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SAN DEIGO 2001 INSAR 2021 VIRTUAL BOSTON 2005 TH ANNIVERS 20 ARY LONDON 2008 2001 2021 CHICAGO 2009 MAY 3-7, 2021 SAN SEBASTIAN 2013 www.autism-insar.org SAN FRANCISCO 2017 On-Demand Content Available to Registrants Until June 7, 2021 MONTREAL 2019 2021 SPONSORS We thank the following organizations for their generous support of INSAR and the Annual Meeting. Platinum Silver Hilibrand Foundation Nancy Lurie Marks Family Foundation Bronze Autism Science Foundation Roche TABLE OF CONTENTS Sponsorship .........................................................................1 Meeting Chair Welcome ....................................................... 2 Scientific Program Chairs’ Welcome .................................... 3 President’s Welcome Letter ..............................................4-5 Meeting Information INSAR Meeting Celebrating 20 Years ................................ 6-7 Schedule at a Glance ...................................................... 8-10 In-Conjunction Events ....................................................11-13 Keynote Speakers ...............................................................14 2021 INSAR Fellows ............................................................15 Follow us on Twitter: 2021 and 2020 Awardees ............................................... 16-19 @AutismINSAR Acknowledgements .......................................................20-21 Join the conversation: INSAR Institute 2021 .......................................................... 22 #AutismINSAR #INSAR2021 General Information ...................................................... 23-25 2021 Exhibitors .................................................................. 26 https://www.facebook.com/ Save the Date 2022............................................................ 27 AutismINSAR Autism Research Journal Information ................................ 28 INSAR Strategic Initiatives ................................................ 29 Follow on Instagram @autism.insar MONDAY Events ............................................................................... 30 MAY 3 Special Interest Groups (SIGs)............................................ 30 TUESDAY President Address ..............................................................31 MAY 4 Keynote Address ................................................................31 Oral Sessions .................................................................31-38 Panels Sessions ............................................................38-41 Keynote Address ................................................................ 41 Awards Ceremony............................................................... 41 WEDNESDAY Keynote Addresses .................................................... 42 & 46 MAY 5 Panels Sessions ............................................................42-51 Events ............................................................................... 46 Oral Sessions ................................................................. 51-57 THURSDAY Events ........................................................................58 & 67 MAY 6 Keynote Address ............................................................... 62 Panels Sessions ........................................................... 58-66 Special Interest Groups (SIGs)....................................... 66-67 FRIDAY Events ............................................................................... 68 MAY 7 E-Posters Index ................................................................. 69 ON DEMAND E-Posters ....................................................................70-144 AUTHORS Author Index ..............................................................145-208 1 INSAR WELCOME What a year for us all. I very much wish that I could be welcoming you in person to my beautiful city of Boston for the INSAR annual meeting of 2021. But of course we will have to settle for seeing each other in small boxes on a screen. However, this in no way lessens the importance and impact of the incredible science that will be presented in our virtual meeting this year. The program committee did an amazing job reviewing over 1,300 abstracts and panel submissions from all over the world and covering research areas as diverse as the neurodevelopment spectrum we study. We will be seeing exciting keynote addresses from across the globe and hearing from Boston’s own INSAR Lifetime Achievement award winner Helen Tager-Flusberg. It has been my privilege to work with the INSAR Board over the course of the year to plan this important 20th anniversary meeting. I, like a small group of you, was at that first meeting in San Diego and feel so fortunate to see all the growth and amazing work the society has done over the past 20 years. I am so grateful for the support of the board and the staff at INSAR as well as our meeting planners at Conference Direct in making this year a success. The pivot to virtual was not an easy one but I hope you agree that it will be successful and a meeting not to be missed. While I am truly disappointed you will not be walking the streets of Boston, spending time in our public spaces, browsing in our shops, visiting our museums, and experiencing our wonderful eateries there is something to be said for the virtual meeting experience. We fully anticipate that there are researchers who will be able to attend with this format who might not have been able to do so otherwise. And now that we are all so good at managing our meetings via screens that translates into more opportunities for sharing ideas and forming future collaborations. In addition to the great science, you will be seeing we have a virtual INSAR 5K for those of you athletically inclined. Again, it won’t be through the streets of Boston (that were originally laid out for horse and carriage) but you can pick your favorite local route and benefit a wonderful program called the COLOR of AUTISM. The local New England Autism Community will also benefit this year. As Meeting Chair, I am organizing a stakeholder conference with my friend and colleague Ann Neumeyer where this vibrant group can get a glimpse of this meeting by hearing from some of our keynotes and our lifetime achievement award winner. We have also gathered local speakers to discuss the impact of COVID 19 on our community over the past 14 months. A very special thanks to INSAR for supporting these important meetings to engage key stakeholders and community members. I very much hope you enjoy the meeting as much as I plan to. And please come visit Boston when circumstances allow. You will not be disappointed. Very Sincerely, Sarah Spence, MD, PhD INSAR 2021 Meeting Chair INSAR 2021 is the Annual Meeting of the International Society for Autism Research (INSAR). 2 SCIENTIFIC PROGRAM Welcome to the 20th International Society for Autism Research (INSAR) Annual Meeting. As your scientific program and executive committee co-chairs, we wish we could see you in person in Boston, but thrilled to meet you virtually, given the unprecedented year of challenges related to the COVID-19 pandemic. The pandemic profoundly affected our lives over the past year. We offer condolences to those who lost loved ones. We acknowledge the enormous global economic burden resulting from the pandemic itself and the emergency measures developed to contain it. Emerging evidence suggests that individuals with autism and their families are experiencing disproportionate burden from both the virus itself and the emergency measures. The pandemic also unmasked inequities around the globe and their effects on those with disabilities, from access to critical health care, to prioritization for vaccination, to planning for dealing with the aftermath of the pandemic. Autism research was also significantly impacted. Labs around the world were shut down during much of the pandemic, our ability to measure meaningful outcomes was challenged, and novel discoveries were delayed. Still, our communities remained engaged in scientific discovery and technological innovation that facilitated not only research during this period but may also change the face of autism research in the future. COVID-19 pandemic taught investigators important lessons about new forms of sharing and collaboration, further highlighted the role of creativity and flexibility, which we hope will be illustrated at this meeting. The more than 1300 accepted abstracts reflect such scientific progress and innovation from around the world this year. They represent research in 6 continents / 44 countries, are led by investigators at all stages of career development, and span neuroscience, psychology, medicine, clinical innovation, lived experience, international /global perspectives among many disciplines. Our keynote speakers, Petrus De Vries, Tony Charman, Lucina Uddin and Stormy Chamberlain will offer additional insights to global health and autism, diagnosis and developmental trajectories, brain development in autism and across neurodevelopmental conditions, and rare genetic disorders associated with autism and the potential of novel interventions. We are grateful to the members of the INSAR Board, Executive and Scientific Program Committees, Jennifer Gentry, INSAR Administrative Director, and Joe Dymek, our conference manager, for their dedication, commitment, and hard work, as we converted the meeting and all procedures leading up to it into virtual ones. We also would like to thank all our presenters for the cooperation and flexibility
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