Anti-CAMK2B Monoclonal Antibody (DCABH- 10166) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-CAMK2B monoclonal antibody (DCABH- 10166) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal to CaMKII beta

Antigen Description CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses, it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.

Immunogen Recombinant fragment: FEPEALGNLV EGMDFHRFYF ENLLAKNSKP IHTTILNPHV HVIGEDAACI AYIRLTQYID GQGRPRTSQS EETRVWHRRD GKWQNVHFHC SGAPVAPL, corresponding to amino acids 405-502 of human CaMKII beta (NP_742078) with a proprietary tag.

Isotype IgG1

Source/Host Mouse

Species Reactivity Rat, Human

Purity Protein A purified

Conjugate Unconjugated

Applications WB, ELISA, ICC/IF, Flow Cyt

Positive Control WB: The immunogen; HeLa and PC12 cell lysates ICC/If: HeLa cell

Format Liquid

Size 100 μg

Buffer Preservative: None; Constituents: 1X PBS, pH 7.2

Preservative None

Storage store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Ship Shipped at 4°C.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Gene Name CAMK2B calcium/calmodulin-dependent protein kinase II beta [ Homo sapiens ]

Official Symbol CAMK2B

Synonyms CAMK2B; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin dependent protein kinase (CaM kinase) II beta , CAMKB; calcium/calmodulin-dependent protein kinase type II subunit beta; calcium/calmodulin dependent protein kinase type II be

Entrez Gene ID 816

Protein Refseq NP_001211

UniProt ID A4D2J9

Chromosome Location 7p14.3-p14.1

Pathway Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; CREB phosphorylation through the activation of CaMKII, organism- specific biosystem; CREB phosphorylation through the activation of Ras, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem;

Function ATP binding; actin binding; calmodulin binding; calmodulin-dependent protein kinase activity; nucleotide binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]