GANAB Antibody Cat. No.: 15-233

GANAB Antibody

Immunohistochemistry of paraffin-embedded Immunohistochemistry of paraffin-embedded mouse brain using rat brain using GANAB antibody (15-233) at GANAB antibody (15-233) at dilution of 1:150 (40x lens). dilution of 1:150 (40x lens).

Immunofluorescence analysis of C6 cells using Immunofluorescence analysis of NIH-3T3 cells using GANAB GANAB antibody (15-233) at dilution of 1:100. antibody (15-233) at dilution of 1:100. Blue: DAPI for nuclear Blue: DAPI for nuclear staining. staining.

September 29, 2021 1 https://www.prosci-inc.com/ganab-antibody-15-233.html Immunofluorescence analysis of U-2 OS cells Immunofluorescence analysis of C6 cells using GANAB antibody using GANAB antibody (15-233) at dilution of (15-233) at dilution of 1:100. Blue: DAPI for nuclear staining. 1:100. Blue: DAPI for nuclear staining.

Immunofluorescence analysis of NIH-3T3 cells using GANAB antibody (15-233) at dilution of 1:100. Blue: DAPI for nuclear staining.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of IMMUNOGEN: human GANAB (NP_001265123.1).

TESTED APPLICATIONS: IF, IHC, WB

WB: ,1:500 - 1:2000

APPLICATIONS: IHC: ,1:50 - 1:200

IF: ,1:50 - 1:200

POSITIVE CONTROL: 1) U-87MG

2) Raji

3) HepG2

4) HeLa

5) Mouse brain

6) Mouse liver

PREDICTED MOLECULAR Observed: 112kDa WEIGHT:

September 29, 2021 2 https://www.prosci-inc.com/ganab-antibody-15-233.html Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: GANAB

GANAB, G2AN, Glucosidase, alpha, Glucosidase, alpha neutral AB, Neutral alpha- ALTERNATE NAMES: glucosidase AB, Alpha-glucosidase 2, Glucosidase II subunit alpha, GLUII, KIAA0088, Neutral AB

GENE ID: 23193

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature BACKGROUND: glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 29, 2021 3 https://www.prosci-inc.com/ganab-antibody-15-233.html