Supplementary Table 1. Control system M1 and M2 significantly expressed involved in macrophage differentiation and polarization. M1 Name M2 Gene Name Entrez Gene ID Gene ID Interferon, gamma-inducible protein 16 3428 Cystinosis, nephropathic 1497

Hypothetical protein BC012330 116071 Protease, serine, 22 64063

Chemokine (C-C motif) ligand 2 6347 Niemann-Pick disease, type C1 4864

Poly (ADP-ribose) polymerase family, 83666 Phosphatidylinositol binding clathrin assembly 8301 member 9 protein Lipocalin-interacting membrane receptor 55716 Solute carrier family 38, member 6 145389

Epithelial stromal interaction 1 (breast) 94240 Homeobox C14 360030

2'-5'-oligoadenylate synthetase 3, 4940 Selenoprotein T 51714 100kDa Somatostatin receptor 2 6752 Angiopoietin-like 4 51129

Chemokine (C-X-C motif) ligand 16 58191 GRP1 (general receptor for phosphoinositides 160622 1)-associated scaffold protein GTPase, IMAP family member 8 155038 Nuclear receptor subfamily 4, group A, 8013 member 3 DR1-associated protein 1 (negative 10589 21 open reading frame 82 114036 2 alpha) Interferon-induced protein 44 10964 Oviductal 1, 120kDa (mucin 9, 5016 oviductin) PTK2B protein tyrosine kinase 2 beta 2185 Chromosome 9 open reading frame 150 286343

Hypothetical protein BC012317 93082 30 kDa protein 55831

N-acetylglucosamine kinase 55577 Growth arrest-specific 2 like 3 283431

TPR domain containing STI2 199223 Serine protease inhibitor, Kunitz type 1 6692

Phosphodiesterase 4D interacting 9659 FK506 binding protein 1A, 12kDa 2280 protein (myomegalin) Baculoviral IAP repeat-containing 2 329 SH3 and cysteine rich domain 2 342667

2'-5'-oligoadenylate synthetase 2, 4939 ATPase, Na+/K+ transporting, beta 3 483 69/71kDa polypeptide V-yes-1 Yamaguchi sarcoma viral 4067 Annexin A1 301 related oncogene homolog Ras homolog gene family, member G 391 Chromosome 12 open reading frame 5 57103 (rho G) Caspase recruitment domain family, 84674 VGF nerve growth factor inducible 7425 member 6 Solute carrier organic anion transporter 28232 Solute carrier family 6 (neurotransmitter 6539 family, member 3A1 transporter, betaine/GABA), member 12 Interleukin 1 receptor, type II 7850 Tissue inhibitor of metalloproteinase 4 7079

Solute carrier family 25, member 27 9481 CD1C antigen, c polypeptide 911

V-src sarcoma (Schmidt-Ruppin A-2) 6714 KIAA1919 91749 viral oncogene homolog (avian) 5,10-methenyltetrahydrofolate 10588 Synuclein, beta 6620 synthetase (5-formyltetrahydrofolate cyclo-) Ligand of numb-protein X 84708 Chromosome 20 open reading frame 139 140809

Discoidin domain receptor family, 4921 Transmembrane 7 superfamily member 1 7107 member 2 (upregulated in kidney) 2'-5'-oligoadenylate synthetase-like 8638 Translation factor sui1 homolog 10289

Hypothetical protein FLJ40722 285966 RCE1 homolog, prenyl protein protease (S. 9986 cerevisiae) Amyotrophic lateral sclerosis 4 23064 Solute carrier family 24 57419 (sodium/potassium/calcium exchanger), member 3 Normal mucosa of esophagus specific 1 84419 Sortilin-related VPS10 domain containing 114815 receptor 1 Ring finger protein (C3HC4 type) 159 84333 Dehydrogenase/reductase (SDR family) 51635 member 7 HEG homolog 57493 Interleukin 6 signal transducer (gp130, 3572 oncostatin M receptor) IBR domain containing 3 127544 Tumor necrosis factor receptor superfamily, 4982 member 11b (osteoprotegerin) Sialyltransferase 4B (beta-galactoside 6483 Stress-induced-phosphoprotein 1 10963 alpha-2,3-sialyltransferase) (Hsp70/Hsp90-organizing protein) CASP8 and FADD-like apoptosis 8837 NADPH oxidase organizer 1 124056 regulator Thyroid hormone receptor associated 9969 Epidermal growth factor receptor pathway 2059 protein 1 substrate 8 Chemokine (C-C motif) receptor 7 1236 Hypothetical protein FLJ20753 55036

Glutamine-fructose-6-phosphate 9945 Tubulin, alpha 8 51807 transaminase 2 Histone 1, H2aj 8331 Myosin VI 4646

Chemokine (C-C motif) ligand 1 6346 Aryl hydrocarbon receptor nuclear 406 translocator-like Solute carrier family 43, member 2 124935 Hemicentin 83872

Cancer/testis antigen 1B 1485 RAS p21 protein activator (GTPase activating 5921 protein) 1 Histone 1, H2bg 8339 Visual system homeobox 1 homolog, CHX10- 30813 like (zebrafish) Histone 3, H2a 92815 Hypothetical protein MGC19780 199857

Histone 1, H2bl 8340 Glutaminase 2744

Histone 1, H2be 8344 Solute carrier family 16 (monocarboxylic acid 9120 transporters), member 6 Histone 1, H2bn 8341 Prion protein (p27-30) 5621

TNFAIP3 interacting protein 1 10318 Phosphatidylinositol glycan, class W 284098

TNFAIP3 interacting protein 3 79931 Serine protease inhibitor, Kazal type 6 404203

Serine (or cysteine) proteinase inhibitor, 8710 Chromodomain helicase DNA binding protein 55636 clade B (ovalbumin), member 7 7 Interferon-induced protein with 3434 Syntaxin binding protein 1 6812 tetratricopeptide repeats 1 Tumor protein p53 inducible nuclear 58476 Diacylglycerol O-acyltransferase homolog 2 84649 protein 2 (mouse) Superoxide dismutase 2, mitochondrial 6648 Protein kinase C, alpha 5578

Ankyrin repeat and BTB (POZ) domain 80325 Retinol dehydrogenase 10 (all-trans) 157506 containing 1 Secretogranin III 29106 Hypothetical protein LOC151146 79134

Interferon regulatory factor 7 3665 Hypothetical protein LOC55924 55924

Persephin 5623 Biliverdin reductase B (flavin reductase 645 (NADPH)) Poly (ADP-ribose) polymerase family, 84875 KIAA0802 23255 member 10 F-box protein 32 114907 Protein phosphatase 1 (formerly 2C)-like 151742

SP140 nuclear body protein 11262 HIV-1 induced protein HIN-1 54726

Chromosome 1 open reading frame 38 9473 Methionyl-tRNA formyltransferase, 123263 mitochondrial Myosin regulatory light chain MRLC2 103910 Ubiquitin-like 3 5412

Serine dehydratase 10993 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 9188

KIAA1404 protein 57169 Phytoceramidase, alkaline 55331

Sidekick homolog 2 (chicken) 54549 ATP-binding cassette, sub-family G (WHITE), 9429 member 2 Rab geranylgeranyltransferase, alpha 5875 Glucose-fructose domain 54438 subunit containing 1 Tumor necrosis factor receptor 8764 Collagen, type VI, alpha 2 1292 superfamily, member 14 (herpes virus entry mediator) Regulatory factor X, 3 (influences HLA 5991 Chromosome 9 open reading frame 55 55667 class II expression) HORMA domain containing protein 84072 Acid phosphatase-like 2 92370

Hypothetical protein FLJ11286 55337 Collagen, type VI, alpha 1 1291

Hyperparathyroidism 2 (with jaw tumor) 79577 Germ cell associated 1 83445

KIAA1970 protein 124454 Adaptor-related protein complex 2, alpha 2 161 subunit GRIP1 associated protein 1 56850 Sialytransferase 7 30815

Vascular endothelial growth factor C 7424 Solute carrier family 27 (fatty acid 10999 transporter), member 4 RasGEF domain family, member 1B 153020 Protease, serine, 23 11098

Hypothetical protein FLJ32009 220001 Hypothetical protein PP1665 81544

Hypothetical protein LOC348094 348094 Adenosine monophosphate deaminase 2 271 (isoform L) Zinc finger, MYND domain containing 15 84225 Nestin 10763

Hypothetical protein FLJ39575 286006 Protein kinase C and casein kinase substrate 29763 in neurons 3 Tumor necrosis factor receptor 8792 Collomin 342035 superfamily, member 11a, activator of NFKB ADP-ribosylation factor-like 8 221079 Chromodomain helicase DNA binding protein 80205 9 Acyl-Coenzyme A binding domain 91452 Hypothetical protein FLJ32954 151393 containing 5 Pellino homolog 1 (Drosophila) 57162 Adrenergic, alpha-1B-, receptor 147

Brain abundant, membrane attached 10409 Carbonyl reductase 3 874 signal protein 1 IQ motif containing GTPase activating 10788 Transmembrane 4 superfamily member 2 7102 protein 2 Hypothetical protein MGC4655 84752 ATP-binding cassette, sub-family B 5244 (MDR/TAP), member 4 KIAA1463 protein 57609 Solute carrier family 20 (phosphate 6575 transporter), member 2 Thyroid hormone receptor interactor 12 9320 KIAA0690 23223

Tight junction protein 1 (zona occludens 7082 Four and a half LIM domains 3 2275 1) Signal transducer and activator of 6774 Zinc finger CCCH type domain containing 8 84524 transcription 3 (acute-phase response factor) Chemokine (C-X-C motif) ligand 14 9547 Parathyroid hormone-like hormone 5744

Mannosidase, beta A, lysosomal 4126 Pleckstrin homology domain containing, 79156 family F (with FYVE domain) member 1 Hypothetical protein DKFZp761A052 55593 Mitochondrial ribosomal protein S6 64968

RAB43, member RAS oncogene family 339122 Diencephalon/mesencephalon homeobox 1 127343

Chromosome 9 open reading frame 95 54981 Six transmembrane epithelial antigen of the 26872 prostate ERO1-like beta (S. cerevisiae) 56605 Antigen p97 (melanoma associated) 4241

Myosin regulatory light chain MRCL3 10627 Plexin domain containing 2 84898

Butyrophilin, subfamily 2, member A3 54718 Integrin, alpha M (CD11b) 3684

Sialyltransferase 8D (alpha-2, 8- 7903 Tryptophan 2,3-dioxygenase 6999 polysialyltransferase) Cathepsin S 1520 Adenosine A3 receptor 140

FOS-like antigen 2 2355 Mitochondrial tumor suppressor 1 57509

General transcription factor IIF, 2962 Tumor necrosis factor receptor superfamily, 27242 polypeptide 1, 74kDa member 21 GCIP-interacting protein p29 25949 Chromosome 20 open reading frame 32 57091

Hypothetical protein LOC283680 283680 Hypothetical protein MGC34732 220047 Hypothetical protein MGC35194 93190 Hypothetical protein MGC40397 121053

Chemokine (C-C motif) ligand 5 6352 Peroxisome proliferative activated receptor, 5468 gamma Glucosamine (N-acetyl)-6-sulfatase 2799 FCH domain only 1 23149 (Sanfilippo disease IIID) Hypothetical protein LOC285216 285216 Abhydrolase domain containing 6 57406

Chromosome 10 open reading frame 70 55847 Mitochondrial folate transporter/carrier 81034

Hypothetical protein FLJ32833 148545 Chromosome 6 open reading frame 54 26236

Mdm4, transformed 3T3 cell double 4194 Prostate cancer associated protein 6 85414 minute 4, p53 binding protein (mouse) Transient receptor potential cation 51393 Protein tyrosine phosphatase, non-receptor 5784 channel, subfamily V, member 2 type 14 Fukutin related protein 79147 N-acetyltransferase 5 (ARD1 homolog, S. 51126 cerevisiae) Hypothetical protein BC004921 93349 Inositol polyphosphate-1-phosphatase 3628

Hepatitis A virus cellular receptor 1 26762 KIAA1394 protein 57571

Chromosome 6 open reading frame 145 221749 Excision repair cross-complementing rodent 2067 repair deficiency Zinc finger protein 407 55628 Porcupine homolog (Drosophila) 64840

CREB binding protein (Rubinstein-Taybi 1387 MAP1 light chain 3-like protein 2 440738 syndrome) Beta-2-microglobulin 567 Carboxypeptidase E 1363

FXYD domain containing ion transport 486 Adaptor-related protein complex 3, beta 2 8120 regulator 2 subunit Tryptophanyl-tRNA synthetase 7453 Potassium voltage-gated channel, subfamily 81033 H (eag-related), member 6 Similar to KIAA0592 protein 387680 Gametogenetin 199720

Ca2+dependent activator protein for 93664 Hypothetical protein MGC45871 359845 secretion 2 Lin-10 protein homolog 80262 Solute carrier family 16 (monocarboxylic acid 6567 transporters), member 2 LIM domain only 4 8543 Uncharacterized hypothalamus protein HT008 55852

Cyclin L1 57018 Discoidin, CUB and LCCL domain containing 131566 2 RAB2B, member RAS oncogene family 84932 Potassium channel modulatory factor 1 56888

Bromodomain containing 2 6046 Apical protein 2 134549

Spermatogenesis associated 5-like 1 79029 Amyloid beta (A4) precursor protein-binding, 54518 family B, member 1 interacting protein Myelin basic protein 4155 Hypothetical protein MGC16279 85002

Ubiquitin specific protease 18 11274 Dedicator of cytokinesis 3 1795

Zinc finger CCCH type domain 64761 Serine (or cysteine) proteinase inhibitor, clade 6318 containing 1 B (ovalbumin), member 4 SNF7 domain containing 2 51510 Serine (or cysteine) proteinase inhibitor, clade 6317 B (ovalbumin), member 3 Interferon-induced protein with 3437 Matrix metalloproteinase 12 (macrophage 4321 tetratricopeptide repeats 3 elastase) Kallikrein 10 5655 KIAA0040 gene product 9674

Lysosomal-associated membrane 27074 Aldehyde dehydrogenase 1 family, member 8854 protein 3 A2 Nuclear receptor coactivator 7 135112 Tudor domain containing 9 122402

Hypothetical protein FLJ31033 91351 Peroxisome proliferative activated receptor, 133522 gamma, coactivator 1, beta Interferon induced with helicase C 64135 Dishevelled associated activator of 23002 domain 1 morphogenesis 1 TERF1 (TRF1)-interacting nuclear factor 26277 RNA binding motif, single stranded interacting 5937 2 protein 1 Arginine-glutamic acid dipeptide (RE) 473 Fc fragment of IgG, low affinity IIb, receptor 2213 repeats for (CD32) EH-domain containing 4 30844 KIAA0859 51603

Adult retina protein 153222 Suppressor of cytokine signaling 1 8651

Interferon-induced protein with 24138 KIAA0701 protein 23074 tetratricopeptide repeats 5 Interferon, alpha-inducible protein (clone 9636 Follistatin 10468 IFI-15K) Ankyrin repeat and sterile alpha motif 23294 Mitogen-inducible gene 6 54206 domain containing 1 Caspase 3, apoptosis-related cysteine 836 Rhomboid, veinlet-like 4 (Drosophila) 162494 protease Kelch-like 6 (Drosophila) 89857 Pyruvate dehydrogenase phosphatase 57546 isoenzyme 2 Zinc finger, DHHC domain containing 17 23390 Non imprinted in Prader-Willi/Angelman 123606 syndrome 1 Cathepsin O 1519 Thrombospondin, type I, domain containing 2 84870

Purinergic receptor P2X, ligand-gated 5027 Mitogen-activated protein kinase 1 5594 ion channel, 7 Nuclear receptor subfamily 2, group C, 7182 Male sterility domain containing 1 55711 member 2 Sp3 transcription factor 6670 Chromosome 6 open reading frame 114 85411

Transcription factor SMIF 55802 Chromosome 21 open reading frame 13 150082

KIAA1033 protein 23325 Chromosome 10 open reading frame 22 84890

Arrestin domain containing 3 57561 Single stranded DNA binding protein 3 23648

APG12 autophagy 12-like (S. 9140 Insulin receptor substrate 1 3667 cerevisiae) Major vault protein 9961 Hypothetical protein FLJ31052 127943

Apolipoprotein L, 2 23780 Caspase recruitment domain family, member 29775 10 Ubiquitin protein ligase E3 component n- 197131 Fibronectin 1 2335 recognin 1 C-type (calcium dependent, 9976 Solute carrier family 5 (inositol transporters), 6526 carbohydrate-recognition domain) lectin, member 3 superfamily member 2 Cylindromatosis (turban tumor 1540 Secretogranin II (chromogranin C) 7857 syndrome) Ubiquitin specific protease 11 8237 Solute carrier family 30 (zinc transporter), 7781 member 3 Ubiquitin specific protease 15 9958 Cystathionase (cystathionine gamma-) 1491

Transcription factor 4 6925 ATP binding cassette gene, sub-family A 154664 (ABC1), member 13 SH3-domain binding protein 5 (BTK- 9467 Glioma-associated oncogene homolog (zinc 2735 associated) finger protein) Runt-related transcription factor 3 864 Hypothetical protein FLJ20533 54968

Estrogen receptor 1 2099 Cytoplasmic FMR1 interacting protein 2 26999

Endothelial cell growth factor 1 (platelet- 1890 Rai-like protein 399694 derived) Glutamate receptor, ionotropic, kainate 2898 Dystrobrevin, alpha 1837 2 Microfibrillar associated protein 5 8076 Oxidised low density lipoprotein (lectin-like) 4973 receptor 1 Blood vessel epicardial substance 11149 Spectrin, alpha, non-erythrocytic 1 (alpha- 6709 fodrin) Fatty acid binding protein 6, ileal 2172 Hypothetical protein FLJ20244 55621 (gastrotropin) mutarotase (aldose 1- 130589 Solute carrier family 26, member 4 5172 epimerase) Telomerase-associated protein 1 7011 E2F transcription factor 5, p130-binding 1875

Carbonic anhydrase XII 771 Ras homolog gene family, member F (in 54509 filopodia) Nuclear factor (erythroid-derived 2)-like 4779 Transmembrane 4 superfamily member 17 26262 1 Hypothetical gene CG012 116829 Hypothetical LOC401588 401588

KIAA0226 gene product 9711 Myoglobin 4151

Thymosin, beta 10 9168 Insulin-like growth factor binding protein 5 3488

Myosin IA 4640 Tripartite motif-containing 54 57159

Hypothetical protein LOC155036 155036 A disintegrin-like and metalloprotease 9510 (reprolysin type) with thrombospondin type 1 motif, 1 Platelet-derived growth factor receptor- 5157 Nicalin homolog (zebrefish) 56926 like Forkhead box F1 2294 CD209 antigen-like 10332

Hypothetical protein FLJ13855 65264 KIAA0090 protein 23065

T-box 3 (ulnar mammary syndrome) 6926 M-phase phosphoprotein 6 10200

RAB8A, member RAS oncogene family 4218 Fatty acid 2-hydroxylase 79152 DNA-damage-inducible transcript 3 1649 Cortactin binding protein 2 83992

Poliovirus receptor-related 2 5819 Similar to microtubule associated testis 375449 (herpesvirus entry mediator B) specific serine/threonine protein kinase BCL2-antagonist/killer 1 578 Dual specificity phosphatase 13 51207

PC2 (positive cofactor 2, multiprotein 51586 Protease, serine, 15 9361 complex) glutamine/Q-rich-associated protein Transcription factor EC 22797 Phosphatidic acid phosphatase type 2B 8613

Chromosome 6 open reading frame 62 81688 CD209 antigen 30835

Chromosome 16 open reading frame 7 9605 A disintegrin-like and metalloprotease 11096 (reprolysin type) with thrombospondin type 1 motif, 5 Cytochrome P450, family 11, subfamily 1584 Stimulated by retinoic acid gene 6 64220 B, polypeptide 1 Pleckstrin homology, Sec7 and coiled- 9267 RAS-related on chromosome 22 10633 coil domains 1(cytohesin 1) Egl nine homolog 3 (C. elegans) 112399 Copine VI (neuronal) 9362

Endothelin receptor type B 1910 Sortilin 1 6272

Regulator of G-protein signalling 20 8601 Deoxyribonuclease I-like 3 1776

Ureidopropionase, beta 51733 Paraneoplastic antigen 30850

SH2 domain containing phosphatase 79368 Transmembrane 4 superfamily member 12 23554 anchor protein 1 GLI-Kruppel family member GLI3 (Greig 2737 Factor for adipocyte differentiation 158 84230 cephalopolysyndactyly syndrome) GTPase, IMAP family member 4 55303 Cytokine inducible SH2-containing protein 1154

Fer-1-like 3, myoferlin (C. elegans) 26509 Adenylate kinase 5 26289

Myosin X 4651 Src-like-adaptor 6503

Plexin A2 5362 Potassium channel, subfamily K, member 6 9424

Hypothetical protein MGC8902 284565 Quiescin Q6 5768

Hypothetical protein LOC200030 200030 Basic leucine zipper transcription factor, ATF- 10538 like Hypothetical protein DJ328E19.C1.1 25832 Chromosome 6 open reading frame 60 79632

Glycophorin C (Gerbich blood group) 2995 Hypothetical protein FLJ25555 124930

Synaptic vesicle glycoprotein 2B 9899 T-cell acute lymphocytic leukemia 1 6886

Fasciculation and elongation protein 9638 Inhibin, beta E 83729 zeta 1 (zygin I) KIAA1598 57698 Lysyl oxidase 4015

Spectrin repeat containing, nuclear 23345 Protein phosphatase 1, regulatory (inhibitor) 94274 envelope 1 subunit 14A Mediator of RNA polymerase II 116931 Hypothetical protein MGC4172 79154 transcription, subunit 12 homolog (yeast)-like Protein tyrosine phosphatase, receptor 8499 T-cell activation leucine repeat-rich protein 23507 type, f polypeptide (PTPRF) SMAD specific E3 ubiquitin protein 64750 Meis1, myeloid ecotropic viral integration site 4212 ligase 2 1 homolog 2 (mouse) Response gene to complement 32 28984 G protein-coupled receptor kinase interactor 1 28964

Syntaxin 6 10228 Chemokine (C-C motif) ligand 17 6361

Amyloid beta (A4) precursor protein- 10307 Chromosome 2 open reading frame 23 65055 binding, family B, member 3 Hypothetical protein FLJ20647 55013 Arrestin domain containing 4 91947

Hypothetical protein DKFZp547L112 81787 Chemokine (C-C motif) ligand 26 10344

Ring finger protein 135 84282 Chromosome 14 open reading frame 58 55640

Hypothetical protein MGC16121 84848 Neurotrophic tyrosine kinase, receptor, type 1 4914

Protein C (inactivator of coagulation 5624 Cyclic nucleotide gated channel alpha 1 1259 factors Va and VIIIa) Zinc finger protein 533 151126 Wingless-type MMTV integration site family, 7471 member 1 GRINL1A complex upstream protein 145781 Carbohydrate kinase-like 23729

RGM domain family, member B 285705 Transient receptor potential cation channel, 7442 subfamily V, member 1 Vanin 1 8876 Mitogen-activated protein kinase-activated 7867 protein kinase 3 BTB and CNC homology 1, basic 60468 Myozenin 2 51778 leucine zipper transcription factor 2 G protein-coupled receptor 77 27202 Cholesterol 25-hydroxylase 9023

Hypothetical protein MGC10986 80774 Ataxin 1 6310

Chromosome 14 open reading frame 4 64207 Hypothetical protein MGC22014 200424

Snail homolog 2 (Drosophila) 6591 Monocyte to macrophage differentiation- 23531 associated Regucalcin (senescence marker protein- 9104 Cysteinyl leukotriene receptor 1 10800 30) Spermatogenesis associated 13 221178 Chromosome 5 open reading frame 18 7905

Solute carrier family 9 (sodium/hydrogen 285195 Plastin 1 (I isoform) 5357 exchanger), isoform 9 Prostaglandin E receptor 4 (subtype 5734 Sialyltransferase 1 (beta-galactoside alpha- 6480 EP4) 2,6-sialyltransferase) Intersectin 1 (SH3 domain protein) 6453 Homer homolog 2 (Drosophila) 9455

Leucine rich repeat containing 25 126364 Pericentriolar material 1 5108

Interleukin-1 receptor-associated kinase 3656 Rab9 effector p40 10244 2 Dual specificity phosphatase 10 11221 Succinate receptor 1 56670

Von Hippel-Lindau tumor suppressor 7428 Cathepsin C 1075

Zinc finger protein 462 58499 Six transmembrane epithelial antigen of 261729 prostate 2 Membrane protein, palmitoylated 5 64398 Adenylate cyclase 1 (brain) 107 (MAGUK p55 subfamily member 5) C-mir, cellular modulator of immune 220972 Fibrinogen-like 1 2267 recognition Chemokine (C-X-C motif) ligand 5 6374 CDK5 regulatory subunit associated protein 2 55755

Visinin-like 1 7447 FLJ00332 protein 374403

Hypothetical protein AE2 84224 Potassium channel, subfamily K, member 12 56660

V-erb-a erythroblastic leukemia viral 2066 Hypothetical protein FLJ31166 120939 oncogene homolog 4 (avian) Dynein, axonemal, heavy polypeptide 7 56171 Hypothetical protein A-211C6.1 57149

SWAP-70 protein 23075 B/K protein 51760

Mitogen-activated protein kinase kinase 4217 Junctophilin 1 56704 kinase 5 Thrombospondin 1 7057 CD1B antigen, b polypeptide 910

CD14 antigen 929

Hypothetical protein FLJ14525 84886

Phosphodiesterase 8B 8622

Histone deacetylase 7A 51564

Bradykinin receptor B2 624

Solute carrier family 5 (sodium/glucose 6524 cotransporter), member 2 Chemokine orphan receptor 1 57007

EH-domain containing 1 10938

Myristoylated alanine-rich protein kinase 4082 C substrate Trichorhinophalangeal syndrome I 7227

Notch homolog 2 (Drosophila) N- 388677 terminal like Yippee-like 3 (Drosophila) 83719

Hypothetical protein LOC196394 196394

Rabconnectin-3 23312

TANK-binding kinase 1 29110 Oxidation resistance 1 55074

Prostaglandin-endoperoxide synthase 2 5743

RAB6 interacting protein 1 23258

Sarcospan (Kras oncogene-associated 8082 gene) AT-binding transcription factor 1 463

IBR domain containing 2 255488

5-hydroxytryptamine (serotonin) 3357 receptor 2B G protein-coupled receptor 43 2867

Sema domain, transmembrane domain 80031 (TM), and cytoplasmic domain MCF.2 cell line derived transforming 4168 sequence Nucleotide-binding oligomerization 84166 domains 27 Hypothetical gene CG018 90634

A disintegrin-like and metalloprotease 9508 (reprolysin type) with thrombospondin type 1 motif, 3 CAP, adenylate cyclase-associated 10486 protein, 2 (yeast) Hypothetical protein FLJ31818 154743

Signal transducer and activator of 6775 transcription 4 DRE1 protein 54800

GTP cyclohydrolase 1 (dopa-responsive 2643 dystonia) Wilms tumor 1 associated protein 9589

Hypothetical protein FLJ11259 55332

Zonadhesin 7455

Prostaglandin I2 (prostacyclin) receptor 5739 (IP) Pleiomorphic adenoma gene 1 5324

Microtubule-associated protein 1 light 84557 chain 3 alpha NK3 transcription factor related, 1 4824 (Drosophila) Guanylate binding protein 5 115362

Matrix metalloproteinase 23B 8510 Notch homolog 4 (Drosophila) 4855

Frizzled homolog 4 (Drosophila) 8322

Tumor necrosis factor, alpha-induced 7127 protein 2 Sterile alpha motif domain containing 9 54809

Phospholipid scramblase 1 5359

Guanylate binding protein 2, interferon- 2634 inducible TNFRSF1A-associated via death 8717 domain Signal transducer and activator of 6772 transcription 1, 91kDa Tripartite motif-containing 21 6737

Ubiquitin D 10537

Bone marrow stromal cell antigen 2 684

EPH receptor B2 2048

Ankyrin repeat and FYVE domain 51479 containing 1 MHC class I polypeptide-related 4277 sequence B Ets variant gene 7 (TEL2 oncogene) 51513

P300/CBP-associated factor 8850

Nuclear antigen Sp100 6672

Pleckstrin homology domain containing, 57664 family A XIAP associated factor-1 54739

Myxovirus (influenza virus) resistance 2 4600 (mouse) Lectin, galactoside-binding, soluble, 8 3964 (galectin 8) Chromosome 21 open reading frame 91 54149

Hect domain and RLD 5 51191

Hypothetical protein LOC134285 134285

5-azacytidine induced 2 64343

Peroxisomal biogenesis factor 5-like 51555

Glutamate receptor interacting protein 2 80852

Chemokine (C-C motif) ligand 19 6363 KIAA0408 9729

Leucine rich repeat containing 3B 116135

Killer cell immunoglobulin-like receptor, 3805 two domains, long cytoplasmic tail, 4 Zinc finger CCCH type, antiviral 1 56829

Family with sequence similarity 8, 51439 member A1 5'-3' exoribonuclease 1 54464

Polyribonucleotide 87178 nucleotidyltransferase 1 Transglutaminase 1 (K polypeptide 7051 epidermal type I, protein-glutamine- gamma-glutamyltransferase) Calcium/calmodulin-dependent serine 8573 protein kinase (MAGUK family) GTP binding protein 1 9567

F-box protein 6 26270

T-cell activation GTPase activating 117289 protein Phosphodiesterase 4B, cAMP-specific 5142 (phosphodiesterase E4 dunce homolog, Drosophila) Phospholipase A2-activating protein 9373

Syntaxin 17 55014

Serine (or cysteine) proteinase inhibitor, 710 clade G (C1 inhibitor), member 1 Promyelocytic leukemia 5371

Activated Cdc42-associated kinase 1 10188

RAB24, member RAS oncogene family 53917

Chromosome 20 open reading frame 18 10616

Mov10, Moloney leukemia virus 10, 4343 homolog (mouse) Ras homolog enriched in brain like 1 121268

Homolog of yeast Sfi1 9814

Complement component 1, q 713 subcomponent, beta polypeptide Hypothetical protein MGC5566 79015

Similar to RIKEN cDNA 1810038N08 375346 gene Similar to Taxol resistant associated 389903 protein 3 (TRAG-3) CSAG family, member 2 9598

Chondrosarcoma associated gene 1 158511

Glypican 5 2262

CD69 antigen (p60, early T-cell 969 activation antigen) P8 protein (candidate of metastasis 1) 26471

Naked cuticle homolog 1 (Drosophila) 85407

HLA complex P5 10866

Hypothetical protein BC017868 159091

Testis expressed sequence 14 56155

Guanylate binding protein 4 115361

Guanylate binding protein 3 2635

Butyrophilin, subfamily 3, member A3 10384

Apolipoprotein B mRNA editing , 60489 catalytic polypeptide-like 3G 28kD interferon responsive protein 64108

Secreted and transmembrane 1 6398

Apolipoprotein L, 6 80830

Hypothetical protein LOC129607 129607

Guanine nucleotide binding protein (G 59345 protein), beta polypeptide 4 Tripartite motif-containing 5 85363

Hypothetical protein DKFZp761G058 152926

Zinc finger protein 101 94039

Core 1 UDP-galactose:N- 56913 acetylgalactosamine-alpha-R beta 1,3- RAR-related orphan receptor B 6096

Protein phosphatase 1, regulatory 5507 (inhibitor) subunit 3C Hypothetical protein FLJ20581 54988

Interferon induced transmembrane 8519 protein 1 (9-27) Solute carrier family 25, member 28 81894

Hypothetical protein FLJ12650 79570 FXYD domain containing ion transport 53826 regulator 6 Butyrophilin, subfamily 3, member A1 11119

Tripartite motif-containing 25 7706

5'-nucleotidase, cytosolic III 51251

Lymphocyte-activation gene 3 3902

Inter-alpha (globulin) inhibitor H4 3700 (plasma Kallikrein-sensitive glycoprotein) NEDD8 ultimate buster-1 51667

Hyaluronan and proteoglycan link 145864 protein 3 Apolipoprotein L, 1 8542

Proteasome (prosome, macropain) 5685 subunit, alpha type, 4 Hypothetical protein HSPC117 51493

Egf-like module containing, mucin-like, 2015 hormone receptor-like 1 Interferon induced transmembrane 10410 protein 3 (1-8U) Phorbol-12-myristate-13-acetate- 5366 induced protein 1 Retinoic acid receptor responder 5920 (tazarotene induced) 3 G protein-coupled receptor 155 151556

RNA binding motif protein 11 54033

Zinc finger protein (C2H2 type) 277 11179

Killer cell immunoglobulin-like receptor, 3803 two domains, long cytoplasmic tail, 2 Claudin 23 137075

Hypothetical protein FLJ12806 64853

Nijmegen breakage syndrome 1 (nibrin) 4683

Cytoplasmic polyadenylation element 22849 binding protein 3 Metallothionein 1J 4498

Interferon-induced protein 44 10964

Sialoadhesin 6614

Likely ortholog of mouse D11lgp2 79132

SP110 nuclear body protein 3431 Hypothetical protein FLJ23375 80021

Indoleamine-pyrrole 2,3 dioxygenase 3620

KIAA1618 57714

Protein kinase, interferon-inducible 5610 double stranded RNA dependent Interferon-induced protein 35 3430

DEAD (Asp-Glu-Ala-Asp) box 23586 polypeptide 58 Deltex 3-like (Drosophila) 151636

Hypothetical protein FLJ20035 55601

Caspase 5, apoptosis-related cysteine 838 protease Chemokine (C-X-C motif) ligand 11 6373

Interleukin 6 (interferon, beta 2) 3569

Polycystic kidney disease 2-like 1 9033

ATX1 antioxidant protein 1 homolog 475 (yeast) Chromosome 17 open reading frame 27 57674

Similar to PMS4 homolog mismatch 57639 repair protein - human Chromosome 9 open reading frame 91 203197

Tripartite motif-containing 56 81844

Interleukin 15 3600

Basic leucine zipper nuclear factor 1 8548 (JEM-1) G protein-coupled receptor 42 2866

Histone 1, H3c 8352

Complement factor H-related 1 3078

Immunoglobulin superfamily, member 8 93185

Pim-2 oncogene 11040

Interleukin 23, alpha subunit p19 51561

Hypothetical protein LOC283551 283551

Poly (ADP-ribose) polymerase family, 54625 member 14 Interferon-induced protein with 3433 tetratricopeptide repeats 2 Radical S-adenosyl methionine domain 91543 containing 2 Lectin, galactoside-binding, soluble, 3 3959 binding protein Tripartite motif-containing 22 10346

Unc-93 homolog B1 (C. elegans) 81622

Signal transducer and activator of 6773 transcription 2, 113kDa CD80 antigen (CD28 antigen ligand 1, 941 B7-1 antigen) DNA polymerase-transactivated protein 26010 6 Tripartite motif-containing 6 and tripartite 53840 motif-containing 34 Chromosome 21 open reading frame 42 54072

Interferon regulatory factor 1 3659

Peroxisomal proliferator-activated 85441 receptor A interacting complex 285 SRY (sex determining region Y)-box 5 6660

Leucine aminopeptidase 3 51056

GPI deacylase 80055

Catenin, beta like 1 56259

Hairy and enhancer of split 4 57801 (Drosophila) Proline dehydrogenase (oxidase) 1 5625

Ring finger protein 36 140691

Peptide YY 5697

Hypothetical protein FLJ11000 55281

Myeloid differentiation primary response 4615 gene (88) KIAA0082 23070

Major histocompatibility complex, class 3134 I, F Complement component 2 717

Apolipoprotein L, 3 80833

Otoferlin 9381

NAD kinase 65220

Major histocompatibility complex, class 3105 I, A Major histocompatibility complex, class 3106 I, B Hedgehog interacting protein 64399

Spermatogenesis associated, serine- 221409 rich 1 BCL2-like 13 (apoptosis facilitator) 23786

Interferon, alpha-inducible protein 27 3429

Major histocompatibility complex, class 3107 I, C Opioid growth factor receptor 11054

T-complex-associated-testis-expressed 6993 1-like 1 Major histocompatibility complex, class 3133 I, E Guanylate binding protein 1, interferon- 2633 inducible, 67kDa Bone morphogenetic protein receptor, 659 type II (serine/threonine kinase) Sorting nexin 6 58533

Type 1 tumor necrosis factor receptor 51752 shedding aminopeptidase regulator FLJ45422 protein 441140

Tripartite motif-containing 38 10475

ADP-ribosylhydrolase like 2 54936

Guanosine monophosphate reductase 2766

Hypothetical protein LOC147645 147645

Leukemia inhibitory factor receptor 3977

Lymphocyte antigen 6 complex, locus E 4061

GTP binding protein 2 54676

Fms-related tyrosine kinase 3 ligand 2323

B-factor, properdin 629

Melanoma antigen, family A, 12 4111

Hypothetical protein LOC126755 126755

Somatostatin receptor 5 6755

Creatine kinase, brain 1152

Leucyl/cystinyl aminopeptidase 4012 ADP-ribosylarginine 141

J-type co-chaperone HSC20 150274

Hypothetical protein LOC256021 256021

Transmembrane protein 16C 63982

G protein-coupled receptor, family C, 51704 group 5, member B Colony stimulating factor 2 (granulocyte- 1437 macrophage) Torsin family 1, member B (torsin B) 27348

Platelet-activating factor receptor 5724

Chemokine (C-C motif) receptor-like 1 51554

Sterol O-acyltransferase (acyl- 6646 Coenzyme A: cholesterol acyltransferase) 1 Mitofusin 1 55669

ADP-ribosylation factor-like 10C 55207

Fibroblast growth factor 13 2258

Solute carrier family 4, sodium 8671 bicarbonate cotransporter, member 4 Mitogen-activated protein kinase 10 5602

Myelin associated glycoprotein 4099

ERO1-like (S. cerevisiae) 30001

Ankyrin repeat domain 1 (cardiac 27063 muscle) Hypothetical protein FLJ25421 150350

Histone 2, H4 8370

Histone 1, H4f 8361

Histone 1, H4i 8294

Histone 1, H4h 8365

Histone 1, H2ak 8330

Acetylcholinesterase (YT blood group) 43

Zinc finger, SWIM domain containing 5 57643

Acid phosphatase 5, tartrate resistant 54

Caspase 4, apoptosis-related cysteine 837 protease Protein kinase (cAMP-dependent, 11142 catalytic) inhibitor gamma Hypothetical protein FLJ10808 55236

Sorting nexin 7 51375

FLJ39739 protein 388685

Interleukin 17 receptor D 54756

Hypothetical protein MGC20470 143630

CD47 antigen (Rh-related antigen, 961 integrin-associated signal transducer) Cisplatin resistance associated 10903

SLIT and NTRK-like family, member 2 84631

FLJ34870 protein 401013

KIAA0469 gene product 9903

Calcium channel, voltage-dependent, 10368 gamma subunit 3 Hypothetical protein LOC163782 163782

Solute carrier family 18 (vesicular 6570 monoamine), member 1 Caspase 7, apoptosis-related cysteine 840 protease Chemokine (C-C motif) receptor 1 1230

Protein C receptor, endothelial (EPCR) 10544

HRAS-like suppressor 2 54979

Serine dehydratase-like 113675

Apolipoprotein L, 4 80832

AXL receptor tyrosine kinase 558

X 006 protein 56985

FLN29 gene product 10906

2',3'-cyclic nucleotide 3' 1267 phosphodiesterase open reading frame 6 219285