Springer Journals Archives of Virology ~ Springerwiennewyork

SpringerJournals

Archives of Virology

Official Journal of the Virology Division of the International Union of Microbiological Societies

Editor in Chief: M. H. V. Van Regenmortel, Strasbourg Editorial Board: L. Enjuanes, Madrid T. Folks, Atlanta, GA T. K. Frey, Atlanta, GA R. A. Killington, Leeds H.-D. Klenk, Marburg E. P. Rybicki, Rondebosch E. G. Strauss, Pasadena, CA M. J. Studdert, Parkville M. Tashiro, Tokyo A. Vaheri, Helsinki Virology Division: M. A. Mayo, Dundee Special Issues Editors: C. H. Calisher, Fort Collins, CO G. Siegl, St. Gallen

Archives of Virology publishes original contributions from all branches of research on viruses, virus• like agents, and virus infections of humans, animals, plants, insects, and bacteria. Coverage includes the broadest spectrum of topics, from initial descriptions of newly discovered viruses, to studies of virus structure, composition, and genetics, to studies of virus interactions with host cells, host organ• isms, and host populations. Multidisciplinary studies are particularly welcome, as are studies employing molecular biologic, molec• ular genetics, and modern immunologic and epidemiologic approaches. For example, studies on the molecular pathogenesis, pathophysiology, and genetics of virus infections in individual hosts, and studies on the molecular epidemiology of virus infections in populations, are encouraged. Stud• ies involving applied research, such as diagnostic technology development, monoclonal antibody panel development, vaccine development, and antiviral drug development, are also encouraged. However, such studies are often better presented in the context of a specific application or as they bear upon general principles of interest to many virologists. In all cases, it is the quality of the re• search work, its significance, and its originality which will decide acceptability.

Subscription Information This journal is included in the program: "LINK - Springer Print Journals Go Electronic" ISSN 0304-8608 (print), ISSN 1432-8798 (electronic) ISSN (electronic edition): 1432-8798 2001. Vol. 146 (12 issues ). Title No. 705 DM 3910.-, ATS 27493.- plus carriage charges View table of contents and abstracts online at: approx. US $ 2,369.00 including carriage charges www.springer.at/archvirol

~ SpringerWienNewYork A·1201 Wien, Sachsenplatz 4-6, P.O. Box 89, Fax +43.1.330 24 26-62, e-mail: [email protected], Internet: www.springer.at D-69126 Heidelberg, Haberstraf3e 7, Fax +49.6221.345-229, e-mail: [email protected] USA, Secaucus, NJ 07096-2485, P.O. Box 2485. Fax +1.201.348-4505, e-mail: [email protected] Eastem Book Service. Japan, Tokyo 113, 3-13, Hongo 3-chome. Bunkyo-ku, Fax +81.3.38 180864, e-mail: [email protected] SpringerNews

Martin H. Groschup, Hans Kretzschmar (eds.)

Prion Diseases

Diagnosis and Pathogenesis

2000. IX, 290 pages. 89 partly coloured figures. Hardcover OM 250,-, 65 1750,• (recommended retail price) (Special edition of "Archives of Virology", Supplement 16) (50ft cover edition of Supplement 16 only available for subscribers of "Archives of Virology") ISBN 3-211-83S30-X

A comprehensive understanding of the biology of prion diseases is crucial for risk assess• ment as regards both humans and animals. To further the communication of the current knowledge and the exchange of diagnostic technologies in the scientific community, a symposium on the 'Characterization and Diagnosis of Prion Diseases' was held from Sep• tember 23-25, 1999 in TGbingen, Germany. The overwhelming interest and the participa• tion of more than 500 scientists from 26 countries made this symposium the largest meet• ing ever held in the field.

In this Supplementum to Archives of Virology twenty-six invited speakers comprehensively present their data on the pathogenesis of prion diseases in humans and animals, on mole• cular mechanisms involved in the transmissibility across species barriers, on animal and in• vitro models currently available for the detection and quantification of infectivity and on the characterization of prion strains. This selection attempts to reflect the current state of the art, but cannot possibly represent the whole spectrum of research in the prion field.

SpringerLifeSciences

~ SpringerWienNewYork A-1201 Wien, Sachsenplatz 4-6, P.O. Box 89, Fax +43.1.330 24 26, e-mail: [email protected]. Internet: www.springer.at D-69126 Heidelberg. HaberstraBe 7, Fax +49.6221.345-229, e-mail: [email protected] USA, Secaucus, NJ 07096-2485, P.O. Box 2485, Fax +1.201.348-4505, e-mail: [email protected] Eastern Book Service, Japan, Tokya 113, 3-13, Hongo 3-chome, Bunkyo-ku, Fax +81.3.38 18 08 64, e-mail: [email protected] SpringerLifeSciences

Charles H. Calisher, M. C. Horzinek (eds.)

100 Years of Virology The Birth and Growth of a Discipline

1999. VII, 220 pages. 75 figures. Hardcover OM 248,-, CiS 1736,• (recommended retail price) (Special edition of "Archives of Virology, Supplement 15") (Softcover edition of Suppl. 15 only available for subscribers to "Archives of Virology") ISBN 3-211-83384-6

One hundred years ago, when Martinus W. Beijerinck in Delft and Friedrich Loeffler on Riems Island discovered a new class of infectious agents in plants and animals, a new discipline was born. This book, a compilation of papers written by well-recognized scientists, gives an impression of the early days, the pioneer period and the current state of virology. Recent developments and future perspectives of this discipline are sketched against a historic background.

With contributions by A. Alcami, D. Baulcombe, F. Brown, L. W. Enquist, H. Feld• mann, A. Garcia-Sastre, D. Griffiths, M. C. Horzinek, A. van Kammen, H.-D. Klenk, F. A. Murphy, T. Muster, R. O'Neill, P. Palese, C. Patience, R. Rott, H.- P. Schmiede• bach, S. Schneider-Schau lies, G. L. Smith, J. A. Symons, Y. Takeuchi, V. ter Meulen, P. J. W. Venables, V. E. Volchkov, V. A. Volchkova, R. A. Weiss, W. Wittmann, H. Zheng

Please visit our website: www.springer.at

~ SpringerWienNewYork A-1201 Wien, Sachsenplatz 4-6, P.O.Box 89, Fax +43.1 .330 24 26, e-mail: [email protected], Internet: www.springer.at 0-69126 Heidelberg, HaberstraBe 7, Fax +49.6221.345-229, a-mail: [email protected] USA, Secaucus, NJ 07096-2485, P.O. Box 2485. Fax +1.201 .348-4505, e-mail: [email protected] Eastern Book Service, Japan, Tokyo 113, 3-13, Hongo 3-chome, Bunkyo-ku, Fax +81.3.38 180864, e-mail: [email protected] SpringerLifeSciences

Philip S. Mellor et al. (eds.)

African Horse Sickness

1998. VIII, 342 pages. 86 partly coloured figures. Hardcover DM 290,-, oS 2030,• (recommended retail price) (Special edition of "Archives of Virology, Supplement 14") (Softcover edition of Suppl. 14 only available for subscribers to "Archives of Virology") ISBN 3-211-83133-9

African horse sickness virus is a double-stranded RNA virus which causes a non-con• tagious, infectious arthropod-borne disease of equines and occasionally dogs. Nine distinct, internationally recognised serotypes of the virus have so far been identified. This book is based upon the findings of two programmes funded by the European Commission. It will be of value not only to the specialist research workers but also to veterinary workers dealing with control and to legislators seeking to promote safe international movement of equines. The topics covered include state-of-the-art dis• cussions on diagnostics, vaccines, molecular biology, vector studies, and epidemiology.

" ... This splendid and highly entertaining book gives a comprehensive account of the result obtained from those studies. Its contents are organised along disciplinary lines and are divided into sections dealing with epidemiology, entomology, molecular bi• ology, vaccines and diagnosis ... " The Veterinary Record

Please visit our website: www.springer.at

SpringerWienNewYork

A-1201 Wien. Sachsenplatz 4-6, P.O.Box 89, Fax +43.1.330 24 26, e-mail: [email protected], Internet: www.sprlnger.at D-69126 Heidelberg, Haberstral3e 7, Fax +49.6221.345-229, e-mail: [email protected] USA, Secaucus, NJ 07096-2485, P.O. Box 2485, Fax +1.201.348-4505, e-mail: [email protected] Eastern Book Service, Japan, Tokyo 113, 3-13. Hongo 3-charne, Bunkyo-ku, Fax +81.3.38 180864, e-mail: [email protected] Spnnger-Verlag and the Environment

WEAT SPRINGER-VERLAG FIRMLY BELIEVE THAT AN international science publisher has a special obliga• tion to the environment, and our corporate policies consistently reflect this conviction. WE ALSO EXPECT OUR BUSINESS PARTNERS- PRINTERS, paper mills, packaging manufacturers, etc. - to commit themselves to using environmentally friendly mate• rials and production processes. THE PAPERIN THIS BOOKIS MADE FROM NO-CHLORINE pulp and is acid free, in conformance with inter• national standards for paper permanency.