Mycena Genomes Resolve the Evolution of Fungal Bioluminescence
Mycena genomes resolve the evolution of fungal bioluminescence Huei-Mien Kea,1, Hsin-Han Leea, Chan-Yi Ivy Lina,b, Yu-Ching Liua, Min R. Lua,c, Jo-Wei Allison Hsiehc,d, Chiung-Chih Changa,e, Pei-Hsuan Wuf, Meiyeh Jade Lua, Jeng-Yi Lia, Gaus Shangg, Rita Jui-Hsien Lud,h, László G. Nagyi,j, Pao-Yang Chenc,d, Hsiao-Wei Kaoe, and Isheng Jason Tsaia,c,1 aBiodiversity Research Center, Academia Sinica, Taipei 115, Taiwan; bDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520; cGenome and Systems Biology Degree Program, Academia Sinica and National Taiwan University, Taipei 106, Taiwan; dInstitute of Plant and Microbial Biology, Academia Sinica, Taipei 115, Taiwan; eDepartment of Life Sciences, National Chung Hsing University, Taichung 402, Taiwan; fMaster Program for Plant Medicine and Good Agricultural Practice, National Chung Hsing University, Taichung 402, Taiwan; gDepartment of Biotechnology, Ming Chuan University, Taoyuan 333, Taiwan; hDepartment of Medicine, Washington University in St. Louis, St. Louis, MO 63110; iSynthetic and Systems Biology Unit, Biological Research Centre, 6726 Szeged, Hungary; and jDepartment of Plant Anatomy, Institute of Biology, Eötvös Loránd University, Budapest, 1117 Hungary Edited by Manyuan Long, University of Chicago, Chicago, IL, and accepted by Editorial Board Member W. F. Doolittle October 28, 2020 (received for review May 27, 2020) Mushroom-forming fungi in the order Agaricales represent an in- fungi of three lineages: Armillaria, mycenoid, and Omphalotus dependent origin of bioluminescence in the tree of life; yet the (7). Phylogeny reconstruction suggested that luciferase origi- diversity, evolutionary history, and timing of the origin of fungal nated in early Agaricales.
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