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Home , Higenamine, Hordenine, Octodrine

in Supplements and the Athlete: Necessary or Harmful? November 29, 2017 Today’s Speakers:

Lara Gray, MS, RD, CSSD Anna Filardo, MS, CPT Director of Education Education Program Manager

drugfreesport.com Welcome! Things to note: 1. It is required by the BOC for Certified Athletic Trainers that you are actively present in the live event AND complete the post-webinar survey in order to receive your CEU certificate. 2. CEU certifications (if applicable) will be emailed to attendees no later than Friday, Dec. 1st. 3. Please use the “Questions” box in GoToWebinar. Questions will be reviewed by the moderator and answered at the end. [email protected] Stimulants in Supplements and the Athlete: Necessary or Harmful?

At the end of the presentation, attendees will be better able to: • Recognize common stimulants used as ingredients in dietary supplements. • Outline the potential risks associated with excessive use. • Address energy and performance demands with recommended alternatives to supplement use.

Drug Free Sport, Inc. is approved by the Board of Certification, Inc. to offer continuing education for Certified Athletic Trainers. BOC Certified Athletic Trainers are eligible for 1 Category A CEU for attending this live webinar event. Subscribing Organizations: Tools:

- Dietary Supplement Inquiry - Database - Sports Nutrition Handouts - Athlete Recipes - Mental Health Resources - Supplement Safety Information - Marijuana, Prescription , Alcohol Resources What are Stimulants?

• Performance Enhancing Substances – Cognitive Effects

• Alertness, Attention

• Energy & Exertion – Physiologic Effects

• Elevate blood pressure, heart rate, body temperature

Why Athletes Use Stimulants

• Energy • Focus • Alertness • Poor sleep quality • Delay onset of fatigue • Pre-workout habit High Risk Stimulant Categories

• Weight loss • Pre-workout • Energy drinks Dirty (Baker’s) Dozen Stimulant Ingredients

1. 1,3-DMAA/ 2. 2-aminoisoheptane//DMHA 3. Acacia Rigidula 4. Advantra Z 5. AMP Citrate/4-Amino-2-Methylpentane/DMBA 6. Dendrobium/Nobile Orchid 7. 8. 9. N-Methyl 10. Norcoclaurine/Higenamine 11. …And so many more 12. PEA/Phenylethylamine 13. /Bitter Orange/Citrus Aurantium 1,3-DMAA

• Synthetic stimulant • Potential for hemorrhagic strokes & sudden death • 2012 Banned by the FDA… yet still in dietary supplements

Cohen, P.A., Travis, J.C., Keizers, P.H.J., Duester, P., & Venhuis, B.J. 2017. Four experimental stimulants found in sports and weight loss supplements: 2‐amino‐6‐methylheptane (octodrine), 1,4‐ dimethylamylamine (1,4‐DMAA), 1,3‐dimethylamylamine (1,3‐DMAA) and 1,3‐dimethylbutylamine (1,3‐DMBA). Clinical Toxicology. Retrieved from: http://www.tandfonline.com/doi/full/10.1080/15563650.2017.1398328?scroll=top&needAccess=tru e Cohen, P.A., Travis, J.C., Keizers, P.H.J., Duester, P., & Venhuis, B.J. 2017. Four experimental stimulants found in sports and weight loss supplements: 2‐amino‐6‐methylheptane (octodrine), 1,4‐ dimethylamylamine (1,4‐DMAA), 1,3‐dimethylamylamine (1,3‐DMAA) and 1,3‐dimethylbutylamine (1,3‐DMBA). Clinical Toxicology. Retrieved from: http://www.tandfonline.com/doi/full/10.1080/15563650.2017.1398328?scroll=top&needAccess=tru e /PEA

• Stimulant effects similar to • Potential for tachycardia, anxiety, & agitation • Popular ingredient found in pre-workout and weight-loss supplements Advantra Z®

• Source of synephrine (bitter orange), n-methyl tyramine, hordenine, tyramine, & octopamine

• Thermogenic ingredient

– Commonly used in weight- loss supplements.

• Potential to speed up heart rate and raise blood pressure Excessive Stimulant Side Effects

Caffeine: >400 mg/day Additive Effects

+ +

= Increased Risks FOCUS ON NUTRITION! Why Food…

• Increases energy and mental focus.

• Carbohydrates are fuel for muscles.

• Safe and effective How…

• Adequate total calorie intake • Snacking between meals • Fueling before, during, and after exercise • Maintain hydration throughout the day • Don’t skip the carbs What…

Snacks/Around Exercise Meals • Simple Carbs + Protein + • Complex Carbs + Protein + Fluid Fluid – Peanut butter & jelly – Spaghetti & Meatballs – Instant Oatmeal – Chicken, Rice, & Veggies – Apple/Banana + Peanut – Eggs, toast, & fruit Butter – Yogurt and nuts

Best practice: Work with a Sports Dietitian in your area When…

• Every 2-3 hours • 1-2 hours pre-workout Tips for Increasing Energy with Food

• Do not skip meals • Include foods rich in protein & carbohydrates • Maintain hydration throughout the day Make the time, Take the time…to EAT! 110% in practice gets you nowhere without proper fuel to perform! QUESTIONS?

drugfreesport.com Registration is now open! Program Sessions Covering:

• Generational Differences in Sports 10 Hours of Continuing Education Provided for: • Sleep Science • Mental and Physical Aspects of Injury  Sports Physicians • Working with International Athletes  Athletic Trainers • Performance Anxiety in Athletes • Prescription Opioids in Sport  Sport Psychologists • Prescription Stimulants in Sport • Dietary Supplements – A Sports Industry Update  Sport Dietitians • Marijuana and Sport  Strength and Conditioning Coaches And more!