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Practical Immunodermatology Xing-Hua Gao • Hong-Duo Chen Editors Practical Immunodermatology Xing-Hua Gao • Hong-Duo Chen Editors Practical Immunodermatology Editors Xing-Hua Gao Hong-Duo Chen Dermatology Dermatology The first affiliated Hospital China Medical The first affiliated Hospital China Medical University University Shenyang Shenyang China China ISBN 978-94-024-0900-0 ISBN 978-94-024-0902-4 (eBook) DOI 10.1007/978-94-024-0902-4 Library of Congress Control Number: 2016960305 © Springer Science+Business Media Dordrecht 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer Science+Business Media B.V. Dordrecht The registered company address is Van Godewijckstraat 30, 3311 GX Dordrecht, The Netherlands Contents Part I The Fundamentals of Human Immune System 1 Components of the Immune System ����������������������������������������������������������������������� 3 Haoyu Sun, Rui Sun, and Zhigang Tian 2 The Innate Immunity ����������������������������������������������������������������������������������������������� 23 Haoyu Sun, Cheng Sun, and Zhigang Tian 3 The Adaptive Immunity ������������������������������������������������������������������������������������������� 27 Haoyu Sun, Cheng Sun, and Zhigang Tian 4 Immunotolerance and Immunoregulation ������������������������������������������������������������� 39 Haoyu Sun, Cheng Sun, and Zhigang Tian 5 Immnopathology ������������������������������������������������������������������������������������������������������� 49 Cheng Sun, Haoyu Sun, and Zhigang Tian Part II Skin Immune System 6 Cells in the Skin ��������������������������������������������������������������������������������������������������������� 63 Xiaoqin Wang, Xing-Hua Gao, Xilin Zhang, Li Zhou, Qing-Sheng Mi, Yuxiao Hong, Bing Song, Naomi McGovern*, Shawn Lim*, Mark B. Y. Tang, Florent Ginhoux, Jinyan Wang, Changlong Lu, Song Zheng, Jianjun Qiao, Hong Fang, George Man, and Mao-Qiang Man 7 Humoral Factors in the Skin ����������������������������������������������������������������������������������� 115 Umberto Cornelli, Changlong Lu, Xun Sun, Jinyan Wang, Roberto Perricone, Eleonora Ballanti, and Yun-Feng Gao Part III Immunodermatological Conditions 8 Skin Diseases Caused by Factors from the Environment ������������������������������������� 145 Lei Ma, Min Chen, Zhenzong Fa, Weihua Pan, Wanqing Liao, Xing-Hua Gao, Wei Huo, Yang Yang, Hong-Duo Chen, H. M. Holahan, A. C. Laureano, R. A. Schwartz, Xiao-ying Chen, Alex Anstey, Joachim Bugert, Tsu-Man Chiu, Yi-Giien Tsai, Shivani Nanda, Henry W. Lim, Wen-Hui Wang, Lin-­Feng Li, Yong-Hu Sun, and Fu-Ren Zhang 9 Diseases with Underlining Internal Conditions ����������������������������������������������������� 199 Melissa Danesh, Jenny E. Murase, Zhirong Yao, Ruhong Cheng, Huaguo Li, Liangchun Wang, Jian-­Zhong Zhang, and Jin Wei v vi Contents 10 Multifactorial Diseases with Immunological Involvement ����������������������������������� 221 Ting Xiao, Hong-Duo Chen, Jixin Gao, Gang Wang, Jeffrey D. Cizenski, Darlene Gou, Alan Menter, Li-Ping Zhao, Ru Yan, Yan Wu, Jinping Yuan, Hong-­Hui Xu, Xing-Hua Gao, and Hong-Duo Chen 11 Diseases Caused by Genetic or Congenital Defects in the Immune System or Skin Immune System ����������������������������������������������������������������������������� 259 Albert Gutierrez, Mark R. Pittelkow, Liyan Xi, Xiaowen Huang, and Sweta Rai 12 Neoplasms ����������������������������������������������������������������������������������������������������������������� 279 Ke-Hua Li, Thomas Griffin, Neda Nikbakht, Le Qu, Hong-­Duo Chen, Chundi He, and Li-Xin Xia 13 Autoimmune Dermatoses ����������������������������������������������������������������������������������������� 297 Jie Zheng, Meng Pan, S. Gianfaldoni, A. M. D’Erme, T. Lotti, Xingqi Zhang, Peng Zhang, Jin Yuan, Qianjin Lu, Ken Hashimoto, and Fiona Lewis Part IV Immuno-Techniques, Immuno-Diagnosis and Immunotherapy in Dermatology 14 Tissue or Cell-Based Techniques ����������������������������������������������������������������������������� 343 Tammie Ferringer, Dirk Elston, Jang-June Park, Leihong Xiang, Yuling Shi, Matthew Weiland, Ruiqun Qi, and Zhenghong Di 15 Immunotherapy ��������������������������������������������������������������������������������������������������������� 367 Sebastian Volc, Kamran Ghoreschi, and Hui Shen Erratum ����������������������������������������������������������������������������������������������������������������������������� E1 Index ����������������������������������������������������������������������������������������������������������������������������������� 383.
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