Thomas, M.D. Assistant Professor Professor Hematology/Oncology Infectious Diseases

Mark Sheldon, M.D. Karla Thornton, M.D., MPH Associate Professor Associate Professor Cardiology Infectious Diseases Wilmer Sibbitt, M.D. T. Craig Timm, M.D. Professor Professor Rheumatology Cardiology Anne Simpson, M.D. Alan Tomkinson, Ph.D. Professor Professsor Geriatrics Hematology/Oncology

231

Internal Medicine Faculty (Continued)

Dona Upson, M.D. Bronwyn Wilson, M.D., MPH Associate Professor Professor Pulmonary/Critical Care/Sleep Medicine General Medicine

Monica Delgado Vargas, Ph.D. Bryan Wood, M.D. Research Assistant Professor Assistant Professor Gastroenterology Hospital Medicine Reina Villareal, M.D. Anthony Worsham, M.D. Associate Professor Assistant Professor Endocrinology Hospital Medicine

Dennis Villareal, M.D. Terry Wu, Ph.D. Professor Research Assistant Professor Geriatrics Global Health

April Volk, M.D. Janice Yager, Ph.D. Assistant Professor Professor Gastroenterology Epidemiology Carolyn Voss, M.D. Hui Yang, Ph.D. Professor Research Assistant Professor General Medicine Hematology/Oncology Wyatt Voyles, M.D. Dongmei Ye, Ph.D. Associate Professor Research Assistant Professor Cardiology Gastroenterology Michael West, M.D. Ellen Yee, M.D., MPH Assistant Professor Professor Cardiology General Medicine

Charles Wiggins, Ph.D. Philip Zager, M.D. Associate Professor Professor Emeritus Epidemiology Nephrology

Steven Williams, M.D., MPH Eleana Zamora, M.D. Professor Assistant Professor Infectious Diseases Pulmonary/Critical Care/Sleep Medicine

232

INTERNAL MEDICINE FELLOWS 2011-2012

CARDIOLOGY Ihab Alomari, M.D. Vishal Goyal. M.D. Selby Oberton, M.D. First Year Fellow Second Year Fellow Third Year Fellow

Heather Baxter, M.D. Yasmin Hamirani, M.D. Allon Rafael, M.D. First Year Fellow Third Year Fellow First Year Fellow

Jon Blaschke, M.D. Carlos Macias-Argote, Alex Schevchuck, M.D. Second Year Fellow M.D. First Year Fellow Third Year Fellow

Nathan Boyer, M.D. Joshua Mozes, M.D. Saadi Siddiqi, M.D. Third Year Fellow Second Year Fellow Third Year Fellow

ENDOCRINOLOGY Christina Lovato, MD Rina Patel-Trujillo, DO Hung Phuoc Nguyen, Second Year Fellow First Year Fellow MD First Year Fellow

Corinn Sadler, MD Second Year Fellow

GASTROENTEROLOGY Ashwin Ashok, MD George Holman, MD Yen N. Quang, PharmD, Third Year Fellow First Year Fellow MD Second Year Fellow

Rodney Engel, MD Archana Kaza, MD Brian Story, MD Second Year Fellow Third Year Fellow Second Year Fellow

Sarita Gayle, MD Adam Mougey, MD Erich Vorlop, MD First Year Fellow Third Year Fellow Third Year Fellow

Laurel Hartwell, MD Leslie Price, MD Moustafa Youssef, MD First Year Fellow Second Year Fellow First Year Fellow

233

GERIATRICS Natavan Karimova, MD

HEMATOLOGY/ONCOLOGY Thomas Downs, MD Cristhiam Rojas Ankita Shah Patel, MD Hernandez, MD

Waheed Murad, MD

INFECTIOUS DISEASES Kingsley Asare, DO Firas Aswad, MD Luong Phu Nguyen, MD

Kari Yacisin, MD

NEPHROLOGY

Amandeep Chadha, David Mills, MD Amarpreet Sandhu, DO MD First Year Fellow First Year Fellow First Year Fellow

Rabeea Choudhary, Tudor Ocneanu, MD Deetu Simh, MD MD Second Year Fellow Second Year Fellow Second Year Fellow

David Chua, MD Carlos Reyes, MD Zhi (Ken) Xu, MD First Year Fellow Second Year Fellow Second Year Fellow

234

PULMONARY/CRITICAL CARE/SLEEP MEDICINE

Hassan Abouhouli, MD Pablo Garcia, MD Shahana Masood, MD Sleep Medicine Fellow Critical Care Fellow Sleep Medicine Fellow

Shozab Ahmed, MD Saman Hayatdouvdi, Chris Quintana, MD Critical Care Fellow MD Critical Care Fellow Pulmonary/Critical Care Fellow Jarrod Frizzell, MD Theresa Heynekamp, Deepak Taneja, MD Pulmonary/Critical Care MD Pulmonary/Critical Care Fellow Pulmonary/Critical Care Fellow

Fellow

RHEUMATOLOGY

Suzanne Emil, MD Hillary Norton, MD Leslie Sanchez- Junior Fellow Senior Fellow Goettler, MD Junior Fellow

235

Internal Medicine Housestaff 2011-2012

UNM Chief Resident VA Chief Resident VA Chief Resident-Primary Care

Alisha Parada, MD Leonardo Macias, MD Eva Angeli, MD Graduated from the Graduated from Graduated from the University of New Universidad University of New Mexico School of Autonoma de Baja Mexico School of Medicine California Medicine Completed Residency Completed Residency Completed Residency at UNM Department at UNM Department at UNM Department of Internal Medicine; completed of Internal Medicine of Internal Medicine; completed Primary Care and Integrative Primary Care Track. Medicine Tracks.

Housestaff – Program Year 1

Omar Abu Saleh, MD Jeramiah Bustos, MD Graduate of Jordan University of Science Jeramiah Bustos went to medical school at and Technology the University of New Mexico School of Medicine

Ahmad Allaham, MD Rory Carrera, MD Graduate of Jordan University of Science Rory Carrera went to medical school at the and Technology University of Utah

Sara Arguello, MD Leslie Colip, MD Sara Arguello went to medical school at Graduate of Temple University School of Tulane School of Medicine. Medicine

Nada Bader, MD Jerome Cordova, MD Graduate of University of Jordan Jerome Cordova went to medical school at the University of New Mexico

Michel Barakat, MD Wei Wei (Wendy) Dai, DO Michael M. Barakat went to medical school Wendy Dai went to medical school at at the University of Utah School of Texas College of Osteopathic Medicine. Medicine

Kristen Barrett, MD Alexander Davis, MD Kristen Barrett went to medical school at Alexander Davis went to medical school at Royal College of Surgeons in Ireland. the University of New Mexico School of Medicine.

236

Housestaff – Program Year 1 (Continued)

Erin FitzGerald, DO Amar Patel, MD Erin FitzGerald went to medical school at Graduate of University of New Mexico the University of New England College of School of Medicine Osteopathic Medicine.

Jason Fredriksen, MD Aaron Pierce, MD Jason Fredriksen went to medical school at Graduate of University of New Mexico the University of New Mexico School of School of Medicine Medicine.

Taylor Goot, MD Lindsey Riggin, MD University of Texas Medical School at Graduate of Tulane University School of Houston Medicine

Lucie Griffin, DO Luis Salayandia, MD Graduate of Des Moines University College Graduate of University of New Mexico of Osteopathic Medicine School of Medicine

Whitney Griffith, MD Michael Stucky, MD Graduate of Jagiellonian University Medical Graduate of University of Colorado Denver College (Poland) School of Medicine

Sergio Huerta, MD Lawrence Tafoya, MD Graduate of University of New Mexico Lawrence C. R. Tafoya went to medical School of Medicine school at the University of New Mexico School of Medicine.

Jacob Imber, MD Liviya Thoreson, DO Graduate of University of Kansas School of Graduate of Western University of Health Medicine Sciences College of Osteopathic Medicine of the Pacific.

Krysta Johnson-Martinez, MD Kristen Upchurch, MD Krysta Johnson-Martinez went to medical Graduate of Harvard Medical School. school at the University of New Mexico School of Medicine. Trisstin Maroney, MD Alfred Van Baak, MD Trisstin Maroney went to medical school at Alfred Andrew van Baak went to medical the University of New Mexico School of school at the Universidad de Sao Paulo, Medicine. Brazil.

Emily Newsom, MD Stewart Walther, MD Graduate of Tulane University School of Stewart Walther went to medical school at Medicine Texas Tech University Health Science Center.

Karen Niehaus, MD Karen L. Niehaus went to medical school at Wright State Boonshoft School of Medicine.

237

Housestaff – Program Year 2

Orwah M. Al-Khalili, MD Basmah Jalil, MD Orwah Al-Khalili went to medical school at Basmah A. Jalil went to medical school at the University of Jordan. Aga Khan University Pakistan.

Prajit Arora, MD Shawn C. Kelly, MD Prajit Arora went to medical school at Graduate of the University of Newcastle Government Medical College and Hospital, Chandigarh, India.

Nour Ass'ad, MD Khaldoon Khirfan, MD Nour Assad went to medical school at the Khaldoon Tareq Husni Khirfan went to University of Jordan. medical school at Jordan University of Science and Technology.

Anita Batra, MD Timothy S. Moore, MD Anita Batra went to medical school at the Tim Moore went to medical school at the University of Nevada School of Medicine. University of Colorado.

Jessica Belmonte, MD Carolina Ponce Orellana, MD Graduate of the University of Illinois Graduate of the Universidad Católica de College of Medicine. Santiago, Ecuador.

Joshua J. Crose, DO Aaron Price, MD Graduate of the Touro University College of Graduate of the University of New Mexico Osteopathic Medicine. School of Medicine.

Jonathan J. Danaraj, DO Natalie (Mariam) Salas, MD Jonathan Danaraj went to medical school at Mariam Salas went to medical school at Western University of Health Sciences. Dubai Medical College for Girls.

Nathaniel R. DeFelice, MD Kristen D. Simmons, MD Graduate of Ben-Gurion University of the Krissy Simmons went to medical school at Negev. Drexel University College of Medicine (formerly MCP Hahnemann).

Angela Dunn, DO Terry Pham Taylor, MD Graduate of the Texas College of Terry Taylor went to medical school at the Osteopathic Medicine, University of North University of Texas Medical Branch in Texas Health Science Center Galveston Texas.

Ala' Ebaid, MD Richard A. Vestal, MD Ala' Ebaid went to medical school at the Richard A. Vestal went to medical school at University of Jordan. the University of New Mexico School of Medicine. Jeffery D. Edwards, MD Graduate of the University of Texas Medical School at Houston.

238

Housestaff – Program Year 3

Emran Abu Atherah, MD LaWanda Jim, MD Emran Abu Atherah went to medical school Graduate of the University of New Mexico at the University of Jordan. School of Medicine.

Tarik Alhmoud, MD Morgan Lyons, DO Graduate of the University of Jordan. Morgan Lyons went to medical school at Arizona College of Osteopathic Medicine.

Munif Alkouz, MD Marc Montanaro, MD Graduate of the University of Jordan. Graduate of the Oregon Health Sciences University School of Medicine.

Romy Cabacungan, MD Muhammed Raza Naqvi, MD Romy Cabacungan Jr. went to medical Graduate of the Rawalpindi Medical school at Our Lady of Fatima College of College, Pakistan. Medicine, Philippines. Karen Cardon, MD Leigh Ann Neely, MD Karen Cardon went to medical school at the Leigh Ann F. Neely went to medical school University of New Mexico School of at the University of Colorado. Medicine.

Elizabeth (Sage) Colombo, MD Sonia Ponce, MD Graduate of the University of New Mexico Sonia G. Ponce went to medical school at School of Medicine. the University of Utah School of Medicine.

Star Fowler, DO Shalini Ravi-Kumar, MD Graduate of the Arizona College of Graduate of the Kilpauk Medical College, Osteopathic Medicine of Midwestern India. University. Mark Garcia, MD Patrick Rendon, MD Graduate of the University of New Mexico Graduate of the University of New Mexico School of Medicine. School of Medicine.

Ravneet Grewal, MD Bradley Rosen, DO Ravneet Grewal went to medical school at Graduate of the Michigan State University Government Medical College, Amritsar, College of Osteopathic Medicine. India. Mariam Hashimi, DO Seth Scott, MD Graduate of Touro College of Osteopathic Graduate of the University of Cincinnati Medicine. College of Medicine

Paul Hassett, DO Graduate of the Oklahoma State University College of Osteopathic Medicine.

239