TMEM184B Antibody (Pab)

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21.10.2014TMEM184B antibody (pAb) Rabbit Anti-Human/Mouse/Rat Transmembrane Protein 184B (C22orf5, HS5O6A, FM08, PSEC0108) Instruction Manual Catalog Number PK-AB718-5683 Synonyms TMEM184B Antibody: Transmembrane Protein 184B, C22orf5, HS5O6A, FM08, PSEC0108 Description TMEM184B, also known as C22orf5, is a 407 amino acid multi-pass membrane protein and represents a novel gene in the activation of the MAPK signaling pathway. The gene encoding TMEM184B maps to human chromosome 22; mutations in several of the genes in chromosome 22 are involved in the development of autism, schizophrenia, Phelan-McDermid syndrome and Neurofibromatosis type 2, suggesting that TMEM184B may play a role in these syndromes. Quantity 100 µg Source / Host Rabbit Immunogen TMEM184B antibody was raised against a 15 amino acid peptide near the carboxy terminus of human TMEM184B. Purification Method Affinity chromatography purified via peptide column. Clone / IgG Subtype Polyclonal antibody Species Reactivity Human, Mouse, Rat Specificity Formulation Antibody is supplied in PBS containing 0.02% sodium azide. Reconstitution During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Storage & Stability Antibody can be stored at 4ºC for three months and at -20°C for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. Applications E, WB, IHC, IF |Note: Antibody might be suitable for other applications not tested so far. Optimal concentrations for each application have to be determined indivudually. TMEM184B antibody can be used for detection of TMEM184B by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL. Images Available upon request. References Matsuda A, Suzuki Y, Honda G, et al. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. Oncogene 2003; 22:3307-18. Dunham I, Shimizu N, Roe BA, et al. The DNA sequence of human chromosome 2. Nature 1999; 402:489-495. Images Available upon request. Related Products Cat.No. PK-AB718-5683P - TMEM184B Peptide Cat. No. PK-AB718-1462 - Rat Lung Tissue Lysate FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC PROCEDURES. PromoCell GmbH North America 1 – 866 – 251 – 2860 (toll free) Email: [email protected] Sickingenstr. 63/65 Deutschland 0800 – 776 66 23 (gebührenfrei) www.promokine.info 69126 Heidelberg France 0800 90 93 32 (ligne verte) Germany United Kingdom 0800 – 96 03 33 (toll free) Other Countries +49 6221 – 649 34 0 09/2014 .

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Microrna Expression Signature of Oral Squamous Cell Carcinoma: Functional Role of Microrna-26A&Sol;B in the Modulation of No
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