Anti-MAP3K13 Monoclonal Antibody, Clone 920DU37.7.2.2 (DCABY-1223) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

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Anti-MAP3K13 monoclonal antibody, clone 920DU37.7.2.2 (DCABY-1223) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.

Specificity Purified His-tagged MAP3K13 protein was used to produced this monoclonal antibody.

Isotype IgM

Source/Host Mouse

Species Reactivity Human

Clone 920DU37.7.2.2

Conjugate Unconjugated

Applications WB

Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Size 400 μl

Preservative 0.09% Sodium Azide

Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Ship Blue ice

Warnings MAP3K13 (LZK) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

GENE INFORMATION

Gene Name MAP3K13 mitogen-activated protein kinase kinase kinase 13 [ Homo sapiens (human) ]

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Synonyms MAP3K13; Mitogen-activated protein kinase kinase kinase 13

Entrez Gene ID 9175

Protein Refseq NP_001229243

UniProt ID O43283

Chromosome Location 3q27

Pathway Insulin Signaling; Integrated Breast Cancer Pathway; MAPK signaling pathway; Signaling events mediated by VEGFR1 and VEGFR2

Function ATP binding; MAP kinase kinase kinase activity; identical protein binding; metal ion binding; protein binding; protein homodimerization activity; protein kinase binding; protein serine/threonine kinase activity

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]