TMEM184B Antibody Cat. No.: 5683
TMEM184B Antibody
Immunohistochemistry of TMEM184B in human lung Immunofluorescence of TMEM184B in human lung tissue tissue with TMEM184B antibody at 5 μg/mL. with TMEM184B antibody at 20 μg/mL.
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine: (100%)
TMEM184B antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TMEM184B. IMMUNOGEN:
The immunogen is located within the last 50 amino acids of TMEM184B.
TESTED APPLICATIONS: ELISA, IF, IHC-P, WB
September 23, 2021 1 https://www.prosci-inc.com/tmem184b-antibody-5683.html TMEM184B antibody can be used for detection of TMEM184B by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. APPLICATIONS: Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
POSITIVE CONTROL: 1) Cat. No. 1462 - Rat Lung Tissue Lysate
2) Cat. No. 10-101 - Human Lung Tissue Slide
Properties
PURIFICATION: TMEM184B Antibody is affinity chromatography purified via peptide column.
CLONALITY: Polyclonal
ISOTYPE: IgG
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
BUFFER: TMEM184B Antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION: 1 mg/mL
TMEM184B antibody can be stored at 4˚C for three months and -20˚C, stable for up to STORAGE CONDITIONS: one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
OFFICIAL SYMBOL: TMEM184B
TMEM184B Antibody: FM08, HS5O6A, C22orf5, PSEC0108, Transmembrane protein 184B, ALTERNATE NAMES: Putative MAPK-activating protein FM08
ACCESSION NO.: NP_036396
PROTEIN GI NO.: 63259329
GENE ID: 25829
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
September 23, 2021 2 https://www.prosci-inc.com/tmem184b-antibody-5683.html TMEM184B Antibody: TMEM184B, also known as C22orf5, is a 407 amino acid multi-pass membrane protein and represents a novel gene in the activation of the MAPK signaling pathway. The gene encoding TMEM184B maps to human chromosome 22; mutations in BACKGROUND: several of the genes in chromosome 22 are involved in the development of autism, schizophrenia, Phelan-McDermid syndrome and Neurofibromatosis type 2, suggesting that TMEM184B may play a role in these syndromes.
1) Matsuda A, Suzuki Y, Honda G, et al. Large-scale identification and characterization of REFERENCES: human genes that activate NF-kappaB and MAPK signaling pathways. Oncogene2003; 22:3307-18.
2) Dunham I, Shimizu N, Roe BA, et al. The DNA sequence of human chromosome 2. Nature1999; 402:489-495.
ANTIBODIES FOR RESEARCH USE ONLY.
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September 23, 2021 3 https://www.prosci-inc.com/tmem184b-antibody-5683.html