Authors: Peter D. Karp Suzanne Paley Julio Collado-Vides Victor H Tierrafria Ingrid Keseler Markus Krummenacker Cesar Bonavides-Martinez An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Carol Fulcher Ian Paulsen Socorro Gama-Castro Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. EcoCyc: Escherichia coli K-12 substr. MG1655 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari Amanda Mackie Alberto Santos-Zavaleta a heme(III) -bound CcmCDE α-D- complex Fuc4NAc- succinate an apo-[c-type (1->4)-β-D- asp D-selenomethionine a heme(III) cytochrome] ile glutathione ManNAcA- ethidium asp succinate D-fructofuranose L-ornithine N-acetyl-DL-methionine -bound with reduced L-alanyl-γ-D- cys 2,3- uridine 2-deoxy-D-glucose + D-cycloserine lys antimonous acid guanosine L-methionine S-oxide val guanine guanine (1->4)- succinate uridine putrescine sulfadiazine L-tartrate D-tartrate succinate (S)-2-hydroxybutanoate (S)-2-hydroxybutanoate salicin Li agmatine poly-β-1,6- leu CcmCDE L-cysteine cob(I)inamide O-acetyl-L-serine O-acetyl-L-serine β maltose putrescine (2R,4S)-2-methyl-2,3,3,4- α α β glutamyl-meso- β α α leu GlcNAc- 1-( -D 2-dehydro- didehydro- cytidine cytidine a drug (2R,4S)-2-methyl-2,3,3,4- asp fumarate fumarate (S)-lactate (S)-lactate methyl- -D-galactopyranoside 5-dehydro-D-gluconate N-acetyl-D-mannosamine methyl -D-glucoside arbutin D-glucarate D-glucarate D-serine phosphinate arg arg antimonous acid urea xanthine -D-cellobiose 2-O-(α-D- -D-cellobiose , - N-acetyl-D- L-ascorbate N-(4- L-galactose 4-hydroxybenzoate glutathione inosine [+ 2 more] hypoxanthine hypoxanthine citrate maltotriose molybdate pro L-ornithine ser succinate fumarate melibiose ala formate arg adenine adenine diaminopimelate S-methyl-L- xanthosine a C4-dicarboxylate met complex residues cob(I)alamin (R)- tyr cys cys pyridoxine PP-Und pyridoxamine ribofuranosyl) 3-deoxy-D- L-gulonate inosine guanosine tetrahydroxytetrahydrofuran tetrahydroxytetrahydrofuran succinate (S)-malate succinate succinate glycolate glycolate D-glucopyranose methyl-β-D-galactoside melibionate D-fructuronate D-galactopyranose L-idonate [+ 4 more] D-glucopyranose methyl β-D-glucoside N-acetyl-D-glucosamine methyl-β-D-galactoside galactarate galactarate D-ala formate L-canavanine arsenous acid DL-glyceraldehyde thymine urate salicin mannosyl)- N,N'-diacetylchitobiose trehalose aminobenzoyl) L-fucose met L-galactonate 2-oxoglutarate maltotetraose glycine betaine [+ 2 more] choline thr fumarate (S)-malate fumarate pyruvate pyruvate D-gluconate D-gluconate xanthine xanthine H O propanoate D-galactonate glucosamine methionine pseudouridine orotate cytosine pantothenate nicotinamide [+ 7 more] [+ 8 more] fumarate acetate (R)-lactate (R)-lactate maltose D-galactopyranose melibiose D-gluconate D-glucopyranose D-glucopyranose D-glucosamine melibiose D-glycerate [+ 3 more] arg [+ 3 more] uracil xanthine arbutin D-glycerate 2 D-arabinose gluconate fumarate D-gluconate D-glycerate lysine / uracil -L-glutamate L-methionine/ glutathione murein mannose- glucose- arginine / L-arginine N,N'- trehalose- L-ascorbate glutathione D-methionine CcmCDE Sec Holo- vitamin / L-cysteine pyridoxine transport of 2,3-diketo-L- maltose ABC molybdate putrescine Autoinducer- tripeptide YfjW YdgC YebE AaeAB KbaZ ABC YahG DctA NepI YbjT YjeH LeuE GhxP GhxQ CodB YmiC B ABC MdtD PanF TyrP BluF ABC EamB EamA SapA WzxE PnuC YchQ LgoT KdgT gulonate:Na + KgtP CitT ABC ProP NupC NupG PotE ABC EmrE 2 ABC TqsA BetT TdcC TtdT DcuB DauA DcuB DcuA DcuC DcuC DcuA SatP Smp CstA BtsT GlcA LldP YmgF MalX MglBAC MelB GntU GntT GntP GalP IdnT specific PTS specific PTS BglF NagE MelB MelB GarP GudP AlaE CycA Hda FocA FocB ornithine ArgO AdiC ABC ArsB GlpF RutG UraA UacT AscF XanQ XanP AdeP AdeQ MngA AqpZ diacetylchitobiose- specific PTS PutP DgoT YdiN PgaCD specific PTS MmuP PqiA AbgT FucP PsuT XapB YoaJ YdeE YhbE SanA YgiZ YcjF YtcA RodZ YbjO ABC complex Translocon 12 transporter pyridoxamine transporter ABC enzyme II enzyme II ABC transporter specific PTS enzyme II enzyme II enzyme II transporter transporter transporter exporter symporter transporter exporter transporter transporter YcaL CydDC transporter YobB ile α ethidium phosphinate poly-β-1,6- leu an apo-[c-type O-acetyl-L-serine O-acetyl-L-serine -D- (2R,4S)-2-methyl-2,3,3,4- antimonous acid 4-hydroxybenzoate a C4-dicarboxylate guanosine guanine guanine cytosine (R)- 1-(β-D 2-dehydro- uridine uridine asp asp fumarate succinate succinate (S)-2-hydroxybutanoate (S)-2-hydroxybutanoate D-glucopyranose methyl-β-D-galactoside methyl-α-D-galactopyranoside D-fructuronate D-galactopyranose 5-dehydro-D-gluconate salicin 6-phosphate N-acetyl-D-glucosamine 6-phosphate methyl-β-D-galactoside D-glucarate D-glucarate ala D-cycloserine formate L-canavanine antimonous acid xanthine uracil urate β-D-cellobiose 6'-phosphate 2-O-(6- N-acetyl-D- N-(4- L-galactose val Fuc4NAc- L-galactonate 2-oxoglutarate citrate maltose pro sulfadiazine tetrahydroxytetrahydrofuran choline ser succinate fumarate fumarate fumarate pyruvate pyruvate D-gluconate D-gluconate melibiose formate arsenous acid xanthine xanthine H O propanoate D-galactonate S-methyl-L- pseudouridine met cytochrome] tyr cys cys ribofuranosyl) 3-deoxy-D- cytidine cytidine L-ornithine putrescine succinate maltose D-galactopyranose melibionate D-gluconate D-glucopyranose L-idonate arbutin 6-phosphate melibiose galactarate galactarate arg thymine salicin 6-phosphate 2 α α aminobenzoyl) L-fucose orotate inosine leu hypoxanthine hypoxanthine protoheme cob(I)inamide pantothenate pyridoxine (1->4)-β-D- pyridoxamine 2,3- a drug (2R,4S)-2-methyl-2,3,3,4- D-tartrate (S)-malate fumarate acetate (S)-lactate (S)-lactate D-fructofuranose 6-phosphate methyl α-D-glucoside 6-phosphate D-glucosamine 6-phosphate D-serine arg urea xanthine adenine adenine γ phospho- β-D-cellobiose 6'-phosphate , - glucosamine L-ascorbate xanthosine glutathione D-selenomethionine with reduced glutathione maltotriose molybdate glycine betaine thr β + L-alanyl- -D- methionine cob(I)alamin nicotinamide gluconate didehydro- succinate inosine guanosine putrescine L-tartrate fumarate fumarate succinate glycolate glycolate melibiose D-gluconate 2-deoxy-D-glucose 6-phosphate D-glucopyranose 6-phosphate methyl -D-glucoside 6-phosphate Li D-glycerate D-glycerate D-ala L-ornithine agmatine arg DL-glyceraldehyde uracil arbutin 6-phosphate α-D- N,N'-diacetylchitobiose 6'-phosphate trehalose 6- 6-phosphate -L-glutamate D-arabinose N-acetyl-DL-methionine met A cys ManNAcA- maltotetraose [+ 2 more] tetrahydroxytetrahydrofuran glutamyl-meso- GndA L-cysteine L-gulonate [+ 7 more] [+ 8 more] (S)-malate asp (R)-lactate (R)-lactate N-acetyl-D-mannosamine 6-phosphate D-glucopyranose 6-phosphate [+ 3 more] lys [+ 3 more] mannosyl)- phosphate L-methionine S-oxide (1->4)- diaminopimelate YodB residues succinate [+ 4 more] arg D-glycerate [+ 2 more] GlcNAc- succinate PP-Und lipid II (meso a mature peptidoglycan D- a [protein] with a protein L-threonine 3- cellulose diaminopimelate containing) peptidoglycan alanyl-DAP crosslink an N-terminal with incorrect YqiD O-phosphate peptidoglycan (meso- L-arginine disulfide bondsprotein Cofactor, Carrier, and Vitamin Biosynthesis Polymeric Compound C1 Compound Utilization GfcB L-threonine O- glycosyltransferase: diaminopimelate and Assimilation disulfide glycogen degradation I Carbohydrate Degradation Degradation containing) peptidoglycan DD- 3-phosphate L-lyxose L-rhamnose degradation I D-arabinose degradation I fucose degradation D-allose an inactive a [DNA]-3'- 1-chloro-2,4- 3-oxo-(5Z)- a holo-[EntF a [protein]- (S)-1-pyrroline- D-mannitol mrcA alkaline isomerase: biotin biosynthesis I a reduced D-cellobiose 6'-phosphate [DNA] a 2'-deoxyribonucleoside sn-glycerol sn-glycerol an N-modified glutathione a [protein]-L-histidine a [protein]-L-lysine an unfolded tellurite endopeptidase: phosphatase: superpathway of ubiquinol-8 superpathway of menaquinol-8 biosynthesis I S-adenosyl-L-methionine salvage I superpathway of heme b biosynthesis from uroporphyrinogen-III NAD salvage pathway I (PNC VI cycle) Fermentation mixed acid fermentation degradation muropeptide degradation formaldehyde oxidation ribonucleoside SAM [DNA] a myristoyl-[acp] a palmitoyl-[acp] cys L-seryl-carrier ser L-tyrosine 5-carboxylate 1-phosphate peptidoglycan phosphatase dsbG a cellodextrin YdcF cytochrome c biogenesis (system I type) superpathway of thiamine diphosphate biosynthesis I superpathway of adenosylcobalamin salvage from cobinamide I Secondary Metabolite Biosynthesis Tetrapyrrole Biosynthesis degradation flavodoxin 5'-triphosphate hydroxyl 3-phosphate 3-phosphate aminoacyl-[tRNA] dinitrobenzene dodecenoyl-CoA GTP protein acetate acetate mepS aphA biosynthesis (early decarboxylation) a glycogen β II (glutathione-dependent) triphosphate protein-histidine peptidyl-lysine N- protein] phosphate fused DNA- mannitol-1- ATPase: tellurite glycosyltransferase: peptidoglycan lytic aminopeptidase: iap protein α-L-rhamnopyranose D-arabinopyranose -L-fucopyranose L-cysteine phosphotyrosine- glycolate ActP glycolate peptidoglycan L-threonine O- an apo-[c-type β-L-lyxopyranose D-allopyranose L-alanyl-γ-D-glutamyl-meso- reductase auto-kinase: zraS acetyltransferase: binding phosphatase: diguanylate reductase: a malonyl-[acp] + tetrapyrrole biosynthesis glycogen desulfidase: cyuA protein ravA mrcB endotransglycosylase: slt disulfide chorismate SAH cob(II)inamide uroporphyrinogen-III NAD methylerythritol phosphate pathway I phosphoenolpyruvate D-allose 6-phospho-β-D-glucosyl- 3' -> 5' 3' -> 5' glutathione S- patZ acetyl-CoA C- lpd tellurite tellurite DD- 3-phosphate malonyl-CoA IPP cytochrome] cys autoinducer AI-2 biosynthesis I siroheme biosynthesis L-lyxose L-rhamnose D-arabinose L-fucose 2,6-diaminopimeloyl-D-alanine formaldehyde DNA peptidyl- protein-histidine L-serine- transcriptional hxpB cyclase: dgcN chaperonin peptidoglycan peptidoglycan lytic isomerase: I (from glutamate) phosphorylase: kinase: (1,4)-D-glucose exodeoxyribonuclease: exonuclease: acyl-acp:sn- acyl-acp:sn- transferase: acyltransferase: L-cysteine phosphatase: etp endopeptidase phosphatase: methyltransferase: with reduced L- isomerase: mutarotase: isomerase: fucI mutarotase: fucU L,D- ribonucleoside polymerase: polA autokinase: pyrS peptidyl-lysine N- -[holo repressor sugar diguanylate ATPase: tellurite arg a peptide dsbC StfR YnbA isochorismate cobinamide uroporphyrinogen + glgP glucohydrolase: chbF yqgF xthA glycerol-3- glycerol-3- tRNA yfcF fadI desulfhydrase: tnaA protein-tyrosine glycosyltransferase: endotransglycosylase: MepH: mepH phoA a protein isopentenyl- S-adenosylhomocysteine cysteine residues L-cysteine:[protein NAD synthetase, D-glyceraldehyde pyruvate phosphoenolpyruvate pyruvate rhaA rhaM alsK acetyltransferase: / proline bioC synthase: menF adenosyltransferase: decarboxylase: hemE uroporphyrinogen-III aldehydo-D-allose carboxypeptidase: triphosphate DNA polymerase: phosphate 1-O- phosphate 1-O- hydrolase: protein-histidine EntF] phosphatase: cyclase: dgcC groL groS reductase: MdtH pbpC emtA with correct a malonyl-[acp] apo-c-type glutamine + 3-phosphate glu D-ribulose α-L-fucopyranose β exodeoxyribonuclease L-cysteine phosphatase: peptidoglycan DD- thr diphosphate ∆- nucleosidase: mtn cysteine] NAD SAM carboxylase: ppc kinase: pykF an α-limit dextrin L-xylulose ldcA S-(hydroxymethyl) reductase 6-phospho- -D-glucosyl- exodeoxyribonuclease umuC umuD glutathione S autokinase: phoR rimI 3-ketoacyl- ligase: dehydrogenase ybiV diguanylate narY btuR dependent: nadE S-adenosyl-L- β-L-rhamnopyranose 6-phosphate acyltransferase acyltransferase arfB desulfhydrase: cysM wzb chaperone a nascent peptidoglycan peptidoglycan lytic disulfide bonds methyl ester isomerase: idi cytochrome sulfurtransferase: synthetase, NH - glutamate--tRNA glutathione (1-4)-D-glucose 3' -> 5": yhbQ I: sbcB -transferase: CoA / 1-pyrroline- narZ narV endopeptidase: isochorismate coproporphyrinogen III 3 pyruvate γ activase: nrdG DNA (glycerol-3- protein histidine peptidyl-lysine N- entF cyclase: dgcM ATPase: with (L-alanyl-γ-D-glutamyl- S-ribosyl-L- export: yajC [corrinoid 1-deoxy-D- methionine:uroporphyrinogen- L-xylulose D-ribulokinase: L-fucose allose-6- L-alanyl- -D-glutamyl- glucohydrolase: bglB (glycerol-3- peptidyl- gstA thiolase: L-cysteine protein-tyrosine mannitol-1- endotransglycosylase: ampH iscS dependent: nadE ligase: gltX kinase: pykA limit dextrin α-1,6- L-rhamnose S-(hydroxymethyl) 3' -> 5' ssDNA polymerase: polB 3' -> 5' ssDNA autokinase: arcB acetyltransferase: 5-carboxylate YedE homocysteine secF secD adenosyltranferase]- xylulose-5- III C-methyltransferase: cysG oxaloacetate kinase: fucK isomerase: fucI phosphate meso-diaminopimelate phosphate phosphate tRNA phosphatase: diguanylate dnaK tellurite meso-2,6-diaminopimeloyl-D- mltD RhsB DMAPP Glu β exonuclease: exonuclease: fadA desulfhydrase: cysK phosphatase: peptidoglycan DD- 2-succinyl-5- L-cysteine nicotinate adenine dinucleotide NMN an L-glutamyl-[tRNA ] precorrin-1 glucohydrolase: isomerase: glutathione an active 6-phospho- -D-glucosyl- DNA acyltransferase) acyltransferase) protein histidine yiaC dehydrogenase hxpA cyclase: dgcZ reductase: alanyl-D-alanine) pentapeptide secY secG cob(II)inamide coproporphyrinogen III coproporphyrinogen phosphate SAH lyxK isomerase: murein tripeptide hydrolase: a seryl-[EntF pphB chaperone peptidoglycan lytic enolpyruvyl- desulfurase: glgX rhaA D-ribulose 1-phosphate L-fuculose dehydrogenase: 5'-deoxyadenosine a flavodoxin (1,4)-D-glucose tatD tatD 2,4-dinitrophenyl- L-cysteine PutA: putA AsmA endopeptidase: geranyl secE yidC synthase: dxs pyruvate L-xylulose rpiB met ribonucleoside polymerase: dnaE : plsB : plsB pth autokinase: atoS peptidyl-lysine N- L-seryl-carrier sugar diguanylate ATPase: narG endotransglycosylase: a 3-oxoglutaryl- 6-hydroxy-3- S-ribosylhomocysteine sufS dehydrogenase: hemN III oxidase: hemF S-adenosyl-L- malate amidase: mpaA frmA semiquinone glucohydrolase: ascB exodeoxyribonuclease exodeoxyribonuclease S-glutathione desulfhydrase: malY protein-tyrosine mepA diphosphate an apo-[c-type nicotinate-nucleotide S-adenosylhomocysteine glutamyl-tRNA 5-phosphate triphosphate DNA [+ 21 isozymes] acetyltransferase: (3Z)-dec-3- protein] glu phosphatase: cyclase: dgcT htpG narH narI peptidoglycan DD- peptidoglycan DD- mltB [acp] methyl ester cyclohexene- lyase: luxS an [L-cysteine NMN methionine:precorrin-1 C- dehydrogenase: keto-L-rhamnulose L-fuculokinase: D-allulose 6- I: sbcB 3' -> 5": yhbQ a [protein]-N- acetyl-CoA L-cysteine phosphatase: cytochrome] a [ThiS sulfur- adenylyltransferase: reductase: hemA a debranched reductase polymerase: dinB yjaB enoyl-CoA carboxypeptidase: transpeptidase: mrcA murein DD- QmcA synthase: ispA [corrinoid nucleosidase 1-deoxy-D-xylulose nucleosidase: mtn α maltotetraose L-xylulose 5- D-ribulose- fucK phosphate L-alanyl-D-glutamate S-formylglutathione 1-myristoyl- 1-palmitoyl- yidA [+ 3 isozymes] a protein tellurite peptidoglycan lytic YcgV 1-carboxylate desulfurase]-S- protoporphyrinogen IX protoporphyrinogen IX methyltransferase: cysG mdh D-lactate -limit dextrin 3' -> 5' an uncharged phospho-L-histidine desulfhydrase: metC pphA c-di-GMP mrcA peptidoglycan DD- a mature peptidoglycan with endopeptidase: 3-oxo- with reduced L- carrier protein] adenosyltranferase]- nadD 5-phosphate pyruvate formate- phosphate 3- glucose and glucose-1-phosphate degradation phosphate D-glucopyranose 6-phosphate D-glucopyranose sn-glycerol sn-glycerol an N-modified peptidyl-lysine N- a [protein]- phosphosugar reductase: geranyl synthase: menD sulfanyl-L-cysteine (S)-4-amino-5-oxopentanoate malate dehydrogenase: D-allulose-6- a 2'- exodeoxyribonuclease: tRNA pyruvate γ endotransglycosylase: pbpG glutaryl-[acp] AI-2 cysteine residues cob(I)inamide S-ribosyl-L-homocysteine precorrin-2 lyase: pflB aldolase: fucA L-fuculose 1-phosphate L-Ala-D/L-Glu S-formylglutathione 3-phosphate 3-phosphate amino acid acetyltransferase: L-tyrosine phosphatase: rclA YehE peptidoglycan DD- transpeptidase: mrcB (L-alanyl- -D-glutamyl-meso- diphosphate 2-succinyl-5-enolpyruvoyl- L-homocysteine cysteine :[Thil sulfur- sulfur carrier 1-deoxy-D-xylulose dehydrogenase ldhA maltodextrin epimerase: phosphate 3- deoxyribonucleoside [DNA] yqgF mltC methyl ester epimerase: ycjG hydrolase: yeiG [DNA] 0 carboxypeptidase: 2,6-diaminopimeloyl-D-alanyl- meso- protein cysteine] protein ThiS cobinamide protoporphyrinogen protoporphyrinogen NaMN nicotinamide 5-phosphate glutamate-1- pyruvate formate- sgbU phnO yigL Te peptidoglycan DD- 6-hydroxy-3-cyclohexene- (oxaloacetate- phosphorylase: L-rhamnulofuranose α-D-glucopyranose 1-phosphate epimerase: 5'-monophosphate 6 reductase: farnesyl protoheme nicotinamidase: precorrin-2 lyase: tdcE maltodextrin S-formylglutathione a [protein]-N - mrcB transpeptidase: mrdA D-alanine) pentapeptide diaminopimelic HrpB 1-carboxylate cobalamin- sulfurtransferase: adenylyltransferase: adenosyltransferase: dehydrogenase: hemG oxidase: hemG reductoisomerase: dxr S-ribosylhomocysteine semialdehyde 2,1- malP L-ribulose 5- glycolaldehyde L-fuculose- alsE phosphosugar a mature fabG diphosphate pncA decarboxylating) phosphorylase: DHAP L-alanyl-L-glutamate hydrolase: frmB a 2'- acetyl-L-lysine a mature acid-D-alanyl YehD independent an apo-[c-type iscS thiF btuR aminomutase: hemL dehydrogenase: cysG (R)-lactate phosphate rhamnulokinase: a [DNA]-3'- phosphatase: D-alanyl-D-alanine a (3R)-3- synthase: ispA (1R,6R)-2- heme lyase: luxS : maeA malP phosphate deoxyribonucleoside a nascent peptidoglycan peptidoglycan peptidoglycan homocysteine cytochrome] with a [ThiI sulfur- a carboxy- MEP α-D-glucose- glycolaldehyde F6P hydroxyl carboxypeptidase: endopeptidase: hydroxyglutaryl- succinyl-6- nicotinate acetyl-CoA formate L-ribulose-5- rhaB phosphoglucomutase: aldolase: fucA formate phoA YfbL with D,D cross-links (meso- with (L-alanyl- strand (non- (2E,6E)-farnesyl transmethylase: binding and adenosylcobinamide AI-2 5-aminolevulinate sirohydrochlorin 1-phosphate dehydrogenase: alanylglutamate 5'-monophosphate dacA dacB hydroxy-2,4- a dislufide bridge carrier protein]-S- adenylated-[ThiS phosphoribosyltransferase: phosphate 4- L-rhamnulose pgm D-mannitol γ-D-glutamyl- reducing terminus) [acp] methyl ester diphosphate metE reduction: thiol:disulfide 2-C-methyl-D- phosphatase: yihX aldA α diaminopimelate containing) YeaV cyclohexadiene- sulfanyl-L-cysteine sulfur-carrier protein] protoporphyrin IX (S)-malate 2-O- -mannosyl-D- dipeptidase: pepD D-alanyl-D-alanine meso-2,6- 3-hydroxyglutaryl- ccmC cobinamide pncB erythritol 4-phosphate porphobilinogen sirohydrochlorin citrate α epimerase: 1-phosphate (S)-lactaldehyde YcbV all-trans- 1-carboxylate cobalamin- oxidoreductase: D-glyceraldehyde phosphate acetaldehyde formate -D- sugar DHAP glycerate degradation carboxypeptidase: peptidoglycan peptidoglycan [acp] methyl chorismate ccmD ccmE kinase: cobU nicotinate cytidylyltransferase: synthase: hemB ferrochelatase: cysG fumarase: fumE synthase: gltA maltotriose sgbE glycolate diaminopimeloyl- octaprenyl- ccmG carboxy-adenylated- ferrochelatase: acetyltransferase: dehydrogenase: hydrogenlyase glucopyranose phosphatase: ybiV N 6 -(3-methylbut- an O 6 - a [chaperone- (3R)-3- a [glutamine- microcin B17 precursor a [glutamine dacD tetrapeptide, tetrapeptide, ester synthase: menH dependent 3-phosphate rhamnulose- D-glucopyranose 6-phosphate 2-O-(6-phospho- a [protein]- carbamoyl β-aspartyl queuosine at D-sorbitol a supercoiled D-alanine) an apo-[c-type tyr [ThiS sulfur- ispD fumarase: fumD complex: fdhF 1-phosphate L-ribulose-5- glu ala c-di-GMP a protein with glutathione hydroxybutanoyl- a cis- sn-glycerol [HypE] C-terminal synthetase]- an mRNA L-cysteinylglycine peptide containing L-methionine- ATP YhdV a mature peptidoglycan glycan chain 1 glycan chain 2 dehydratase: fabZ diphosphate (1R,6R)-6-hydroxy-2- methionine a heme(III)-bound 1-deoxy-D- adenosyl-cobinamide 5,6-dimethylbenzimidazole hemH (2R,4S)-2-methyl-2,4- siroheme eutD adhE maltotriose 1-phosphate sugar α-D-mannosyl) a sulfurated [sulfur carrier] 2-en-1-yl)- methylguanine L-cysteine ADP]-[disordered- H O ATP DL-allothreonine dipeptide glu position 34 synthetase]-O 6-phosphate duplex DNA D-alanyl-D-alanine tetrapeptide chorismate cytochrome] 4-(cytidine 5'- porphobilinogen citrate phosphate 4- a disulfide bond 2 vaccenoyl-[acp] phosphate (S)-S-oxide synthase: ispB succinylcyclohexa-2,4- carrier-protein] phosphate fumarase A: fumA hycE hycB hycG glucosidase: adenosine 37 in tRNA c-di-GMP in DNA form scaffold CoA 3-phosphate L-cysteine L-tyrosine ribosome- azole residues Asp 4 -(5'-adenylyl) 5' to 3' ATP- Ap A with D,D cross-links (meso- synthase: CcmCDE complex dihydroxydihydrofuran-3-one phosphate acetaldehyde aldolase: rhaD phosphatase: yidA -D-glycerate of a tRNA sorbitol-6- methionine- 4 carboxypeptidase: YghB lyase: ubiC with reduced L- xylulose-5- sulfurtransferase: thiI protoheme diphospho)-2-C- epimerase: 2-O-(6- non-specific ion/solute non-specific ion/solute a (2E)-enoylglutaryl- all-trans- diene-1-carboxylate metH 2-iminoacetate nicotinate- fumarase B: fumB dehydrogenase: hycF hycC hycD malZ phosphodiesterase: pdeC protein] complex dependent mRNA -L-tyrosine phosphatase: dependent synthetase: diaminopimelate containing) LamB YfcR release of phosphate cobinamide-P methyl-D-erythritol hydroxymethylbilane citrate hydro- acetyltransferase: pta araD phosphosugar glucokinase: glk ribose phospho-α- S-sulfoxide dacC maltose [acp] methyl ester octaprenyl a reduced thioredoxin cysteine residues nucleotide--dimethylbenzimidazole fumarase C: fumC D-gulosides interferase: yafO cysteinylglycine isoaspartyl DNA entE maltose 4-hydroxybenzoate o-succinylbenzoate synthase: dxs synthase: thiH guanylyltransferase: 4-(cytidine 5'- synthase: hemC lyase: acnB eutE phosphoglucomutase: phosphatase: yigL phosphorylation mannosyl)- isopentenyl- cyclic di-GMP O-6-methylguanine- glutaredoxin: acyl-CoA acyl-acp:sn- carbamoyl- glutamine synthetase allothreonine microcin B17 glutamyl-Q hxpB reductase: [+ 3 isozymes] heme-bound thiol:disulfide a thiocarboxylated- maltose D-xylulose DHAP (S)-lactaldehyde chitobiose degradation conversion to dipeptidase: pepN dipeptide enoylglutaryl- diphosphate synthase: menC met AIR cobU phosphoribosyltransferase: cobT bis(guanylyl molybdopterin) cofactor sulfurylation pgm phosphodiesterase: pdeF grxC thioesterase: -[HypE] adenylyltransferase: mRNA acetaldehyde- precursor glutamine sugar helicase: bisC Ap A CcmE: oxidoreductase: 1-deoxy-D-xylulose [ThiS sulfur- diphospho) fumarate CO H 5-phosphate D-glycerate adenosine tRNA DNA non- glycerol-3- tRNA(Asp) 4 FtsN [acp] methyl thioredoxin:disulfide 2-iminoacetate (2R,4S)-2-methyl-2,3,3,4- preuroporphyrinogen cis-aconitate acetyl phosphate 2 2 β-D-ribopyranose D-glucosides ligase: hypF glnE interferase: higB cysteinylglycine hydrolase: recD synthetase: a nascent peptidoglycan HsrA ccmB ccmA ccmH 5-phosphate carrier protein] adenosylcobinamide- α -2-C-methyl- amylomaltase: D-glucopyranose N,N'- hydrolase: methylthiolase: c-di-GMP methyltransferase: chaperonin protein- yciA phosphate 1-O- lyase (glycine- protease: synthetase: synthetase phosphatase: methionine 4-hydroxybenzoate methionine oxidoreductase: trxA phosphomethylpyrimidine lipoate -ribazole 5'-phosphate tetrahydroxytetrahydrofuran acetaldehyde dipeptidase: pepB iaaA γ cobalamin ester 2-succinylbenzoate an apo-[c-type D-erythritol fumarate malQ D-ribose a D-guloside mngB miaB phosphodiesterase: pdeH ada molecular acyltransferase RNase: yafQ forming): glyA tldD tldE gluQ deadenylase: ybiV helicase: sulfoxide lysU with (L-alanyl- -D-glutamyl- YqiI octaprenyltransferase: GDP D-threo- acetate diacetylchitobiose disulfide (R)-3- reductase: fabI adenosyltransferase: a heme(III)-bound cytochrome]-- synthase: thiC biosynthesis and cys uroporphyrinogen- reductase: frdA ethanol glucose pyranase: D-guloside 3- D-glycerate c-di-GMP a [HypE RNase: relE cysteinylglycine isoaspartyl glnE dnaB meso-2,6-diaminopimeloyl- outer 1-deoxy-D-xylulose kinase: ispE 6'-phosphate O 6 -alkylguanine- chaperone reductase hydroxybutanoyl- (glycerol-3- a [glutamine sorbitol-6- reductase: Ap4A cob(I)inamide cob(I)inamide ubiA o-succinylbenzoate--CoA metK CcmE protein incorporation I thiamine diphosphate salvage II III synthase: hemD frdB frdC frdD isocitrate hydro- kinase: ackA D-glucopyranose rbsD dehydrogenase: dipeptidase: pepA dipeptidase: D-alanine) tetrapeptide membrane a glutaryl-[acp] a [reduced DsbD protein] CcmH disulfide cobalamin 5'- 2-phospho-4-(cytidine dehydrogenase: dehydrogenase: gcd N 6 -(3-methylbut-2-en- phosphodiesterase: pdeR ATPase: hscA (glutathione) CoA phosphate hydrogenase synthetase]-O sequence-specific phosphatase: 5' -> 3' msrA cob(I)alamin cob(I)alamin HMP-P 5-phosphate:thiol L-cysteine:[protein lyase: acnB L-arabinose N,N'- DNA- glutamyl- ligase: menE 5'-diphospho)-2-C- ycjQ glycerate an unsulfurated 4 cysteinylglycine acetaldehyde iadA microcin B17 YiaV transport YiaA methyl ester sulfurtransferase: phosphate acetate adhP sedoheptulose degradation I diacetylchitobiose D-ribose a 3-dehydro- 5'-deoxyadenosine 1-yl)-2-(methylsulfanyl) met c-di-GMP alkyltransferase: : grxA thioesterase: tesB acyltransferase) maturation -(5'-adenylyl) endoribonuclease gly a peptide queuosine at a [glutamine- hxpA helicase: 4-hydroxy-3- SAM thiol-disulfide an octanoyl-[acp] 4-amino-2-methyl-5- cysteine] uroporphyrinogen-III succinate D-glucono-1,5-lactone 2-kinase: dipeptidase: pepD met L,D L,D- L,D- complex 4-(2'-carboxyphenyl) holocytochrome thiG synthase: methyl-D-erythritol D-threo-isocitrate ethanol bisphosphate bypass glucokinase: pyranase: D-guloside adenosine 37 in tRNA [sulfur carrier] phosphodiesterase: dosP : plsB protein] C- -L-tyrosine GhoS: ghoS position 34 ADP synthetase]- dinG 3-oxo- octaprenylbenzoate phosphomethylpyrimidine octanoyl sulfurtransferase: 6'-phosphate glxK ogt a [disordered- an [Fe-S cluster glutathione:protein sugar carboxypeptidase: transpeptidase: ldtD YdeS exchange: c synthase: ccmF pyrimidinemethanol terminal S- Asp a single transpeptidase: ldtE -4-oxobutyryl-CoA transferase: cobS 2-C-methyl-D- preQ biosynthesis dehydrogenase: glk L-arabinopyranose monodeacetylase: fucU 3-dehydro- [+ 2 isozymes] form [Fe-S] cluster biosynthesis disulfide [+ 2 isozymes] a proteinogenic of a tRNA L-tyrosine phosphatase: pimeloyl-[acp] 3-octaprenyl-4- dsbD kinase: thiD iscS 0 D-sedoheptulose (R)-3- stranded DNA ldtD a mature peptidoglycan partially partially 1,4-dihydroxy-2- 2-[(2R,5Z)-2-carboxy- a [lipoyl-carrier hydroxymethylpyrimidine erythritol 2,4- isocitrate adhE L-arabinose gluconolactonase β-D-ribofuranose glycerate carboxamidyl- asp L,D- methyl ester hydroxybenzoate a CcmG protein a CcmE-[c-type lipB 7-phosphate chbG D-guloside 4- 5'-phosphoguanylyl(3'->5')guanosine scaffold protein] chaperone]-ATP reductase: grxB hydroxybutanoate 1-cis-vaccenoyl- an mRNA fragment amino acid yidA a nascent peptidoglycan γ deacetylated deacetylated 4-methylthiazol-5(2H)- 6 kinase: thiD L-cysteine cyclodiphosphate dehydrogenase: icd isomerase: 2-kinase: a [protein]-S- L-cysteine cys gly transpeptidase: ldtD with (L-alanyl- -D-glutamyl- MzrA synthase: fabB naphthoyl-CoA HMP-PP protein] N - adenosylcobalamin epimerase: a guanine in DNA sn-glycerol- phosphosugar TufA a nascent peptidoglycan with with (L-alanyl-γ-D-glutamyl- poly-β-1,6- PgaA poly-β-1,6- decarboxylase: ubiD with reduced cytochrome--CcmH ylidene]ethyl phosphate hydroxymethylpyrimidine desulfurase: sufS synthase: ispF ethanol sedoheptulose- D-glucopyranose araA garK methyl-L-cysteine meso-2,6-diaminopimeloyl- (2E,6E)-farnesyl diphosphate synthase: menB octanoyl-L-lysine 5'-phosphate GTP D-gluconate GlcN6P-GlcNAc ycjR 3-phosphate (L-alanyl-γ-D-glutamyl-meso- meso-2,6-diaminopimeloyl- 3-oxopimeloyl- cysteine residues disulfide] complex 2-oxoglutarate 7-phosphate 6-phosphate trehalose degradation II (cytosolic) a protein with phosphatase: a nascent peptidoglycan D-alanine) tetrapeptide N-acetyl-D- N-acetyl-D- YbgD 2-octaprenylphenol lipoyl kinase: pdxK bis(guanylyl an [L-cysteine desulfurase]- 2-C-methyl-D-erythritol- L-ribulose a 3-dehydro- 2-phospho- GSSG glycine) tetrapeptide [acp] methyl 1,4-dihydroxy-2- thiamine adenosylcobalamin 5-(2-hydroxyethyl) GTP kinase: pfkA reduced L- yigL with L,D cross links (meso- 2,6-diaminopimelate) tripeptide glucosamine glucosamine all-trans- synthase: molybdopterin) cofactor S-sulfanyl-L-cysteine 2,4-cyclodiphosphate D-xylose D-glycerate naphthoyl-CoA thiol:disulfide -4-methylthiazole HMP-P cyclohydrolase ribulokinase: monoacetylchitobiose- D-ribofuranose D-glucoside cysteine residues phosphosugar diaminopimelate containing) ester octaprenyl- phosphate lipA 5'-phosphate D-sedoheptulose α α degradation I YdfJ 2-octaprenylphenol 1,4-dihydroxy-2- superpathway of tetrahydrofolate biosynthesis oxidoreductase: bis-MGD cofactor 1-hydroxy-2- 7,8- I: folE , -trehalose 6-phosphate D-glucoside 3- iron- synthase: fabF synthase: thiE a [lipoyl-carrier phosphatase: cobC hydroxyethylthiazole 1,7-bisphosphate araB ribokinase: phosphatase: YidX 6-hydroxylase: ubiI diphosphate naphthoyl-CoA ccmG chaperone: fdhD dihydroneopterin dehydrogenase: catecholate protein]-N 6 -[(R) phosphomethylpyrimidine methyl-2-(E L-ribulose 5- D-xylose hydrolase: chbF phoA a mature peptidoglycan with a mature peptidoglycan iron(III)-[N-(2,3- iron(III)-[N-(2,3- a 3-oxopimeloyl- 3-(all-trans synthase: ispB adenosylcobalamin kinase: thiM 3'-triphosphate D-mannose lactose degradation III rbsK ycjS YjbE hydrolase: menI superpathway of coenzyme A biosynthesis I (bacteria) kinase: thiD a [bis(guanylyl molybdopterin) )-butenyl 4- superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass sedoheptulose trehalase: treF xylose D-sorbitol (L-alanyl-γ-D-glutamyl-meso- with (L-alanyl-γ-D-glutamyl- dihydroxybenzoyl) outer dihydroxybenzoyl) [acp] methyl ester -octaprenyl) flavin biosynthesis I (bacteria and plants) -dihydrolipoyl]- 4-methyl-5-(2- [bis-MGD cofactor 6-carboxy-5,6,7,8- phosphate D-ribofuranose a mature peptidoglycan all-trans-octaprenyl GTP thiamine phosphate cofactor chaperone]- diphosphate bisphosphate degradation I isomerase: D-glucosamine N-acetyl-D- 2,6-diaminopimelate) tripeptide meso-2,6-diaminopimeloyl- -L-serine membrane -L-serine benzene-1,2-diol 1,4-dihydroxy-2-naphthoate a CcmH-CcmG disulfide a c-type cytochrome L-lysine phosphooxyethyl) chaperone]-bis-MGD tetrahydropterin L-ribulose-5- 5-phosphate a D-glucoside with L,D cross-links (meso- YhbX 3-oxo- diphosphate a 5,10- HMP-PP S-sulfanyl-L-cysteine synthase: ispG aldolase: fbaA lactose xylA 6-phosphate glucosamine glycine) tetrapeptide trimer] complex transport trimer] complex 2-octaprenyl-6- thiamine 3-methyl-2-oxobutanoate thiazole synthase: queD D-glucopyranose 6-phosphate D-mannopyranose β-D-glucopyranose α-D-glucopyranose phosphate 4- diaminopimelate containing) pimeloyl-[acp] GTP methylenetetrahydrofolate (E)-4-hydroxy-3- isopentenyl- lactose D-xylulose a [ribosomal L-alanyl-γ-D- 1-cis-vaccenoyl- (S)-3- 2-dehydro-3-deoxy- a [disulfide-bond YgcG complex I hydroxyphenol D-mannose PTS epimerase: a peptidoglycan dimer a cis- DNA containing a 5'-phospho- a [protein] uridylyl- L-methionine- methyl ester cyclohydrolase GTP monophosphate bis-MGD cofactor molybdenum cofactor biosynthesis methylbut-2-en- diphosphate:NAD(P)+ 6-carboxy-5,6,7,8- galactohydrolase: trehalose degradation I (low osmolarity) a sulfurated protein S12] glutamyl-meso-2,6- F6P sn-glycerol- hydroxybutanoyl- an unsulfurated wound RNA oxalate acetyl-CoA a uridine in tRNA ATP a protein carrier protein] HMP-PP methylase: ubiG 1,4-dihydroxy- thiamine glucose-6-phosphate D-erythrose permease: manZ with pentapeptide H O a base with lesion cys D-arabinonate 3-sulfino-L-alanine [DNA] C-terminal glu YbeQ thiol:disulfide kinase: thiL chaperone: fdhD tetrahydropterin DHAP araD lacZ xylulokinase: [sulfur carrier] 89 vaccenoyl-[acp] 2 [sulfur carrier] [protein PII-1] (R)-S-oxide β-D-fructose 1,6- a mature peptidoglycan a peptidoglycan a [protein]- reductase: 2-naphthoate I: folE 3-methyl-2-oxobutanoate 1-yl diphosphate oxidoreductase: ispH isomerase: pgi 4-phosphate β-D- L-aspartate stems (meso- diaminopimeloyl- UDP-N-acetyl- 3-phosphate CoA RNA helicase: rhlB tRNA- L-glutamate with reduced L- HMP-PP (n) 2-methoxy- oxidoreductase phosphate manY manX D-xylulose ATP-dependent methionine tripeptide FAD 3'-AMP 5'Ap3A fabG 7,8- hydroxymethyltransferase: 7-carboxy-7- D-mannopyranose xylB melibiose degradation α α D-alanine α RNA helicase: dbpA dihydrouridine 16 cysteine residuesprotein hydrolase: bisphosphate (meso-DAP containing) L-threonine YnaJ 6-(all-trans- octaprenyltransferase: GTP cyclohydrolase thiamine diphosphate synthase: thiE molybdate glucose-6-phosphate galactopyranose fructose degradation , -trehalose 6-phosphate diaminopimelate -D-muramate Clp protease: sulfoxide fructose-1,6- DigH a (3R)-3- dihydroneopterin CcmG: ccmG panB sulfo-bis(guanylyl deazaguanine 5-phosphate fructose-6- DNA 2-dehydro- acetyl- DNA 5' disulfide cof D-xylose XylFGH D-xylose crosslinked to 3'AMP octaprenyl)phenol menA II: ribA superpathway of pyridoxal 5'-phosphate biosynthesis and salvage IPP isomerase: kduI 6-phosphate D-xylulose containing) acyl-CoA ATP-dependent synthase: dusC [protein- clpP clpA clpX reductase: biphosphate molybdopterin) cofactor D-glucopyranose protein 1-acylglycerol- containing L-cysteine 3-deoxy-D- cysteine sulfinate CoA:oxalate adenylyl ribosomal murein lipoprotein phosphatase: phoA hydroxypimeloyl- 2-octaprenyl-6- 3'-triphosphate molybdate ABC synthase: queE mannose-6- 5-phosphate β-D-fructofuranose melibiose phosphate RNA helicase: deaD tRNA- oxidase HMP-PP peptidoglycan lytic FAD:protein a CcmH protein 2,5-diamino-6-(5-phospho-D- dimethylallyl- methylthiotransferase: UDP-N-acetylmuramate:L- 3-phosphate O- thioesterase: desulfurase: pentonate desulfinase: sufS protein S6 PII-1-UMP] protease: msrB phosphatase: P 1 ,P 3 -bis(5'- StfQ [acp] methyl ester dihydroneopterin thiamine phosphate transporter: cysA 7-carboxy-7- F6P trehalose-6-phosphate aldolase: fsaB a base CoA- transferase: (quinone) exotransglycosylase: mltF adenosine 3'- methoxyphenol 4- with reduced 2-dehydropantoate D-erythrose diphosphate:NAD(P)+ phosphate glucokinase: 1-phosphate α-galactosidase: rimO alanyl-γ-D-glutamyl-meso acyltransferase: yciA sufS ATP-dependent cysteine sulfinate dihydrouridine modification: deuridylylation: clpP clpX hydrolase: D-xylose XylE D-xylose phoA FMN 3-hydroxypimeloyl- demethylmenaquinol-8 triphosphate ribosylamino)pyrimidin-4(3H)-one asp 1-phosphofructokinase: hydrolase: treC fructose-6- with lesion aldolase: yagE transferase: rtcA methionine- a [disulfide-: dsbB peptidoglycan nucleotidase: cpdB adenosyl) MdlB hydroxylase: ubiH cysteine residues 4-phosphate cysW cysU cysP oxidoreductase: ispH isopentenyl- deazaguanine isomerase: manA glk melA -diaminoheptanedioate- RNA helicase: srmB synthase: dusB glnD nudJ peptidoglycan lytic transferase: [acp] methyl ester diphosphatase: thiamine ∆ fructose-1,6- yihG (S)-3- hydrolase: cysteine 2-dehydro- desulfinase: csdA yfdE rimK ATP-dependent (R)-sulfoxide bond carrier fructose-1,6- triphosphate 2-methoxy-6-all diaminohydroxyphosphoribosylaminopyrimidine 2-dehydropantoate molybdate ABC diphosphate - 7-cyano-7- β fruK D-galactopyranose phosphate exotransglycosylase: slt meso- ftp nucleoside 3'- dehydratase: fabZ demethylmenaquinone aspartate 1- D-erythrose- bisphosphatase: yggF D-glucopyranose -D-fructose 1,6- a [ribosomal D-alanine ligase: mpl hydroxybutanoyl- desulfurase: ATP-dependent 3-deoxy-D- tRNA- Clp protease: reductase: protein] carrying HMP-P bisphosphatase: hydrolase: YeeJ trans-octaprenyl- nudB deaminase: ribD monophosphate transporter: sbp isomerase: idi F6P glucokinase: glk aldolase: fsaA acyl-[acp]:1-acyl- mug an adenosine- diaminopimelic monophosphate methyltransferase: ubiE 7,8- 2-reductase: ilvC 4-phosphate deazaguanine 6-phosphate bisphosphate D-glucopyranose 5'-deoxyadenosine protein S12]-3- an unsulfurated CoA iscS RNA helicase: rhlE dihydrouridine clpP clpA msrC a disulfide bond yggF peptidoglycan lytic ushA a (2E)-enoylpimeloyl- 1,4-benzoquinol decarboxylase: kinase: thiL tetrahydromonapterin molybdopterin fructose 1,6- 6-phosphofructokinase: D-glucopyranose 6-phosphate met sn-glycerol-3- pentonate 5'-diphospho- a [protein] C- UMP YhhJ acid protein phosphatase: aphA YhjY dihydroneopterin 5-amino-6-(5-phospho- 2-dehydropantoate dehydrogenase: cysW cysU cysA synthase: queC methylsulfanyl- [sulfur carrier] a peptidoglycan dimer L-alanyl-γ-D- an unwound RNA sulfite synthase: dusA α exotransglycosylase: mltD [acp] methyl ester 2-octaprenyl- panD biosynthesis bisphosphatase: ybhA pfkA UDP-N-acetylmuramoyl- phosphate 2-O- thioesterase: tesB a DNA containing aldolase: yjhH ala acetate oxalyl-CoA a 5,6- 5'-[DNA] terminal -L- PII-1 serine met fructose-1,6- amidase: dpaA a [protein]-FMN- Psd menaquinol-8 3'-phosphate D-ribosylamino)uracil 2-reductase: panE epd transport of molybdopterin 89 with pentapeptide stem glutamyl-meso-2,6- γ D-glyceraldehyde a modified α peptidoglycan lytic AMP 6-methoxy-1,4- thiamine diphosphate DMAPP preQ fructose-1,6- 6-phosphofructokinase: Detoxification L-aspartate L-alanyl- -D- dihydroxyacetone acyltransferase: an apurinic/ dihydrouridine glutamate- - protease: clpP bisphosphatase: L-threonine adenosine enoylpimeloyl- dihydroneopterin 5-amino-6-(5- β 4-phospho- molybdate: modC adenylyltransferase: 0 (meso-diaminopimelate diaminopimeloyl- 3-phosphate nucleobase a sulfurated exotransglycosylase: mltC ADP AMP benzoquinol adenosylcobalamin -alanine (R)-pantoate bisphosphatase: glpX pfkB glutamyl-meso-2,6- plsC (S)-3- apyrimidinic site ala in tRNA L-glutamate a peptide glpX [acp] methyl monophosphate phosphoribosylamino) D-erythronate modB modA mog Fatty Acid and Lipid Degradation containing) D-alanyl-D-alanine [sulfur carrier] glycolaldehyde peptidoglycan lytic a peptidoglycan methylase: salvage from cobalamin GTP fructose-1,6- diaminopimeloyl- hydroxybutanoate pyruvate fructose-1,6- a murein ester dephosphorylase uracil reductase: ribD superoxide DgcI exotransglycosylase: mltB internal segment NlpE ElfG ubiE erythronate- GTP molybdopterin bisphosphatase: fbp arsenic detoxification (yeast) arginine dependent D-alanine 1,2-bis-cis- bisphosphatase: fbp lipoprotein reductase: fabI pantothenate molybdate oleate β-oxidation Aldehyde Degradation radicals [+ 2 isozymes] with (L-alanyl- YbeX 6-methoxy-3- D-erythro-7,8- chorismate 5-amino-6-(5-phospho- cob(I)alamin 4-phosphate cyclohydrolase adenine dinucleotide acid resistance vaccenoyl- F6P NAD de novo biosynthesis synthetase: panC fatty acid β-oxidation I (generic) degradation γ-D-glutamyl- a pimeloyl-[acp] methyl-2-all- dihydroneopterin D-ribitylamino)uracil dehydrogenase: I: folE β-D-fructose 1,6-bisphosphate L-aspartate degradation phosphatidate I (from aspartate) 4-amino-4- molybdopterin biosynthesis 7,8-dihydroneopterin fructose-bisphosphate arsenate meso-2,6- methyl ester trans-octaprenyl- 5-amino-6-(5- pdxB 3'-triphosphate molybdopterin II (anaerobic) oleate superpathway of methylglyoxal degradation superoxide a mature peptidoglycan GlcNAc-1,6-anhMurNAc- dihydroneopterin deoxychorismate aldolase: fbaB a (3Z)-alk-3- L-lactaldehyde arg (n) diaminopimelate) 1,4-benzoquinol phospho-D- (R)-pantothenate molybdotransferase: superoxide (meso-DAP containing) L-Ala-γ-D-Glu-DAP-D-Ala YadL pimeloyl-[acp] aldolase: folB cob(II)alamin (3R)-3-hydroxy-2-oxo- dihydroneopterin DHAP enoyl-CoA degradation (aerobic) 4 β N-(4- α AraJ RsxC asp synthase: moeA fructose bisphosphate fatty acyl-CoA arsenate arginine a 5-[(methylamino) a thymine a [protein]- an O - a reduced 1-myristoyl- 1-myristoyl- poly- -1,6- DNA with L-glycero-L-galacto- a CDP- GDP- -D- tripeptide methyl ester 2-octaprenyl- D-ribulose 5-phosphate ribitylamino)uracil 4 phosphooxybutanoate cys asp dismutase: glutathione NADPH H + a quinone FMN NADH H + isobutanal ADP ATP YbgQ triphosphate 2'- ∆ 3 2 methylglyoxal decarboxylase, methyl]-2- methylthymine + + ferredoxin [iron- a palmitoleoyl-[acp] S-sulfo-L-cysteine sn-glycerol a myristoyl-[acp] N-acetyl-D- adenine:7,8- aminobenzoyl) octuluronate- mannose a protein L-aspartate 6-(hydroxymethyl) pabB pabA pantothenate aldolase: fbaA synthetase: fadD -cis-∆ sodB reductase: glycol in DNA L-cysteine NADP H sn-glycerol xanthosine diacylglycerol GMP 3-methyl-6- phosphatase: yigB D-glyceraldehyde Amine and Polyamine Biosynthesis (S)-lactaldehyde geranyl 34 esterase: bioH -7,8-dihydropterin pyruvate phosphohydroxythreonine epimerase: folX triose-phosphate degradative: adiA selenophosphate thiouridine in DNA sulfur] cluster 3-phosphate 3-phosphate glucosamine dihydro-8- -L-glutamate 1-phosphate isobutyraldehyde oxidase: nadB 4-amino-4- 3,4-dihydroxy- kinase: coaA L-cysteine:[protein L-aspartate:succinate short chain -trans- arsC ATP- 4-amino-4- α-D-Kdo-(2->4) lipid A-core 4,6-pyr-α-D-Gal-(1->4) α ε methoxy-1,4- 5-amino-6-(5- 3-phosphate aminotransferase: serC MoO -molybdopterin cofactor lactaldehyde superoxide agmatine diphosphate in tRNA oxoguanine reductase: yghA N ,N -diacetyl-lysyl- L-histidinol 2-iminosuccinate 2-amino-4-hydroxy-6- deoxychorismate 2-butanone- cysteine] 7,8-dihydromonapterin 2 isomerase: tpiA acyl-CoA enoyl-CoA lactoylglutathione methylglyoxal methylglyoxal GDP- dependent phosphate α -α-D-Kdo-(2->6) triphosphate CDP-glycerol a pimeloyl-[acp] benzoquinol cob(II)alamin- ATP antiporter: dcuB dehydrogenase: dismutase: bifunctional 4 NADPH- CDP- FMN Ap A deoxy- -L- oligosaccharide (E. -β-D-GlcA-(1->3)-2- D-alanyl-D-alanine phospho-D- superpathway of arginine and polyamine biosynthesis O -methylthymine- mismatch isobutyraldehyde 3 phosphate YhhZ DcuD hydroxymethyldihydropteridine 4-phosphate (R)-4'-phosphopantothenate 4-phosphooxy- sulfurtransferase: triphosphate glutathionylspermidine synthetase: fadK isomerase: lyase: gloA reductase reductase: yqhD a [glutaredoxin]- ferredoxin- acyl-[acp]:1-acyl- S-sulfo-L- acyl-[acp]:1-acyl- p-aminobenzoyl- L-glycero- mannose HslVU arsenate ABC arsenate -lipid A (E. coli) hydroxylase: quinolinate aminodeoxychorismate ribitylamino)uracil [corrinoid 1-deoxy-D- succinate:L-aspartate aldA sodA arsenous acid thymine dependent diacylglycerol reductase: synthetase: arabinopyranosyl coli K-12 core type) O-Ac-α-D-Gal-(1->3) L-histidinol- GTP hydrogen DNA + xanthosine reductase: ybbO GMP 8-amino-7- diphosphokinase: folK synthase: ribB L-threonine iscS molybdopterin- biosynthesis D-glyceraldehyde 3-phosphate fadB (NADPH- methylglyoxal glutathione tRNA 2- NADP sn-glycerol-3- cysteine sn-glycerol-3- glutamate L-galacto- mannosyl lysU protease: transporter ditrans,octacis -α-L-Fuc-(1->4)-3- ubiF synthase: lyase: pabC phosphatase: ybjI adenosyltranferase] xylulose-5- antiport: dcuA oleoyl-CoA (S)-lactate peroxide glycol DNA methyltransferase: ogt quinone nucleosidase: diphosphatase: rutF nucleosidase: CDP- phosphate YeaY (7,8-dihydropterin- phosphopantothenoylcysteine synthase (R)-S- dependent) reductase: yeaE disulfide selenouridine reductase: phosphate 2-O- reductase: phosphate 2-O- adenine hydrolase: octuluronate- isobutyraldehyde hydrolase: hslU hslV D-alanyl-D-alanine triphosphate oxononanoate nadA 1-deoxy-L-glycero- phosphate 4-hydroxythreonine- L-cysteine glu dodecenoyl- glycosylase: reductase: nfsA cdh FMN -undecaprenyl O-Ac-α-L-Fuc-(1->3) phosphatase: 3-demethylubiquinol-8 6-yl)methyl synthetase: dfp glutathione spermidine glyceraldehyde- lactoylglutathione L-lactate catalase: synthase: selU O-4-methylthymine- fpr grxA glycosylase: abgB abgA rihC 1-phosphate reductase: dkgA ppnN gmm carboxypeptidase: glycerol synthase: bioF 4-aminobenzoate ARP synthase: 4-phosphate desulfurase: adenylyltransferase: GTP 3',8'- citrate lyase activation asp acyl-CoA CoA D- methylglyoxal nth acyltransferase: acyltransferase: a peptide phosphate -α-D-Glc-PP-Und phosphatase: phoA diphosphate tetrulose 4-phosphate dehydrogenase: adeD quinone partially aldolase: ydjI reductase: YnaM dacD hydrolase: HlyE YedI quinolinate (R)-4'-phosphopantothenoyl- dxs dehydrogenase: sufS moeB 7,8-dihydromonapterin 3-phosphate isomerase: hydroxyacylglutathione reductase: dkgA DNA plsC plsC mutY isobutyraldehyde 5'Ap3A phoA (8S)-8-amino-7- 3-demethylubiquinone- cob(I)alamin- pyridoxal cyclase: moaA N-acetylglutamate dehydrogenase: (S)-lactaldehyde reductase: nfsB acetate deacetylated poly- CMP a 1,2-diacyl- fre ushA histidinol- prenylated FMNH biosynthesis L-cysteine pdxA an [L-cysteine a carboxy-adenylated 3'-dephospho- dehydrogenase: gapA fadJ 3-hydroxybutyryl- hydrolase: gloC lldD catalase: a 5-methylaminomethyl- (2E)-3,7- methyltransferase: an oxidized reductase: yahK D-ribose 5- D-alanyl-D-alanine oxononanoate dihydropteroate 2 (8S)-3',8-cyclo-7,8- synthase: argA glutathionylspermidine fadE methylglyoxal a [DNA]-3'-α,β- β D-ribofuranose xanthine sn-glycerol 8 3-O- quinolinate 6,7-dimethyl-8- [corrinoid aspartate ammonia- CoA 34 a 5'-phospho- ada GSSG sulfite -1,6-N-acetyl- 4-aminobenzoate phosphate GDP D-mannose carboxypeptidase: phosphatase: pyridoxal 1-deoxy-D- 3-amino-1- desulfurase]-S- [small subunit of dihydromonapterin CoA synthetase: gss S-lactoylglutathione lactaldehyde reductase: dkgB katG 2-selenouridine dimethylocta- unsaturated thymine glycol ferredoxin [iron- NADPH 1-myristoyl-2- cys 1,2-dimyristoyl- a DNA containing glu aldehydo-L- 3-phosphate isobutanol guanine 7,8- methyltransferase: ubiG phosphoribosyltransferase synthase: folP ribityllumazine adenosyltranferase] 4'-phosphopantothenoylcysteine dihydroguanosine 13-DPG short chain a (2E)-2- pyruvate [DNA] D-glucosamine DHAP E. coli M hisB hydroxyacetone sulfanyl-L-cysteine molybdopterin synthase] reductase: folM lyase: aspA (2E,9Z)-octadecenoyl-CoA epimerase: fadJ in tRNA 2,6-diene-1-thiol + an apurinic/ + di-trans,octa-cis 4'-α-L-Ara4N-α- LPS dacC phosphate diphosphate cytidine YiaT transport diaminopelargonic cobalamin decarboxylase: dfp reductase: xylulose 5- 5'-triphosphate triphosphoribosyl- acyl-CoA enoyl-CoA enoyl-CoA hydrolase: yeiG dehydrogenase: methylglyoxal catalase: aldehyde sulfur] cluster palmitoleoyl- sn-glycerol a quinol NADP adenine arabinuronate FMNH NAD sn-glycerol (decarboxylating): nadC DMAPP synthase: ribE N-acetyl-L-glutamate 2 α histidinol pyridoxal pyridoxal ubiquinol-8 pdxI phosphate 1-phosphate cyclic pyranopterin dephospho-CoA 3-hydroxyacyl- hydroxyacylglutathione aldA reductase: gpr katE a [protein]-S- sn-glycerol 3-phosphate apyrimidinic site YhdP -undecaprenyl Kdo-(2->4)- - D-alanyl-D-alanine 3-phosphate YfcP of pyridoxal acid synthase: bioA 7,8- adenosyltransferase: 5,6,7,8- glutathionylspermidine phosphoglycerate enoyl-CoA synthetase: hydratase: a thymine in DNA di-trans,octa-cis 4'-phosphopantetheine synthase: citG CoA hydrolase: gloB methyl-L-cysteine 3-phosphate phosphate Kdo-(2->6)-[P4'- carboxypeptidase: (7R,8S)- NaMN dihydropteroate btuR monophosphate tetrahydromonapterin ammonium fumarate hydratase: fadJ fadK fadB O -undecaprenyl pyridoxine pyridoxine 5'- acetylglutamate kinase: pgk a 2,3,4- (S)-lactate 2 α dimethylallyl 6,7-dimethyl-8-(1-D-ribityl)lumazine adenosylcob(III) synthase: moaC 2'-(5''-triphospho- epimerase: -L-ara4N]-lipid A dacA diaminononanoate dihydrofolate kinase: argB cadaverine biosynthesis enoyl-CoA fatty enoyl-CoA (R)-lactate hydroxyacetone diphosphate YfiM nicotinate-nucleotide alamin-[corrinoid pantetheine- phosphate a thiocarboxylated α-D-ribosyl)-3'- glutamine a 2,3,4-saturated fadB saturated (3R)-3- dethiobiotin synthetase: folC diphosphate cyclic pyranopterin 3-phospho-D-glycerate hydratase: fadB acyl-CoA hydratase: an [RNA]-3'- a mechlorethamine 3-oxo-(9Z)- 1-palmitoyl- 1-palmitoyl- 1-(β-D methyl β-D-glucoside GDP-α-D- a [protein]- adenylyltransferase: riboflavin adenosyltranferase] phosphate pyridoxal synthase: [small subunit of dephospho-CoA fatty acid acyl-CoA hydroxyacyl-CoA L-lactaldehyde a uracil in DNA (I) + an ADP-sugar a ribonucleoside RNA D-xylonate pyrophosphatase: pyridoxamine N-acetylglutamyl- synthetase: glnA L-lactate menadione NADH H 2,3- RNA an acyl-CoA H O his15 α ε GfcD synthetase: pyridoxine phosphate synthetase: fadJ L-1,2-propanediol ribonucleoside- derived interstrand hexadecenoyl-CoA sn-glycerol a palmitoleoyl-[acp] sn-glycerol a myristoyl-[acp] ser ribofuranosyl) 6-phosphate 2 HPr-P BglG mannose L-tyrosine YaeF N ,N -diacetyl- ElfA acyl carrier protein metabolism nadD 7,8-dihydrofolate synthase: ribC adenylyltransferase: kinase: pdxJ molybdopterin synthase] apo-citrate lyase (S)-3-hydroxy-(9Z) dehydrogenase: degradation GTP diphosphate GMP nudJ kinase: pdxK phosphate lys 2,3-bisphosphoglycerate- a 2,3,4- D-lactate dehydrogenase: dehydrogenase: a 5'-hydroxy- 2',3'- DNA crosslink 3-phosphate 3-phosphate dihydroxybenzoate nicotinamide 5' -> 3' ribonucleoside- D-xylonate tyrosine lysyl-D-alanine D-ala bioD coaD pdxY phosphoribosyl- phosphoglycerate -octadecenoyl-CoA fadD a 2,3,4-saturated fadE (anaerobic) nicotinate adenine monoglutamate prenol pyridoxamine independent gln saturated (3S)-3- dehydrogenase lldD gldA ribonucleotide- cyclophosphate exoribonuclease: dehydratase: kinase: dimethylallyl riboflavin molybdopterin N-acetylglutamylphosphate lysine decarboxylase: ldcC fatty acyl CoA ADP-sugar β diphosphate GDP- GMP DgcQ dethiobiotin a holo acyl- dinucleotide pyridoxal kinase: pdxK dephospho-CoA phosphoglycerate mutase: gpmA 3-hydroxyacyl-CoA hydroxyacyl-CoA3-hydroxyacyl-CoA (quinone): dld 3'-[RNA] bifunctional 3-ketoacyl-CoA NADH methyl -D- yciV phosphate- acyl-CoA yagF wzc diphosphate 3'-dephospho-CoA pyridoxine synthase: reductase: argC lysine decarboxylase: cadA (S)-propane- (S)-lactaldehyde NM - acyl-[acp]:1-acyl- acyl-[acp]:1-acyl- diphosphatase: enterobactin nicotinamide reductase: mannose reductase: carrier protein + + adenosylcobalamin kinase: transferase: citX mutase: gpmM dehydrogenase: dehydrogenase: uracil DNA 5 thiolase: fadA dehydrogenase glucoside 6- dependent thioesterase: NAD NAD isopentenol pyrophosphatase: 5'-phosphate pyridoxamine moaD moaE cadaverine 1,2-diol L-1,2-propanediol interstrand synthase: riboside 3' -> 5' RNA nrdE nrdF hydrolase: D-xylonate protein- guaC α-Kdo-(2->4)- L-alanyl-γ-D- a peptidyl- riboflavin kinase: ribF pdxK a holo [citrate N-acetyl-L-glutamate fadB fadJ RNA glycosylase sn-glycerol-3- (quinone) sn-glycerol-3- nudE phosphate exonuclease: tesB PaeA an L-1- YdeQ biotin synthetase, synthetase, nudF dephospho-CoA oxidoreductase: acetyl-CoA C- entB entD exonuclease: tatD dehydratase: tyrosine superoxide α-Kdo-(2->6)- glutamyl-L-lysyl- glutathione dipeptidase a protein YddB kinase: thiM 5'-phosphate lyase acyl- 2-phospho-D-glycerate (G:U DNA crosslink phosphate 2-O- phosphate 2-O- phosphorylase: glucohydrolase: ribonucleoside- rph nudK phosphatidylethanolamine synthase: bioB glutamine NH - a 7,8-dihydrofolate kinase: coaE folate transformations III (E. coli) 5-semialdehyde 3-hydroxyacyl-CoA coenzyme A acetyl-CoA C- 3-hydroxyacyl-CoA fucO ligase: rtcB acyltransferase: quinone ADP-sugar acyl-CoA yjhG kinase: etk superoxide holo-[acyl 3 pyridoxine 5'- repair entF entE xapA RNase T IMP lipid IV (E. coli) D-alanyl-D-alanine Dcp substrate serine carrier protein] (S)-propane- specific): nth acyltransferase: acyltransferase: bglA diphosphate a [protein]- A YccF dependent: dependent: FMN molybdopterin N-acetylornithine dehydrogenase: acyltransferase: dehydrogenase: fadI reductase: nfsB pyrophosphatase: thioesterase: 2-dehydro- dismutase: carrier phosphate pyridoxamine citrate lyase ATP 1,2-diol glycosylase: plsC plsC exonuclease: rnt reductase: α L-tyrosine endoprotease: 4,5-secobiotin nadE dihydrofolate prenyl phosphate coenzyme A aminotransferase: enolase: eno fadJ fadI fadB nudF yciA -D-mannose 3-deoxy-D- sodC glutathione protein] nadE oxidase: 5'-phosphate a tetrahydrofolate pyruvate ycaQ a nucleoside 5'- a nucleoside peptidyl- degQ synthetase: biosynthesis α-D-ribose- nrdA nrdB RNA his208 PtsH 1-phosphate phosphate D-alanyl-D-alanine hydrolase: reductase: folM FMN gabT a 2,3,4-saturated 3-ketoacyl- a 2,3,4-saturated GMP a [DNA]-3'-α,β- uracil β-D-glucose a 2'- BglG-P GMP arabinonate superoxide YadC synthase: + pdxH oxidase: pdxH a 5'-phospho- enterobactin nicotinamide monophosphate diphosphate SafA dipeptidase: biotin NAD dihydrofolate flavin adenylyltransferase: citC 3-oxo-(9Z)-octadecenoyl-CoA RNA acetyl-CoA (7Z)-tetradecenoyl-CoA 1-palmitoyl-2- menadiol NAD + 1-palmitoyl- α 1-phosphate MeOH deoxyribonucleoside carboxypeptidase: ggt serine acpT acyl carrier protein N-acetylornithine fatty acyl CoA CoA 3-oxoacyl-CoA [DNA] unsaturated an -D-aldose 6-phosphate dismutase: synthase: bioB ribF cobalamin-dependent an acetyl-holo phosphoenolpyruvate ADP a DNA containing a mechlorethamine palmitoleoyl- 2-myristoyl AMP dacD dcp endoprotease: NlpD YagG phosphodiesterase: reductase: folA prenyltransferase: dihydrofolate aminotransferase: thiolase: aldehyde 1-phosphate 5'-diphosphate a carboxylate sodB holo-[acyl- methionine synthase: metH [citrate lyase acyl- ATP 3-ketoacyl-CoA AP sites on derived bis- sn-glycerol phosphatidate D-alanyl-D-alanine degS acpH lipoate ubiX PLP reductase: folM argD fadA biotin carrier- a tetrahydrofolate FAD folate polyglutamylation carrier protein] phosphoenolpyruvate pyruvate kinase: pykF synthase: thiolase: fadA opposing strands guanyl compound 3-phosphate superoxide a 1,2-diacyl- 7-O-[2- carboxypeptidase: L-cysteinylglycine biosynthesis and dihydrofolate reductase: folA glu a peptide protein] prenylated FMNH hydrogencarbonate synthetase: ppsA pyruvate kinase: pykA atpB atpF acetyl-CoA C- dismutase: sn-glycerol aminoethoxy(hydroxy) a dipeptide YraK 2 bis(guanylyl molybdenum EntF dacA a peptide biotin BioP biotin incorporation II 10 N-acetyl-L-ornithine acyltransferase: sodA phosphoryl]-α-D- synthase: 5,6,7,8- an N - 5,10-methylenetetrahydrofolate:glycine gcv system: lpd atpE atpD ω hydrogen glutathione-glutaredoxin cofactor) biosynthesis a 7,8-dihydrofolate a 5-methyltetrahydrofolate carbamoyl pyruvate UDP-N-acetylmuramoyl- 1-palmitoyl- 2,3- an N -(1- octanoate tetrahydrofolate formyltetrahydrofolate fadI hydrogen 37 phosphoenol a 5'-NAD- 6+ a mismatched Kdo-(2->4)-α-D- acpS hydroxymethyltransferase: glyA gcvP gcvH gcvT atpG atpA a [disordered-form [Fe-S] an S-sulfanyl-[L- arbutin 6-phosphate 6-decylubiquinol an adenosine a cis- 4-hydroxy- glu-Me Cr peroxide γ redox reactions MoO - acetylornithine a 5'-hydroxy- L-alanyl-γ-D- DMAPP sn-glycerol a purine dihydroxybenzoyl- PtsP PII-2 Tsr hydroxy-2- his717 RssB his NtrC L-alanyl- -D- octanoate- lipoate salvage I 2 phosphate acetyl-CoA an [RNA]-3'- GTP peroxide pyruvate capped-[RNA] ArcB-P NtrB-P DNA base pair XTP Kdo-(2->6)-lipid IV RzoD 10-formyl- atpH atpC ribonucleotide- cluster scaffold protein] cysteine desulfurase] in tRNA vaccenoyl-[acp] ribonucleoside UTP L-threonine A glutamyl-L- RlpA NAD salvage pathway II (PNC IV cycle) molybdopterin molybdopterin a (6S)-5-formyltetrahydrofolate deacetylase: synthetase: pyruvate (7Z)-hexadecenoyl-CoA ribonucleoside- glutamyl-meso-2,6- 3-phosphate EntB oxopropyl) methyl- D-ala non- tetrahydrofolylpolyglutamate thioredoxin ATP lysyl-D-alanine FimI an apo acyl- glutathione glutathione biosynthesis cofactor argE carB carA dehydrogenase: 3'-phosphate 3'-[RNA] diaminopimeloyl- -[protein]- directed lipoylated (R)-lipoate pathway acyl-CoA arbutin-6-phosphate quinol:hydrogen RNA chromate YghD synthetase: folC 5,10- 5-formyltetrahydrofolate aceE aceF lpd Carboxylate Degradation D-alanine tRNA L-arginine mismatch XTPase: carrier protein apo domain NAD + 5,10- scaffold acyl-[acp]:1-acyl- proofreading [protein PII-2] 4-hydroxy- protein-glutamate reductase: lipoate-ATP 10 bis(molybdenum NAD salvage L-ornithine dehydrogenase: 3'-PO4/5'- glucohydrolase: ascB peroxide decapping yjjX a tetrahydrofolate methylenetetrahydropteroyl an N - methylenetetrahydrofolate methylenetetrahydrofolatecyclo-ligase: fau carbamoyl phosphate protein for iron- dimethylallyltransferase: purine nucleoside thioesterase: uridylyltransferase: L-threonine methylesterase: repair: UDP-N-acetyl-α-D-muramoyl-L- ligase: lplA + an oxidized thymidylate synthase: thyA acetyl-CoA sn-glycerol-3- hydrolase: yieF a 2,3,4-saturated a [lipoyl-carrier NAD synthetase, glu adenylate formyltetrahydrofolate cofactor) pathway IV (from reductase: metF fadE OH RNA arbutin 6-phosphate oxidoreductase: miaA phosphorylase: mutL thiosulfate H O 4-nitrophenyl a β-lactam YabI 6 mono-L-glutamate dehydrogenase: folD superpathway of hexuronide sulfur cluster L,D- entH glnD aldolase: cheB protein alanyl-γ-D-glutamyl-meso-2,6- fatty acyl CoA 2 a glutaredoxin dithiol protein] N - transferase: thioredoxin synthase: mobA nicotinamide riboside) oxaloacetate ligase: rtcB glucohydrolase: bglA cydA cydB phosphate 2-O- nudC dGMP phosphate SfmD glutamine a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate and hexuronate degradation L-ascorbate ketogluconate metabolism 2-methylcitrate cycle I L-ascorbate degradation D-galactonate degradation assembly: iscU deoD ltaE mutS mutH XDP β-lactamase: YebF octanoyl-L-lysine lplA α 1-(β-D (2E,7Z)-hexadecenoyl-CoA cydX cydH carboxypeptidase: acyltransferase: deglycase: a properly diaminopimeloyl-D-alanyl-D-alanine nitrophenyl dependent: nadE folylpoly- - 5,10-methylenetetrahydrofolate:glycine ornithine degradation II arbutin 6-phosphate 6 dGMP phosphatase: phoA glutamate--cysteine [(R)- I (bacterial, anaerobic) 3+ RzoQ dacD glutaredoxin: grxC lipoyl ribofuranosyl) a β-D- ldcA N -(3-methylbut- plsC 2,3- hchA Cr superoxide matched thiosulfate- phosphatase: NAD phosphorylation + glutamate hydroxymethyltransferase: glyA bis(molybdenum methenyltetrahydrofolate carbamoyltransferase: malate citrate synthase: gltA (bacterial, aerobic) glucohydrolase: bglB PtsP- pyruvate acyl-CoA protein-disulfide NAD synthetase, ligase: gshA lipoyl]adenylate enoyl-CoA 2,5-didehydro- propanoate D-galactonate 2-en-1-yl)- α-D-ribose- uridylyl- a 5'-phospho- MeOH glu deoxyribonucleoside penicillinase: synthase: thioredoxin nicotinamide guanylyl molybdenum glucuronoside GMP an S-sulfanyl-[cysteine dihydroxybenzoate b0595 NMN Tsr ArcB NtrB asp DNA base pair sulfurtransferase: ygaP muramoyl pentapeptide ushA synthetase cofactor) ribosylnicotinamide cyclohydrolase: folD argF dehydrogenase: mdh L-ascorbate superpathway of D-glucarate 37 phosphorylated RssB-P NtrC-P thioesterase: and dephosphorylation reductase NH -dependent: nadE γ lipoyl- malate:quinone hydratase: fadJ L-ascorbate D-gluconate RNA adenosine 1-phosphate [protein PII-2] adenosine-[RNA] glycolaldehyde 5'-monophosphate dacA DinQ lipA 3 gly -L-glutamyl- a 5,10- S-adenosyl- cytidylyl molybdenum reductase: kinase: nadR cofactor biosynthesis β-D- desulfurase]-[disordered-form 6-decylubiquinone H O UDP-N-acetyl-α-D- 1-palmitoyl-2- a purine base gly thiosulfate carboxypeptidase: dacC nicotinate adenine dinucleotide NMN folylpoly-γ- bis(molybdenum ornithine oxidoreductase: mqo malate dehydrogenase enoyl-CoA propionyl- transport and and D-galactarate degradation D-galactonate 2 a [protein]- phosphatase: yfbR tesA 4-nitrophenyl (glutathione): grxA a [lipoyl-carrier L-cysteine adenylate- cofactor biosynthesis trxB 10 in tRNA (R)-lactate β-lactamase: RhsD NAD + methylenetetrahydrofolate L-methionine NMN MoO - an N -formyltetrahydrofolate acetyl-CoA glucuronidase: scaffold protein] complex β-D-glucose 6-phosphate hydroquinone D-ala muramoyl-L-alanyl- cis-vaccenoyl L-arginine sulfurtransferase: pspE muramoylpentapeptide phosphate 6 glutamate cofactor) 2 carbamoyltransferase: (oxaloacetate- hydratase: fadB 2,5-diketo- CoA phosphorylation dehydratase: 5'-deoxyribonucleotidase: EcnB glutathione:protein protein]-N -[(R) -protein biosynthesis MoO - molybdopterin uidA γ-D-glutamyl-meso- phosphatidate ampC 2 galactarate D-glucarate dgoD YccM thiosulfate carboxypeptidase: dacA phosphatase: -dihydrolipoyl]- ligase: lplA synthetase: methylene- synthase: mobA NMN argI decarboxylating): maeA (S)-3-hydroxy-(7Z) D-gluconate synthetase: of L-ascorbate: ushA a 2,3,4-saturated a substituted disulfide NMN glutathione molybdopterin cofactor molybdenum cofactor malate synthase A: aceB dehydroascorbate 2,6-diaminopimelate sulfurtransferase: glpE phoA a [lipoyl-carrier folC tetrahydrofolylpolyglutamate bis(guanylyl reductase: 2-keto-D- prpE ulaC ulaB ulaA 2-dehydro-3-deoxy- fatty acid β-amino acid YpfN reductase: grxB L-lysine synthetase: met cofactor molybdenum cofactor a reduced adenylyltransferase: guanylyltransferase: (S)-malate citrate -hexadecenoyl-CoA D-glucopyranuronate L-ascorbate 2'-deoxyribonucleoside amidohydrolase: 6 synthetase: folC molybdopterin) UDP-N-acetylmuramoyl-L- 4-nitrophenol pyridine nucleotide NAD nicotinate-nucleotide protein]-N -[(R methionine nadR dkgA gluconate propanoate:CoA 6-phosphate galactarate D-glucarate D-galactonate 5'-monophosphate NADP pncC gshB cytidylyltransferase: thioredoxin cofactor guanylyl mobA L-citrulline 3-hydroxyacyl-CoA GMP-N-ε-(N-α-acetyl iron(III)-[N-(2,3- a 5'-phospho- alanyl-γ-D-glutamyl-meso-2,6- YraH transhydrogenase: kinase: a protein with reduced adenylyltransferase: )-lipoyl]-L-lysine a 5,10- asp ligase (AMP- a pyrimidine base a 2,3,4-saturated 1-palmitoyl- (2R,3S)-3- (2E,5Z)- thiocyanate sulfite D-ala a tetrahydrofolate adenosyltransferase: cytidylyl molybdenum dehydrogenase: 2,5-diketo- dehydratase: dehydratase: 2-dehydro-3- a 2,3,4-saturated an aminopeptidase a uridylylated 34 phosphatase: aphA phosphatase mocA + L-ascorbate- a 2,3,4-saturated 2- an mRNA lysine methyl ester) dihydroxybenzoyl)-L- ribonucleoside- glu-Me a cytidine GDP diaminopimeloyl-D-alanine pntB pntA nadK L-cysteine residues nadD methylenetetrahydrofolate NAD forming): acs lesion in DNA 2-oxoglutarate gln NADPH H + 1,2-diacyl-sn- sn-glycerol a palmitoyl-[acp] PII-1 isopropylmalate ATP Tar BglF-P cys24 BglG FruB-P his299 BglG lys dodecenoyl-CoA metK molybdenum fumarase: fumE citrate hydro-lyase: acnB D-gluconate garD gudD deoxygalactonokinase: fatty acyl-[acp] substrate PII protein Ile2 ITP YncL glutathione cofactor fadJ 2,3-didehydro- 6-phosphate lysophosphatidate CTP 5'-phosphoramidate 3-phosphate serine trimer] complex UTP 3-isopropylmalate [RNA] in tRNA enoyl-CoA nucleoside 2'-deoxyguanosine Slp NaMN SAM reductase: glycerol 3-phosphate IbsE cofactor (dioxo) argininosuccinate fumarase: fumD citrate hydro-lyase (cis- 3-hydroxyacyl-CoA aldehydo-D- aldehydo-D- fatty lactonase: dgoK L-gulonate 2-dehydro-3-deoxy- dehydrogenase hydratase: di- and synthetase: argG fumarase A: fumA aconitate-forming): acnA galacturonate glucuronate dkgB acyl-CoA ulaG bifunctional ribosome- dehydrogenase: (decarboxylating) Ile fadJ triphosphate ITPase: + 2,3-diketo- 2,5-diketo- D-galactonate L-glutamate:NADP+ acyl-[acp]:1-acyl- CTP:2,3,4-saturated purine nucleoside acyl-[acp]:1-acyl- aminopeptidase: ferric-chelate [protein-PII-UMP] [protein PII-1] RNA 5' protein-glutamate tRNA - YnfD NADP fumarase B: fumB fadB D-glucuronate synthetase: 3-dehydro- DNA dependent yjjX D-galacturonate L-gulonate D-gluconate 6-phosphate oxidoreductase sn-glycerol-3- L-phosphatidate phosphoramidase: sn-glycerol-3- mtfA reductase: deuridylylation: uridylyltransferase: : dmlA adenylyl methylesterase: lysidine enoyl-CoA hydrolase: L-alanyl-γ-D- a peptidoglycan internal segment peptidoglycan fumarase C: fumC isomerase: 2-keto-L-gulonate fadD L-gulonate glycosylase: mRNA 3'-UMP L-arginino-succinate fumarate cis-aconitate 3-oxo-(7Z)- isomerase: uxaC reductase: reductase: 2-keto-D- 5-dehydro-4- (transaminating) phosphate 2-O- cytidylyltransferase: hinT phosphate 2-O- nfeF glnD glnD 3-isopropylmalate transferase: cheB synthetase: hydratase: nudJ EutH glutamyl-meso-2,6- with (L-alanyl-γ-D-glutamyl- DAP-DAP protoheme D-cysteine DsbA 6-phosphate nei interferase: aminopeptidase: oxidized PpdC hexadecenoyl-CoA uxaC yiaK gluconate short chain 2-dehydro-3-deoxy-6- dehydrogenase: tilS fadB IDP diaminopimeloyl- meso-2,6-diaminopimeloyl- crosslink 3'UMP GfcE Aminoacyl-tRNA Charging D-threo-isocitrate D-tagaturonate ghrB 2-keto-L- 3-keto-L- deoxy-D-glucarate : gltB gltD acyltransferase: cdsA yoeB acyltransferase: ypdF rtcA argininosuccinate glyoxylate 3-ketoacyl-CoA reductase: acyl-CoA leuB (S)-3-hydroxy-(5Z) GMP succinate:quinone hydro-lyase: acnB D-fructuronate 3-dehydro- gulonate-6- phosphogalactonate plsC plsC N-(2,3- UMP D-alanine D-glycine) tetrapeptide phosphatase: lyase: argH gulonate ghrB synthetase: a [DNA]- N-α-acetyl lysine 2+ uridylyl- 4-methyl-2- -dodecenoyl-CoA YadM thiolase: fadA tagaturonate L-gulonate α-dehydro- aldolase: dgoA a 5'-phospho- a modified dihydroxybenzoyl) Fe MeOH glu deferrochelatase: phoA tRNA charging oxidoreductase: sdhD D-threo-isocitrate reductase: phosphate nucleotide- 4-oxo-2-pentenal a CDP-2,3,4-saturated- a PII protein a 5'-(5'- Tar BglF his101 his208 FruB a lysidine 34 peptidoglycan LD- D-mannonate fadK β [DNA] nucleobase an RNase an RNase product methyl ester GMP [protein PII-1] oxopentanoate BglG-P BglG-P acetyl-CoA C- reductase: -deoxy-D a proteinogenic -L-serine trimer diphosphoadenosine)- Ile2 peptidoglycan LD- efeB sdhC sdhB sdhA hydro-lyase (cis- 3-keto-L- ghrB decarboxylase: 3'-phosphate glu + diacylglycerol product with dipalmitoyl a peptide in tRNA YjeT glycine endopeptidase: uridine 3'- YbbW arg oxidoreductase: D-glyceraldehyde NADP a 2,3,4-saturated 1,2-diacyl- with a 5' OH amino acid carboxypeptidase: aconitate-forming): acnA acyltransferase: uxaB gulonate propanoyl-CoA ulaD -glucarate pyruvate (ribonucleoside)-[RNA] carboxypeptidase: mepA nucleotidase: uxuB 3-phosphate sn-glycerol 3-phosphate a 3' phosphate phosphatidate Ala Arg Asn asp Cys Gln glu Gly His Ile Leu Lys Met Met Phe Pro ser Thr Trp Tyr fadI kinase: L-idonate aldolase: garL mepS cpdB a tRNA ala arg a tRNA asn tRNA tRNA asp cys a tRNA gln a tRNA glu a tRNA gly a tRNA his a tRNA ile a tRNA leu a tRNA lys a tRNA elongator tRNA met initiator tRNA met phe a tRNA pro a tRNA ser a tRNA thr a tRNA trp a tRNA tyr a tRNA isocitrate lyase: aceA D-altronate L-xylulose dpaA peptidogylcan LD- OmpL val a tRNA Val arginine 2+ PpdD succinate D-threo-isocitrate D-mannonate lyxK 2-methylcitrate 5-phosphate γ Fe protoporphyrin IX uridine decarboxylase: (5Z)-tetradecenoyl-CoA L-idonate 5- L-alanyl- -D- endopeptidase: isocitrate 3-dehydro- synthase: prpC pyruvate tartronate semialdehyde di-trans,octa-cis a single stranded an S-(1-hydroxy- a peptidoglycan internal segment D-cystine DsbA PdeN speA dehydrogenase: L-ribulose-5- α 3-oxo-(11Z)- salicin 6- lysine within thiamine a [protein]- SulA D-ala glutamyl-meso- mepK alanine--tRNA arginine--tRNA asparagine--tRNA aspartate--tRNA cysteine--tRNA glutamine--tRNA glutamate--tRNA glycine--tRNA histidine--tRNA isoleucine--tRNA leucine--tRNA lysine--tRNA ligase: lysS methionine--tRNA methionine--tRNA phenylalanine--tRNA proline--tRNA L-serine:tRNASer ligase threonine--tRNA tryptophan--tRNA tyrosine--tRNA L-ornithine D-altronate L-gulonate Reactive blue 5 1-cis-vaccenoyl-sn- β-D-fructofuranose 1-phosphate UDP- -D-glucose pyruvate a carboxylic ester (R)-lipoate Npr glu-Me D-gluconate cyanate ATP RNA dehydrogenase: icd acyl-CoA (2S,3S)-2- a palmitoleoyl-[acp] -undecaprenyl DNA with ring- an N-terminal phosphate a protein PtsN Tap 2-oxopropyl) ADP L-histidine diaminopimelate with (L-alanyl-γ-D-glutamyl-meso gly ligase: metG ligase: proS valine--tRNA ligase: valS succinyl-CoA dehydratase: D-mannonate idnD phosphate 3- inosine octadecenoyl-CoA ATP gcv protein H diphosphate ligase: alaS ligase: argS ligase: asnS ligase: aspS ligase: cysS ligase: glnS ligase: gltX ligase: glyS glyQ ligase: hisS ligase: ileS ligase: leuS lysine--tRNA ligase: lysU ligase: metG ligase: pheS pheT (AMP-forming): serS ligase: thrS ligase: trpS ligase: tyrS dehydrogenase: 6-phosphate tartronate citrate degradation glycerol-3-phosphate fructose-1- phosphate opened apurinic/ L-cysteinyl- phosphorylated -[protein]- D-gluconate 5- protein- -2,6-diaminopimelate) tripeptide agmatine synthetase: sucD sucC dehydratase: methylcitrate epimerase: peptidoglycan peptidoglycan a polymyxin ABC-type a polymyxin SAM fadE uxaA 3-keto-L- 5-dehydro- semialdehyde apyrimidinic site [YedK-protein] L-cysteine dehydrogenase: histidine YmdA lys uxuA 2-methylcitrate ulaE phosphatase: yqaB tetrapeptide, tripeptide, ornithine gulonate-6- D-gluconate reductase: garR an acetyl-holo dye- pyruvate- 3-ketoacyl-CoA salicin 6- carboxylesterase: lipoate-apo- kduD poly(A) bacitracin tripartite bacitracin Ala Arg Asn asp Cys Gln Glu Gly His Ile Leu Lys Met Met Phe Pro ser Thr Trp Tyr Val dehydratase: acyl-[acp]:1-acyl- sugar phosphatase: ybiV bactoprenyl protein protein-glutamate ThDP cyanase: pros- glycan chain 2 glycan chain 1 YhfL an L-alanyl-[tRNA ] an L-arginyl-[tRNA ] an L-asparaginyl-[tRNA ] an L-aspartyl-[tRNA ] an L-cysteinyl-[tRNA ] an L-glutaminyl-[tRNA ] an L-glutamyl-[tRNA ] a glycyl-[tRNA ] an L-histidyl-[tRNA ] an L-isoleucyl-[tRNA ] an L-leucyl-[tRNA ] an L-lysyl-[tRNA ] an L-methionyl-[elongator tRNA ] an L-methionyl-[initiator tRNA ] an L-phenylalanyl-[tRNA ] an L-prolyl-[tRNA ] an L-seryl-[tRNA ] an L-threonyl-[tRNA ] an L-tryptophanyl-[tRNA ] an L-tyrosyl-[tRNA ] an L-valyl-[tRNA ] agmatinase: decarboxylase: (2E,5Z)-tetradecenoyl-CoA L-ribulose 5- [citrate lyase acyl- decolorizing flavodoxin thiolase: fadA phosphate yjfP GcvH protein polymerase: a macrolide antibiotic efflux pump a macrolide antibiotic phosphate citrate sugar phosphatase: hxpA inosine methylesterase: 5-keto-D- adenylyl cynS kinase: CvpA speB speC S-adenosylmethionine lysine prpD phosphate D-glycerate carrier protein] peroxidase: sn-glycerol-3- glucosyl genome oxidoreductase: glucohydrolase: adenylyltransferase: ligase: lplA protein pcnB decarboxylase: 5-keto-D- nucleosidase: acetyl-CoA C- carboxylesterase: cheB gluconate 5- transferase cusS decarboxylase: speD decarboxylase: succinyl-CoA 2-oxoglutarate cis-2- L-ribulose-5- yfeX phosphate 2-O- sugar phosphatase: yidA transferase: maintenance ydbK bglB selO deglycase: a [protein]- L-alanyl-γ-D- 2-deoxy-D- 3 2 sgbH acyltransferase: bioH a protein with a [disulfide- ∆ ∆ gluconate 5- rihC π ldcC -cis- -trans- enoyl-CoA methylaconitate glycerate 2- citrate-ACP acyltransferase: plsC phosphosugar yfdH protein: yedK hchA reductase: N -phospho- a [protein]-L-proline (ω = 180) YfcV 2-dehydro- reductase: phosphate 4- fadI a [glycine-cleavage glutamyl-meso-2,6- reduced L- bond carrier 2'-deoxyadenosine cys DsbA glucose 6- putrescine dAdoMet enoyl-CoA hydratase: fadJ L-xylulose kinase: glxK idnO adenosine ammonium CO oxidized multidrug lysine (2R,3S)-2- epimerase: transferase: phosphatase: yigL 6 2 RNA L-histidine diaminopimeloyl- peptidyl-prolyl cis- phosphate YedD 3-deoxy-D- 5-phosphate idnO 3-[(4-amino-6-chloro- β-D-glucose an adenylated complex H protein] N PtsN- cysteine residues protein] carrying 3'-monophosphate YfaL isomerase: fadB enoyl-CoA glycerate 2- 2,2'-disulfonyl a single stranded a reduced Npr MeOH glu 5-dehydro- thiamine 2-deoxy-D- a gentamicin efflux pump a gentamicin Nucleoside and Nucleotide Biosynthesis decarboxylase: methylisocitrate ulaF citD citF citE 1,3,5-triazin-2-yl) phthalate phosphosugar UDP acetyl-CoA CO D-ribofuranose salicyl alcohol an alcohol a carboxylate -[(R)-lipoyl]-L-lysine Tap a [protein]- RsxE D-alanine a disulfide bond trans isomerase: surA Carbohydrate Biosynthesis gluconate L-xylulose 5- azobenzene 1-cis-vaccenoyl-2-palmitoleoyl- β-D-Glc-PP-Und 2 6-phosphate protein phosphorylated (R)-lactate D-gluconate triphosphate glucose 6- cadA hydratase: fadB hydro-lyase: acnB kinase: garK phosphatase: phoA DNA-YedK flavodoxin hypoxanthine peptidyl-prolyl cis- 2'-deoxyadenosine AcrAD-TolC 2-oxoglutarate 2-dehydro-3- D-xylulose amino]benzenesulfonate sn-glycerol-3-phosphate acetyl-CoA palmitoleoyl-CoA L-cysteine phosphate spermidine (3E,5Z)-tetradeca- phosphate 3- a citryl-holo β-D-fructofuranose thiazolidine linkage peptidoglycan LD- protein disulfide 3'-monophosphate YcbU superpathway of purine nucleotides de novo biosynthesis II dehydrogenase: deoxygluconokinase: (2R,3S)-2- 5-phosphate 2-phospho-D-glycerate trans isomerase: fkpA superpathway of pyrimidine superpathway of pyrimidine adenine and adenosine salvage III superpathway of pyrimidine ribonucleosides salvage colanic acid (Escherichia coli K-12) biosynthesis synthase: cadaverine 3,5-dienoyl-CoA (S)-3-hydroxy-(5Z) epimerase: [citrate lyase acyl- carboxypeptidase: oxidoreductase: phosphatase: aphA phosphatase: YbfP pyrimidine superpathway of enterobacterial common antigen biosynthesis glycogen biosynthesis I (from ADP-D-Glucose) sucA sucB lpd kdgK methylisocitrate peptidyl-prolyl cis- curli deoxyribonucleotides de novo biosynthesis ribonucleotides de novo biosynthesis speE acyl-CoA -tetradecenoyl-CoA sgbU carrier protein] mepS dnaJ phoA ribonucleosides trans isomerase: fklB 2'-deoxyadenosine 2-deoxy- secretion PRPP cytidine α aminopropylcadaverine thioesterase: L-ribulose 5- citryl-ACP a [50S ribosomal a [ThiI sulfur- YeeR HofQ salvage III UDP- -D-glucose D-glucopyranose 3-hydroxyacyl-CoA KDGP 2-methylisocitrate a pyrimidine base (1S,2R)-1- a nucleoside a trans-2- a [protein]- D-glucose CsgA and CsgA α-D-glucopyranose 1-phosphate synthase: speE D-gluconate 2-oxoglutarate an exoaminopeptidase a peptide with a 5'-deoxyadenosine phenylacetyl-CoA H O PtsP- glu-Me AMP glyoxylate L-alanyl-γ-D- a [disulfide-bond peptidyl-prolyl cis- fadM phosphate lyase: citD PflB SAM subunit protein cys carrier protein]- 2 acetyl phosphate Trg RNA gln hydrogencarbonate gln adenine cytidine 6-phosphate dehydrogenase: lyase: prpB lesion in DNA ser C-(indol-3- IMP RssB ITP Npr triphosphate GTP SucB lipoyl-ACP enoyl-[acyl- L-histidine a protein with L-cystine DsbA assembly hydrogencarbonate cytidine cytidine UDP- citF citE 81 substrate leader sequence phosphorylated glutamyl-meso- carrier protein] trans isomerase: slyD YacH amidophosphoribosyltransferase: purF adenosine cytidine fadB L-ribulose-5- D- pyruvate decarboxylation to acetyl CoA I L16]-L-arginine L-cysteine yl)glycerol carrier protein]enoyl-[acyl- glyoxylate protein- D-ala a disulfide bond YkgR glucose-1-phosphate spermidine aminopropylcadaverine (3E,5Z)-tetradecadienoate propanoyl CoA diaminopimelate with reduced L- peptidyl-prolyl cis- complex phosphorylase: ppnP deaminase: cdd kinase: udk nucleosidase: rihC glucose:undecaprenyl- phosphoglucomutase: Macromolecule Modification 2-keto-3- phosphate 4- gluconate 3-phosphate inosine triphosphate reductase: histidine thymidylyltransferase: rffH 3-hydroxyacyl-CoA degradation I oxaloacetate bifunctional phenylacetyl- carrier- trans isomerase: ppiA 5-phospho-β- carbamoyl phosphate glucose- pgm deoxygluconate epimerase: superpathway of acetate pyruvate succinate a [pyruvate pyruvate formate- protein- 5'-deoxyadenosine pyrophosphatase: rdgB RNA ghrB tele- cysteine residues ferrichrome carbamoyl adenosine cytidine dehydrogenase: kinase: idnK DNA cysteine leader protein-glutamate AMP protein] YnfS uridine CMP 1-phosphate glucose-1-phosphate α-D- utilization and formation dehydrogenase arginine metalloaminopeptidase: tryptophan nucleosidase: mtn CoA nucleoside triphosphate lipoyl-protein kinase: a [protein]-L-proline (ω = 0) D-ribosylamine phosphate phosphate phosphorylase: deoD nucleosidase: rihB tRNA-uridine 2-thiolation and selenation (bacteria) fadJ 6-phosphate sgbE D-gluconate lyase activating desulfurase inosinate peptidase: methylesterase: polymerase: reductase: glyoxylate outer AppX 6 37 6 pyruvate propanoyl-CoA glycosylase: ypdE thioesterase: kinase ligase: lipB synthetase: adenosine transferase: wcaJ thymidylyltransferase: glucopyranose N -L-threonylcarbamoyladenosine aldolase: eda E2 protein] N enzyme: pflA oxygenase: synthase: nucleosidase: pyrophosphohydrolase: cheB rpoA reductase: cpxA ferrichrome membrane ferrichrome YddK phosphoribosylamine--glycine synthetase: cytidine 3-oxo-(5Z)- D-xylulose 6-phosphate propionyl- nth IscS: iscS lepB paaI (GTP): adk fabI a [protein]- YjeM carB carA uridine CMP kinase: cmk rfbA UDP-N-acetyl-α-D-glucosamine 1-phosphate -modified tRNA biosynthesis acetate -lipoyl-L-lysine roxA trpA trpB ppnN mazG rpoC rpoB ligase: purD carB carA α β 5-phosphate acetyl-CoA pyruvate:[dihydrolipoyllysine- CoA an acyl-[acyl- ghrA τ transport nucleosidase: rihA -D-Glc-PP-Und GDP- -L-fucose cys tetradecenoyl-CoA N -phospho- uridine nucleosidase: rihB cytosine α UDP-N- glucose-1-phosphate D-glyceraldehyde synthetase lipoate residue acetyltransferase]- 5-deoxy-D-ribose IMP carrier protein] a peptidoglycan internal segment an L-1- an E. coli osmoregulated complex CDP dTDP- -D-glucose acetyl-CoA C- pyruvate carboxylase α β a [ThiI sulfur- D-glyceraldehyde acetate glycolate L-histidine adenosine deaminase: add kinase: udk uridine adenylyltransferase: thr 3-phosphate acetate (AMP- acetyltransferase (S)-methylmalonyl- activated pyruvate- a 5'-phospho- a [DNA]-3'- , - a modified a [50S ribosomal a proteinogenic adenine Npr ADP GDP MgtS with (L-alanyl-γ-D-glutamyl-meso-2,6- a murein lipoprotein periplasmic glucan (OPG) 2'-deoxyguanosine a protein 2'-AMP GAR carbamoyl acetylglucosamine lipoyllysine 2- 5'-deoxyadenosine met a peptide ala carrier protein]- D-ribofuranose a leader sequence a peptide RssB-P PtsP MeOH Trg glu SucB-lipoate phosphatidylethanolamine dAMP hydrophilic hydrophilic carbamoyl phosphate asp cytosine α acyltransferase: 6 unsaturated succinate 3-phosphate trp phenylacetate asp nucleosidase: rihA GDP-Fuc: -D-Glc- dTDP-glucose 4,6- glgC L-cysteine:[protein kinase: forming): acs N -(dihydrolipoyl) oxidoreductase: aceE CoA formate lyase [DNA] nucleobase subunit protein L16]- amino acid phosphorylated RNA diaminopimeloyl-D-alanine) tetrapeptide 3'-monophosphate β-barrel assembly- phosphate deaminase: codA di-trans,octa-cis- 2-epimerase: wecB L-threonylcarbamoyladenylate fadI conversion of succinate to propanoate S-sulfanyl- 5-phosphate hypoxanthine dAMP phosphatase: phoA 2'AMP solute < OmpG solute < RssA PspG PP-Und α-(1,3)- dehydratase: rffG a (1->4)- cysteine] ackA lysine:NAD+ aldehyde (3R)-3-hydroxy- Ag43 phosphoribosylglycinamide uracil uridine undecaprenyl phosphate α α synthase: tsaC methylmalonyl- L-cysteine enhancing phosphatase: 900 Da 900 Da UDP-N-acetyl- -D-glucosamine UDP-N-acetyl-α-D-mannosamine ADP- -D-glucose 81 dAMP 2'-deoxyguanosine formyltransferase 2: purT UMP uracil fucosyltransferase: dTDP-glucose 4,6- α-D-glucan Metabolic Regulator Biosynthesis sulfurtransferase: iscS (L-threonylcarbamoyl) 3-ketoacyl-CoA oxidoreductase: lpd L-arginine protease: bepA aspartate inosine phosphoribosyltransferase: upp nucleosidase: rihC a [pyruvate a [pyruvate CoA epimerase L,D-transpeptidase: ldtB 3'-monophosphate phoA aspartate CDP kinase: adk wcaI dehydratase: rfbB glycogen L-cysteine adenylate thiolase: fadA acetyl phosphate acetyl-CoA succinyl-CoA phosphohydrolase: yfbR carbamoyltransferase: UDP-N-acetylglucosamine--undecaprenyl- UDP-N-acetyl-D- D-malate dehydrogenase dehydrogenase L,D-transpeptidase: ldtC periplasmic serine carbamoyltransferase: UMP kinase: pyrH 6 D-gluconate methylmalonyl- (R)-methylmalonyl- YhhM 5'-deoxyribonucleotidase: phosphatase: aphA FGAR uracil CDP kinase: ndk dTDP-4-dehydro-6- synthase: desulfurase: sufS N -L- degradation 6 E2 protein] N 6 -S- hexane hexane pyrB pyrI inosine phosphorylase: ppnP α-L-Fuc-(1->3)- phosphate N- mannosamine ppGpp metabolism (3Z)-dodec-3-enoyl-CoA degradation propionyl- CoA E2 protein] N CoA 3-oxo-(7Z)- a precursor of dTMP CMP a peptide with phosphoenol 1-myristoyl- 5-dehydro- activated an L-1- L,D-transpeptidase: ldtA endoprotease adenosine multidrug YfaT pyrB pyrI deoxy-α-D-glucopyranose glgA trehalose biosynthesis I glycine betaine threonylcarbamoyladenine a supercoiled duplex DNA a D-aminoacyl- L-cysteine N-methyl-L- ushA 3,6-diamino-10-methylacridinium 3,6-diamino-10-methylacridinium Ag43 inosine phosphorylase: xapA α dehydrogenase: an [L-cysteine desulfurase]- -dihydrolipoyl- acetyldihydrolipoyl- TdcE SAM a single stranded DNA large subunit of cys lysine within a lipoyl-[acp] an N-terminal PtsH sn-glycerol AceF lipoyl-ACP 4-deoxy-D- pyruvate- phosphatidyl- an E. coli osmoregulated 2'-deoxyguanosine DegP: degP efflux pump phosphoribosylformylglycinamide UDP -D-Glc-PP-Und acetylglucosaminephosphotransferase: rfe biosynthesis I (Gram- CoA:succinate mutase: scpA lipoate methylmalonyl- dGTP tetradecenoyl-CoA [tRNA] desulfurase deoxyribonucleoside XTP tryptophan pyruvate an erythromycin an erythromycin inosine phosphorylase: deoD dTDP-4-dehydro- wecC a (1->4)- S-sulfanyl-L-cysteine synthase: tsaE tsaD tsaB dodecenoyl-CoA (R)-malate L-lysine L-lysine DNA 3'-5' helicase: uvrD gcv protein H 3-phosphate sn-glycerol a 1,2-diacyl-sn-glycerol 2'-deoxyribonucleoside 6 D-gluconate CoA hydrogenase 3 L-alanine acyl-CoA:1-acyl- glucuronate5-dehydro- formate lyase periplasmic glucan with a peptide AcrEF-TolC CsgE synthetase: purL α-L-fucosyl-(1->3)- α-D-glucan pppGpp D-glucopyranose negative bacteria) an N -L- acetyltransferase: CoA 5'-monophosphate pyrimidine- pyruvate lipid a peptidoglycan tripeptide 5'-monophosphate deoxycholate deoxycholate N-carbamoyl-L-aspartate N-carbamoyl- UDP kinase: adk pyrimidine deoxyribonucleotide 6-deoxy-D-glucose UDP-N-acetyl-α-D- UDP-α-D-glucose D-isomerase: fadJ D-malate D-gluconate phosphate Rep helicase: rep xanthosine triphosphate phosphotidylethanolamine β-D-glucopyranosyl- α-D-GlcNAc-PP-Und guanosine-5'- 6-phosphate IscS:TusA threonylcarbamoyladenine 37 L-galactonate transferase: aceF mutase: scpA sn-glycerol-3- 4-deoxy-D- formate- crosslinked to murein lipoprotein D-ala L-aspartate UDP kinase: ndk transaminase: wecE α ∆ 3 2 ssDNA-specific 3-ketoacyl-CoA phosphatase: yfbR pyrophosphatase: rdgB 5'-nucleotide kinase: phosphatase: aphA hypoxanthine phosphorylation mannosaminuronate 1,4- - guanosine 3'-diphosphate triphosphate,3'-diphosphate choline sulfurtransferase: tusA -cis-∆ -trans- dehydrogenase kinase: gntK acetyltransferase: scpC pyruvate formate- 3' to 5' ATP-dependent hydrogenase D-aminoacyl- cysteine alanyl phosphate 2-O- glucuronate HokE substituent FGAM diphosphoundecaprenol in tRNA degradation (R)-methylmalonyl- thiolase: fadA lipoyl-protein nucleosidase: N-methyl-L- lipoyl-protein lyase yegS YigG dTDP-4-amino-4,6- glucan choline enoyl-CoA (decarboxylating) D-gluconate eutD propanoyl-CoA succinyl-CoA exonuclease: recJ DNA helicase: recB 5'-deoxynucleotidase: nucleoside triphosphate 2'-deoxyadenosine SfmF dihydroorotase: UTP salvage pathways of pyrimidine O-acetyltransferase: wcaF 5'-triphosphate 3'- phosphatase: gpp trehalose-6- lyase activating dGTP 3 maturation tRNA desulfurase: tryptophan aminopeptidase: acyltransferase: isomerase: deactivase: 1-(3-sn- dihydroorotase: pyrC hypoxanthine dTMP dCMP dideoxy-α-D-galactose UDP-N-acetyl-D- branching GTP dehydrogenase: a [TusA sulfur-carrier protein]- : dmlA CoA exodeoxyribonuclease acetyl-CoA C- ligase: lipB yfdR pyrophosphohydrolase: ppnN ligase: lipB ethidium multidrug ethidium phosphoribosylformylglycinamide deoxyribonucleotides α diphosphatase: spoT isomerase: fadB kinase: idnK L-galactonate phosphate enzyme: pflA ATP-dependent 3' protease: hycI deacylase: iscS oxidase: solA pepN plsC kduI adhE phosphatidyl) pyrC dTMP dCMP 2/3-O-Ac- -L- phosphate S-sulfanyl-L-cysteine pyruvate D-gluconate VII: xseA xseB triphosphohydrolase: dgt acyltransferase: 2'-deoxyribonucleoside mazG 1-myristoyl-2- 3-deoxy-D- phosphoribosyltransferase: gpt dTDP-4-amino-4,6- mannosaminuronic enzyme: pyrophosphokinase: relA betA L-galactonate dtd an erythromycin efflux pump an erythromycin cyclo-ligase: purM CTP kinase: tmk kinase: cmk Fuc-(1->3)-α- synthase: otsA (2E)-dodec-2-enoyl-CoA 6-phosphate acetyltransferase: pta -> 5" helicase: recQ palmitoleoyl- glycero-2,5- PflB -sn-glycerol YhcD (S)-dihydroorotate hypoxanthine 2'-deoxycytidine GDP-β-L-fucose dideoxy-D-galactose acid transferase: rffM glgB betaine aldehyde TusA:TusD oxidoreductase: acetyl-CoA fadI a [glycine-cleavage 5'-monophosphate XMP D-ribofuranose cytosine deoxycholate MdtEF-TolC deoxycholate (S)-dihydroorotate synthetase: pyrG dTDP dCDP D-Glc-PP-Und activated 2-ketobutyrate DNA helicase: helD a C terminal an S-sulfanyl- sn-glycerol hexodiulosonate 3-phosphate YdiK lipid A-core a nascent peptidoglycan a 2'- D-myo-inositol YhjD sulfurtransferase: 6 phosphatase: aphA pyruvate a 1-palmitoyl-2-acyl- AIR phosphoribosyltransferase: hpt deoxycytidine acyltransferase: rffC α α lgoD 5'-deoxyadenosine a single-stranded a large subunit complex H protein] N 5-phosphate formaldehyde his15 AceF-lipoate 3'-cmp YgiL β-D-ManNAcA-(1->4) a glycogen GTP ppGpp , -trehalose betaine aldehyde enoyl-CoA formate-lyase / pyruvate a ribonucleoside a single stranded DNA 32 amino- ala [L-cysteine trp ala a peptide HPr-P 3-phosphate oligosaccharide (E. (meso-DAP containing) deoxyribonucleoside (1,2,3,4,5)- 3'-GMP dihydroorotate deaminase: cdd dTDP dCDP gluconeogenesis I tusB tusC tusD D-tagaturonate methylmalonyl- triphosphate of hydrogenase 3 an uncharged -[(R)-lipoyl]-L-lysine thymidine phosphatidylethanolamine dihydroorotate GDP-Fuc:2/3-O-Ac- dTDP-4-acetamido-α-D-fucose α 6-phosphate dehydrogenase: hydratase: fadJ formate-lyase 4 5'-monophosphate oligodeoxyribonucleotide 2'-deoxyguanosine acid peptide a D-amino acid desulfurase] coli K-12 core type) 5'-monophosphate pentakisphosphate 3'CMP 5-(carboxyamino) dehydrogenase: pyrD IMP kinase: adk kinase: adk - -D-GlcNAc-PP-Und a [TusD sulfur-carrier protein]- CoA acetyl-CoA (5Z)-dodecenoyl-CoA tRNA 2'-deoxyribonucleoside D-myo-inositol guanosine 3'- dehydrogenase: CTP 2'-deoxyuridine α-L-Fuc-(1->3)-α-D- betB enoyl-CoA phosphatase: phoA hydrophilic hydrophilic imidazole PRPP dTDP dCDP trehalose-6- S-sulfanyl-L-cysteine decarboxylase: endolytic murein 5'-monophosphate (2,3,4,5) nucleotidase: orotate pyrD Glc-PP-Und α-(1,4)- (S)-malate TDP-N-acetylfucosamine:lipid II GDP guanosine-3',5'- hydratase: fadB solute or OmpN solute or ribonucleotide kinase: ndk kinase: ndk phosphate scpB Lipid A transglycosylase: phosphatase: aphA pentakisphosphate cytidine 3'- cpdB YfaZ LdrC PRPP glycine betaine TusD:TusE YdjE ion < 600 Da ion < 600 Da synthase: purK orotate deoxyuridine uracil fucosyltransferase: N-acetylfucosaminyltransferase: pyrophosphokinase: relA bis(diphosphate) 3'- phosphatase: palmitoyltransferase: mltG phosphohydrolase: nucleotidase: cpdB YdeR orotate dTTP dCTP GDP kinase: adk (S)-3-hydroxydodecanoyl-CoA a ring-opened 7- α-D-Fuc4NAc-(1->4)- enterobacterial 5-amino-6-(5-phospho- a peptide with a [protein chain (4S)-4-hydroxy- a peptide with 1-palmitoyl- 5'-deoxyribonucleotidase: kinase: tdk phosphorylase: wcaE wecF GDP diphosphokinase: spoT diphosphatase: spoT otsB sulfurtransferase: tusE MoO - 4-nitrobenzaldehyde S-methyl-L- FMN NAD(P)H H + pagP appA nucleoside 3'- methylguanine β-D-ManNAcA-(1->4) common antigen 2 an N-terminal (R)-β-lysine elongation factor PLP D-ala a tRNA precursor L-allo-threonine an N-terminal sn-glycerol AceF HipA BolA D-myo-inositol guanosine N5-CAIR phosphoribosyltransferase: deoA GDP kinase: ndk GTP D-ribosylamino)uracil L-homocysteine 2-oxoglutarate β-D-glucose UhpC (R)-lipoate dGMP ushA orotate a [TusE sulfur carrier molybdopterin 34 methionine monophosphate α α β α α a uridine 34 in tRNA 3-hydroxyacyl-CoA in DNA -GlcNAc-PP-Und molybdopterin 4-nitrobenzaldehyde Xaa-L-proline P]-L-lysine L-methionine 3-phosphate a mature peptidoglycan a nascent peptidoglycan (2,3,4,5) a nucleoside Tsx a nucleoside glycine pyrE dUMP -L-Fuc-(1->4) -D-Fuc4NAc-(1->4)- -D- O-antigen building blocks biosynthesis (E. coli) , -trehalose 6-phosphate acyl-CoA:1-acyl- serine/ 2+ 2+ deoxyribonucleoside 5 phosphoribosyltransferase: GDP protein]-S-sulfanylcysteine dehydrogenase: Nucleoside and Nucleotide Degradation cofactor Pb Pb a hepta-acylated core γ phosphatase: aphA N -carboxyaminoimidazole 2-deoxy-α- -2/3-O-Ac-α-L- ManNAcA-(1->4)-GlcNAc-PP-Und reductase: dkgB sn-glycerol-3- threonine a 2-acyl-1-lyso- with (L-alanyl- -D-glutamyl- (meso-DAP containing) 5'-monophosphate tetrakisphosphate glycine betaine ABC glycine pyrE malate 5-amino-6-(D- FMN 2-keto-4- Cd 2+ ZntA Cd 2+ cytidine ribonucleotide α α α fadB aldehyde reductase: yqhD D-alanine deoxyguanylate phosphatidylethanolamine oligosaccharide lipid meso-2,6-diaminopimeloyl- with GlcNAc terminus SfmA betaine transporter, non- betaine D-ribose 1- UDP- -D- Fuc-(1->3)- - dehydrogenase: lipid III UDP- -D-galactose α 5-(methoxycarbonylmethoxy) DNA- enterobacterial proline EF-P-lysine homocysteine S- reductase: hydroxyglutarate L-allo- methionine phosphate 2-O- kinase: 2+ 2+ phosphatase: yfbR BcsC ECA -D-glucopyranose 1-phosphate D-glucopyranose 6-phosphate tRNA-specific 2- ribitylamino) RNase D lipoate-AceF Zn Zn A (E. coli K-12 type) a 2'- mutase: purE orotidine 5'-phosphate UDP-galactopyranose 3-hydroxyacyl-CoA superpathway of pyrimidine common antigen bis(molybdenum aldehyde reductase: yahK aminopeptidase: methyltransferase: transaminase: threonine aminopeptidase: acyltransferase: kinase: gmk hipA D-alanine) tetrapeptide N,N',N''- N,N',N''- osmoregulatory phosphate galactose D-Glc-PP-Und mdh flippase: wzxE glucose-6-phosphate thiouridylase: mnmA uridine biosynthesis superpathway of purine deoxyribonucleosides degradation guanosine nucleotides pseudouridine formamidopyrimidine uracil lysyltransferase: fre aldolase: eda ligase: lplA phosphorylated orotidine 5'- malate glucose-1-phosphate dehydrogenase: deoxyribonucleosides degradation adenosine cofactor) glyA exonuclease: rnd deoxyribonucleoside ChiP thymidine α β mutase: glf glycosylase: mutM polymerase: wzyE aldehyde reductase: ahr pepP epmA mmuM aldolase: ltaE map plsC serine/threonine- 2+ triacetylchitotriose triacetylchitotriose CAIR malate -D-Fuc4NAc-(1->4)- -D- isomerase: pgi degradation III degradation glycosidase: 1-palmitoyl-2- BolA-phosphate 2+ Zn ABC 2+ orotidine-5'- phosphate α malate dehydrogenase UDP-Galf thymidylyltransferase: rffH fadJ nucleotides synthase: mobA + dGDP Zn Zn YicS phosphorylase: superpathway of guanine and guanosine salvage UDP-Gal: -L-Fuc-(1->4)- 2'-deoxycytidine NADP -dependent palmitoleoyl- protein transporter dehydrogenase ManNAcA-(1->4)-GlcNAc-PP-Und glucose-6-phosphate 34 SAM ybiA phosphate α dehydrogenase: (oxaloacetate- glucose-1-phosphate a 2-thiouridine in tRNA degradation II + phosphoribosylaminoimidazole- orotidine-5'- ppnP 2/3-O-Ac- -L-Fuc-(1->3) prephenate pseudouridine a [DNA]- 2,6-diamino-4- enterobacterial di-trans,octa-cis aldehyde reductase: ybbO a peptide with [a protein chain NAD(P) FMNH glyoxylate pyruvate sn-glycerol kinase HipA an osmoregulated di-trans,octa-cis α-D-Kdo-(2->4) D-myo-inositol YfaL (oxaloacetate- enterobacterial isomerase: kduI 3-oxododecanoyl-CoA 2'-deoxyguanosine a 5'-phospho- pyridoxamine pyruvate a nucleoside 5'- 2 an (S-diacyl-sn- a LolA-lipoprotein an L-1-phosphatidyl- + decarboxylase: pyrF -α-D-Glc-PP-Und α-(1,3) maeB decarboxylating) thymidylyltransferase: deoxycytidine GMP nucleotide- hydroxy-5-(N-methyl) 4-oxo-2-pentenal -undecaprenyl bis(guanylyl a proteinogenic a tRNA acetaldehyde AceF-lipoate periplasmic glucan -undecaprenyl α (2,3,4,5) NADP succinocarboxamide phosphate thymidine decarboxylating) F6P AMP pseudouridine [DNA] common antigen 4-nitrobenzyl alcohol an N-terminal elongation factor met 5'-phosphate monophosphate gly met a peptide UhpC-glucose-6-P 3-phosphate Zn 2+ ZitB Zn 2+ sn-glycerol - -D-Kdo-(2->6) putative : maeA common antigen rfbA D-ribofuranose amino acid glyceryl)-L-cysteinyl- complex IMP + YaiO decarboxylase: guanosine -galactosyltransferase: 5-carboxymethylaminomethyluridine- 3-ketoacyl-CoA deaminase: cdd 2'-deoxyadenosine AMP guanosine-5'- 3'-phosphate formamidopyrimidine diphosphate molybdopterin) L-proline β a phosphoglyceride diphosphate -lipid A (E. coli) tetrakisphosphate NADP synthase: purC UMP phosphorylase: : maeA polymerase: wzyE dTDP-α-D-glucose carboxy-S- kinase: psuK 5,6-diaminouracil EF-P]-N-( -L- [apolipoprotein] D-myo-inositol multidrug wcaC tRNA synthase: mnmE mnmG cofactor 5-phosphate 34 IMP phosphatase: phosphatase: sulfadiazine sulfadiazine YcaM pyrF deoA L-glutamine--D- adenosyl-L- thiolase: fadA thymidine phosphatase: phosphate pseudouridine lysyl)-L-lysine (2,3,4,5) efflux pump SAICAR dTDP-glucose 4,6- 2'-deoxyuridine deoxyguanosine 2+ 2+ lipoprotein phoA phoA UMP kinase: pyrH enterobacterial common antigen fructose-6-phosphate a 5-carboxymethylaminomethyl- methionine acetyl-CoA C- phoA phosphohydrolase: 5'-phosphate Zn ZntB Zn tetrakisphosphate MdtNOP UMP α 34 apolipoprotein N- YpjA thymidine -D-Gal-(1->3) dehydratase: rfbB aminotransferase: glmS 2-thiouridine in tRNA acyltransferase: thymidine deoxyadenosine phosphorylase: yrfG chaperone nucleoside 5'- NADP 5'-phosphoribosyl-4-(N- guanosine α synthase: adenosine a 7,8-dihydro- a 5'-deoxyribose- RNase III mRNA a 5'-half-tRNA iron(III)-[N-(2,3- a [protein] N- L-glycero- acyltransferase: lnt phosphohydrolase: UDP UMP - -L-Fuc-(1->4) dTDP-4-dehydro-6- tRNA 5-aminomethyl- phosphorylase: deaminase: add deoD 5'-nucleotidase: umpG pseudouridine- 1-cis-vaccenoyl-sn- L-threo-3- KdpD-N- LolB: lolB monophosphate phosphatase succinocarboxamide) thymidine phosphorylase: ppnP cmoA fadI 8-oxoguanine 5-phosphate- glycerophosphoglycerol processing H O ATP methyl red molecule with dihydroxybenzoyl) terminal-formyl- 1-butanesulfonate trimethylamine citrate L-galacto- DinJ-YafQ D-myo- appA ferric -2/3-O-Ac-α-L- deoxy-α-D-glucopyranose D-glucosamine 6-phosphate ppnP deoxyadenosine 5'-phosphate 2 a 3'-half-tRNA glycerol-3-phosphate TorT PhoB phospho- SucB (R)-lipoate adenine phosphatase: aphA MliC kinase: kinase: tdk 2-thiouridine UMP phosphatase: dATP phenylserine NAD + DedA -5-aminoimidazole guanosine guanosine Fuc-(1->3)-α- oxaloacetate phosphorylase: glycosidase: in DNA [DNA] substrate molecule with a 2',3'-cyclic -L-serine] complex L-methionine acyl-CoA:1-acyl- N-oxide L-histidine octuluronateL-glycero- YqjA an N-acyl-(S-diacyl- an osmoregulated inositol (2,4,5) coprogen pyrH dTDP-4- synthase: mnmC decanoyl-CoA thymidine deoxyinosine adenosine umpH pyrophosphohydrolase: a LolA lipoprotein a 1,2-diacyl-sn-glycerol α-D-Kdo-(2->4) di-trans,octa-cis inosine lyase: purB dTMP kinase: gsk phosphorylase: xapA phosphoglucosamine a 5- S-adenosyl-S- deoD a 5'-OH end phosphate end sn-glycerol-3- sn-glyceryl)-L- periplasmic glucan trisphosphate iron(III)- outer iron(III)- UDP reductase: D-Glc-PP-Und 34 psuG L-galacto- adenine α YadN galactosyl-(1->3)-L-fucosyl- dehydrorhamnose a 5-(aminomethyl)-2- hydroxyuridine carboxymethyl- uracil phosphorylase: 2'-deoxyinosine phosphorylase: deaminase: add nucleoside 5'- glycerophosphoryl diester ATPase: ychF FMN dependent nudB alkanesulfonate chaperone - -D-Kdo- -undecaprenyl UDP guanosine pyruvate mutase: glmM acyl-CoA DNA- DNA-5'-terminal ferric-chelate peptide phosphate 2-O- citrate lyase: octuluronate deaminase: cysteinyl-[lipoprotein] with phosphoglycerol coprogen membrane coprogen AICAR nrdA nrdB guanine (1->4)-O-acetyl-L-fucosyl- phosphoenol 3,5-epimerase: rfbC 34 phosphorylase: deoA deoD uracil phosphodiesterase: glpQ ribonuclease NADH- monooxygenase: phenylserine lipoate-SucB (2->6)-lipid A phosphate UDP kinase: adk phosphorylase: deoD thiouridine in tRNA in tRNA L-homocysteine dehydrogenase: monophosphate RadD nucleoside triphosphate citD citF citE substituent transport UDP phosphoribosyltransferase: hpt β pyruvate α deoA formamidopyrimidine deoxyribophosphodiesterase: III: rnc azoreductase: 2'-5' RNA reductase: deformylase: acyltransferase: ssuD L-glycerokinase:- ydjH adeD 1-diphosphate UDP kinase: ndk (1->3)- -D-glucopyranosyl- dTDP-4-dehydro-β-L-rhamnose -D-glucosamine 1-phosphate tRNA 5-aminomethyl- phosphatase: aphA glycerophosphoglycerol ATPase: radD pyrophosphohydrolase: aldolase: ltaE ligase: lplA complex DjlB AICAR kinase: adk fadE thymine inosine purine ribonucleosides degradation glycosylase: mutM mutM ligase: nfeF def 1-cis-vaccenoyl-plsC L-galacto- DinJ-YafQ- guanine diphosphoundecaprenol carboxykinase phosphoenolpyruvate colanic acid building blocks biosynthesis tRNA U34 2-deoxy-α-D- guanosine phosphodiesterase: ugpQ ATPase: lhr azoR mazG OsmB YceK transformylase: dUDP 2-thiouridine thpR hypoxanthine phosphate UDP superpathway of 5-aminoimidazole phosphoribosyltransferase: gpt acetyltransferase: wcaB (ATP): pck synthetase: ppsA dTDP-4- glucosamine- carboxymethyltransferase: (2E)-dec-2-enoyl-CoA ribose 1-phosphate 2-palmitoleoyl-sn- octuluronate- ferric GMP α methyltransferase: inosine RNase III dAMP acetate oxaloacetate an L-1- an (S-diacyl-sn- lipid A-core trimethylamine α-D- purH kinase: ndk ribonucleotide biosynthesis guanine 2-O-Ac- -D-Gal- D-glucopyranose dehydrorhamnose 1-phosphate cmoB a [DNA]- 4-hydroxy- N-(2,3- glycerol-3-phosphate 1-butanal sulfite 1-phosphate a 1-palmitoyl-2-acyl-sn a reduced a ribonucleoside O-phospho- deoxyribose 1,5- guanosine a 5'-phospho- 7,8-dihydro- a 5'-phospho- an mRNA fragment 2+ an N-terminal L- benzaldehyde glyceryl)-L-cysteinyl- citrate outer dUDP kinase: ndk gln (1->3)-α-L-Fuc- mnmC phosphorylase: 4-oxo-2-pentenal processing N,N-dimethyl-1,4- Fe formate gly TorT-TMAO KdpD asp53 SucB-lipoate phosphatidylethanolamine oligosaccharide (E. N-oxide glucopyranose iron(III) iron(III) gln 6-phosphate reductase: rfbD acetyltransferase: glmU enoyl-CoA adenosine nucleotide- [DNA] 8-oxoguanine [DNA] 2-pentenal- glycerol ADP H + anthranilate dihydroxybenzoyl) methionyl-[protein] PhoB-P -glycerol 3-phosphate TorC protein 5'-monophosphate L-tyrosine membrane FAICAR UTP phosphoenolpyruvate phosphomutase: phosphorylase: ppnP sn-glycerol 3-phosphate product mRNA phosphate phenylenediamine a ligated tRNA Na + Na + [apolipoprotein] coli K-12 core type) 1-phosphate YedA PRPP (1->4)-2/3-O-Ac- a 5-[(methylamino)methyl]- hydratase: fadJ 2-deoxy-α- ppnP 3'-phosphate 5-phosphate -L-serine nucleoside 5'- glucose-1- O-phospho- dicitrate dicitrate UTP dTDP-β-L-rhamnose a 5-(carboxymethoxy) uracil + ChaA + transport dUTP superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) α-L-Fuc-(1->3)- UDP-α-D- N-acetyl-α-D-glucosamine 1-phosphate 2-thiouridine 34 in tRNA deoB guanosine with a 2'-5' linkage K K monophosphate IMP glucose-6- phosphoglucomutase: uridine 34 in tRNA enoyl-CoA D-ribose 1- inosine adenosine phosphatase: L-tyrosine complex CTP amidophosphoribosyltransferase: purF α-D-Glc-PP-Und glucuronate 2-deoxy-D-ribose phosphorylase: xapA apolipoprotein N- Lipid A trimethylamine phosphatase: aphA phosphatase: YchO cyclohydrolase: CTP synthetase: pyrG dUTP enolase: eno phosphate pgm tRNA 2-selenouridine 5 hydratase: fadB phosphate phosphorylase: deaminase: agp synthetase: CTP β N-acetylglucosamine- tRNA cmo U34 5-phosphate guanosine dequalinium dequalinium acyltransferase: lnt palmitoyltransferase: N-oxide purH pyrophosphohydrolase: 5-phospho- - isomerase: synthase: selU deoxyribose 1,5- xapA add 5'-ribonucleotidase: phosphosugar aphA a long-chain a long-chain 1-phosphate methyltransferase: 10 RNase E mRNA a peptide with a PepB a 2'- a [protein]-L- a DNA with FadL pyrG UDP-glucuronate:2- α-D- (S)-3-hydroxydecanoyl-CoA phosphorylase: deoD an N - + (2R,3S)-3- a [protein]-L- a dipeptide with a D-ribulose ethidium ethidium pagP reductase: torA YoaE nudI D-ribosylamine adenine and adenosine salvage II phosphomutase: an L-methionyl- a long-chain fatty acyl- NADP a reduced 5 an inactive ushA tyr fatty acid fatty acid CTP 2-phospho-D-glycerate pgi uridyltransferase: glmU cmoM inosine glutathione 2-hydroxyethyldisulfide a malonyl-[acp] processing 3-chloro-D-alanine deoxyribonucleoside a RNA-DNA hybrid glutamate-O Tyr asp MdfA phosphatase: β a 5-methylaminomethyl-2-(S- deoxyribose- Met formyltetrahydrofolate thioglycolate an N-terminal aminopeptidase [DNA] isopropylmalate β-isoaspartate C-terminal L-proline D-tyrosyl-tRNA 5-phosphate trp unresolved CheB-P a drug a drug dUTP O-Ac- -D-Gal-(1->3)- glucopyranose deoB phosphorylase: inosine guanosine [initiator tRNA ] [acyl-carrier protein] flavodoxin Der GTPase an N-acyl-(S-diacyl- a ribonucleoside phoA IMP CTP phosphoribosylamine--glycine α glucose-6- α geranyl)thiouridine 34 in tRNA a 5-(methoxycarbonylmethoxy) 3-hydroxyacyl-CoA phosphate substrate Xaa-L-proline substrate 5'-triphosphate (2S)-2- protein-L- -methyl-ester D-ribulose 5- recombinational a 2-acyl-1-lyso- -L-Fuc-(1->4)-2/3-O 2,3-bisphosphoglycerate- 1-phosphate UDP-N-acetyl- -D-glucosamine 2-deoxy-D-ribose guanine Der [+ 2 more] [+ 2 more] sn-glyceryl)-L- a hepta-acylated core diphosphatase: dut ligase: purD 34 deoD isopropylmalate isoaspartate(D- phosphate 1- phosphatidylethanolamine a 2-acyl-sn-glycerol D-glucopyranose CDP -Ac-α-L-Fuc-(1->3)-β- phosphate uridine in tRNA dehydrogenase: aldolase: deoC GTPase- or Holliday an oxidized trimethylamine independent UTP--glucose- tRNA 2-selenouridine 5-phosphate 2-hydroxyethyldisulfide Xaa-Pro + cysteinyl-[lipoprotein] oligosaccharide lipid nucleoside triphosphate adenosine isomerase: fadB β flavodoxin- RNase: rnhB hydro-lyase (2- aspartate) O- dehydrogenase: junctions, K 3-phosphate N-acetylneuraminate NanC N-acetylneuraminate EcpC D-Glc-PP-Und β-(1,3)- 10-formyltetrahydrofolate:L- -ketoacyl [acyl- 3-chloro-D-alanine DNA protein-glutamate Tyr activating TorC protein YihN CDP CDP GAR adenosine phosphoglycerate 1-phosphate synthase: selU hypoxanthine reductase: yghU ribonuclease: aminopeptidase: + aminopeptidase: dipeptidase: D-Tyr-tRNA tryptophanase: + + A (E. coli K-12 type) pyrophosphohydrolase: kduI guanine xanthosine adenosine inosine guanosine fMet NADP ribonuclease: rnhA isopropylmaleate- methyltransferase: methylesterase: yajO created by RecADNA K transporting K 2'-deoxycytidine glucuronosyltranferase: 3-hydroxyacyl-CoA methionyl-tRNA N- carrier protein] rne dehydrochlorinase: polymerase: 1-deoxy-D- protein: yihI mazG reductase: nucleosidase: mutase: gpmM uridylyltransferase: a 5-methylaminomethyl-2-(Se- deoxyribose- acetaldehyde D-glyceraldehyde 3-phosphate deaminase: guaD 2-hydroxyethyldisulfide pepA reductase: pepB forming): leuC leuD pcm pepQ deacylase: dtd tnaA P-type ATPase inosine 5'- CDP reductase: diphosphate:oxidized wcaA dehydrogenase: phosphorylase: phosphorylase: formyltransferase: fmt synthase: fabB dcyD dinB β cheB helicase: nrdA nrdB phosphoribosylglycinamide phosphoribosylglycinamide rihC galU 34 reductase: yfcG (2S)-2- a protein L- - xylulose 5- a Der GTPase CheB nrdA nrdB NrdH glutaredoxin-like phospho)selenouridine in tRNA phosphate hypoxanthine ppnP ppnP fpr recG an osmoregulated an osmoregulated lipid A-core trimethylamine a UDP-sugar monophosphate dUMP 3-phospho-D-glycerate fadJ acetaldehyde isoaspartate phosphate K + + a 1-palmitoyl-2-acyl- a reduced a ribonucleoside formyltransferase 2: purT formyltransferase 1: purN adenine F6P aldolase: xanthine a nucleoside 5'- isopropylmalate a DNA segment KefC K oligosaccharide (E. dehydrogenase: protein oxidoreductase: ribonucleoside- β UDP-α-D-glucose tRNA 2-selenouridine hydroxylase: xanthosine adenosine inosine guanosine an N-formyl- RNase E a peptide with DNA α a proteinogenic periplasmic glucan periplasmic glucan with phosphatidylglycerol N-oxide a protein YraJ YbaN ribonucleoside- thymidylate -D-GlcA-(1->3)- deoC dehydrogenase a proteinogenic a proteinogenic -methyl ester pro a [protein]-α- TorY protein 3'-phosphate nrdE nrdF diphosphate phosphoglycerate synthase: selU 3-oxodecanoyl-CoA xdhA xdhB xdhC a tetrahydrofolate 2-sulfanylethan- an mRNA fragment processing S-carboxymethyl- an N-terminal a peptide [DNA] monophosphate MeOH D-tyrosine a tRNA Tyr indole pyruvate phosphoglycerol substituent coli K-12 core type) guaB diphosphate FGAR 2-O-Ac-α-D-Gal- mannose-6- (acetylating) xanthine:NAD+ phosphorylase: phosphorylase: phosphorylase: phosphorylase: L-methionyl- a long-chain 3-oxoacyl-[acp] NADPH an oxidized H + amino acid nucleoside 3'- UDP-sugar YdiY synthase: thyA uracil degradation III GSSG amino acid amino acid L-glutamate + + tail-specific reductase: met 1-ol product mRNA D-cysteine L-proline K KefB K reductase: nrdE nrdF adenine (1->3)-α-L-Fuc- kinase: pgk phosphate UDP-glucose 6- a 5-methylaminomethyl-2- : mhpF pyrimidine ribonucleosides oxidoreductase: ppnP ppnP xapA xapA [initiator tRNA ] flavodoxin monophosphate hydrolase: nrdE nrdF UDP- tRNA processing 3-ketoacyl-CoA D-glyceraldehyde xanthine protease: dTMP phosphoribosylformylglycinamide phosphoribosyltransferase: apt isomerase: 34 acetaldehyde xdhA xdhB xdhC phosphoglycerol Lipid A trimethylamine phosphatase: aphA dCDP (1->4)-3-O-Ac- glucose 4- dehydrogenase: selenouridine in tRNA thiolase: fadA 3-phosphate uracil acetaldehyde degradation xanthosine adenosine inosine guanosine ushA prc synthetase: purL α α-L-Fuc-(1->3)- 13-DPG manA transferase: opgB palmitoyltransferase: N-oxide dCDP UDP- -D- epimerase: ugd dehydrogenase: xanthine:NAD+ phosphorylase: phosphorylase: phosphorylase: phosphorylase: + + 3'-nucleotidase: YcaP AMP a polycistronic acetyl-CoA C- acetaldehyde cytidine urate 1 K Kup K dCDP kinase: adk dTMP kinase: tmk α-D-Glc-PP-Und D-mannopyranose uracil xapA an N - an α- 3-O-β-D- a [lipoyl-carrier a non-methylated [a protein chain an [RNA]-3'- (2E,11Z)- a protein-L- pagP reductase: torZ cpdB a peptide XMP UDP galactose galE acyltransferase: adhE oxidoreductase: deoD deoD deoD a sulfurated a ribonucleoside GDP-α-D-glucose a dipetide with an N- α YpjB dCDP kinase: ndk FGAM glyceraldehyde- UDP-α-D- tRNA precursor dehydrogenase oxygenase: rutA dethiobiotin SAM 2-oxoglutarate methyladenine 2-oxoglutarate 1-methyl-dAMP D-glucose 1-phosphate a type IV prepilin deoxyadenosine galactopyranosyl- protein]-N 6 -[(R elongation factor EF-P]- NADH ribonucleoside- methionine- an -D-aldose UMP dCDP 6-phosphate cytidine xdhA xdhB xdhC [sulfur carrier] formate triphosphate ribosomal terminal L-aspartate L-selenocysteine octadecenoyl-CoA lys a protein an osmoregulated an osmoregulated a ribonucleoside dTDP 2'-deoxyuridine 5'- triose- 3-phosphate α glucuronate galactose degradation I (Leloir pathway) fadI (acetylating) acetaldehyde N-(β-L-lysyl)-L-lysine 34 3'-phosphate enoyl-CoA (S)-S-oxide 1-phosphate YjbH UDP-Gal:β-D-GlcA- UDP- -D- deaminase: α-D-ribose- in RNA sugar phosphatase: ybiV in DNA D-arabinose )-lipoyl]-L-lysine protein L11 RNA 3'- K + TrkG K + periplasmic glucan with periplasmic glucan a hepta-acylated core xanthosine-5'- dCTP kinase: adk formate UDP phosphomannomutase: (Z)-3-ureidoacrylate dehydrogenase: ribosomal EF-P-Lys34 lysine 2,3- protein- serine a 2-acyl-1-lyso- an oxidized UTP diphosphate:oxidized phosphoribosylformylglycinamide (1->3)-2-O-Ac-α-D-Gal- phosphate dehydrogenase: galactose ribonuclease: : mhpF cdd urate 1-phosphate sugar phosphatase: hxpA hydratase: oligosaccharide lipid trimethylamine phosphate:L- dCDP reductase: cpsG β-D- octanoyl-CoA 1-methyl-dAMP GDP-glucose protein L11 NADH terminal methionine- phosphoglycerol substituent phosphatidylglycerol YjcB dTDP kinase: adk CTP NrdH glutaredoxin-like cyclo-ligase: purM isomerase: gapA acetaldehyde eutE biotin hydroxylase: fadJ aminomutase: protease: TorY protein glutamine nrdA nrdB (1->3)-α-L-Fuc-(1->4)-3- galactopyranose rne α-D-ribose 1,5- N1- sugar phosphatase: yidA leader galactoside- ribonucleoside- glucosyl methyltransferase: dipeptidase: phosphate A (E. coli K-12 type) kinase: ndk uridine demethylase: endonuclease lipoamidase: pyrophosphatase: S-oxide + + dTDP kinase: ndk reductase: protein oxidoreductase: α α tpiA α-D-mannose acyl-CoA dehydrogenase: synthase: methyladenine epmC pepE selenocysteine epmB lon K TrkH K amido- UTP O-Ac- -L-Fuc-(1->3)- - D-glyceraldehyde galactose-1- α ureidoacrylate acetyl-CoA pyrimidine deoxyribonucleotides dephosphorylation phosphomutase: alkB phosphosugar peptidase: arabinose triphosphate hydrolase: gmm a methylatedprmA a [protein chain elongation nudC an [RNA]-3'-cyclase: rtcA enoyl-CoA reductase: nrdD nrdE nrdF AIR DHAP 1-phosphate -D- a tRNA precursor dehydrogenase: bioB IV: nfo cobB lyase: sufS YdeT asp reductase: D-Glc-PP-Und α-(1,4)- 3-phosphate adhE amidohydrolase: deoB demethylase: phosphatase: yigL gspO galactohydrolase: reductase: nrdD factor EF-P]-N-(β-lysyl) hydratase: β ligase (AMP- dTTP dCTP epimerase: glucopyranose uridine dCTP ribosomal ribonucleoside-2',3'- (R)- -lysine msrA a peptide 4,6-pyr-α-D- lipid A-core N-acetyl-muramoyl-(L- a (1->4)- a [protein]- with a 5' fadE alkB 34 a 1-palmitoyl-2-acyl- guanosine 2'- forming): guaA nrdD galactosyltransferase: mannose-1-phosphate galM ribonuclease: acetaldehyde rutB glucose 1-phosphate lacZ -5-hydroxy-L-lysine cyclophosphate fadB a [protein]-L- γ S-hydroxy- OmpX dUDP 1-phosphate extension and exoribonuclease phosphorylase: pyrophosphohydrolase: nudI D-ribose 5- protein L11 reduced β- (S)-3-hydroxy-(11Z) Gal-(1->4)-β-D- oligosaccharide (E. phosphatidylserine alanyl- -D-glutamyl-L- α-D-glucan Aer wcaL guanylyltransferase: dehydrogenase: an unsulfurated an N-terminal a 5'-α- a 2'- GDP D-glucopyranose a proteinogenic methionine monophosphate adenylosuccinate superpathway of pyrimidine dCTP ADP-L-glycero-β-D-manno α-D- II: rnb rne (2E)-oct-2-enoyl-CoA ppnP phosphate biotin 5'-deoxyadenosine formaldehyde succinate phosphatase: phoA a [protein] C- a [DNA]-3'- a [lipoyl-carrier asp AMP nicotinamide D- YhhH GlcA-(1->3)-2- coli K-12 core type) lysyl-D-alanyl-D-alanine) L-cysteine cpsB UTP--glucose- a long 3' trailer eutE nucleoside triphosphate met dAMP deoxyadenosine-5- (R)-lipoate amino acid selenide -octadecenoyl-CoA 2'GMP protein GMP nucleobases salvage deaminase: dUDP galactopyranose [sulfur carrier] D-glucopyranose L-phenylalanyl- hydroxyl β-D- deoxyribonucleoside protein]-L-lysine ala α synthetase: purA α -heptose biosynthesis polynucleotide carbamate (Z)-3-aminoacrylate uridine pyrophosphohydrolase: formaldehyde an adenine in RNA succinate terminal glycine D-arabinose ribonucleotide O-Ac- -D-Gal- sulfenic acid dcd α-D-Gal-(1->4)- fructose- GDP- -D- 1-phosphate enoyl-CoA [type IV prepilin] phosphate-[DNA] 5'-triphosphate α-amylase: phosphatase: kinase: ndk phosporylase: phosphorylase: mazG adenosine galactopyranose (1->3)-α-L-Fuc- Lipid A D-alanyl-D-alanine uracil β-D-GlcA-(1->3)- bisphosphate mannose D-sedoheptulose galactokinase: uridylyltransferase: hydratase: fadJ acetyl-CoA malS phoA reductase: YfiB pnp putative 3-aminoacrylate udp dCTP dCMP nucleotides (1->4)-3-O-Ac- palmitoyltransferase: carboxypeptidase: YqjD guanylate adenylo-succinate uracil 2-O-Ac-α-D-Gal- aldolase: fbaB GDP- 7-phosphate galK galU ethidium TehA ethidium dsbG dUTP D-sedoheptulose enoyl-CoA carbamate degradation III 1 α a [protein]- EcnA phosphoribosyltransferase: upp RNase D deaminase: rutC 2503 an N - cyclic 2''-O-acetyl- a protein-L- -L-Fuc-(1->3)-colanic acid pagP dacC kinase: gmk (1->3)-α-L-Fuc- adenine a [lipoyl-carrier 4 RNase II poly-A (2E,9Z)- guanosine fructose mannose 4,6- 7-phosphate α-D-galactose hydratase: fadB decarboxylase: α 2-oxoglutarate 2-oxoglutarate 1-methyl-dATP a hexose phosphate an alkylated DNA (R)-lipoate N -acetylcytidine α-D-Glc-PP-Und(E. coli K-12) L-cysteine adenylosuccinate adenine and UMP dUTP UDP-α-D-glucose exonuclease: -D-ribose- uracil dUTP AMP in 23S rRNA methyladenine a tRNA precursor MoaD-S pyranopterin SucB-lipoate protein]-L-lysine RplL thr substrate mRNA ADP-ribose met hexadecenoyl-CoA L-homoserine methionine- a protein a (1->4)- (1->4)-3-O-Ac- bisphosphate dehydratase: isomerase: gmhA 1-phosphate RNase BN a tRNA precursor rutD 3-oxopropanoate 2-oxoglutarate dGTP maltohexaose GDP lyase: purB adenosine pyrophosphohydrolase: salvage pathways of pyrimidine ribonucleotides D-glycero-D- rnd 1-phosphate pyrophosphohydrolase: nudI AMP in DNA sugar phosphatase: ybiV phosphate enoyl-CoA (R)-S-oxide attached to a hepta-acylated core N-acetyl-muramoyl-(L- α-D-glucan α-L-Fuc-(1->3)- aldolase: fbaA gmd ribonuclease: with a 5' (S)-3-hydroxyoctanoyl-CoA ribosomal-protein- threonine protein- a 2-acyl-1-lyso- salvage V UMP kinase: pyrH manno-heptose α nucleosidase: L-amino acid N- hydratase: homoserine YhhT lipid anchor γ nudI α S-methyl-5'-thioadenosine CO -D-ribose 1,5- dUTP diphosphatase: dut 2 sugar phosphatase: hxpA nucleoside triphosphate 4 protease: oligosaccharide lipid alanyl- -D-glutamyl- D-ala PdeG -D-Glc-PP-Und rbn 2 malonic 1-methyl-dATP DNA-3- L12-serine dehydratase: tdcB N -acetylcytidine 2''-O-acetyl- methionine- phosphatidylserine AMP colanic acid GDP-4-dehydro- 7-phosphate extension and a 3-hydroxyacyl-CoA ppnN 23S rRNA m A2503 lipoate--protein acyltransferase: fadJ racemase: QseG xanthine and xanthosine salvage dUTP cytidine α degradation IV semialdehyde phosphomutase: nucleoside triphosphate N1- sugar phosphatase: yidA pyrophosphohydrolase: acetyltransferase: exoribonuclease ADP-ribose S-oxide ptrA A (E. coli K-12 type) L-lysyl-D-alanine) UDP pyruvoyl -D-rhamnose heptose 7- RNase D short 3' extension methyltransferase: demethylase: endoribonuclease methyladenine ligase A: lplA threonine amidohydrolase: mnaT ygeA adenine diphosphatase: dehydrogenase: deoB pyrophosphohydrolase: AMP methyladenine phosphosugar mazG rimL II: rnb deacetylase: enoyl-CoA YghG adenylate transferase: GDP-L- phosphate exonuclease: S-methyl-5'- reductase: ydfG rlmN alkB BN: rbn glycosylase: alkA deaminase: ilvA yqfB reductase: GDP adenosine UDP kinase: adk dut cytidine cytidine β RNase D fadB D-ribose 5- mazG nucleosidase: demethylase: phosphatase: yigL 50S ribosomal N-acetyl-L- hydratase: kinase: adk wcaK -D-fructose 1,6- rnd phosphate- thioadenosine malonic 2-oxobutanoate ymdB D-homoserine msrB a peptide α-D-Kdo-(2->4)-α-D- D-myo- a 1,2-diacyl- GDP 2'-deoxyguanosine 5'- phosphorylase: UDP kinase: ndk cytosine deaminase: kinase: udk 4,6-pyr-α-D- fucose kinase: hldE exonuclease: dUTP dUMP alkB subunit protein L7 methionine fadB a [protein]-L- an L-1- dCMP YhfT reductase: xanthosine nucleoside triphosphate bisphosphate D-glycero-β-D- dependent 3-hydroxyacyl-CoA 5'-methylthioadenosine semialdehyde phosphate amn phosphosugar a [lipoyl-carrier dGMP RNase II YfgG a 5-L-glutamyl- inositol (2,4,5) sn-glycerol 3- PLP ppnP Gal-(1->4)-β-D- synthase: rnd 2503 a DNA containing cytidine (S)-3-hydroxy-(9Z) Kdo-(2->6)-lipid A (E. coli) phosphatidylethanolamine an amino acid kinase: adk diphosphate:oxidizednrdA nrdB cdd α ribonuclease: dehydrogenase: nucleosidase: mtn a 2-methyladenine an alkylated 6 AMP methionine [peptide] dCMP phosphatase: phoA ADP UTP xanthosine pyrophosphohydrolase: fructose-1,6- fcl manno-heptose UDP-glucose: - exonuclease: reductase: rutE 5'-deoxyadenosine formaldehyde succinate phosphatase: phoA a single-stranded an apurinic/ SucB-S- protein]-N -[(R acetate substrate with trisphosphateD-myo-inositol diphosphatediacylglycerol pyridoxal 5'- NrdH glutaredoxin-like adenosine CMP GlcA-(1->3)-2- UDP- RNase T fadJ adenine in 23S rRNA met dATP mature tRNA nucleobase molybdopterin MoaD acetate ADP-D-ribose -hexadecenoyl-CoA dCMP GDP phosphorylase: ppnP mazG 1,7-bisphosphate D-galactose- rph rnpB rnpA MTR 5-hydroxy-CTP an adenine in DNA formaldehyde succinate a hexose oligoribonucleotide apyrimidinic site )-lipoyl]-L-lysine no poly-A tail RhsD protein oxidoreductase: uridine O-Ac-α-D-Gal- bisphosphatase: GDP-4-dehydro- glucose 4- succinyldihydrolipoate (2,4,5) triphosphate pyrophosphate phosphate kinase: ndk 2'-deoxyadenosine 5'- phosphorylase: CTP synthetase: pyrG cytosine CMP D-glycero- 1-phosphate exonuclease: 3-hydroxypropanoate diphosphohydrolase: nudG phosphohydrolase: yfbR xanthosine dUMP (1->3)-α-L-Fuc- yggF 6-deoxy-β- polynucleotide 3-oxooctanoyl-CoA Ni 2+ Ni 2+ phosphohydrolase: phosphatase: phosphatase: YaiW nrdE nrdF diphosphate:oxidized ADP deoD β epimerase: rnt 5-hydroxy-CTP 5-hydroxy-CMP RcnA γ-glutamyltranspeptidase: 5'-deoxyribonucleotidase: YagU phosphorylase: xapA deaminase: kinase: -D-manno- uridylyltransferase: phosphorylase: 2+ 2+ reductase: adenosine CTP xanthine (1->4)-3-O-Ac- fructose 1,6- L-galactose galE a tRNA Co Co ggt D-myo- appA a 1,2-diacyl-pgpB phoA NrdH glutaredoxin-like thymidylate codA cmk heptose-1,7- galT pnp 3-ketoacyl-CoA ushA nrdA nrdB α-L-Fuc-(1->3)- bisphosphatase: GDP-L- precursor with a tRNA precursor a cytosine 2501 a pyrimidine a [lipoyl-carrier 1402 32 3-hydroxy-2,4- (2E,7Z)- (3R)-3- inositol (2,5) sn-glycerol pyridoxal protein oxidoreductase: synthase: thyA uridine an N-terminal a [DNA]-3'- + a 5'-phospho- + a ribonucleoside dTTP a cytidine a uridine hydrogen bisphosphate 7- thiolase: fadA an L-phenylalanyl- prephenate NAD NAD ATP H O a single oxalate formyl-CoA 6 a DNA:RNA duplex a [protein] Ser/Thr a reduced pre-crRNA 2'-deoxyribonucleoside uridine CDP α-D-Glc-PP-Undcolanic ybhA fucose with a short CheY-acetylated 2 ribonucleotide protein]-N -[(R) dioxopentyl hydroxybutanoyl- DsbB 7-O-[2-aminoethoxy(hydroxy) adenosine xanthine kinase: udk a 5' extension arginyl-[protein] Phe in 23S rRNA hydroxyl [DNA] triphosphate in 16S rRNA in tRNA peroxide tetradecenoyl-CoA bisphosphate 3-phosphate nrdE nrdF dTMP phosphatase: acetyl-CoA C- [tRNA ] stranded DNA dTTP thioredoxin α a 1,2-diacyl-sn-glycerol an α-(5-L- 5'-monophosphate dGDP deaminase: phosphoribosyltransferase: gpt phosphorylase: acid fructose-1,6- synthase: 3' extension -dihydrolipoyl]- 16S rRNA 2'-O tRNA Um32 protein phosphate enoyl-CoA CoA CRISPR RNA YiaD phosphoryl]- -D-Kdo-(2->4) YgiB CDP gmhB pyrophosphatase: yhdE Autoinducer- crotonyl- phosphatase: aphA PpiD GTP ppnP repeat unit fcl acyltransferase: L-lysine protein N 6 - -ribose C1402 kinase: yeaG hydratase: processing: -α-D-Kdo-(2->6)-lipid A glutamyl)- a peptide add dTMP kinase: adk bisphosphatase: D-glycero-β-D- 23S rRNA 5- pyrimidine- methyltransferase: CoA RzoR ATP fadI superpathway of L-arginine Amino Acid Degradation DNA CheY ATP dTTP formyl-CoA ATP- 2 degrading casA casB amino acid 2'-deoxycytidine dADP kinase: tmk uridine UMP pyrimidine nucleobases salvage II flippase: glpX manno-heptose ribonuclease: phosphate- RNase D L-asparagine L-lysine degradation I L-arginine degradation phenylalanyl- DNA 5'-nucleotide (dihydrolipoyl) methyltransferase: trmJ serine/ fadJ hydratase: XMP CDP 4,6-pyr-α-D- GDP-β-L-fucose and L-ornithine degradation L-tryptophan hydroxycytidine ligase: ligA pyrophosphatase: pyrophosphohydrolase: transferase: dependent protein: lsrG dGDP phosphorylase: wzxC rnpB rnpA dependent exonuclease: degradation I II (AST pathway) tRNA--protein deacetylase: primase: nucleosidase: lysine:NAD+ rsmI a 2'-O- threonine enoyl-CoA casC inosine dTDP kinase: ndk fructose-1,6- 1-phosphate hexanoyl-CoA degradation II C2501 ycaO frc a 2'-O- helicase: lhr 3,4,4-trihydroxy-5- paaZ Gal-(1->4)-β-D- α-D- exonuclease: rnd transferase: aat DNA cobB dnaG nudI a [lipoyl-carrier methyluridine 32 casD casE fluoride CrcB fluoride ferric GTP kinase: adk ATP udp cytosine bisphosphatase: fbp UDP-α-D- ppnN oxidoreductase: lpd methylcytidine 1402 protein phosphooxypentan- hydratase: DsbB a [protein disulfide uracil heptose 1-phosphate (via pyruvate) synthase: rlhA 6 crotonyl-CoA oxidized N-acetyl-9-O- pyridoxine iron(III) iron(III) dTDP CTP GlcA-(1->3)-2- glucopyranose rph arg ligase: ligB nucleoside triphosphate protein]-N -[(R in tRNA Ins(1,2,3,4,5,6)P Ins(1,2,3,4,5,6)P ferric citrate ABC reductase: dGDP dADP reductase: phosphoribosyltransferase: upp cytosine deaminase: codA galactose RNase T acyl-CoA asn lys arg in 16S rRNA kinase: srkA 2-one fadB crRNA arg a [reduced DsbD protein] isomerase] carrying acetylneuraminate 6 6 dicitrate dicitrate inosine O-Ac-α-D-Gal- F6P adenyltransferase: 1-phosphate 2''-O-acetyl- pyrophosphohydrolase: )-lipoyl]-L-lysine a single (S)-3-hydroxy-(7Z) 5'-phosphate enterobactin transporter nrdD kinase: ndk kinase: ndk nrdD kinase: adk exonuclease: dehydrogenase: asparaginase: iaaA trp L-phenylalanyl-L- + ssDNA/pppN(pN) a [protein] (L-serine/L- an oxidized H O arginine a disulfide bond D-myo-inositol iron(III)- iron(III)- α hldE Phe nicotinamide AMP diphosphate H a pyrimidine base D-ribose 5- formate oxalyl-CoA RNA 2 chloride ClcA chloride pyridoxine-5'- kinase: gsk uracil (1->3)- -L-Fuc- Fatty Acid and Lipid Biosynthesis a tRNA 2501 CheY ADP-ribose mazG stranded DNA thioredoxin -tetradecenoyl-CoA 3-phytase: outer CsgB dTDP β rnt fadE L-asparaginase: ansA lysine arginine N- arginyl-[protein] a 5-hydroxycytosine 3-phenyl-2- hybrid threonine) phosphate decarboxylase, hexakisphosphate enterobactin enterobactin uracil (1->4)-3-O-Ac- glucose-6- ADP-D-glycero- - arginine tryptophanase: AMP [DNA] NMN n -1 phosphate N-acetyl-9-O- phosphate membrane D-allose kinase: ndk uracil decarboxylase: ldcC in 23S rRNA oxopropanoate dTMP degradative: adiA phosphohydrolase: agp complex complex α-L-Fuc-(1->3)- phosphate D-manno-heptose (2E)-hexenoyl-CoA decarboxylase, L-asparaginase: ansB succinyltransferase: tnaA acetylneuraminate phosphatase: transport D-allose ABC D-allose phosphoribosyltransferase: upp lysine 2-aminoprop- appA D-myo-inositol dGTP dATP IMP dTTP α isomerase: pgi ADP-L-glycero-D- palmitate biosynthesis superpathway of phospholipid biosynthesis I (bacteria) asp astA chloride ClcB chloride arginine D-myo-inositol phoA transporter -D-Glc-PP-Und PRPP biosynthesis superpathway of unsaturated superpathway of lipopolysaccharide biosynthesis degradative: adiA 2-enoate esterase: nanS complex (type II fatty acid synthase) an uncharged decarboxylase: cadA 2 decarboxylase: pyridoxine (1,2,4,5,6)- UMP colanic acid glucose-6- mannoheptose 6- fatty acids biosynthesis (E. coli) enoyl-CoA L-ornithine N -succinyl- an N-terminal a Chi-site containing a RecA DNA 7,8-dihydrofolate a DNA-3'- an [RNA]-3'- a [protein]-α- 1-cis-vaccenoyl- an unstable (1,2,3,4,5)- cystine YijE cystine tRNA queuosine an L-phenylalanyl- NADPH H + oxaloacetate pyridoxamine O-succinyl-L- maltoheptaose a tripeptide an adenine in DNA acetaldehyde pyruvate FAD NADH H + (2E,6E)-farnesyl a dipeptide pentakisphosphate polymerase: epimerase: rfaD a (3R)-3- hydratase: fadJ superpathway of L-threonine metabolism L-arginine double stranded recombination deoxyribose- ribonucleoside- a protein sn-glycerol- RecA filament- Tar gln DsbB speA pentakisphosphate phosphate D-ribose 5- a (3R)-3- DHAP cadaverine L-lysyl-[protein] [tRNA Phe ] monoglutamate L-glutamate diphosphate a protein TatABC a protein wcaD β an acetoacetyl-[acp] hydroxytetradecanoyl- biosynthesis I (de novo) agmatine homoserine DNA adenine 3-phosphate DNA complex agmatine a [protein disulfide N-acetylneuraminate BglH isomerase: phosphate ADP-L-glycero- - UDP-N-acetyl- enoyl-CoA DNA with a blunt end and repair protein 5-phosphate 2',3'- chemotaxis protein acyl-CoA:1-acyl- farnesyl RecA filament- nonspecific protein- an [oxidized acetate LpoB colanic acid hydroxydecanoyl- α N-succinylarginine ATP-dependent zinc isomerase] with reduced kduI ribose-phosphate D-manno-heptose [acp] -D-glucosamine hydratase: fadB ornithine cadaverine methyltransferase: cyclophosphate diphosphate dipeptidase: YahC Aromatic Compound Biosynthesis (E. coli K-12) acetoacetyl-[acp] [acp] glycerol-3-phosphate preQ dihydrolase: astB 2-iminopropanoate pyridoxamine- maltodextrin tripeptide RNA 2',3'-cyclic methyltransferase: acetoin sn-glycerol-3- FAD DNA complex glutamine DsbD protein] diphosphokinase: prs 0 thr phenylalanyl- dihydrofolate yhdJ metalloendoprotease: L-cysteine residues Cell Structure Biosynthesis reductase: fabG 3-hydroxydecanoyl- dehydrogenase: gpsA agmatinase: decarboxylase: aminotransferase: patA phosphorylase: cheR phosphate 2-O- phosphatase: stabilisation: pepD glutaminase: ATP synthase attached to D-glucopyranose acyl-[acyl-carrier- 7-cyano-7- (S)-3-hydroxyhexanoyl-CoA N 2 -succinyl- exodeoxyribonuclease reductase: folA oxaloacetate O-succinylhomoserine 3'-phosphodiesterase: aminopeptidase: phosphodiesterase: hflC hflK ftsH synthesis: reductase: PRPP lipoprotein posttranslational modification speF tRNA--protein DNA adenine a [protein]-L- bacA / thiamin lipid anchor 6-phosphate a (3R)-3-hydroxybutanoyl-[acp] [acp] deazaguanine speB V: recD recC recB transaminase nfo malP pepT thpR poxB acyltransferase: fre recF a proteinogenic cheB H + H + enterobactin biosynthesis protein]--UDP-N- 5-aminopentanal L-ornithine transferase: aat dihydrofolate lyase: metB an [RNA]-3'- glutamate-O 5 (2E,6E)-farnesyl dehydrase: fabA sn-glycerol 3-phosphate 3-hydroxyacyl-CoA methyltransferase: plsC recR recO glu triphosphate lipid A-core oligosaccharide ω superpathway of (Kdo) -lipid A biosynthesis reductase: queF threonine threonine a peptide 1,2-bis-cis- a stabilized amino acid Tar DsbB an L-1- phosphoenol cysteamine 2+ 2 peptidoglycan maturation (meso-diaminopimelate containing) acetylglucosamine O- reductase: folM ribunucleoside- -methyl-ester phosphate oxidized H O H O N - Fe YjgL polymyxin resistance (3R)-3- preQ dehydrogenase: succinylornithine α dam synthase (E. coli K-12 core type) 2 pyruvate 2 (3R)-3- a [prolipoprotein]-L-cysteine 1 dehydratase: dehydrogenase: -D- 6 vaccenoyl- RecA filament- phosphatidylethanolamine GTP phosphocreatine S-phosphate OmpA YfeO peptidoglycan biosynthesis I (meso-diaminopimelate containing) acyltransferase: lpxA 5-aminopentanal L-cysteine transaminase: astC L-phenylalanyl- a double stranded DNA maltohexaose an N -methyladenine 2'-phosphate ferroxidase: a (3R)-3- chorismate hydroxybutanoyl- hydroxydecanoyl- fadB tdcB threonine pyruvate pyridoxal a [DNA]-3'- 2-deoxy-D-ribose glucopyranose a proteinogenic a dipeptide acetoin phosphatidate FADH NAD + DNA complex ATP synthase cysteamine lipid II (meso α tdh 2 Phe 2 UDP- -D- acyl-CoA:sn-glycerol- acyl-acp:sn-glycerol- dehydrogenase: patD degradation II N -succinyl- L-lysyl-[protein] a tRNA with a RecA protein 5,6,7,8- asp 2-oxobutanoate succinate in DNA creatine phosphate bfr hydroxytetradecanoyl- UDP-N-acetyl- D-ribulose [acyl-carrier protein] [acyl-carrier UDP-3-O-[(3R)-3- tRNA-guanine 3-hydroxyacyl-CoA aldolase: + hydroxyl 5-phosphate 1-phosphate amino acid / thiamin S-phosphate UDP-N-acetyl- diaminopimelate containing) glucuronate D-ribulose 5-phosphate 3-phosphate 1-O- 3-phosphate 1-O- threonine L-threonine NADP H + H + phosphoamidase: [acp] α-D-glucosamine 5-phosphate α isochorismate dehydratase: fabZ transglycosylase: tgt putrescine ltaE L-glutamate 5- loaded 3' overhang tetrahydrofolate triphosphate phosphoenolpyruvate phosphatase: ferroxidase: -D-glucosamine protein] hydroxymyristoyl]-N- dehydrogenase: deaminase: dehydrogenase: 5-aminopentanoate GTP phoA peptidoglycan UDP-glucuronate synthase: entC acyltransferase: plsB acyltransferase: plsB a 7-aminomethyl-7- cys semialdehyde synthase phosphatase: phoA cueO D-arabinose UDP-N-acetylglucosamine dehydratase: fabZ D-arabinose acetyl-α-D-glucosamine fadJ ilvA phosphohydrolase: phoA YhdU glycosyltransferase: dehydrogenase: 34 2-amino-3- yiaY 3+ hexane hexane acyl-[acyl-carrier- a (2E)-but-2-enoyl-[acp] UDP-3-O-acyl-N- a [prolipoprotein]-L-cysteine deazaguanosine L-cysteine succinylglutamate + + Fe multidrug 5-phosphate 5-aminovalerate ADP-L-glycero-β- α-Kdo-(2->4)- a 6-sulfo-α- 2498 2552 H PntAB H appA creatine cysteamine YnfB 5-phosphate 1-carboxyvinyltransferase: mrcA arnA isochorismate a (2E)-dec- glutamate- putrescine ketobutyrate a purine base (S)-3-hydroxy-(11Z) a cytidine uridine a 6,7- a 2,3,4-saturated decanoate decanoate protein]--UDP-N- acetylglucosamine in tRNA 3-oxohexanoyl-CoA desulfidase: semialdehyde nitric oxide a reduced maltohexaose maltopentaose a uracil in DNA H O octanoate gln lipid A-core oliosaccharide efflux pump isomerase: murA isomerase: a 1-acyl-sn-glycerol 3-phosphate a 1-acyl-sn-glycerol 3-phosphate transaminase: gabT D-manno-heptose α-Kdo-(2->6)- a tRNA precursor D-quinovosyl asp53 asp59 2 2 DsbA Tap a protein UDP-β-L-threo- crotonyl-[acyl- phosphatidylglycerol--prolipoprotein 34 putrescine aminotransferase: (2Z)-2-aminobut- CoA ligase: kbl lesion in DNA ATP -octadecenoyl-CoA in 23S rRNA in 23S rRNA dihydropteridine PhoB-P NarL-P fatty acid a 1,2-diacyl-sn-glycerol chenodeoxycholate chenodeoxycholate acetylglucosamine O- peptidoglycan 2-enoyl-[acp] deacetylase: lpxC tRNA preQ S- acetaldehyde L-2-amino-3- cyuA dehydrogenase: CTP flavorubredoxin phosphoethanolamine (KdoII) pyruvate AcrAB-TolC gutQ UDP-N-acetyl-α- gutQ 1 gly 5-aminovalerate lipid IV (E. coli) diacylglycerol 3-hydroxyacyl-CoA 23S rRNA 2'-O 23S rRNA 2'-O dihydropteridine GDP + pentapyranos- isochorismatase: carrier-protein] diacylglyceryl transferase: lgt 3-ketoacyl-CoA ligase: puuA patA 2-enoate A octanoul-ACP protein acyl-ACP protein- H [+ 3 more] [+ 3 more] acyltransferase: lpxA glycosyltransferase: trans-2- UDP-3-O-(3- adenosylmethionine oxobutanoate L-cysteine astD a drug Bcr a drug phosphate YhiD D-glucosamine- entB D-arabinose thiolase: fadA aminotransferase: puuE maltodextrin maltodextrin dehydrogenase: -ribose C2498 -ribose U2552 reductase: hmp protein- protein synthetase: synthetase: D-arabinose mrcB 4-ulose reductase: fabI hydroxymyristoyl) acetaldehyde 2 DNA- uracil-DNA hydrogen:oxygen thiol:ubiquinone glutamine decenoyl- acyl-CoA:1-acyl-sn- acyl-[acp]:1-acyl-sn- a [prolipoprotein]-S-1,2- ribosyltransferase- desulfhydrase: N - ADP-heptose:Kdo nitric oxide fadJ methyltransferase: methyltransferase: dihydropteridine phosphoaspartate phosphoaspartate UDP-3-O-[(3R)-3- 5-phosphate enolpyruvate UDP-4-amino-4- 5-phosphate α γ-glutamyl- 2 phosphorylase: phosphorylase: aas oxidoreductase aas glutaminase: peptidoglycan (2S,3S)-2,3-dihydroxy- ACP - -D-glucosamine glycerol-3-phosphate 2- glycerol-3-phosphate 2- diacyl-sn-glyceryl-L-cysteine isomerase: queA acetyl-CoA C- 4-aminobutanal dehydrogenase glutarate semialdehyde tnaA succinylglutamate formamidopyrimidine -lipid IV - CCA tRNA reductase: sulfoquinovosidase: glycosylase: oxidoreductase: [EntB aryl- a butanoyl-[acp] A rlmM rlmE reductase: nfsB phosphatase: phoR phosphatase: narX deoxycholate deoxycholate hydroxymyristoyl]- isomerase: UDP-N- deoxy-L-arabinose isomerase: UDP-3-O-(3- acyltransferase: L-putrescine (acetylating) glycosylase: mutM malP malP ung 3-hydroxyacyl-CoA a 2-O- a 2'-O- hyaC hyaB hyaA DsbB: dsbB a 2,3,4-saturated cheB YbhC glycosyltransferase: carrier protein] 2,3-dihydrobenzoate isomerase: O-acyltransferase: plsC O-acyltransferase: plsC an epoxyqueuosine 34 heptosyltransferase: nucleotidyltransferase: cca norV yihQ a 5,6,7,8- tetraphenylphosphonium tetraphenylphosphonium lipid A-core oligosaccharide di-trans,octa-cis lipid A-core D-myo- α glutarate-semialdehyde L-cysteine dehydrogenase: 2498 2552 an octanoyl-[acp] glu an L-1- a 1-acyl-sn-glycero- D-ribose 5- N-acetyl- -D- kdsD acetylenolpyruvoylglucosamine pbpC aminotransferase: kdsD hydroxymyristoyl) fadI γ-glutamylputrescine 2-iminobutanoate : mhpF methylcytidine methyluridine PhoB NarL DsbA fatty acyl-[acp] Tap a peptide MdtK glycerol 2- YncD 2,3-dihydro-2,3- β fabA prolipoprotein signal succinylglutamate waaC tetrahydropteridine oxidized norfloxacin norfloxacin (E. coli K-12 core type) -undecaprenyl oligosaccharide (E. inositol (2,5) reductase: murB phosphopantetheinyl -ketohexanoyl- aldehydo-D-arabinose in tRNA aminoacetone dehydrogenase: gabD desulfhydrase: α α fadB phosphatidylethanolamine 3-phosphocholine phosphate phosphate YdbD glucosamine aldehydo-D- arnB dihydroxybenzoate glucosamine N- oxidase: puuB acetaldehyde a [DNA]- -D- -D- a DNA containing in 23S rRNA in 23S rRNA peptidoglycan [acp] synthase: fabB peptidase: lspA butanoyl-CoA cysM desuccinylase: astE a 5'-phospho- a modified a tRNA 6-sulfo-α-D- maltopentaose maltotetraose uracil 3-oxo-(11Z)- a drug a drug diphosphate coli K-12 core type) bisphosphateD-myo-inositol ribose 5- glycerol-2- UDP-3-O-acyl-N- arabinose 5- ala UDP-N-acetyl- UDP-4-amino- transferase: entD a (3Z)-dec- 5-phosphate acyltransferase: epoxyqueuosine 4-(γ-L- glutarate-semialdehyde nucleotide- 4-oxo-2-pentenal heptosyl- nitrous oxide an oxidized glucopyranose glucopyranose an apurinic/ H O α glycosyltransferase: β dehydrogenase: entA β dehydrogenase: [DNA] nucleobase a 1,2-diglyceride quinovose octadecenoyl-CoA 2 2-nitroimidazole 2-nitroimidazole phosphate acetylglucosamine phosphate -D-muramate 4-deoxy- -L- holo-[acyl- -ketoacyl-ACP 3-enoyl-[acp] lpxD reductase: queG 1-pyrroline dehydrogenase: sad L-cysteine ADP Kdo -lipid IV containing a flavorubredoxin 1-phosphate 1-phosphate NimT (2,5) bisphosphate phosphate an (S-diacyl-sn-glyceryl)-L- acyl-CoA glutamylamino) adhE 3'-phosphate 2 A apyrimidinic site lysophospholipase: phosphatase: deacetylase: lpxC glu mtgA arabinopyranose synthase: fabF a lipoprotein signal peptide desulfhydrase: succinate 3' CCA end a drug a drug phosphohydrolase: phosphatase: carrier- 2,3-dihydroxybenzoate β-keto-cis-∆ 5 UDP-2-N,3-O-bis[(3R)- a queuosine 34 butanal glu RhsB UDP-3-O-(3- UDP-N- peptidoglycan UDP-4-amino-4- cysteinyl-[apolipoprotein] dehydrogenase: 2-oxobutanoate acetaldehyde glutarate tesA phoA YeiB protein] 3-hydroxytetradecanoyl]- a 1,2-diacyl-sn-glycerol 3-phosphate γ γ cysK appA phoA glutamate ser a 3-oxohexanoyl-[acp] -dodecenoyl- in tRNA fadE -glutamyl- - dehydrogenase: methylglyoxal HtrE hydroxymyristoyl) acetylmuramate--L- glycosyltransferase: deoxy-L-arabinose 2,3- D-arabinofuranose α apolipoprotein N- lipoprotein 2+ 2+ aldehydo-D-ribose glycerol synthase: [acp] -D-glucosamine aminobutyraldehyde L-cysteine L-glutamine glucosyl-(heptosyl) - UDP-α-D-glucuronate an adenine 37 a 2-oxo a single- a double a guanosine 18 a cytidine 34 2-oxepin-2(3H)- a siderophore- Mn MntP Mn Ins(2)P α D-arabinofuranose racemase: eutE 3 a [protein] (L-serine/L- long chain - -D-glucosamine alanine ligase: murC mrdB formyltransferase: dihydroxybenzoate- 5-phosphate acyltransferase: lnt signal peptide α-D-glucose 6-phosphate RNA an acetyl ester maltose D-alanyl-D-alanine Ins(1)P gln lipid A-core oligosaccharide acpS synthase: UDP-2,3- CTP:phosphatidate crotonyl-CoA dehydrogenase: puuC aminobutyraldehyde 2-ketobutyrate acetohydroxybutanoate glutarate desulfhydrase: degradation I Kdo -lipid A-phosphate in tRNA carboxylate met stranded RNA stranded DNA in tRNA in tRNA ylideneacetyl-CoA CheY-P asp bound Fe(III) Tsr a protein sn-glycero-3- 5-phosphate murI enterobactin 2 threonine) phosphate polyphosphate phosphoethanolamine (hep I) a 1,2-diacyl-sn-glycerol a carboxylate UDP-3-O-(3- peptidoglycan arnA [aryl-carrier 3-oxoacyl-[ACP] 3-deoxy- cytidyltransferase: cdsA peptidase: rseP 4-(γ-L- malY sugar phosphatase: ybiV recombination- tRNA (cytidine- maltose O- oxepin-CoA D-alanyl- di-trans,octa-cis- lipid A-core 1- UDP-4-deoxy-4- holo-[acyl synthase: fabB diacylglucosamine an N-acyl-(S-diacyl-sn-glyceryl) dehydrogenase: puuC formate- synthase: ilvG ilvM acetyl-CoA dioxygenase: glaH protein-serine/threonine tRNA (Gm18) 2'-O- inositol- protein- phosphocholine hydroxymyristoyl) 3-deoxy- UDP-N-acetyl- glycosyltransferase: protein] ligase: entE reductase: fabG D-manno- signal peptide enoyl-CoA D-alanine diphosphate diphosphatase: lpxH glutamylamino) γ sugar phosphatase: hxpA promoting 2'-O)-ribose acetyltransferase: hydrolase protein polyphosphate + + undecaprenyl phosphate Lit α formamido-β-L- carrier entB entD a (5Z)-3- -L-cysteinyl-[lipoprotein] -aminobutyraldehyde lyase: pflB L-cysteine gln 2 phosphatase: pphC methyltransferase: phosphate glutamine Li Li glucosamine N- D-manno- -D-muramoyl- D-glt ftsW [EntF L-seryl- octulosonate a CDP-diacylglycerol peptidase: sppA hydratase: fadJ acetohydroxybutanoate UDP- tRNA m A37 methionine acetylesterase: aes polynucleotide ferric-chelate dipeptidase: NhaA enterobactin butanoate sugar phosphatase: yidA endoribonuclease nuclease: rpnA methyltransferase: maa [multifunctional]: phosphoaspartate kinase: ppk + + Blc L-alanine arabinopyranose protein] entF entE oxododec- lipoprotein dehydrogenase: patD 2-ketobutyrate synthase: ilvI ilvH (S)-2-hydroxyglutarate succinate desulfhydrase: glutaminase: asnB glucuronate:LPS(HepIII) methyltransferase: protein-serine/threonine phosphorylase: trmH reductase: phosphatase: glutaminase: Na Na acyltransferase: octulosonate a nascent peptidoglycan carrier protein] a (3R)-3-hydroxyhexanoyl-[acp] 8-phosphate lipid X enoyl-CoA L-serine transaminase: toxin ChpB: chpB carboxylesterase: bioH a 2'-O- trmL 6-O-acetyl-α-D- paaZ phosphatase: cheZ ddpX EnvY synthase: synthase: 5-enoyl-[acp] release complex: formate- metC glutaminase: glsA phosphosugar phosphatase: pphB DNA a 2'-O- 3-oxo-5,6- suhB cheB lpxD 8-phosphate undecaprenyl- L-serine-- γ γ 2-aminoprop- glycosyltransferase: waaH rlmN pnp 18 nfeF long chain α a 1-palmitoyl-2- with (L-alanyl-γ-D-glutamyl- entB entD ∆ 5 synthase: kdsA a peptide hydratase: fadB -glutamyl- - degradation ybdL carboxylesterase: yjfP methylguanosine glucopyranosyl- lipid A-core oligosaccharide an L-1- -D-Kdo-(2->4) UDP-N- phosphopantetheinyl 3-oxo-cis- - lipid A phosphatidylserine lolE lolD lolC phosphatase: yigL endonuclease: 34 myo-inositol glu UDP-2-N,3-O-bis[(3R)- phosphate acpT [holo EntF] CDP-diacylglycerol--glycerol- lyase: tdcE (S)-2-aceto-2- L-2-hydroxyglutarate glutaminase: glsB protein-serine/threonine methylcytidine didehydrosuberyl- CheY D-ala Tsr a peptide + + α acyl-sn-glycero-3- (S)-5-hydroxyisourate DHAP a primary amine synthase: kdsA meso-2,6-diaminopimeloyl-D- (3R)-3- aminobutyrate 2-enoate (1->4)-D-glucose polyphosphate Na NhaB Na (E. coli K-12 core type) phosphatidylethanolamine - -D-Kdo-(2->6) O-phospho-L-serine acetylmuramoyl- entF entE transferase: entD dodecenoyl- disaccharide synthase: pssA hydroxybutanoate dehydrogenase: lhgD phosphosugar an [RNA]-3'- a 5'-hydroxy- ralR in tRNA in tRNA CoA YggT 3-hydroxytetradecanoyl]- 4-deoxy-4- ligase: entF hydroxyhexanoyl- KDO-8P 3-phosphate 3- (S)-3-hydroxybutanoyl-CoA hydrolase: puuD imidazole glycerol glucosyl-(heptosyl) - a 2- phosphatase: pphA -lipid A (E. coli) phosphocholine glycerone primary alanyl-D-alanine) pentapeptide a holo-[EntB aryl- [acp] 3 UDP 4-(methylsulfanyl) a single- 2+ 3-phospho-L-serine α L-alanine--D- (2,3-dihydroxybenzoyl) synthase: lpxB a LolA-lipoprotein complex ser 5'-deoxyadenosine 37 phosphatase: phoA a proteinogenic ribonucleoside- ribonucleotide- a nucleoside a 5'-phosphooligonucleotide Fe a siderophore -D-glucosamine KDO-8P formamido- [acyl-carrier protein] phosphatidyltransferase: (R)-2,3-dihydroxy-3- phosphate glucosyluronate-Kdo met methyladenine a [protein] Ser/Thr acetate an alcohol 5-hydroxyisourate phosphate amine carrier protein] a holo-[EntF L- reductase: propanoyl-CoA 2 -2-oxobutanoate stranded RNA phosphatase: phoA UDP-2,3- glutamate L-arabinose adenylate (L-seryl)adenylate lipid A disaccharide pgsA 3-hydroxyacyl-CoA + serine 2-oxoglutarate proline degradation synthase: hisH hisF α-D-glucopyranose amino acid 3'-phosphate 3'-[RNA] diphosphate Ni(2+) ABC hydrolase: hiuH BhsA peptidoglycan DD- peptidoglycan DD- dehydratase: fabZ 3-deoxy- a 3-sn-phosphatidyl-L-serine methylpentanoate:NADP -lipid A-phosphate in tRNA 2+ 2+ Lipid A phosphatase: oxidase: multidrug ligase: murD seryl-carrier protein] fabG (E. coli) dehydrogenase: Ni Ni 3-phosphoserine deoxycholate deoxycholate diacylglucosamine 3-deoxy- transferase: oxidoreductase deaminase: transporter (S)-2-oxo-4- phoA tynA efflux pump carboxypeptidase: transpeptidase: mrcA a (3R,5Z)-3- D-manno- fadB phosphate 2-iminopropanoate xanthosine-5'- palmitoyltransferase: phosphatase: aphA novobiocin novobiocin YbjN diphosphatase: lpxH arnC 2,3- a (2E)-hex-2-enoyl-[acp] tetraacyldisaccharide 1-(3-sn-phosphatidyl)- phosphatidylserine (isomerizing): ilvC tdcG hydroxy-4-carboxy- MdtABC- D-manno- mrcA peptidoglycan DD- a mature peptidoglycan with hydroxydodec- octulosonate propionyltransferase: pta pro phosphate:L- pagP dihydroxyacetone an aldehyde dodecyl sulfate dodecyl sulfate UDP-N-acetyl- 4-deoxy-4- dihydroxybenzoate- enterobactin 4'-kinase: lpxK 3-hydroxyacyl-CoA an aminated amino 3-hydroxybenzoyl- 3-(N-morpholino) 2-dehydro-3-deoxy- a guanine 46 2-dehydro-3- 1-myristoyl- ser octulosonate meso- transpeptidase: mrcB (L-alanyl-γ-D-glutamyl-meso- 8-phosphate sn-glycerol 3-phosphate decarboxylase: psd an N-acyl-(S-diacyl-sn-glyceryl) Degradation/ (R)-2,3-dihydroxy- L-serine D-serine glutamine amido- a uridine 47 in tRNA Phe 2-oxobutanoate β pimeloyl-CoA H O (2E,6E)-farnesyl an acyl-[acyl- thiamine lipid A-core oligosaccharide 5-ureidoimidazoline TolC lipid X α-D-muramoyl-L- peptidoglycan DD- 5-enoyl-[acp] 4-aminobutanoate proline SAM -D-glucose 6-phosphate glycerophosphoserine ala 2 L-rhamnonate trans-aconitate his717 sn-glycerol syringaldazine gln diaminopimelate formamido-α-L- [aryl-carrier synthase: hexanoyl-[acyl- dehydrogenase: propanoyl deaminase: degradation group donor CoA propanesulfonate diphosphate protoheme in tRNA deoxy-D-gluconate ArcB-P a protein Trg GTP YafL a 1,2-diacyl-sn-glycerol 8-phosphate carboxypeptidase: peptidoglycan D,D- 2,6-diaminopimeloyl-D-alanyl- 3-hydroxy cis phosphatase: phosphatidylglycerophosphatase: -L-cysteinyl-[lipoprotein] Utilization/ 3-methylpentanoate ligase (AMP- carrier protein] diphosphate pyrophosphoethanolamine hepta-acylated Kdo alanyl-D-glutamate protein] ligase: entE entB entD carrier-protein] lipid IV (E. coli) fadJ phosphate dehydrogenase: sugar phosphatase: ybiV 7 2-keto-3-deoxy- 3-phosphate a 2-acyl-sn-glycero- 2 arabinopyranosyl ∆ 5 A an L-1-phosphatidylethanolamine 4-aminobutyrate sdaA L-aspartate trans-aconitate 2- tRNA m G46 acyl-CoA:1-acyl- polyphenol protein- UidC lipid A phosphatase: mrcB transpeptidase: ftsI D-alanine) pentapeptide -dodecenoyl- kdsC pgpC Assimilation - Other 2,3-dihydroxy-3- forming): guaA phosphate thiamin alanyl lipid A (E. coli) ditrans,octacis entF entE reductase: fabI degradation II (aerobic) pyruvate (S)-1-pyrroline-putA sugar phosphatase: hxpA 2-keto-3-deoxy- methyltransferase: methyltransferase: D-gluconate sn-glycerol-3- oxidase: glutamine 3-phosphocholine YhhS disaccharide kdsC enterobactin aminotransferase: propionate methylvalerate serine D-serine 2-oxobutanoate 3-hydroxybenzoyl- alkanesulfonate phosphohistidine pyrophosphate guanylate lipopolysaccharide UDP-N- D-alanyl-D-alanine peptidoglycan DD- [acp] 3-deoxy- phosphatidylglycerophosphatase: acetoacetate acetoacetyl-CoA [+ 3 isozymes] tRNA 3-amino-3- sugar phosphatase: yidA glycerophosphoserine 8-amino-7- heme O dehydrogenase: acyltransferase: aminopeptidase: a lipopolysaccharide a lipopolysaccharide synthase: lpxB -undecaprenyl synthase: L-serine-- α-Kdo puuE kinase: ackA deaminase: 5-carboxylate aminotransferase: CoA monooxygenase: L-rhamnonate tam trmB phosphatase: sixA phosphate 2-O- hydrolase: nudJ pgeF glutaminase: transport system acetylmuramoyl- carboxypeptidase: transpeptidase: mrdA a hexanoyl-[acp] dehydratase: D-manno- pgpB degradation hydro-lyase: ilvD D-serine glu phosphodiesterase: ugpQ oxononanoate synthase: (E)-3- an N 7 - kduD plsX pepN tetramethoxy cyclase α-Kdo D-ala phosphate entB entD [holo EntF] carboxypropyltransferase: phosphosugar aldolase: yfaU acyltransferase: cheB lipid A undecaprenyl acetyl-CoA 4-aminobutyrate tdcB asp avtA thioesterase: entH ssuD 46 thiamine palmitoleoyl-[acp] a partially deacetylated poly-β- a ribonucleoside L-alanyl-D- dacA fabZ 3-deoxy-manno octulosonic phosphatidylglycerophosphatase: periplasmic disulfide bond reduction (to acetyl CoA) propionate (3S)-3-methyl-2- ammonia- tapT synthase: bioF cyoE (methoxycarbonyl) methylguanine 3-deoxy-D-glycero- azobismethylene SetC D-glucopyranose D-gluconate phosphate- entF entE ligase: entF acetyltransferase: phosphatase: yigL an acyl phosphate 1,2-dimyristoyl-plsC a peptide glu cyclic-GMP thioesterase: tesA O-phosphoethanolamine disaccharide 3-deoxy-manno glutamate--2,6- a nascent peptidoglycan β-ketooctanoyl- acid transaminase: kinase: tdcD oxopentanoate L-serine lyase: L-aspartate:fumarate 2,5-hexodiulosonate ArcB phosphate Trg 1,6-N-acetyl-D-glucosamine I 2',3'-cyclic 6-phosphate 6-phosphate D-alanine--D- D-alanyl-D-alanine α a (2E,5Z)-dodeca- -octulosonate pgpA acetoacetate pent-2-enedioate in tRNA quinine a palmitoleoyl-[acp] palmitoleate an ion an ion UbiB (E. coli) -octulosonate -L-ara4FN transferase: two reduced atoB gabT deaminase: dsdA a 3-[(3S)-3-amino- phosphosugar sn-glycerol phosphate phosphoryl- glucose-6- gluconate 6- diaminopimelate carboxypeptidase: with D,D cross-links (meso- a 2,3-dihydroxybenzoyl- [acp] synthase: fabB 3,5-dienoyl-[acp] cytidylyltransferase: a reduced an [oxidized isoleucine 2-aminoprop- antiport: dcuA a deaminated sn-glycerol (8S)-8-amino-7- 3-(N-morpholino) (S)-lactaldehyde pyruvate an organosulfur compound an organosulfur compound NfrA alanine deformylase: an L-1-phosphatidyl-sn-glycerol cysteine residues acetate CoA- propanoate L-glutamate-5- 3-carboxypropyl]- S-methyl-5'-thioadenosine (S)-2- phosphatase: phoA ser coenzyme A 3-hydroxybenzoate sulfite 3-phosphate 2',3'-cyclic-nucleotide ethanolamine phosphate phosphate PhoE tetraacyldisaccharide cytidylyltransferase: ligase: murE diaminopimelate containing) a seryl-[EntF L- β-ketoacyl-ACP kdsB waaA thioredoxin 1 DsbD protein] succinate transaminase: 2-aminoprop-sdaB 2-enoate asp amino group donor 3-phosphate oxononanoate propanal ferroheme o endo-poly-β-1,6- ligase: ddlB dacD [EntB aryl- 5 transferase: ydiF acetyl-CoA semialdehyde 47 Phe aminobutanoate β nitrite nitrite 2'-phosphodiesterase: a short-chain carboxylate a short-chain carboxylate 4'-kinase: lpxK kdsB 4-amino-4-arnD seryl-carrier protein] cis-∆ -dodecenoyl- in a protein uridine in tRNA -D-glucopyranose phosphatase: phosphatase: phosphatase: carrier protein] synthase: fabF α-Kdo-(2->6)- semialdehyde ilvE 2-enoate D-glucosamine [+ 27 more] [+ 27 more] D-alanine--D- D-alanyl-D-alanine deoxy-α-L- [acp]:NAD+ CMP-Kdo acetoacetyl-CoA L-glutamate γ- NarK cis-vaccenoyl-[acp] cpdB phoA phoA phoA UDP-N-acetyl- lipid IV (E. coli) cardiolipin synthase: clsB hydrolase: pgaB lipid IV (E. coli) CMP-Kdo alanine carboxypeptidase: A cardiolipin synthase: clsC transferase: succinate- aspartate ammonia- thioesterase: tesA a ribonucleoside YciB A α arabinopyranosyl oxidoreductase: semialdehyde nitrate nitrate D-glucopyranose D-gluconate -D-muramoyl- a mature peptidoglycan 2,3-dihydroxybenzoyl- a 3-oxooctanoyl-[acp] succinate ile 1-palmitoyl- nitrite NarK nitrite a cis-vaccenoyl-[acp] cis-vaccenate ethanolamine an ion an ion ligase: ddlA dacC fabI cardiolipin synthase: clsA atoA atoD semialdehyde lyase: aspA a cytosine 32 an [L-cysteine iron(III)-enterobactin 3,4-dihydroxyphenylacetyl- hydrogen 2-deoxy-2,3- a guanine 37 (S)-2- a phosphorylated 3'-phosphate L-alanyl-γ-D- ditrans,octacis α-D-Kdo-(2->4) dehydrogenase: + enterobactin a protein a nucleoside a signal peptide with D,D cross-links (meso- [EntB]:seryl-[EntF] 2,3- acetoacetyl-CoA dehydrogenase semialdehyde glycine cleavage 2-iminopropanoate L-cysteine degradation III a uridine in tRNA SAM desulfurase]-S- A(H2) nitrite L-carnitine NAD dehydro-N- hydroxypyruvate isocitrate sn-glycerol D-serine a partially deacetylated a partially deacetylated an organosulfur compound an organosulfur compound YiaD glutamyl-meso-2,6- [+ 3 isozymes] -undecaprenyl -α-D-Kdo-(2->6) putA in tRNA complex CoA peroxide dITP in tRNA hydroxyglutarate diphosphate OmpC 3-deoxy- D-alanyl-D-alanine diaminopimelate containing) dihydroxybenzoate 3-oxoacyl-[ACP] a (5Z)-dodec- cyclopropane + dehydrogenase ammonium hydroxypyruvate 3-phosphate aggregate signal nitrite nitrite poly-β-1,6-N-acetyl-D- poly-β-1,6-N-acetyl-D- a short-chain carboxylate a short-chain carboxylate (NAD ): puuC 2-iminopropanoate sulfanyl-L-cysteine acetylneuraminate tRNA m 1 G37 2-oxoglutarate dehydrogenaseisocitrate acyl-CoA:1-acyl- D-manno- diaminopimelate phosphate -lipid A (E. coli) reductase: fabG 5-enoyl-[acp] fatty acid (CFA) acetyl-CoA (NADP + ): gabD a [glycine- deoxyinosine triphosphate 2-deoxy-2,3- protein nucleoside D-serine a nascent peptidoglycan transferase: entF Ptd Gro L-alanine degradation I glu reductase ((S)-2- reductase: ghrA enterochelin peptide NarU glucosamine (fragment 1) glucosamine (fragment 2) [+ 27 more] [+ 27 more] YddA 2 succinate cleavage complex ferric nitrite reductase - carnitine dehydro-N- methyltransferase: dehydrogenase sn-glycerol-3- diphosphate ammonia- octulosonic with (L-alanyl-γ-D-glutamyl- ∆ KDO biosynthesis thiol- acetyltransferase: glutamine cys tRNA 3-amino-3- tRNA cytosine 32 2- hydroxyphenylacetyl- hydroperoxidase: pyrophosphatase: rdgB hydroxyglutarate- esterase: fes disaggregase: peptidase: lipid IV 4-amino-4-deoxy- 3-oxo-cis- 7- semialdehyde 6 trmD hydroxypyruvate phosphatase: phosphate 2-O- nitrate nitrate acid D-alanyl- A a [phospholipid] cis disulfide H protein] N -[(R enterobactin NADH dependent: monooxygenase: acetylneuraminate kinase: ndk lyase: nitrite NirC nitrite meso-2,6-diaminopimeloyl- an N-(2,3- a (3R)-3-hydroxyoctanoyl-[acp] transferase: atoB glycine synthetase: glnA carboxypropyltransferase: sulfurtransferase: CoA thioesterase: paaI katG nucleoside triphosphate an N 1 - forming): serA reductase: ghrB N-(2,3- clpB rseP di-trans,octa-cis an ion an ion D-alanine- L-arabinosyltransferase: tetradecenoyl- dehydrogenase )-lipoyl]-L-lysine esterase: fes nirD nirB yeaX yeaW hydratase: nanY aceK acyltransferase: dsdA a 2-acyl-1-lyso- guanosine D-glucosamine D-glucose 6- transferase: dihydroxybenzoyl)- waaA -olefinic fatty acid exchange: decarboxylase: ala pyruvate cysteine L-glutamate tapT ttcA pyrophosphohydrolase: α 37 an unfolded a nucleoside a nucleoside 5'- an organosulfur compound an organosulfur compound D-alanine) tetrapeptide [acp] cyclopropane (NAD + ): sad N-acetyl- - methylguanine 2-oxoglutarate D-glycerate an isocitrate plsC dihydroxybenzoyl) -undecaprenyl 2',3'-cyclic 6-phosphate phosphate waaA adding arnT dsbD acetyl-CoA alanine racemase: dadX pyruvate 1-palmitoyl- triphosphate a peptide pyruvate phosphatidylethanolamine monophosphate OmpF OsmB seryl-[EntF L-seryl- (3R)-3- fatty acyl H-Gcv-protein- gcvP gln transaminase: aspC degradation IX (via mazG neuraminate in tRNA dehydrogenase -L-serine protein diphosphate a short-chain carboxylate a short-chain carboxylate enzyme: synthase: fabB alanine racemase: alr (3,4- 2-myristoyl undecaprenyl monophosphate glucosamine glucose-6- YjiK L,D- L,D- L,D- α α carrier protein] hydroxyoctanoyl- a (7Z)-3- thioredoxin:disulfide (dihydrolipoyl) 4-aminobutanoate) S-methyl-5'- a 3-[(3S)-3-amino- 32 an [L-cysteine iron(III)-[N-(2,3- N-(2,3- L-malic ADP-D-ribose FtsK guanosine 2',3'-cyclic nucleoside [+ 27 more] [+ 27 more] α 4'- -L-Ara4N- - phospholipid succinate a 2-thiocytosine coenzyme A A H O + dIMP nicotinamide pyrophosphate 6-phosphate phosphate -Kdo-(2->6)- murF lysine:NAD+ alanine racemase: metC 2-oxo-3-sulfanylpropanoate 3-carboxypropyl]- dihydroxybenzoyl) dihydroxybenzoyl) dihydroxyphenyl) 2 ammonium NAD H O trimethylamine phosphatidate 2-acyl- monophosphate transpeptidase: ldtD carboxypeptidase: transpeptidase: ldtD Kdo-(2->4)-α- enterobactin [acyl-carrier protein] oxotetradec- a [phospholipid]synthase: cfa oxidoreductase: trxA thioadenosine in tRNA desulfurase]- 2 semialdehyde phosphatase: phosphodiesterase: phosphatase: phosphatase: lipid IV (E. coli) oxidoreductase: lpd alanine racemase: malY glu uridine in tRNA -L-serine] complex -L-serine acetate lysophospholipase: phosphatase: aphA A ldtD a mature peptidoglycan synthase: entF dehydratase: fabZ 7-enoyl-[acp] L-cysteine di-trans,octa-cis cpdB UDP-N-acetyl- Kdo-(2->6)-[P4'- α-Kdo-(2->4)-α-Kdo- fatty acid containing a [glycine- pgpB phoA phoA KDO a nascent peptidoglycan a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl- ∆ 7 a [glycine-cleavage D-ala glutamate pldA α α-L-ara4N]-lipid A 3-oxo-cis- - cyclopropane cleavage complex 3-mercaptopyruvate:cyanide -undecaprenyl a nucleoside D-glucosamine D-glucose transferase: -D-muramoyl- with L,D cross links (meso- with (L-alanyl-γ-D-glutamyl- a (2E)-oct-2-enoyl-[acp] (2->6)-lipid IV (E. coli) 6 3'-GMP CreD a nascent peptidoglycan with meso-2,6-diaminopimeloyl- enterobactin tetradecenoyl- A thiol- complex H protein] N - decarboxylase γ H protein] N 6 - sulfurtransferase: sseA an [HPr]- phosphoenol RNase R degradation a [DNA]-nucleotide-3'- a guanine 527 37 (R)-2- 1-palmitoyl- an organic an adenosine 34 1-deoxy- phosphate YqhH waaA L-alanyl- -D- diaminopimelate containing) (L-alanyl-γ-D-glutamyl-meso- meso-2,6-diaminopimeloyl- lauroyl disulfide aminomethyldihydrolipoyl- D-alanine:quinone B: gadB cob(II)inamide ATP a DNA containing an choline γ-butyrobetaine isethionate adenine riboflavin geranyl glyoxal YgfS D-alanine) tetrapeptide [acp] hydroxylamine val sn-glycerol Arg2 D-xylulose α glutamyl-meso-2,6- octanoyl-[acyl- dihydrolipoyl- L-histidine pyruvate apurinic/apyrimidinic site substrate RNA phosphoglycolaldehyde in 16S rRNA in tRNA hydroxyglutarate DsbA hydroperoxide in [tRNA ] sn-glycero-3- -Kdo-(2->4)- 2,6-diaminopimelate) tripeptide glycine) tetrapeptide reductase: fabG acyltransferase: exchange: Alcohol Degradation L-lysine oxidoreductase glutamate 1 diphosphate 1-deoxy- a carboxylate 7 6 2-oxoglutarate flavin 3-phosphate alkyl tRNA glyoxalase phosphoethanolamine α diaminopimeloyl- carrier-protein] L-lysine (deaminating): dadA 16S rRNA m G527 tRNA m A37 protein acyl-CoA:1-acyl- geranyl -Kdo-(2->6)- a (3R,7Z)-3- lpxL dsbD hydrogen sulfide pyruvate decarboxylase 34 D-xylulose methyltransferase: reductase ((R)-2- reductase: cysJ sn-glycerol-3- hydroperoxide diphosphate adenosine III: elbB lipid IV (E. coli) D-alanyl-D-alanine reductase: fabI hydroxytetradec- α-Kdo-(2->4)-α- an oxidized a [reduced an intra- cobinamide phosphoenol apurinic/apyrimidinic choline γ-butyrobetaine isethionate methyltransferase: thiol:menaquinone YaaJ A phospho-N- a mature peptidoglycan superpathway of glycol A: gadA 3'-phosphodiesterase: hydroxylamine hydroxyglutarate- riboflavin reductase: deaminase: kinase: glyoxalase thioredoxin 1 DsbD protein] protein disulfide glycerol degradation V pyruvate RNase R: rnr rsmG yfiC oxidoreductase phosphate 2-O- phosphatase: 7-enoyl-[acp] Kdo-(2->6)-(lauroyl) ethanol degradation I 4-aminobutanoate adenosyltransferase: pyruvate:protein endonuclease: xthA monooxygenase: monooxygenase: monooxygenase: 7 6 xylB a 1-acyl-2-lyso- adenosine α-D-mannose acetylmuramoyl- with L,D cross-links (meso- a mature peptidoglycan with a mature peptidoglycan an octanoyl-[acp] metabolism and degradation aminomethyltransferase: nfo reductase: hcp an N - an N - forming): serA reductase: fre ahpC ahpF nudI tadA III: yajL YbiT a phosphate ∆ 7 DsbB: dsbB acyltransferase: 34 1-deoxy-D- FMN YddL pentapeptide- diaminopimelate containing) γ γ 3-hydroxy cis -lipid IV (E. coli) btuR phosphotransferase: ptsI endonuclease IV: nfo yeaX yeaW yeaX yeaW ssuD 527 37 an inosine phosphatidylethanolamine 2',3'-cyclic 1-phosphate (L-alanyl- -D-glutamyl-meso- with (L-alanyl- -D-glutamyl- A gcvT methylguanine methyladenine 2-oxoglutarate reduced riboflavin an alcohol geranyl glycolate GMP monoester 1-palmitoyl-2-plsC Arg2 xylulose 5- lauroyl transferase: mraY -tetradecenoyl- myristoyl-acyl glycerol val DsbA in [tRNA ] monophosphate mannose 1- undecaprenyldiphospho- 2,6-diaminopimelate) tripeptide meso-2,6-diaminopimeloyl- β-ketodecanoyl- ethylene glycol ethanol in 16S rRNA in tRNA oxidized monophosphate nucleoside 5'- acid phosphatase / FMN palmitoleoyl [acp] carrier protein- glycolaldehyde 1 cis-vaccenoyl phosphate adenosine 2',3'-cyclic phosphate OrtT acyltransferase: glycine) tetrapeptide [acp] synthase: fabB glycerol an [HPr protein]- a nucleoside 5'- a [DNA]-3'- succinate monophosphate phosphatase: N-acetylmuramoyl-L- ethanol π a diribonucleotide glycolaldehyde glycolaldehyde A ammonium H O 1-acyl- phosphotransferase: dehydratase: dependent adenosylcobinamide pyruvate a [DNA]-3'-hydroxyl a 5'-deoxyribose- phosphate trimethylamine trimethylamine sulfite 2 phosphatidate phosphodiesterase: phosphatase: lpxL acyltransferase: Respiration glycolaldehyde dehydrogenase: triphosphate N -phospho- monophosphate hydroxyl semialdehyde phosphatase: aphA phoA alanyl-γ-D-glutamyl-meso β-ketoacyl-ACP L-carnitine respiration dehydrogenase: adhP 5-phosphate-[DNA] lysophospholipase: cpdB aphA lpxP fabZ acyltransferase: reductase: fucO gldA L-histidine YbhL phoA -2,6-diaminopimeloyl- synthase: fabF ethanol guanosine pldA riboflavin a (2E,7Z)- lpxM dihydroxyacetone 3'-AMP an alcohol D-mannose ElfC D-alanyl-D-alanine α-D-Kdo-(2->4) L-carnitine dehydrogenase: adhE Secondary Metabolite Degradation α tetradeca-2,7- glycolaldehyde anhydromuropeptides recycling I β DinF -Kdo-(2->4) a 3-oxodecanoyl-[acp] α acetaldehyde dihydroxyacetone fructoselysine curcumin degradation a deaminated an N-acetyl- - 2251 966 L-glyceraldehyde D-galactosamine a HypE hydrogenase type-1 N-acetylglucosaminyl dienoyl-[acp] - -D-Kdo-(2->6) pyridoxamine + guanosine a guanine 7 d-biotin d sn-glycero-3- α 34 pyruvate glutathione bromoacetate glutathionylspermidine NAD(P)H H a quinone fumarate m GTP glu DNA with lesion - -Kdo-(2->6) 7 glycolaldehyde kinase: dhaK and psicoselysine a 5,10- gly a uridine D-hexosaminide asp 3-phosphate 6-phosphate maturation protein- Trg Ap4A D-cysteine transmembrane a carboxylate Kdo - transferase: murG cis-∆ - -lipid A (E. coli) GlcNAc-1,6- amino group donor 5'-phosphate in 23S rRNA in 16S rRNA -sulfoxide phosphoethanolamine 2 carnitine--CoA acetaldehyde -(lauroyl)-lipid 3-oxoacyl-[ACP] superpathway of fatty acid biosynthesis I (E. coli) dehydrogenase: dhaL dhaM degradation methylenetetrahydrofolate in tRNA 23S rRNA 2'-O 2 7 L-glyceraldehyde galactosamine- S-carboxamide Nucleotide proteins biotin (palmitoleoyl) lipid II (meso tetradecenoyl- ADP-heptose:Kdo -lipid anhMurNAc- curcumin 16S rRNA m G966 m GTP [HypE]-S- diadenosine D-cysteine IbsB IV (E. coli) 2 ligase: caiC dehydrogenase N 6 -(D-psicosyl) -ribose G2251 6-phosphate chemotaxis protein excision rhomboid sulfoxide A reductase: fabG aldA L-Ala-γ-D-Glu- β-N- pyrophosphatase: 3-phosphate carboxamide -lipid IV diaminopimelate [acp]:NAD+ A heptosyltransferase: NADPH-dependent pyridoxamine- bromoacetate quinone methyltransferase: methyltransferase: tetraphosphatase: desulfhydrase, protease: YhgE myristoyl-acyl A (acetylating): mhpF DHAP DAP-D-Ala -L-lysine pyruvate:ferredoxin glutathionylspermidine L-aspartate methyltransferase: reductase: gpr deaminase/ repair: uvrB reductase: D-glyceraldehyde ActS myristoyl-acyl containing) oxidoreductase: waaC acetyl-CoA curcumin 5-carboxymethylaminomethyluridine- dehalogenase: acetylglucosaminidase: reductase: rsmD yceF dehydratase: apaH PLP-dependent: β UMP a phosphate carrier protein- glycolate acetaldehyde oxidoreductase phosphate amidase: gss oxidase: rlmB an N 2 - N 7 - isomerase: agaS cheR uvrC uvrA glpG bisC AMP a lipopolysaccharide -D-Glc-PP-Und an aliphatic amine a (3R)-3-hydroxydecanoyl-[acp] fabI fructoselysine 3- reductase: curA tRNA synthase: mnmE mnmG nagZ 2-O- sn-glycerol hypE dcyD cleaved type-1 2+ 2+ 3-phosphate carrier protein- transaminase gstB nfsB 966 D-tagatofuranose a HypE hydrogenase DNA without Zn Zn AMP UMP phosphatase: phoA monoester dependent heptosyl-Kdo -lipid A dehydrogenase: adhE nadB 2251 methylguanine methylguanosine glu-Me ADP 2 1,6-anhydro-N- epimerase: frlC dihydrocurcumin biotin D-glyceraldehyde amine dependent glycolate superpathway of hexitol degradation (bacteria) methylguanosine 3-phosphate 6-phosphate maturation Trg pyruvate lesion transmembrane Cd 2+ FieF Cd 2+ phosphatase: 5'-ribonucleotidase: ushA alkaline acyltransferase: (3R)-3- a (7Z)-tetradec- acetyl-CoA (R)-carnitinyl-CoA acetaldehyde acetylmuramoyl- in 16S rRNA 5'-phosphate 3-phosphate crotonobetainyl- β in 23S rRNA proteins 2+ 2+ oxidase: acyltransferase: ADP-heptose--LPS dehydrogenase: 6 a reduced an N-acetyl- - protein-S-cyanate Fe Fe phoA nucleoside 5'- phosphatase: lpxM 7-enoyl-[acp] carboxyltransferase: N -(D-fructosyl) NADPH-dependent + an aminated amino S-(acet-2-yl) YaaY superpathway of aromatic amino acid biosynthesis Amino Acid Biosynthesis hydroxydecanoyl- γ-butyrobetainyl- CoA dehydrogenase: eutE L-alanine a 5-carboxymethylaminomethyluridine 34 acetyl-CoA CO H glutathione spermidine an alcohol + phosphatase: tynA α-D-Kdo-(2->4) lpxM superpathway of branched chain amino acid biosynthesis heptosyltransferase: acetyl-CoA:ACP glcD glcE glcF 2 ferredoxin [iron- PLP bromide D-hexosamine a quinol NAD(P) 2-iminosuccinate succinate monophosphate phoA L-proline L-histidine biosynthesis superpathway of L-asparagine biosynthesis superpathway of L-homoserine superpathway of L-serine L-selenocysteine biosynthesis I (bacteria) accA accD amidase: ampD D-sorbitol 6-phosphate -L-lysine dihydrocurcumin a 7,8-dihydrofolate group donor -glutathione 2+ 2+ phoA [acyl-carrier protein] 3-oxo-cis-∆9- transacylase: fabH CoA:carnitine hydratase: caiD in tRNA sulfur] cluster Mn Mn adenosine -α-D-Kdo-(2->6) (Kdo) -lipid biosynthesis I and L-methionine biosynthesis and glycine biosynthesis I waaF acetyl-CoA reductase: curA MntH phosphatase: aphA an aldehyde RlpA 2 D-erythrose dehydratase: fabZ hexadecenoyl- CoA glyoxylate Fe 2+ Fe 2+ D-glyceraldehyde an alcohol -lipid A (E. coli) A, cold adapted (from L-glutamate) (heptosyl) - N-acetyl-β-D- L-alanyl-γ-D- sorbitol-6- fructoselysine uridine 4-phosphate pyruvate [acp] 2 transferase: di-trans,octa-cis an α-D-glucosyl- thr PRPP sec malonyl-CoA 6-kinase: frlD tetrahydrocurcumin 3 asp 3-phospho-D-glycerate ser a tRNA a (2E)-dec-2-enoyl-[acp] Kdo -lipid A glucosamine-1,6- glutamyl-meso-2,6- phosphate 2- an N - an intrastrand non- 745 asp 2 a deoxyinosine a [DNA]-nucleotide- 2-dehydro-3- a guanine a cytidine D-erythro-7,8- an oxidized (2E,4Z)-deca- 2+ 2+ -undecaprenyl YchE 3-deoxy-7- synthase: fabB caiB γ-butyrobetainyl- crotonobetainyl- 6 an acyl-[acyl- NADPH NAD + citrate 2+ Co Co lipopolysaccharide glu acetolactate D-3-phosphoglycerate selenide lipopolysaccharide malonyl-ACP glyoxylate malate anhydro-N-acetyl- diaminopimeloyl- D-mannitol 1-phosphate dehydrogenase: N -(6-phospho- a 2-acyl-1-lyso- 2-oxoglutarate methylcytosine adjacent cyclobutane 32 Ins(2)P glu ppGpp L-kynurenine 3',5'-ADP Fe ATP a (9Z)-3- [acyl-carrier-protein] S 2-oxoglutarate decarboxylation to succinyl-CoA hν in DNA 3'-phosphoglycolate deoxy-D-gluconate thr in 23S rRNA in tRNA dihydroneopterin hybrid- Tap 2,4-dienoyl-CoA 2+ 2+ phosphate phosphoheptulonate threonine CoA CoA carrier protein] Cd Cd synthase: dehydrogenase: serA decanoyl-[acyl- core heptose an acetyl-[acp] decarboxylase: carboligase: synthase β-D-muramate D-alanine srlD D-fructosyl) phosphatidylethanolamine in DNA thymidine dimer in DNA aconitate 1 2,4-dienoyl- non-heme ZupT glutamate 5- phosphoribosyltransferase: aspartate oxohexadec- -malonyltransferase: 23S rRNA m G745 tRNA Cm32 cluster protein ppGpp 3'(2'),5'- 2+ 2+ synthase: aroF deaminase: L-aspartate:ammonia L-aspartate:L- selenide, L-serine:tRNASec gcl G: glcB glycerol and glycerophosphodiester degradation -L-lysine threonine dihydroneopterin inositol NADH chemotaxis protein kynurenine- Zn Zn kinase: proB ilvI ilvH hisG kinase: 3-phosphooxypyruvate carrier-protein] 9-enoyl-[acp] (I) kinase: waaP fabB fabD a [2-oxoglutarate glcNAc-1,6- L,D- keto-D-fructose hydratase A: acnA CoA bacterial LpoA γ ilvA ligase (AMP- glutamine amido- water ligase (AMP- mannitol-1- pyridine nucleotide 2-dehydro-3- dehydrogenase: tdh methyltransferase: methyltransferase: monophosphatase: phosphohydrolase: oxoglutarate bisphosphate [+ 3 more] [+ 3 more] thr RhtC thr 3-deoxy-7- -L-glutamyl reductase: fabI 9 carboxypeptidase: epimerase: folB oxidoreductase: methyltransferase: 1,2-dipalmitoyl- CMP L-glyceraldehyde D-mannose acetolactate metL 3-oxo-cis-∆ - (heptosyl) -Kdo -lipid dehydrogenase anhMurNAcaminidase: 6-phosphate N3- deoxyribonuclease 3'-phosphodiesterase: bifunctional aconitate reductase: ferritin: α,α-trehalose lipid IV (E. coli) + 1-(5-phospho- 2 2 galactitol phosphate 5- rlmA trmJ nudG transaminase: nucleotidase: A Cu forming): asnB ligase (AMP- dikinase: forming): serS 6 fructoselysine 2-acylglycerophosphoethanolamine deoxyribodipyrimidine transhydrogenase: deoxygluconate L-threonine 1 suhB 2+ 2+ phosphoheptulonate 5-phosphate (2Z)-2-aminobut- 3-phosphoserine A phosphate (E. coli) crotonobetainyl- E2 protein] N tartronate a glycerophosphodiester nagZ ldcA methylcytosine V: nfi xthA an N - a 2'-O- hcr cheR fadH ftnA Fe FeoB Fe phosphatidylserine CMP phosphatase: phoA 3-phosphate 6-phosphate synthase: β-D-ribosyl)-ATP hexadecenoyl- a malonyl-[acp] 2-oxoglutarate Metabolic Clusters (S)-malate γ dehydrogenase: hydratase B and 7,8- aspC cysQ synthase: aroH 2-enoate asparagine forming): asnB L-aspartyl- selD a decanoyl-[acyl-carrier protein] semialdehyde L-alanyl- -D- 6-phosphate acyltransferase: aas photolyase: phr sthA aldolase: yagE dehydrogenase: yiaY 745 32 pGp (2E)-dec-2- [FeO(OH) L-glyceraldehyde mannose 6- cuprous glutamate-5- aminotransferase: serC [acp] CoA -lipoyl-L-lysine decarboxylase: transport of demethylase: alkB 2-methylisocitrate methylguanine methylcytidine myo-inositol a reduced hybrid- glu-Me 5'-ribonucleotidase: ushA ilvG ilvM phosphoribosyl-ATP lipopolysaccharide core 1,6-anhydro-N- mtlD deglycase: frlB aminoacetone dihydromonapterin Tap kynurenate AMP trehalase: treA 3-phosphate phosphate LapB 3-deoxy-7- semialdehyde synthetase: asnA 4-phosphate an L-seryl- reductase: caiA tartronate glutamyl-meso- D-galactitol: in 23S rRNA in tRNA cluster protein enoyl-CoA ] monomer Lipid A oxidase: acetolactate selenophosphate β reductase: fabG heptosyltransferase: acetoacetyl-[acp] sucA N-end rule pathway I (prokaryotic) acetyl-β-muramate dehydratase: acnB nucleoside 5'- Polyprenyl Biosynthesis pyrophosphatase: [tRNA sec ] -ketododecanoyl- dihydrolipoate glycerophosphodiester diaminopimelate a 5'-phospho- a deoxyinosine- a [DNA]-3'- phosphatase: phosphatase: cueO phosphoheptulonate dehydrogenase: a (3R,9Z)-3- semialdehyde glycerol gatC + 2-phosphoglycolate palmitoyltransferase: synthase: asn aspartate- O-phospho-L-serine [acp] synthase: fabB waaQ synthase: fabB β-ketoacyl-ACP dehydrogenase: lpd phosphodiesterase: ugpQ anhydro-N- β-D-glucose an L-1- a cytosine in DNA formaldehyde succinate a DNA with NADH NADP D-glyceraldehyde pyruvate D-threo-isocitrate YraQ monophosphate phoA phoA synthase: aroG proA hisI hydroxyhexadec- leucyl- reductase: glxR F6P [DNA] [DNA]-3'-hydroxyl hydroxyl α β pagP FimD ilvB ilvN semialdehyde (heptosyl) -Kdo -lipid synthase: fabH gatB gatA phosphatidylethanolamine nonadjacent thymidines -D-glucopyranose -D-glucopyranose phosphatase: aphA Cu 2+ β asn β-ketoacyl-ACP 3 2 acetoacetyl-[acp] acetylmuramic 6-phosphate lys polyisoprenoid biosynthesis (E. coli) 3-deoxy-D-arabino- 2-iminobutanoate 1-(5-phospho- - 9-enoyl-[acp] tRNA--protein glycerophosphoryl diester L-glyceraldehyde D-mannose L-glutamate-5- dehydrogenase: phosphoserine selenocysteine A-phosphate (E. coli) synthase: fabF a [2-oxoglutarate a [2-oxoglutarate a [protein] D-glycerate glycerol kinase: glpK acid kinase: cytidine D-ribosyl)-AMP synthase: fabF 3-hydroxy cis ∆ 9 transferase: aat phosphodiesterase: glpQ galactitol 1-phosphate fructose-1,6- YgdR heptulosonate semialdehyde (S)-2-acetolactate asd phosphatase: serB synthase: selA dehydrogenase dehydrogenase an N-terminal 2-palmitoyl-sn-glycero- lipopolysaccharide N-terminal L- anmK biphosphate 1 6 an N-terminal L- lipid IV 7-phosphate phosphoribosyl- -hexadecenoyl- E2 protein] N 6 E2 protein] N 6 -S- a [ThiI sulfur- an N - 1,N - an N 10 - a guanine 1207 a uracil 1498 (2-aminoethyl) a uridine 38- (7Z)- N-acetyl-D- B a 3-oxododecanoyl-[acp] glucosyltransferase: an acetoacetyl-[acp] arginyl-[protein] leucyl-L-arginine glycerate N-acetyl-D- galactitol-1- a uracil in tRNA (S)-lactaldehyde cellulose UDP-α-D-glucose a 9S rRNA an isocitrate L-tartrate an aromatic methylglyoxal selenate 3-phosphoserine IPP (2R)-2,3-dihydroxy-3- AMP L-aspartate 4- an L- [acp] phosphatase: carrier protein]-S- 2-oxoglutarate ethyladenine 2-oxoglutarate ethenoadenine alanyl-[S18 protein Tar glu glucosamine YldA 3-dehydroquinate -dihydrolipoyl- succinyldihydrolipoyl- 2-kinase: sn-glycerol 3-phosphate muramate 6- formyltetrahydrofolate in 16S rRNA in 16S rRNA phosphonate 40 in tRNA tetradecenoyl-CoA amino acid methylbutanoate:NADP + semialdehyde ser waaG phosphate 5- phoA aldehyde reductase: yqhD of 30S ribosome] dehydrogenase glyoxalase synthase: aroB cyclohydrolase: selenocysteinyl- dehydratase: biotin-carboxyl carrier L-lysine L-lysine sulfanyl-L-cysteine in DNA in DNA ribosomal-protein- 16S rRNA m 2 G1207 16S rRNA m 3 U1498 (2-aminoethyl) tRNA acyl-CoA L-tartrate N-acetyl-D- selenate RcsF isopentenyl- superpathway of L-lysine, L-threonine and L-methionine biosynthesis I glxK phosphate dehydrogenase: isocitrate chemotaxis protein aromatic- oxidoreductase 2-oxobutanoate sec 3-oxoacyl-[ACP] glucosyl-(heptosyl) - leucyl- fructose-1,6- (S)-lactaldehyde phosphonate N- 38- III: yhbO reductase: a 2'- YjiH hisI homoserine [tRNA ] fabZ 3 protein assembly cellulose S18-alanine N- methyltransferase: methyltransferase: pseudouridine dehydrogenase: dehydrogenase: glucosamine γ-glutamyl-p- a double 3-phospho- L-galactono- ∆ (S)-1-pyrroline- glycerate glycerol-3-phosphate aerobic glycerol N-acetylmuramic 6 amino-acid diphosphate - (isomerizing): ilvC 1-(5-phospho-β-D-ribosyl)- 5,10-methylenetetrahydrofolate:glycine reductase: fabG a (2E,9Z)- Kdo -lipid A-phosphate tRNA--protein gatD bisphosphatase: 1-ethyladenine 1,N - reductase: yahK formyltetrahydrofolate ribonuclease: acetyltransferase: dehydrogenase methyltransferase: ynfE ynfF asn glycyl-glycine deoxyribonucleoside 3-dehydroquinate dehydrogenase: 2 tRNA uridine 4- synthase: acetyltransferase: rsmC rsmE 40 synthase: truA fadE dmlA transaminase: kinase: nagK glyoxalase: nitroanilide stranded DNA D-glycerate 1,4-lactone isomerase: idi 5-carboxylate acetohydroxybutanoate a [biotin carboxyl- a [protein] 2-kinase: dehydrogenase, 3-phosphate acid 6- 6-phosphofructokinase: 2 3 kinase: aceK cheR (2R)-2,3- hydroxymethyltransferase: glyA dihydrolipoyltranssuccinylase: transferase: aat keto-D-tagatose demethylase: ethenoadenine deformylase: purU rne an N - phnO 38- N-acetyl-D- ynfG ynfH asparaginase: iaaA 3'-monophosphate 5-[(5-phosphoribosylamino) oxaloacetate metL hexadeca-2,9- lipopolysaccharide an N-terminal yggF sulfurtransferase: thiI aldehyde reductase: ahr bcsB bcsA an N-terminal N-acetyl-rimI an N - a pseudouridine (2E,7Z)- a phosphorylated 2-hydroxy-3- tyrB hchA synthase: ilvG ilvM carrier protein]-L-lysine N-terminal L- garK anaerobic: glpA glpB glpC dehydrogenase: glpD phosphate pfkA 1207 1498 (2-acetamidoethyl) MokC 2'-deoxyribonucleoside pyrroline-5- dihydroxy-3- methylideneamino]imidazole- a (3R)-3-hydroxydodecanoyl-[acp] dienoyl-[acp] sucB 6-phosphate alkB repair: alkB + methylguanine methyluracil an aromatic glucosamine L-asparaginase: ansA endonuclease 3-phosphoglycerate L-galactono- DMAPP 3-dehydroquinate core heptose a 3-oxoacyl-[acp] L-lysyl-[protein] etherase: murQ fructose 1,6- NADP -dependent L-alanyl-[S18 protein 40 in tRNA tetradecenoyl-CoA isocitrate Tar glu-Me oxosuccinate (R)-lactate selenite carboxylate methylbutanoate acetohydroxybutanoate aspartate gly palmitoleoyl- biotin- leucyl-L-lysine 2-phospho- 6-phosphofructokinase: in 16S rRNA phosphonate 6-phosphate L-asparaginase: ansB γ-glutamyltranspeptidase: 3'-monophosphate I: endA phosphatase: phoA γ-lactonase YahN dehydratase: aroD 4-carboxamide L-homoserine (II) kinase: waaY DHAP N-acetyl-D- bisphosphatase: aldehyde reductase: ybbO of 30S ribosome] in 16S rRNA dehydrogenase 2-oxo-acid reductase: synthase: ilvI ilvH pfkB UDP asp phosphatase: aphA YehB geranyl 2,3-dihydroxy- 1-(5-phosphoribosyl)-5- transaminase: aspC (3R)-3- [acp]:NAD+ glucosyl-(heptosyl) [acetyl-CoA- D-glycerate glucosamine ybhA a [ThiI sulfur-carrier a 4-thiouracil in tRNA (S)-propane-1,2-diol cellulose formate a tetrahydrofolate a 5S rRNA an rRNA fragment ggt L-cysteine biosynthesis VII (from S-sulfo-L-cysteine) acetaldehyde an adenine in DNA succinate glyoxal an adenine in DNA succinate a 2'- a 5'-phosphooligonucleotide D-glycerate L-galactonate diphosphate 3-dehydroshikimate proC isovalerate (S)-2-aceto-2- [(5-phosphoribosylamino) homoserine O- hydroxydodecanoyl- oxidoreductase: -Kdo -lipid A- carboxylase] protein]-L-cysteine 3 2 6-phosphate D-tagatofuranose fructose-1,6- deoxyribonucleoside synthase: ispA dehydratase: hydroxybutanoate methylideneamino]imidazole-4- asp succinyltransferase: [acyl-carrier protein] fabI bisphosphate ligase: birA superpathway of glycolysis and the Entner-Doudoroff pathway N-acetylglucosamine- YnjH shikimate pro a [biotin carboxyl- 6-phosphate bisphosphatase: γ-L-glutamyl- ilvD (R)-2,3-dihydroxy-3- carboxamide isomerase: hisA metA dehydratase: fabZ lipopolysaccharide 1,6- 6-phosphate 4-nitroaniline YmfE geranyl dehydrogenase: ser glpX 3 + a palmitoleoyl-[acp] galactosyltransferase: carrier protein]-N tagatose-6- sulfoquinovose degradation I 6 an N - 6 a (1->4)- an N-terminal L- 2445 746 GDP-4-dehydro- glycylglycine 3-methyl-2- methylpentanoate:NADP aspartate + a [protein]-N - an N -(1-hydroxy-2- a guanine a double-stranded uridine a [protein]- diphosphate phosphoribulosylformimino- O-succinyl-L- 6 D-glucopyranose 6-phosphate Pentose Phosphate Pathways deacetylase: nagA NAD (R)-lactaldehyde maltopentaose 4-hydroxy- a nucleoside 3',5'- 2+ aroE cys a (2E)-dodec-2-enoyl-[acp] -biotinyl-L-lysine phosphate fructose-1,6- 2-oxoglutarate [DNA] α alanyl-[S5 protein cyclic-AMP Tsr glu pyrazinamide mutated tRNA α-D-rhamnose Cu oxobutanoate oxidoreductase kinase: lysC waaB acetyl-L-lysine methylcytosine oxopropyl)-[protein]-L-lysine -D-glucan in 23S rRNA oligonucleotide in 23S rRNA bisphosphate L-glutamine YzcX AICAR-phosphate homoserine serine galactosyl-(1->6) β-ketoacyl-ACP 3-oxoacyl-[ACP] D-glucosamine kinase: pfkB bisphosphatase: fbp 1-(6-sulfo-α- aldehyde reductase: yqhD L-threonine GDP-L- farnesyl (isomerizing): ilvC in RNA 3' to 5' proofreading of 30S ribosome]ribosomal-protein- 23S rRNA m 2 G2445 23S rRNA cAMP 3',5'-nucleoside protein- NADH shikimate aspartate acetyltransferase: dodecanoyl-[acyl- synthase: fabF reductase: fabG glucose-6-phosphate pentose phosphate pathway 6-phosphate D-quinovosyl) oligoribonuclease: chemotaxis protein RNase BN poly-[(R)-3- diphosphate 3-oxo-cis- -glucosyl-(1->3)- D-tagatofuranose β-D-fructose 1,6- (R)-lactaldehyde exonuclease: polA 746 pyrazinamidase: glutamine fucose cupric AmpE glycyl-glycine glutathione an mRNA an aldose 2'CMP 2-isopropylmalate valine (R)-2,3-dihydroxy- kinase: metL cysE protein-lysine maltodextrin S5-alanine N- methyltransferase: 4-hydroxythreonine pseudouridine phosphodiesterase: bisphosphate asn YdiM synthase: ispA imidazole O-succinylhomoserine(thiol) carrier-protein] vaccenoyl- (heptosyl) -Kdo - β-ketoacyl-ACP isomerase: pgi phosphoglucosamine 1,6-bisphosphate bisphosphate glycerol N3- protein deglycase: hchA maltopentaose orn methyltransferase: pncA ribonuclease: synthase: hydroxybutanoate] shikimate synthase: leuA transaminase: 3 2 a [biotin carboxyl- reductase: yahK DNA polymerase: polB glucosidase: acetyltransferase: rlmL kinase: thrB synthase: rluA cpdA phosphatase: glutaminase: reductase: asparaginase: iaaA 2'CMP 3-methylpentanoate aspartate + glycerol -lyase: metB reductase: fabI synthase: fabB D-glucopyranose Aromatic Compound Degradation fructose- deacetylase: protein deglycase: yhbO glucosidase: malZ 2 cheR rbn poly-3- kinase: aroK [acp] lipid A-bisphosphate NADP -dependent glucose-6-phosphate mutase: glmM methylcytosine aldehyde reductase: ahr an N - 746 cheB fcl ndh aldose sugar (2E,6E)-farnesyl ilvE kinase: thrA O-acetyl-L-serine carrier-protein dimer]- sulfoquinovosidase: 3' to 5' proofreading malZ an N-terminal N-acetyl-rimJ a nucleoside 5'- a pseudouridine yciV pyrazine-2- L-asparaginase: ansA RNase I phosphatase: 2,3-dihydroxy-3- thiosulfate palmitoleate a 2,3,4-saturated a (3R)-3-hydroxyacyl- 6-phosphate DHAP bisphosphate cobB 2445 4-phosphooxy- α hydroxybutyrate phosphate synthase: UDP-D- 6 glucose-6-phosphate isomerase: kduI tagatose-1,6- demethylase: alkB protein deglycase: yajL + AMP a nucleoside 5'- a nucleoside 5'- a [protein]- - β + dehydrogenase: yliI diphosphate shikimate (2S)-2- N -biotinyl-L-lysine α-D-glucosamine NADP -dependent exonuclease: dnaQ methylguanine in 23S rRNA glu-Me carboxylate GDP- -L-fucose Cu L-asparaginase: ansB γ-glutamyltranspeptidase: endoribonuclease: rna phoA methylvalerate a dodecanoyl-[acp] fatty acyl-[acp] + yihQ L-alanyl-[S5 protein monophosphate Tsr synthase: ydcS synthase: glutathione fabF glucose:(glucosyl) (3R)-3- [acyl-carrier protein] dehydrogenase: zwf NADP -dependent superpathway of bisphosphate aldolase: fbaB a 2'-deoxyribonucleoside in 23S rRNA L-threonine monophosphate monophosphate L-glutamate thiamine YfgH kinase: aroL isopropylmalate L-aspartyl-4-phosphate L-cystathionine acetyl-CoA biotin 3-phenylpropanoate and 3-(3- 1-phosphate aldehyde reductase: ybbO a (1->4)- of 30S ribosome] asp ggt cytidine FrvR hydro-lyase: ilvD hisH hisF LPS α-1,3- hydroxyacyl-[acyl- glucose-6- phenylethylamine aldolase: gatY fructose 2''-O-acetyl- D-glucopyranose maltotetraose thiamine ABC thiamine an aldonate poly-[(R)-3- val S-sulfo-L-cysteine β-ketomeristoyl- carboxyltransferase: carboxylase: F6P hydroxyphenyl)propanoate degradation triose- 6-sulfo-α-D- (R)-propane-1,2-diol 5'-monophosphate α D-glucopyranose an mRNA fragment ditrans,polycis all-trans- (2S)-2- an (11Z)-3- glucosamine- ADP-ribose nicotinamide a [protein]-L-lysine formaldehyde a cytosine in RNA succinate (R)-lactate a [protein]-L-lysine -D-glucan hydroxybutanoate] shikimate 3-phosphate (3S)-3-methyl-2- glucosyltransferase: carrier protein] phosphate degradation tagatose-1,6- bisphosphate quinovose glycerol transporter -undecaprenyl- octaprenyl- isopropylmalate D-erythro-1- aspartate- cystathionine synthase: cysM [acp] synthase: fabB enoyl-[acyl- accA accD accC 1-phosphate phosphate oxopentanoate L-isoleucine biosynthesis oxooctadec- waaO dehydratase: fabZ a [carboxyl-carrier fructose-1,6- dehydrogenase: 3-phenylpropanoate bisphosphate aldolase: fbaA γ-L-glutamyl- diphosphate diphosphate hydro-lyase (2- AICAR (imidazol-4- semialdehyde β-lyase: malY β-ketoacyl-ACP carrier-protein] 2-phenylethylamine acetyltransferase: isomerase: L-cysteinylglycine 3-phosphoshikimate 1- isoleucine I (from threonine) 11-enoyl-[acp] galactosyl-(glucosyl) 6 bisphosphatase: yggF zwf autoinducer AI-2 degradation glycylglycine L-valine synthase: ispB isopropylmaleate- synthase: fabF 2,3,4-saturatedreductase: fabI 3-hydroxyacyl- protein dimer]-N - 6-phospho D-glucono-1,5-lactone glmU aldolase: kbaY tpiA YaiP val val synthase [(2E carboxyvinyltransferase: transaminase: yl)-glycerol dehydrogenase: asd cystathionine 3-oxo-cis- -(heptosyl) -Kdo - 6-phospho 3-phenylpropionate a 5,10- a 2-thiouridine 34 sn-glycero-3- hydrogen a dimer of adjacent a guanine 1835 a uridine 516 RNase II a double S-sulfo-L-cysteine a glutaredoxin dithiol 2 3 2 fatty acyl- [acp] a (3R)-3- carboxybiotinyl-L-lysine fructose 1,6- 6-phosphofructokinase: menadiol ν maltohexaose maltose an aldehyde melibionate an oxidized an oligopeptide histidinol thiamine AcrZ exporter ,6E)-farnesyl- forming): leuC leuD 3-phosphate β-lyase: metC vaccenoyl- N-acetyl-α-D- 6-sulfo-D- h glyoxylate TsaD shikimate degradation thiosulfate L-tartrate aroA ilvE lipid A-bisphosphate dehydratase: fabA bisphosphatase: ybhA pfkA D-glucono- 3-(3-hydroxyphenyl) dioxygenase: hcaC methylenetetrahydrofolate in tRNA phosphoethanolamine peroxide thymidines in DNA in 23S rRNA in 16S rRNA stranded DNA all-trans- imidazoleglycerol- L-aspartate 4-semialdehyde thr a 3-oxotetradecanoyl-[acp] [acp]:NAD+ hydroxydecanoyl-[acp] 6-phosphogluconolactonase: glucosamine D-glyceraldehyde quinovose AI-2 + flavorubredoxin cytidine 2',3'-cyclic diphosphate [acp] lipopolysaccharide 1,5-lactone phenylacetaldehyde propanoate hcaD hcaF hcaE NADP -dependent 23S rRNA m 2 G1835 shikimate 16S rRNA substrate mRNA thiosulfate histidinol L(+)-tartrate thiamine an L-1- a single- 2-phospho- octaprenyl 5-enolpyruvoyl- 2-isopropylmaleate threonine oxidoreductase: pgl fructose-1,6- 6-phosphofructokinase: 3-phosphate autoinducer- H O 2'-UMP specific]: ispU phosphate L-homocysteine glucosyltransferase: 3-hydroxydecanoyl- 1-phosphate aldehyde reductase: ybbO 2-hydroxyglutarate 516 oligopeptidase: gyrase: 2 monophosphate YniB ile S-sulfo-L-cysteine reductase: sulfoquinovose NADH:flavorubredoxin methyltransferase: metallopeptidase: dehydrogenase: pseudouridine exoribonuclease sulfurtransferase: dehydrogenase: dehydratase: kinase: diphosphate phosphatidylethanolamine stranded RNA D-glycerate diphosphate shikimate 3-phosphate deaminase: 3-oxoacyl-[ACP] fabI [acp] bisphosphatase: glpX pfkB 6-phosphogluconolactonase: 3-(5,6-dihydroxycyclohexa- glyceraldehyde- 2 kinase: lsrK 5-aminomethyluridine- menadiol:hydrogen amylomaltase: α-galactosidase: synthase ptrB gyrA gyrB cytidine 2',3'-cyclic 2'UMP (2S)-2- dehydratase: hisB reductase: grxA fabG waaJ 3-(3- N-acetylglucosamine- isomerase: yihS (2S)-2-hydroxy- L-1-glycerophophorylethanolamine deoxyribodipyrimidine aldehyde reductase: ahr reductase: norW rlmG tsaB ydiB synthase: rsuA II: rnb glpE hisD ttdA ttdB thiK 3-(imidazol-4- 4-hydroxy- homoserine ilvA D-gluconate 6-phosphate fructose-1,6- pgl 1,3-dien-1-yl)propanoate tRNA synthase: peroxide malQ melA YfdY phosphatase: di-trans,octa-cis chorismate cobalamin- (2Z)-2-aminobut- reductase: fabG a (3R,11Z)-3- galactosyl-(glucosyl) dehydrase: fabA 1-phosphate 3-phosphate 3,4-dioxopentyl phosphodiesterase: ugpQ photolyase: phr aldehyde reductase: yahK an N 2 - RNase I phosphodiesterase: phosphoglycerate phosphatase: isopropylmalate hydroxyphenyl) 6-deoxy-6- mnmE mnmG oxidoreductase: ccp a 16S rRNA a negatively thiamine phoA -undecaprenyl yl)-2-oxopropyl tetrahydrodipicolinate dehydrogenase: metL cobalamin- independent -(heptosyl) -Kdo - a trans-2-enoyl- bisphosphatase: fbp D-gluconate dehydrogenase: 1835 2-hydroxyglutarate TsaD degradation 3-dehydroshikimate a nucleoside 5'- sulfite oxaloacetate endoribonuclease: rna cpdB phosphatase: phoA phoA synthase: 2-enoate hydroxyoctadec- 3 3 2 (3R)-3- uridyltransferase: phosphate aldehyde reductase: yqhD a reduced methylguanine 516 a peptide his phospholipase MipA hydro-lyase (2- phosphogluconate propanoate 2,3-dihydroxy-2,3- sulfo-D-fructose pseudouridine supercoiled DNA phosphate phosphate diphosphate aroC phosphate synthase: dapA homoserine dependent homocysteine cys 11-enoyl-[acp] lipid A-bisphosphate [acyl-carrier protein] fructose- 6-phosphate phenylacetaldehyde gapA (4S)-4-hydroxy-5- flavorubredoxin products monophosphate A2: pldA uridine YpjK isopropylmaleate- a (3R)-3-hydroxytetradecanoyl-[acp] hydroxydecanoyl- dehydratase: edd β-D-fructose 1,6-bisphosphate hydroxylase: dihydrophenylpropionate glmU an alcohol α-D- in 23S rRNA 3'-cmp histidinol-phosphate dehydrogenase: thrA methionine ADP-heptose:LPS 6-deoxy-6- phosphonooxypentane- two adjacent maltoheptaose D-glucopyranose D-gluconate an rRNA fragment D-glycerate undecaprenyl forming): leuC leuD transmethylase: 3-hydroxy cis [acyl-carrier bisphosphate 6-phosphogluconate mhpA UDP-N-acetyl- a 5-(aminomethyl)-2- ethanolamine sn-glycerol galactopyranose chorismate aminotransferase: (2S,4S)-4-hydroxy-2,3,4,5- synthase: heptosyltransferase phenylacetaldehyde dehydrogenase: hcaB 13-DPG sulfofructose a 7,8-dihydrofolate menadione H O pyrophosphate superpathway of L-aspartate metE (3R)-3- vaccenoyl- protein] aldolase: fbaB dehydrogenase, α-D-glucosamine 2,3-dione isomerase: lsrG thiouridine 34 in tRNA 3-phosphate 2 thymidines in DNA YgbN KDGP kinase: yihV phosphatase: (2R,3S)-3- and L-asparagine biosynthesis hisC tetrahydrodipicolinate metH hydroxymyristoyl- [acp] 4: waaU dehydrogenase: feaB 3-hydroxy-2,4- a 1-acyl-2-lyso- cobalamin- 2-iminobutanoate lipid A-core dehydratase: fabZ fructose decarboxylating: gnd UDP-N-acetylglucosamine a fatty acid isopropylmalate L-homoserine 2,3-DHP phosphoglycerate 6-deoxy-6- dioxopentyl phosphatidylethanolamine pgpB chorismate anthranilate L-histidinol 4-hydroxy- dependent [acyl-carrier protein] dehydratase: bisphosphate D-ribulose 1-carboxyvinyltransferase: EcnA oligosaccharide (E. phenylacetate sulfo-D-fructose 6 1518 DNA combined with 1516 3-isopropylmalate tetrahydrodipicolinate fabZ DHAP kinase: pgk phosphate a [protein]- a DNA methyl a [protein]-N - adenine / a guanine DNA containing an aliphatic a C-nitro MlaA undecaprenyl mutase: tyrA synthase: glu phosphate methionine L-glutamate biosynthesis I dehydratase: fabZ a (2E)-dec-2-enoyl-[acp] 2-keto-3- aldolase: fbaA 5-phosphate murA quercetin glutathione maltohexaose maltose aminoacetone an oligopeptide DHAP a DNA segment D-tartrate (R)-NADPHX (S)-malate fumarate coli K-12 core type) 2,3-dihydroxyphenylpropionate 1-phosphate 3-hydroxy-2,4- 1519 exogenous DNA to form ser α ω pyrophosphate trpE trpD dehydrogenase reductase: dapB synthase: a (2E,11Z)- deoxygluconate α L-cysteine phosphotriester monoubiquitinyl-L-lysine adenine in 16S rRNA in 16S rRNA a recognition site , -diamine compound uridine 2'3'-cyclic chorismate histidinol- homoserine O- homoserine phenylacetate- UDP-N-acetyl- - 6 an L-1- (decarboxylating) a (2E)-tetradec-2-enoyl-[acp] octadeca-2,11- trans-2- 1,2-dioxygenase: mhpB 3-phospho-D-glycerate pentadione 16S rRNA m a recombinational junction 16S rRNA m 2 G1516 type IV D-aminopropanol diamine N- NAD(P)H D-tartrate NADPHX malolactic GspB 2-phenylethylamine a 23S rRNA phosphocholine phosphatase: mutase: pheA metH 6-phosphate triose-phosphate ribulose- ribose-5- D-glucosamine- 2 monophosphate YqiH phosphatase: (S)-2,3,4,5-tetrahydrodipicolinate succinyltransferase: kinase: thrB CoA ligase: paaK 6-deoxy-6- A1518,m 6 A1519 3-hydroxy acid oligopeptidase: methylglyoxal recombinase: phosphatidylethanolamine : dmlA 2-oxobutanoate dienoyl-[acp] decenoyl-ACP 5-phosphate 2 resolvasome: methyltransferase: deoxyribonuclease: dehydrogenase: acetyltransferase: nitroreductase: dehydratase: epimerase: enzyme: phenylethylamine ybjG aspartate aspartate gln aldolase: eda isomerase: tpiA phosphate 3- phosphate (2Z,4E)-2-hydroxy-6- enolpyruvate quercetin 2,3- methylphosphotriester- glutathione-specific γ- maltohexaose amylomaltase: dehydrogenase prlC uridine 2',3'-cyclic RclC anthranilate hisB metA myristoyl-[acyl- 2,3-bisphosphoglycerate- sulfofructose- thiolase: lsrF deubiquitinase: dimethyltransferase: synthase: mgsA pinE phosphocholine 3-isopropylmalate transaminase: ammonia- cis-vaccen- isomerase: fabA phenylacetyl-CoA oxonona-2,4-diene-1,9-dioate dioxygenase: DNA-protein-cysteine S glutamylcyclotransferase: ruvC ruvB ruvA rsmJ mcrA gldA speG nfsB fumB nnr maeB oxidase: tynA RNase I phosphodiesterase: undecaprenyl tetrahydrodipicolinate cys met epimerase: isomerase UDP-N- independent phosphoglycerate 1-phosphate glucosidase: malZ malQ 2 YdfG: ydfG phosphatase: prephenate acetohydroxybutanoate carrier-protein] 2-enoyl- elaD 6 rsmA 1518 resolution of recombinational an N - a hydroxylamino a DNA segment anthranilate dehydrogenase: aspC lyase: aspA histidinol O-phospho-L-homoserine L-glutamate:NADP+ rpe A: rpiA mutase: gpmA yhhW methyltransferase: ada chaC N -dimethyladenine DNA cleaved at (R)-1- an aliphatic N- phenylacetaldehyde phospholipase endoribonuclease: rna cpdB OmpW pyrophosphate succinylase: dapD synthase: ilvG ilvM reductase: fabI a (3Z)-dec-3-enoyl-[acp] D-glyceraldehyde 3-phosphate 2-hydroxy-6- acetylenolpyruvoylglucosamine phosphoglycerate aldolase: yihT DHAP methylguanine 1516 2-aminoacetaldehyde group-containing a peptide methylglyoxal in reverse oxaloacetate (S)-NADPHX (S)-lactate phoA [acp] phenylacetyl- /N 6 -dimethyladenine 1519 junction formation recognition site aminopropan-2-ol acetyl-diamine phosphatase: phosphoribosyl leuB O-succinyl-L-homoserine oxidoreductase ketonona-2,4- reductase: murB mutase: gpmM YggE A1: pldA 3'-UMP histidinol acetohydroxybutanoate reductase: ribose-5- CoA 1,2- of two intact strands in 16S rRNA compound orientation an rRNA fragment choline (transaminating) 5 glyceraldehyde- D-xylulose in 16S rRNA bacA prephenate prephenate transferase: trpD (2S)-2-isopropyl- N-succinyl-2-amino-6-ketopimelate threonine a myristoyl-[acp] β-keto-cis-∆ - phosphate dienedioate UDP-N-acetyl- (2S)-3- a [protein]-S- a [ubiquitin] C- D-glucopyranose maltopentaose D-glucopyranose maltotriose LapA asp dehydrogenase: synthase: ilvI ilvH : gltB gltD fabI epoxidase: DHAP 2-protocatechuoylphloroglucinolcarboxylate CO [DNA] 5-oxo-L-proline L-cysteinylglycine a [protein]-L-lysine di-trans,octa-cis dehydratase: dehydrogenase: N-(5-phosphoribosyl) 3-oxosuccinate synthase: thrC 3-phosphate 5-phosphate hydrolase: mhpC α-D-muramate 2-phospho-D-glycerate sulfolactaldehyde terminal glycine hisD N-succinyldiaminopimelate (S)-2-aceto-2- dodecenoyl-[acp] isomerase: paaE paaA methyl-L-cysteine a 2-acyl-1-lyso- -undecaprenyl pheA tyrA O-succinylhomoserine(thiol) β-ketopalmityl-[acp] a cis- dehydrogenase: gapA a fatty acid -anthranilate L-aspartate:ammonia aminotransferase: serC 2-oxoglutarate ammonium synthase: fabB rpiB (2Z)-2-hydroxypenta- 3-sulfolactaldehyde phosphatidylethanolamine phosphate -lyase: metB hydroxybutanoate synthase: fabB vaccenoyl-[acp] paaC paaB UDP-N- histidinal thr 2,4-dienoate enolase: eno SlyB phosphoribosylanthranilate ligase (AMP- N-succinyldiaminopimelate (R)-2,3-dihydroxy-3- a (5Z)-3-oxododec- 2-(1,2-epoxy-1,2- acetylmuramate:L- reductase: yihU an N 6 -L- TorY 3-phenyl-2- 3-(4-hydroxyphenyl) β-ketoacyl-ACP 13-DPG D-ribose 5- N-acetyl-D- UDP-N-acetyl- 6-(glutathion-S-yl)-2- 2-O-(α-D-glucopyranosyl) a guanine 2069 DNA containing a negatively ethyl-2- a uridine 34 5-nitro forming): asnB + 2-oxopent- γ a peptidoglycan maltoheptaose 37 2-oxoglutaramate L-quinate (S)-NADPHX ATP YkiC oxopropanoate isomerase: trpC 4-methyl-2- histidinol aminotransferase: argD methylpentanoate:NADP 5-enoyl-[acp] dihydrophenyl) alanyl- -D- (2S)-2,3- α-D-glucosamine glutathione threonylcarbamoyladenine D-phenylhydantoin ser an acyl phosphate 5-oxo-L-proline 2'-deoxycytidine pyruvate L-glutamine L-glutamate:NADP+ synthase: fabF phosphate 4-enoate glucosamine methylhydroquinone -D-glycerate in 23S rRNA a recognition site supercoiled DNA methylacetoacetate in tRNA benzisoxazole 1-(2- oxopentanoate asparagine dehydrogenase: L-cystathionine oxidoreductase 5 acetyl-CoA glutamyl-meso- phosphoenolpyruvate dihydroxypropane- in tRNA topoisomerase: aminoacetone a β-D glucoside 2-phosphoglycolate a sugar phosphate phenylalanine tyrosine biosynthesis I oxidoreductase 3-oxo-cis-∆ - phosphoglycerate 23S rRNA m 7 G2069 type IV quinate 5-oxoprolinase: β-keto ester tRNA U34 (S)-NADPHX Kemp adenylate 3'-monophosphate Ag43 N-succinyl-L,L-2,6-diaminopimelate ring 1,2- hydratase: mhpD 1-sulfonate tRNA m 6 t 6 A37 phenylhydantoinase: serine deaminase: tdcG carboxyphenylamino) leucine synthetase: asnA hisD (isomerizing): ilvC (deaminating): gltB gltD a 3-oxohexadecanoyl-[acp] dodecenoyl-[acp] kinase: pgk transketolase: diaminopimelate acylphosphatase: 2-oxoglutaramate topB pxpC aminoacetone 2'-deoxycytidine 3'- transaminase: aminotransferase: cystathionine S-glutathionyl- methyltransferase: L-serine deaminase: sdaA methyltransferase: deoxyribonuclease: dehydrogenase: reductase: hydroxylase: dehydratase: eliminase: cyclase: phosphosugar -1-deoxy-D-ribulose aminotransferase: cis-vaccenate tktB epoxyphenylacetyl- (S)-4-hydroxy- ligase: mpl pyruvate N-acetylglucosaminyltransferase: lysozyme: glucosylglycerate maltoheptaose hyuA yccX amidase: yafV topoisomerase: oxidase: tynA 2-phosphoglycerate monophosphate ilvE aspC succinyl- β glu (R)-2,3-dihydroxy- reductase: fabG hydroquinone serine deaminase: tdcB rlmL mcrB mcrC ydiB pxpB pxpA dkgA trhO nnr pdxI cyaA YbcH phosphatase: YjbH 5-phosphate asn -lyase: malY CoA isomerase 2-oxopentanoate phosphoenolpyruvate kinase: pykF pgaD pgaC rrrD glucosidase: malZ trmO 7 β tyrB his 3-methylpentanoate 3-phospho-D-glycerate transketolase: Amine and Polyamine Degradation phosphorylase: ycjM 6 an N - topA a 5- methylglyoxal -D-glucoside phosphatase: phoA phosphatase: aphA DolP phenylalanine tyrosine diaminopimelate glutamine 3-oxoacyl-[ACP] a (3R,5Z)-3-hydroxydodec- UDP-N-acetyl- reductase: yqjG an N -methyl- N-carbamoyl-D- ethyl-(2R)-methyl-(3S) 2-cyano-4- phoA indole-3- cystathionine L-serine biosynthesis I tktA (oxepin-CoA 4-hydroxy-2- synthetase: ppsA pyruvate L-serine deaminase: sdaB 2069 cleaved DNA a carboxylate 2-oxoglutarate 3-dehydroquinate 34 NADPH cyclic-AMP glucohydrolase: bglX leucine desuccinylase: dapE synthetase: 2,3-dihydroxy-3- glu reductase: fabG α-D-muramoyl- threonylcarbamoyladenosine methylguanine a relaxed DNA glu -hydroxybutanoate hydroxyuridine nitrophenol 2'-deoxycytidine transaminase: aminotransferase: asparaginase: β-lyase: metC 5-enoyl-[acp] 2,3-bisphosphoglycerate- forming): paaG phenylglycine pyruvate a sugar glycerol transaminase: L-cysteine biosynthesis I oxovalerate γ kinase: pykA allantoin degradation poly-β-1,6- N-acetyl-D- a N-acetylmuramoyl- in 23S rRNA in tRNA glycolate aspC tyrB iaaA glnA methylvalerate ∆ 5 phosphoglycerate D-sedoheptulose D-glyceraldehyde L-alanyl- -D- UDP α-D-glucopyranose 37 in tRNA phosphate superpathway of L-alanine biosynthesis 3-hydroxy cis - independent 2-oxepin-2(3H)- aldolase: mhpE superpathway of N-acetylglucosamine, D-glucopyranose maltohexaose histidine ilvE L,L-diaminopimelate 3-phospho-D-glycerate gln hydro-lyase: ilvD a (3R)-3-hydroxyhexadecanoyl-[acp] 7-phosphate 3-phosphate glutamyl-meso-2,6- IV (anaerobic) N-acetyl-D- glucosamine pentapeptide- D-glycerate phenylalanine L-asparaginase: L-homocysteine dodecenoyl-[acp] phosphoglycerate mutase: gpmA pyruvate N-acetylmannosamine and N- ethanolamine utilization toluquinol GSSG 1-phosphate DmsD D-glucopyranose a non glucosylated his ABC his synthase: trpC ylideneacetyl-CoA cinnamate and 3-hydroxycinnamate diaminopimelate glucosamine diphosphoundecaprenol aminotransferase: tyr ansA ser D-3-phosphoglycerate (3S)-3-methyl-2- 3-methyl-2- dehydratase: fabZ mutase: gpmM acetaldehyde acetylneuraminate degradation D-glucose acceptor transporter (1S,2R)-1-C-(indol-3- leu (3R)-3- oxepin-CoA degradation to 2-hydroxypentadienoate (S)-(+)-allantoin RsxG tyrB L-asparaginase: diaminopimelate cobalamin- dehydrogenase: serA oxopentanoate oxobutanoate transaldolase: N-acetyl-β- ile ile yl)glycerol 3-phosphate a (2E,5Z)-dodeca- hydrolase: ethanolamine serine epimerase: dapF cys hydroxypalmitoyl- talA acetaldehyde neuraminate β a [DNA]- 1915 1618 ansB independent cobalamin- 3-phosphooxypyruvate isoleucine valine 2-phospho-D-glycerate ADP-L-glycero- - glucosyl-(heptosyl) - 2-hydroxycyclohepta-1,4,6- a dimer of adjacent 2'- a 2,3,4-saturated dUMP a pseudouridine adenine a 5' diphospho- 3-methylbutanoyl- (5Z)- a 1,2-diacyl- val BrnQ val [acyl-carrier protein] 3,5-dienoyl-[acp] paaZ dehydrogenase cinnamate allantoinase: N-acetylneuraminate 2 hν acetate [DNA] a cytosine in DNA an arylamine 8-oxo-dGTP riboflavin isoguanine dodecyl sulfate two reduced thymidine 3'- 2'-deoxyuridine 3'- phe acetyltransferase: homocysteine dependent transaminase: transaldolase: ethanolamine D-manno-heptose Kdo -lipid A-phosphate triene-1-carboxyl-CoA nucleotide- L-allo-threonine an electron- a [reduced an [oxidized 2,3- chitin transaminase: 2 deoxycytidines in DNA fatty acyl CoA in 23S rRNA in 23S rRNA [mRNA] CoA dodecenoyl-CoA sn-glycerol leu leu 5 3-oxo-5,6- allB anomerase: nanQ dUMP cysteine residues monophosphate monophosphate ElfD indoleglycerol cysE dehydratase: fabZ ∆ (acetylating) 3'-phosphate 3 6 YhgN dihydroxybenzoate asp meso-diaminopimelate transmethylase: metE methionine 3-phosphoserine ilvE ilvE cis- -dodecenoyl- enolase: eno talB aldehydo-N- ammonia- 23S rRNA m Ψ1915 type I site-specific 23S rRNA m A1618 DNA-cytosine RNA arylamine N- isovaleryl-CoA acyl-CoA 8-oxo-dGTP riboflavin isoguanine transfer quinone DsbB protein] DsbA protein] phosphate didehydrosuberyl- : mhpF cinnamate phosphohydrolase: yfbR 3'-phosphomonoesterase: 3-hydroxy acid diacylglycerol in a protein 2'-deoxyribonucleoside 2'-deoxyuridine 3'- leucine / L- synthase: metH aminotransferase: serC L-glutamate L-cysteine:[protein [acp]:NAD+ allantoate acetylneuraminate lyase: eutB eutC lipopolysaccharide core methyltransferase: deoxyribonuclease: methyltransferase: methyltransferase: phosphohydrolase: acetyltransferase: dehydrogenase: dehydrogenase: diphosphatase: reductase: deaminase: 2,3-dihydroxybenzoate:oxygen endochitinase: leu leu O-acetyl-L-serine cobalamin- pyruvate a (2E)-hexadec-2-enoyl-[acp] CoA semialdehyde dioxygenase: 2-hydroxycyclohepta- 5'-deoxynucleotidase: yfdR xthA dehydrogenase kinase: dgkA 3'-monophosphate monophosphate phenylalanine aldolase: trpA alanine racemization hydrogen sulfide biosynthesis III ile cysteine] oxidoreductase: D-erythrose acetaldehyde deoxyribodipyrimidine acetate CoA- chiA phe phe diaminopimelate dependent val F6P 3-oxo-5,6- hcaC hcaD N-acetylneuraminate heptosyltransferase: 1,4,6-triene-1-carboxyl- 3'-phosphomonoesterase: rlmH hsdM hsdR hsdS rlmF dcm rppH nhoA aidB fadE mutT fre codA oxidoreductase: cueO phosphatase: aphA phosphatase: aphA YfeN ABC transporter ser O-phospho-L-serine sulfurtransferase: fabI phosphoenolpyruvate 4-phosphate dehydrogenase: allantoate acetaldehyde photolyase: phr transferase 2'-deoxyribonucleoside an N 3 - a double stranded an N 6 - YdfG: ydfG a 1,2-diacyl- decarboxylase: lysA methionine palmitoyl-[acyl- dehydrosuberyl- hcaF hcaE lyase: nanA waaQ CoA thioesterase: paaY nfo a 5-methylcytosine a 5'-phospho- an N- 3-methylcrotonyl- (2E,5Z)- thymidine 2'-deoxyuridine eutE amidohydrolase: 5'-monophosphate 1915 DNA with 5'- methyladenine 1618 8-oxo-dGMP sn-glycerol reduced riboflavin xanthine dodecan-1-ol 2-oxoglutarate iscS glutamate--pyruvate transketolase: CoA semialdehyde N-acetyl-D- a [DNA]-3'- methylpseudouridine [mRNA] acetylarylamine CoA dodecenoyl-CoA aminoacetone 2-carboxymuconate a chitodextrin indole O-acetylserine synthase: metH glutamate carrier-protein] a (5Z)-dodec-5-enoyl-[acp] phosphoenolpyruvate pyruvate kinase: pykF (2E)-3-(5,6- phosphatase: aphA in DNA PspC ile branched chain ile ala phosphoserine L-cysteine aminotransferase: alaC valine--pyruvate tktA allC hydroxyl in 23S rRNA terminal phosphate in 23S rRNA 3-phosphate sulfhydrylase: cysM lys reductase: fabI synthetase: ppsA pyruvate kinase: pykA dehydrogenase: acetyl-CoA dihydroxycyclohexa- mannosamine acetaldehyde ethanol glucosyl-(heptosyl) - val amino acid / val alanine racemase: dadX dehydrogenase: 3 2-hydroxycyclohepta- two adjacent 2'- a 2,3,4-saturated 2'-deoxyuridine met phosphatase: serB desulfurase: glutamate--pyruvate aminotransferase: transketolase: paaZ 1,3-dien-1-yl) (S)-ureidoglycine N-acetylmannosamine dehydrogenase dehydrogenase: ADP Kdo -lipid A-phosphate coenzyme A acetyl-CoA leu phenylalanine leu tryptophan alanine racemase: alr O-acetylserine gdhA 2 1,4,6-triene-1-carboxylate deoxycytidines in DNA fatty acid sufS aminotransferase: alaA avtA a palmitoyl-[acp] pyruvate tktB 3-oxo-5,6- prop-2-enoate kinase: nanK (acetylating) adhP PqiC phe ABC transporter phe synthase: trpB alanine racemase: metC sulfhydrylase: cysK glu didehydrosuberyl- ser D-glyceraldehyde (S)-ureidoglycine N-acetyl-D- : mhpF ethanol alanine racemase: malY CoA 3-hydroxycinnamate YceO 3-phosphate cis-3-(2- aminohydrolase: 1402 YhaV endonuclease trp trp mannosamine acetaldehyde dehydrogenase: an L-1- a pyrimidine nucleoside UTP a cytidine 2-methyl-1,4- D-ala ala cellulose 7 kojibiose lactulose long chain a primary alcohol a uracil 54 in tRNA GSSG Cu 2+ trp cys 3-oxo-5,6- carboxyethenyl) allE 6-phosphate adhE an N -methylguanine in DNA coproporphyrinogen III 1,3-propanediol pantetheine degradation 8-oxo-dGDP enol-oxaloacetate (S)-NADHX tyr AroP tyr dehydrogenase: phosphatidylethanolamine polyphosphate UTP in 16S rRNA benzoquinone dehydrosuberyl- -3,5- alcohol 4 5 substrate mRNA phe phe 3-hydroxy- N-acetylmannosamine- adhE 16S rRNA m C1402 tRNA(m U54) 1,3-propanediol NAD(P)H:quinone 8-oxo-dGDP oxaloacetate (S)-NADHX glutathione cupric thiol:disulfide CoA (S)-ureidoglycolate pyrophosphatase: yhdE porphyrinogen pantetheine trans- cyclohexadiene- 6-phosphate 2- lactulose ribosylpyrimidine dehydrogenase: adhE methyltransferase: methyltransferase: dehydrogenase: oxidoreductase: ribonuclease: diphosphatase: keto-enol- reductase: reductase: acetaldehyde ethanol celulose kojibiose exopolyphosphatase: ppx nucleoside triphosphate dehydratase: oxidoreductase: YpjA phe PheP phe thiolase: paaJ cinnamate 1,2-diol epimerase: nanE DNA-N 7 -methyguanine nucleosidase: rihB alcohol peroxidase: yfeX kinase: coaA isomerase: ureidoglycolate dehydrogenase: phosphoethanolamine phosphorylase: galactohydrolase: rsmH trmA yqhD qorB yhaV mutT nnr gor rclA MreB dsbA pyrophosphohydrolase: 4 trans-2,3- hydroxylase: dehydrogenase: N-acetyl-D- glycosylase: ycaQ dehydrogenase: adhP an N - 54 fumA dehydrogenase: eutE allantoin degradation transferase: bcsG ycjT lacZ a 5-methyluracil methyl-1,4- an electron- an [oxidized a [reduced an intra- trp trp Signal transduction pathways glucosamine long chain mazG 1402 coproporphyrin III 3-hydroxypropanal 4'-phosphopantetheine 8-oxo-dGMP NADH glutathione Cu + Mtr dehydroadipyl-coA mhpA hcaB allD to glyoxylate III an aldehyde methylcytidine in tRNA benzoquinol an mRNA fragment oxaloacetate transfer quinol DsbB protein] DsbA protein] protein disulfide indole indole 6-phosphate a pyrimidine base polyphosphate UMP 2,3- β D-ribofuranose in 16S rRNA N-carbamoyl- N-acetylglucosamine- acetyl-CoA a 1,2-diacyl- phosphoethanolamine a DNA containing an β-D-glucopyranose -D- ArcAB Two-Component Signal dehydroadipyl- 2,3-dihydroxy- (S)-(+)-allantoin N 7 -methylguanine D-glucopyranose D-fructofuranose PhoQP Two-Component BarA UvrY Two-Component Signal Transduction System BtsSR Two-Component CusSR Two-Component AtoSC Two-Component DpiBA Two-Component BasSR Two-Component PyrSR Two-Component EvgSA Two-Component Signal Transduction System BaeSR Two-Component UhpBA Two Component HprSR Two-Component 2-oxoglycine 6-phosphate cellulose apurinic/apyrimidinic site 1-phosphate galactopyranose Transduction System, quinone dependent KdpDE Two-Component CreCB Two-Component TorTSR Signal Transduction System, TMAO dependent RstBA Two-Component DcuSR Two-Component PhoRB Two-Component CoA hydratase: trans-cinnamate sn-glycerol GatZ CvrA Signal Transduction System, Signal Transduction System Signal Transduction System Signal Transduction System CpxAR Two-Component phosphate allantoinase: Signal Transduction System Signal Transduction System Signal Transduction System, Signal Transduction System Signal Transduction System Signal Transduction System Signal Transduction System Signal Transduction System Signal Transduction System Signal Transduction System, Signal Transduction System, deacetylase: nagA YhjJ LpoA EfeO RclB EcpE AslA paaF 2,3- allB magnesium-dependent potassium-dependent Signal Transduction System sensory histidine C -dicarboxylate-dependent phosphate-dependent D-glucosamine acetyltransferase: UQ + sensory histidine sensory histidine 4 (3S)- BarA BarA-P his302 BarA-P asp718 BarA-P his861 pyruvate Cu spermidine acetoacetate 3+ his721 asp1009 his1137 dihydroxycinnamate (S)-3-hydroxy-(5Z) 2030 2457 RNase E 2+ citrate Fe pyruvate EvgS EvgS-P EvgS-P EvgS-P eutD allantoate a 2-acyl-1-lyso- 3 a 23S rRNA adenine uridine (Z)-2- an aliphatic a (2E)-2- Mg his250 his his265 TorS kinase TorS - his443kinase TorS - asp723 kinase TorS - his850 his276 6-phosphate D-glucopyranose maltopentaose isoprimeverose a nucleoside 2,3- 2+ 2+ KdpD-N-phospho- BaeS BaeS-P UhpB UhpB-P HprS phosphorylated HprS CreC CreC-P RstB RstB-P hydroxyadipyl- dioxygenase: mhpB glycerophosphoglycerol an N -methyladenine in DNA 1911/1915/1917 palmitoleoyl-CoA hydroxypyruvate a quinone degradation L-dopa L-idarate heme b Co Co KdpD his349 his213 phosphatidylethanolamine -dodecenoyl-CoA uridine in 23S rRNA in 23S rRNA methylureidoacrylate α,ω-diamine enoyl-CoA CpxA CpxA-P his248 phosphorylated phosphorylated phosphorylated DcuS DcuS-P PhoR PhoR-P CoA carbamoyl phosphate triphosphate diaminopropanoate Ni 2+ CorA Ni 2+ L-histidine (2Z,4E,7E)-2- oxamate allantoate 3-hydroxyacyl-CoA 23S rRNA 6 substrate mRNA his398 23S rRNA m A2030 23S rRNA ureidoacrylate acyl-CoA FMN dependent diamine trans-2- L-idarate heme d his371 acetyltransferase: pta nucleoside triphosphate 1911/ YjcE 2+ 2+ his292 asp576 his717 AtoS AtoS-P PyrS PyrS-P 3-hydroxyadipyl- hydroxy-6-oxonona- phosphate amidohydrolase: dehydrogenase: fadJ 2,3- pseudouridine 2457 hydroxypyruvate 4,5-DOPA Mg Mg ArcB ArcB-P ArcB-P ArcB-P BtsS-N-phospho- his152 methyltransferase: pseudouridine amidohydrolase: dehydrogenase: NADH:quinone ribonuclease: transaminase: enoyl-CoA epimerase: synthase: FixA OpgG YchO HlyE FlgJ YbiJ his271 his347 BasS BasS-P amylomaltase: isoprimeverose pyrophosphohydrolase: BtsS CusS CusS-P DpiB DpiB-P CoA 2,4,7-triene-1,9-dioate carbamate α allC glycerophosphoglycerol 3 methyl-adenine 3-hydroxyacyl-CoA diaminopropionate 1915/1917 isomerase: hyi dioxygenase 2+ 2+ L-histidine -D-glucosamine acetyl phosphate α rlmJ synthase: rluE rutB fadE reductase,: azoR rne patA reductase gudD katE Mg MgtA Mg dehydrogenase: 2-hydroxy-6- malQ -xylosidase: yicI mazG ammonia-lyase: ygeX 6 extradiol: ygiD kinase: ybcF 6-phosphate acyltransferase: pldB DNA glycosylase: tag dehydrogenase: fadB synthase: rluD an N - 2457 ω (S)-ureidoglycine 1911/ a pseudouridine (Z)-2- (2E,9Z)- tartronate an aliphatic - a 2,3,4-saturated paaH oxononatrienedioate a nucleoside 5'- pyruvate a pseudouridine methyladenine 2030 a semiquinone an mRNA fragment 4,5-seco-dopa D-glucarate heme d his277 carbamoyl glucosamine- acetate 3-oxo-(5Z)-dodecenoyl-CoA in 23S rRNA methylaminoacrylate hexadecenoyl-CoA semialdehyde aminoaldehyde fatty acyl CoA PhoQ PhoQ-P hydrolase: mhpC monophosphate 1915/1917 in 23S rRNA phosphate kinase: purT (S)-ureidoglycine in 23S rRNA YbjL RarD asp53 3-oxoadipyl-CoA 6-phosphate α FliE YbgS YcbF MlaC YgiW YmfQ asp asp52 DcuR-P DcuR PhoB-P PhoB sn-glycero-3- a lyso- a DNA containing an maltose maltotetraose D-glucopyranose -D-xylopyranose BaeR-P asp61 BaeR UhpA-P asp UhpA HprR-P HprR CreB-P asp54 CreB TorR-P TorR RstA-P RstA (2Z)-2-hydroxypenta- synthetase: deaminase: acetate aminohydrolase: 3-methyladenine asp51 asp phosphoethanolamine phosphatidylglycerol apurinic/apyrimidinic site BasR-P BasR KdpE-P asp KdpE PyrR-P asp PyrR EvgA-P EvgA CpxR-P CpxR β-ketoadipyl- 2,4-dienoate Phosphorylated DNA- DpiA-P asp57 DpiA carB carA nagB kinase: ackA allE CusR-P asp51 AtoC-P AtoC binding transcriptional BtsR CusR CoA thiolase: carbamate F6P acetate (S)-ureidoglycolate 32 dTDP-β-L- 955/2504/ 1939 2604 55 RNase G (2E)-2- dual regulator BtsR a 2-methylthiocytosine (S)-3-hydroxy-(9Z) a 5' triphospho- uridine a uracil a uridine succinate a uridine YdgK YfaV asp54 2-oxoglutarate a lipopolysaccharide D-glucopyranose maltohexaose an organic hydroperoxide a C-nitro compound N-ethylmaleimide methylglyoxal L-idonate acryloyl-CoA (R)-NADHX an aldehyde ZinT SfmC YjfN OpgD YjbT YbaE UvrY-P UvrY paaJ rhamnose -hexadecenoyl-CoA 2580 in 23S rRNA in 23S rRNA semialdehyde in tRNA degradation hydroxypenta- ureidoglycolate in tRNA [mRNA] in 23S rRNA EnvZ/OmrR Two-ComponentRcs Signal Transduction System QseBC Two-Component NtrBC Two-Component Regulatory System 3-hydroxyacyl-CoA lipid hydroperoxide NADPH-dependent 23S rRNA 5 substrate mRNA L-idonate 5- 2,4-dienoate asp54 asp51 ZraSR Two-Component GlrKR Two-Component RNA 23S rRNA m U1939 23S rRNA succinate tRNA acrylyl-CoA NADHX ArcA-P ArcA PhoP-P PhoP succinyl-CoA lyase: allA 955/ N-ethylmaleimide methylglyoxal NarX Two-Component Signal NarQ Two-Component Signal Signal Transduction System Signal Transduction System, lipopolysaccharide dehydrogenase: fadJ peroxidase: tpx nitroreductase: nfsA pyrophosphohydrolase: pseudouridine methyltransferase: pseudouridine 2604 semialdehyde pseudouridine 55 ribonuclease: dehydrogenase: tautomerase: reductase: epimerase: Chemotactic Two-Component Signal Transduction Aerotactic Two-Component Signal Transduction System Signal Transduction System Signal Transduction System amylomaltase: reductase: nemA reductase: ydjG Transduction System, nitrate dependent Transduction System, nitrate dependent quorum sensing related 2-methylthiocytosine core rhamnosyl 3-hydroxyacyl-CoA thiol peroxidase: bcp NAD(P)H rppH 2504/2580 rlmD synthase: rluF reductase: yihU synthase: truB rng idnD pptA yhdH nnr his479 asp875 CO glyoxylate NrfE RcsC RcsC-P RcsC-P RcsC his 2 malQ NtrB NtrB-P dethiomethylase: alkB transferase: waaS dehydrogenase: fadB peroxiredoxin: osmC nitroreductase: nfsB synthase: rluC 1939 2604 55 5-dehydro- YbhM YobA YdeP YdbJ YfdX HdeB FimC his243 Inorganic Nutrient Metabolism a 5'-phospho- 955/ a 5-methyluracil a pseudouridine a pseudouridine his254 GlrK GlrK-P his259 EnvZ EnvZ-P RcsD-N-phospho- his246 a hydroxylamino group- a pseudouridine N-ethylsuccinimide 4-hydroxybutanoate hydroxyacetone 2-oxopent- propanoyl-CoA (S)-NADHX a carboxylate his48 his399 his399 ZraS ZraS-P QseC QseC-P an mRNA fragment his48 his48 CheA CheA(L)-P NarX NarX-P NarX NarX-P his370 his370 RcsD 3-oxo-(9Z)-hexadecenoyl-CoA an alcohol [mRNA] in 23S rRNA in 23S rRNA in tRNA D-gluconate CheA CheA(L)-P CheA CheA(L)-P his48 CheA CheA(L)-P NarQ NarQ-P NarQ NarQ-P L-histidine containing compound 2504/2580 in 23S rRNA 4-enoate (aminomethyl)phosphonate degradation 32 a rhamnosyl dTDP superpathway of sulfate assimilation and cysteine biosynthesis methylphosphonate a 2-thiocytosine formaldehyde succinate maltopentaose maltose two-component alkanesulfonate monooxygenase lipopolysaccharide YbhI degradation I in tRNA IbsA CbrA YncE YdeI QseG FlgA NlpE (aminomethyl)phosphonate 3-phospho-D-glycerate sulfate methylphosphonate an alkylsulfonate FMNH asp51 asp NtrC aminomethylphosphonate 2 (heptosyl) - 2605 65 asp59 asp56 asp56 asp56 NtrC-P 2 (S)-3-hydroxy-(7Z) asp asp59 GlrR-P GlrR OmpR-P OmpR P RcsB RcsB QseB-P QseB NtrC α [(R)-1- a [release factor]- an N-hydroxy- uridine a uridine (Z)-3- α-ribazole asp asp CheY-P CheY NarL-P NarL ZraR-P ZraR asp59 asp59 α UDP- -D-glucose L-idonate asp CheB-P CheB CheY-P CheY NarP-P NarP NarL-P NarL NarP-P NarP phosphorylated dimer N-acetyltransferase: phnO sulfate D-3-phosphoglycerate -D-ribose 1- a double stranded DNA Kdo -lipid A 11-deoxycorticosterone 2-hydroxy-dATP cholate spermidine cis-vaccenoyl-CoA a quinone nitric oxide diacetyl glutathione CheY-P CheY 2 aminoethyl]phosphonate -tetradecenoyl-CoA L-glutamine arylamine in 23S rRNA in tRNA ureidoacrylate 5'-phosphate YhjE methylphosphonate (acetamidomethyl)phosphonate adenylyltransferase: dehydrogenase: serA (R)-1- 3-hydroxyacyl-CoA oxidized nucleoside protein-(glutamine-N 5 7-α-hydroxysteroid N-hydroxyarylamine 23S rRNA spermidine N 8 - acyl-CoA tRNA ureidoacrylate NADPH:quinone L-idonate 5- α nitric oxide diacetyl 5-triphosphate 11-deoxycorticosterone -ribazole-5'-P ApaG RcsF YahO RcnB YehC YraI cysD cysN dehydrogenase: fadJ triphosphate 2605 65 dehydrogenase: YidH α lipopolysaccharide aminoethylphosphonate ) methyltransferase: dehydrogenase: O-acetyltransferase: pseudouridine acetyltransferase: dehydrogenase: pseudouridine amidohydrolase: oxidoreductase: phosphatase: dioxygenase: reductase: -D-ribose-1-(2-N- 3-phosphooxypyruvate synthase: phnL DNA exonuclease: recE reductase: kduD pyrophosphohydrolase: idnD glucosyltransferase: N-acetyltransferase: phnO 3-hydroxyacyl-CoA prmC hdhA nhoA synthase: rluB speG fadE synthase: truC rutB qorA cobC hmp ucpA acetamidomethylphosphonate) APS α-D-ribose-1-phnH phnG phnI 5' to 3' exonuclease: polA nudG waaG [(1R)-1- dehydrogenase: fadB 4-pregnen- a [release factor]-N 5 3α,12α-dihydroxy-7- a pseudouridine 2605 N 8 - (2E,11Z)- a pseudouridine 65 (Z)-3- 5-dehydro- -5-triphosphate synthase: 3-phosphoserine an N- a semiquinone nitrate (S)-acetoin GSSG YcfJ methylphosphonate- 3-oxo-(7Z)-tetradecenoyl-CoA 2-hydroxy-dAMP β D-gluconate α-ribazole adenylyl-sulfate alkanesulfonate FMN acetamidoethyl]phosphonate 20,21-diol-3-one -methyl-L-glutamine oxo-5 -cholan-24-oate acetoxyarylamine in 23S rRNA acetylspermidine octadecenoyl-CoA in tRNA aminoacrylate phnL phnH phnG phnI aminotransferase: serC 5-triphosphate OsmY NapF DcrB CpoB YcbX MalM α-D-ribose 1- kinase: cysC glucosyl-(heptosyl) α-D-ribose-1- monooxygenase: reductase: UDP YdhU (acetamidomethylphosphonate) a 5'-phosphomononucleotide a single stranded DNA -Kdo -lipid A O-phospho-L-serine methylphosphonate- ssuD ssuE 2 2 5-triphosphate PAPS FepE 5-triphosphate α -D-ribose-1-(2-N- diphosphatase: phnM phosphoadenosine phosphoserine α-Kdo-(2->4)-α-Kdo- 967 747 13 acetamidomethylphosphonate) α-D-ribose-1- glycerol an L-1- CMP-Kdo [(S)-1- a cytosine a uracil (3R)-3,4- a uridine glycolaldehyde β-D-fructofuranose glycerol 1- D-galactono- Asr LolA YmgD YebF YdhX PqiC phosphosulfate phosphatase: serB (2->6)-lipid IV (E. coli) 3-hydroxypropanal glutathione hydroquinone uroporphyrinogen-III (R)-pantolactone spermidine putrescine 8-oxo-GDP nigerose YtfB -5-triphosphate phosphatidylethanolamine A aminoethyl]phosphonate in 16S rRNA in 23S rRNA dihydroxybutanal in tRNA phosphate 1,4-lactone reductase: cysH methylphosphonate thiosulfate disproportionation (S)-1- S-adenosyl-L- hydroquinone:hydrogen uroporphyrinogen-III 16S rRNA m 5 C967 23S rRNA m 5 U747 spermidine N 1 - D-3,4- tRNA putrescine 8-oxo-GDP D- diphosphatase: phnM 5-phosphate IV (rhodanese) 3-hydroxypropionaldehyde 2-dehydropantoyl- glycolaldehyde fructokinase: glycerol-3- YibH α-D-ribose-1-(2-N- 13 sulfite ser carbon- aminoethylphosphonate methionine:glutathione peroxide C-methyltransferase: methyltransferase: methyltransferase: acetyltransferase: dihydroxybutanal pseudouridine reductase: yqhD aminotransferase: mak diphosphatase: phosphatase: galactono- phosphatidylglycerol Kdo transferase: dehydrogenase: puuC lactone reductase acetamidomethylphosphonate) phosphorous N-acetyltransferase: phnO methyltransferase: cheR oxidoreductase: ccp cysG rsmB rlmC speG reductase: yqhD synthase: truD patA mutT hxpA γ-lactonase an aldehyde FMN thiosulfate synthase: clsB waaZ IaaA PliG YfcS YbgP YceI YfaL 5-phosphate assimilatory serine lyase: phnJ [(1S)-1- a 5-methylcytosine 967 a 5-methyluracil 747 N 1 - a pseudouridine 13 α 3-hydroxypropanoate S-methylglutathione 1,4-benzoquinone precorrin-2 2-dehydropantolactone 1,3,4-butanetriol ethylene glycol 1-pyrroline F6P 8-oxo-GMP glycerol D-galactonate D-glucopyranose YaiY carbon-phosphorous sulfite reductase acetyltransferase: cysE 5-phospho- - acetamidoethyl]phosphonate in 16S rRNA in 23S rRNA acetylspermidine in tRNA D-ribose 1,2- thiosulfate- α α YsaB lyase: phnJ (NADPH): cysJ cysI an L-1-phosphatidyl- CMP -Kdo-(2->4)- -Kdo-(2-> cyclic phosphate ammonia assimilation cycle III sulfurtransferase: ygaP ethanolamine 4)-α-Kdo-(2->6)-lipid IV α O-acetyl-L-serine sn-glycerol A 5-phospho- -D-ribose hydrogen sulfide 5-phospho-α-D-ribosyl YfiR FtsP SecM YjfY YggM thiosulfate L-glutamine Ais 1,2-cyclic phosphate 1,2-cyclic phosphate cyanate degradation sulfurtransferase: sseA glutaminase: asnB 6 gln ABC gln α an N -L- 1407 34 α 32 5-fluorouridine 5'- aldehydo- YicL 5-phospho- -D-ribosyl phosphodiesterase: gln glutaminase: glsA thiosulfate UDP-Galf a 5,10- 3-(3,4-dihydroxyphenyl) a [ribosomal protein a cytosine glucosyl-(heptosyl) a cytidine in 2,6- N-acetyl- - a uridine thymine O-acetylserine octyl α-D-glucopyranoside 37 3-phosphooxypyruvate 5,6-dihydrouracil acetaldehyde 8-oxo-GTP D-glucosamine transporter 1,2-cyclic phosphate phnP threonylcarbamoyladenine -Kdo -lipid A met neuraminate monophosphate D-mannose sulfhydrylase: cysM glutaminase: glsB CO sulfurtransferase: glpE methenyltetrahydrofolate pyruvate L3]-L-glutamine in 16S rRNA 2 2 [elongator tRNA ] dimethoxyphenol in tRNA thymine 2 5-fluorouridine phosphodiesterase: phnP carbonic in tRNA 5,10- protein-glutamine N- 16S rRNA m 5 C1407 lipopolysaccharide tRNA Met cytidine dihydropyrimidine tRNA acetaldehyde 8-oxo-GTP- mannose taurine ABC O-acetylserine α-D-ribose 1,5- imidazole glycerol β tRNA N-acetylneuraminate oxygenase: glucosamine -1,6- 3-phosphohydroxypyruvate hydroxyphenyllactate 32 5'-nucleotidase: isomerase: taurine taurine Ivy HdeA FlhE YdeN YhcA PqqL anhydrase: methenyltetrahydrofolate methyltransferase: methyltransferase: core heptose acetyltransferase: dehydrogenase: pseudouridine dehydrogenase: rutA diphosphatase: transporter α sulfhydrylase: cysK bisphosphate phosphate thiocyanate sulfite galactofuranosyltransferase: wbbI threonylcarbamoyladenosine phosphatase: nudL dehydrogenase: hcxB mutarotase: nanM yjjG kinase: glk -D-ribose 1,5-bisphosphate cynT hydrolase: glyA prmB rsmF (I) kinase: waaP tmcA preT preA synthase: rluA aldB mutT yihS YphA synthase: hisH hisF dehydratase: tcdA β 6 1407 glucosyl-(heptosyl) - 4 34 N-acetyl- - 32 (Z)-2- D-glucosamine a cyclic N -L- a (6S)-5- (R)-3-(3,4- a [ribosomal protein L3]- a 5-methylcytosine 2 an N -acetylcytidine 3,3',5,5'- uracil a pseudouridine 5-fluorouridine keto-D-fructose a dipeptide DtpD a dipeptide ribose 1,5-bisphosphate xanthosine-5'- hydroxypyruvate 5 Kdo -lipid A-phosphate met neuraminate acetate methylureidoacrylate 8-oxo-GMP 6-phosphate cys octyl β-1,6-D-galactofuranosyl- threonylcarbamoyladenosine formyltetrahydrofolate dihydroxyphenyl)lactate N -methyl-L-glutamine in 16S rRNA 2 in [elongator tRNA ] tetramethoxydiphenoquinone in tRNA phosphokinase: phnN phosphate:L-glutamine UDP α-D-glucopyranoside 37 in tRNA YhcN YadV Ggt YtfJ DolP DigH glutamine amido-ligase (AMP- carbamate hydrogencarbonate glutamate / YhhN PRPP synthetase: glnA forming): guaA asp aspartate asp [+ 3 isozymes] a 5-carboxymethylaminomethyluridine 34 a double β-D-glucopyranose 1962 CTP N-acetyl-α- 5,6- a uridine 35 a (1->4)- adenine a 5-(methoxycarbonylmethoxy) a single an insertion sequence a cytosine a β-D-galactoside D-mannopyranose α-lactose xylan glu ABC glu glu ammonium Leu 34 tellurite dihydrothymine L-rhamnonate oxalyl-CoA α in tRNA uridine in tRNA stranded DNA stranded DNA 1-phosphate element IS30 in 23S rRNA nucleoside triphosphate neuraminate in tRNA -D-glucan transporter phosphoribosyltransferase: apt taurine degradation IV dihydropyrimidine tRNA (5- tRNA (5- single stranded transposase: insI3 23S rRNA m 5 C1962 tellurite 2,7-anhydro-N- galactoside O- tRNA Tyr L-rhamnonate oxalyl-CoA xylan α- SgrR CsgC YbcL MarB OmpA AaeX cyanase: cynS exodeoxyribonuclease β-phosphoglucomutase: pyrophosphohydrolase: mannokinase: β-galactosidase: α-amylase: molybdate molybdate acetylneuraminate acetyltransferase: dehydrogenase: 35 xylosidase: CO carboxymethylaminomethyluridine) methoxycarbonylmethoxyuridine) endodeoxyribonuclease: transposase: insI2 methyltransferase: mazG methyltransferase: pseudouridine dehydratase: mak lacZ decarboxylase: amyA thiosulfate/ diphosphate 2 V: recD recC recB ycjU preT preA sulfate sulfate taurine cyanate -ribose methyltransferase: trmL -ribose methyltransferase: trmL recD recC recB transposase: insI1 rlmI tehB hydratase: nanY lacA synthase: rluF rhmD oxc yicI sulfate ABC α-ketoglutarate- CMP 2,7-anhydro-α-N- a 6-acetyl-β- thymine a (1->4)- thiosulfate thiosulfate 4,6-pyr- a 5-carboxymethylaminomethyl- a 5-(methoxycarbonylmethoxy) β-D-glucose an insertion sequence IS30 a 5-methylcytosine 1962 a pseudouridine 35 2-dehydro-3-deoxy- D-mannopyranose α transporter diphosphate a 5'-phosphooligonucleotide a 5'-phosphooligonucleotide methanetelluronate allolactose formyl-CoA -D-xylopyranose α [+ 2 more] [+ 2 more] α-D-Gal- dependent taurine 34 Leu 34 acetylneuraminate D-galactoside L-rhamnonate 6-phosphate -D-glucan phosphatase: phoA 2'-O-methyluridine in tRNA -2'-O-methyluridine in tRNA 6-phosphate with integrated transposon in 23S rRNA in tRNA YqjE (1->4)-β- dioxygenase: tauD L-glutamate:NADP+ inorganic D-GlcA- 2-aminoacetaldehyde oxidoreductase pyrophosphatase: ppa molybdate sulfate/ molybdate (1->3)-2- (deaminating): gltB gltD sulfate thiosulfate sulfate α O-Ac- -D- phosphate glutamate thiosulfate ABC thiosulfate Alx 4-amino-4- Gal-(1->3) D-glucopyranose 6-phosphate dehydrogenase: gdhA [+ 2 more] transporter [+ 2 more] α -α-L-Fuc- deoxy- -L- 1,6- D-mannopyranose 6-phosphate L,L-homocystine a ferric (1->4)-3- iron(III)- arabinopyranosyl L,L-homocystine anhydro- magnesium hydrogenphosphate magnesium hydrogenphosphate D-fructofuranose 6-phosphate phosphate N-acetyl-D- 3-O-β-D-galactopyranosyl-D-arabinose D-cystine putrescine hydroxamate O-Ac-α-L- an aliphatic D-mannitol enterobactin an + ditrans,octacis D-fructose β nalidixate L-glyceraldehyde 3-phosphate a glycerophosphodiester D-sorbitol 6-phosphate D-sorbitol galactitol 1- deoxycholate an Ag spermidine D-cystine sulfonate γ-butyrobetaine N-acetyl- - putrescine phosphate calcium hydrogenphosphate calcium hydrogenphosphate 4-aminobutanoate 1-phosphate cadaverine a lyso-cardiolipin muramate 6- oligopeptide a dipeptide melibionate lanthionine complex Fuc-(1->3) α-D-galactofuranose L-arabinose 6 complex + + nalidixate -undecaprenyl sn-glycerol asp phosphate K oligopeptide lipid II (meso L-homoserine lactone Cu L-lyxopyranose 1-phosphate D-ribopyranose D-glucuronate L-cystine cefoperazone an (aminoalkyl)phosphonate asn GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala muramate 3-(3-hydroxyphenyl)propanoate carbonylcyanide m-chlorophenylhydrazone deoxycholate arsenate zinc hydrogenphosphate phosphate sn-glycerol 3-phosphate glu glu D-mannitol 1-phosphate D-sorbitol 6-phosphate 6-phosphate lys lys D-serine a quaternary ammonium compound pro ser ser trp a 2-acyl-1-lyso-phosphatidylethanolamine N-acetyl-β- 6-sulfo-D- phosphate N -(D-psicosyl)-L-lysine 5-aminopentanoate a D- a peptide 2,7-anhydro-α-N- oleoyl-CoA oleoyl-CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a tripeptide lactulose a tripeptide a tripeptide shikimate L-homoserine acetoacetate α β an amino preQ L-carnitine 3-phenylpropanoate ammonium putrescine putrescine putrescine sulfate cyanate cadaverine + [+ 3 more] spermidine phosphate - -D-Glc- -D-galactofuranose cetylpyridinium deoxycholate 0 non-specific non-specific non-specific L-arabinose a drug 3-phosphate glu FAD 6 diaminopimelate L-homoserine + lys an alkylphosphonate β β 3-hydroxycinnamate deoxycholate D-mannitol 1-phosphate pro quinovose N -(D-fructosyl)-L-lysine 4-aminobutanoate glucoronoside a lipid A-core antibiotic Na acetylneuraminate palmitoleoyl-CoA palmitoleoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA a dipeptide [+ 2 more] a dipeptide a dipeptide Cu enterobactin L-rhamnose D-galacturonate fosmidomycin S-sulfo-L-cysteine chloramphenicol N-acetyl- -D-glucosamine-1,6-anhydro-N-acetyl- -D-muramate L-arabinose phosphate [+ 3 more] phosphate a lyso-phosphatidylglycerol neuraminate α-lactose α-lactose containing) thr thr PP-Und guanidinium fosfomycin acid ion/solute ion/solute ion/solute carbonylcyanide m-chlorophenylhydrazone FMN oligosaccharide [+ 2 more] copper/ spermidine iron(III) aliphatic mannitol- ferric putative multidrug/ undecaprenyl- fructose- ABC N-acetylmuramic multidrug tripartite arabinose putrescine phosphate sn-glycerol 3-phosphate sorbitol- galactitol- N-acetylmuramic galactitol- oligopeptide dipeptide cystine ABC silver preferential hydroxamate ribose ABC galactofuranose sulfonate specific enterobactin oligopeptide YfbV HdeD LdrA YbaV RseA ShiA MurJ PppA CbrB HofC FliL YebO RhtB RhtA CopA ProY spermidine LysO AtoE phosphate-α-L- EntS RhaT WzxC specific PTS ExuT Fsr TcyP Gdx MdtG exporter MdtL YddG PhnCDE AnsP YhhQ CaiT AmpG acid-specific HcaT MhpT MscS MscL MscK efflux pump efflux pump ABC YdeA AraE EmrD AmtB PlaP PuuP ABC PotE ABC PitB PitA UhpT YjbB CysZ / glycerophosphodiester GlpT GltP GadC GltS YqeG specific PTS MtlA specific PTS CadB LysP DsdX PPIII PutP SstT SdaC TnaB CynX YeeO LplT NanT YihO acid-specific specific PTS FrlA GabP CadB UidB MsbA SbmA YadS YbfA YmfR YohC MdtM YebQ PsiE YqiJ NanX FadK FadD FadD FadK ABC ABC DtpC LacY SetA SetB DtpA DtpB transporter export ABC ABC transporter ABC transporter ABC PTS enzyme ABC ABC efflux pump Ara4N flippase enzyme II YbhFSR PTS enzyme II EmrAB-TolC EmrKY-TolC transporter transporter transporter ABC transporter enzyme II enzyme II PTS enzyme II enzyme II transporter transporter system transporter transporter transporter II CmtBA transporter transporter γ β α L-lyxopyranose D-glucuronate L,L-homocystine an (aminoalkyl)phosphonate GlcNAc-1,6-anhMurNAc-L-Ala- -D-Glu-DAP-D-Ala 3-(3-hydroxyphenyl)propanoate magnesium hydrogenphosphate magnesium hydrogenphosphate D-sorbitol a quaternary ammonium compound a lyso-cardiolipin N-acetyl- - 6-sulfo-D- N 6 -(D-psicosyl)-L-lysine 5-aminopentanoate a D- a peptide 2,7-anhydro- -N- oleate oleate a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a tripeptide 3-O-β-D-galactopyranosyl-D-arabinose a tripeptide a tripeptide shikimate L,L-homocystine acetoacetate α-D-galactofuranose preQ 3-phenylpropanoate L-arabinose ammonium putrescine putrescine putrescine sulfate asp cyanate cadaverine lipid II (meso L-homoserine lactone L-rhamnose D-galacturonate 0 N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate D-mannitol neuraminate quinovose 6 glucoronoside a lipid A-core deoxycholate acetylneuraminate + 4,6-pyr- D-ribopyranose D-cystine β cetylpyridinium deoxycholate an alkylphosphonate asn 1,6- 3-hydroxycinnamate non-specific non-specific non-specific L-arabinose a drug calcium hydrogenphosphate calcium hydrogenphosphate a glycerophosphodiester sn-glycerol glu D-sorbitol lys D-serine pro pro ser ser trp FAD a 2-acyl-1-lyso-phosphatidylethanolamine N-acetyl-D- N -(D-fructosyl)-L-lysine 4-aminobutanoate antibiotic palmitoleate palmitoleate cis-vaccenate cis-vaccenate an a dipeptide melibionate α-lactose α-lactose a dipeptide a dipeptide L-homoserine Cu enterobactin fosmidomycin -D-galactofuranose chloramphenicol an amino L-carnitine galactitol + diaminopimelate D-cystine L-homoserine putrescine lys a ferric D-fructose an aliphatic L-arabinose putrescine phosphate phosphate phosphate glu glu D-sorbitol lys iron(III)- oligosaccharide K an a dipeptide thr nalidixate 4-amino-4- α-D-Gal- L-cystine guanidinium fosfomycin acid anhydro- ion/solute ion/solute ion/solute carbonylcyanide m-chlorophenylhydrazone arsenate zinc hydrogenphosphate sn-glycerol 3-phosphate 3-phosphate D-mannitol D-mannitol FMN a lyso-phosphatidylglycerol muramate oligopeptide lactulose lanthionine hydroxamate cefoperazone γ 4-aminobutanoate cadaverine enterobactin + containing) thr spermidine spermidine deoxy-α-L- (1->4)-β- S-sulfo-L-cysteine sulfonate -butyrobetaine N-acetyl-β- phosphate [+ 3 more] D-glucopyranose 6-phosphate Na oligopeptide [+ 2 more] [+ 3 more] complex complex arabinopyranosyl D-GlcA- muramate D-mannopyranose 6-phosphate phosphate [+ 2 more] ditrans,octacis (1->3)-2- D-fructofuranose 6-phosphate Ag + -undecaprenyl α nalidixate L-glyceraldehyde 3-phosphate O-Ac- -D- deoxycholate Cu + phosphate Gal-(1->3) carbonylcyanide m-chlorophenylhydrazone -α-L-Fuc- deoxycholate (1->4)-3- O-Ac-α-L- Fuc-(1->3) -α-D-Glc- PP-Und Copyright SRI International 1999-2021, Marine Biological Laboratory 1998-2001, DoubleTwist Inc 1998-1999. All Rights Reserved. This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.