Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_007970805Cyc: Flavisolibacter ginsenosidimutans Gsoil 636 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari

fluoride phosphate D-ribose arsenite ethanolamine a dipeptide

CrcB RbsC ArsB Eat RS18440 RS05465

fluoride phosphate D-ribose arsenite ethanolamine a dipeptide

ditrans,octacis- a peptidoglycan with a peptidoglycan dimer (meso ditrans,octacis- lipid II (meso UDP-N-acetyl- (4R)-4-hydroxy- a [protein]- a [protein]-L- a lipid II an L-asparaginyl- an L-cysteinyl- undecaprenyldiphospho- (L-alanyl-γ-D-glutamyl- -diaminopimelate containing) undecaprenyldiphospho- diaminopimelate α-D-muramoyl- 2-oxoglutarate L-tyrosine methionine [tRNA Asn ] [tRNA Cys ] TCA cycle TCA cycle I (prokaryotic) N-acetyl-(N-acetyl-β-D- L-lysyl-D-alanyl-D- N-acetyl-(N- containing) L-alanyl-γ-D- polysaccharide peptide- Metabolic Regulator Biosynthesis inosine 5'-phosphate Nucleoside and Nucleotide Degradation gln Aminoacyl-tRNA Charging guanosine nucleotides alanine) pentapeptide biosynthesis methionine glutaminyl-tRNA biosynthesis via transamidation degradation glucosaminyl)muramoyl- D-alanyl-D-alanine acetylglucosaminyl) glutamyl-meso-2,6- D-alanyl-D-alanine degradation III γ γ bifunctional tyrosine (S)-S-oxide acetyl-CoA L-alanyl- -D-glutamyl-L- carboxypeptidase/ muramoyl-L-alanyl- - peptidoglycan diaminopimeloyl- carboxypeptidase/ aminoacyl- aminoacyl- trehalose biosynthesis I β 4-hydroxy-2- autokinase: reductase lysyl-D-alanyl-D-alanine D-alanyl-D-alanine- D-isoglutaminyl-N-( - synthetase: D-alanyl-D-alanine D-alanyl-D-alanine- tRNA tRNA glu trehalose trehalose IMP oxoglutarate FSB75_RS02685 MsrA: msrA GMP endopeptidase: dacB D-asparaginyl)-L-lysyl- FSB75_RS05360 endopeptidase: dacB hydrolase: hydrolase: D-glucopyranose biosynthesis V biosynthesis IV oxaloacetate IMP aldolase/2- UDP-α-D-glucose monofunctional D-alanyl-D-alanine arfB arfB polysaccharide peptide- 6-phosphate citrate (Si)-synthase, dehydrogenase: bifunctional UTP and CTP dephosphorylation I penicillin-binding monofunctional D-alanyl-D-alanine penicillin- dehydro-3-deoxy- a glycogen biosynthesis methionine α-maltose eukaryotic: guaB metallophosphatase/ biosynthetic protein 2: mrdA biosynthetic carboxypeptidase/ binding phosphogluconate aminoacyl-tRNA aminoacyl-tRNA glycogen peptidoglycan tyrosine (S)-S-oxide bifunctional maltose alpha-D- FSB75_RS02310 XMP 5'-nucleotidase: UTP monofunctional peptidoglycan D-alanyl-D-alanine- protein aldolase: hydrolase: hydrolase: debranching transglycosylase: autokinase: reductase an L-glutamyl- alpha,alpha- glucosyltransferase: FSB75_RS15255 a peptidoglycan with biosynthetic transglycosylase: endopeptidase: dacB 2: mrdA FSB75_RS00210 FSB75_RS13450 FSB75_RS13450 Gln protein malate mtgA FSB75_RS11480 MsrA: msrA gln [tRNA ] trehalose- treS bifunctional 5'/3'-nucleotidase CTP synthase: D,D cross-links (meso- D-ala peptidoglycan mtgA penicillin- a [protein]- a protein-L- GlgX: glgX α α dehydrogenase: mdh , -trehalose SurE: surE FSB75_RS21390 diaminopimelate containing) transglycosylase: binding L-tyrosine methionine- Asp-tRNA(Asn) phosphate a maltodextrin metallophosphatase/ a N- Asp-tRNA(Asn) guanosine di-trans,octa-cis mtgA Asn a tRNA Cys /Glu-tRNA(Gln) synthase (UDP- (S)-malate citrate 5'-nucleotidase: UDP a peptidoglycan with lipid II (meso di-trans,octa-cis protein D-ala acetylglucosamine- glyoxylate pyruvate asn tRNA cys phosphate (S)-S-oxide /Glu-tRNA(Gln) γ -undecaprenyl amidotransferase forming)/trehalose- malto- FSB75_RS15255 CTP (L-alanyl- -D-glutamyl- diaminopimelate -undecaprenyl 2: mrdA -N-acetylmuramyl- amidotransferase purine-nucleoside diphosphate subunit GatC: gatC phosphatase: oligosyltrehalose 5'/3'-nucleotidase L-lysyl-D-alanyl-D- a peptidoglycan di-trans,octa-cis containing) diphosphate (tetrapeptide) subunit GatC: gatC synthase: treY phosphorylase: alanine) pentapeptide dimer (E. faeciums) -undecaprenyl [+ 2 isozymes] FSB75_RS03915 SurE: surE UDP-N- pyrophosphoryl- [+ 13 isozymes] aconitate hydratase: FSB75_RS20255 UMP diphosphate undecaprenol a 5-phosphooxy- a maltooligosyl- CDP D-ala acetylmuramoyl- α,α-trehalose FSB75_RS04100 ammonium L-glutamyl- trehalose class II fumarate xanthosine bifunctional L-alanyl-γ-D- Gln guanine [tRNA ] 6-phosphate malto- hydratase: fumC metallophosphatase/ glutamyl-meso-2,6- bifunctional oligosyltrehalose fumarate cis-aconitate purine-nucleoside 5'-nucleotidase: diaminopimeloyl- Asp-tRNA(Asn) D-alanine alpha,alpha- trehalohydrolase: aconitate hydratase: phosphorylase: CMP FSB75_RS15255 /Glu-tRNA(Gln) succinate trehalose- treZ FSB75_RS04100 FSB75_RS20255 bifunctional 5'/3'-nucleotidase amidotransferase dehydrogenase/ ω phosphate metallophosphatase/ SurE: surE a peptidoglycan ditrans,octacis- Nα,Nε-diacetyl-lysyl- a [bis(guanylyl β-D-fructofuranose 6-O-trans- an N -(1- D-sedoheptulose subunit GatC: gatC α,α-trehalose fumarate reductase xanthine xanthine UDP-N-acetyl-α-D-muramoyl- D-alanyl-D-alanine synthase (UDP- methoxy-mycolyl- sec 5'-nucleotidase: uridine L-alanyl-γ-D-glutamyl-L-lysine dimer (E. faeciums) undecaprenyldiphospho- D-alanyl-D-alanine molybdopterin) cys 1-phosphate hydroxy-2- 1-phosphate ATP roseoflavin ser a tRNA [+ 2 isozymes] tRNA charging forming)/trehalose- iron-sulfur subunit: trehalose 6- FSB75_RS15255 N-acetyl-(N- cofactor oxopropyl) 5'-phosphate phosphatase: FSB75_RS01585 phosphate 5'/3'-nucleotidase D-alanyl-D-alanine acetylglucosaminyl) chaperone]- bifunctional -[protein]- an L-glutaminyl- FSB75_RS03915 succinate D-threo-isocitrate bifunctional UDP-N- muramoyl-L-alanyl- D-alanyl-D-alanine L-cysteine class I fructose- L-arginine class I fructose- Phe SurE: surE carboxypeptidase/ alpha,alpha- serine- [tRNA Gln ] phe a tRNA isocitrate acetylmuramoyl-tripeptide:D- γ carboxypeptidase/ bisphosphate bisphosphate bifunctional α α urate urate D-alanyl-D-alanine- -D-isoglutaminyl- trehalose- -tRNA , -trehalose ADP-forming dehydrogenase cytidine alanyl-D-alanine ligase/ β D-alanyl-D-alanine- aldolase: aldolase: endopeptidase: dacB N-( -D-asparaginyl) phosphate DJ-1/PfpI/YhbO riboflavin kinase/ ligase: succinate--CoA ligase (NADP(+)): alanine racemase: endopeptidase: dacB IscS subfamily FSB75_RS00915 FSB75_RS00915 -L-lysyl-D-alanine synthase (UDP- family deglycase/ FAD synthetase: serS Gln phenylalanine- FSB75_RS11860 penicillin-binding cysteine gln a tRNA subunit beta: sucC FSB75_RS06195 penicillin- class II fructose- forming)/trehalose- class II fructose- FSB75_RS06735 -tRNA ligase protein 2: mrdA desulfurase: protease: ser a tRNA ser a tRNA Ala ala tRNA asp asp succinate--CoA ligase UDP-N-acetylmuramoyl- binding bisphosphate phosphatase: bisphosphate elongator subunit monofunctional FSB75_RS11880 FSB75_RS17980 arg a tRNA Arg val a tRNA Val thr a tRNA Thr met initiator tRNA Met met pro a tRNA Pro trp a tRNA Trp his a tRNA His glu a tRNA glu cys a tRNA Cys lys a tRNA Lys asn tRNA Asn leu a tRNA Leu ile a tRNA Ile gly a tRNA Gly tyr a tRNA Tyr subunit alpha: sucD thymine degradation purine ribonucleosides degradation tripeptide--D-alanyl- protein aldolase: fbaA trehalose- FSB75_RS03915 aldolase: fbaA roseoflavin an L-seryl- tRNA Met alpha: pheS biosynthetic glutamine-- D- alanine ligase: a peptidoglycan tetramer 2: mrdA cysteine [tRNA sec ] succinyl-CoA 2-oxoglutarate peptidoglycan trans-methoxy- adenine tRNA ligase/ serine- phenylalanine- alanine- aspartate- thymine FSB75_RS18925 with a D,D cross-link D-ala desulfurase: a [protein]- transglycosylase: mono-mycolate (R)-lactate dinucleotide arginine-- valine-- threonine- methionine- methionine- proline-- YqeY domain tryptophan- histidine-- glutamate-- cysteine-- lysine- asparagine- leucine-- -tRNA -tRNA ligase isoleucine-- -tRNA glycine-- -tRNA tyrosine-- dihydrothymine adenosine (Enterococcus faecium) FSB75_RS19760 DHAP D-glyceraldehyde L-arginine DHAP D-erythrose mtgA Nα,Nε-diacetyl- tRNA ligase: tRNA ligase: -tRNA -tRNA -tRNA tRNA ligase: fusion protein: -tRNA tRNA ligase: tRNA ligase: tRNA ligase: -tRNA -tRNA tRNA ligase: ligase: subunit beta: tRNA ligase: ligase: tRNA ligase: ligase: tRNA ligase: dehydrogenase: UDP-N-acetyl-α-D-muramoyl-L-alanyl- lysyl-D-alanine D-ala FSB75_RS01895 FSB75_RS02035 ligase: thrS ligase: metG ligase: metG FSB75_RS04590 FSB75_RS05555 ligase: trpS FSB75_RS11820 FSB75_RS13350 FSB75_RS14165 ligase: lysS ligase: asnS FSB75_RS17000 serS FSB75_RS20035 FSB75_RS18130 alaS FSB75_RS18395 aspS FSB75_RS21190 preA γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine a [bis(guanylyl 2-oxoglutarate 5,6-dihydrothymine a peptidoglycan di-trans,octa-cis ala molybdopterin) an L-methionyl- dehydrogenase dimer (E. faecium -undecaprenyl cofactor an L-arginyl- an L-valyl- an L-threonyl- an L-methionyl- an L-prolyl- an L-glutaminyl- an L-tryptophanyl- an L-histidyl- an L-glutamyl- an L-cysteinyl- an L-lysyl- an L-asparaginyl- an L-leucyl- an L-seryl- an L-phenylalanyl- an L-isoleucyl- an L-alanyl- Gly an L-aspartyl- an L-tyrosyl- dihydropyrimidinase: Arg Val Thr [elongator Met Pro Gln Trp His Glu Cys Lys Asn Leu ser Phe Ile Ala a glycyl-[tRNA ] asp Tyr E1 component: , tetrapeptide) diphosphate chaperone]-S- [tRNA ] [tRNA ] [tRNA ] Met [initiator tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] hydA tRNA ] FSB75_RS07665 xanthosine adenosine inosine guanosine sulfanyl-L-cysteine 3-(carbamoylamino)- 2-methylpropanoate quinoxaline-2- ditrans,octacis- a peptidoglycan 3-benzyl-3,6 - an S-(1-hydroxy- β 34 a nucleoside 34 -ureidopropionase: purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside a 5,10- a uridine aryl-carrier protein leukotriene-D4 2-oxopropyl) phenylacetyl-CoA a cytidine lys Pentose Phosphate Pathways gly carboxyl adenylate undecaprenyldiphospho- dimer (S. aureus) bis(cysteinylglycine) triphosphate RNA ATP Amino Acid Biosynthesis FSB75_RS07485 phosphorylase: phosphorylase: phosphorylase: phosphorylase: methylenetetrahydrofolate in tRNA N-acetyl-(N- - 6-(hydroxymethyl) -[protein]- phenylacetate- biotin in tRNA Ile2 FSB75_RS20255 FSB75_RS20255 FSB75_RS20255 FSB75_RS20255 L-cysteine CoA oxygenase Secondary Metabolite Biosynthesis pentose phosphate (R)-3-amino-2- acetylglucosaminyl) D-alanyl-D-alanine -diketopiperazine muramoyl-L-alanyl-γ-D- membrane DNA-directed subunit L-histidine biosynthesis L-arginine biosynthesis III ammonia L-cysteine biosynthesis I pathway (oxidative branch) I methylpropanoate tRNA uridine-5- acyl carrier protein: carboxypeptidase/ tRNA L-lysine biosynthesis I superpathway of branched chain amino acid biosynthesis L-tryptophan biosynthesis α-D-ribose- isoglutaminyl-L-lysyl- dipeptidase: RNA polymerase PaaJ: paaJ biotin--[acetyl- (via N-acetyl-L-citrulline) assimilation cycle III methylerythritol phosphate pathway II carboxymethylaminomethyl(34) FSB75_RS16685 D-alanyl-D-alanine- membrane DJ-1/PfpI/YhbO lysidine(34) fluoroacetate and D-glucopyranose 1-phosphate (glycyl) -D-alanyl-D-alanine FSB75_RS16560 subunit omega: CoA-carboxylase] synthesis GTPase MnmE: mnmE acyl carrier protein: 5 dipeptidase: family deglycase/ phenylacetate- synthetase PRPP fluorothreonine biosynthesis 6-phosphate endopeptidase: dacB D-glyceraldehyde glucose-6- pyrimidine deoxyribonucleotides membrane FSB75_RS20475 protease: CoA oxygenase/ ligase: TilS: tilS asp pyruvate thr glu gln glu ser superpathway of L- pyruvate tRNA uridine-5- FSB75_RS02750 penicillin- FSB75_RS16560 ATP chorismate ammonium dephosphorylation dipeptidase: reductase: FSB75_RS13040 aspartate kinase: asparagine biosynthesis 3-phosphate fluoride phosphate carboxymethylaminomethyl(34) monofunctional binding membrane [+ 2 isozymes] FSB75_RS17980 phosphoribosyltransferase: biosynthetic-type serine dehydrogenase: nucleoside triphosphate FSB75_RS00320 paaK paaA FSB75_RS01490 threonine pyrophosphohydrolase: D-ribose 5- synthesis enzyme MnmG: mnmG a quinoxaline-2- biosynthetic protein dipeptidase: a lysidine 34 FSB75_RS08600 acetolactate anthranilate synthase: acetyltransferase: 1-deoxy-D-xylulose- FSB75_RS17830 paaB paaC [+ 2 isozymes] ammonia- SAM-dependent 6-phospho phosphate carboxyl-[aryl- peptidoglycan 2: mrdA FSB75_RS00320 2-(1,2-epoxy-1,2- biotinyl-5'- in tRNA Ile2 synthase: ilvN ilvB glutamine FSB75_RS11425 asp mazG AMP RNA a [protein]- lyase: ilvA FSB75_RS21085 5-phosphate chlorinase/ D-glucono- transglycosylase: (R)-lactate adenylate 1-(5-phospho-β-D-ribosyl)-ATP L-aspartyl-4-phosphate synthetase: dCTP dCMP a 5-carboxymethylaminomethyluridine 34 carrier protein] leukotriene-E4 gly L-cysteine dihydrophenyl) (S)-2-acetolactate serine synthase: fluorinase: 1,5-lactone a 7,8-dihydrofolate mtgA N-acetyl-L- FSB75_RS19580 Fatty Acid and in tRNA a peptidoglycan 3-benzyl-3,6 - acetyl-CoA (2Z)-2-aminobut-2-enoate acetyltransferase: FSB75_RS18785 FSB75_RS04490 preQ biosynthesis bifunctional aspartate- glutamate anthranilate PRPP glutamine asparagine asparagine 0 6-phosphogluconolactonase: Lipid Degradation with D,D cross- bis(cysteinyl)- 6- gly ketol-acid FSB75_RS08315 dUTP diphosphatase: dut D-ala phosphoribosyl- semialdehyde synthetase III: synthase synthase 5'-deoxy-5'-fluoroadenosine FSB75_RS00890 nucleoside triphosphate a peptidoglycan di-trans,octa-cis link (S. aureus) (hydroxymethyl) reductoisomerase: acetylglutamate Aromatic Compound Biosynthesis 1-deoxy-D-xylulose β AMP cyclohydrolase/ dehydrogenase: FSB75_RS21410 (glutamine- (glutamine- D-gluconate pyrophosphohydrolase: oleate -oxidation dimer (S. aureus) -undecaprenyl -diketopiperazine ilvC kinase: argB anthranilate O-acetyl-L-serine hydrogen sulfide 5-phosphate GTP phosphoribosyl-ATP FSB75_RS17775 hydrogencarbonate hydrolyzing) hydrolyzing) purine-nucleoside 6-phosphate mazG diphosphate diphosphatase HisIE: (2R)-2,3-dihydroxy- phosphoribosyltransferase: trpD 1-deoxy-D-xylulose- GTP 2-iminobutanoate N-acetylglutamyl- : asnB : asnB chorismate biosynthesis I phosphorylase: dUTP dUMP oleate L-aspartate 4- 3-methylbutanoate dipicolinate biosynthesis 5-phosphate NADP-dependent FSB75_RS06625 glutamine- gln FSB75_RS20255 cyclohydrolase 4 semialdehyde phosphate cysteine [+ 2 isozymes] [+ 2 isozymes] phosphogluconate a [ribosomal a glucosylated an O - 6-O-trans-keto- 6-O-α-mycolyl- queuosine at N-β-aspartyl- hydrolyzing N-(5-phosphoribosyl)-anthranilate D-erythrose reductoisomerase: I FolE: folE UDP-α-D-glucose a [protein]- a [protein]- a DNA methyl an N-modified dihydroxy-acid synthase A: cysK 5-fluoro-5-deoxy-D- oleate--CoA ligase: a sulfurated protein S12] methylthymine H O mycolyl-trehalose trehalose 6- 1-(5-phospho-β-D-ribosyl)-AMP N-acetyl- glutamate FSB75_RS09710 dehydrogenase: gndA glycogenin L-cysteine L-cysteine phosphotriester 2 GTP glu position 34 L-arginine dGDP 4-hydroxy- carbamoyl- 4-phosphate GTP 5-hydroxy-CTP 5-hydroxy-CMP [sulfur carrier] 89 aminoacyl-[tRNA] dehydratase: ilvD gamma-glutamyl- 3-deoxy-7- asp ribose 1-phosphate D-ribulose FSB75_RS17415 L-aspartate in DNA 6-phosphate phosphate of a tRNA Asp tetrahydrodipicolinate phosphate phosphoribosylanthranilate synthase large asn asn cyclohydrolase bifunctional bifunctional vitamin B12- bifunctional phosphate phosphoheptulonate aspartate kinase: MEP 5-phosphate glycogen/starch synthase: 3-methyl-2-oxobutanoate 2-oxobutanoate synthase isomerase: FSB75_RS21105 subunit: gltB cys 7,8- I FolE: folE oleoyl-CoA methylated-DNA-- alpha,alpha- alpha,alpha- isoaspartyl dependent phosphoribosyl- reductase: synthase: FSB75_RS01490 purine deoxyribonucleosides degradation I 30S ribosomal synthase: methylated-DNA-- aminoacyl- trehalose- tRNA glutamyl- FSB75_RS21440 small 1-(2-carboxyphenylamino)-1- dihydroneopterin [protein]-cysteine S- ribosome trehalose- peptidase/L- ribonucleotide AMP cyclohydrolase/ (2S,4S)-4- biosynthetic-type FSB75_RS01385 glu FSB75_RS20745 [+ 2 isozymes] 2-C-methyl-D- protein S12 FSB75_RS03315 [protein]-cysteine S- tRNA phosphate Q synthetase: subunit: carA deoxy-D-ribulose 5-phosphate 3-deoxy- L-aspartyl- 5-fluoro-5-deoxy-D- 3'-triphosphate Macromolecule Modification methyltransferase: small subunit- phosphate asparaginase: reductase: phosphoribosyl-ATP hydroxy-2,3,4,5- 2-isopropylmalate branched-chain acetolactate N-acetyl-L- erythritol 4-phosphate methyltransferase: D-arabino- 4-phosphate ribulose 1-phosphate 6-carboxytetrahydropterin adenosine methylthiotransferase glycogen/starch hydrolase: dependent synthase (UDP- synthase (UDP- FSB75_RS17105 FSB75_RS00470 FSB75_RS09485 diphosphatase HisIE: synthase: glutamate 5- carbamoyl- indole-3-glycerol phosphate cytidylyltransferase: 2'-deoxyinosine 2'-deoxyadenosine 2'-deoxyguanosine FSB75_RS03170 FSB75_RS13715 tetrahydrodipicolinate amino acid synthase: ilvN ilvB heptulosonate synthase QueD: queD tRNA-uridine 2-thiolation nucleotides RimO: rimO synthase: arfB GTPase A: rsgA forming)/trehalose- forming)/trehalose- FSB75_RS06625 4-hydroxy- FSB75_RS08435 transaminase: semialdehyde phosphate synthase TrpC: trpC L-alanine L-glutamate FSB75_RS20635 (2E,9Z)- methylated-DNA-- GDP (S)-2-aceto-2- 7-phosphate aspartate- 6-carboxytetrahydropterin and selenation (bacteria) degradation III FSB75_RS03615 methylated-DNA-- aminoacyl-tRNA [+ 5 isozymes] phosphatase: phosphatase: glutamyl- 1-(5-phospho-β-D-ribosyl)- tetrahydrodipicolinate FSB75_RS08415 N-acetylornithine synthase biosynthesis III biosynthesis III 4-(cytidine 5'- octadecenoyl-CoA [protein]-cysteine S- [protein]-cysteine S- hydroxybutanoate 3-dehydroquinate semialdehyde synthase: FSB75_RS07935 a [ribosomal hydrolase: trehalose-FSB75_RS03915 FSB75_RS03915 queuosine at 5-[(5-phosphoribosylamino) aminotransferase: large diphospho)-2-C- an unsulfurated methyltransferase: α α arg asp reductase: dapB (2S)-2-isopropylmalate [+ 2 isozymes] ketol-acid (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate dehydrogenase: AMP purine-nucleoside purine-nucleoside purine-nucleoside 5'-deoxyadenosine protein S12]-3- methyltransferase: FSB75_RS13450 , '-trehalose position 34 FSB75_RS01395 subunit: carB 2-oxoglutarate synthase: aroB fluoroacetaldehyde 6-carboxy-5,6,7,8- cys met a glucosylated UDP FSB75_RS03170 H + trans-keto- methylideneamino]imidazole- FSB75_RS17775 methyl-D-erythritol [sulfur carrier] FSB75_RS13715 phosphate 6-α-mycolate Asp (S)-2,3,4,5- reductoisomerase: L-tyrosine cys phosphorylase: phosphorylase: phosphorylase: methylsulfanyl- GDP of a tRNA + + 4-carboxamide glutamate 4-(cytidine 5'- tetrahydropterin AMP nucleosidase: glycogenin mono-mycolate H RS11705 H 3-isopropylmalate tryptophan synthase: cysteine FSB75_RS20255 FSB75_RS20255 89 tetrahydrodipicolinate ilvC N-acetyl-L- carbamoyl biosynthesis I synthase large 3-dehydroquinate L-aspartate 4- cysteine FSB75_RS20255 (S)-3-hydroxy-(9Z) L-aspartate 1-(5-phosphoribosyl)-5- dehydratase: val trpB FSB75_RS21125 desulfurase: diphospho)- 7-carboxy-7- FSB75_RS05455 an N-modified an uncharged 2,3,4,5- (R)-2,3-dihydroxy- ornithine phosphate subunit: gltB semialdehyde desulfurase: -octadecenoyl-CoA a [protein]-S- a [protein]-S- [(5- phosphoribosylamino) leuD leuC FSB75_RS19760 type II 3- 2-C-methyl-D- deazaguanine 2-deoxy-α-D- a thymine in DNA [DNA] amino acid tRNA tetrahydropyridine- 3-methylpentanoate ser chorismate FSB75_RS19760 adenine methyl-L-cysteine methyl-L-cysteine methylideneamino]imidazole-4- indole glu dehydroquinate 4-hydroxy- erythritol kinase: synthase: + + 2,6-dicarboxylate N- N-acetylornithine L-isoleucine chorismate mutase: IscS subfamily ribose 1-phosphate H RS00865 H carboxamide isomerase: hisA 2-isopropylmaleate dihydroxy-acid dehydratase: aroQ tetrahydrodipicolinate FSB75_RS10820 fluoroacetate FSB75_RS13530 IscS subfamily succinyltransferase: carbamoyltransferase: biosynthesis IV FSB75_RS20730 cysteine 4-fluorothreonine uracil degradation synthase: 2-phospho-4-(cytidine cysteine 6 phosphoribulosylformimino- dehydratase: ilvD 7-carboxy-7- 3-oxo-(9Z)- a mature peptidoglycan a [DNA]-3'- a 5'-phospho- a [protein]- an O - sn-glycero-3- a 1-acyl-2- 6-O-cis-methoxy- an N-terminal- a peptide with FSB75_RS06225 3-isopropylmalate FSB75_RS01400 tryptophan synthase: chorismate mutase: desulfurase: 3-dehydroshikimate + β I (reductive) FSB75_RS21440 5'-diphospho)-2-C- deazaguanine desulfurase: (meso-diaminopimelate NAD methylguanine phospho-N- arachidonoyl- D-glycero- -D- mycolyl-trehalose L-methionyl-L- a DNA segment an N-terminal AICAR-phosphate dehydratase: (3S)-3-methyl-2- propanoate trpB FSB75_RS21125 FSB75_RS20745 FSB75_RS11880 octadecenoyl-CoA hydroxyl [DNA] L-cysteine ATP dADP + + N-succinyl-2-amino- (2S,4S)-4- methyl-D-erythritol FSB75_RS11880 containing) in DNA manno-heptose 6-phosphate alanyl-[protein] recombinase L-methionine H AtpG H leuD leuC oxopentanoate propanoate:CoA prephenate uracil ala acetyl-CoA C- (arachidonoyl) sn-glycerol bifunctional 6-ketopimelate N-acetyl- hydroxy-2,3,4,5- 2-C-methyl-D- an [L-cysteine 1-phosphate RecA: recA vitamin B12- ligase (AMP- acyltransferase: ethanolamine 3-phosphate CTP alpha,alpha- imidazole glycerol branched-chain L-citrulline tetrahydrodipicolinate erythritol 2,4- desulfurase]-S- ATP-dependent dependent (2R,3S)-3-isopropylmalate forming): acs trp prephenate endolytic methylated-DNA-- type I methionyl DDE-type type I methionyl phosphate amino acid cyclodiphosphate sulfanyl-L-cysteine FSB75_RS04165 DNA ligase: trehalose- ribonucleotide acetylcitrulline propanoyl-CoA dehydrogenase: preQ transglycosylase [protein]-cysteine S- D-glycero-beta-D- aminopeptidase: integrase/ aminopeptidase: F0F1 ATP synthase: hisH hisF 3-isopropylmalate transaminase: 5,6-dihydrouracil shikimate synthase: 0 [+ 2 isozymes] FSB75_RS19855 glycerophosphodiester phosphatidate phosphate reductase: H + H + FSB75_RS20740 arsenate detoxification I (mammalian) Detoxification MltG: mltG methyltransferase: manno-heptose map transposase/ map synthase N-succinyl-L,L-2,6- FSB75_RS08415 deacetylase: FSB75_RS08160 phosphodiesterase: cytidylyltransferase: synthase (UDP- imidazole glycerol dehydrogenase: 2-oxoacid:ferredoxin 3-(4- [+ 2 isozymes] FSB75_RS03170 recombinase: FSB75_RS09485 diaminopimelate FSB75_RS01410 dihydropyrimidinase: dipicolinate (7Z)-hexadecenoyl-CoA FSB75_RS18455 FSB75_RS07920 1-phosphate forming)/trehalose- phosphate leuB [+ 2 isozymes] oxidoreductase hydroxyphenyl) 2-C-methyl-D-erythritol- a [TusA sulfur- FSB75_RS21635 ADP hydA arsenate a mature peptidoglycan a mature peptidoglycan methylated-DNA-- adenylyltransferase: phosphatase: synthase: hisH hisF subunit beta: pyruvate glycerophosphodiester phosphatidate an N-terminal L- a DNA segment (2S)-2-isopropyl- L-citrulline 2,4-cyclodiphosphate carrier protein]-S- [protein]-cysteine S- rfaE2 F0F1 ATP with (L-alanyl-γ-D- strand (non- phosphodiesterase: cytidylyltransferase: FSB75_RS03915 met in reverse met a peptide + + 3-oxosuccinate ile FSB75_RS17890 shikimate 3- sulfanyl-L-cysteine [DNA] NMN trehalose- alanyl-[protein] H H superpathway of L-serine 3-ureidopropanoate (E)-4-hydroxy- glutamyl-meso-2,6- reducing terminus) AMP methyltransferase: FSB75_RS15240 FSB75_RS17265 orientation synthase D-erythro-1-(imidazol-4- argininosuccinate phosphate arsenate purine-nucleoside cis-methoxy- AICAR 2-oxobutanoate and glycine biosynthesis I 3-methylbut- (2E,7Z)- diaminopimeloyl-D- FSB75_RS13715 ADP-D-glycero-β- yl)-glycerol 3-phosphate L,L-diaminopimelate synthase: β 3-phosphoshikimate 1- reductase ArsC: phosphorylase: mono-mycolate -ureidopropionase: 2-enyl- hexadecenoyl-CoA alanine) tetrapeptide D-manno-heptose FSB75_RS01380 3-phospho- carboxyvinyltransferase: FSB75_RS05250 FSB75_RS20255 a CDP-1-acyl- a reduced bifunctional histidinol- biosynthetic-type tyr FSB75_RS07485 diphosphate a [TusD sulfur- a [protein]-S- anandamide sn-glycerol diaminopimelate 4-methyl-2-oxopentanoate D-glycerate aroA a guanine in DNA 2-arachidonoyl- H O c-type phosphatase/ L-arginino- acetolactate phosphoglycerate synthase: ispG carrier protein]-S- arsenate methyl-L-cysteine 3-phosphate 2 epimerase: L-proline 5-enolpyruvoyl- glycerol cytochrome imidazoleglycerol- L-homoserine succinate synthase: ilvN ilvB dehydrogenase: serA β-alanine (E)-4-hydroxy-3- sulfanyl-L-cysteine reductase ArsC: ribose-1-arsenate CcoN an oxidized FSB75_RS03850 branched-chain biosynthesis I shikimate 3- phosphate biosynthesis (S)-2-aceto-2- methylbut-2-en- FSB75_RS14260 (S)-3-hydroxy-(7Z) O c-type amino acid argininosuccinate 3-phosphooxypyruvate phosphate 2 (from L-glutamate) L-threonine -hexadecenoyl-CoA 34 N-acetyl-muramoyl-(L- UDP-N-acetylmuramoyl- a mature DNA with adenine:7,8- 6-O-cis-keto- an N-terminal- a reduced dehydratase meso-diaminopimelate lyase: argH hydroxybutanoate 1-yl diphosphate 4-hydroxy-3- a 5,10- a 2-thiouridine a lipid II a peptidoglycan cytochrome transaminase: chorismate myo-inositol γ γ peptidoglycan dihydro-8- mycolyl-trehalose L-threo-3-phenylserine L-methionyl-L- carbonic acid acetyl-CoA HisB: hisB asp 3-phosphoserine/ biosynthesis arsenate methylenetetrahydrofolate in tRNA alanyl- -D-glutamyl-L- L-alanyl- -D- (n) H O c-type FSB75_RS08415 glu 2-aceto-2-hydroxy- synthase: methylbut-2-enyl biosynthesis a [TusE sulfur arsenite reactive oxygen species degradation oxoguanine mismatch 6-phosphate seryl-[protein] 2 aspartate kinase: phosphohydroxythreonine detoxification lysyl-D-alanyl-D-alanine) glutamyl-meso-2,6- (meso-DAP acetyl-CoA RS01280 cytochrome butanoate FSB75_RS20760 diphosphate 34 carrier protein]-S bifunctional an oxidized 3-(imidazol-4-yl)-2- diaminopimelate [+ 2 isozymes] glutamate 5- arg transaminase: serC D-glucopyranose a uridine in tRNA II (glutaredoxin) diaminopimeloyl- containing) carboxylase FSB75_RS01490 isomeroreductase: L-homoserine reductase: -sulfanylcysteine monofunctional alpha,alpha- carbonic O c-type oxopropyl phosphate decarboxylase: lysA kinase: proB superoxide 3-oxo-(7Z)- tRNA uridine-5- 2 γ [+ 2 isozymes] homoserine chorismate 6-phosphate biosynthetic D-alanyl-D-alanine D-alanine A/G-specific low-specificity type I methionyl biotin carboxyl a reduced -L-glutamyl ilvC O-phospho- 4-hydroxy-3- FSB75_RS10865 inositol-3- arsenate hexadecenoyl-CoA carboxymethylaminomethyl(34) trehalose- anhydrase: cytochrome histidinol-phosphate leu L-aspartyl- kinase: peptidoglycan endolytic adenine L-threonine aminopeptidase: carrier H O c-type 5-phosphate tRNA 2- arsenate superoxide dismutase: carboxypeptidase/ phosphate FSB75_RS13800 2 cbb3-type lys 4-phosphate (R)-2,3-dihydroxy- L-serine methylbut-2-enyl IPP phosphate arsenic acetyl-CoA C- synthesis GTPase MnmE: mnmE protein: accB transaminase: hisC FSB75_RS08380 thiouridine(34) reductase ArsC: transglycosylase: D-alanyl-D-alanine- LD- transglycosylase glycosylase: synthase (UDP- aldolase: ltaE map cytochrome cytochrome glutamate-5- 3-methylpentanoate O-phospho- diphosphate synthase: triglutathione FSB75_RS14555 acyltransferase: tRNA uridine-5- an oxidized synthase FSB75_RS05250 mtgA endopeptidase: dacB carboxypeptidase: MltG: mltG mutY forming)/trehalose- [+ 3 isozymes] c oxidase semialdehyde aspartate- L-homoserine reductase: FSB75_RS05900 superoxide dismutase: FSB75_RS04165 carboxymethylaminomethyl(34) O c-type L-arginine dihydroxy-acid arsenite FSB75_RS04415 malonyl-CoA 2 L-histidinol phosphate semialdehyde isopentenyl- MnmA: mnmA arsenate FSB75_RS02145 penicillin-binding phosphatase: an N-terminal CO H O cytochromea reduced dehydrogenase: degradation I dehydratase: ilvD threonine FSB75_RS10865 Ins(3)P methyltransferase: [+ 2 isozymes] synthesis enzyme MnmG: mnmG benzaldehyde 2 2 dehydrogenase: diphosphate reductase ArsC: di-trans,octa-cis protein 2: mrdA a mature GlcNAc-1,6- an apurinic site FSB75_RS03915 gly met L-seryl-[protein] H O cbb3-type c-type L-methionine biosynthesis III FSB75_RS09875 (arginase pathway) synthase: FSB75_RS15185 a peptidoglycan 2 bifunctional histidinol- FSB75_RS17775 (3S)-3-methyl-2- ser Delta- a 2-thiouridine 34 hydrogen peroxide -undecaprenyl UDP-N-acetyl-α-D- peptidoglycan anhMurNAc- trehalose-cis-keto- cytochrome inositol FSB75_RS14260 (5Z)-tetradecenoyl-CoA (n) adenine within DNA cytochrome FSB75_RS05245 a 5-aminomethyl-2- mono-mycolate an oxidized phosphatase/ L-glutamate-5- arg oxopentanoate isomerase: idi monophosphatase: in tRNA dimethylarsonite arsenite diphosphate N-acetyl-muramoyl-(L- D-ala muramoyl-L-alanyl- (meso-DAP L-Ala-γ-D-Glu- c oxidase L-aspartate 4- glycine biosynthesis II a 7,8-dihydrofolate 34 O c-type imidazoleglycerol- semialdehyde serine threonine thiouridine in tRNA γ 2 L-homoserine branched-chain FSB75_RS15805 tRNA uridine-5- alanyl-γ-D-glutamyl- D-ala -D-glutamyl-meso- containing) DAP-D-Ala cytochromea reduced semialdehyde synthase: thrC catalase: phosphate amino acid hydroxymethyltransferase: a [glycine-cleavage carboxymethylaminomethyl(34) L-lysyl-D-alanine) 2,6-diaminopimelate H O c-type FSB75_RS11565 2 homoserine 6 DMAPP myo-inositol cytochrome dehydratase homoserine O- transaminase: FSB75_RS11035 complex H protein] N - synthesis GTPase MnmE: mnmE cytochrome dehydrogenase: thr (2E,5Z)- c oxidase an oxidized HisB: hisB acetyltransferase: L-ornithine FSB75_RS08415 aminomethyldihydrolipoyl- H O hydroxyl radical gly tRNA uridine-5- 2 tetradecenoyl-CoA UDP-N-acetyl-α-D-muramoyl- α-Kdo-(2->4) an sn-glycero-3- O c-type metX (S)-1-pyrroline- FSB75_RS02305 cacodylate arsenite O L-alanyl-γ-D-glutamyl-L- phosphoenol a [DNA]-3'- a 5'-phospho- 2 [+ 2 isozymes] L-lysine 2 di-trans,octa-cis- sulfite [DNA] a pectin histidinol ornithine- carboxymethylaminomethyl(34) L-alanyl-γ-D-glutamyl-L- -α-Kdo-(2->6) a myristoyl-[acp] phospho-N-(acyl) a RNA-DNA hybrid hydroxyl [DNA] L-allo-threonine a protein sulfite RS02415 sulfitecytochrome 5-carboxylate bifunctional glycine cleavage undecaprenyl phosphate lysyl-D-alanyl-D-alanine pyruvate O-acetyl-L- -oxo-acid glycine cleavage gly synthesis enzyme MnmG: mnmG lysyl-D-alanyl-D-alanine -(lauroyl)-lipid ethanolamine HsdR family type histidinol hydrogen sulfide pyrroline-5- aspartate kinase/ ile system protein ATP-dependent homoserine transaminase: system protein a 5-carboxymethylaminomethyl- IV (E. coli) I site-specific carboxylate homoserine alanine racemization A pectin esterase: Clp protease: dehydrogenase: hisD GcvH: gcvH 34 phosphosulfolactate ribonuclease ATP-dependent rocD GcvH: gcvH 2-thiouridine in tRNA (3E,5Z)-tetradeca- (S)-3-hydroxy-(5Z) phospho-N- D-alanyl-D-alanine deoxyribonuclease: low-specificity histidinol reductase: dehydrogenase [+ 2 isozymes] glycerophosphodiester synthase: HI: rnhA DNA ligase: FSB75_RS00370 FSB75_RS09460 sulfite RS00815 sulfite [+ 2 isozymes] carboxypeptidase/ FSB75_RS05260 L-threonine proC I: thrA L-glutamate-5- glycine a [glycine-cleavage 3,5-dienoyl-CoA -tetradecenoyl-CoA acetylmuramoyl- lipid A biosynthesis phosphodiesterase: [+ 3 isozymes] FSB75_RS09465 dehydrogenase: hisD a [glycine-cleavage ala D-alanyl-D-alanine- FSB75_RS11205 ribonuclease HII: FSB75_RS19855 semialdehyde biosynthesis IV 6 6 acyl-CoA pentapeptide- acyltransferase: FSB75_RS15240 HsdR family type aldolase: ltaE clpX complex H protein] N complex H protein] N endopeptidase: dacB phosphosulfolactate FSB75_RS15540 histidinal pro L-homoserine bifunctional UDP- thioesterase: transferase: FSB75_RS13585 I site-specific L-glutamate -dihydrolipoyl-L-lysine -[(R)-lipoyl]-L-lysine a 5-aminomethyl-2- glycerophosphodiester synthase: a peptide a metal a metal L-homocysteine N-acetylmuramoyl- FSB75_RS09950 FSB75_RS09060 penicillin-binding deoxyribonuclease: a pectate RS02150 thr 34 phosphodiesterase: [DNA] MeOH histidinol gamma- tripeptide:D-alanyl- thiouridine in tRNA Inorganic Nutrient Metabolism 3-oxo-(5Z)- protein 2: mrdA FSB75_RS08920 FSB75_RS19485 acetaldehyde cation cation low-specificity (3E,5Z)- α-D-Kdo-(2->4) FSB75_RS18455 a nucleoside 5'- gly dehydrogenase: hisD semialdehyde D-alanine ligase/ tetradecenoyl-CoA a double stranded DNA methionine methionine L-threonine tetradecadienoate undecaprenyl-diphospho-N- acyl-carrier protein -α-D-Kdo-(2->6) monophosphate dehydrogenase: alanine racemase: acetyl-CoA C- UMP DNA with 5'- histidinol synthase: synthase: aldolase: ltaE selenate reduction acetylmuramoyl-L-alanyl-γ-D- -lipid A (E. coli) L-alanyl-γ-D-glutamyl- (2R)-phospho- pruA an N- terminal phosphate a metal a metal dehydrogenase: hisD metH metH glycine cleavage FSB75_RS11860 assimilatory thiosulfate oxidation III (multienzyme complex) acyltransferase: L-lysyl-D-alanine D-ala sn-glycerol 3-sulfolactate RS07310 gly a 5-methylaminomethyl- glutamyl-L-lysyl- D-alanyl-D-alanine cation cation system protein [+ 2 isozymes] 34 sulfate reduction IV FSB75_RS04165 3-phosphate acylethanolamine glu 2-thiouridine in tRNA selenate his met GcvH: gcvH D-ala a [SoxY protein]-L-cysteine [+ 2 isozymes] tRNA 2- sulfate sulfate [+ 3 isozymes] (3Z)-dodec- selenouridine(34) adenylyltransferase sulfate UDP-N-acetyl-α-D- di-trans,octa-cis cyclic a metal a metal α phosphoenol + (S)-1-pyrroline- RS14430 synthase subunit CysD: cysD adenylyltransferase 3-enoyl-CoA di-trans,octa-cis- UDP- -D-glucose glycerophosphoserine NADPH NAD a uracil in DNA O-phospho- cation cation adenosine 5'- muramoyl-L-alanyl-γ-D- -undecaprenyl pyruvate dehypoxanthine 4-hydroxy-L-threonine cys 5-carboxylate a protein Fatty Acid and Lipid Biosynthesis MnmH: mnmH subunit CysD: cysD undecaprenyl phosphate phosphate dGDP futalosine L-homoserine phosphoselenate glutamyl-L-lysyl-D-alanine L-glutamate ATP- a 5-methylaminomethyl- APS a [SoxY protein]-S- gamma- anteiso-branched-chain 2-(S-geranyl) glycerophosphodiester NAD(P)(+) uracil-DNA dependent zinc a metal a metal Nucleoside and Nucleotide Biosynthesis sulfosulfanyl-L-cysteine (2E)-dodec- low-specificity cystathionine semialdehyde RS01245 palmitate biosynthesis odd iso-branched-chain even iso-branched-chain cis-vaccenate biosynthesis 34 phospho-N- undecaprenyl- 1,4-dihydroxy- glycosylase: metalloprotease fatty acid biosynthesis biotin-carboxyl carrier thiouridine in tRNA phosphodiesterase: transhydrogenase dehydrogenase: cation cation (type II fatty acid synthase) fatty acid biosynthesis fatty acid biosynthesis 2-enoyl-CoA acetylmuramoyl- phosphate glucose phosphoenolpyruvate 6-naphthoate L-threonine ung gamma-synthase: FtsH: protein assembly tRNA 2- cytochrome c: FSB75_RS15240 (Re/Si-specific): pruA superpathway of pyrimidine selenite pentapeptide- phosphotransferase: kinase: FSB75_RS19525 synthase: aldolase: ltaE FSB75_RS16920 FSB75_RS13030 superpathway of superpathway of guanosine superpathway of 5-aminoimidazole inosine-5'-phosphate biosynthesis I superpathway of pyrimidine selenouridine(34) FSB75_RS14690 FSB75_RS09935 ribonucleotides de novo biosynthesis ile a palmitoleoyl-[acp] a [biotin carboxyl- transferase: FSB75_RS15915 pyruvate glycerophosphodiester FSB75_RS07945 adenosine nucleotides nucleotides de novo biosynthesis I ribonucleotide biosynthesis nucleobases salvage an acetoacetyl-[acp] leu val synthase PAPS cytochrome c: FSB75_RS09940 glu a peptide a metal a metal beta-ketoacyl- carrier protein]-L-lysine FSB75_RS09060 kinase: pyk phosphodiesterase: an apyrimidinic uracil RS01810 de novo biosynthesis I MnmH: mnmH FSB75_RS06350 FSB75_RS09945 cation cation AIR branched-chain ACP synthase biotin--[acetyl- phosphoadenylyl- (S)-3- FSB75_RS18455 glycolaldehyde site in DNA gln PRPP uracil 3-oxoacyl- branched-chain a 5-methylaminomethyl- α-D-glucopyranosyl- UMP 1,4-dihydroxy- an unknown gly L-cystathionine hydrogencarbonate IMP 5-(carboxyamino)imidazole amino acid branched-chain II: fabF CoA-carboxylase] a [SoxY protein]-S- a [SoxY protein]-S hydroxydodecanoyl-CoA bifunctional pyr operon [acyl-carrier- an (11Z)-3-oxooctadec- 2-(Se-phospho) sulfate reductase: undecaprenyl-diphospho-N UMP diphosphoundecaprenol IMP asp amidophosphoribosyltransferase: ribonucleotide synthase: amino acid amino acid 6-naphthoate compound transcriptional regulator/uracil transaminase: ligase: 34 selenodiglutathione FSB75_RS08330 disulfanyl-L-cysteine -sulfanyl-L-cysteine γ pyruvate protein] 11-enoyl-[acp] selenouridine in tRNA -acetylmuramoyl-L-alanyl- - sn-glycerol NADH NADP + FSB75_RS17590 FSB75_RS01125 FSB75_RS08415 transaminase: transaminase: FSB75_RS13040 dGTP ser chloride RS19650 chloride glutamine- IMP 5-phospho-β- phosphoribosyltransferase reductase: tRNA 2- D-glutamyl-L-lysyl- D-alanine 3-phosphate N5-CAIR FSB75_RS08415 FSB75_RS08415 3-oxoacyl- a [biotin carboxyl- sulfite hydrolyzing dehydrogenase: D-ribosylamine PyrR: pyrR [+ 2 isozymes] fabG selenouridine(34) adenylosuccinate [+ 2 isozymes] [+ 2 isozymes] [acyl-carrier- carrier protein]-N 3-oxododecanoyl-CoA carbamoyl- guaB uracil (3S)-3-methyl-2- synthase octaheme sulfite synthetase: phosphoribosylamine- 5-(carboxyamino)imidazole a (3R)-3- 4-methyl-2- 3-methyl-2- protein] 6 -biotinyl-L-lysine phosphate oxopentanoate MnmH: mnmH 6 an N-terminal- 2''-O-acetyl- an N-terminal- a protein-L- 5-dehydro- chloride RS12890 chloride FSB75_RS12155 -glycine ligase: purD ribonucleotide mutase: purE phosphoribosyltransferase: upp hydroxybutanoyl-[acp] reductase: glutathioselenol reductase: assimilatory acetyl-CoA C- an N -L- phosphoenol a 2-oxo synthase XMP UMP oxopentanoate oxobutanoate a 5-methylaminomethyl- a sulfurated 37 3-methylbutanoate glycerophosphoglycerol L-methionyl-L- Ala L-methionyl-L- 2-oxoisovalerate FSB75_RS08295 sulfate reduction III acyltransferase: threonylcarbamoyladenine pyruvate carboxylate L-ornithine a glycyl-[tRNA ] ADP-ribose methionine- 4-deoxy-D- adenylosuccinate 2-oxoisovalerate 2-oxoisovalerate fabG 2-selenouridine 34 [sulfur carrier] dADP small dehydrogenase: bifunctional a [SoxY protein]-S-(2- in tRNA cysteinyl-[protein] valyl-[protein] (R)-S-oxide glucuronate5-dehydro- synthase: GAR CAIR UMP kinase: a (3R,11Z)-3- FSB75_RS04165 peptide- subunit: carA glutamine- dehydrogenase: dehydrogenase: a [biotin carboxyl- in tRNA hydrogen sulfide 2+ 2+ FSB75_RS13905 FSB75_RS13020 UDP-3-O-[3- hydroxyoctadec- sulfodisulfanyl)-L-cysteine sulfate [+ 2 isozymes] O-acetyl-ADP- 4-deoxy-D- Co Co FSB75_RS19980 hydrolyzing GMP FSB75_RS13020 FSB75_RS13020 carrier-protein dimer]- acetate- glycerophosphodiester methionine (R)-S- ApaG carbamoyl- phosphoribosylaminoimidazolesuccinocarboxamide guanine and guanosine salvage (2S)-2- hydroxymyristoyl] N- 11-enoyl-[acp] sulfate ornithine- type I methionyl D-tyrosyl-tRNA(Tyr) ribose deacetylase: type I methionyl glucuronate Mg 2+ Mg 2+ UDP 6 urea cycle tRNA (N(6)-L- -CoA phosphodiesterase: oxide reductase: synthase: guaA synthase: FSB75_RS04050 methylbutanoyl- acetylglucosamine 3-methylbutanoyl- N -biotinyl-L-lysine hydrogen selenide adenylyltransferase decanoyl-CoA phosphoenolpyruvate -oxo-acid aminopeptidase: isomerase: phosphate isobutanoyl-CoA bifunctional threonylcarbamoyladenosine(37) ligase: acs FSB75_RS18455 aminopeptidase: deacylase: FSB75_RS13985 FSB75_RS17685 adenylo-succinate GMP synthase: nucleoside-diphosphate CoA deacetylase/3- CoA acetyl-CoA acetyl-CoA subunit CysD: cysD kinase: FSB75_RS19525 transaminase: FSB75_RS13070 map kduI synthase UDP-3-O-[3- queuosine biosynthesis I (de novo) -C(2))- methylthiotransferase map [+ 3 isozymes] 3-deoxy-D- FSB75_RS06615 FGAR SAICAR kinase: FSB75_RS04205 guanosine hydroxyacyl-ACP carboxylase carboxylase arg APS pyruvate glycerophosphodiester rocD Co 2+ Co 2+ large hydroxymyristoyl] N- ammonium MtaB: mtaB a [protein]-L- glycero-2,5- CorA dehydratase: carboxyltransferase biotin 3-methylbutanoyl- phosphodiesterase: ADP-D-ribose 2+ 2+ subunit: carB adenylosuccinate UTP purine-nucleoside acetylglucosamine kinase: pyk acetate methionine hexodiulosonate Mg Mg phosphoribosylformylglycinamidine adenylosuccinate subunit beta: carboxylase phosphoadenylyl- diphosphate FSB75_RS15240 an N-terminal L- an N-terminal lyase: purB GMP phosphorylase: FSB75_RS14845 preQ glutamine- 6 AMP CoA Ala synthase subunit PurQ: purQ a (4S)-4-methyl- deacetylase/3- 0 sulfate reductase: a 2-methylsulfanyl-N -L- a proteinogenic L-glutamate-5- met cysteinyl-[protein] a tRNA gly met L-valyl-[protein] lyase: purB CTP synthase: FSB75_RS20255 a 5-methyl-3- a 4-methyl-3- FSB75_RS03745 subunit: accC sulfur (2E)-dec-2-enoyl-CoA 3-oxohhexanoyl- hydroxyacyl-ACP argininosuccinate hydrolyzing FSB75_RS08330 threonylcarbamoyladenine 37 5'-deoxyadenosine an unsulfurated amino acid semialdehyde carbamoyl asp [+ 2 isozymes] FSB75_RS21390 guanine a (2E)-but-2-enoyl-[acp] oxohexanoyl-[acp] oxopentanoyl-[acp] a [carboxyl-carrier reduction II (via met [acp] dehydratase: lyase: argH carbamoyl- [sulfur carrier] pyruvate Mg 2+ MgtA Mg 2+ phosphate AMP guanylate AICAR 6 polysulfide) in tRNA dATP glycerol sn-glycerol FGAM CTP 3-oxoacyl- protein dimer]-N - preQ phosphate synthase sulfite kinase: gmk 3-oxoacyl- 3-oxoacyl- FSB75_RS14845 1 3-phosphate carboxybiotinyl-L-lysine 0 bifunctional hypoxanthine [acyl-carrier- [acyl-carrier- [acyl-carrier- S small subunit: carA aspartate a (2E,11Z)-octadeca- tRNA assimilatory sulfite (S)-3- adenylate kinase: phosphoribosylformylglycinamidine phosphoribosylaminoimidazolecarboxamide phosphoribosyltransferase: hpt protein] protein] protein] L-arginino-succinate L-ornithine carbamoyl- carbamoyltransferase 2,11-dienoyl-[acp] guanosine(34) reductase (NADPH) Mg 2+ MgtE Mg 2+ FSB75_RS17245 GDP cyclo-ligase: FSB75_RS06730 formyltransferase/IMP cyclohydrolase: purH reductase: reductase: reductase: phosphate synthase hydroxydecanoyl-CoA N 6 -(3-methylbut- a 2,3,4-saturated an N 6 -(1-hydroxy- 3''-O-acetyl- an N-terminal- a (1->4)- catalytic subunit: transglycosylase : FSB75_RS08295 an acyl-[acyl- sn-glycero-3- a D-tyrosyl- a D-aspartyl- fabG a butanoyl-[acp] fabG fabG a polysulfide large subunit: carB 2-en-1-yl)- 1,2-diacyl-sn- 2-oxopropyl)- ADP-ribose L-methionyl- met α-D-glucan FSB75_RS01790 a sulfurated [sulfur carrier] phosphoethanolamine [tRNA Tyr ] [tRNA asp ] AIR FAICAR GMP fatty acid biosynthesis Tgt: tgt 37 carrier protein] CTP 1,4-alpha- a (4S,3R)-3- a (3R)-3-hydroxy- a (3R)-3-hydroxy- hydrogen sulfide adenosine in tRNA glycerol 3-phosphate [protein]-L-lysine glycyl-[protein] ADP initiation (type II) a 7-aminomethyl-7- methionine- nucleoside- vitamin B12- hydroxy-4- beta-ketoacyl- 5-methylhexanoyl- 4-methylpentanoyl- polysulfide ornithine carbamoyl phosphate glucan Cd 2+ CadA Cd 2+ bifunctional deazaguanosine 34 argininosuccinate O-acetyl-ADP- R-sulfoxide N-carbamoyl- diphosphate dependent methylhexanoyl- ACP synthase [acp] [acp] reductase carbamoyltransferase: 3-oxodecanoyl-CoA glycerophosphodiester branching vitamin B12- phosphoribosylaminoimidazolecarboxamide a cis-vaccenoyl-[acp] in tRNA tRNA (N6-isopentenyl phosphate phosphatidate DJ-1/PfpI/YhbO D-tyrosyl-tRNA(Tyr) D-tyrosyl-tRNA(Tyr) ribose deacetylase: type I methionyl reductase: L-aspartate [acp] II: fabF acetyl-CoA NrfD: nrfD synthase: phosphodiesterase: protein kinase: ribonucleotide formyltransferase/IMP cyclohydrolase: purH bifunctional bifunctional FSB75_RS01400 acyltransferase cytidylyltransferase: family deglycase/ deacylase: deacylase: FSB75_RS13985 aminopeptidase: dependent acetyl-CoA S-adenosylmethionine:tRNA FSB75_RS01380 acetyl-CoA C- adenosine(37)-C2)- FSB75_RS15240 FSB75_RS17375 GlgB: glgB FSB75_RS04205 reductase: bifunctional UDP-3-O-[3- UDP-3-O-[3- polysulfide PlsX: plsX FSB75_RS07920 FSB75_RS13070 FSB75_RS13070 map L-methionine- dihydroorotase: ribonucleotide carboxylase ribosyltransferase- L-citrulline acyltransferase: methylthiotransferase protease: a (1,6)-α-D- Cd 2+ CadA Cd 2+ FSB75_RS09485 UDP-3-O-[3- a 3-oxohexanoyl-[acp] hydroxymyristoyl] N- hydroxymyristoyl] N- reductase glycerophosphodiester (R)-S-oxide FSB75_RS02670 reductase: IMP guanine and guanosine salvage II carboxyltransferase isomerase: FSB75_RS09090 FSB75_RS04165 MiaB: miaB phosphatidate FSB75_RS17980 hydroxymyristoyl] N- acetylglucosamine acetylglucosamine NrfD: nrfD polyphosphate metabolism phosphodiesterase: ADP-D-ribose glucosyl-(1,4) dihydroorotase: FSB75_RS09485 3-oxoacyl- subunit beta: cytidylyltransferase: acetate α acetylglucosamine deacetylase/3- deacetylase/3- tRNA preQ1(34) S- [+ 2 isozymes] FSB75_RS18455 an N-terminal - -glucan GTP cis-vaccenate 6 Tyr asp FSB75_RS08110 pyrimidine deoxyribonucleotides de novo biosynthesis I [acyl-carrier- FSB75_RS03745 adenosylmethionine a polysulfide N -(3-methylbut-2-en- acyl-carrier protein an acyl phosphate FSB75_RS17265 D-tyrosine a tRNA tRNA D-aspartate met glycyl-[protein] deacetylase/3- hydroxyacyl-ACP hydroxyacyl-ACP long chain an unsulfurated (R)-lactate a [protein]-L-lysine L-fucose FucP L-fucose dADP dGDP guanosine protein] malonyl-CoA octanoyl-CoA 5'-deoxyadenosine 1-yl)-2-(methylsulfanyl) met (S)-dihydroorotate hydroxyacyl-ACP dehydratase: dehydratase: ribosyltransferase- polyphosphate [sulfur carrier] UDP CTP reductase: isomerase QueA: queA adenosine 37 in tRNA ethanolamine sn-glycerol dehydratase: FSB75_RS14845 FSB75_RS14845 ACP S- a CDP-2,3,4-saturated- nucleoside- nucleoside- vitamin B12-dependent fabG 3-phosphate quinone- superpathway of pyrimidine deoxyribonucleoside salvage FSB75_RS14845 a (2E)-5- a (2E)-4- an epoxyqueuosine 34 diacylglycerol diphosphate diphosphate ribonucleotide reductase: malonyltransferase: L-fucose FucP L-fucose dependent CDP a (2E,4S)-4- a (3R)-3- methylhex- methylpent- CDP-diacylglycerol fabD in tRNA polyphosphate exopolyphosphatase: kinase: kinase: 2'-deoxycytidine FSB75_RS09485 guanine dihydroorotate dUDP methylhex- hydroxyhexanoyl-[acp] 2-enoyl-[acp] 2-enoyl-[acp] biosynthesis I tRNA kinase 1: ppk1 FSB75_RS03285 (2E)-oct-2-enoyl-CoA FSB75_RS04205 FSB75_RS04205 vitamin B12-dependent a [2-oxoglutarate- 34 a thiocarboxylated an N-terminal- a negatively an unstable dehydrogenase: 2-enoyl-[acp] a malonyl-[acp] epoxyqueuosine(34) a sulfurated a uridine menadione NADH H + an alkylated DNA GDP-α-D-mannose ribonucleotide reductase: bifunctional SAM dehydrogenase [SAMP] C- glu a (6S)-5- L-methionyl-L- asp O-ureido-L- supercoiled DNA asn RecA filament- FSB75_RS20115 nucleoside 2'-deoxycytidine nucleoside-diphosphate DHAP in tRNA a sugar RS00405 a sugar dGTP hypoxanthine reductase QueG: queG [sulfur carrier] 6 formyltetrahydrofolate homoserine GDP-mannose DNA gyrase/ dATP deaminase: kinase: kinase: FSB75_RS04205 FSB75_RS09485 UDP-3-O-[3- E2 protein] N - terminal glycine threonyl-[protein] DNA complexDNA PRPP phosphoribosyltransferase: hpt beta-ketoacyl- 34 long chain 4,6-dehydratase: amino acid orotate hydroxymyristoyl] N- a 5- a 5- a queuosine octanoyl-L-lysine topoisomerase repair FSB75_RS14565 FSB75_RS06550 dUTP dCDP ACP synthase 3: polyphosphate NADH-quinone DNA-3- a (4S)-4- acetylglucosamine methylhexanoyl- methylhexanoyl- in tRNA (S)-3- tRNA 2- argininosuccinate FSB75_RS06795 IV subunit A: racemase: [+ 2 isozymes] sn-glycerol FSB75_RS18870 bifunctional methyladenine type I methionyl protein dUTP diphosphatase: dut nucleoside-diphosphate methylhexanoyl- [acp] [acp] hydroxyoctanoyl-CoA lipoyl thiouridine(34) oxidoreductase: GDP-mannose FSB75_RS03755 FSB75_RS10550 a sugar RS10450 a sugar orotate dCMP GMP deacetylase/3- 3-phosphate folylpolyglutamate glycosylase: aminopeptidase: synthase: RecO: kinase: FSB75_RS04205 [acp] beta- beta- synthase: synthase nuoK nuoI phosphoribosyltransferase: nucleoside triphosphate hydroxyacyl-ACP map FSB75_RS01380 4,6-dehydratase: type I DNA D-asparagine recO 2'-deoxyuridine (d)CMP kinase: glycerol-3- an acetoacetyl-[acp] synthase/ nuoH nuoF FSB75_RS19955 a stabilized FSB75_RS01805 pyrophosphohydrolase: dCTP xanthine and beta- dehydratase: ketoacyl- ketoacyl- lipA MnmA: mnmA gmd topoisomerase: FSB75_RS09150 Amino Acid Degradation dihydrofolate FSB75_RS11775 GDP-4-dehydro- RecA filament- purine deoxyribonucleosides salvage mazG xanthosine salvage ketoacyl- FSB75_RS14845 ACP ACP phosphate 1-O- 5-oxo-L-proline metabolism topA thymidine kinase: a [2-oxoglutarate synthase: α DNA complex Zn 2+ RS07295 Zn 2+ ACP synthase synthase acyltransferase phosphatidylserine and 34 FSB75_RS11785 a DNA containing an N-terminal L- -D-rhamnose orotidine 5'- dCDP 3-oxooctanoyl-CoA 5'-deoxyadenosine an unsulfurated a [SAMP] C- a 2-thiouridine an alkylated canavaninosuccinate a relaxed DNA FSB75_RS06820 dUMP PlsY: plsY phosphatidylethanolamine met dehydrogenase FSB75_RS03980 an apurinic/ met threonyl-[protein] synthase a (2E)-hex-2-enoyl-[acp] II: fabF II: fabF a [protein] with L-isoleucine degradation I [sulfur carrier] terminal glycine in tRNA nucleobase phosphate [+ 3 isozymes] L-tryptophan degradation to L-glutamine 6 2'-deoxyguanosine 2'-deoxyadenosine thymidine nucleoside- thymidylate synthase: adenine salvage xanthosine II: fabF a 1-acyl-sn biosynthesis I an N-terminal acetyl-CoA C- E2 protein] N apyrimidinic site diphosphate a 7-methyl-3- a 6-methyl-3- -glycerol 3- 2-amino-3-carboxymuconate degradation II -lipoyl-L-lysine NAD + menadiol orotidine-5'- deoxynucleoside deoxynucleoside FSB75_RS09915 purine-nucleoside a CDP-diacylglycerol L-glutamine acyltransferase: a (6S)-5- Zn 2+ RS00645 Zn 2+ dUMP kinase: a (6S)-6-methyl-3- oxooctanoyl-[acp] oxoheptanoyl-[acp] phosphate ile semialdehyde phosphate kinase: kinase: thymidine kinase: dTMP phosphorylase: FSB75_RS04165 formyltetrahydrofolate FSB75_RS04205 oxooctanoyl-[acp] 1-acyl-sn-glycerol- glutaminyl-peptide decarboxylase: FSB75_RS06550 FSB75_RS06550 FSB75_RS06820 adenine FSB75_RS20255 3-oxoacyl- 3-oxoacyl- gln [+ 2 isozymes] thymidylate xanthine 3-phosphate cyclotransferase: trp glutamate pyrF dCTP 3-oxoacyl- [acyl-carrier- [acyl-carrier- a 3-sn-phosphatidyl- a [protein] with branched-chain [+ 2 isozymes] [+ 2 isozymes] synthase: [+ 3 isozymes] tryptophan 2,3- a 5-methylaminomethyl- an XLLG (1S,2R)-1- a 2'- a [protein] N- a [LuxE]-S- [acyl-carrier- a hexanoyl-[acp] protein] protein] acyltransferase: L-serine FSB75_RS01625 an N-terminal amino acid synthase large hexanoyl-CoA β a D-aminoacyl- a ribonucleoside (3R,5S)-3- dGMP dAMP FSB75_RS09915 geranyl 34 GDP- -L-fucose acetylxylan UMP protein] FSB75_RS09960 dioxygenase: subunit: gltB selenophosphate 2-thiouridine xylogulcan ser C-(indol-3- deoxyribonucleoside [DNA] terminal-formyl- (long-chain fatty gln hydroxy-1- dTDP adenine deaminase: ade reductase: reductase: phosphatidylserine glutaminyl-peptide L-glutamate transaminase: diphosphate [tRNA] diphosphate beta-ketoacyl- FSB75_RS17180 glu in tRNA yl)glycerol 5'-triphosphate L-methionine acyl)-L-cysteine vitamin B12- pyrroline-5- UMP kinase: reductase: fabG fabG [+ 2 isozymes] cyclotransferase: FSB75_RS08415 N-Formyl-L- L-histidine degradation I nucleoside-diphosphate a 1,2-diacyl- decarboxylase 3-phosphate amino acid fabG ACP synthase a (3R)-3-hydroxy- a (3R)-3-hydroxy- FSB75_RS03490 [+ 2 isozymes] kynurenine alpha-1,2- dependent acetylxylan carboxylatepyrroline-5- FSB75_RS13905 kinase: FSB75_RS04205 sn-glycerol family protein: racemase: CMP a (3R,6S)-3- II: fabF 7-methyloctanoyl- 6-methylheptanoyl- tRNA 2- fucosyltransferase: DNA polymerase/ D-tyrosyl-tRNA(Tyr) peptide acyl-CoA ribonucleotide esterase: carboxylate UDP XMP FSB75_RS17750 (3S)-3-methyl-2- tryptophan FSB75_RS10550 phosphorylation dTTP hypoxanthine AMP hydroxy-6- [acp] [acp] 3-phosphate a [protein] with his (2E)-hexenoyl-CoA selenouridine(34) FSB75_RS02195 3'-5' exonuclease deacylase: deformylase: reductase: reductase: reductase: oxopentanoate synthase: trpB FSB75_RS10490 dTMP a 3-oxooctanoyl-[acp] phosphatidate an L-1- γ-L-glutamyl histidine FSB75_RS13070 FSB75_RS20670 FSB75_RS01085 FSB75_RS09485 proC nucleoside- CMP methyloctanoyl- bifunctional bifunctional an N-terminal 5- glutathione synthase PolX: a 2'- [+ 4 isozymes] D-glutamine dGDP dADP phosphatidylethanolamine 5-phosphate 2-oxoisovalerate FSB75_RS21125 Hyp diphosphate [acp] UDP-3-O-[3- UDP-3-O-[3- cytidylyltransferase: oxo-L-proline ammonia- L-asparagine MnmH: mnmH FSB75_RS20995 deoxyribonucleoside (d)CMP kinase: hypoxanthine 3-oxoacyl- dehydrogenase: L-kynurenine an XLFG kinase: FSB75_RS09150 bifunctional hydroxymyristoyl] N- hydroxymyristoyl] N- FSB75_RS17265 lyase: hutH degradation I xylogulcan [+ 7 isozymes] 5'-diphosphate nucleoside- nucleoside- phosphoribosyltransferase: hpt [acyl-carrier- FSB75_RS13020 urocanate GDP D-glyceraldehyde an uncharged an N-terminal L- a [LuxE]- a long-chain FSB75_RS04205 CDP UDP-3-O-[3- acetylglucosamine acetylglucosamine phosphatidate (S)-3- a 5-methylaminomethyl- (2E)-3,7- trp a D-amino acid formate acetate xylan gln diphosphate diphosphate dTDP protein] (2S)-2- 3-phosphate tRNA methionyl-[protein] L-cysteine fatty aldehyde hydroxymyristoyl] N- deacetylase/3- deacetylase/3- cytidylyltransferase: urocanate asn hydroxyhexanoyl-CoA 2-selenouridine 34 dimethylocta- UTP kinase: kinase: nucleoside- reductase: methylbutanoyl-CoA nucleoside- IMP acetylglucosamine hydroxyacyl-ACP hydroxyacyl-ACP FSB75_RS07920 hydratase: in tRNA 2,6-diene-1-thiol [DNA] FSB75_RS04205 FSB75_RS04205 diphosphate fabG palmitoleate 5-oxo-L-proline asparaginase: diphosphate deacetylase/3- dehydratase: dehydratase: a CDP- acyl-CoA hydrolysis hutU CTP synthase: kinase: biosynthesis II 3-hydroxy- FSB75_RS13750 kinase: hydroxyacyl-ACP a (3R)-3- FSB75_RS14845 FSB75_RS14845 diacylglycerol 5-oxoprolinase: FSB75_RS21390 dGTP dATP FSB75_RS04205 (plants and bacteria) L-kynurenine 4-imidazolone- asp FSB75_RS04205 dehydratase: hydroxyoctanoyl-[acp] a (2E)-7- a (2E)-6- a 2,3,4-saturated FSB75_RS14435 3-oxohexanoyl-CoA (S)-methylmalonate- N-acetyl-D-glucosaminyl-N- a 2'- N-acetyl-D- a [protein]-L- a (1->4)- (E)-2- 5-propanoate 2-methylbutanoate futalosine ammonium NAD + H O a dipeptide CTP FSB75_RS14845 methyloct-2- methylhept- fatty acyl CoA kynureninase: acetylmuramoyl-L-alanyl-D-glutamyl- deoxyribonucleoside galactosamine 2 β a protein α-D-glucan CTP dTTP bifunctional a palmitoyl-[acp] acyl-CoA pxpB methylcrotonoyl-CoA semialdehyde [DNA] -isoaspartate a (2E,6S)-6- kynU imidazolonepropionase: acetyl-CoA C- 6-carboxy-L-lysyl-D-alanine 5'-triphosphate 6-phosphate protein-L- membrane 1,4-alpha- enoyl-[acp] 2-enoyl-[acp] acyl-ACP thioesterase: methyloct-2- UDP-3-O-[3- FSB75_RS03910 acyltransferase: dipeptidase: zinc-dependent glucan FSB75_RS09950 glu isoaspartate(D- hydroxymyristoyl] N- desaturase: 3-hydroxyanthranilate FSB75_RS04165 CoA-acylating acetate- futalosine nitrite metalloprotease: branching enoyl-[acp] a 2,3,4-saturated DNA polymerase/ N-acetylglucosamine- aspartate) O- FSB75_RS16560 acetylglucosamine FSB75_RS04845 N-formimino- methylmalonate- LD-carboxypeptidase: -CoA hydrolase: reductase: FSB75_RS05580 fatty acid (2S,3S)-3-hydroxy-2- [+ 2 isozymes] 6-phosphate methyltransferase: membrane protein deacetylase/3- a 7- a 6- a palmitoleoyl-[acp] L-glutamate semialdehyde FSB75_RS04415 ligase: acs 3'-5' exonuclease mqnB nirD nirB FSB75_RS02490 dipeptidase: GlgB: glgB hydroxyacyl-ACP methyloctanoyl- methylheptanoyl- methylbutanoyl-CoA butanoyl-CoA PolX: deacetylase: nagA a protein L-β- a peptide glycine cleavage dehydrogenase: a GlgE-glycogen a (6S)-6- [acp] FSB75_RS20995 isoaspartate FSB75_RS00320 dehydratase: [acp] 2-amino-3- FSB75_RS07520 (2S)-2- methyloctanoyl- beta- beta- lipoprotein posttranslational a [glycine-cleavage N-acetyl-D-glucosaminyl-N- [+ 7 isozymes] dehypoxanthine nitrite α-methyl ester a proteinogenic gluconeogenesis I Carbohydrate Biosynthesis α FSB75_RS14845 carboxymuconate- methylbutanoyl- diphosphate D-galactosamine O-antigen building blocks biosynthesis (E. coli) UDP- -D-glucose modification 6 acetylmuramoyl-L-alanyl-D- D-ala AMP futalosine hypoxanthine acetate [acp] ketoacyl- ketoacyl- complex H protein] N CoA 6-phosphate amino acid biosynthesis 6-semialdehyde glycine glutamyl-6-carboxy-L-lysine beta- ACP ACP palmitoleate 2-methylacetoacetyl-CoA glu -[(R)-lipoyl]-L-lysine + UDP-α-D- α-D- a (2E)-oct-2-enoyl-[acp] a [prolipoprotein]- cleavage hydrogencarbonate NADH propanoyl-CoA H (S)-malate D-glucopyranose D-glucopyranose ketoacyl- synthase synthase crotonyl-CoA [DNA] galactose glucopyranose L-cysteine glycine system 6-phosphate 6-phosphate ACP II: fabF II: fabF UDP- 1-phosphate glucose-6- phospho- prolipoprotein acetyl-CoA C- cleavage protein glucose-1-phosphate synthase galactopyranose phosphate sugar mutase: a 9-methyl-3- an 8-methyl-3- diacylglyceryl acyltransferase: L-methionine degradation system GcvH: gcvH thymidylyltransferase II: fabF all-trans- 38- mutase: glf isomerase: protein methylmalonate α D-firefly a uridine a dipetide with an N- β-D-glucose a glucosylated malate α FSB75_RS02470 oxodecanoyl-[acp] oxononanoyl-[acp] transferase: FSB75_RS04165 I (to L-homocysteine) [+ 2 isozymes] isobutanoate sn-glycerol a D-tryptophanyl- -Kdo H O UDP-Galf RfbA: rfbA -D-glucopyranose an (8S)-8- DL-allothreonine heptaprenyl CTP 2 glycogenin malate dTDP-α-D-glucose pgi FSB75_RS01755 GcvH: gcvH (S)-3- semialdehyde Trp luciferyl-CoA 40 in tRNA terminal L-aspartate 6-phosphate dehydrogenase: methyl-3- an octanoyl-[acp] [+ 2 isozymes] diphosphate 1-phosphate [tRNA ] 1,4-alpha- dehydrogenase: F6P 1-phosphate 3-oxoacyl- 3-oxoacyl- a [prolipoprotein]- [+ 3 isozymes]a [glycine-cleavage a [glycine-cleavage hydroxybutanoyl-CoA RluA family inositol-3- mdh met 6 dTDP- oxodecanoyl-[acp] [acyl-carrier- [acyl-carrier- 6 complex H protein] N - pseudouridine phosphate glucan FSB75_RS02330 UTP--glucose- beta-ketoacyl- S-1,2-diacyl-sn- complex H protein] N CoA-acylating 3-deoxy-manno- acyl-CoA glucose 4,6- glutamine-- 3-oxoacyl- protein] protein] acetyl-CoA propanoyl-CoA methionine aminomethyldihydrolipoyl- acetate--CoA synthase: dipeptidase synthase: branching 1-phosphate ACP synthase glyceryl-L-cysteine -dihydrolipoyl-L-lysine methylmalonate- serine geranylgeranylglyceryl/ D-tyrosyl-tRNA(Tyr) octulosonate thioesterase: dehydratase: fructose-6- [acyl-carrier- reductase: reductase: adenosyltransferase: L-lysine ligase: acs FSB75_RS20675 PepE: pepE FSB75_RS05900 protein pyruvate uridylyltransferase: II: fabF hydroxymethyltransferase: heptaprenylglyceryl deacylase: cytidylyltransferase: rfbB phosphate protein] fabG fabG FSB75_RS03325 semialdehyde FSB75_RS09950 GlgB: glgB FSB75_RS05755 lipoprotein acetoacetyl-CoA FSB75_RS11035 phosphate synthase: FSB75_RS13070 kdsB [+ 2 isozymes] Ins(3)P oxaloacetate transaminase reductase: a (3R)-3- a (3R)-3-hydroxy- SAM dehydrogenase: a pseudouridine 38- dTDP-4-dehydro- a 3-oxodecanoyl-[acp] signal peptidase: FSB75_RS18820 a glycogen phosphoenolpyruvate α (isomerizing) UDP-α-D-glucose fabG hydroxy-9- 8-methylnonanoyl- FSB75_RS07520 40 in tRNA 6-deoxy- -D- FSB75_RS05530 L-tryptophan glycine acetyl-CoA C- isobutanoyl-CoA diphosphate a proteinogenic a (3R,8S)-3- methyldecanoyl- [acp] D-firefly luciferin asp phosphoenolpyruvate synthase: ppsA glucopyranose : glmS acyltransferase: AMP acetaldehyde Trp CMP-Kdo amino acid 3-oxoacyl- [acp] L-serine degradation degradation I cleavage gly 3-heptaprenyl- D-tryptophan a tRNA carboxykinase phosphoenolpyruvate dTDP-4- D-glucosamine hydroxy-8- bifunctional an (S-diacyl- FSB75_RS20110 [acyl-carrier- a lipoprotein (via anthranilate) system + sn-glycero- (ATP): pckA methyldecanoyl- bifunctional UDP-3-O-[3- sn-glyceryl) hydrogencarbonate NADH propanoyl-CoA H synthase: ppsA Calvin-Benson-Bassham cycle dehydrorhamnose 6-phosphate protein] signal peptide protein [+ 2 isozymes] 1-phosphate [acp] UDP-3-O-[3- hydroxymyristoyl] N- -L-cysteinyl- SAH 3,5-epimerase: rfbC phosphoglucosamine reductase: signal ser trp GcvH: gcvH bifunctional hydroxymyristoyl] N- acetylglucosamine [apolipoprotein] L-serine tryptophan 2,3- acetyl-CoA phosphoenolpyruvate CO dTDP-4- mutase: glmM fabG peptide [+ 2 isozymes] 2 UDP-3-O-[3- acetylglucosamine deacetylase/3- D-ribulose-1,5- ammonia-lyase: adenosylhomocysteinase: dioxygenase: lysine within 37 2+ a supercoiled α dehydrorhamnose α peptidase cob(II)alamin O-succinyl-L- an adenosine O-succinyl-L- a tripeptide Mg protoporphyrin IX roseoflavin -amylose -D-glucosamine hydroxymyristoyl] N- a (3R)-3- deacetylase/3- hydroxyacyl-ACP FSB75_RS03825 gcv protein H an octanoyl-[acp] cys DMAPP duplex DNA phosphopyruvate bisphosphateribulose 1,5- 3,5-epimerase: rfbC SppA: sppA FSB75_RS02000 N-Formyl-L-FSB75_RS17180 ATP homoserine in tRNA homoserine GTP 1-phosphate acetylglucosamine hydroxydecanoyl-[acp] hydroxyacyl-ACP dehydratase: 2-aminoprop- UvrD-helicase bifunctional 1,4-alpha- hydratase: eno bisphosphate dTDP-4-dehydro- an N-acyl-(S- kynurenine deacetylase/3- dehydratase: FSB75_RS14845 2-enoate adenylate/guanylate domain-containing riboflavin kinase/ glucan carboxylase: β-L-rhamnose bifunctional diacyl-sn-glyceryl) a peptide L-homocysteine L-threonine magnesium branching UDP-α-D-galactofuranose hydroxyacyl-ACP FSB75_RS14845 a (2E)-8- lipoyl(octanoyl) cystathionine tRNA (adenosine(37)-N6) cystathionine peptidase cyclase domain- protein: FAD synthetase: 2-phospho-D-glycerate FSB75_RS07090 dTDP-4- UDP-3-O-[3- -L-cysteinyl- degradation II cob(I)yrinic acid chelatase: protein 2+ 2+ dehydratase: a (2E)-9- transferase -dimethylallyltransferase T: pepT containing protein: FSB75_RS12935 FSB75_RS06735 Hg RS05180 Hg N-acetyl-α-D- biosynthesis hydroxymyristoyl] N- methylnon- [lipoprotein] a,c-diamide gamma-synthase: gamma-synthase: FSB75_RS04505 dehydrorhamnose FSB75_RS14845 LipB: lipB FSB75_RS06325 roseoflavin GlgB: glgB 2,3-bisphosphoglycerate- ribose-5- glucosamine methyldec- 2-enoyl-[acp] adenosyltransferase: FSB75_RS16920 MiaA: miaA FSB75_RS16920 [+ 2 isozymes] reductase: rfbD UDP-α-D-glucose acetylglucosamine 2-iminopropanoate thr cyclic-GMP a single 5'-phosphate independent phosphate 1-phosphate a (2E,8S)-8- 2-enoyl-[acp] L-kynurenine amylopectin D-ribulose 3-phospho- dTDP-β-L- deacetylase/3- FSB75_RS11060 a [glycine-cleavage stranded DNA UDP-glucose 4- methyldec- 6 a proteinogenic Mg- phosphoglycerate isomerase L-alanine N -(3-methylbut- a dipeptide 5-phosphate D-glycerate rhamnose epimerase GalE: galE hydroxyacyl-ACP acyl-carrier protein complex H protein] alginate RS09515 alginate mutase: RpiA: rpiA 2-enoyl-[acp] succinate 2-en-1-yl)- succinate amino acid protoporphyrin UDP-α-D-galactose dehydratase: an 8- tRNA processing degradation IV kynureninase: adenosylcobalamin N 6 -octanoyl-L-lysine L-cystathionine L-homocysteine FSB75_RS18255 L-2-amino-3- 37 ribose 5- UDP-N-acetyl- FSB75_RS14845 a 9- methylnonanoyl- kynU triphosphate adenosine phosphoglycerate UDP-galactopyranose oxobutanoate phosphate α-D-glucosamine methyldecanoyl- [acyl-carrier protein] pyruvate in tRNA 3-phospho-D-glycerate D-ribose 5- kinase: mutase: glf a polycistronic ala ribulose-phosphate isomerase an (8S)-8- a (2E)-dec-2-enoyl-[acp] [acyl-carrier beta- anthranilate glycine C- phosphate FSB75_RS20505 tRNA precursor alanine B: rpiB UDP-Galf methyldecanoyl- protein] ketoacyl- 2503 5-fluorouridine 5'- phosphoglycerate 3-epimerase: dehydrogenase: acetyltransferase: kbl adenine 3-[(1-carboxyvinyl) an N-formyl-L- N-acetyl-4-O- dihomo γ- a [protein]- a (1->4)- transketolase: [acyl-carrier H O H O an acyl-CoA H O kinase: beta- ACP diphosphate 2 2 2 monophosphate α-D-glucan FSB75_RS07600 FSB75_RS09740 in 23S rRNA oxy]benzoate SAM methionylaminoacyl- acetylneuraminate linolenoyl-CoA ATP L-histidine D-xylulose FSB75_RS09825 protein] ketoacyl- synthase noncanonical 1,4-alpha- FSB75_RS20505 13-DPG gly tRNA histidine kinase: 5-phosphate [+ 2 isozymes] beta- ACP II: fabF alanine pyrimidine glucan PRPP biosynthesis L-glutamine adenylate/guanylate FSB75_RS10310 13-DPG D-sedoheptulose ketoacyl- a decanoyl-[acyl- synthase a 1o-methyl-3- a tRNA precursor a tRNA precursor dehydrogenase: 23S rRNA aminofutalosine sialate O- acyl-CoA acyl-CoA nucleotidase, branching transketolase: glyceraldehyde- degradation I peptide inorganic cyclase domain- [+ 14 isozymes] 7-phosphate ACP carrier protein] II: fabF oxoundecanoyl- with a 5' with a 5' FSB75_RS14330 (adenine(2503)-C(2) synthase acetylesterase: thioesterase: thioesterase: YjjG family: protein D-ribose 5- pyruvate deformylase: diphosphatase: containing protein: a [protein]- FSB75_RS09825 3-phosphate synthase a 11-methyl-3- [acp] extension and extension and a )-methyltransferase FSB75_RS10540 FSB75_RS09950 FSB75_RS09950 FSB75_RS17760 type I sedoheptulose phosphate beta-ketoacyl- MqnE: mqnE FSB75_RS20670 FSB75_RS06900 FSB75_RS06325 N-phospho- GlgB: glgB [+ 2 isozymes] dehydrogenase: phosphoribosylpyrophosphate II: fabF a long 3' trailer short 3' extension gln RlmN: rlmN glyceraldehyde- bisphosphatase: fbp oxododecanoyl- 3-oxoacyl- [+ 5 isozymes] cyclic-AMP L-histidine starch gap a (10S)-10- ACP synthase ribonuclease [+ 2 isozymes] 5-fluorouridine 3-phosphate synthetase: FSB75_RS02020 [acp] [acyl-carrier- Asp-tRNA(Asn) 6-amino-6- di-homo-γ- D-sedoheptulose methyl-3- II: fabF P protein a carboxylate ribose-phosphate 3-oxoacyl- protein] /Glu-tRNA(Gln) 2503 met triose-phosphate dehydrogenase: 1,7-bisphosphate D-glyceraldehyde oxododecanoyl- a 2-methyladenine deoxyfutalosine formate a L-methionylaminoacyl- linolenate F6P class I fructose- diphosphokinase: [acyl-carrier- reductase: component: amidotransferase Alcohol Degradation 5'-deoxyadenosine acetate N-acetylneuraminate isomerase: gap 3-phosphate [acp] a 3-oxododecanoyl-[acp] met tRNA H + bisphosphate a tRNA rnpA in 23S rRNA phosphate FSB75_RS01695 D-glyceraldehyde FSB75_RS13460 3-oxoacyl- protein] fabG subunit GatC: gatC DHAP aldolase: a (3R)-3- precursor with a tRNA precursor 3-phosphate class 1 fructose- PRPP [acyl-carrier- 3-oxoacyl- reductase: [+ 13 isozymes] glycerol and glycerophosphodiester degradation FSB75_RS00915 hydroxy-10- with a short bisphosphatase: fbp triose-phosphate glycogen biosynthesis I (from ADP-D-Glucose) protein] [acyl-carrier- fabG a 5' extension glu class II fructose- isomerase: reductase: a (3R)-3-hydroxy-11- methylundecanoyl- 3' extension a 2-oxo a DNA containing N-acetyl-9-O- a double dCDP protein] glycerol methanethiol O-succinyl-L- acetoacetate succinyl-CoA propanoyl-CoA H O an L-aspartyl- histidinol bisphosphate FSB75_RS01695 methyldodecanoyl- [acp] ribonuclease an apurinic/ 2 leu D-glucopyranose 6-phosphate fabG reductase: carboxylate homoserine acetylneuraminate [tRNA Asn ] stranded DNA vitamin B12- class I fructose- a (3R,10S)-3- P protein apyrimidinic site histidinol DNA gyrase/ aldolase: fbaA fabG [acp] bifunctional a glycerophosphodiester Asp-tRNA(Asn) dependent bisphosphate β-D-fructose 1,6- hydroxy-10- component: dehydrogenase: hisD topoisomerase amino acid DHAP phospho- bifunctional UDP-3-O-[3- acyl-CoA /Glu-tRNA(Gln) ribonucleotide bisphosphate methyldodecanoyl- a (3R)-3- rnpA 2-oxoacid:ferredoxin cystathionine 3-oxoacid CoA- sialate O- racemase: aldolase: sugar mutase: UDP-3-O-[3- hydroxymyristoyl] N- endonuclease amidotransferase histidinol IV subunit A: reductase: glycerol oxidoreductase gamma-synthase: transferase: acetylesterase: thioesterase: FSB75_RS10550 FSB75_RS00915 FSB75_RS02470 [acp] hydroxydodecanoyl-[acp] hydroxymyristoyl] N- acetylglucosamine glycerophosphodiester dehydrogenase: hisD FSB75_RS03755 subunit beta: FSB75_RS07985 III: nth FSB75_RS10540 FSB75_RS09950 subunit GatC: gatC FSB75_RS09485 bifunctional phosphodiesterase: FSB75_RS16920 class II fructose- α-D-glucopyranose bifunctional acetylglucosamine deacetylase/3- an uncharged endonuclease III: [+ 2 isozymes] his [+ 2 isozymes] D-leucine UDP-3-O-[3- FSB75_RS17890 FSB75_RS07990 [+ 5 isozymes] a negatively CDP bisphosphate 1-phosphate UDP-3-O-[3- deacetylase/3- hydroxyacyl-ACP tRNA glycerol kinase FSB75_RS15240 FSB75_RS03125 an L-asparaginyl- class I fructose- hydroxymyristoyl] N- Asn supercoiled DNA aldolase: fbaA hydroxymyristoyl] N- hydroxyacyl-ACP dehydratase: GlpK: glpK glycerophosphodiester succinate propanoate [tRNA ] bisphosphate glucose-1-phosphate acetylglucosamine a reduced met acetylglucosamine dehydratase: FSB75_RS14845 Carbohydrate Degradation glycerol kinase phosphodiesterase: an acyl-CoA CO H + acetoacetyl-CoA succinate N-acetylneuraminate aldolase: adenylyltransferase: 2 ferredoxin [iron- a 3'-terminal a 5'-phospho- acetate deacetylase/3- FSB75_RS14845 a (2E)-10- FSB75_RS18455 FSB75_RS00915 FSB75_RS03610 deacetylase/3- GlpK: glpK sulfur] cluster unsaturated sugar [DNA] hydroxyacyl-ACP a (2E)-11- methylundec- 6 37 β-D-fructose 1,6- hydroxyacyl-ACP N -L-threonylcarbamoyladenosine D-galactose degradation I (Leloir pathway) class II fructose- α glycogen/starch α dehydratase: methyldodec- 2-enoyl-[acp] fucose degradation L-arabinose bisphosphate a (1->4)- -D-glucan ADP- -D-glucose dehydratase: -modified tRNA biosynthesis bisphosphate synthase: FSB75_RS14845 β sn-glycerol 3-phosphate FSB75_RS14845 2-enoyl-[acp] -D- degradation I an N-terminal 3-aci- a [protein]-S- a uridine 34 a [DNA]-3'- (+)-7-epi- a mismatched 3-dehydro- class 1 fructose- aldolase: fbaA FSB75_RS03315 a (2E,10S)-10- an L-phenylalanyl- a ribonucleoside a single H O an L-glutamyl- acetoacetyl-CoA galactopyranose 2 β-L-fucopyranose Phe nitropropanoate sulfanyl-L-cysteine in tRNA jasmonoyl-CoA Gln DNA base pair a protein thr L-arabinopyranose arginyl-[protein] [tRNA ] hydroxyl triphosphate stranded DNA [tRNA ] L-gulonate bisphosphatase: fbp glycogen/starch methyldodec- a (2E)-dodec- galactose-1- 3-hydroxybutyryl- DNA 3-dehydro-L- an 10- threonylcarbamoyl- Asp-tRNA(Asn) synthase: 2-enoyl-[acp] 2-enoyl-[acp] epimerase: arabinose CoA mismatch gulonate 2- F6P an 11- methylundecanoyl- nitronate acyl-CoA /Glu-tRNA(Gln) endopeptidase a (1->4)-α-D-glucanFSB75_RS03615 AMP synthase: isomerase: leucyl/phenylalanyl- tRNA 2- exodeoxyribonuclease DNA dehydrogenase: repair protein dehydrogenase: methyldodecanoyl- [acp] FSB75_RS02570 monooxygenase: thioesterase: amidotransferase La: lon FSB75_RS16285 FSB75_RS06960 DHAP tRNA--protein thiouridine(34) III: xth primase: FSB75_RS20785 MutS: mutS yiaK glucose-6- 1,4-alpha-glucan [acp] beta- [+ 2 isozymes] α FSB75_RS11045 FSB75_RS09950 subunit GatC: gatC (S)-3- threonylcarbamoyl- -L-fucopyranose L-arabinose transferase: synthase exodeoxyribonuclease dnaG 2,3-dioxo- phosphate branching a (10S)-10- beta- ketoacyl- α-D- hydroxybutanoyl- [+ 2 isozymes] a peptide AMP synthase: MnmA: mnmA III: xth [+ 2 isozymes] a properly matched L-gulonate isomerase: pgi methyldodecanoyl- ketoacyl- ACP galactopyranose fucose isomerase: isomerase: FSB75_RS02060 an L-glutaminyl- protein GlgB: glgB a dodecanoyl-[acp] [unspecified CoA (L-threonylcarbamoyl)FSB75_RS06215 araA (+)-7-epi- [tRNA Gln ] DNA base pair D-glucopyranose [acp] ACP synthase FSB75_RS09830 3-oxopropanoate nitrite ssDNA/pppN(pN) galactokinase: L-ribulose degradation 34 a 2'- 6-phosphate a glycogen beta- synthase II: fabF adenylate L-phenylalanyl-L- a [protein]- a 2-thiouridine a [DNA]-3'- hybrid jasmonate ketoacyl- FSB75_RS08010 L-fuculose a tRNA Phe products] L-cysteine in tRNA deoxyribonucleoside n -1 beta-ketoacyl- II: fabF a 12-methyl-3- tRNA (adenosine(37)-N6)- ribulokinase: arginyl-[protein] hydroxyl ACP a 13-methyl-3- oxotridecanoyl- α-D-galactose 5'-monophosphate ACP synthase threonylcarbamoyltransferase UDP-α-D-glucose FSB75_RS02580 synthase oxotetradecanoyl- [acp] complex dimerization 1-phosphate II: fabF L-ribulose 5- II: fabF laurate [acp] 3-oxoacyl- a peptidoglycan a [lipoyl-carrier a [protein]- subunit type 1 TsaB: tsaB an N-terminal an L-phenylalanyl- a [protein]- a (12S)-12-methyl- 3-oxoacyl- [acyl-carrier- L-fuculose phosphate a proteinogenic glutathione a 3-oxoacid succinyl-CoA FAD fumarate [DNA] (S)-5-hydroxyisourate 6 L-tyrosine an unfolded Phe L-threonine dimer (generic) asp protein]-N -[(R) a 3-oxotetradecanoyl- AMP-binding [+ 2 isozymes] L-lysyl-[protein] [tRNA ] amino acid protein 3-oxotetradecanoyl- [acyl-carrier- protein] an N 6 -L- 1-phosphate L-ribulose-5- DNA polymerase -dihydrolipoyl]- phosphate [acp] protein: protein tyrosine [acp] protein] reductase: threonylcarbamoyladenine 37 phosphate 4- III subunit hydroxyisourate L-lysine FSB75_RS17415 UDP- 3-oxoacid CoA- FAD:protein FMN endolytic dihydrolipoyl phosphatase: chaperonin peptidoglycan biosynthesis I (meso-diaminopimelate containing) Cell Structure Biosynthesis 3-oxoacyl- 3-oxoacyl- reductase: fabG in tRNA epimerase AraD: leucyl/phenylalanyl- L-aspartate gamma/tau: hydrolase: uraH lipid IV biosynthesis (E. coli) glucose 4- transferase: transferase: transglycosylase dehydrogenase: GroEL: groL A [acyl-carrier- [acyl-carrier- fabG a (3R)-3- FSB75_RS02575 tRNA--protein gamma- oxidase: FSB75_RS11015 (S)-2-oxo-4- FSB75_RS05120 lauroyl-CoA epimerase FSB75_RS12770 MltG: mltG lpdA UDP-N-acetyl- protein] protein] a (3R)-3-hydroxy-13- hydroxy-12- D-xylulose glutamyltransferase: ggt FSB75_RS07985 nadB hydroxy-4-carboxy- a [lipoyl-carrier a [protein]- a (3R)-3- transferase: [+ 2 isozymes] a protein α-D-glucosamine reductase: methyltridecanoyl- GalE: galE DHAP (S)-lactaldehyde FSB75_RS07990 a 2'- protein]-N 6 -[(R L-tyrosine hydroxytetradecanoyl- UDP-N-acetyl- reductase: methyltetradecanoyl- 5-phosphate FSB75_RS02060 5-ureidoimidazoline UDP-N-acetylglucosamine fabG [acp] GlcNAc-1,6- deoxyribonucleoside )-lipoyl]-L-lysine [acp] α-D-glucosamine fabG [acp] N-end rule pathway I (prokaryotic) a [protein]-FMN- a lipid II a (3R,12S)-3- an α-(γ-L-glutamyl) anhydro-MurNAc- 2-iminosuccinate succinate 5'-monophosphate 1-carboxyvinyltransferase: a (3R)-3- bifunctional bifunctional L-cysteinylglycine AMP L-threonine L-phenylalanyl- -L-amino acid a 2,3,4-saturated succinate pentapeptide murA acyl-ACP--UDP-N- hydroxy-12- hydroxytetradecanoyl- UDP-3-O-[3- UDP-3-O-[3- leucyl/phenylalanyl- a tRNA Phe α-D- L-lysyl-[protein] 3-oxoacyl-CoA UDP-N-acetyl-α- acetylglucosamine O- methyltetradecanoyl- [acp] hydroxymyristoyl] N- hydroxymyristoyl] N- tRNA--protein UDP-α-D- glucopyranose trehalose degradation II (cytosolic) D-glucosamine- acyltransferase: lpxA [acp] bifunctional acetylglucosamine acetylglucosamine transferase: galactose a [protein] 1-phosphate enolpyruvate bifunctional UDP-3-O-[3- deacetylase/3- deacetylase/3- an N-terminal FSB75_RS02060 N-terminal L- α,α-trehalose a nascent peptidoglycan a 2-O-acetylated an (S)-2- a [histone]-N 6 - guanosine 2251 α-L- UDP-3-O-[(3R)-3- UDP-3-O-[3- hydroxymyristoyl] N- hydroxyacyl-ACP hydroxyacyl-ACP arginyl-[protein] glutathione dihydrolipoamide DNA with lesion selenide UDP-N- leucyl-L-arginine phospho- (meso-DAP containing) hypoglycin A rhamnogalacturonan I halocarboxylate acetyl-L-lysine an L-amino acid rhamnopyranose hydroxymyristoyl]-N- hydroxymyristoyl] N- in 23S rRNA acetylmuramate acetylglucosamine dehydratase: dehydratase: sugar mutase: pyruvate 23S rRNA excinuclease L-rhamnose selenide, acetyl-α-D-glucosamine acetylglucosamine alpha,alpha- dehydrogenase: deacetylase/3- FSB75_RS14845 FSB75_RS14845 FSB75_RS02470 trehalose degradation dehydrogenase (guanosine(2251) ABC subunit UvrA: amino acid mutarotase: water glu bifunctional deacetylase/3- leucyl/phenylalanyl- trehalase TreA: treA endolytic rhamnogalacturonan haloacid histone murB hydroxyacyl-ACP a (2E)-13- a (2E)-12- VI (periplasmic) complex -2'-O)- FSB75_RS12815 racemase: rhaM dikinase UDP-3-O-[3- hydroxyacyl-ACP tRNA--protein D-glucopyranose transglycosylase gamma- acetylesterase: dehalogenase deacetylase: ala UDP-N-acetyl- dehydratase: methyltetradec- methyltridec- dihydrolipoamide methyltransferase [+ 4 isozymes] FSB75_RS10550 [+ 2 isozymes] SelD: selD α glutamate hydroxymyristoyl] N- dehydratase: transferase: 6-phosphate α α α β-D-glucopyranose MltG: mltG glutamyltransferase: ggt FSB75_RS19620 type II: FSB75_RS19885 DNA without β-L- -D-muramate FSB75_RS14845 2-enoyl-[acp] 2-enoyl-[acp] a [protein] , -trehalose -D-glucopyranose acetyltransferase: RlmB: rlmB racemase: FSB75_RS14845 FSB75_RS02060 [+ 4 isozymes] 2-O- a D-amino acid rhamnopyranose selenophosphate acetylglucosamine an N-terminal N-terminal L- FSB75_RS09690 lesion murI FSB75_RS08130 2251 UDP-N- deacetylase/3- a (2E,12S)-12- a (2E)-tetradec- L-lysyl-[protein] a mature peptidoglycan a nascent peptidoglycan methylguanosine leucyl-L-lysine alpha,alpha- S-acetyldihydrolipoamide acetylmuramate-- amino acid hydroxyacyl-ACP methyltetradec- 2-enoyl-[acp] with (L-alanyl-γ-D-glutamyl- (meso-DAP containing) a rhamnogalacturonan acetate a [histone]-L-lysine in 23S rRNA a 13- a 12- trehalase TreA: treA hypoglycin B L-cysteinylglycine a (2R)-2- racemase: dehydratase: 2-enoyl-[acp] D-xylose meso-2,6-diaminopimeloyl- with GlcNAc terminus acetate a halide anion L-alanine ligase: methyltetradecanoyl- methyltridecanoyl- type I hydroxy fatty acid FSB75_RS10550 FSB75_RS14845 degradation I D-glucopyranose D-alanine) tetrapeptide FSB75_RS09040 [acp] [acp] UDP-3-O-(3- galactose-1-epimerase: UDP-N-acetyl-α-D- D-glt hydroxymyristoyl) D-xylose FSB75_RS02570 a (12S)-12- a myristoyl-[acp] beta- beta- Glycolysis UDP-N-acetyl- decaprenyl-diphospho-N- a 3-O-acetylated 2-deoxy-D-ribose an [amino-group carrier a [protein]-L- muramoyl-L-alanine α xylose a homogalacturonan + aci-nitroethane pyridoxamine - -D-glucosamine methyltetradecanoyl- [+ 2 isozymes] α-D-glucosamine acetylmuramoyl-pentapeptide rhamnogalacturonan I FMN NAD(P)H H protein]-C-terminal-γ- a stearoyl-[acp] MeOH ketoacyl- ketoacyl- α-D-glucopyranose β-D-glucopyranose 5-phosphate proline (ω = 180) 5'-phosphate UDP-3-O-(3- isomerase: (L-glutamyl)-L-glutamate peptidylprolyl [acp] beta-ketoacyl- ACP ACP glycolysis I (from glucose 6-phosphate) D-glucopyranose 6-phosphate UDP-N- hydroxymyristoyl) 12-methyltridecanoate xylA acyl-ACP catalase: pyridoxamine ACP synthase synthase 13-methyltetradecanoate synthase undecaprenyldiphospho- acetylglutamate isomerase: acetylmuramoyl- glucosamine N- peptidoglycan maturation (meso-diaminopimelate containing) D-xylulose pectate lyase: rhamnogalacturonan deoxyribose- nitronate desaturase: 5'-phosphate beta- II: fabF II: fabF II: fabF D-glucopyranose muramoylpentapeptide beta-N- flavin reductase: FSB75_RS16980 FSB75_RS11565 L-alanine-- FSB75_RS19615 acetylesterase: phosphate monooxygenase: kinase: argB oxidase: pdxH acyltransferase: ketoacyl- acetylglucosaminyltransferase: FSB75_RS16105 [+ 8 isozymes] FSB75_RS04845 D-glutamate lipid II (meso 6-phosphate xylulokinase: [+ 2 isozymes] FSB75_RS19620 FSB75_RS11045 an [amino-group carrier FSB75_RS16550 a 3-oxohexadecanoyl- trehalose degradation aldolase: a [protein]-L- formaldehyde lipid IV biosynthesis (P. putida) diaminopimelate containing) ACP (12S)-12- a 15-methyl-3- a 14-methyl-3- FSB75_RS10680 murG protein]-C-terminal- PLP ligase: murD A [acp] D-mannose [+ 4 isozymes] deoC proline (ω = 0) an oleoyl-[acp] UDP-3-O-(3- synthase oxohexadecanoyl- oxopentadecanoyl- glucose-6- I (low osmolarity) γ monofunctional methyltetradecanoate D-xylulose degradation an unsaturated -(5-phospho-L- phosphate + UDP-N-acetyl- a (3R)-3- hydroxymyristoyl) II: fabF 3-oxoacyl- [acp] [acp] α,α-trehalose a homogalacturonan FMNH NAD(P) glutamyl)-L-glutamate biosynthetic 5-phosphate decaprenyl-pyrophosphoryl- UDP pectate a rhamnogalacturonan 2 acetaldehyde nitrite meso-diaminopimelate α hydroxydecanoyl- UDP-N-acetyl- glucosamine N- [acyl-carrier- 3-oxoacyl- 3-oxoacyl- isomerase: pgi D-mannopyranose D-glyceraldehyde -D-muramoyl-L- peptidoglycan 6-phosphate (N-acetylglucosamine)-N- oligosaccharide acetate type I acetaldehyde [acp] α-D-glucosamine acyltransferase: a (14S)-14-methyl- protein] [acyl-carrier- [acyl-carrier- 6-phosphate 3-phosphate alanyl-D-glutamate transglycosylase: mannose-6- acetylmuramyl-(pentapeptide) 3-oxohexadecanoyl- reductase: protein] protein] lpxD mtgA F6P alpha,alpha- phosphate acyl-ACP--UDP-N- UDP-2-N,3-O-bis[(3R)- [acp] fabG reductase: reductase: UDP-N- a nascent peptidoglycan phosphotrehalase: isomerase, acetylglucosamine O- 3-hydroxytetradecanoyl]- 3-oxoacyl- a (3R)-3- fabG fabG an N 10 - RNase III mRNA an [RNA]-3'- UDP acetylmuramoyl- γ FSB75_RS02085 class I: manA an L-methionyl- H + hydrogencarbonate NADP + FMNH malonyl-CoA H + D-glucopyranose ethanol acyltransferase: lpxA α with (L-alanyl- -D-glutamyl- [acyl-carrier- hydroxyhexadecanoyl- a (3R)-3-hydroxy-15- a (3R)-3-hydroxy-14- class 1 fructose- 6-phosphofructokinase: processing a tRNA precursor 2 ribonucleoside- an acyl phosphate L-alanyl-D- -D-glucosamine fatty acid elongation -- saturated F6P [initiator tRNA Met ] formyltetrahydrofolate vitamin B12- meso-2,6-diaminopimeloyl-D- methylhexadecanoyl- pfkA substrate 2',3'- glucose 1- glutamate--2, 6- protein] [acp] methylpentadecanoyl- bisphosphatase: fbp D-glucopyranose dependent UDP-3-O-[(3R)-3- alanyl-D-alanine) pentapeptide D-glucopyranose cyclophosphate acylphosphatase: dehydrogenase: catalase: reductase: bifunctional [acp] [acp] 6-phosphate diaminopimelate carbonic type III polyketide RNA 2',3'-cyclic FSB75_RS06405 FSB75_RS11565 ribonucleotide D-ala hydroxydecanoyl]- fabG UDP-3-O-[3- bifunctional bifunctional an acetoacetyl-[acp] class I fructose-β-D-fructose 1,6- methionyl-tRNA flavin reductase: FSB75_RS21060 ligase: α anhydrase: ribonuclease ribonuclease Z: synthase: phosphodiesterase: reductase: N-acetyl- -D- lipid X D-alanyl-D-alanine D-alanyl-D-alanine a (3R,14S)-3- hydroxymyristoyl] N- UDP-3-O-[3- UDP-3-O-[3- bisphosphate bisphosphate formyltransferase: FSB75_RS16105 [+ 4 isozymes] FSB75_RS09065 FSB75_RS13800 III: rnc FSB75_RS09175 FSB75_RS11000 an [RNA]-3'-thpR acetaldehyde FSB75_RS09485 D-alanine--D- glucosamine carboxypeptidase/ carboxypeptidase/ hydroxy-14- acetylglucosamine hydroxymyristoyl] N- hydroxymyristoyl] N- aldolase: FSB75_RS08760 a carboxylate D-glucono- lipid-A- a mature peptidoglycan with ribunucleoside- dUDP alanine ligase: α bifunctional D-alanyl-D-alanine- D-alanyl-D-alanine- methylhexadecanoyl- deacetylase/3- acetylglucosamine acetylglucosamine FSB75_RS00915 1,5-lactone UDP-N-acetyl- -D- disaccharide γ FSB75_RS04660 UDP-3-O-[3- endopeptidase: dacB endopeptidase: dacB (L-alanyl- -D-glutamyl-meso- [acp] RNase III + 2'-phosphate muramoyl-L-alanyl- hydroxyacyl-ACP deacetylase/3- deacetylase/3- class II fructose- an N-formyl- CO H O a single-stranded FMN NADPH H octoketide synthase: lpxB 2,6-diaminopimeloyl-D-alanyl- 2 2 γ hydroxymyristoyl] N- penicillin-binding penicillin-binding bifunctional dehydratase: hydroxyacyl-ACP hydroxyacyl-ACP DHAP bisphosphate a tetrahydrofolate an mRNA fragment processing mature tRNA D-alanyl-D-alanine -D-glutamyl-meso- lipid A disaccharide D-alanine) pentapeptide a 3-oxoacyl-[acp] L-methionyl- oligoribonucleotide acetylglucosamine protein 2: mrdA protein 2: mrdA UDP-3-O-[3- FSB75_RS14845 dehydratase: dehydratase: aldolase: fbaA met product mRNA 2,6-diaminopimelate (E. coli) [initiator tRNA ] deacetylase/3- hydroxymyristoyl] N- FSB75_RS14845 FSB75_RS14845 Polymeric Compound Degradation a nascent peptidoglycan a nascent peptidoglycan a (2E)-hexadec- hydroxyacyl-ACP tetraacyldisaccharide acetylglucosamine a (2E)-15- a (2E)-14- triose-phosphate bifunctional UDP- with (L-alanyl-γ-D-glutamyl- with D,D cross-links (meso- 2-enoyl-[acp] 3-oxoacyl- dehydratase: 4'-kinase: lpxK deacetylase/3- isomerase: a generic 7,8-dihydrofolate + + a long-chain a 2'- sn-glycerol N-acetylmuramoyl- methylhexadec- methylpentadec- glycogen degradation II NADPH H hydrogen selenide NADP a reduced FMN NADH H + H O D-glucopyranose an aryl sulfate CAIR meso-2,6-diaminopimeloyl- diaminopimelate containing) [acyl-carrier- pectin degradation II monoglutamate O-acetyl-L-serine 2 deoxyribonucleoside FSB75_RS14845 hydroxyacyl-ACP 2-enoyl-[acp] 2-enoyl-[acp] FSB75_RS01695 chondroitin sulfate degradation I (bacterial) polynucleotide substrate flavodoxin fatty acyl-CoA 3-phosphate tripeptide:D-alanyl- lipid IV (E. coli) D-alanine) tetrapeptide beta- protein] deoxynucleoside glucose 1- 5-(carboxyamino) UDP-3-O-(3- A dehydratase: L-glyceraldehyde D-alanine ligase/ ketoacyl- reductase: a glycogen a methyl-esterified kinase: dehydrogenase: sulfatase: imidazole hydroxydecanoyl) FSB75_RS14845 dihydrofolate acyl-CoA 3-phosphate alanine racemase: LD-carboxypeptidase: ACP fabG D-glyceraldehyde homogalacturonan chondroitin sulfate A S1/P1 Nuclease: cysteine flavodoxin flavin reductase: FSB75_RS18765 FSB75_RS13790 FSB75_RS06270 ribonucleotide -α-D-glucosamine a mature peptidoglycan a (2E,14S)-14- alpha-glucan pectin esterase: reductase: mgrA FSB75_RS11860 a palmitoyl-[acp] a 15- a 14- 3-phosphate FSB75_RS15425 reductase: synthase reductase: thioesterase: [+ 4 isozymes] mutase: purE UDP-3-O-(3- FSB75_RS04415 with D,D cross-links (meso- methylhexadec- synthase a (3R)-3- FSB75_RS00370 FSB75_RS16105 a 2'- [+ 2 isozymes] L-glyceraldehyde methylhexadecanoyl- a 2,3,4-saturated family chondroitin S1/P1 nuclease: FSB75_RS09925 A: cysK FSB75_RS00675 FSB75_RS09950 D-glucono- a phenol UDP-N- hydroxymyristoyl) a nascent peptidoglycan a nascent peptidoglycan a mature peptidoglycan methylpentadecanoyl- II: fabF hydroxyacyl-[acyl- type I [+ 3 isozymes] AIR a nascent peptidoglycan with diaminopimelate containing) 2-enoyl-[acp] bifunctional phosphorylase: AC lyase: deoxyribonucleoside 3-phosphate acetylmuramoyl- with L,D cross links (meso- with (L-alanyl-γ-D-glutamyl- with (L-alanyl-γ-D-glutamyl- [acp] [acp] fatty acyl-[acp] FSB75_RS08220 1,5-lactone glucosamine N- γ carrier protein] glyceraldehyde- glgP a homogalacturonan FSB75_RS10435 5'-monophosphate (L-alanyl- -D-glutamyl-meso- UDP-3-O-[3- + tripeptide--D-alanyl- acyltransferase: diaminopimelate containing) meso-2,6-diaminopimeloyl- meso-2,6-diaminopimeloyl- 5,6,7,8- + + FMNH NAD 3-phosphate NADP acetate NADPH an oxidized H 2 a long-chain fatty acid 2,6-diaminopimelate) tripeptide hydroxymyristoyl] N- α 4-deoxy-β-D-gluc- L-selenocysteine D- alanine ligase: FSB75_RS16550 glycine) tetrapeptide D-alanine) tetrapeptide dehydrogenase: an -limit dextrin chondroitin sulfate C tetrahydrofolate flavodoxin a (14S)-14- acetylglucosamine 4-enuronosyl- a 5'-phosphomononucleotide a 5'-phosphooligonucleotide FSB75_RS18925 palmitate gap UDP-3-O-(3- methylhexadecanoyl- deacetylase/3- 4-alpha- chondroitin (1,3)-N-acetyl-D- a mature peptidoglycan 15-methylhexadecanoate 14-methylpentadecanoate α hydroxymyristoyl) [acp] palmitate- hydroxyacyl-ACP glucanotransferase: D-galactopyranuronate AC lyase: galactosamine 4-sulfate UDP-N-acetyl- -D- with L,D cross-links (meso- a mature peptidoglycan with a mature peptidoglycan glucosamine N- γ CoA ligase: dehydratase: 13-DPG FSB75_RS03035 a [glycine-cleavage a 2'- an α(1,5)- muramoyl-L-alanyl- (L-alanyl- -D-glutamyl-meso- γ FSB75_RS10435 lipid IV (E. coli) CMP-Kdo a diphthine-[translation acyltransferase: diaminopimelate containing) with (L-alanyl- -D-glutamyl- FSB75_RS17415 complex H protein] glycyl-glycine glutathione A canavaninosuccinate methylarsonite 2-chloroacetate propionamide γ-D-glutamyl-meso- 2,6-diaminopimelate) tripeptide FSB75_RS14845 a debranched β a sulfurated [sulfur carrier] SAM deoxyribonucleoside [DNA] L-arabinan L-dopa 4-deoxy- -D-gluc- 6 elongation factor 2] di-trans,octa-cis- lpxD meso-2,6-diaminopimeloyl- a trans-2- α-limit dextrin N -octanoyl-L-lysine 5'-triphosphate haloacid 2,6-diaminopimeloyl- palmitoyl-CoA a 2,3,4-saturated phosphoglycerate 4-enuronosyl- 4-deoxy-β-D-gluc-4- arsenite undecaprenyl phosphate UDP-2-N-[(3R)-3- glycine) tetrapeptide (14S)-14- enoyl-[acyl- aldehydo-D- diphthine-- dehalogenase amidase: 4,5-DOPA D-alanyl-D-alanine fatty acyl-[acp] kinase: (1,3)-N-acetyl--D- enuronosyl-(1,3)-N- 3-deoxy-D-manno- alpha-L- methyltransferase: hydroxydodecanoyl]- methylhexadecanoate carrier protein] glycogen galacturonate gamma- argininosuccinate ammonia ligase: type II: FSB75_RS06605 dioxygenase FSB75_RS20505 galactosamine 6-sulfate acetyl-D-galactosamine octulosonic acid RNA-directed arabinofuranosidase: FSB75_RS15185 3-O-[(3R)-3- phosphorylase: glucuronate lipoyl glutamyltransferase: ggt lyase: argH FSB75_RS11900 extradiol: ygiD phospho-N- transferase: DNA polymerase: FSB75_RS20930 a diphthamide- FSB75_RS09690 hydroxydecanoyl]- glgP isomerase: synthase: lipA dimethylarsonite propanoate acetylmuramoyl- D-glucopyranose FSB75_RS06810 FSB75_RS14725 [translation glycolate 4,5-seco-dopa α-D-glucosamine 3-phospho-D-glycerate uxaC pentapeptide- α-D- γ-L-glutamyl- an α(1,5)- α-L- elongation factor 2] a [glycine-cleavage L-cysteinylglycine L-canavanine fumarate transferase: Cofactor, Carrier, and Vitamin Biosynthesis D-tagaturonate 4-deoxy-L-threo-hex- α-Kdo-(2->6)- L-arabinan arabinofuranose glucopyranose β 5'-deoxyadenosine 6 an unsulfurated glycylglycine CMP 2,3-bisphosphoglycerate- (1,4)- -D-xylan 4-enopyranuronate met complex H protein] N [DNA] FSB75_RS09060 1-phosphate [sulfur carrier] lipid IV (E. coli) independent degradation -[(R)-lipoyl]-L-lysine A lipid X (P. putida) [2Fe-2S] iron-sulfur undecaprenyldiphospho- superpathway of coenzyme A biosynthesis I (bacteria) folate transformations III (E. coli) phosphoglycerate phospho- cluster biosynthesis flavin biosynthesis I (bacteria and plants) adenosylcobalamin 6-hydroxymethyl-dihydropterin a (1->4)-β-D-xylan N-acetylmuramoyl-L- mutase: sugar mutase: lipid-A- salvage from cobalamin diphosphate biosynthesis I D-fructuronate endo-1,4-beta- a [pyruvate dehydrogenase E2 a single- 3,4-dihydroxyphenylacetyl- a [release factor]- a guanine 527 alanyl-γ-D-glutamyl-meso 3-methyl-2- a 5,10- FSB75_RS18255 a sialyloligosaccharide 3'-ketolactose dimethylarsonite a uridine in tRNA (S)-NADPHX disaccharide a tetrahydrofolate FSB75_RS02470 a sulfurated [sulfur carrier] 6 ser L-cysteine desulfurase xylanase: SAM protein] N -octanoyl-L-lysine stranded RNA CoA L-glutamine in 16S rRNA -2,6-diaminopimeloyl- synthase: lpxB oxobutanoate methylenetetrahydrofolate cob(I)alamin peptide chain 16S rRNA tRNA GTP a (1->4)-β-D-xylanFSB75_RS10560 arsenite NAD(P)H-hydrate D-alanyl-D-alanine lipid A GTP 2-phospho-D-glycerate D-glucopyranose release factor (guanine(527)-N(7) dihydrouridine L-serine cysteine 3-methyl-2-oxobutanoate oligosaccharide exo-alpha-sialidase: hydroxyphenylacetyl- methyltransferase: dehydratase: undecaprenyldiphospho- GTP methionine 6-phosphate beta-glucosidase: N(5)-glutamine ammonia-lyase: disaccharide desulfurase: bifunctional polyribonucleotide )-methyltransferase FSB75_RS15185 synthase FSB75_RS03410 muramoylpentapeptide beta-N- hydroxymethyltransferase: synthase: metH FSB75_RS13260 CoA thioesterase FSB75_RS18480 FSB75_RS03825 (P. putida) cyclohydrolase lipoyl synthase: lipA nucleotidyltransferase: pnp methyltransferase: 7 RsmG: rsmG DusB: dusB FSB75_RS19760 3,4-dihydroxy- panB cob(II)alamin phosphopyruvate [+ 8 isozymes] PaaI: paaI an N - acetylglucosaminyltransferase: I FolE: folE prmC trimethylarsine a 5,6-dihydrouridine NADPH tetraacyldisaccharide 2-butanone- dihydrofolate hydratase: eno Amine and Polyamine Degradation methylguanine 527 pyruvate murG IscS subfamily asp cob(I)yrinic acid a [release factor]-N 5 in tRNA lipid II (meso 4'-kinase: lpxK 4-phosphate GTP reductase: β-D-xylopyranose 3-keto-β-D- in 16S rRNA cysteine a,c-diamide glycine cleavage N-acetylneuraminate a nucleoside a single- (3,4- D-glucopyranose -methyl-L-glutamine diaminopimelate lipid IV synthase/GTP 2-dehydropantoate cyclohydrolase FSB75_RS09925serine N-acetylglucosamine a [pyruvate dehydrogenase an oligosaccharide coenzyme A galactose A desulfurase: aspartate 1- adenosyltransferase: 7,8- system protein urea 5'-deoxyadenosine diphosphate stranded RNA dihydroxyphenyl) containing) (P. putida) cyclohydrolase II: I FolE: folE a 7,8-dihydrofolate hydroxymethyltransferase:a 5-methyltetrahydrofolate phosphoenolpyruvate degradation II met E2 protein] N 6 -lipoyl-L-lysine an unsulfurated [sulfur carrier] FSB75_RS11880 decarboxylase: cytidylyl molybdenum dihydroneopterin GcvH: gcvH degradation II acetate FSB75_RS07460 FSB75_RS11060 FSB75_RS11035 FSB75_RS03305 cofactor sulfurylation cob(II)alamin- 3'-triphosphate [+ 2 isozymes] N-acetyl-D- an S-sulfanyl-[L- 2,5-diamino-6- thymidylate bifunctional 5,10- phosphoenolpyruvate glucosamine cysteine desulfurase] (5-phospho-D- cytidylyl molybdenum [corrinoid a (6S)-5-formyltetrahydrofolate phosphoenolpyruvate Carboxylate Degradation N-acetylglucosamine urea β-alanine synthase: α a 3,5,7,9,11,13,15- 46 (R)-pantoate adenosyltranferase] methylenetetrahydrofolate synthase: ppsA kinase: FSB75_RS19525 urease: β RNase R degradation (2E,6E)-farnesyl -D-glucopyranose a guanine Tetrapyrrole Biosynthesis ribosylamino) cofactor (trioxo) FSB75_RS09915 kinase: a 5-L-glutamyl- a -D-galactoside hepta-oxo- a folate Ins(2)P DHAP thr dehydrogenase/5,10-5-formyltetrahydrofolate phosphoenolpyruvate pyruvate ureA an amino acid substrate RNA diphosphate protoheme CTP 1-phosphate in tRNA pyrimidin- 7,8- FSB75_RS01560 [peptide] hexadecanoyl-[PKS-acp] methenyltetrahydrofolatecyclo-ligase: kinase: pyk L-ascorbate 2-oxobutanoate N-acetyl-D- ureB ureC aldo/keto tRNA dihydrofolate methylglyoxal 4(3H)-one pantoate--beta- dihydroneopterin methylenetetrahydrofolate synthase: ppsA acetate inositol threonine tetrapyrrole biosynthesis an [MCD cofactor cyclohydrolase: FSB75_RS05500 degradation II glucosamine ammonium reductase: (guanosine(46)-N7) reductase: synthase: an S-sulfanyl-[cysteine bifunctional 3'-phosphate reductase [NAD(P)H]: metF degradation I conversion beta-glucosidase: glucose-1-phosphate monophosphatase: ammonia- I (from glutamate) alanine ligase: chaperone]-MCD cob(I)alamin- FSB75_RS13525 (bacterial, aerobic) 6-phosphate ribonuclease protoheme IX FSB75_RS10655 -methyltransferase desulfurase]-[disordered- diaminohydroxyphosphoribosylaminopyrimidine to acetyl-CoA cytidylyltransferase: FSB75_RS09925 FSB75_RS15805 FSB75_RS01420 FSB75_RS03310 [corrinoid a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate pyruvate N-acetylglucosamine- gamma- FSB75_RS18480 R: rnr farnesyltransferase: TrmB: trmB lyase: ilvA form scaffold cysteine NAD salvage pathway I (PNC VI cycle) L-ascorbate 2-oxobutanoate [+ 8 isozymes] an N 7 - deaminase/5-amino-6-(5-phosphoribosylamino) adenosyltranferase] acetate 6-phosphate glutamyltransferase: ggt rfbF 9-hydroxy-3,5,7,11,13,15- a 7,8-dihydrofolate methylglyoxal glu desulfurase: 2-oxoisovalerate cyoE 46 myo-inositol 2-oxobutanoate protein] complex uracil reductase RibD: ribD cob(I)yrinic acid bifunctional 5,10- hexaoxohexadecanoyl- methylguanine [cysteine desulfurase]-S- acetate- deacetylase: nagA glutamate-- (R)-pantothenate FSB75_RS19760 D-erythro-7,8- + dehydrogenase: in tRNA 5-amino-6-(5- a,c-diamide NAD methylenetetrahydrofolate -CoA D-galactopyranose a non galactosylated [PKS-acp] tRNA ligase: sulfanylcysteine:[acceptor dihydroneopterin Respiration FSB75_RS13020 D-glucosamine an α-(5-L- a diribonucleotide a nucleoside 5'- CDP-α-D-glucose phospho-D- IscS subfamily adenosyltransferase: dehydrogenase/5,10- dehydroascorbate ligase: acs galactose acceptor protein]-cysteine type III propanoyl-CoA 6-phosphate glutamyl)- a peptide monophosphate ferroheme o FSB75_RS13350 D-ribulose ribosylamino)uracil cysteine dihydroneopterin Glu pantothenate FSB75_RS11060 lipoate biosynthesis methenyltetrahydrofolate acetyl-CoA an L-glutamyl-[tRNA ] sulfurtransferase: 5-phosphate bifunctional desulfurase: 2-oxoglutarate decarboxylation to succinyl-CoA amino acid adenosylcob(III) aldolase: folB cyclohydrolase: acyl-CoA FSB75_RS11880 diaminohydroxyphosphoribosylaminopyrimidine kinase: FSB75_RS11880 NAD+ synthase: and incorporation I a [cysteine desulfurase]- bifunctional alamin-[corrinoid FSB75_RS13525 a [2-oxoglutarate carboxylase glutamyl-tRNA deaminase/5-amino-6-(5-phosphoribosylamino) FSB75_RS15990 6-(hydroxymethyl) allantoin degradation a [cytidylyl molybdenum adenosyltranferase] FSB75_RS16240 α-D-glucosamine α undecaprenyl-diphospho-N 1518 1402 37 S-sulfanyl-[disordered- 3,4-dihydroxy- -7,8-dihydropterin dehydrogenase subunit beta: UDP-N-acetyl- -D-glucosamine a long-chain + adenine / a cytidine a guanine (3Z)-hex- (R)-4'- NAD+ synthase: 10 2,3-dioxo- D-glucopyranose maltopentaose an aryl sulfate a phenol NADPH H reductase: hemA uracil reductase RibD: ribD cofactor chaperone]- an octanoyl-[acp] an N -formyltetrahydrofolate to ureidoglycolate γ 1519 Ins(1)P pyrazinamide NADH form scaffold 2-butanone- cob(I)yrinic acid 6 FSB75_RS07550 6-phosphate -acetylmuramoyl-L-alanyl- - fatty acyl-CoA adenine in 16S rRNA in 16S rRNA in tRNA 3-en-1-ol 5-amino-6-(5- phosphopantothenate 2-amino-4-hydroxy-6- FSB75_RS16240 E2 protein] N L-gulonate I (urea producing) cytidylyl molybdenum a,c-diamide lipoyl(octanoyl) D-glutamyl-L-lysyl- D-alanine ribosomal RNA 16S rRNA tRNA CHAT domain- NAD(+)/ (S)-4-amino-5-oxopentanoate protein] complex 4-phosphate phospho-D- hydroxymethyldihydropteridine -lipoyl-L-lysine 3-dehydro-L- (S)-methylmalonyl- pyruvate decarboxylation to acetyl CoA I glucosamine- inositol cysteine bifunctional cofactor (sulfo-dioxo) adenosyltransferase: transferase 2-oxoglutarate (S)-(+)-allantoin small subunit (cytidine(1402)-2'-O) (guanosine(37)-N1) containing protein: amidase: NADH kinase: synthase/GTP ribitylamino)uracil diphosphokinase: folK gulonate 2- CoA 6-phosphate undecaprenyldiphospho- 4-alpha- aryl-sulfate acyl-CoA monophosphatase: desulfurase: phosphopantothenoylcysteine FSB75_RS11060 LipB: lipB pyruvate methyltransferase -methyltransferase: -methyltransferase FSB75_RS06605 glutamate-1- cyclohydrolase II: (7,8-dihydropterin- nicotinate adenine a [lipoyl-carrier protein] dehydrogenase 2-oxoglutarate deaminase: allantoinase muramoylpentapeptide beta-N- glucanotransferase: sulfotransferase: reductase: FSB75_RS09750 FSB75_RS15805 FSB75_RS15590 FSB75_RS19760 decarboxylase/ NMN 6 dehydrogenase: methylmalonyl- a [pyruvate dehydrogenase dinucleotide N -octanoyl-L-lysine dehydrogenase 6 A: rsmA 1518 rsmI 1 TrmD: trmD semialdehyde 2,1- FSB75_RS07460 6-yl)methyl E1 component: dehydrogenase 6 nagB AllB: allB acetylglucosaminyltransferase: FSB75_RS03035 N -dimethyladenine a 2'-O- an N - (3Z)-hex-3- pyrazine-2- phosphopantothenate-- adenosylcobalamin menaquinol-7 biosynthesis yiaK CoA E2 protein] N -lipoyl-L-lysine FSB75_RS15890 FSB75_RS01085 myo-inositol NADPH aminomutase: hemL IscS subfamily 1-deoxy-L- diphosphate FSB75_RS07665 E1 component: complex E1 murG 6 1519 1402 37 en-1-yl acetate carboxylate nicotinate-nucleotide lipoyl epimerase: mce pyruvate glucosamine- allantoate /N -dimethyladenine methylcytidine methylguanine cysteine glycero-tetrulose cysteine ligase CoaBC: coaBC all-trans- 3-dehydro- component ARP synthase: lipA dihydrolipoyl FSB75_RS07665 6-phosphate in 16S rRNA in 16S rRNA in tRNA 5-aminolevulinate desulfurase: (R)-4'- adenylyltransferase: 1,4-dihydroxy- L-gulonate (R)-methylmalonyl- subunit beta: ditrans,octacis-undecaprenyldiphospho- maltose maltotetraose a long-chain 4-phosphate a [lipoyl-carrier heptaprenyl dehydrogenase: deaminase: allantoicase: UDP an aryl sulfate a phenol FSB75_RS11880 phosphopantothenoyl- pyridoxal 5'-phosphate biosynthesis I FSB75_RS05060 2-naphthoate a [2-oxoglutarate a [2-oxoglutarate CoA FSB75_RS04155 N-acetyl-(N-acetylglucosaminyl)muramoyl- fatty aldehyde protein]-N 6 -[(R)- diphosphate lpdA alc porphobilinogen an S-sulfanyl-[cysteine L-cysteine nicotinate-nucleotide dehydrogenase dehydrogenase nagB γ 6,7-dimethyl-8- methylmalonyl- pyruvate L-alanyl- -D-glutamyl-L-lysyl-D-alanine synthase: hemB desulfurase]-S- D-erythrose dihydrolipoyl]-L-lysine 6 6 ribityllumazine bifunctional adenylyltransferase: E2 protein] N E2 protein] N -S- 3-dehydro- CoA mutase: F6P (S)-ureidoglycolate sulfanyl-[disordered- 4-phosphate bis(guanylyl molybdopterin) dehydrogenase synthase: phosphopantothenoylcysteine FSB75_RS15670 -dihydrolipoyl- succinyldihydrolipoyl- L-gulonate FSB75_RS02630 porphobilinogen form scaffold cofactor sulfurylation (acetyl- UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N-acetylmuramoyl-L- (5Z,8Z,11Z,14Z,17Z) (S)-2-oxo-4- a cytidine 1402 guanine 37 a monocarboxylic FSB75_RS03240 decarboxylase/ L-lysine L-lysine 6-phosphate dihydrolipoyl D-glucopyranose maltohexaose F6P citrate (S)-NADHX 15-cis-phytoene succinyl-CoA transferring) alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine -icosapentaenoyl-CoA hydroxy-4-carboxy- in tRNA Phe acid amide protein] complex phosphopantothenate-- nicotinamide demethylmenaquinol-7 dehydrogenase: in 16S rRNA [cysteine desulfurase]-S- NaMN E1 component 5-ureidoimidazoline 16S rRNA tRNA hydroxymethylbilane cysteine ligase CoaBC: coaBC cys undecaprenyldiphospho- 2-oxo-4-hydroxy- aconitate NAD(P)H-hydrate phytoene sulfanylcysteine:[acceptor 6,7-dimethyl-8-(1- 4-phospho- lpdA subunit (cytosine(1402)-N(4) amidase: synthase: hemC bifunctional a [pyruvate dehydrogenase pyruvate a [pyruvate dehydrogenase muramoylpentapeptide beta-N- 4-alpha- 4-carboxy-5- (guanosine(37)-N1) hydratase: dehydratase: desaturase: protein]-cysteine D-ribityl)lumazine D-erythronate nicotinate fructose-6- acyl-CoA FSB75_RS06605 4'-phosphopantetheine demethylmenaquinone L-xylulose 6 alpha: 6pdhA glucanotransferase: )-methyltransferase -methyltransferase FSB75_RS04100 FSB75_RS03410 crtI cysteine molybdopterin biosynthesis 2-oxoglutarate E2 protein] N - dehydrogenase E2 protein] N -S- acetylglucosaminyltransferase: phosphate thioesterase: ureidoimidazoline preuroporphyrinogen sulfurtransferase: phosphoribosyltransferase: RsmH: rsmH TrmD: trmD riboflavin synthase: desulfurase: methyltransferase/2- dehydrogenase 5-phosphate dihydrolipoyl-L-lysine complex acetyldihydrolipoyl-L-lysine murG FSB75_RS03035 aldolase: fsa FSB75_RS09950 decarboxylase: uraD an N 4 - an N 1 - 9,15,9'-tri-cis FSB75_RS11880 pantetheine- pncB a monocarboxylate D-threo-isocitrate NADH a [cysteine FSB75_RS21215 FSB75_RS19760 methoxy-6-polyprenyl- E1 component: dihydrolipoamide (S)-(+)-allantoin methylcytidine 1402 methylguanine 37 -ζ-carotene uroporphyrinogen- phosphate desulfurase]-(S- (3R)-3-hydroxy-2-oxo- cys 1,4-benzoquinol FSB75_RS07665 acetyltransferase: in 16S rRNA in tRNA Phe III synthase: riboflavin IscS subfamily ditrans,octacis-undecaprenyldiphospho-N- UDP maltose D-glyceraldehyde sulfanyl) -[disordered- adenylyltransferase: 4 phosphooxybutanoate methylase UbiE: ubiE FSB75_RS08130 maltopentaose dihydroxyacetone (5Z,8Z,11Z,14Z,17Z) coenzyme A FSB75_RS18160 2 cysteine 2-oxoglutarate L-ribulose 5- β 3-phosphate form scaffold coaD cysteine acetyl-(N-acetyl- -D-glucosaminyl)muramoyl-L- -icosapentaenoate uroporphyrinogen- bifunctional 3-phosphoserine/ desulfurase: bacillithiol biosynthesis dehydrogenase phosphate D-gluconate γ protein] complex NAD de novo biosynthesis 3'-dephospho- desulfurase: ATP menaquinol-7 alanyl- -D-glutamyl-L-lysyl-D-alanyl-D-alanine III synthase: riboflavin kinase/ phosphohydroxythreonine FSB75_RS11880 complex degradation I (from aspartate) CoA nicotinate FSB75_RS19760 L-ribulose-5- FSB75_RS18205 FAD synthetase: transaminase: serC an [L-cysteine UDP-N-acetyl- dihydrolipoyllysine- dephospho- (S)-malate phosphate 4- a [protein]-α- FSB75_RS06735 4-phosphooxy- desulfurase]-S- α-D-glucosamine IscS subfamily molybdopterin- residue D-gluconate acetyl-CoA dehypoxanthine D-glucopyranose a maltodextrin D-threo-7,8- a [protein] (L-serine/L- a holo [PedD acyl- D-glucopyranose epimerase AraD: SAM HMG-CoA reduced riboflavin a 28S rRNA acrylamide uroporphyrinogen-III a [cysteine desulfurase]- asp CoA kinase: L-threonine sulfanyl-L-cysteine cysteine synthase GTP succinyltransferase: gluconokinase: futalosine dihydroneopterin threonine) phosphate L-glutamate FSB75_RS02575 carrier protein] protein-glutamate O- xylose FMN FSB75_RS04375 cysteine N-acetyl- desulfurase: adenylyltransferase FSB75_RS06075 protein phosphatase RICIN domain- [scaffold protein- L-aspartate 4-hydroxythreonine- odhB ACP S- flavin reductase: amidase: desulfurase: MoeB: moeB D-xylulose D-gluconate 4-alpha- 2C domain- methyltransferase containing protein: isomerase: (2Fe-2S)] complex oxidase: nadB alpha-D- FSB75_RS11880 GTP 3',8- hydroxymethylglutaryl- malonyltransferase: bifunctional coenzyme A 4-phosphate D-glyceraldehyde tetrahydrofolate biosynthesis a carboxy-adenylated 5-phosphate 6-phosphate dehypoxanthine dihydroneopterin CheR: FSB75_RS16105 FSB75_RS06605 xylA 2-iminosuccinate pyruvate FSB75_RS19760 glucosaminyl an [L-cysteine cyclase Secondary Metabolite Degradation glucanotransferase: CoA lyase: containing protein: FSB75_RS09360 riboflavin kinase/ dehydrogenase 3-phosphate bis(guanylyl futalosine aldolase: folB fabD FSB75_RS06970 IscS subfamily L-malate desulfurase]-S- [small subunit of MoaA: moaA FSB75_RS03035 FSB75_RS03345 FSB75_RS08485 a malonyl- a [protein]-L- a 28S rRNA keto-D-fructose FAD synthetase: PdxA: pdxA (7,8-dihydropterin- cyclase: mqnC riboflavin acrylate molybdopterin) sulfanyl-L-cysteine molybdopterin synthase] (8S)-3',8-cyclo-7,8- 5 quinolinate cysteine synthase 6-yl)methyl 2-oxoisovalerate decarboxylation to isobutanoyl-CoA anhydromuropeptides recycling I a [protein] Ser/Thr [PedD acyl- glutamate-O fragments a [co-chaperone]- FSB75_RS06735 synthase 4-hydroxythreonine- 1-deoxy-D-xylulose- cofactor 4-aminobenzoate dihydroguanosine superpathway of β-D- desulfurase: BshA: bshA diphosphate D-galacturonate degradation I cyclic 6-(hydroxymethyl) carrier protein] -methyl-ester [scaffold protein- NadA: nadA 4-phosphate 5-phosphate molybdopterin 5'-triphosphate an [apo BCAA glucuronosides degradation a maltodextrin maltose glycolaldehyde FAD FSB75_RS11880 GlcNAc-1,6- 5'-deoxyadenosine dehypoxanthine -7,8-dihydropterin acetoacetate acetyl-CoA (2Fe-2S)] complex heme b biosynthesis dehydrogenase synthase: synthase aldehydo-D- met a [bis(guanylyl (S)-malyl N- dihydropteroate cyclic pyranopterin dehydrogenase anhMurNAc- futalosine SSQ1 quinolinate I (aerobic) FSB75_RS18785 6 a β-D-glucuronoside PdxA: pdxA molybdopterin) acetyl-α-D- sulfurtransferase: monophosphate E2 protein] N γ galacturonate chaperone: [bis-MGD synthase: folP 2-oxoisovalerate L-Ala- -D-Glu- 3-amino-1- glucosaminide moeB synthase: -lipoyl-L-lysine glucuronate carboxylating cofactor cofactor dehydrogenase: DAP-D-Ala dnaK uroporphyrinogen-III hydroxyacetone 1-deoxy-D-xylulose FSB75_RS20135 2-oxoisovalerate isomerase: a plant soluble DNA combined with p-nitrophenyl- a [chaperone-ATP]- nicotinate- chaperone]-S- chaperone]- bacillithiol 7,8- FSB75_RS13020 D-glucopyranose an insertion sequence (S)-4- uroporphyrinogen 1-phosphate 5-phosphate a thiocarboxylated dehydrogenase: uxaC a proteinogenic leukotriene-C4 heteroglycan exogenous DNA to form β-D-galactoside hydantoin a holo [PedN acyl- homogentisate acetamide [co-chaperone]- dipyrromethane nucleotide sulfanyl-L-cysteine bis-MGD biosynthesis dihydropteroate cyclic pyranopterin element IS30 hydroxymandelate decarboxylase: hemE [small subunit of FSB75_RS13020 amino acid carrier protein] cofactor biosynthesis deacetylase phosphate D-glucopyranuronate a recombinational junctionHolliday junction transposase: mandelate homogentisate [scaffold protein- diphosphorylase: coproporphyrinogen III pyridoxine 5'- bifunctional molybdopterin synthase] D-tagaturonate dihydropyrimidinase: ACP S- amidase: BshB1: bshB1 dihydrolipoyl N-acetyl-β-D- L-alanyl-γ-D- 4-alpha- resolvase RuvX: ruvX FSB75_RS13305 racemase: 1,2-dioxygenase: (2Fe-2S)] complex an apo-[hydroxymethylbilane nadC phosphate folylpolyglutamate beta-glucosidase: hydA malonyltransferase: FSB75_RS06605 (S)-malyl α-D- dehydrogenase: glucosamine-1,6- glutamyl-meso-2,6- tagaturonate glucanotransferase: [+ 5 isozymes] FSB75_RS00625 FSB75_RS08675 synthase]-L-cysteine oxygen-dependent synthase: synthase/ gamma- crossover junction FSB75_RS18480 fabD NaMN sulfo-bis(guanylyl lpdA an [apo BCAA anhydro-N-acetyl- diaminopimeloyl- FSB75_RS03035 an insertion SSQ1 coproporphyrinogen glucosaminide dihydrofolate an [apo BCAA dehydrogenase reductase: glutamyltransferase: ggt endodeoxyribonuclease a malonyl[PedN (R)-4- 4-maleyl- FSB75_RS20315 molybdopterin) dehydrogenase β N-carbamoylglycine sequence IS30 with acetate chaperone E2 protein] N 6 -S-[2- -D-muramate D-alanine FSB75_RS19685 RuvC: ruvC acyl-carrier hydroxymandelate acetoacetate nicotinate-nucleotide oxidase: hemF bacillithiol synthase: 6 aldehydo-D-glucuronate resolution of recombinational ATPase: dnaK a [hydroxymethylbilane cofactor molybdopterin menaquinol-10 biosynthesis E2 protein] N LD- integrated transposon biosynthesis FSB75_RS03980 methylpropanoyl]dihydrolipoyl- a plant soluble junction formation D-galactopyranose protein] synthase] ES intermediate adenylyltransferase: -dihydrolipoyl- carboxypeptidase: glucuronate D-altronate maltose 4-nitrophenol 2 protoporphyrinogen IX pyridoxine 5'-phosphate L-lysine an α-(γ-L-glutamyl) heteroglycan FSB75_RS05060 cysteine- 7,8-dihydrofolate all-trans- L-lysine leukotriene-D4 of two intact strands a [chaperone- FSB75_RS04415 isomerase: D-altronate -L-amino acid an [2Fe-2S] hydroxymethylbilane protoporphyrinogen adding monoglutamate decaprenyl 1,4-dihydroxy- 1,6-anhydro-N- L-alanyl-γ-D- ADP]-[disordered- nicotinate-nucleotide pyridoxamine uxaC cluster protein synthase: hemC enzyme diphosphate 2-naphthoate β dehydratase: form scaffold adenylyltransferase: oxidase: superpathway of heme b biosynthesis from uroporphyrinogen-III acetyl- -muramate glutamyl-meso- 5'-phosphate BshC: bshC FSB75_RS19690 protein] complex a [hydroxymethylbilane FSB75_RS15670 FSB75_RS18140 menaquinol-11 biosynthesis anhydro-N- diaminopimelate D-fructuronate a [histone]-N 6 - a β-D-glucosyl-N phosphoenol oxidase: pdxH + maltotetraose (indol-3-yl) (2S)- synthase] ES intermediate 2-oxoisovalerate 2-dehydro-3- NAD D-glucopyranose maltotriose a glucan a holo [BryP acyl- an adenine in DNA (R)-lactate non- 3 acetylmuramic acetyl-L-lysine -acylsphingosine pyruvate acetamide ethylmalonyl-CoA nicotinate adenine protoporphyrin IX uroporphyrinogen-III bacillithiol all-trans- dehydrogenase: carrier protein] chaperonin hydroxymethylbilane PLP a 7,8-dihydrofolate acid kinase: deoxy-D-gluconate phosphoenolpyruvate DNA adenine methylmalonyl- D-2-hydroxyacid dinucleotide undecaprenyl 1,4-dihydroxy- FSB75_RS13020 ACP S- amidase: molecular FSB75_RS19920 2-dehydro-3- 4-alpha- kinase: FSB75_RS19525 methylase: synthase: hemC ferrochelatase: uroporphyrinogen DMKH2-10 NAD-dependent 4-alpha- glucosylceramidase: CoA dehydrogenase: NAD+ synthase: NAD+ synthase: di-trans,poly-cis dihydrofolate S-adenosyl-L- diphosphate 2-naphthoate 2-oxo acid N-acetyl-D- deoxygluconokinase: pyruvate malonyltransferase: FSB75_RS14240 FSB75_RS06605 chaperone a [hydroxymethylbilane D-mannonate deacylase: glucanotransferase: glucanotransferase: epimerase: mce FSB75_RS00220 FSB75_RS16240 FSB75_RS16240 hemH decarboxylase: hemE reductase: dehydrogenase muramate 6- FSB75_RS20215 fabD ATPase: dnaK -undecaprenyl methionine salvage II bifunctional FSB75_RS19700 FSB75_RS03035 FSB75_RS03035 kinase: pyk a malonyl- [+ 3 isozymes] (2R)- synthase] ES intermediate FSB75_RS09925 FSB75_RS04010 an N 6 -methyladenine (indol-3-yl)acetate pyruvate an [Fe-S cluster 4 phosphate biosynthesis subunit E2: phosphate mannonate pyruvate NAD + protoheme coproporphyrinogen III demethylmenaquinone [BryP acyl- ethylmalonyl-CoA hydroxymethylbilane molybdenum cofactor biosynthesis FSB75_RS01665 N-acetylmuramic dehydratase: KDGP in DNA biosynthesis (2E,6E)-farnesyl thiamine diphosphate SAH methyltransferase/2- carrier protein] IPP a tetrahydrofolate uxuA 2''-O-acetyl- D-glucopyranose a sphingosine chaperone]-ATP synthase: hemC diphosphate methoxy-6-polyprenyl- acid 6- maltose maltotriose a glucan D-glucopyranose biosynthesis I (E. coli) adenosylhomocysteinase: DMKH2-11 ADP-ribose a [histone]-L-lysine nicotinamide ceramide oxygen-dependent oxygen-independent molybdopterin 1,4-benzoquinol phosphate 2-dehydro-3- a holo-[hydroxymethylbilane 2-[(2R,5Z)- FSB75_RS02000 bifunctional isoprenyl coproporphyrinogen coproporphyrinogen molybdate bifunctional methylase UbiE: ubiE etherase: murQ deoxy-D-gluconate synthase] 2-carboxy-4- molybdopterin L-homocysteine N-acetyl-D- 4-hydroxy-2- folate polyglutamylation transferase: oxidase: hemF III oxidase: hemN demethylmenaquinone 2-dehydro-3- methylthiazol-5(2H adenylyltransferase: glucosamine oxoglutarate a [protein]-N 6 - a long-linear an [amino-group carrier protein]- a uracil 1939 (2R,3S)-3- CDP-α-D-glucose thioredoxin methyltransferase/2- menaquinol-10 NAD + a homogalacturonan α-D-glucopyranose a holo [BryU acyl- NAD FSB75_RS14090 )-ylidene]ethyl deoxygluconokinase: α-D-glucan C-terminal-γ-(L-glutamate 5- uroporphyrinogen-I (S)-mandelate HMP-PP FSB75_RS20160 methionine 6-phosphate aldolase/2- acetyl-L-lysine in 23S rRNA isopropylmalate CDP- protoporphyrinogen IX protoporphyrinogen IX pathway methoxy-6-polyprenyl- FSB75_RS19700 semialdehyde-2-yl)-L-glutamate carrier protein] phosphorylation and a tetrahydrofolate phosphate molybdopterin N-acetylglucosamine- dehydro-3-deoxy- N-acetyl-gamma- 23S rRNA 3-isopropylmalate mandelate glucose 4,6- di-trans,octa-cis synthase: metH 1,4-benzoquinol uroporphyrinogen ACP S- transhydrogenation adenine 6-phosphate phosphogluconate 4-alpha- glutamyl-phosphate (uracil(1939)-C(5)) dehydrogenase: racemase: dehydratase: -undecaprenyl molybdate an oxidized methylase UbiE: ubiE KDGP NAD-dependent polygalacturonase: decarboxylase: hemE malonyltransferase: + dinucleotide deacetylase: nagA aldolase: glucanotransferase: reductase: -methyltransferase leuB FSB75_RS00625 NAD bifunctional serine diphosphate protoporphyrinogen thioredoxin met deacylase: FSB75_RS10575 fabD rfbG thiamine diphosphate FSB75_RS19710 FSB75_RS03035 FSB75_RS01385 RlmD: rlmD NAD(+)/ undecaprenyl- oxidase: FSB75_RS18140 menaquinol-11 D-glucosamine FSB75_RS04010 an [amino-group carrier protein]- a malonyl- 1939 4-methyl-2- CDP-4-dehydro-6- folylpolyglutamate hydroxymethyltransferase: molybdopterin coproporphyrinogen I a 5-methyluracil (R)-mandelate NADH kinase: diphosphate thiamine methionine biosynthesis II (Bacillus) 6-phosphate bifunctional C-terminal-γ-(5-phospho- [BryU acyl- oxopentanoate deoxy-α-D-glucose synthase/ FSB75_RS11035 an N 10 - molybdotransferase bifunctional in 23S rRNA FSB75_RS15590 phosphatase: phosphate thioredoxin- adenosyltransferase: 2-(2-carboxy-4- 4-hydroxy-2- a short 1,4- L-glutamyl)-L-glutamate carrier protein] dihydrofolate formyltetrahydrofolate protoporphyrin IX MoeA: phosphoglucosamine 4-hydroxy-2- 2''-O-acetyl- a homogalacturonan a homogalacturonan FSB75_RS17015 disulfide FSB75_RS03325 methylthiazol-5- oxoglutarate nicotinamide a [protein]-L-lysine α-D-glucan NAD kinase: synthase: a 5,10- thiamine- FSB75_RS20160 HMP-PP mutase: glmM oxoglutarate ADP-ribose bifunctional di-trans,octa-cis demethylmenaquinol- reductase: yl)ethyl phosphate aldolase/2- FSB75_RS14100 FSB75_RS03980 methylenetetrahydrofolate phosphate α-D-glucosamine aldolase/2- + folylpolyglutamate -undecaprenyl 8 biosynthesis II ferrochelatase: hemH trxB SAM NADP bifunctional kinase: thiL MoO - dehydro-3-deoxy- dehydro-3-deoxy- synthase/ phosphate 2 1-phosphate all-trans- phosphogluconate XLXG xyloglucan 1915 D-arabinofuranose folylpolyglutamate thiamine molybdopterin phosphogluconate 3-methyl-2- 5,10-methylene- 2-amino-6-[1-hydroxyethyl]- a pseudouridine (2R)-phospho- (2R,3S)-3- ribulose cytidine NAD(P) a tetrahydrofolate dihydrofolate 1,4-dihydroxy- octaprenyl protoheme aldolase: oligosaccharide 5-phosphate 4-guanidinobutyramide synthase/ diphosphate cofactor menaquinol-6 biosynthesis aldolase: oxobutanoate tetrahydromethanopterin 7-methyl-7,8-dihydropterin in 23S rRNA 3-sulfolactate isopropylmalate nucleoside transhydrogenase synthase: 6-naphthoate diphosphate a reduced FSB75_RS19710 23S rRNA dihydrofolate menaquinol-9 biosynthesis thiamine FSB75_RS00210 2-amino-4-hydroxy-6- 2-phosphosulfolactate 3-deoxy-8- 3-isopropylmalate subunit alpha: FSB75_RS03980 thioredoxin amidase: ribulokinase: deaminase: phosphate N-acetyl-α-D- 3-methyl-2-oxobutanoate hydroxymethyldihydropteridine (pseudouridine(1915)- phosphatase: phosphooctulonate dehydratase: synthase: 10 bifunctional FSB75_RS02580 FSB75_RS14565 FSB75_RS09940 an N - NADP menaquinone demethylmenaquinol-6 beta-glucosidase: N(3))-methyltransferase synthase: kdsA FSB75_RS06605 FSB75_RS03980 thiamine- glucosamine 4-hydroxy-2- D-glyceraldehyde hydroxymethyltransferase: diphosphokinase: folK FSB75_RS16355 leuD leuC formyltetrahydrofolate biosynthesis biosynthesis demethylmenaquinol-9 bifunctional pyruvate [1-(2-amino-7-methyl-4-oxo- FSB75_RS18480 RlmH: FSB75_RS10785 [+ 2 isozymes] 1-phosphate panB an N 3 - (2S)-2- L(or D)-ribulose NADPH menaquinol-8 biosynthesis a 5,10- decarboxylase: phosphate oxoglutarate 3-phosphate (2R)-3-sulfolactate 4-guanidinobutanoate uridine bifunctional demethylmenaquinone 7,8-dihydro-3H-pteridin- 1915 KDO-8P 5-phosphate + kinase: thiL aldolase/2- methylpseudouridine isopropylmalate methylenetetrahydrofolate NAD FSB75_RS04220 demethylmenaquinone methyltransferase/2- 6-yl)]ethyl diphosphate dehydro-3-deoxy- XXXG xyloglucan in 23S rRNA demethylmenaquinol-8 NAD(+)/ methyltransferase/2- methoxy-6-polyprenyl- thiamine D-galactopyranose UDP-N-acetyl- phosphogluconate 2-dehydropantoate THMPT oligosaccharide bifunctional NADH kinase: methoxy-6-polyprenyl- 1,4-benzoquinol diphosphate demethylmenaquinol-8 α-D-glucosamine aldolase: demethylmenaquinone FSB75_RS15590 1,4-benzoquinol methylase UbiE: ubiE D-galactonate degradation UDP-N-acetylglucosamine FSB75_RS00210 methyltransferase/2- NAD kinase: methylase UbiE: ubiE menaquinol-6 1-carboxyvinyltransferase: 2,5-diamino-6-(5- XXLG xyloglucan 3-(4- 55 5,6- CTP methoxy-6-polyprenyl- FSB75_RS14100 menaquinol-9 D-galactonate 1-(3-sn-phosphatidyl)- a uridine D-ribofuranose murA phospho-D-ribitylamino) hydroxyphenyl) uroporphyrinogen-III 4-nitrocatecholsulfate dihydrothymine 1,4-benzoquinol NADP + D-glyceraldehyde sn-glycerol 3-phosphate oligosaccharide in tRNA UDP-N-acetyl-α- pyruvate pyrimidin-4(3H)-one pyruvate NAD-dependent dCTP deaminase: methylase UbiE: ubiE 3-phosphate galactonate bifunctional uroporphyrinogen-III tRNA phosphatidylglycerophosphatase sulfatase: dihydropyrimidine ribokinase: FSB75_RS08530 menaquinol-8 D-glucosamine- dehydratase: diaminohydroxyphosphoribosylaminopyrimidine 4-hydroxyphenylpyruvate C-methyltransferase: pseudouridine(55) beta-glucosidase: FSB75_RS06270 dehydrogenase FSB75_RS14790 enolpyruvate dgoD deaminase/5-amino-6-(5-phosphoribosylamino) A: FSB75_RS05895 dioxygenase: hppD cobA synthase TruB: truB FSB75_RS18480 subunit PreA: preA UTP UDP-N- [+ 2 isozymes] uracil reductase RibD: ribD an L-1-phosphatidyl- a pseudouridine 55 D-ribofuranose 5-amino-6-(5-phospho- homogentisate precorrin-2 4-nitrocatechol thymine acetylmuramate D-glucarate 2-dehydro-3-deoxy- sn-glycerol in tRNA 5-phosphate dehydrogenase: degradation II D-ribitylamino)uracil XXXG xyloglucan D-galactonate D-galactopyranose murB 2-dehydro-3- oligosaccharide UDP-N-acetyl- D-glucarate deoxygalactonokinase: α-D-muramate glucarate FSB75_RS00195 4a-hydroxy-N 10 - XLLG xyloglucan 3-phenyl-2- 2'-deoxycytidine dCTP dehydratase: phosphatidylglycerolphosphate an α-limit dextrin 2-hydroxyisobutyramide 5,6-dihydrouracil myo-inositol 2-dehydro-3-deoxy- formyltetrahydrofolate oligosaccharide FSB75_RS10620 (1-oleoyl, 2-palmitoyl) oxopropanoate deoxynucleoside 5-dehydro-4- D-galactonate 4-alpha- NAD-dependent dCTP deaminase: 4a-hydroxytetrahydrobiopterin 4-hydroxyphenylpyruvate amidase: inositol oxygenase: kinase: UDP-N-acetyl- deoxy-D-glucarate 6-phosphate phosphatidylglycerophosphatase glucanotransferase: dihydropyrimidine FSB75_RS08530 dehydratase: FSB75_RS16865 beta-glucosidase: dioxygenase: hppD FSB75_RS06605 FSB75_RS06420 FSB75_RS06550 α-D-muramoyl- A: FSB75_RS05895 FSB75_RS03035 dehydrogenase FSB75_RS18480 a α-limit dextrin [+ 2 isozymes] dUTP L-alanyl-γ-D- 1-oleoyl-2-palmitoyl- an N 10 -formyl- (2-hydroxyphenyl) 2-hydroxy-2- subunit PreA: preA aldehydo-D- with short branches dCMP glutamyl-meso-2,6- phosphatidylglycerol 7,8-dihydrofolate acetate methylpropanoate uracil glucuronate 2,5- D-glyceraldehyde XXXG xyloglucan diaminopimelate pyruvate D-galactopyranose dioxopentanoate 3-phosphate oligosaccharide

2-oxoglutarate a reduced a reduced a reduced plastocyanin plastocyanin plastocyanin an oxidized an oxidized an oxidized plastocyanin D-glucose an amino an inorganic a C4- a C4- plastocyanin a nicotinamide chromate plastocyanin queuosine D-galactose D-gluconate ammonium dicarboxylate acid a lipopolysaccharide anion a polysaccharide a polysaccharide dicarboxylate mononucleotide

cbb3-type cytochrome RS03860 RS00415 RS06070 RS15840 RS08340 RS15600 LptC RS13805 RS15675 RS02680 RS11485 DctA RS20175 CcoN cytochrome c oxidase c oxidase

an inorganic a C4- a C4- a nicotinamide chromate queuosine D-gluconate ammonium an amino mononucleotide a lipopolysaccharide anion a polysaccharide a polysaccharide dicarboxylate dicarboxylate O D-galactose acid 2 O O 2 D-glucose H O 2 2 H O H O 2 2 This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.