Reviewers, Volume 6" (1992)

The Editors would like to thank the Carroll, Sean Green, Michael Editorial Board and the following Chaconas, George Greenberg, Michael scientists who were kind enough to Chater, Keith Greenblatt, Jack review papers and provide advice during Chesebro, Bruce Greene, Warner 1992. Your help has been invaluable and Chory, Jo Anne Greenleaf, Amo is greatly appreciated. Clayton, David Greider, Carol Cleveland, Donald Grosschedl, Rudolf Cline, Thomas Gruss, Peter *From November 18, 1991 to November Coen, Enrico Gurdon, John 16, 1992 Cole, Michael Hahn, Steve Collins, Francis Hamlin, Joyce Corces, Victor Hanahan, Doug Aaronson, Stuart Costantini, Frank Harland, Richard Adler, Paul Cox, Michael Harlow, Edward Alt, Fred Crabtree, Gerald Harper, Jeff Altman, Sid Craig, Elizabeth Harrison, Steven Ammeter, Gustav Craig, Nancy Hartenstein, Volker Anderson, David Cullen, Bryan Hartley, David Anderson, Kathryn Curran, Tom Hayday, Adrian Ares, Manuel Darnell, James Hearing, Patrick Amdt, Kim DePamphilis, Mel Helfman, David Amold, Hans Desplan, Claude Hemandez, Nouria Artavanis-Tsakonas, Spyros Devreotes, Peter Herrlich, Peter Ausubel, Fred DiMaio, Dan Hershey, John Baeuerle, Patrick Doe, Chris Herskowitz, Ira Baker, Bruce Donahue, Tom Hieter, Phil Baldwin, Albert Donovan, Peter Hill, Robert Baltimore, David Dunphy, William Hinnebusch, Alan Banerjee, Utpal Driever, Wolfgang Hirsch, Jay Barbacid, Mariano Dynan, Bill Hochstrasser, Mark Beach, David Efstratiadis, Argiris Hopper, Anita Beddington, Rosa Ehrenfeld, Ellie Hopwood, David Beemon, Karen Eichele, Gregor Hovanessian, Ara Beene, Michael Eisenman, Bob Howley, Peter Belfort, Marlene Emerson, Charles Huberman, Joel Bentley, David Engel, Douglas Hudson, Andrew Berk, Arnold Esposito, Rochelle Hughes, Steven Beme, Michael Evans, Ronald Hunter, Tony Betas, Anton Fangman, Walter Hynes, Richard Bemstein, Alan Fanning, Ellen Inouye, Masayori Bienz, Mariann Fedoroff, Nina Ish-Horowicz, David Biggin, Mark Felsenfeld, Gary Jackson, Ian Bingham, Paul Feramisco, Jim Jaeckle, Herbert Bird, Adrian Fields, Stanley Jaenisch, Rudi Bishop, J. Michael Fink, Gerald Jan, Yuh-Nung Bissell, Mina Firtel, Richard Jessell, Thomas Blackburn, Elizabeth Foumier, Keith Johnson, Peter Boeke, Jeff Freeling, Mike Johnson, Alexander Botchan, Michael Friedman, David Jolicoeur, Paul Bothwell, AI Fu, Xin-Yuan Jones, Katherine Bradley, Allan Fuchs, Elaine Joyner, Alex Breeden, Linda Futcher, Bruce Kadesch, Tom Brimacombe, Richard Fyrberg, Eric Kadonaga, James Broach, James Ganem, Don Kaiser, Dale Brockes, Jeremy Gaynor, Richard Kaiser, Kim Brown, Donald Gehring, Walter Karin, Michael Bryant, Peter Gelbart, William Kessin, Richard Buchman, Andrew Gerandakis, Steve Kingston, Robert Burr, Ben Gergen, Peter Kintner, Chris Calame, Kathryn Gilman, Mike Kleckner, Nancy Campbell, Judith Glover, David Klessig, Daniel Capecchi, Mario Goodman, Corey Knowles, Barbara Carey, Michael Gralla, Jay Kolodner, Richard Carlson, Mary Ann Graves, Barbara Konieczny, Stephen

2666 GENES & DEVELOPMENT Komberg, Thomas Reed, Steven Timberlake, William Krainer, Adrian Reeder, Ronald Treisman, Richard Kramer, Angela Reinberg, Daniel Triezenberg, Steven Krasnow, Mark Renkawitz, R. Tye, Bik Krisch, Henry Reznikoff, Bill van der Vliet, Peter Krug, Robert Rheinwald, Jim Van Dyke, Terry Krumlauff, Robb Rigby, Peter van Montagu, Mark Kushner, Sydney Riggs, Arthur Vassali, Jean-Dominique Lamond, Angus Rio, Donald Vennstrom, Bjom Laskey, Ron Roberts, Jeff Verma, Inder Lassar, Andrew Roberts, Jim Voellmy, Richard Leder, Philip Roeder, Robert Vogt, Peter Lehmann, Ruth Rosbash, Michael Wahl, Geoff Leptin, Maria Rose, Mark Walbot, Virginia Levine, Michael Rosen, Craig Walsh, Frank Levy, David Rosenfeld, Geoff Warner, Anne Lichtenstein, Conrad Ross, Jeff Wassarman, Paul Lis, John Rossant, Janet Weinberg, Robert Liu, Leroy Rotter, Varda Weiner, Alan Livingston, David Russell, Paul Weintraub, Harold Lowy, Doug Rutter, William Weissman, Charles Lucas, William Ruvkun, Gary Wessler, Sue Maniatis, Tom Sakano, Hitoshi Westphal, Henry Marlzuff, William Sassone-Corsi, Paolo White, Eileen Martienssen, Rob Schedl, Paul Wickens, Marvin Mathews, Mike Scheres, Ben Wieschaus, Eric McClure, William Scholer, Hans Wilkinson, David McKay, Ron Schupbach, Trudi Willison, Keith McKeown, Mike Segall, Jacqueline Winston, Fred Melton, Doug Sharp, Philip Wolffe, Alan Meyer, Barbara Sherr, Charles Wolgemuth, Deborah Meyerowitz, Elliott Shimkets, L. Woolford, John Mizuuchi, Kiyoshi Shore, David Wormington, Michael Molloy, Peter Silhavy, Tom Wright, Chris Moran, Charles Silver, Lee Wu, Carl Moran, Elizabeth Simon, Melvin Yamamoto, Keith Morris, Ron Smale, Steven Yaniv, Moshe Murray, Andrew Smith, Gerald Yanofsky, Carl Nabel, Gary Smith, Issar Young, Michael Nadal-Ginard, Bemardo Smith, Jim Young, Richard Nevins, Joseph Sollner-Webb, Barbara Zakian, Virginia Newman, Andrew Sonnenberg, Nahum Ziff, Edward Nomura, Masayasu Soriano, Philippe Zipursky, Larry Novick, Richard Spector, David Zucker, Charles Nurse, Paul Spiegelman, Bruce Nusse, Roel Spradling, Alan O'Farrell, Patrick Sprague, George 0liver, Donald Stavnezer, Edward Olson, Eric Stenlund, Ame Oren, Moshe Stemglanz, Roll Orkin, Stuart Steward, Ruth Pabo, Carl Stillman, Bruce Pace, Norman Storb, Urusla Parada, Luis Stragier, Patrick Perlman, Phil Strickland, Sidney Posakony, James Struhl, Gary Prescott, David Struhl, Kevin Preston, Chris Stunnenberg, H. Prives, Carol Surani, Azim Proudfoot, Nick Susskind, Miriam Ptashne, Mark Szostak, Jack Quail, Peter Tatchell, Kelly Racaniello, Vincent Taylor, Michael Rao, N. Tegtmeyer, Peter Rechsteiner, Martin Thomer, Jeremy Reed, Robin Thummel, Carl

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2668 GENES & DEVELOPMENT Author Index, Volume 6 (1992)

Abel, T., 466 Boehmelt, G., 876 Clayton, D.A., 1975 Epner, E.M., 928 Abravaya, K., 1153 Bolado, J., 578 Cleary, M.A., 2058 Eppig, J.J., 1832 Adams, B., 1589 Bonapace, I.M., 1621 Cleary, M.L., 1608 Epstein, C.B., 1695 Adzuma, K., 1679 Bonnez, W., 1131 Cleveland, D.W., 1927 Errede, B., 1293 Atfolter, M., 1082 Borgmeyer, U., 329, 578 Clyman, 1-, 1269 Evans, R., 2258 Aguzzi, A., 1589 Bossy-Wetzel, E., 2340 Cohen, B., 715 Evans, R.M., 329, 578 Aizawa, S., 1821 Bouly, I--P., 1019 Cohen, S.M., 715 Faha, B., 1874 Akizawa, T., 2066 Bouvet, P., 135 Colbert, T., 1940 Falb, D., 454 Alley, M.R.K., 825 Boyer, T.G., 1964 Cole, C.N., 1173 Fangman, W.L., 380 Almir6n, M., 2646 Brandeis, M., 705 Cole, M.D., 166 Feder, J.H., 1402 Alonso-Caplen, F.V., 255 Brannan, C.I., 1832 Coleman, T.A., 745 Feliciello, A., 1621 Alt, F.W., 61, 2248 Braun, T., 888 Colgan, 1., 304 Ferguson-Smith, A.C., 1843 Altman, E., 1165 Bravo, R., 2340 Collins, S.J., 2258 Femandez-Sarabia, M.J., 2417 Amberg, D.C., 1173 Breitbart, R.E., 1783 Cone, K.C., 864 Firtel, R.A., 38 Ammerer, G., 1280 Brill, S.J., 1332 Conlon, R.A., 691 Fisher, P., 2248 Anderson, C.W., 426 Brock, H.W., 223 Cook, A., 1810 Flanagan, P.M., 296 Androphy, E.J., 105 Brody, E., 497 Copeland, N.G., 1832 Foley, K.P., 730 Ariel, M., 705 Broker, T.R., 1131 Corces, V.G., 1865 Fong, T.C., 521 Amdt, K.M., 1319 Brown, D., 2152 Cortese, R., 316 Forrester, W., 1914 Amdt, K.T., 2417 Brown, P.O., 511 Cowie, A., 481 Forrester, W.C., 928 Arnold, H.H., 888 Brown, S.A., 2288 Cross, F.R., 1695 Foumier, R.E.K., 316 Auerbach, B.A., 691, 903 Brown, T.A., 2502 Croston, G.E., 2270 Frank, D., 2112 Awedimento, E.V., 1621 Bruder, J.T., 545 Cullen, B.R., 2077 Franke, A., 1241 Baeuerle, P.A., 2352 Brun, Y.V., 2395 D'Evelyn, D., 2125 Frederickson, R.M., 1631 Baichwal, V.R., 1493 Brunvand, M., 2201 Dahlberg, I.E., 1097 Fresco, L.D., 1386 Baker, B.S., 2569 Bulla, G.A., 316 Datum, K., 2258 Friedel, C., 919 Baker, T.A., 2221 Burke, J.M., 129 Dang., C.V., 81 Friedman, P.N., 1886 Baldwin Jr., A.S., 1899 Busslinger, M., 1589 Darrow, A.L., 1202 Fuchs, E., 1444 Baltimore, D., 775 Butler, G., 93 Dawid, I.B., 356 Fujii, M., 2066 Bang, A.G., 1752 Cairns, B.R., 1305 de la Pompa, J.L., 14 Fujita, T., 775 Bannister, A.I., 1810 Callahan, R., 345 DeArmond, S.J., 1213 Furlong, D., 2646 Bargonetti, J., 1143 Campbell, S., 367 DeCamillis, M., 223 Furukubo-Tokunaga, K., 1082 Bargonetti, 1., 1886 Carey, M., 1716 DeGregori, J.V., 919 Furuya, M., 2364 Barker, D.D., 2312 Carlson, L.L., 2536 DeLoia, J.A., 1190 Gallahan, D., 345 Bartelmez, S., 2258 Carlson, M., 1707 Demeter, L.M., 1131 Gallo, A., 1621 Barton, S.C., 1843 Carpousis, A.J., 149 DePinho, R.A., 1480 Garbi, C., 1621 Baserga, S.I., 1120 Carr, A.M., 2035 DeRobertis, E.M., 591 Gartner, A., 1280 Beckman, D.L., 268 Carroll, S., 2606 DeSimone, V., 316 Gaubatz, S., 568 Bedell, M.A., 1832 Cassano, S., 1621 Dickinson, L.K., 2312 Gauss, G.H., 1553 Beg, A.A., 1899 Casselton, L.A., 568 Dickson, B., 2327 Gehring, W.J., 1030, 1082 Behrendtsen, O., 939 Cedar, H., 705 Dillon, N., 1857 German, M.S., 2165 Behrens, S.-E., 631 Chadwick, R.B., 2165 Dirksen, M.L., 599 Gershon, P.D., 1575 Belasco, J.G., 135 Chaillet, J.R., 1843 Dohrmann, P.R., 93 Geyer, P.K., 1865 Belfort, M., 1269 Chalker, D.L., 117 Dollard, S.C., 1131 Ghosh, S., 775 Bell-Pedersen, D., 2382 Chambard, J.-C., 676 Donahue, T.F., 2463 Giardina, C., 2190 Bellen, H.J., 2125 Chandler, V.L., 864, 2152 Donovan, P.J., 1832 Gillis, S., 61 Benezra, R., 1466 Charron, J., 2248 D6rfler, P., 1589 Gilmore-Herbert, M., 1120 Bennett, M., 1986 Chase, J.W., 2010 Dorland, S., 93 Glazer, L., 1668 Bentley, D.L., 1562 Chasman, D.I., 296 Dubendorff, 1., 2524 Goff, S.A., 864 Benusiglio, E., 1621 Chellappan, S.P., 177 Duckett, C.S., 2352 Goff, S.P., 2248 Benvenisty, N., 2513 Chen, C.-H., 655, 745 Dulic, V., 1874 Gold, L., 497 Berberich, S.J., 166 Chen, L., 81 Dunlap, J.C., 2382 Goldstein, A.L., 1173 Berk, A.J., 1964 Cheng, J., 1444 Dvir, A., 426 Gomer, R.H., 390 Bemstein, P.L., 642 Cheng, N., 223 Dynan, W.S., 426 Good, P.J., 356 Bestor, T.H., 2536 Chiao, P., 2352 Eaton, S., 2635 Gorham, B.I., 2429 Beug, H., 876 Chittenden, T., 953 Ehretsmann, C.P., 149 Gottesman, M.E., 1621 Bhatt, R., 466 Chovnick, A., 367 Eisenman, R.N., 71 G6ttgens, B., 568 Bier, E., 1503, 1728, 2137 Chow, A.M., 1950 Eisenmann, D.M., 1319 Gottschling, D.E., 197 Biere, A.L., 2409 Chow., L.T., 1131 Eltman, 1., 2524 Grabowski, P.J., 2554 Biggin, M.D., 1531 Chu, E., 345 Emerson, B.M., 521 Gralla, J.D., 1716 Bird, A., 876 Chua., N.-H., 2364 Emori, Y., 50, 1005 Graves, B.J., 975 Blackwood, E.M., 71 Chuhjo, T., 2066 Emory, S.A., 135 Green, S.R., 2478 Blundell, P.A., 14 Citron, M., 2409 Engel, J.D., 161, 730 Greene, I.R., 93 Bober, E., 888 Clark, C.D., 2288 Enoch, T., 2035 Gregoriades, A., 568

GENES & DEVELOPMENT 2669 Gross, C.A., 1165 Johnson, D., 1190 Laybourn, P.J., 2270 Meulia, T., 2201 Grossman, S.R., 105 Johnson, F.B., 2177 Lazaris-Karatzas, A., 1631 Meyer, E., 211 Grossniklaus, U., 1030 Johnson, L., 411 Leder, A., 2513 Michaud, S., 1986 Grosveld, F., 1857 Jones, B.A., 380 Leder, P., 29, 2513 Michel, F., 1373 Groudine, M., 928, 2201 Jones, P.A., 1843 Lee, B.-U., 401 Michiue, T., 50, 1005 Grunstein, M., 411 Jonsen, M.D., 975 Lee, G., 61 Miller, B.L., 1770 Gualberto, A., 815 Joseph, S., 129 Lee, H.-s., 284 Miller, K.Y., 1770 Guarente, L., 2001 Joyner, A.L., 691,903 Lee, W.M.F., 81 Miller, S.P., 2463 Gunther, C.V., 975 Ju, Q., 1332 Lee, Y., 1783 Milos, P.M., 991 Guo, Q., 1357 Kadonaga, J.T., 1542, 2270 Lees, E., 1874 Miner, J.N., 2491 Guthrie, C., 2112 Kaelin Jr., W.G., 953 Lehmann, R., 2312 Mitcham, J.L., 788 Habener, J.F., 439 Kafri, T., 705 Lepesant, J.-A., 1019 Mizuuchi, K., 2221 Hadwiger, J.A., 38 Kageyama, R., 2620 Levine, A.J., 1143 Mochizuki, N., 2455 Hafen, E., 2327 Kakizuka, A., 329, 578 Levine, M., 1518, 1728 Moens, C.B., 691 Hahn, S., 1940 Kalfayan, L.J., 233 Lew, D.J., 2021 Montell, D.J., 2299 Halfter, U., 2364 Karin, M., 676 Li, G., 761 Moore, J., 2312 Hanahan, D., 2340 Kato, G.J., 81 Li, L., 676 Morgenbesser, S.D., 1480 Handel, M.A., 1832 Kato, H., 655 Li, S., 401 Morimoto, R.I., 1153 Harm, S.R., 1229 Kay, S., 2364 Lieber, M.R., 1553 Morrow, M.A., 61 Hannah, L.C., 609 Kelleher III, R.J., 296 Lieberman, P.M., 1964 Moss, B., 1575 Hardy, C.F.J., 801 Kelsey, G., 1430 Lin, F.-T., 533 Muhlrad, D., 2100 Harlow, E., 1874 Kerckaert, J.-P., 965 Lin, L., 1071 Mukherjee, B., 1480 Haskill, S., 1899 Kerr, L.D., 2352 Lindahl, L., 2655 Mfiller, M., 1082 Hassell, J.A., 481 Kim, C.G., 928 Lindquist, S., 1402 Murphy, S.P., 1153 Hattori, T., 609 Kim, Y.-J., 2569 Link, A.J., 2646 Musti, A.M., 1621 Hecker, R., 1213 King, D.S., 1950 Lipsick, J., 2524 Mutasa, E.S., 568 Heidecker, G., 545 Kingston, J., 1986 Lis, J.T., 284, 2190 Myers, M.P., 1153 Henze, M., 2021 Kl/imbt, C., 1668 Liu, Y.-1., 1631 Nabel, G., 2352 Hermans-Borgmeyer, I., 578 Klar, A.J.S., 186 Livingston, D.M., 953 Nadal-Ginard, B., 1783 Herr, W., 2058 Klement, J.F., 745 Loomis, W.F., 1058 Naeger, L.K., 1107 Herranz, A.B., 129 Kloter, U., 1082 Lorch, Y., 2282 Nagatani, A., 2364 Herrick, D.J., 642 Knowles, B., 1190 Loros, J.J., 2382 Nakanishi, S., 2620 Heyman, R., 329, 2258 Kojima, T., 50 Lowell, J.E., 2088 Nakata, A., 2214 Hiebert, S.W., 177 Kole, R., 631 Lfihrmann, R., 631 Nasmyth, K., 1280 Higashijima, S.-i., 50, 1005 Kolter, R., 2646 Lund, E., 1097 Nawroz, M., 497 Hirschhom, J.N., 2288 Kooyer, S., 2125 Lfischer, B., 71 Nemeroff, M.E., 255 Hoekstra, M.F., 578 Komberg, R.D., 296, 1305, Luse, D.S., 1342 Nevins, J.R., 177 Hoffman, B.E., 2554 2282 Lyman, S.D., 1832 Nolan, G.P., 775 Holmgren, R.A., 161 Komberg, T.B., 2635 Lynn, A.J., 788 Norris, J.L., 1654 Hopewell, R., 2429 Kosman, D., 1518, 1728 Maddock, I.R., 825 Nurse, P., 2035 Hopkins, N., 1 Kouzarides, T., 1810 Madore, S.J., 2077 Nfisslein-Volhard, C., 619 Horowitz, J.M., 177 Kozmik, Z., 1589 Maeda, T., 2455 Nye, J.A., 975 Hunger, S.P., 1608 Kfiimer, A., 631 Mahdavi, V., 1783 O'Connell, M.L., 1202 Hunter, T., 578 Kranz, R.G., 268 Maher, M., 745 OH, S.-K., 1643 Ikawa, Y., 1821 Krasnow, M.A., 2177 Malim, M.H., 2077 Ohyashiki, K., 1608 Inamdar, M., 367 Kraus, K.W., 284 Malone, C., 2010 Oliviero, S., 1799 Ip, Y.T., 1518, 1728 Krause, H.M., 1740 Malynn, B.A., 2248 Olson, E.N., 676 Ishimaru, S., 50 Kretzschmar, M., 761 Mangelsdorf, D.J., 329 Ong, E.S., 329 Isoda, K., 619 Krisch, H.M., 149 Maniatis, T., 454, 466 Oro, A.E., 329 Isshiki, T., 2455 Kristie, T.M., 2047 Manley, J.L., 304, 1654, 2569 Pabich, E.K., 2463 Iwasaki, H., 2214 Krug, R.M., 255 Manoukian, A.S., 1740 Page, A.W., 2536 Izban, M.G., 1342 Krumm, A., 2201 Marini, N.J., 557 Page, B.D., 1414 Jackson-Grusby, L., 29 Kfies, U., 568 Markiewicz, P., 2010 Palazzolo, M., 367 Jaeger, L., 1373 Kung, H.-f., 1631 Matthews, M.B., 2478 Pan, K.-M., 1213 Jain, R., 390 Kuo, A., 29, 2513 Maurer-Fogy, I., 1589 Panganiban, G., 2606 Jamrich, M., 356, 599 Kuras, R., 1373 McCarrey, J., 705 Parada, L.F., 2235 Jan, L.Y., 2137 Lachance, P., 481 McCarty, D.R., 609 Paranjape, S.M., 2270 Jan, Y.N., 1503, 2137 Lai, J.-S., 2058 McGinnis, W., 1071 Park, A., 1493 Jantzen, H.-M., 1950 Laimins, L.A., 105 McGuffin, M.E., 715 Park, R.E., 1518, 1728 JaramiUo, M.L., 1631 Lambowitz, A.M., 1357 McKeithan, T.W., 2352 Parker, R., 2100 Jeannotte, L., 2248 Lane, M.D., 533 McKnight, S.L., 2502 Parma, D.H., 497 Jegalian, B.G., 591 Lane, W.S., 837 Meisler, M.H., 1457 Paro, R., 1241 Jen, Y., 1466 Laney, J.D, 1531 Meisteremst, M., 761 Pastemak, D., 2592 Jendroska, K., 1213 LaPointe, J.W., 2282 Mendoza, G.E., 848 Patrick, R.M., 815 Jenkins, N.A., 1832 Laurent, B.C., 1707 Merlino, G., 345 Pearson, R.K., 1030 Jhappan, C., 345 Lauter, F.-R., 2373 Messmer, S., 1241 Pedersen, R.A., 939

2670 GENES & DEVELOPMENT Pepinsky, R.B., 105 Roth, S., 619 Smoot, L.B., 1783 Urven, L., 705 P4rez-Riba, M., 2190 Roth, S.Y., 411 Snow, C.M., 1457 Utans, U., 631 Perichon, R., 1019 Rothman-Denes, L.B., 2010 Snyder, M., 497, 1414 Vaessin, H., 2137 Perkins, A.S., 2235 Rothstein, J.L., 1190 Sobolevski, S., 497 Van Doren, M., 2592 Perlman, J., 2125 Ruben, S.M., 745, 1899 Solomon, J., 1402 Vasil, I.K., 609 Perrimon, N., 1503 Rudner, D.Z., 2088 Solomon, N., 1402 Vasil, V., 609 Petersen, J.M., 975 Ruley, H.E., 919 Solter, D., 1190 Verma, I.M., 667, 2352 Peterson, S.R., 426 Ruppert, S., 1430 Sonenberg, N., 1631 yon Melchner, H., 919 Pfeifle, C., 715 Russo, V.E.A., 2373 Sontheimer, E.J., 2542 Walker, K., 1143 Pick, L., 1082 Rutledge, B.J., 1503 Spiegelman, B.M., 1799 Walsh, K., 815 Pierre, D., 223 Rutter, W.J., 2165 Spotts, G.D., 1229 Wampler, S.L., 1542 Pintel, D.J., 1107 RCrth, P., 2299 Spradling, A.C., 2443 Wamsley, P., 2352 Pognonec, P., 655 Sachs, A.B., 2088 Sprague Jr., G.F., 1293 Wang, C., 2312 Pomerantz, J.L., 2047 Saga, Y., 1821 Sprenger, F., 2327 Wang, J., 2165 Ponticelli, A.S., 296 Saigo, K., 50, 1005 Springer, M.L., 1052 Wang, W., 1716 Posakony, J.W., 1752, 2592 Sakakura, T., 1821 Stahle, C., 345 Wasylyk, B., 965 Powell, P.A., 2592 Salds, F.J., 1202 Stanton, B.R., 2235 Wasylyk, C., 965 Prakash, S.S., 105 Samuelson, L.C., 1457 Steinhauer, W.R., 233 Wegner, J., 591 Prendergast, G.C., 2429 Sandmeyer, S.B., 117 Steitz, J.A., 2542 Weintraub, H., 1466 Prescott, D.M., 788 Sandri-Goldin, R.M., 848 Sternglanz, R., 1332 Werb, Z., 939 Prives, C., 1143, 1886 Sarnow, P., 1643 Stevenson, B.J., 1293 Westerfield, M., 591 Prokipcak, R.D., 642 Sasai, Y., 2620 Stewart, V., 2248 Westhof, E., 1373 Prusiner, S.B., 1214 Sasaki, H., 1843 Stillman, D.J., 93 Whittaker, L., 2524 Purton, T., 1562 Sassoon, D.A., 2235 Stockhaus, J., 2364 Wickens, M., 1914 Piischel, A.W., 591 Savant-Bhonsale, S., 1927 Stolk, J.A., 837 Wieschaus, E., 1255 Qin, X.-q., 953 Sawa, H., 244 Strickland, S., 1202 Wild, J., 1165 Qiu, Y., 255 Schedl, A., 1430 Strouboulis, J., 1857 Wilson, J.L., 1131 Radicella, J.P., 2152 Scheidereit, C., 761 Struhl, K., 296, 1799 Winston, F., 1319, 2288 Raghavan, V., 367 Scheinman, R.I., 1899 Sturm, K.S., 939 Wisdom, R., 667 Ramer, S.W., 1305 Schmid, E., 1430 Stutz, F., 1914 Wolfner, M.F., 284 Rapp, U.R., 545 Schmitt, M.E., 1975 Sugimoto, K., 2021 Wright, J.H., 197 Rappolee, D.A., 939 Schoborg, R.V., 1107 Sumimoto,.H., 655 Wu, J., 1770 Rashid, D., 667 Schreiber, H., 1444 Surani, M.A., 1843 Wyatt, J.R., 2542 Raybum, H., 919 Schultz, G.A., 939 Sussel, L., 801 Xin, J.-H., 481 Razin, A., 705 Schultz, M.C., 1332 Sutherland, J.A., 1810 Xu, M.-Q., 1373 Reddy, S., 919 Schuster, H., 2409 Sutton, A., 2417 Yagi, T., 1821 Reed, R., 1986 Schfitz, G., 1430 Tabata, T., 2635 Yamamoto, K.R., 2491 Reed, S.I., 557, 1874, 2021 Scott, M., 1213 Tagawa, Y., 2620 Yamamoto, M., 2455 Reeder, R.H., 1332 Scott, M.P., 1643 Taira, M., 356 Yancopoulos, G.D., 61 Reichman, R.C., 1131 Sebastian, B., 578 Takahagi, M., 2214 Yang, S.-L., 1213 Reik, W., 1843 Segal, D., 715 Tamai, K., 93 Yang, X.W., 1120 Resnick, J.L., 1832 S4galat, L, 1019 Taphouse, C.R., 390 Yanofsky, C., 1052, 2373 Reynisdottir, I., 1886 Seiki, M., 2066 Taraboulos, A., 1213 Yazdanbakhsh, K., 1518 Rhodes, N., 1293 Selegue, J., 2606 Tassan, J.-P., 2580 Yen, J., 667 Richardson, D.L., 1058 Shapiro, L., 825, 2395 Teng, M., 1444 Yoon, H., 2463 Richardson, H., 2021 Sharp, P.A., 2047 Tessarollo, L., 2235 Younger-Shepherd, S., 2137 Richardson, W.V.J., 568 Shemer, R., 705 Thiele, D.J., 93 Yu, Q.-C., 1444 Richter, J.D., 2580 Shigemoto, R., 2620 Thies, E., 1430 Yu, Y.-T., 1783 Ricupero, S.L., 1319 Shilo, B.-Z., 1668 Tihy, F., 1373 Yue, L., 2443 Rio, D.C., 1386 Shimizu, M., 411 Tiley, L.S., 2077 Yuen, I.S., 390 Roberts, S., 1562 Shimkets, L.J., 401 Ting, C.-N., 1457 Yura, T., 1165 Robertson, E.J., 2248 Shimura, Y., 244 Tjian, R., 1493, 1950 Zahler, A.M., 837 Robinson, G.S., 1799 Shinagawa, H., 2214 Tolar, L.A., 2152 Zakian, V.A., 197 Rodrigues, V., 367 Shore, D., 801 Torchia, M., 1213 Zambetti, G.P., 1143 Roeder, R.G., 655, 761 Shub, D.A., 1373 Toyama, K., 1608 Zaret, K.S., 991 Ron, D., 439 Siebel, C.W., 1386 Trawick, D.R., 268 Zeller, R., 14 Rooney, J.W., 1319 Simon, R., 2580 Trumpp, A., 14 Zengel, J.M., 2655 Rosbash, M., 1914 Simpson, R.T., 411 Tsai, S., 2258 Zhang, K., 1503 Rose, L.S., 1255 Singh, J., 186 Tsuchihashi, Z., 511 Zhang, Q., 2352 Rosen, C.A., 655, 745, 1899 Singson, A., 2592 Tsuchiya, H., 2066 Zhao, Q., 1107 Rosenberg, M.P., 1457 Skames, W.C., 903 Tullis, G.E., 1107 Zhong, T., 2417 Rosenkrans, L., 609 Skeath, J., 2606 Turcotte, B., 2001 Zhou, J.Y., 329 Ross, J., 642 Skowronski, J., 1190 Turksen, K., 1444 Zhou, Q., 1964 Rossant, J., 1, 691 Sloan-Brown, K., 1229 Tymon, A.M., 568 Ziff, E.B., 2429 Rossi, J.M., 1402 Smith, G.H., 345 Ulrich, E., 876 Zuo, P., 2569 Roth, M.B., 837 Smith, M.R., 1631 Urb~inek, P., 1589

GENES & DEVELOPMENT 2671 Subject Index, Volume 6 (1992)

mediated by group I intron core Axis (Michel et al.), 1373-1385 formation, X. laevis, blastopore lip- Abdomen formation, Drosophila, role of mouse ld locus (Jackson-Grusby et al.}, specific gene IDirksen et al.), Pumilio and Nanos activity 29-37 599--608 (Barker et al.), 2312-2326 3' splice site choice in yeast (Frank and -patterning genes, Drosophila [Skeath Abscisic acid (ABA), maize seed matura- Guthrie), 2112-2124 et al.), 2606-2619 tion, C1 gene activation (Hat- U1 snRNP interaction with 3' splice tori et al.), 609--618 site factor U2AF65 (Hoffman B ACE2, yeast transcriptional activator and Grabowski), 2554-2568 B-cell differentiation, BSAP expression (Dohrmann et al.), 93-104 Amino acid (methionine) deprivation, (Adams et al.I, 1589-1607 achaete (ac) Drosophila gene and translational control (Hann b-HLH proteins, Drosophila, interaction auto- and cross-regulatory activities et al.), 1229-1240 with dl morphogen (Ip et al.), antagonized by emc gene (Van Ankyrin repeats, of GABPB, interaction 1728-1739 Doren et al.), 2592-2605 with GABPa (Brown and Me- Bacteriophage h, Rex-mediated cell controlled by axis patterning genes Knight), 2502-2512 death (Parma et al.}, 497-510 (Skeath et al.), 2606-2619 Antennapedia mRNA, Drosophila ho- Bacteriophage T4 Acidic activation domain, of VP16 (Tiley meotic gene, internal ribosome gene 32, RNase E's role in mRNA pro- et al.), 2077-2087 binding (OH et al.I, 1643-1653 cessing (Ehretsmann et al.), Acidic activator, GAL4-AH (Wang et al.), Anthocyanin 149-159 1716-1727 biosynthesis, maize seed maturation sunY intron (Michel et al.), 1373-1385 Activation domain, conserved motifs in (Hattori et al.), 609--618 Bacteriophages P1 and P7, antisense in- Fos and lun (Sutherland et al.), pigmentation pathway, maize (Goff et hibition in immI region (Biere 1810-1819 al.), 864-875 et al.), 2409-2416 Activator region, cell-type-specific, of production, distinct tissue specifici- Bar homeo box genes, Drosophila X c-Jun (Baichwal et al.), 1493- ties determined by allelic diver- chromosome, BarH1 and BarH2 1502 sity of maize B gene (Radicella (Higashijima et al.}, 1005--1018 Adducin, role in Drosophila life cycle et al.), 2152-2164 Bar region, Drosophila eye development, (Yue and Spradling), 2443-2454 Antirepressor, product of ant gene in dual homeo box genes (Higashi- Adenovirus E la protein, inhibition of bacteriophage Pl and P7, syn- jima et al.), 50-60 myogenic differentiation (Braun thesis repressed by c4 gene Basic helix-loop-helix proteins, Droso- et al.), 888-902 product (Biere et al.), 2409-2416 phila ac and sc (Van Doren et Adh gene Antisense inhibition, immI region of al.), 2592-2605 Drosophila and man, conserved regu- bacteriophages Pl and P7 (Biere bcl-3 proto-oncogene, encodes IKB pro- latory unit (Falb and Maniatis), et al.), 2409-2416 tein (Kerr et al.), 2352-2363 454-465 AP-I 13-globin fat body-specific enhancers, CREB/ binding site, of oncogene-responsive gene ATF binding to (Abel et al.), element (Bruder et al.}, 545-556 chick, role of erythroid-specific en- 466-480 family of regulatory proteins, c-Jun hancer binding factor cGATA-1 Adipocyte-specific genes, transcription (Baichwal et al.), 1493-1502 {Fong et al.), 521-532 activation by C/EBP (Lin and interaction with glucocorticoid recep- human, homologous recombination Lane), 533-544 tor at composite receptor ele- into LCR (Kim et al.), 928-938 AEF-1, competitive binding with C/EBP ment (Miner and Yamamoto), locus, human, developmental regula- (Falb and Maniatis), 454-465 2491-2501 tion of in transgenic mice Albino-deletion complex, mice (Ruppert transcription factors, and cellular (Stouboulis et al.), 1857-1864 et al.), 1430-1443 transformation (Oliviero et al.), bHLH domain, of Myf-5, target of inhibition Albumin promoter, mouse liver tissue, 1799-1809 by Ela (Braun et al.), 888-902 transcription complexes on (Mi- Aspergillus nidulans, cell pattern forma- motif, maize transcriptional activa- los and Zaret), 991-1004 tion and StuA gene (Miller et al.), 1770-1782 tors, B and R (Golf et al.), 864- alf/hsdr-I region, lethal albino mice 875 (Ruppert et al.}, 1430-1443 Attenuation E. coli S10 operon (Zengel and Lin- Bicoid (bcd) morphogen, and stripes in Allelic diversity, of maize B regulatory dahl), 2655--2662 Drosophila embryo (Ip et al.), gene (Radicella et al.), 2152- N-myc (Morrow et al.), 61-70 1728-1739 2164 Attenuation/termination. See Termina- Biogenesis, bacterial cytochrome c oq-Antitrypsin gene, extinction of (Bulla tion/attenuation. (Beckman et al.}, 268-283 et al.), 316-327 Autogenous control mechanism, E. coli Biphasic effect, of Max on Myc cotrans- a 2 repressor, and nucleosome position- r-protein L4 regulates S10 op- formation activity (Prendergast ing (Roth et al.), 411-425 eron (Zengel and Lindahl), et al.), 2429-2439 Alternative pre-mRNA splicing, model 2655-2662 Blastopore lip, Xenopus, axis formation for mechanism (Siebel et al.), AUUUA motifs, and mRNA instability (Dirksen et al.), 599--608 1386-1401 (Savant-Bhonsale and Cleve- Blue light inducible gene, N. crassa, bli-7 Alternative splicing land), 1927-1939 is eas gene (Lauter et al.), 2373- Drosophila otu transcript (Steinhauer Avian cells, telomere binding-protein 2381 and Kalfayan), 233-243 MF3 (Gualberto et al.), 815-824 Bovine papillomavirus transgenic mice,

2672 GENES & DEVELOPMENT fibrosarcoma development {Bos- transcription factor, CHOP inhibits Cellular transformation, and GCN4 and sy-Wetzel et al.), 2340-2351 function (Ron and Habener), AP- 1 transcription factors {Oliv- Branch migration, promoted by RuvA- 439-453 iero et al.), 1799-1809 RuvB interaction with Holliday C1 complex, HSV, Oct-1 POU domain is Cellularization, Drosophila, hullo gene junction (Iwasaki et al.), 2214- recognized by VP16 (Pomerantz (Rose and Wieschaus), 1255- 2220 et al.), 2047-2057 1268 breathless (btl), Drosophila FGF receptor c4 antisense repressor, transcriptional Chaperones, SecB, E. coli protein export homolog, and cell migration control via translational repres- (Wild et al.), 1165-1172 (Kl~imbt et al.), 1667-1678 sion {Biere et al.), 2409-2416 Checkpoint genes, S. pombe, coupling of BRF1, a TFIIB-related factor involved in Cachexia, and TNFa expression in trans- mitosis to completion of DNA RNA Pol III transcription (Col- genie mice (Cheng et al.), 1444- replication (Enoch et al.), 2035- bert and Hahn), 1940-1949 1456 2046 BSAP, paired domain transcription fac- cAMP production, and S. pombe gpa2 Chemoreceptor, bacterial, polar localiza- tor, homology between mouse gene (Isshiki et al.), 2455-2462 tion of {Alley et al.), 825-836 and man (Adams et al.), 1589- Carboxy-terminal domains, role in nega- Chicken cell lines, immortalization (Ul- 1607 tive regulation (Dubendorff et rich et al.], 876-887 Budding yeast, Saccharomyces cerevi- al.), 2524-2535 Chicken limb deformity (ld) gene, nu- siae, in vivo DNA methylation CArG boxes, of p67 sRF binding factor, in- clear proteins encoded by by foreign methylases as probe teraction with Taxi {Fujii et al.), {Trumpp et al.), 14-28 for chromatin structure (Singh 2066-2076 CHOP, nuclear protein, dominant-nega- and Klar), 186-196 Casein kinase II (CKII), Max DNA-bind- tive inhibitor of transcription bZIP fusion protein, Hlf, altered proper- ing activity inhibited {Berberich (Ron and Habener), 439--453 ties in acute leukemia (Hunger and Cole), 166-176 Chromatin et al.), 1608-1620 Caulobacter binding, role of Pc chromo domain polar localization of chemoreceptor (Messmer et al.), 1241-1254 (Alley et al.), 825-836 C protein, encoded by Drosophila ph polar morphogenesis and cell division, gene (DeCamillis et al.I, 22,3- C signal, CsgA gene product entrains sigma s4 required (Brun and Sha- 232 Myxococcus development (Li et piro), 2395-2408 structure al.), 401-410 cdc25 homolog, mouse, Cdc25M2 (Kak- budding yeast {Singh and Klar}, 186- c-Jun, cell-type-specific activator region, izuka et al.), 578-590 196 two regulatory domains {Baich- Cdc28 kinase, activation of by Clb pro- human ~-globin gene [Kim et al.), wal et al.), 1493-1502 teins {cyclin-B homologs)(Rich- 928-938 c-Myb, carboxy-terminal elements of, ardson et al.), 2021-2034 and mRNA processing [Forrester et negative regulation (Dubendorff cDNA libraries, preimplantation mouse al.1, 1914-1926 et al.), 2524-2535 development (Rothstein et al.), nucleosome positioning (Roth et c-myc 1190-1201 al.), 411--425 modulating action, gene target of Cds28 kinase, Saccharomyces cerevi- S. cerevisiae, alteration of by SNF (ECA39) (Benvenisty et al.), siae, transcriptional activation proteins (Laurent and Carlson), 2513--2523 of Gl-specific genes (Marini and 1707-1715 regulatory interaction with N-myc Reed), 557-567 S. cerevisiae, telomeric and subtelo- (Stanton et al.), 2235-2247 Cell cycle meric (Wright et al.), 187-210 mRNA, stability (Bernstein et al.), cyclin E/E2F association (Lees et al.), and transcription (Hirschhom et al.), 642-654 1874-1885 2288-2298 see also myc gene. Saccharomyces cerevisiae, cyclin-B c-Myc, hetero-oligomerization to Max homologs function in S phase and transcriptional activity (Croston required for function {Kato et and in G 2 (Richardson et al.], et al.), 2270-2281 al.), 81-92 2021-2034 templates, transcription initiation in c-rnyc (human) gene expression, block- S. pombe, checkpoint genes (Enoch et yeast RNA polymerase tran- ing of transcriptional elongation al.), 2035-2046 scription system (Lorch et al.), (Krumm et al.), 2201-2213 Cell death, Rex-mediated (Parma et al.), 2282-2287 c-myc 1, translational activation of 497-510 of mouse Igf2 gene, and parental im- (Hann et al.), 1229-1240 Cell fate, Drosophila printing (Sasaki et al.), 1843- C/EBP eye development (Higashijima et al.), 1856 competitive binding with AEF-1 (Falb 5O-60 Chromo domain, evolutionary conserva- and Maniatis), 454--465 H gene controls SOP cell fate (Bang tion (Messmer et al.), 1241- contains HOB2 activation domain and Posakony), 1752-1769 1254 {Sutherland et al.), 1810-1819 Cell growth, aberrant induction of Chromosomal translocations, leukomo- Drosophila and mammalian, func- HTLV-1 immediate early genes genesis (Hunger et al.), 1608-1- tional and structural similarity {Fujii et al.), 2066-2076 620 (RCrth and Montell), 2299-2311 Cell migration, Drosophila, role of FGF Chromosome segregation, yeast, genes mechanism of action (Milos and Za- receptor homolog (breathless) involved in (Page and Snyderl, ret), 991-1004 (Klfimbt et al.), 1667-1678 1414-1429 role of during differentiation of 3T3-L 1 Cell-type-specific activator region, c-Jun, CIK1, yeast, SPB-associated protein preadipocytes (Lin and Lane), two regulatory domains (Baich- {Page and Snyder), 1414-1429 533-544 wal et al.}, 1493--1502 Circadian clock, N. crassa ccg-2 gene, in-

GENES & DEVELOPMENT 2673 teracting role with light (Bell- Cytochrome c, bacterial biogenesis domain, of AP-1 (Miner and Ya- Pedersen et al.), 2382-2394 (Beckman et al.), 268-283 mamoto), 2491-2501 Clb proteins, cyclin-B homologs from Cytoplasmic element, wild-type p53-specific yeast, role during mitosis (Rich- bridges (ring canals), Drosophila oo- (Zambetti et al.), 1143-1152 ardson et al.), 2021-2034 genesis (Yue and Spradling), and ets family members (Wasylyk et CLB5 novel B cyclin, Saccharomyces 2443--2454 al.), 965-974 cerevisiae, role in S phase (Ep- inhibitory protein, IKB, interaction factor, terminator-binding factor stein and Cross), 1695-1706 with NLS of NF-KB {Beg et al.), {TBF I)(Roberts et al.), 1562- CMF (conditional medium factor), Dic- 1899-1913 1574 tyostelium density-sensing mech- polyadenylation, regulation of murine inhibition of wild-type p53 binding anism (Jain et al.), 390--400 maternal mRNAs (Sall4s et al.}, (Bargonetti et al.), 1886-1898 Cofactors, interaction with yeast HAP1 1202-1212 protein, C/EBP {RCrth and Montell), DNA-binding domain (Turcotte retention, mechanism of action (Beg et 2299-2311 and Guarente), 2001-2009 al.}, 1899-1913 protein, Dps, regulatory and protec- Coliphage N4, double-stranded DNA vi- tive roles in starved E. coli rus, early promoter activation (Almir6n et al.), 2646-2654 by supercoiling and SSB (Mark- D protein, papillomavirus E2 protein iewicz et al.), 2010-2019 DAI, double-stranded RNA-activated (Prakash et al.), 105-116 Composite response element, plfg, AP-1 protein kinase, RNA-binding proteins, ets gene family (Nye et al.), and glucocorticoid receptor in- motifs in (Green and Mathews), 975-990 teraction (Miner and Ya- 2478-2490 of Rel protein {Kerr et al.), 2352- mamoto), 2491-2501 Deadenylation 2363 con gene expression, N. crassa sporula- of MFA2 yeast transcript (Muhlard and melting, late step in transcription ini- tion pathway (Springer and Parker), 2100-2111 tiation pathway {Wang et al.), Yanofsky), 1052-1057 yeast, 3'-UTR-dependent (Lowell et 1716----1727 Cone cell formation, Drosophila, dual al.), 2088-2099 methylation Bar homeo box genes (Higashi- Dedifferentiation of thyroid cells, v-Ras in vivo, of yeast genes by foreign me- jima et al.), 50-60 and PKC down-regulated nu- thylases (Singh and Klar), 186- Conidia, N. crassa (Lauter et al.), 2373- clear PKA {Gallo et al.), 1621- 196. 2381 1630 and parental imprinting of mouse Conidiation, A. nidulans, cell pattern Deletional vs. inversional V(D)J recom- Igf2 gene (Sasaki et al.}, 1843- formation (Miller et al.), 1770- bination, (Gauss and Lieber), 1856 1782 1553-1561 see also methylation. Conserved regulatory unit, Drosophila, Density-sensing mechanism, Dictyoste- methyltransferase (DNA MTase), in Adh gene (Falb and Maniatis), lium (Jain et al.), 390--400 preimplantation mouse em- 454-465 Developmental mutations, Paramecium bryos (Carlson et al.), 2536- Coprinus cinereus, A mating-type gene primaurelia, microinjection of 2541 complexes (Kfiues et al.), 568- telomeric gene (Meyer), 211- processing, O. nova gene scrambling 577 222 (Mitcham et al.}, 788-800 Couch potato {cpo) gene, Drosophila Developmental systems (Holmgren and repair, yeast, role of SSL1 gene product PNS functioning (Bellen et al.), Engel), 161-165 (meeting re- {Yoon et al.), 2463-2477 2125-2136 view) replication, completion of coupled to CREB/ATF transcriptional regulatory Dfd homeotic protein, Drosophila, func- mitosis, role of fission yeast proteins, BBF-2 (Abel et al.), tional specificity (Lin and genes IEnoch et al.), 2035-2046 466--480 McGinnis), 1071-1081 synapsis, molecular mechanism of CsgA gene product, Myxococcus devel- Dictyostelium (Adzuma), 1679-1694 opment {Li et al.), 401-410 development, density-sensing factor CTS1 gene, yeast, regulation by ACE2 (Jain et al.), 390--400 transposition, phage Mu (Baker and {Dohrmann et al.), 93-104 G~ protein function (Hadwiger and Fir- Mizuuchi), 2221-2232 Culmination, Dictyostelium sporulation tel), 38-49 virus, coliphage N4 [Markiewicz et (Richarson and Loomis), 1058- sporulation, disruption of and spore al.), 2010-2019 1070 instability (Richardson and DnaJ heat shock protein, role in E. coli Cyclin E, association with E2F transcrip- Loomis}, 1058-1070 protein export (Wild et al.), tion factor (Lees et al.), 1874- Dimerization, papillomavirus E2 protein 1165-1172 1885 (Prakash et al.), 105-116 DnaX gene, E. coli, translational frame- Cyclin, S. cerevisiae, role of CLB5 in S DNA shifting {Tsuchihashi and phase (Epstein and Cross), binding Brown), 511-519 1695-1706 activity, CKII inhibits Max ho- Dominant interference, Myc/Max onco- Cyclin-B homologs (Clb proteins, Sac- modimers (Berberich and Cole), genie mechanisms (Mukherjee charomyces cerevisiae, func- 166-176 et al.), 1480-1492 tion in S phase and in G2 (Rich- complex, GABP (Brown and Mc- Dominant-negative ardson et al.), 2021-2034 Knight), 2502-2512 activity, mutant RAR~ against normal Cyclin/kinase complexes, regulation of complex, Max:c-Myc (Kato et al.), RAR~ (Tsai et al.), 2258-2269 E2F during different phases of 81-92 inhibitor (CHOP), of transcription fac- cell cycle (Lees et al.), 1874- complex Myc:Max (Blackwood et tors of C/EBP and LAP (Ron and 1885 al.), 71-80 Hbener), 439-453

2674 GENES & DEVELOPMENT Dorsal (dl) Drosophila morphogen nonessential zeste gene, activates Ubx of proneural clusters (Van nuclear transport established by sig- promoter (Laney and Biggin), Doren et al.), 2592-2605 naling pathway (Norris and 1531-1541 Dynamin, GTP-binding domain {Jones Manley), 1654-1667 oogenesis, hts gene encodes homolog and Fangman}, 380-389 functional domains of (Isoda et al.), of adducin (Yue and Spradling}, 619-630 2443-2454 initiates rhomboid (rho) stripes (Ip et ovarian development, otu mutations al.), 1728-1739 (Steinhauer and Kalfayan), 233- E proteins, association with Id, inhibi- dorsal-twist interaction, Drosophila 243 tion of muscle differentiation mesoderm, snail gene expres- P-element splicing iSiebel et al.), (Jen et al.), 1466-1479 sion (Ip et al.), 1518-1530 1386-1401 E2a gene, chromosomal translocations Dorsal-ventral, polarity, Drosophila em- Pc chromo domain, functional role of in acute leukemias {Hunger et bryo, nuclear transport of dl (Messmer et al.), 1241-1254 al.), 1608-1620 {Norris and Manley), 1654-1667 pair-rule gene eve protein functions E2F transcription factor Dorso-ventral axis formation, Droso- as concentration-dependent mor- and RB {Qin et al.), 953-964 phila, role of spitz gene {Rut- phogen (Manoukian and Krause), association with cyclin E [Lees et al.I, ledge et al.), 1503-1507 1740-1751 1874-1885 Double-stranded RNA pan-neural gene (dpn) with HLH motif interaction with pRB {Hiebert et al.), -activated protein. See DAI. (Bier et al.), 2137-2151 177-185 and activation of DAI {Green and PNS, couch potato protein, homology eas N. crassa gene Mathews), 2478-2490 to RNA-binding proteins {Bel- allelism with ccg-2 (Bell-Pedersen et Dps DNA-binding protein, regulatory len et al.), 2125-2136 al.), 2382-2394 and protective roles in starved polyhomeotic gene (ph), encodes chro- structural gene for the rodlet protein E. coli (Almir6n et al.), 2646- matin protein (DeCamillis et (Lauter et al.), 2373-2381 2654 al.), 223-232 ECA39 gene, target gene of c-Myc regu- Drosophila position-specific transcriptional re- lation (Benvenisty et al.), 2513- abdomen formation, role of Pumilio pression (Geyer and Corces), 2523 and Nanos activity {Barker et 1865-1873 eIF-4E-induced transformation, medi- al.), 2312-2326 pqp gene is wings down {WDN) gene ated by Ras signaling pathway Adh gene, conserved regulatory unit (S4galat et al.), 1019-1029 {Lazaris-Karatzas et al.), 1631- within man (Falb and Maniatis), preIC assembly, differential regulation 1642 454--465 of by UBX and EVE (Johnson Elongation factor C/EBP, functional and structural sim- and Krasnow), 2177-2189 SII, facilitates transcript cleavage ilarity to mammalian C/EBP promoter-paused RNA pol II (Giardina {Izban and Luse), 1342-1356 (Rerth and Montell), 2299-23 11 et al.), 2190-2200 TFIIF, interaction with Tat {Kato et cell migration, role of breathless (btl), proneural gene expression (Skeath et al.), 655-666 an FGF receptor homolog al.), 2606-2619 Embryogenesis {KIambt et al.), 1667-1678 relationship between engrailed (en) Drosophila, C/EBP required for devel- cellularization, hullo gene (Rose and and hedgehog (hh) (Tabata et opment (Rerth and Montell), Wiecschaus), 1255-1268 al.), 2635-2645 2299-23 11 dorsal morphogen RNA polymerase pausing on hsp70 (Holmgren and Engel), 161-165 {meet- initiates rhomboid stripes {Ip et al.), (Lee et al.), 284-295 ing review) 1728-1739 RNA-binding protein RBP1, func- mouse, DNA methylation {Kafri et nuclear transport (Norris and Man- tional similarity to human al.), 705-714 Icy), 1654-1667 splicing factor ASf/SF2 (Kim et TN-deficient mice develop normally external sensory (es) organs, subtype al.), 2569-2578 (Saga et al.), 1821-1831 determination (Higashijima et scalloped (SD) gene encodes evolu- Embryonal stem cells, gene disruption al.), 1005-1018 tionarily conserved transcrip- by promoter trap vectors (yon eye development, prepattern in (Dick- tion factor {Campbell et al.), Melchner et al.), 919-927 son et al.), 2327-2339 367-379 Embryonic ftz homeo domain, helix-turn-helix sensory organ development, Hairless development, vertebrate, mutational motif (Furukubo-Tokunago et gene (H), protein controls alter- analysis of (Rossant and Hop- al.), 1082-1096 native cell fate (Bang and Posa- kins), 1-13 {Review) hairy and Enhancer of split, rat HLH kony), 1752-1769 lethality, loss of N-myc function proteins HES-1 and HES-3 are sloppy paired locus, segmentation (Charron et al.), 2248-2257, structurally related to (Sasai et (Grossniklaus et al.), 1030-1051 (Stanton et al.], 2235-2247 al.), 2620-2634 spitz gene, encodes putative EGF-like stem (ES) cells, gene trap approach in homeo box genes, dual Bar genes (Hi- growth factor {Rutledge et al.), {Skames et al.}, 903-918 gashijima et al.), 50--60 1503-1507 Endoribonuclease homeo domain functional specificity TFIID-promoter interactions {Colgan RNase E, E. coli, specificity of (Ehrets- (Lin and McGinnis), 1071-1081 and Manley), 304-315 mann et al.), 149-159 hsp70 expression at normal tempera- transcription factor IIB {dTFIIB) (Warn- RNase MRP, nuclear role of (Schmitt ture {Feder et al.), 1402-1413 pier and Kadonaga), 1542-1552 and Clayton), 1975-1985 mesoderm, doral-twist interactions, transcriptional activator, CREB/ATF engrailed {en) Drosophila gene, regulates snail gene expression (Ip et al.), family (Abel et al.), 466-480 expression of hh {Tabata et al.), 1518-1530 wing imaginal disc, spatial patterning 2635-2645

GENES & DEVELOPMENT 2675 Enhancer of split [E(spl)], Drosophila, rat dent morphogen (Manoukian Formins, ld alternatively spliced tran- HLH proteins HES-1 and HES-3 and Krause), 1740-1751 script protein products (Jack- are structurally related to (Sasai Drosophila, homeo domain protein son-Grusby et al.), 29-37 et al.}, 2620-2634 EVE (Johnson and Krasnow), Fos Enhancer-binding factors, counteract 2177-2189 and muscle transcription, repression chromatin-mediated repression Evolution of gene regulation, role for ret- of (Li et al.), 676-689 (Croston et al.}, 2270-2281 rotransposition (Ting et al.), oncoprotein, HOB motifs of (Suther- Enhancers. See also Promoter-enhancer 1457-1465 land et al.), 1810-1819 interaction. Evolutionary conservation see also oncoproteins Epidermal growth factor [EGF), Droso- transcription factors (Campbell et al.), FosB protein, transactivation domain phila spitz gene encodes puta- 367-379 missing in FosB2 (Wisdom et tive homologous protein (Rut- vertebrate limb pattern formation al.), 667--675 ledge et al.), 1503-1507 {Trumpp et al.), 14-28 FosB2 protein, lacks transactivation do- Escherichia coli Exon main present in FosB (Wisdom branch migration, promoted by RuvA definition, effect of nonsense muta- et al.), 667--675 and RuvB proteins (Iwasaki et tions on (Naeger et al.), 1107- Fumaryl acetoacetate hydrolase, gene for al.), 221 4-2220 1119 within al[/hsdr-1 region, lethal endoribonuclease RNase E, specificity selection, positive regulation by U1 albino mice (Ruppert et al.), of (Ehretsmann et al.}, 149-159 snRNP/U2AF65 communica- 1430--1443 mRNA stabilization by 5'-stem-loop tion {Hoffman and Grabowski), Fungal spore development, interacting structure (Emory et al.), 2554-2568 role of light and circadian clock 135-148 Exonucleases, 5'-3' and 3'-5' (Ctyman (Betl-Pedersen et al.), 2382-2394 N4 early transcription, single-stranded and Belfort), 1269-1279 FUS3 kinase, phosphorylation of, S. cere- DNA-binding protein (SSB) re- External sensory (es) organs, Drosophila, visiae (Gartner et al.}, 1280- quired for (Markiewicz et al.), subtype determination (Higash- 1292 2010-2019 ijima et al.), 1005-1018 fushi tarazu (ftz) homeo domain, Droso- protein export, role of heat shock pro- Extinction, of a~-antitrypsin gene ex- phila, helix-turn-helix motif teins DnaK and DnaJ {Wild et pression (Bulla et al.), 316-327 {Furukubo-Tokunago et al.), al.), 1165-1172 Extracellular matrix protein, normal de- 1082-1096 RecA protein, mediates stable DNA velopment of TN-deficient synapsis (Adzuma), 1679-1694 mice (Saga et al.), 1821-1831 S10 operon, regulation by ribosomal extramacrochaetae (emc) Drosophila G gene, role in controlling spatial protein L4 {Zengel and Lindahl), G protein 2655-2662 pattern of ac and sc transcrip- tion (Van Doren et al.), 2592- Dictyostelium, Ga4 subunit analysis of translational frameshifting, dnaX gene (Hadwiger and Firtel), 38--49 (Tsuchihashi and Brown), 511- 2605 Eye development, Drosophila, dual Bar S. pombe, gpa2 gene encodes Ga sub- 519 unit involved in nutrional mon- ets homeo box genes (Higashijima et al.), 50-60 itoring (Isshiki et al.), 2455- family members, different trans-acting 2462 properties of {Wasylyk et al.), G-G base pair recognition, avian telom- 965-974 F eres {Gualberto et al.), 815-824 oncogene family, new member PEA3 Fibroblast growth factor (FGF) receptor, GABa, target site selection by (Brown (Xin et al.), 481-496 Drosophila, analysis of ho- and McKnight}, 2502-2512 -related proteins, two newly defined molog (breathless)(Kl~imbt et GAGA factor, role in RNA polymerase proteins (ER81 and ER71) al.), 1667-1678 pausing in heat shock gene (Lee (Brown and McKnight), 2502- Fibrosarcoma development, functional et al.), 284-295 2512 role of transcription factors GAL4-VP16 mediated antirepression, of ets-1 proto-oncogene, eukaryotic tran- JunB and c-Jun (Bossy-Wetzel et histone HI-mediated repression scriptional regulator (Nye et al./, 2340-2351 (Croston et al.), 2270-2281 al.}, 975-990 Fission yeast checkpoint genes, coupling GALII, as possible HAP1 cofactor {Tur- Ets of mitosis to completion of cotte and Guarente), 2001-2009 -binding site, of oncogene-responsive DNA replication (Enoch et al.), GATA-1, promoter-enhancer interac- element (Bruder et al.), 545-556 2035--2046 tions regulated by (Fong et al.), transcription activation by (Wasylyk 5' splice site, site-specific cross-linking 521-532 et al.), 965-974 of mammalian U5 snRNP to Gene ETS (Wyatt et al.), 2542-2553 scrambling, O. nova (Mitcham et al.), domain, specificity of DNA binding Flagelllum biosynthesis, Caulobacter, 788-800 (Nye et al.), 975-990 role of r factor (Brun and Sha- targeting, partial loss-of-function mu- family, DNA-binding and protein-pro- piro), 2395-2408 tations (Moens et al.), 691-704 tein interaction specificity fork head domain trap vector, mouse embryonic stem (Brown and McKnight), 2502- Drosophila, novel putative DNA-bind- cells (Skarnes et al.), 903-918 2512 ing domain (Grossniklaus et Genome reorganization, Paramecium, even-skipped (eve} al.), 1030-1051 polyploid macronucleus from pair-rule gene, Drosophila, Eve func- Xenopus, blastopore lip-specific gene diploid nucleus (Meyerl, tions as concentration depen- (Dirksen et al.), 599-608 211-222

2676 GENES & DEVELOPMENT Genomic imprinting hedgehog Drosophila gene, target of en HIV- 1 embryonic development {Rappolee et regulation {Tabata et al.), 2635- promoter, transcription regulation by al.), 939-952 2645 NF-KB {Kretzschmar et al.), preimpantation mouse embryos (Carl- Helix-loop-helix (HLH) 761-774 son et al.), 2536-2541 -bZIP, chimeric transcription factor VP 16 and Tat have functionally inter- Germ cell development, role of SLF (Hunger et al.}, 1608-1620 changeable activation domains (Brannan et al.), 1832-1842 -ZIP domain, Max:c-Myc heteromeric (Tiley et al.), 2077-2087 Globin gene switching, promoter compe- complex (Kato et al.), 81-92 HMG box protein, hUBF (Jantzen et al.), tition (Foley and Engel}, motif, Drosophila ftz homeo domain 1950-1963 730-744 (Furukubo-Tokunago et al.), HO endonuclease gene, yeast, regulated Glucocorticoid response element, inter- 1082-1096 by SW15 (Dohrmann et al.), 93- action with AP-1 (Miner and protein 104 Yamamoto), 2491-2501 Drosophila emc {Van Doren et al.), Holliday junction, E. coli protein com- Granulocyte monocyte colony stimulat- 2592-2605 plex RuvA-RuvB interaction, ing factor (GM-CSF) AU com- encoded by Drosophila dpn gene promotes branch migration plex, and mRNA instability (Sa- (Bier et al.), 2137-2151 {Iwasaki et al.), 2214-2220 vant-Bhonsale and Cleveland), Id associates with E2A proteins (Jen Homeo box 1927-1939 et al.), 1466--1479 -containing genes {HOX), promoter ac- Group I intron, activation of catalytic and insulin (German et al.}, 2165- tivation in transgenic zebrafish core (Michel et al.), 1373-1385 2176 {Westerfield et al.), 591-590 Group I introns, splicing of and similar- muscle-specific, myogenin and gene, Xlim-1 in X. laevis LIM domain ity to tRNAs (Guo and Lam- MyoD {Li et al.), 676-689 {Taira et al.}, 356-366 bowitz), 1357-1372 rat HEAS-1 and HES-3, structural genes, Drosophila Bar region and eye Growth suppression domain, within RB homology to Drosophila hairy development (Higashijima et gene product (Qin et al.), 953- and Enhancer of split (Sasai et al.}, 50-60 964 al.), 2620-2634 Homeo domain Gl-specific genes, dependency on Cdc28 regulatory gene, maize B gene {Radi- ftz Drosophila, helix-turn-helix motif kinase activation {Marini and celia et al.), 2152-2164 (Furukubo-Tokunago et al.), Reed), 557-567 zipper protein, Max, association with 1082-1096 GTP-binding domain, dynamin D100 Myc family proteins (Black- motifs, Coprinus, A mating type gene (Jones and Fangman), 380-389 wood et al.), 71-80 complexes (Kiies et al.), G 1 regulation, of S. cerevisiae, role of Hematopoiesis {Holmgren and Engel), 568-577 SIT4 gene (Femandez-Sarabia et 161-165 (meeting review) proteins al.), 2417-2428 Heme transport, and bacterial cy- Drosophila activator UBX and re- tochrome c biogenesis (Beck- pressor EVE {Johnson and Kras- man et al.), 268-283 now), 2177-2189 H Hemopoietic differentiation, role of Oct-1 POU, recognition of surface RARa transcription factor (Tsai {Pomerantz et al.), 2047-2057 hairless {H) Drosophila gene, protein et al.), 2258-2269 Homeo domains, Dfd and Ubx, mapping controls SOP cell fate (Bang and Hepatic development, albumin gene ac- Posakony), 1752-1769 functional specificity {Lin and tivators {Milos and Zaret), 991- McGinnis), 1071-1081 Hairy (h) 1004 Homeobox genes, redundant, Drosophila Drosophila, rat HLH proteins HES-1 Heptapeptide repeats, of RNAP II CTD, BarH1 and BatH2 (Higashijima and HES-3 are structurally re- phosphorylation of (Peterson et et al.), 1005-1018 lated to {Sasai et al.), 2620-2634 al.}, 426-438 Homeotic gene product, Drosophila, pan-neural Herpes simplex virus gene {dpn) closely related to Oct-1 multiprotein complex {C1) (Po- complex HOM-C, Drosophila, map- (Bier et al.), 2137-2151 merantz et al.), 2047-2057 ping functional specifity in Dfd Half-life, of c-myc mRNA {Bemstein et trans-activator VP16, association with and Ubx (Lin and McGinnis), al.), 642-654 POU protein Oct-1 and Oct-2 1071-1081 HAP1 activator, yeast, cofactor interac- (Lai et al.), 2058-2065 Drosophila gene, Antp, intemal ribo- tion (Turcotte and Guarente), HES family, HLH factors, structurally re- some binding of mRNA (OH et 2001-2009 lated to Drosophila h and E(spl) al.), 1643-1653 Heat shock (Sasai et al.), 2620-2634 genes genes Heteromeric complex, Max:c-Myc (Kato Drosophila repression by Polycomb Drosophila, DNA melting of (Giar- et al.), 81-92 group {PcG) (DeCamillis et al.), dina et a1.),2190-2200 Hexagonal actin-myosin network, Dro- 223-232 RNA polymerase pausing on hsp70 sophila hullo gene stabilizes Drosophila Ubx promoter activation (Lee et al.), 284-295 (Rose and Wiecschaus), 1255- {Laney and Biggin), 1531-1541 proteins, DnaK and DnaJ, role in E. 1268 Homologous recombination coli protein export (Wild et al.), Histone branch migration in (Iwasaki et al.), 1165-1172 Hi-mediated repression, counteracted 2214-2220 response, and splicing pathway (Utans by GAL4--VP 16 hybrid activator mto human 13-globin LCR (Kim et al.), et al.), 631-641 (Croston et al.), 2270-2281 919-927 hsp70/HSF interaction (Abravaya et H4, and nucleosome positioning (Roth role of recA protein during DNA syn- al.), 1153-1164 et al.), 411--425 apsis {Adzuma}, 1679-1694

GENES & DEVELOPMENT 2677 HPV production, in epithelial raft cul- P7, novel antisense system motifs in (Green and Mathews), tures (Dollard et al.), 1131-1142 (Biere et al.), 2409-2416 2478-2490 HSF, interaction with hsp70 (Abravaya Immortalization, of chicken cells, as dis- Kinases, S. cerevisiae et al.), 1153-1164 tinct from cell transformation FUS3, STEll, and STE7 (Gartner et hSL1, TBP-TAF complex, interaction (Ulrich et al.), 876-887 al.), 1280-1292 with hUBF activation domain In vitro selection, of hairpin ribozymes STE7 and STE11 (Cairns et al.), 1305- (Jantzen et al.), 1950-1963 (Berzal-Herranz et al.l, 129-134 1318 Hsp70, Drosophila, consequences of ex- Influenza virus, nucleocytoplasmic KMnO4, as probe for single-stranded pression at normal temperature transport of mRNA (Alonso-Ca- DNA (Giardina et al.), 2190-- (Feder et al.), 1402-1413 plen et al.), 255-267 2200, {Krumm et al.), 2201- HSV- 1 regulatory protein, ICP27, affects Insulin I rat gene, minienhancer com- 2213 mRNA processing (Sandri-Gol- plex (German et al.), 2165-2176 din and Mendoza), 848-863 Insulin receptors, preimplantation HTLV-1, Tax1 transcriptional activator mouse embryos (Rappolee et L and transforming protein (Fujii al.), 939-952 LacZ et al.), 2066-2076 Insulin-like growth factor gene expression, TN-deficient mice, hu-li-tai shao (hts), Drosophila gene, en- IGF-II/IGF-I receptor pathway in lacZ replaces TN (Saga et al.), codes adducin homolog {Yue mouse embryos {Rappolee et 1821-1831 and Spradling), 2443-2454 al.), 939-952 reporter, mouse ES cells, and gene trap hUBF activation domains, cooperative II (Igf2), mouse, parental imprinting vector (Skames et al.), 903-918 interactions with TBF-TAF (Sasaki et al.), 1843-1856 LAP, transcription factor, CHOP inhib- complex hSL1 (Jantzen et al.), Integration sites, of Ty3 retrovirus-like its function (Ron and Habener), 1950-1963 element (Chalker and Sandm- 439-453 Human eyer), 117-128 Leukemogenesis, chromosomal translo- hsp70 protein, interaction with HSF Interleukin-7 (IL-7), N-rnyc and C-myc cations, oncogenic conversion {Abravaya et al.), 1153-1164 regulation in pre-B lymphocytes by transcription factors (Hunger papillomavirus. See HPV. (Morrow et al.), 61-70 et al.), 1608-1620 salivary amylase gene (AMY1C}, tis- Internal eliminated sequences, O. nova, LIM sue-specific expression, retrovi- removal of (Mitcham et al.), domain, Xenopus laevis homeo box ral sequences required for (Ting 788-800 gene Xlim-1 (Taira et al.), 356- et al.I, 1457-1465 Intron 366 splicing factor ASF/SF2, Drosophila core, binding by tyrosyl-tRNA synthe- gene family, Drosophila, ap gene (Co- RNA binding protein RBP1 tase (Guo and Lambowitz), hen et al.}, 715--729 shows functional similarity to 1357-1372 -homeo domain protein, and insulin (Kim et al.), 2569-2578 mobility, trans and cis requirements minienhancer complex (Ger- Human/Mel hybrid, human B-globin (Clyman and Belfort), 1269- man et al.I, 2165-2176 LCR (Kim et al.), 928-938 1279 Limb development, chicken ld gene Hybrid cells (hepatoma/fibroblast), ex- (Trumpp et al.), 14-28 tinction of liver specific oq-AT Locus control region (LCR), human gene (Bulla et al.), 316-327 f~-globin gene, homologous re- Hydrophobin Jun combination into (Kim et al.), encoded by N. crassa ccg-2 gene (Bell- family of oncogenes, fibrosarcoma de- 919-927 Pedersen et al.), 2382-2394 velopment (Bossy-Wetzel et al.), Lung branching morphogenesis, mouse, gene family, N. crassa eas gene is 2340-2351 role for N-myc {Moens et al.), member of (Lauter et al.), 2373- and muscle transcription, repression 691-704 2381 of (Li et al.), 676-689 oncoprotein, HOB motifs of (Suther- land et al.), 1810-1819 I M see also oncoproteins ICP27, HSV-1 regulatory protein, post- Macronuclear transcriptional effect on mRNA destined sequences (MDS), O. nova, K processing (Sandri-Goldin and reordering and splicing Mendoza), 848-863 Karyogamy, yeast, genes involved in (Mitcham et al.), 788-800 Id HLH protein, associates with E2A pro- (Page and Snyder), 1414--1429 development, Paramecium primaure- tein, inhibition of muscle differ- Keratinocyte, differentiation {Dollard et lia, telomere addition sites entiation (Jen et al.), 1466-1479 al.), 1131-1142 (Meyer), 211-222 IKB protein family, bcl-3 and IKB~ are Keratinocytes, TNF~ production (Cheng MADS gene family, MEF2 factors are members of (Kerr et al.), 2352- et al.), 1444-1456 members of (Yu et al.), 1783- 2363 Kidney development, chicken ld gene 1798 Imaginal disc development, Drosophila, (Trumpp et al.}, 14-28 Maize apterous (ap) gene (Cohen et Kinase anthocyanin pigmentation pathway al.), 715-729 cascade, role in pheromone response (Goff et al.), 864-875 Immediate early genes, HTLV-1, aber- pathway (Stevenson et al.), B regulatory gene, allelic diversity of rant induction of (Fujii et al.}, 1293-1304 (Radicella et al.}, 2152-2164 2066--2076 double-stranded RNA-activated pro- seed maturation, VP 1 activation of the immI region of bacteriophages P1 and tein kinase (DAI), RNA-binding C1 gene (Hattori et al.), 609-618

2678 GENES & DEVELOPMENT Male sterility, resulting from activated Microtubule processing int-3 transgenic mice (Jhappen -binding protein, dynamin D100 (Jones affected by HSV-1 regulator (San&i- et al.), 345-355 and Fangman), 380--389 Goldin and Mendoza), 848-863 Mammary glands, lactation deficiency, function, S. cerevisiae gene involved defects of in prp20 yeast mutation resulting from activated int-3 in (Page and Snyder), 1414-1429 {Forrester et al.), 1914-1926 locus (Jhappen et al.), 345-355 Midblastula transition, X. laevis, tran- stability Masked mRNA, X. laevis, activation of scription activation (Lund and c-myc [Bemstein et al.), 642-654 by cytoplasmic poly(A) elonga- Dahlberg), 1097-1106 E. coli, 5'-stem-loop structure (Em- tion (Simon et al.), 2580-2591 Minienhancer complex, components of ory et al.I, 135-148 Maternal (German et al.), 2165-2176 nucleocytoplasmic transport, influ- effect genes, Drosophila pumilio and Mitochondrial enza virus (Alonso-Caplen et nanos (Barker et al.), 2312-2326 DNA (mtDNA), nuclear genes re- al.), 255-267 morphogen, Drosophila dorsal (dl) (Ip quired for maintenance (Jones MuA tetramer, DNA promoted assem- et al.), 1728-1739 and Fangman), 380-389 bly of (Baker and Mizuuchi}, mRNAs, murine, regulated by cyto- RNA processing, tyrosyl-tRNA syn- 2221-2232 plasmic polyadenylation {Sall6s thetase (Guo and Lambowitz}, Murine mammary tumor virus. See et al.), 1202-1212 1357-1372 MMTV Mating type, Coprinus A gene com- RNA, RNase MRP (Schmitt and Clay- Muscle differentiation, inhibition of, Id plexes (Ktiues et al.), 568-577 ton), 1975-1985 association with E proteins Max Mitosis (E2A) (Jen et al.), 1466--1479 homodimer, DNA-binding activity in- coupled to completion of DNA repli- Muscle transcription, repression of by hibited by CKII (Berberich and cation, role of fission yeast Fos and Jun (Li et al.), 676-689 Cole), 166-176 genes (Enoch et al.), 2035-2046 Muscle-specific gene regulation, MEF2 protein yeast, role of cyclin-B homologs {Clb factors are members of MADS biphasic effect of on Myc cotransfor- proteins) (Richardson et al.), family (Yu et al.), 1783-1798 mation activity (Prendergast et 2021-2034 Mutagenic strategies, vertebrate {Ros- al.), 2429-2439 Mitotic control, mammalian cells, sant and Hopkins), 1-13 (Re- functional domains of and interac- mouse cdc25 homolog (Kaki- view) tion with c-Myc (Kato et al.), zuka et al.), 578-590 Mutant p53 protein, inhibits wild-type 81-92 MMTV, integration into int-3 locus acti- p53 binding {Bargonetti et al.), helix-loop--helix zipper protein, asso- vated Notch-related flanking se- 1886-1898 ciation with Myc family pro- quences {Jhappen et al.), myc gene teins (Blackwood et al.), 71-80 345-355 expression, IL-7 regulated {Morrow et interaction with Myc proteins Mouse al. ), 61-70 (Mukherjee et al.), 1480-1492 cdc25 homolog, developmental ex- family, regulatory interaction between MCK (muscle creatine kinase)gene, pression (Kakizuka et al.), 578- identification of wild-type p53 c-myc and N-myc {Stanton et 590 al.l, 2235-2247 responsive element {Zambetti embryogenesis et al.), 1143-1152 Myc function of N-myc during (Stanton McpA chemoreceptor, C. crescentus, po- cotransformation, biphasic effect of lar localization of (Alley et al.}, et al.), 2235-2247, (Charron et Max on (Prendergast et al.I, 825-836 al.), 2248-2257 2429-2439 Methylation regulatory role of PEA3 (Xin et al.], family proteins, common transforma- gene-specific, mouse development 481--496 tion pathways including Max (Kafri et al.), 705-714 embryos, endogenous growth pathway interaction (Mukherjee et al.), patterns, preimplantation mouse em- (Rappolee et al.), 939-952 1480-1492 bryos (Carlson et al.), 2536- limb deformity {ld) locus, alternatively Myc:Max, sequence-specific DNA-bind- 2541 spliced transcripts of (Jackson- ing complex (Blackwood et al.), MF3 protein, specificity for single Grusby et al.), 29-37 71-80 stranded telomere probes (Gual- insulin-like growth factor (Igf2) gene, Myc/Max heterodimers, DNA-binding berto et al.), 815-824 parental imprinting (Sasaki et activity, unaffected by CKII MFA2 yeast gene al.), 1843-1856 {Berberich and Cole), 166-176 decay and deadenylation of mRNA mRNA Myocyte-specific enhancer factors 2 (Muhlard and Parker), 2100- degradation (MEF2), members of MADS box 2111 specificity of RNase E (Ehretsmann family (Yu et al.), 1783--1798 3'-UTR-dependent deadenylation of et al.), 149-159 MyoD, muscle-specific HLH protein (Li RNA (Lowell et al.), 2088-2099 yeast, deadenylation of MFA2 tran- et al.), 676-689 MGM1, S. cerevisiae, mitochondrial ge- script (Muhlard and Parker), Myogenic differentiation, inhibition of nome maintenance gene (Jones 2100-2111 by adenovirus Ela protein and Fangman), 380-389 export, Saccharomyces cerevisiae, (Braun et al.), 888-902 Mice RAT1 gene (Amberg et al.), Myogenin, muscle-specific HLH protein normal development of TN-deficient 1173-1189 (Li et al.), 676--689 mice (Saga et al.), 1821-1831 instability, and GM-CSF AU complex Myxococcus xanthus, csgA expression splicing defect in Steel ~zH {Brannan et (Savant-Bhonsale and Cleve- entrains development {Li et al.), al.), 1832-1842 land), 1927-1939 401--410

GENES & DEVELOPMENT 2679 N nuclear export of RNA (Alonso- (Steinhauer and Kalfayan), 233- Caplen et al.), 255--267 243 N-myc Nuclear Ovarian development, Drosophila pro- gene hormone receptors, RARs and RXRs tein expression from otu (Stein- function of during mouse embryo- (Mangelsdorf et al.}, 329-344 hauer and Kalfayan), 233-243 genesis and regulatory interac- import, U3 snRNA, molecular signals Oxidative stress, E. coli, Dps protects tion with c-myc (Stanton et al.), for (Baserga et al.), 1120-1130 DNA (Almir6n et al.), 2646- 2235-2247 localization, of Max protein (Prender- 2654 physiological function distinct from gast et al.), 2429-2439 Oxytricha nova, e~-telomere-binding pro- other myc genes (Charron et localization sequences (NLS], of tein, (Mitcham et al.), 788-800 al.), 2248-2257 NF-KB, interaction with IKB role in mouse lung development (Beg et al.), 1899-1913 (Moens et al.), 691-704 protein, CHOP, dominant-negative in- see also myc gene hibitor of transcription {Ron P-element splicing, Drosophila, mecha- N4. See also coliphage N4 and Hbener), 439-453 nism regulating (Siebel et al.), Negative regulation, by c-Myb carboxy- transport, Drosophila, dorsal protein 1386--1401 terminal element (Dubendorff {Norris and Manley), 1654-1667 p50 subunit, of NF-KB (Kretzschmar et et al.), 2524-2535 Nucleocytoplasmic transport, influenza al.), 761-774 Nervous system, regulation of Hox ex- virus mRNA (Alonso-Caplen et transcription factor (Fujita et al.), 775- pression (Westerfield et al.), al.), 255-267 787 591-598 Nucleosome positioning, by a2 repressor p53 Neural and histone H4 (Roth et al.), gene product, naturally occuring wild- precursor cells, Drosophila (Bier et al.), 411-425 type DNA-binding element 2137-2151 Nucleosomes (Zambetti et al.), 1143-1152 tube, dorsoventral polarity and inhibit transcription initiation (Lorch loss of during cell immortalization chicken ld gene products et al.), 2282-2287 (Ulrich et al.), 876-887 (Trumpp et al.), 14-28 yeast, as opposed to telosomes (Wright protein, site-specific binding of (Bar- Neurogenesis (Holmgren and Engel), et al.), 187-210 gonetti et al.), 1886-1898 161-165 (meeting review) Nullo gene, Drosophila cellularization p65 subunit, of NF-KB transcription fac- Drosophila, role of spitz gene (Rut- {Rose and Wiecschaus), 1255- tor (Fujita et al.), 775-787 ledge et al.}, 1503-1507 1268 p67 sRr GaArG-binding factor, interac- Neurogenic genes, Drosophila SOP cell NusA transcription factor, E. coli S 10 op- tion with HTLV-1 Taxl, aber- fate, interaction with Hairless eron, required to promote RNA rant induction of cell growth (H) gene (Bang and Posakony), polymerase pausing at termina- (Fujii et al.), 2066-2076 1752-1769 tion site (Zengel and Lindahl), Pair-rule gene, Drosophila Neurospora crassa 2655-2662 even-skipped {eve), Eve functions as concentration-dependent mor- bli-7 gene is structural eas gene, en- O codes major rodlet protein (Lau- phogen [Manoukian and ter et al.), 2373-2381 Oct-1 Krause}, 1740-1751 clock-controlled gene ccg-2 allelic to homeo domain, VP 16 association, role ftz (Furukubo-Tokunago et al.), 1082- eas gene (Bell-Pedersen et al.), of Glu-22 (Lai et al.), 2058-2065 1096 and proneural gene expression (Skeath 2382-2394 POU domain, HSV, recognition of sur- et al.), 2606-2619 sporulation pathways, con gene ex- face (Pomerantz et al.), 2047- Pair-rule pression (Springer and Yanof- 2057 locus, Drosophila, slp (Grossniklaus et sky), 1052-1057 Oct-2 homeo domain, Glu-22 substitu- tion confers VP16 associations al.), 1030-1051 NF-KB transcription factor {Lai et al.), 2058-2065 segmentation gene, Drosophila hairy I-Rel inhibits activity {Ruben et al.), Ommatidia development. See Eye devel- {h) (Sasai et al.), 2620-2634 730-744 opment Paired domain transcription factor, pS0 and p65 subunits, independent ompA transcript, E. coli, 5'-untranslated BSAP encoded by Pax-5 gene modes of activation (Fujita et region acts as stabilizer (Emory (Adams et al.), 1589-1607 al.), 775-787 et al.), 135-148 Pan-neural genes, Drosophila deadpan pS0 subunit {Kretzschmar et al.), 761- Oncogene, myb (Dubendorff et al.), (dpn) encodes HLH protein (Bier 774 2524--2535 et al.), 2137-2151 NF-KB, NLS/IKB interaction (Beg et al.), Oncogenesis (Holmgren and Engel), 161- Papillomavirus, E2 protein, dimerization 1899-1913 165 {meeting review) and DNA binding {Prakash et Non-AUG initiation, translational acti- Oncogenic conversion, of bZIP protein al.), 105-116 vataion of c-myc (Hann et al.), Hlf {Hunger et al.), 1608-1620 Paramecium prirnaurelia, induction of de- 1229-1240 Oncoproteins velopmental mutations (Meyer), Nonessential genes, Drosophila zeste ac- Fos and Jun, activation domain 211-222 tivates Ubx transcription (Sutherland et al.), 1810-1819 Parental imprinting, mouse insulin-like (Laney and Biggin), 1531-1541 Jun and Fos {Oliviero et al.), 1799- growth factor II (Igf2) (Sasaki et Nonsense mutations, MVM RNA, inhi- 1809 al.), 1843-1856 bition of splicing (Naeger et al.), Myc family (Mukherjee et al.), 1480- Parotid-specific expression, human sali- 1107-1119 1492 vary amylase gene AMY1C NS1 protein, influenza virus regulates Oogenesis, Drosophila, role of otu (Ting et al.), 1457-1465

2680 GENES & DEVELOPMENT Parvovirus minute virus of mice (MVM), tail Preinitiation complex (prelC), Droso- nonsense mutations inhibit length, regulates polyadenylation phila, differential regulation of splicing (Naeger et al.), 1107- {Gershon and Moss), 1575-1586 by UBX and EVE (Johnson and 1119 yeast, shortening of by PAN is 3'- Krasnow}, 2177-2189 Pattern formation UTR dependent {Lowell et al.), Prepattem, in Drosophila developing eye A. nidulans, stuA gene required 2088-2099 (Dickson et al.), 2327-2339 {Miller et al.), 1770-1782 Polyadenylation Prespliceosomes, protein components of Drosophila regulated by poly(A) tail length (Ger- (Bennet et al.), 1986-2000 slp genes (Grossniklaus et al.), 1030- shon and Moss), 1575-1586 Prions, replication of in transgenic mice 1051 X. laevis embryogenesis, identifica- and hamsters (Hecker et al.), wing imaginal disc (Van Doren et tion of novel cytoplasmic cis- 1213--1228 al.), 2592-2605 acting element {Simon et al.), Processivity factor, in vitro, HIV-1 Tat vertebrate, mouse limb development 2580-2591 (Kato et al.), 655-666 (lackson-Grusby et al.), 29-37 Polycomb chromo domain, Drosophila, Promoter X. laevis gastrula embryos, role of reequired for chromatin binding -binding factors, counteract chroma- X//rn-I gene (Taira et al.), 356- (Messmer et al.), 1241-1254 tin-mediated repression (Cros- 366 Polycomb group (PEG) genes, Droso- ton et al.), 2270--2281 Pax-5 gene, encodes paired domain tran- phila, ph and Pc interaction competition, globin gene switching scription factor BSAP {Adams et (DeCamillis et al.), 223-232 {Foley and Engel), 730-744 al.), 1589-1607 polyhorneotic gene (ph), Drosophila, en- melting, on Drosophila genes in vivo PEA3, Ets oncogene family, regulatory codes chromatin protein (De- (Giardina et al.), 2190-2200 role during mouse embryogene- Camillis et al.), 223-232 trap vectors, ES cells, gene disruption sis (Xin et al.), 481-496 Polymerase II transcription, stimulated (yon Melchner et al.), 919-927 Peripheral nervous system development, by acidic activator GAL4-AH Promoter-enhancer Drosophila, couch potato (cpo) and TFIIA and IID (Wang et al.), interaction, 13-globin gene, regulation gene (Bellen et al.), 2125-2136 1716-1727 by GATA-1 (Fong et al.), 521- Phage T4, td intron (Clyman and Bel- Polyomavirus enhancer, oncogene-re- 532 fort), 1269-1279 sponsive element (Bruder et al.), competition, LCR function and globin Pheromone 545-556 gene switching (Kim et al.), response pathway, S. cerevisiae Positive control mutants, of yeast HAP1 928-938 components order of action (Cairns activator (Turcotte and Gua- Promoters, RNA polymerase II, TFIID et al.), 1305-1318 rente}, 2001-2009 interaction (Colgan and Man- kinase cascade {Stevenson et al.), Post-transcriptional regulation, HSV-1 ley), 304-315 1293-1304 regulatory protein ICP27 (San- Proneural gene expression, Drosophila signal transduction pathway, S. cerevi- dri-Goldin and Mendoza), 848- {Skeath et al.), 2606-2619 863 siae (Gartner et al.), 1280-1292 Protein POU domain, of Oct-1 (Pomerantz et al.), Phosphorylation export, E. co//, role of heat shock pro- 2047-2057 of FUS3 kinase, S. cerevisiae (Gartner teins DnaK and DnaJ {Wild et and Oct-1 (Lai et al.), 2058-2065 et al.), 1280-1292 al.), 1165-1172 pqp gene, Drosophila zinc finger protein, of Max homodimers (Berberich and kinase, DNA dependent, signal for oocyte nucleus localization Cole), 166-176 phosphorylation (Peterson et (S6galat et al.), 1019-1029 and RB gene product (Qin et al.), 953- al.), 426--438 964 Pre-mRNA splicing shutdown resulting from heat shock kinase A (PKA), down-regulation by of RNAP II CTD heptapeptide repeats (Utans et al.), 631-641 v-Ras and PKC (Gallo et al.), (Peterson et al.), 426--438 site-specific cross-linking prior to 1621-1630 yeast signal transduction, of STE7 ki- {Wyatt et al.), 2542-2553 kinase C (PKC), down-regulates nu- nase (Cairns et al.), 1305-1318 SR proteins, conserved family (Zahler clear PKA (Gallo et al.), 1621- Photoreceptor, phytochrome A (phyA) et al.}, 837-847 1630 (Stockhaus et al.), 2364-2372 U6 snRNA as catalytic element in phosphatase SIT4, S. cerevisiae late Phytochrome A (phyA), structure/func- spliceosome (Sawa and Shi- G~, required for normal accu- tion relationship, serine-to-ala- mura), 244-254 mulation of SWI4 (Fernandez- nine substitutions {Stockhaus Pre-mRNAs, processing of, role of Sarabia et al.), 2417-2428 et al.), 2364-2372 Drosophila rpbl gene (Kim et sequestration, Drosophila hsp70 Pigment cell formation, Drosophila, al.), 2569-2578 {Feder et al.), 1402-1413 dual Bar homeo box genes (Hi- Precursor B lymphocytes, IL-7-regulated Protein-DNA gashijima et al.), 50--60 myc gene expression {Morrow complexes, tetramer of Mu trans- PNS. See Peripheral nervous system et al.), 61-70 posase {MuA) {Baker and Mi- Polarity, bacterial chemoreceptor {Alley Preimplantation mouse zuuchi), 2221-2232 et al.), 825-836 development interactions, insulin minienhancer Poly(A) gene expression during {Rothstein et complex (German et al.), 2165- elongation, X. laevis development, al.), 1190-1201 2176 translational control by {Simon imprinted genes influence develop- Protein-protein interaction et al.), 2580-2591 ment (Rappolee et al.), 939-952 at composite response elements nuclease {PAN), yeast tail degradation embryos, localization of DNA MTase {Miner and Yamamoto), 2491- {Lowell et al.}, 2088-2099 {Carlson et al.), 2536--2541 2501

GENES & DEVELOPMENT 2681 and maize anthocyanin pigmentation Rel RNA pathway (Goff et al.), 864-875 protein -binding recognition of surface of Oct-1 POU family, I-Rel inhibits NF-KB tran- factor, Drosophila RMP1, functional homeo domain {Pomerantz et scriptional activity (Ruben et similarity to human splicing al.), 2047-2057 al.), 745-760 factor ASf/SF2 (Kim et al.), TBF-TAF complex hSL1 (Jantzen et DNA-binding activity of (Kerr et al.), 2569-2578 al.), 1950-1963 2352-2363 motifs, in DAI (Green and VP16 association with Oct-1 vs Oct-1 transcription factors, Drosophila dl Mathews), 2478-2490 (Lai et al.), 2058-2065 morphogen (Isoda et al.), protein, Drosophila cpo shows ho- Proto-oncogene 619-630 mology to (Bellen et al.}, 2125- N-myc, mouse lung development Repressor/activator protein 1 {RAP1), 2136 (Moens et al.), 691-704 yeast, activity at silencers and cleavage reaction, hairpin ribozyme Raf-1, activation by serum, TPA and telomeres (Hardy et al.), {Berzal-Herranz et al.), 129-134 Ras (Bruder et al.), 545-556 801-814 Pol I factor hUBF, activation domains see also individual genes Retinoblastoma of {Jantzen et al.), 1950-1963 Proto-oncogenes gene (Rb), expression of during immor- polymerase, of N4 DNA virus (Mark- junB and c-jun, fibrosarcoma develop- talization (Ulrich et al.), iewicz et al.), 2010-2019 ment (Bossy-Wetzel et al.), 876-887 polymerase II 2340-2351 susceptibility gene Drosophila, analysis of dTFIIB (Wampler and Kadonaga}, 1542- see also individual genes RB, growth suppression domain 1552 prp20 yeast mutants, defects in mRNA within (Qin et al.), 953-964 RB1, E2F-pRB interaction (Hiebert elongation of [Kato et al.), 655--666 processing (Forrester et al.), heptapeptide repeats, phosphoryla- 1914-1926 et al.), 177-185 Retinoic acid receptor tion of (Peterson et al.), 426-438 rAR systems as compared to RXR fam- holo-THID complex {Zhou et al.), ily (Mangelsdorf et al.), 329-344 1964-1974 R transcription factor (RARa), role in he- promoters, TATA-TFIID interac- R7 cell development, Drosophila {Dick- mopoietic differentiation (Tsai tions {Colgan and Manley), 304- son et al.), 2327-2339 et al.), 2258-2269 315 Raf-1, activation by serum, TPA and Ras Retrotransposition, and evolution of SII-dependent transcript truncation {Bruder et al.}, 545-556 gene regulation (Ting et al.), (Izban and Luse), 1342-1356 Raft culture, production of HPV (Dollard 1457-1465 transcription initiation on chroma- et al.), 1131-1142 Retrotransposon Ty3, preferential inser- tin templates {Lorch et al.}, 2282-2287 RAPl-interacting factor (RIF1), mediator tion of {Chalker and Sandm- transcription termination (Roberts for RAP1 (Hardy et al.), 801-814 eyer), 117-128 Retroviral sequences, required for tissue- et al.), 1562-1574 Ras specific expression, human sali- transcriptional antirepression by cotransformation assays, biphasic ef- vary amylase gene (Ting et al.), GAL4-VP16 (Croston et al.), fect of Max on Myc {Prendergast 1457-1465 2270-2281 et al.I, 2429-2439 Retrovirus, promoter trap vectors polymerase III signaling pathway, and eIF-4E-induced (U3His and U3Neo) (yon Melch- transcription, and TH1B-related fac- transformation (Lazaris-Karat- ner et al.), 919-927 tor BRF1 (Colbert and Hahn), zas et al.), 1631-1642 Rev protein of HIV-1, RNA-binding do- 1940-1949 Rat main of (Tiley et al.), 2077-2087 Ty3 integrates within transcription HLH proteins HES-1 and HES-3, struc- Rex system, bacteriophage lambda, cell initiation region (Chalker and tural homology to Drosophila death (Parma et al.), 497-510 Sandmeyer), 117-128 hairy and Enhancer of split (Sa- rho-dependent termination, and c4 RNA polymerase pausing sai et al.), 2620-2634 controlled expression of the ant Drosophila genes, promoter melting insulin I gene, minienhancer complex gene {Biere et al.), 2409-2416 (Giardina et al.),2190-2200 (German et al.), 2165-2176 Rhodobacter capsulatus, cytochrome c hsp70, DNA requirements of (Lee et RAT1 yeast gene, mRNA export (Am- biogenesis (Beckman et al.), al.), 284-295 berg et al.), 1173-1189 268-283 promoter-proximal, and block to RBP1, Drosophila RNA-binding protein, Rhomboid (rho} expression, Drosophila transcriptional elongation pre-mRNA processing (Kim et embryo, stripes regulated by dl (Krumm et al.), 2201-2213 al.), 2569-2578 (Ip et al.), 1728-1739 processing RecA protein, E. coli, mediates stable Ribonuclease, PAN and mRNA degrada- RNase E's role in T4 and E. coli synapsis of homolog DNA (Ad- tion (Lowell et al.), 2088-2099 mRNA degradation {Ehrets- zuma), 1679-1694 Ri~bosomal protein L4, E. coli, regulation mann et al.), 149-159 Recombinases, RecA and UvsX (Clyman of S10 operon (Zengel and Lin- RNase MRP RNA, nuclear role of and Belfort), 1269-1279 dahl), 2655-2662 enzyme {Schmitt and Clayton), Recombination pathway, intron mobil- Ribozyme 1975-1985 ity (Clyman and Belfort), 1269- core, group I introns (Michel et al.), -protein interactions, exon-bridging 1279 1373-1385 model (Hoffman and Redundancy, Drosophila, and regulation hairpin, in vitro selection of (Berzal- Grabowski), 2554-2568 of Ubx and other genes (Laney Herranz et al.), 129-134 recognition motif (RRM), isolation and and Biggin), 1531-1541 Ring canals. See Cytoplasmic bridges characterization of rpbl Droso-

2682 GENES & DEVELOPMENT phila gene (Kim et al.), 2569- spindle pole body and microtubule differentiation 2578 function (Page and Snyder), Drosophila transcription factor en- structure, 5'-stem-loop structure sta- 1414-1429 coded by sd (Campbell et al.), bilizes E. coli mRNA (Emory et telomeres, assume non-nucleosomal 367-379 al.), 135-148 chromatin structure (Wright et precursor (SOP) cells, Drosophila PNS trafficking, RatlP/Seplp homology al.), 187-210 H gene controls cell fate (Bang (Amberg et al.), 1173-1189 telomeric and subtelomeric chromatin and Posakony), 1752-1769 -RNA interactions, sunY intron (Wright et al.), 187-210 Seplp, yeast, homology to Ratlp (Am- (Michel et al.), 1373-1385 3' splice site selection (Frank and berg et al.), 1173-1189 RNase MRP RNA, yeast/mammal ho- Guthrie), 2112-2124 Sevenless activity, different response of mology, nuclear role of enzyme transcription, SPT3 interaction with Drosophila ommatidial cells to (Schmitt and Clayton), 1975- TFIID (Eisenmann et al.), 1319- (Dickson et al.), 2327-2339 1985 1331 Sexual development, Coprinus, A-mat- Rodlet transcriptional activators, SNF pro- ing-type gene complexes (Kfies layer, N. crassa, ccg-2 gene encodes teins, GAL4, and Bicoid (Lau- et al.), 568-577 hydrophobin required for (Bell- rent and Carlson), 1707-1715 r C. flagellum biosynthesis (Brun and Pedersen et al.), 2382-2394 translation initiation and UV resis- Shapiro), 2395-2408 protein, N. crassa (Lauter et al.), 2373- tance, role of SSL1 gene product Signal transduction 2381 (Yoon et al.), 2463-2477 pathway rpoN Caulobacter gene, and normal cell Salivary amylase gene human, parotid- Drosophila, nuclear transport of dor- division (Brun and Shapiro), specific expression (Ting et al.), sal protein (Norris and Manley), 2395-2408 1457-1465 1654-1667 rRNA transcription, negative supercoil- Scalloped (sd) gene, Drosophila sensory HTLV-1, Taxi aberrant induction of ing and topoisomerase activity organ differentiation, evolution- cell growth (Fujii et al.), 2066- (Schultz et al.), 1332-1341 arily conserved transcription 2076 RuvA-RuvB protein complex, E. coli, in- factor (Campbell et al.), intracellular, S. pombe, coupling of teraction with Holliday junc- 367-379 mitosis to completion of DNA tion promotes branch migration Schizosaccharomoyces pore be replication (Enoch et al.), 2035- (Iwasaki et al.), 2214--2220 checkpoint genes (Enoch et al.), 2035- 2046 RXR gene family, ligand specificity and 2046 Ras mediates 4E-induced transfor- expression (Mangelsdorf et al.), nutritional monitoring and cAMP pro- mation (Lazaris-Karatzas et al.), 329-344 duction (Isshiki et al.), 2455- 1631-1642 2462 Dictyostelium, G protein ot subunit S Scrapie prions, replication of (Hecker et (Hadwiger and Firtel), 38-49 S phase, S. cerevisiae, role of CLBS-a al.), 1213-1228 Raf- 1 proto-oncogene activation novel B cyclin (Epstein and scute (sc) Drosophila gene (Bruder et al.), 545-556 Cross), 1695-1706 auto-and cross-regulatory activities S. cerevisiae Saccharomyces cerevisiae antagonized by emc gene (Van pheromone response (Cairns et al.), Cdc28-dependent transcriptional acti- Doren et al.), 2592-2605 1305-1318 vation (Marini and Reed), 557- controlled by axis patterning genes phosphorylation of FUS3 kinase 567 (Skeath et al.), 2606-2619 (Gartner et al.), 1280-1292 cyclin-B homologs function in S phase SecB, chaperone, E. coli protein export yeast pheromone response (Stevenson and in G 2 (Richardson et al.), (Wild et al.), 1165-1172 et al.), 1293-1304 2021-2034 Segment polarity gene Single-stranded DNA-binding mitochondrial genome maintenance en, Drosophila, directly activated by activity, MF3 (Gualberto et al.), 815- gene (Jones and Fangman), 380- Eve (Manoukian and Krause), 824 389 1740-1751 protein (SSB), E. coli, required for N4 pheromone response pathway, kinase Drosophila hedgehog {hh), target of en- early transcription (Markiewicz cascade (Stevenson et al.), 1293- grailed (en) regulation (Tabata et al.), 2010-2019 1304 et al.), 2635-2645 Site-specific prp20 mutation, defects in mRNA pro- Segmentation binding, of wild-type p53 protein (Bar- cessing (Forrester et al.), 1914- Drosophila, slp locus (Grossniklaus et gonetti et al.), 1886-1898 1926 al.), 1030-1051 cross-linking, of mammalian U5 sn- RAT1 gene, mRNA export (Amberg et pair-rule gene eve, Eve functions as RNP to 5' splice site (Wyatt et al.), 1173-1189 concentration dependent mor- al.), 2542-2553 RNA levels of G1 cyclins (Fernandez- phogen (Manoukian and snail gene expression, Drosophila meso- Sarabia et al.), 2417-2428 Krause), 1740-1751 derm, dorsal-twist interaction RNase MRP RNA, mammalian ho- Self-splicing, of group I introns (Michel (Ip et al.), 1518--1530 mology (Schmitt and Clayton), et al.), 1373-1385 SNF proteins, S. cerevisiae, and tran- 1975-1985 Sensory organ scriptional activation (Laurent S phase, role of CLB5-a novel B cyclin development, Drosophila and Carlson), 1707-1715 (Epstein and Cross), 1695-1706 ac, sc, and emc proteins (Van Doren snRNA, U3, nuclear import of (Baserga see also yeast et al.), 2592-2605 et al.), 1120-1130 signal transduction, phosphorylation Hairless (H), protein controls SOP Somatic inhibition, Drosophila P-ele- of FUS3 kinase {Gartner et al.), cell fate (Bang and Posakony), ment pre-mRNA splicing (Sie- 1280-1292 1752-1769 bel et al.), 1386-1401

GENES & DEVELOPMENT 2683 Spindle pole body, S. cerevisiae, genes tentiates phosphorylation Tax 1 transcriptional activator and trans- involved in (Page and Snyder), (Cairns et al.), 1305-1318 forming protein, HTLV-1, inter- 1414-1429 STEI1 kinase, dominant allele potenti- action with p67 sv'v causes aber- spitz Drosophila gene, encodes putative ates phosphorylation of STE7 rant induction of cell growth EGF-like growth factor (Rut- [Cairns et al.), 1305-1318 {Fujii et al.I, 2066-2076 ledge et al.), 1503-1507 STE11. See also kinases TEF-1, homology to TEA domain of Splice site selection, 5' splice site com- Steel factor (SLF1 cytoplasmic tail, splic- Drosophila sd (Campbell et al.), petition model (Siebel et al.), ing defect and developmental 367-379 1386-1401 abnormalities {Brannan et al.), Telomere Spliceosome 1832-1842 -binding protein, MF3 [Gualberto et formation, and heat shock interference STEII kinase, S. cerevisiae, constitutive al.), 815-824 {Utans et al.), 631-641 mutants of IStevenson et al./, formation, P. primaure//a genome re- protein components of (Bennet et al.), 1293-1304 organization (Meyer), 211-222 1986-2000 Stem-loop structure, stabilizing influ- structure, RAP1 regulation of (Hardy U6 snRNA association with 5'-splice ence in E. coli mRNA (Emory et et al.}, 801-814 site of pre-mRNA (Sawa and al.), 135-148 Telomeres, S. cerevisiae, assume non- Shimura), 244-254 Stunted (stuA) gene, A. nidulans, re- nucleosomal chromatin struc- Splicing quired for cell pattern formation ture {Wright et al.), 187-210 defects, cytoplasmic tail, resulting ab- (Miller et al.), 1770-1782 Telosome, yeast chromosomal DNA, as- normalities (Brannan et al.), Subtractive hybridization, of cDNA li- sembled in non-nucleosomal 1832-1842 braries (Rothstein et al.), 1190- chromatin structure {Wright et factors 1201 al.), 187-210 human ASF/SF2, Drosophila RNA- sunY intron, bacteriophage T4 (Michel et Template supercoiling, role in N4 early binding protein RBP1 shows al.), 1373-1385 promoter activation {Mark- functional similarity to (Kim et Supercoiling (negativel, yeast rRNA iewicz et al.), 2010--2019 al.), 2569-2578 transcription initiation (Schultz Tenascin extracellular matrix protein, SLU7, 3' splice site choice in yeast et al.), 1332-1341 normal development of TN-de- (Frank and Guthrie), 2112-2124 Supercoiling. See also template super- ficient mice (Saga et al.), 1821- SR proteins, conserved family coiling 1831 (Zahler et al.), 837-847 SV40 T antigen, inhibits wild-type p53 Termination/attenuation, block to tran- inhibition, by nonsense mutations binding (Bargonetti et al.), scriptional elongation in c-myc (Naeger et al.), 1107-1119 1886-1898 gene (Krumm et al.), 2201-2213 mechanism, spliceosome and prespli- SWI4 RNA accumulation, S. cerevisiae TFIIA and IID, assembly of closed com- ceosome, protein components late G~, SIT4 protein phos- plex (Wang et al.), 1716-1727 associated with (Bennet et al.), phatase required for {Fernandez- TFIIB-related factor, BRF 1, involvement 1986-2000 Sarabia et al.), 2417-2428 in RNA Pol III transcription mitochondrial group I introns {Guo SW15, yeast transcriptional activator (Colbert and Hahn), 1940-1949 and Lambowitz), 1357-1372 {Dohrmann et al.), 93-104 Spore viability, Dictyoste//um, and dis- TFIID T ruption of spiA gene (Richarson binding, to nucleosome, failure to sup- and Loomis), 1058-1070 T/E1A-binding domain, the RB 'pocket' port vs support of transcription initiation (Lorch et al.), 2282- Sporulation (Qin et al.), 953-964 Dictyoste//um, and disruption of spiA Tat HIV- 1 2287 gene (Richarson and Loomis), in vitro processivity factor (Kato et al.), holo--TFIID, supports activation by di- 1058-1070 655-666 verse activators and TATA-less pathways, N. crassa, con gene expres- protein, activation domain inter- promoter (Zhou et al.), 1964- sion {Springer and Yanofsky), changeable with VP16 (Tiley et 1974 1052-1057 al.), 2077-2087 interaction with TATA-containing SPT3, S. cerevisiae, interaction with TATA box and TATA-lacking promoters TFIID {Eisenmann et al.), 1319- -binding (Colgan and Marfley), 304-315 1331 polypeptide {TBP), part of holo- S. cerevisiae, SPT3 interaction {Eisen- SR proteins, pre-mRNA splicing factors, TFIID complex (Zhou et al.I, mann et al.), 1319-1331 conserved family (Zahler et al.), 1964-1974 yeast and human, fianctional equiva- 837-847 protein complex, TBF-TAT complex lent of (Kelleher III et al.), 296- SSL1 supressor gene, yeast, role in DNA hSL1 (Jantzen et al.), 1950-1963 303 repair and/or translation initia- chick 13-globin gene, interaction with TFIIF, transcription elongation factor, in tion {Yoon et al.), 2463-2477 cGATA-1 (Fong et al.), 521-532 conjunction with Tat (Kato et Stalk formation, Caulobacter, role of 0 "54 protected from KMnO 4 by TBP com- al.), 655-666 factor (Brun and Shapiro), 2395- ponent of TFIID (Giardina et 3' splice site selection, yeast, mediated 2408 al.), 2190-2200 by splicing factor SLU7 (Frank Starvation, E. co//, DNA-binding protein TFIID binding to {Lorch et al.), 2282- and Guthrie), 2112-2124 Dps (Almir6n et al.), 2646-2654 2287 3T3-L 1 preadipocyte differentiation, role Stationary phase of E. coli, role of DNA- TATA-less promoter, holo-TFIID sup- of antisense C/EBP RNA (Lin binding protein Dps (Almir6n et ports transcriptional stimula- and Lanel, 533-544 al.), 2646-2654 tion from (Zhou et al.), 1964- Tissue specific STE7 kinase, dominant STE11 allele po- 1974 diversity, maize B gene and anthocya-

2684 GENES & DEVELOPMENT nm production (Radicella et al.), through START (Marini and and EVE {Johnson and Kras- 2152-2164 Reed), 557-567 now), 2177-2189 expression, Adh, conserved regulatory yeast and human TFIIDs, functional Drosophila, TFIID--promoter inter- unit in Drosophila and man equivalent of (Kelleher III et al.}, action (Colgan and Manley), (Falb and Maniatis), 454--465 296-303 304-315 mechanism, conservation between activators SWl5/HO and ACE2/CTS1, parallel Drosophila and man (Abel et GAL4 and Bicoid, dependence on pathways (Dohrmann et al.), al.), 466-480 SNF proteins (Laurent and Carl- 93-104 Tobacco, transgenic plant system, struc- son), 1707-1715 repression, Drosophila, by su(Hw) ture/function relationship of SNF and SWI yeast proteins alter (Geyer and Corces), 1865-1873 phyA (Stockhaus et al.), 2364- chromatin structure (Hir- silencing, RAP1-RIF1 involvement 2372 schhom et al.), 2288-2298 {Hardy et al.), 801-814 Toll gene, Drosophila, role in regulating antirepression, by GAL4-VP 16 termination cell localization (Norris and {Croston et al.), 2270-2281 E. coli S 10 operon, r-protein L4 and Manley), 1654-1667 enhancers, models of mechanism of transcription factor NusA have Topoisomerases yeast, inactivation of action (Geyer and Corces), separable roles (Zengel and Lin- and transcription by RNA poly- 1865-1873 dahl), 2655-2662 merase I (Schultz et al.), 1332- elongation, blocking of in human factor-dependent (Roberts et al.), 1341 c-myc gene (Krumm et al.), 1562-1574 Tracking, V(D)J recombination {Gauss 2201-2213 negative regulation (Dubendorff et al.), and Lieber/, 1553--1561 factor 2524-2535 Transcript cleavage, and elongation fac- complex, NF-KB in (Ruben et al.), phosphorylation of RNAP II CTD hep- tor SII (Izban and Luse), 1342- 730-744 tapeptide repeats (Peterson et 1356 Drosophila, CREB/ATF family (Abel al.), 426-438 Trans-activation et al.), 466-480 yeast domain, in FosB but not FosB2 (Wis- evolutionary conservation, encoded rRNA, negative supercoiling and dom et al.), 667-675 by Drosophila sd gene (Camp- topoisomerases (Schultz et al.), ets family members have different bell et al.), 367-379 1332-1341 properties (Wasylyk et al.}, 965- IIB {dTFIIB), Drosophila, analysis of TFIID/SPT3 interaction (Eisenmann 974 (Wampler and Kadonaga), 1542- et al.), 1319-1331 HW-1 Tat, mechanism of (Kato et al.), 1552 Transformation 655-666 factor NF-KB, NLS/IKB interaction biphasic effect of Max protein on Myc Trans-activator (Beg et al.), 1899-19t3 cotransformation (Prendergast papillomavirus E2 protein (Prakash et paired domain, BSAP (Adams et al.), et al.), 2429-2439 al.), 105-116 1589-1607 as distinct from immortalization (Ul- Vpl6 and Tat, interchangeable activa- RARa, role in hematopoietic differ- rich et al.), 876-887 tion domains (Tiley et al.I, entiation {Tsai et al.l, 2258- by FosB but not FosB2 {Wisdom et al.), 2077-2087 2269 667-675 pathway, Myc/Max compleses Transcription see also E2F transcription factor (Mukherjee et al.), 1480-1492 activation factors Transforming protein Tax 1, HTLV- 1, in- adenovirus Ela protein represses C/EBP and LAP, dominant-negative teraction with p67 s~ (Fujii et HLH protein Myf-5 (Braun et inhibitor of transcription (Ron al.), 2066-2076 al.), 888-902 and Habener), 439--453 Transgenic mice domains, of hUBF (Jantzen et al.), C/EBP mechanism of action (Milos activated int-3 locus {Jhappen et al.), 1950-1963 and Zaret), 991-1004 345-355 encoded by maize B gene (Goff et junB and c-jun, functional role in fi- c-myc-bearing (Benvenisty et al.), al.), 864-875 brosarcoma development (Bos- 2513--2523 HOB motifs of Fos and lun (Suther- sy-Wetzel et al.), 2340-2351 effects of TNFa {Cheng et al.), 1444- land et al.), 1810-1819 muscle-specific {Yu et al.}, 1783- 1456 holo-TFIID complex and diverse ac- 1798 entire 70-kb human [3-globin locus in- tivator domain interaction stage-specific, globin gene (Foley troduced in (Stouboulis et al.), (Zhou et al.), 1964-1974 and Engel), 730-744 1857-1864 of N4 early promoter by supercoil- initiation, closed complex requiring prion replication iHecker et al.), 1213- ing and SSB (Markiewicz et al.), acidic activator GAL4-AH, and 1228 2010-2019 TFIIA and IID (Wang et al.), Transgenic zebrafish, HOX promoter ac- by NF-KB subunits (Fujita et al.), 1716-1727 tivation (Westerfield et al.), 775-787 regulation 591-598 repression of by Fos and Jun (Li et Adh gene, conserved regulatory unit Translation initiation, yeast, role of al.), 676-689 in Drosophila and man (Falb SSL1 gene product (Yoon et al.), S. cerevisiae, SNF proteins function and Maniatis), 454--465 2463-2477 coordinately with GAL4 and Bi- and composite response elements Translational cold (Laurent and Carlson), (Miner and Yamamoto), 2491- activation, of c-myc 1 {Hannet al.), 1707-1715 2501 1229-1240 Saccharomyces G~-specific genes, Drosophila, differential regulation control cdc28 kinase and passage by homeo domain proteins UBX of Drosophila hunchback gene, by

GENES & DEVELOPMENT 2685 cooperation of Pumilio and interact with (Frank and Guth- midblastula transition (MBT), tran- Nanos activity (Barker et al.), rie), 2112-2124 scriptional activation (Lund and 2312-2326 U6 snRNA, as catalytic element in spli- Dahlberg), 1097-1106 of maternal mRNAs (Sall6s et al.), ceosome (Sawa and Shimura), Xenopus oocytes, nuclear imprint of U3 1202-1212 244--254 snRNA {Baserga et al.), 1120- X. laevis, activation of masked Ultrabithorax (Ubx) 1130 mRNAs by cytoplasmic poly(A) Drosophila, homeo domain protein Xlim-I homeo box gene, X. laevis LIM elongation (Simon et al.), 2580- UBX (Johnson and Krasnow), domain (Taira et al.), 356-366 2591 2177-2189 coupling, bacteriophage P1 and P7, c4 promoter activation, by nonessential RNA controlled expression of zeste gene (Laney and Biggin), Y ant gene (Biere et al.}, 2409- 1531-1541 Yeast 2416 UV deadenylation, 3'-UTR dependent frameshifting, E. coli dnaX gene cross-linking, U6 snRNA associated (Lowell et al.), 2088-2099 (Tsuchihashi and Brown), 511- with 5'-splice site of pre-mRNA GCN4, as probe for oncogenesis by 519 {Sawa and Shimura), 244-254 AP-I transcription factor (Oliv- initiation, internal ribosome binding resistance, yeast, affected by SSL1 iero et al.), 1799-1809 (OH et al.), 1643-1653 gene (Yoon et al.), 2463-2477 tRNA genes, yeast, targets for Ty3 inte- HAP1 activator, cofactor interaction gration (Chalker and Sand- (Turcotte and Guarente), 2001- V meyer), 117-128 2009 MFA2 gene, deadenylation of tran- tRNA, relationship to Group I introns V(D)J recombination, deletional vs. in- scripts {Muhlard and Parker), (Guo and Lambowitz), 1357- versional (Gauss and Lieber), 2100-2111 1372 1553-1561 parallel pathways of gene regulation Tumor necrosis factor a (TNFa), effects v-Ras, down-regulates nuclear PICA (Dohrmann et al.), 93-104 of in transgenic mice (Cheng et {Gallo et al.), 1621-1630 pheromone response pathway, compo- al.), 1444-1456 Vaccinia virus, poly(A) tail length (Ger- nents order of action (Cairns et Tumor progression factors, junB and shon and Moss), 1575-1586 al.), 1305-1318 c-jun (Bossy-Wetzel et al.}, Vector, gene trap pGT4,5 in mouse ES rRNA transcription, negative super- 2340-2351 cells (Skames et al.), 903-918 coiling and topoisomerase ac- Ty3, integration, RNA polymerase III Vectors, promoter trap, gene disruption tivity (Schultz et al.), 1332- transcription initiation region in ES cells (yon Melchner et al.), 1341 (Chalker and Sandmeyer), 117- 919-927 see also Saccharomyces cerevisiae 128 Virion production, in vitro using raft cul- TFIIB-related factor BRF1, RNA Pol III Tyrosine metabolism, lethal albino mice tures (Dollard et al.), 1131-1142 transcription (Colbert and (Ruppert et al.), 1430-1443 Viviparous-1 gene, maize seed matura- Hahn), 1940-1949 Tyrosyl-tRNA synthetase, binds the in- tion, activation of the C1 gene TFIID, functional equivalent of (Kelle- tron core (Guo and Lambowitz), (Hattori et al.), 609-618 her III et al.), 296-303 1357-1372 VP16 transcription activators, SNF2/SWI2 activates transcription from RNA tar- and SNF5 alter chromatin struc- get (Tiley et al.), 2077-2087 ture (Hirschhorn et al.), 2288- -induced positive control, transferred U 2298 from Oct-1 to Oct-2 by amino Ty3 targets Pol III-transcribed genes U1 snRNA, X. laevis genes, transcrip- acid exchange (Lai et al.), 2058- (Chalker and Sandmeyer), 117- tional activation at MBT (Lund 2065 128 and Dahlberg}, 1097-1106 protein, and Oct-1 multiprotein com- YG023 gene, yeast, repeated motifs sim- U1 snRNP plex (C1), protein-protein inter- ilar to Drosophila Pumilio binding to pseudo and accurate 5' actions (Pomerantz et al.), (Barker et al.), 2312-2326 splice site (Siebel et al.), 1386- 2047-2057 1401 targets splicing factor U2AF65 to 3' splice site (Hoffman and W Z Grabowski), 2554-2568 Wing development, Drosophila ap LIM zeste Drosophila gene, and activation of U2AF65 3' splicing factor, interaction gene Cohen et al.), 715-729 Ubx promoter (Laney and Big- with U1 snRNP (Hoffman and gin), 1531-1541 Grabowski), 2554-2568 Zinc finger X U3 snRNA, nuclear import, molecular protein signals for (Baserga et al.), 1120- Xenopus laevis encoded by Drosophila qpp gene, 1130 blastopore lip-specific gene, fork head oocyte nucleus localization U4/U6/U5 triple snRNP complex, entry domain (Dirksen et al.), (S6galat et al.), 1019-1029 into spliceosome (Utans et al.), 599-608 Drosophila su(Hw), transcriptional 631-641 development, poly(A) elongation and repression (Geyer and Corces), U5 snRNP (mammalian,), site-specific translational activation (Simon 1865-1873 cross-linking to 5' splice site et al.), 2580-2591 region, yeast regulators SW15 and (Wyatt et al.), 2542-2553 LIM domain, homeo box gene XIim-1 ACE2 (Dohrmann et al.), U5 yeast snRNA, SLU4 and SLU7 genes (Taira et al.), 356-366 93-104

2686 GENES & DEVELOPMENT The incisive review and discussion journal covering advances throughout molecular, cellular and developmental biology

"'file style is live@ the articles in)brmative and not too long, and tlle whole is eminenth' readable. It should beconte very use.lit/in the teaching of many aspects" of biolog3; est)ecially in making re('ent advances easily accessible to students." TIMES HIGHER EDUCATIONAL SUPPLEMENT Some Forthcoming Articles What determines whether chromosomes segregate reductionally or equationally in meiosis? by Giora Simchen and Yasser Hugerat Cyclin synthesis: Who needs it? byJeremy Minshull Steel factor and c-Kit receptor: From mutants to a growth factor system by Kathleen Morrison-Grahame and Yoshiko Takahashi RNA processing in prokaryotic cells by David Apirion and Andras Miczak Bending of DNA by transcription factors by Peter c. van der Vliet and C. Peter Verrijzer In pursuit of the functions of the Wntfamily of developmental Published monthly, BioEssavs covers advances in the fields of regulators: Insights from Xenopus laevis by Randall T. Moon genetics, molecular biology, evolutionary studies, cellular biology Interaction of rhodopsin with the G-protein, transducin by Paul A. and developmental biology. Designed to be of use both to researchers Hargrave, Heidi E. Hamm and K. P. Hoffman Exploitation of host signal transduction pathways and cytoskeletal and university teachers, the journal contains both informative, in- functions by invasive bacteria by I. Rosenshine and B. Brett Finlay depth reviews and stimulating discussions and hypotheses about The assembly of signalling complexes by receptor tyrosine kinases major biological problems. Increasingly, BioEssavs is being by George Panayotou and Michael D. Waterfield recognized as a teaching resource for both undergraduate and RNA editing: Exploring one mode with apolipoprotein B mRNA by graduate students. It is also becoming one of the most cited general Lawrence Chan The evolutionary history of the first three enzymes in pyrimidine biology journals in the literature. biosynthesis by Jeffrey N. Davidson, Kuey C. Chen, Robert S. If you would either like to receive a sample copy or to enter a Jamison, Lisa A. Musmanno and Christine B. Kern subscription for 1993 now, please fill out and return the coupon below. Fine tuning of DNA repair in transcribed genes: Mechanisms, Subscribers for 1993 will receive a complimentary copy of our special prevalence and consequences by C. Stephen Downes, Anderson J. issue on evolution and development, published in April of this year, Ryan and Robert T. Johnson Retinoic acid and mammalian craniofacial development: Molecules while stocks last. and morphogenesis by Gillian Morriss-Kay ......

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