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Thesis Is Presented for the Degree of Doctor of Philosophy of Curtin University of Technology
School of Biomedical Sciences Analysis of Candidate Genes within the 3p14-p22 Region of the Human Genome for Association with Bone Mineral Density Phenotypes Benjamin H Mullin This thesis is presented for the Degree of Doctor of Philosophy of Curtin University of Technology February 2011 To the best of my knowledge and belief this thesis contains no material previously published by any other person except where due acknowledgment has been made. This thesis contains no material which has been accepted for the award of any other degree or diploma in any university. Preface The experimental work contained within this thesis was performed in the Department of Endocrinology & Diabetes at Sir Charles Gairdner Hospital under the supervision of Doctor Cyril Mamotte, Associate Professor Scott Wilson, and Professor Richard Prince. All experimental work in this thesis was performed by myself unless otherwise stated. Benjamin H. Mullin, B.Sc. Publications arising from this thesis Mullin, B. H., Prince, R. L., Dick, I. M., Hart, D. J., Spector, T. D., Dudbridge, F. & Wilson, S. G. 2008. Identification of a role for the ARHGEF3 gene in postmenopausal osteoporosis. American Journal of Human Genetics , 82 , 1262-9. Mullin, B. H., Prince, R. L., Mamotte, C., Spector, T. D., Hart, D. J., Dudbridge, F. & Wilson, S. G. 2009. Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis. Bone , 45 , 387-91. Research grants received during completion of this thesis Wilson, S. G., Prince, R. L., Mamotte C., Mullin B. H. 2008. Influence of the ARHGEF3 gene on bone phenotypes. Arthritis Australia Project Grant ($14,500). -
Field Guide to Common Macrofungi in Eastern Forests and Their Ecosystem Functions
United States Department of Field Guide to Agriculture Common Macrofungi Forest Service in Eastern Forests Northern Research Station and Their Ecosystem General Technical Report NRS-79 Functions Michael E. Ostry Neil A. Anderson Joseph G. O’Brien Cover Photos Front: Morel, Morchella esculenta. Photo by Neil A. Anderson, University of Minnesota. Back: Bear’s Head Tooth, Hericium coralloides. Photo by Michael E. Ostry, U.S. Forest Service. The Authors MICHAEL E. OSTRY, research plant pathologist, U.S. Forest Service, Northern Research Station, St. Paul, MN NEIL A. ANDERSON, professor emeritus, University of Minnesota, Department of Plant Pathology, St. Paul, MN JOSEPH G. O’BRIEN, plant pathologist, U.S. Forest Service, Forest Health Protection, St. Paul, MN Manuscript received for publication 23 April 2010 Published by: For additional copies: U.S. FOREST SERVICE U.S. Forest Service 11 CAMPUS BLVD SUITE 200 Publications Distribution NEWTOWN SQUARE PA 19073 359 Main Road Delaware, OH 43015-8640 April 2011 Fax: (740)368-0152 Visit our homepage at: http://www.nrs.fs.fed.us/ CONTENTS Introduction: About this Guide 1 Mushroom Basics 2 Aspen-Birch Ecosystem Mycorrhizal On the ground associated with tree roots Fly Agaric Amanita muscaria 8 Destroying Angel Amanita virosa, A. verna, A. bisporigera 9 The Omnipresent Laccaria Laccaria bicolor 10 Aspen Bolete Leccinum aurantiacum, L. insigne 11 Birch Bolete Leccinum scabrum 12 Saprophytic Litter and Wood Decay On wood Oyster Mushroom Pleurotus populinus (P. ostreatus) 13 Artist’s Conk Ganoderma applanatum -
Peptide Chemistry up to Its Present State
Appendix In this Appendix biographical sketches are compiled of many scientists who have made notable contributions to the development of peptide chemistry up to its present state. We have tried to consider names mainly connected with important events during the earlier periods of peptide history, but could not include all authors mentioned in the text of this book. This is particularly true for the more recent decades when the number of peptide chemists and biologists increased to such an extent that their enumeration would have gone beyond the scope of this Appendix. 250 Appendix Plate 8. Emil Abderhalden (1877-1950), Photo Plate 9. S. Akabori Leopoldina, Halle J Plate 10. Ernst Bayer Plate 11. Karel Blaha (1926-1988) Appendix 251 Plate 12. Max Brenner Plate 13. Hans Brockmann (1903-1988) Plate 14. Victor Bruckner (1900- 1980) Plate 15. Pehr V. Edman (1916- 1977) 252 Appendix Plate 16. Lyman C. Craig (1906-1974) Plate 17. Vittorio Erspamer Plate 18. Joseph S. Fruton, Biochemist and Historian Appendix 253 Plate 19. Rolf Geiger (1923-1988) Plate 20. Wolfgang Konig Plate 21. Dorothy Hodgkins Plate. 22. Franz Hofmeister (1850-1922), (Fischer, biograph. Lexikon) 254 Appendix Plate 23. The picture shows the late Professor 1.E. Jorpes (r.j and Professor V. Mutt during their favorite pastime in the archipelago on the Baltic near Stockholm Plate 24. Ephraim Katchalski (Katzir) Plate 25. Abraham Patchornik Appendix 255 Plate 26. P.G. Katsoyannis Plate 27. George W. Kenner (1922-1978) Plate 28. Edger Lederer (1908- 1988) Plate 29. Hennann Leuchs (1879-1945) 256 Appendix Plate 30. Choh Hao Li (1913-1987) Plate 31. -
Forest Fungi in Ireland
FOREST FUNGI IN IRELAND PAUL DOWDING and LOUIS SMITH COFORD, National Council for Forest Research and Development Arena House Arena Road Sandyford Dublin 18 Ireland Tel: + 353 1 2130725 Fax: + 353 1 2130611 © COFORD 2008 First published in 2008 by COFORD, National Council for Forest Research and Development, Dublin, Ireland. All rights reserved. No part of this publication may be reproduced, or stored in a retrieval system or transmitted in any form or by any means, electronic, electrostatic, magnetic tape, mechanical, photocopying recording or otherwise, without prior permission in writing from COFORD. All photographs and illustrations are the copyright of the authors unless otherwise indicated. ISBN 1 902696 62 X Title: Forest fungi in Ireland. Authors: Paul Dowding and Louis Smith Citation: Dowding, P. and Smith, L. 2008. Forest fungi in Ireland. COFORD, Dublin. The views and opinions expressed in this publication belong to the authors alone and do not necessarily reflect those of COFORD. i CONTENTS Foreword..................................................................................................................v Réamhfhocal...........................................................................................................vi Preface ....................................................................................................................vii Réamhrá................................................................................................................viii Acknowledgements...............................................................................................ix -
Mantar Dergisi
11 6845 - Volume: 20 Issue:1 JOURNAL - E ISSN:2147 - April 20 e TURKEY - KONYA - FUNGUS Research Center JOURNAL OF OF JOURNAL Selçuk Selçuk University Mushroom Application and Selçuk Üniversitesi Mantarcılık Uygulama ve Araştırma Merkezi KONYA-TÜRKİYE MANTAR DERGİSİ E-DERGİ/ e-ISSN:2147-6845 Nisan 2020 Cilt:11 Sayı:1 e-ISSN 2147-6845 Nisan 2020 / Cilt:11/ Sayı:1 April 2020 / Volume:11 / Issue:1 SELÇUK ÜNİVERSİTESİ MANTARCILIK UYGULAMA VE ARAŞTIRMA MERKEZİ MÜDÜRLÜĞÜ ADINA SAHİBİ PROF.DR. GIYASETTİN KAŞIK YAZI İŞLERİ MÜDÜRÜ DR. ÖĞR. ÜYESİ SİNAN ALKAN Haberleşme/Correspondence S.Ü. Mantarcılık Uygulama ve Araştırma Merkezi Müdürlüğü Alaaddin Keykubat Yerleşkesi, Fen Fakültesi B Blok, Zemin Kat-42079/Selçuklu-KONYA Tel:(+90)0 332 2233998/ Fax: (+90)0 332 241 24 99 Web: http://mantarcilik.selcuk.edu.tr http://dergipark.gov.tr/mantar E-Posta:[email protected] Yayın Tarihi/Publication Date 27/04/2020 i e-ISSN 2147-6845 Nisan 2020 / Cilt:11/ Sayı:1 / / April 2020 Volume:11 Issue:1 EDİTÖRLER KURULU / EDITORIAL BOARD Prof.Dr. Abdullah KAYA (Karamanoğlu Mehmetbey Üniv.-Karaman) Prof.Dr. Abdulnasır YILDIZ (Dicle Üniv.-Diyarbakır) Prof.Dr. Abdurrahman Usame TAMER (Celal Bayar Üniv.-Manisa) Prof.Dr. Ahmet ASAN (Trakya Üniv.-Edirne) Prof.Dr. Ali ARSLAN (Yüzüncü Yıl Üniv.-Van) Prof.Dr. Aysun PEKŞEN (19 Mayıs Üniv.-Samsun) Prof.Dr. A.Dilek AZAZ (Balıkesir Üniv.-Balıkesir) Prof.Dr. Ayşen ÖZDEMİR TÜRK (Anadolu Üniv.- Eskişehir) Prof.Dr. Beyza ENER (Uludağ Üniv.Bursa) Prof.Dr. Cvetomir M. DENCHEV (Bulgarian Academy of Sciences, Bulgaristan) Prof.Dr. Celaleddin ÖZTÜRK (Selçuk Üniv.-Konya) Prof.Dr. Ertuğrul SESLİ (Trabzon Üniv.-Trabzon) Prof.Dr. -
Natur Und Heimat Floristische, Faunistische Und Ökologische Berichte
Natur und Heimat Floristische, faunistische und ökologische Berichte Herausgeber Westfälisches Museum für Naturkunde, Münster - Landschaftsverband Westfalen-Lippe - Schriftleitung: Dr. Brunhild Gries 54. Jahrgang 1994 Inhaltsverzeichnis Botanik Birken, S. : Die Mauerflora des Klosters Gravenhorst/Kreis Steinfurt. 115 G e r i n g h o ff, H. & F.J.A. D an i e 1 s. : Das Gentiano-Koelerietum grostietosum Korneck 1960 der Briloner Hochfläche. ..................................................................... 103 Ha p p e, J .: Verbreitung der Sommerlinde (Tilia platyphyllos, Scop.) in Nordrhein- Westfalen ........................................................................................ .......................... .. Lien e n b ecke r, H: Zur Ausbreitung des Kletternden Lerchensporns (Ceratocap- nos claviculata (L.) Liden) in Westfalen. .................... ............................................... 97 Raab e, U.: 100 Jahre "Flora von Westfalen" von Konrad Beckhaus.. ........ .......... ..... 11 Runge, F. : Neue Beiträge zur Flora Westfalens IV. .................. ............. ................... 33 R u n g e , F. : Der Vegetationswechsel nach einem tiefgreifenden Heidebrand II. .. 81 S o n n e b o r n , 1. & W. : Bortychium simplex Hitchcock - Einfache Mondraute: Der Fund einer verschollenen oder ausgestorbenen Pflanzenart auf dem Truppenübungs- platz "Sennelager". ...... .. ...................................................... ........................................ 25 Zoologie Bußmann, M. : Erstnachweis von Agapanthia cardui -
Toxic Fungi of Western North America
Toxic Fungi of Western North America by Thomas J. Duffy, MD Published by MykoWeb (www.mykoweb.com) March, 2008 (Web) August, 2008 (PDF) 2 Toxic Fungi of Western North America Copyright © 2008 by Thomas J. Duffy & Michael G. Wood Toxic Fungi of Western North America 3 Contents Introductory Material ........................................................................................... 7 Dedication ............................................................................................................... 7 Preface .................................................................................................................... 7 Acknowledgements ................................................................................................. 7 An Introduction to Mushrooms & Mushroom Poisoning .............................. 9 Introduction and collection of specimens .............................................................. 9 General overview of mushroom poisonings ......................................................... 10 Ecology and general anatomy of fungi ................................................................ 11 Description and habitat of Amanita phalloides and Amanita ocreata .............. 14 History of Amanita ocreata and Amanita phalloides in the West ..................... 18 The classical history of Amanita phalloides and related species ....................... 20 Mushroom poisoning case registry ...................................................................... 21 “Look-Alike” mushrooms ..................................................................................... -
New Developments in Amatoxin Poisoning
New Developments in Amatoxin Poisoning ACMT Annual Scientific Meeting San Juan, PR March 15, 2013 Disclosure S Todd Mitchell MD,MPH Principal Investigator: Prevention and Treatment of Amatoxin Induced Hepatic Failure With Intravenous Silibinin ( Legalon® SIL): An Open Multicenter Clinical Trial Consultant: Madaus-Rottapharm Amatoxin Poisoning: Overview • 95%+ of all fatal mushroom poisonings worldwide are due to amatoxin containing species. • 50-100 Deaths per year in Europe is typical. • Growing Problem in North America, especially Northern Califoriia USA 1976-2005: 126 Reported Cases 2006: 48 Reported Cases, 4 Deaths Summer 2008: 2 Deaths on East Coast September/October 2012: 2 deaths, 1 transplant among 15 total cases on the East Coast. Mexico 2005 & 2006: 19 Reported Deaths. Countless more in SE Asia, Indian Sub-Continent, South Africa Assam, India March 2008: 20 Deaths Swat, Pakistan 2006: Watsonville September 2006 • 57 yo former ER nurse, electrical contractor ingests 8 mushrooms from his property at 1800 on September 8. • Onset of sx ~0200. • Mushrooms identified as Amanita Phalloides by local expert amateur mycologist ~1500. • Presented to ER 24 hours post ingestion: BUN 37, Creat 2.0, Hgb 20.2, Hct 60.5, ALT 96. • Transfer to UCSF 9/10. INR 2.2, ALT 869 after Rx with hydration, antiemetics, repeated doses of charcoal, IV NAC, and IV PEN G. • 72 Hours: INR 4.5, ALT 2274, Bil 4.0. • Liver Transplant 9/14. 2007 Santa Cruz Cohort • EM age 82. ALT 12224, INR 5.4, Factor V 9% @ 72 hours. ALT 3570, INR 1.7, Factor V 49% @ 144 hours. Died from anuric renal failure 1/11. -
|H|||||||||| USOO5278143A United States Patent 19 11 Patent Number: 5,278,143 Shepro Et Al
|H|||||||||| USOO5278143A United States Patent 19 11 Patent Number: 5,278,143 Shepro et al. (45) Date of Patent: Jan. 11, 1994 (54) PROPHYLACTIC AND THERAPEUTIC OTHER PUBLICATIONS METHODS FOR TREATING NTER LEUKIN-MEDIATED EDEMAS Rudinger, Peptide Hormones, Parsons (Ed.) U. Park t Press, Baltimore, pp. 1-7 (1976). (75) Inventors: David Shepro, Boston, Mass.; J. Doukas et al., Blood, vol. 69, No. 6 pp. 1563-1569 (Jun. Steven Alexander, Nashville, Tenn. 1987). Frimmer, Chem. Abstracts, vol. 71, No. 99937m (1969). 73) Assignee: Trustees of Boston University, Wieland et al., Crit. Rev. Biochem. vol. 5, pp. 185-260 Boston, Mass. (1978). (21) Appl. No.: 807,668 Welbournet al., J. Appl. Physiol 70: 1364-1368 (1991). 22 illed: Dec. 16, 1991 Primary Examiner-Y. Christina Chan 22 Filed ec. 10, Attorney, Agent, or Firm-David Prashker Related U.S. Application Data 57 ABSTRACT m 63 continuation of ser. No. 416,905, Oct. 4, 1989, aban- Unique methods for treating interleukin-mediated ede doned, which is a continuation-in-part of Ser. No. mas in living subjects are provided comprising adminis 47,121, Oct. 4, 1989, abandoned, and a continuation- tering an effective amount of a composition selected in-part of Ser. No. 185,650, Apr. 25, 1988, abandoned. from the group consisting of phallotoxins, phallotoxin analogues, antamanide, or an antananide analogue to 51 Int. Cl. ........................ A61K 37/02; CK /6 the subject. The methods offer prophylactic and thera 52 576.5/35567; 17,353 peutic modes of treatment for both localized and sys s s 8 temic interleukin-mediated edemas. The compositions 58) Field of Search ................... -
Mushrooms on Stamps
Mushrooms On Stamps Paul J. Brach Scientific Name Edibility Page(s) Amanita gemmata Poisonous 3 Amanita inaurata Not Recommended 4-5 Amanita muscaria v. formosa Poisonous (hallucenogenic) 6 Amanita pantherina Deadly Poisonous 7 Amanita phalloides Deadly Poisonous 8 Amanita rubescens Not Recommended 9-11 Amanita virosa Deadly Poisonous 12-14 Aleuria aurantiaca Edible 15 Sarcocypha coccinea Edible 16 Phlogiotis helvelloides Edible 17 Leccinum aurantiacum Good Edible 18 Boletus parasiticus Not Recommended 19 For this presentation I chose the species for Cantharellus cibarius Choice Edible 20 their occurrence in our 5 county region Cantharellus cinnabarinus Choice Edible 21 Coprinus atramentarius Poisonous 22 surrounding Rochester, NY. My intent is to Coprinus comatus Choice Edible 23 show our stamp collecting audience that an Coprinus disseminatus Edible 24 Clavulinopsis fusiformis Edible 25 artist's rendition of a fungi species depicted Leotia viscosa Harmless 26 on a stamp could be used akin to a Langermannia gigantea Choice Edible 27 Lycoperdon perlatum Good Edible 28-29 guidebook for the study of mushrooms. Entoloma murraii Not Recommended 30 Most pages depict a photograph and related Morchella esculenta Choice Edible 31-32 Russula rosacea Not Recommended (bitter) 33 stamp of the species, along with an edibility Laetiporus sulphureus Choice Edible 34 icon. Enjoy… but just the edible ones! Polyporus squamosus Edible 35 Choice/Good Edible Harmless Not Recommended Poisonous Deadly Poisonous 2 3 4 5 6 7 8 Amanita rubescens (blusher) 9 10 -
Fso Newsletter 2021
FSO NEWSLETTER 2021 From the President, RICHARD FORTEY Every year that I report on the year’s fungus season for the FSO I make some claim about how peculiar the last twelve months have been compared with some years in the past. I think I am beginning to realize that there is no such thing as a “typical” mushroom year at all, and it is simply a fact that every year is different. 2020 was certainly different in one respect: Covid 19 put a brake on our communal foray activities, so that much of the peak season had to be solitary exploration of pastures and woodland—nothing against the rules in sampling on one’s own ... However, we were at least able to get something done for National Fungus Day in October, even though our regular foray around the Harcourt Arboretum was clearly impossible. Thanks to a concerted effort by our members we were able to assemble a wide variety of fruitbodies together to allow me to present a virtual fungus foray - filmed inside an open barn - which was subsequently made available online through the Oxford University Botanic Garden website. Thanks are due to the Arboretum for making this happen. Judging by the fact that is has been viewed more than 1000 times by the time of writing this report, it was something of a success. Highlights of the presentation were a prodigious specimen of Amanita strobiliformis (Warted Amanita) found by Judy Webb and a colossal Ganoderma resinaceum from Molly Dewey’s garden. Some say that the star of the show was actually a ground beetle that kept on reappearing throughout the shooting of the video, moving from fungus to fungus alongside the presenter! Assorted Russula species + a few Lactarius (Molly Dewey) Amanita strobiliformis (Judy Webb) 2020 was unusual not only for the ‘lockdown’ and its aftermath but also for the long, sunny, and very dry summer. -
Phalloidin, Amanita Phalloides
Phalloidin, Amanita phalloides sc-202763 Material Safety Data Sheet Hazard Alert Code EXTREME HIGH MODERATE LOW Key: Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME Phalloidin, Amanita phalloides STATEMENT OF HAZARDOUS NATURE CONSIDERED A HAZARDOUS SUBSTANCE ACCORDING TO OSHA 29 CFR 1910.1200. NFPA FLAMMABILITY1 HEALTH4 HAZARD INSTABILITY0 SUPPLIER Company: Santa Cruz Biotechnology, Inc. Address: 2145 Delaware Ave Santa Cruz, CA 95060 Telephone: 800.457.3801 or 831.457.3800 Emergency Tel: CHEMWATCH: From within the US and Canada: 877-715-9305 Emergency Tel: From outside the US and Canada: +800 2436 2255 (1-800-CHEMCALL) or call +613 9573 3112 PRODUCT USE Toxic bicyclic heptapeptide (a member of the family of phallotoxins) isolated from the green mushroom, Amanitra phalloides Agaricaceae (the green death cap or deadly agaric). Binds to polymeric actin, stabilising it and interfering with the function of endoplasmic reticulum and other actin-rich structures. NOTE: Advice physician prior to working with phallotoxins. Prepare Emergency procedures. SYNONYMS C35-H48-N8-O11-S, phalloidine, "Amanita phalloides Group I toxin", "Amanita phalloides Group I toxin", "mushroom (green death cap/ deadly agaric) phallotoxin/ peptide", "cyclopeptide/ bicyclic bioactive heptapeptide" Section 2 - HAZARDS IDENTIFICATION CANADIAN WHMIS SYMBOLS EMERGENCY OVERVIEW RISK Very toxic by inhalation, in contact with skin and if swallowed. POTENTIAL HEALTH EFFECTS ACUTE HEALTH EFFECTS SWALLOWED ■ Severely toxic effects may result from the accidental ingestion of the material; animal experiments indicate that ingestion of less than 5 gram may be fatal or may produce serious damage to the health of the individual. ■ At sufficiently high doses the material may be hepatotoxic(i.e.