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a - FILE TEMPLE UNIVERSITY vmcp\d HEALTH SCIENCES CENTER DEPARTMENT OF AND PHYSIOLOGY 3223 NORTH BROAD STREET PHILADELPHIA, PENNSYLVANIA 19140

DIVISION OF BIOPHYSICS

Dr. E. Feigenbaum Dept. Computer Science Stanford University Stanford, California

Dear Doctor Feigenbaum:

On behalf of the International Scientific Committee thanks for accepting to participate at the Nobel and Galileian celebration to take place May 5-10 in San Remo and Rome.

The final scientific programs for both San Remo and Rome, with the specific indication (topic and time) of your contribution, are included. They have already gone to press, and as such, you should receive a copy in due time of the entire . program!

As per previous correspondence, the closing ceremony for the Nobel celebration will take place on Saturday, May 7th in San Remo at the presence of the King of Sweden and the President of . the Italian Republic . While the opening ceremony for Galileo Galilei celebration will take place Monday morning, May 9th in Rome, at the Vatican, with the presence of Pope John Paul II and the President Pertini of the Italian Republic.

time, but if^you should need any further assistance, please contact Mrs. Deramo in Rome at 06-6799973 (direct line to the INFN-Pres-

Looking forward to being with you at San Remo and Rome for these historic events, I remain. Sincerely yours ,

>A^ , _*» Claudio Nicolini Professor and Director PS Until March 31 you may contact me at 215-221-4969, after that i will be in Europe until May (39-10-572925). \ VILLA NOBEL May 5-6 1983 (SAN REMO) SYMPOSIUM FOR THE 150th ANNIVERSARY OF ALFRED NOBEL BIRTH

NEW FRONTIERS AT THE CROSSING OF LIFE AND PHYSICAL SCIENCES Chairman: C. Nicolini

5 May Morning Session Chairman : C . Nico lini 9 : 00 Opening Lecture : '0'

9:50 * Cancer at the DNA Level" 10 : 40 Howard Temin" Retrovirusses and evolution 11:30 BREAK -v 12:00 " - "Oncogenes: the beginning of the molecular description of a cancer"

Afternoon Session Chairman: J. Watson 15:00 Alexander Rich -"DNA Structure : Left -handedness and gene expression 15:50 Aaron Klug* - "Structure of chromatin" 16:40 BREAK 17:2-0 Edwin Bradbury - "Histones structure and modification 18:00 Claudio Nicolini - "Nuclear structure: from envelope to genes"

OVER -NOBEL LAUREATE ,-»

MAY 9-10, 1983 ROMA PALAZZO BARBERINI

SYMPOSIUM On"gaLILETAN SCIENCES"TODAY FOR THE 350TH ANNIVERSARY OF GALILEO GALILEI

TUESDAY AFTERNOON SESSION ON "NEW FRONTIERS AT THE CROSSING OF LIFE AND PHYSICAL SCIENCES" CHAIRMAN: CLAUDIO NICOLINI

PART I - Chairman David Hubel* 14:30 Leon Cooper - "Brain and Mind: Metaphore and Reality in a Galileian Science Today" 15:00 Malvin Calvin" - "Renewable fuels and materials" 15:30 Francois Jacob" - "Mouse embryo and molecules 16:00 Donald Glaser - "A physicist view of vision" 16:20 BREAK

PART II - Chairman James Watson" 16:30 Howard Temin* - "Incorporation of information into DNA" 16:50 Alexander Rich - "Right- and left-handed DNA" 17:1 C Aaron Klug" - "Structure of chromatin" 17:30 Edwin Bradbury - "Neutron and NMR of DNA-histones interaction" 17:50 BPvEAK

PART 111- Chairman Allan Cormack* 18:00 Claudio Nicolini - "CeLl Biophysics and cancer" 18:20 - "NMR imaging" 18:40 Harlyn Halvorson - "Genetic engineering: an industrial revolution Edward Feigenbaum 19:00 - "Artificial intelligence" n 19:30 Closing Remarks

"NOBEL LAUREATE Attending Galileian celebration will also be Ilya Prigogine*& and Paul Ts'o a -