Use of High-Risk Medications in the Elderly Emeasure 156 Emeasure 6.4.000 Identifier Version (Measure Number Authoring Tool)

Home , Dexchlorpheniramine

eMeasure Title Use of High-Risk Medications in the Elderly eMeasure 156 eMeasure 6.4.000 Identifier Version (Measure number Authoring Tool)

NQF Number 0022 GUID a3837ff8-1abc-4ba9- 800e-fd4e7953adbd

Measurement January 1, 20XX through December 31, 20XX Period

Measure Steward National Committee for Quality Assurance

Measure National Committee for Quality Assurance Developer

Endorsed By National Quality Forum

Description Percentage of patients 65 years of age and older who were ordered high-risk medications. Two rates are reported. a. Percentage of patients who were ordered at least one high-risk medication. b. Percentage of patients who were ordered at least two of the same high-risk medications.

Copyright This Physician Performance Measure (Measure) and related data specifications are owned and stewarded by the Centers for Medicare & Medicaid Services (CMS). CMS contracted (Contract HHSM-500-2011- 00079C) with the National Committee for Quality Assurance (NCQA) to develop this electronic measure. NCQA is not responsible for any use of the Measure. NCQA makes no representations, warranties, or endorsement about the quality of any organization or physician that uses or reports performance measures and NCQA has no liability to anyone who relies on such measures or specifications.

Limited proprietary coding is contained in the Measure specifications for user convenience. Users of proprietary code sets should obtain all necessary licenses from the owners of the code sets. NCQA disclaims all liability for use or accuracy of any CPT or other codes contained in the specifications.

CPT(R) contained in the Measure specifications is copyright 2004-2016 American Medical Association. LOINC(R) copyright 2004-2016 Regenstrief Institute, Inc. This material contains SNOMED Clinical Terms(R) (SNOMED CT[R]) copyright 2004-2016 International Health Terminology Standards Development Organisation. ICD-10 copyright 2016 World Health Organization. All Rights Reserved.

The American Hospital Association holds a copyright to the National Uniform Billing Committee (NUBC) codes contained in the measure specifications. The NUBC codes in the specifications are included with the permission of the AHA. The NUBC codes contained in the specifications may be used by health plans and other health care delivery organizations for the purpose of calculating and reporting Measure results or using Measure results for their internal quality improvement purposes. All other uses of the NUBC codes require a license from the AHA. Anyone desiring to use the NUBC codes in a commercial product to generate Measure results, or for any other commercial use, must obtain a commercial use license directly from the AHA. To inquire about licensing, contact [email protected]. Disclaimer The performance Measure is not a clinical guideline and does not establish a standard of medical care, and has not been tested for all potential applications. THE MEASURE AND SPECIFICATIONS ARE PROVIDED "AS IS" WITHOUT WARRANTY OF ANY KIND.

Due to technical limitations, registered trademarks are indicated by (R) or [R] and unregistered trademarks are indicated by (TM) or [TM].

Measure Scoring Proportion

Measure Type Process

Stratification None

Risk Adjustment None

Rate None Aggregation

Rationale Seniors receiving inappropriate medications are more likely to report poorer health status at follow-up, compared to seniors who receive appropriate medications (Fu, Liu, and Christensen 2004. A study of the prevalence of potentially inappropriate medication use in older adults found that 40 percent of individuals 65 and older filled at least one prescription for a potentially inappropriate medication and 13 percent filled two or more (Fick et al. 2008). While some adverse drug events are not preventable, studies estimate that between 30 and 80 percent of adverse drug events in the elderly are preventable (MacKinnon and Hepler 2003).

Reducing the number of inappropriate prescriptions can lead to improved patient safety and significant cost savings. Conservative estimates of extra costs due to potentially inappropriate medications in the elderly average $7.2 billion a year (Fu et al. 2007). Medication use by older adults will likely increase further as the U.S. population ages, new drugs are developed, and new therapeutic and preventive uses for medications are discovered (Rothberg et al. 2008). The annual direct costs of preventable adverse drug events (ADEs) in the Medicare population have been estimated to exceed $800 million (IOM, 2007). By the year 2030, nearly one in five U.S. residents is expected to be aged 65 years or older; this age group is projected to more than double in number from 38.7 million in 2008 to more than 88.5 million in 2050. Likewise, the population aged 85 years or older is expected to increase almost four-fold, from 5.4 million to 19 million between 2008 and 2050. As the elderly population continues to grow, the number of older adults who present with multiple medical conditions for which several medications are prescribed continues to increase, resulting in polypharmacy (Gray and Gardner 2009).

Clinical The measure is based on recommendations from the American Recommendation Geriatrics Society Beers Criteria for Potentially Inappropriate Medication Statement Use in Older Adults. The criteria were developed through key clinical expert consensus processes by Beers in 1997, Zahn in 2001 and an updated process by Fick in 2003, 2012 and 2015. The Beers Criteria identifies lists of drugs that are potentially inappropriate for all older adults and drugs that are potentially inappropriate in the elderly based on various high-risk factors such as dosage, days supply and underlying diseases or conditions. NCQA's Medication Management expert panel selected a subset of drugs that should be used with caution in the elderly for inclusion in the proposed measure based upon the recommendations in the Beers Criteria.

Certain medications (MacKinnon 2003) are associated with increased risk of harm from drug side-effects and drug toxicity and pose a concern for patient safety. There is clinical consensus that these drugs pose increased risks in the elderly (Kaufman 2005). Studies link prescription drug use by the elderly with adverse drug events that contribute to hospitalization, increased length of hospital stay, increased duration of illness, nursing home placement and falls and fractures that are further associated with physical, functional and social decline in the elderly (AHRQ 2009).

Improvement Lower score indicates better quality Notation

Reference Campanelli, Christine M. 2012. "American Geriatrics Society Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults: the American Geriatrics Society 2012 Beers Criteria Update Expert Panel." Journal of the American Geriatrics Society 60(4): 616.

Reference American Geriatrics Society 2015 Beers Criteria Update Expert Panel. 2015. "American Geriatrics Society 2015 Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults." Journal of the American Geriatrics Society. 63(11): 2227-2246.

Reference Zhan, C, et al. Potentially inappropriate medication use in the community-dwelling elderly. JAMA 2001; 286(22):2823-2868.

Reference Beers, M.H. Explicit criteria for determining potentially inappropriate medication use by the elderly. Arch Intern Med 1997; 157:1531-1536.

Reference Fick, DM, et al. Updating the Beers criteria for potentially inappropriate medication use in older adults. Arch Intern Med 2003; 163:2716-2724.

Reference Fu, A.Z., J.Z. Jiang, J.H. Reeves, J.E. Funcham, G.G. Liu, M. Perri. 2007. "Potentially Inappropriate Medication Use and Healthcare Expenditures in the US Community-Dwelling Elderly." Medical Care 45: 472-6.

Reference Gray, C.L, and C. Gardner. 2009. "Adverse Drug Events in the Elderly: An Ongoing Problem." J Manag Care Pharm 15(7):568-71.

Reference Fick, D.M., L.C. Mion, M.H. Beers, J.L. Waller. 2008. "Health Outcomes Associated with Potentially Inappropriate Medication Use in Older Adults." Research in Nursing & Health. 31(1): 42-51.

Reference AHRQ, "Use of High-Risk Medications in the Elderly: Percentage of Medicare Members 65 years of Age and Older who Received at least two different High-Risk Medications." National Quality Measures Clearinghouse. http://www.qualitymeasures.ahrq.gov/popups/printView.aspx?id=24003 (Accessed Web page: December 14, 2015).

Reference Institute of Medicine (IOM). 2007. Preventing Medication Errors/Committee on Identifying and Preventing Medication Errors. Ed. Aspden P., J.A. Wolcott, J.L. Bootman, L.R. Cronenwatt LR. Quality Chasm Series. Washington, DC: National Academy Press.

Reference MacKinnon, N.J. and C.D. Hepler. 2003. "Indicators of Preventable Drug-related Morbidity in Older Adults: Use Within a Managed Care Organization." J Managed Care Pharm 9:134-41.

Reference Kaufman MB, et al. Effect of Prescriber Education on the Use of Medications Contraindicated in Older Adults in a Managed Medicare Population. J Manag Care Pharm 2005 April/May; 11(3):211-219.

Reference Rothberg, M.B., P.S. Perkow, F. Liu, B. Korc-Grodzicki, M.J. Brennan, S. Bellantonio, M. Heelon, P.K. Lindenauer. 2008. "Potentially Inappropriate Medication Use in Hospitalized Elders." J Hosp Med 3:91- 102.

Definition A high-risk medication is identified by either of the following: a. A prescription for medications classified as high risk at any dose and for any duration b. Prescriptions for medications classified as high risk at any dose with greater than a 90 day supply

Guidance The intent of Numerator 1 is to assess if the patient has been prescribed at least one high-risk medication.

The intent of Numerator 2 is to assess if the patient has either: - Been prescribed at least two of the same high-risk medications. - Received two or more prescriptions, where the sum of days supply exceeds 90 days, for medications in the same medication class.

The intent of the measure is to assess if the reporting provider ordered the high-risk medication(s). If the patient had a high-risk medication previously prescribed by another provider, they would not be counted towards the numerator unless the reporting provider also ordered a high-risk medication for them.

CUMULATIVE MEDICATION DURATION is an individual's total number of medication days over a specific period; the period counts multiple prescriptions with gaps in between, but does not count the gaps during which a medication was not dispensed.

To determine the cumulative medication duration, determine first the number of the Medication Days for each prescription in the period: the number of doses divided by the dose frequency per day. Then add the Medication Days for each prescription without counting any days between the prescriptions.

For example, there is an original prescription for 30 days with 2 refills for thirty days each. After a gap of 3 months, the medication was prescribed again for 60 days with 1 refill for 60 days. The cumulative medication duration is (30 x 3) + (60 x 2) = 210 days over the 10 month period.

Transmission TBD Format

Initial Patients 65 years and older who had a visit during the measurement Population period

Denominator Equals Initial Population

Denominator Exclude patients who were in hospice care during the measurement Exclusions year

Numerator Numerator 1: Patients with an order for at least one high-risk medication during the measurement period

Numerator 2: Patients with at least two orders for the same high-risk medication during the measurement period

Numerator Not Applicable Exclusions

Denominator None Exceptions Supplemental For every patient evaluated by this measure also identify payer, race, Data Elements ethnicity and sex

Table of Contents

• Population Criteria • Data Criteria (QDM Variables) • Data Criteria (QDM Data Elements) • Supplemental Data Elements • Risk Adjustment Variables

Population Criteria

• ------Population Criteria 1 ------

• Initial Population = o AND: Age>= 65 year(s) at: "Measurement Period" o AND: Union of: ▪ "Encounter, Performed: Office Visit" ▪ "Encounter, Performed: Ophthalmologic Outpatient Visit" ▪ "Encounter, Performed: Face-to-Face Interaction" ▪ "Encounter, Performed: Preventive Care Services - Established Office Visit, 18 and Up" ▪ "Encounter, Performed: Preventive Care Services-Initial Office Visit, 18 and Up" ▪ "Encounter, Performed: Annual Wellness Visit" ▪ "Encounter, Performed: Home Healthcare Services" ▪ during "Measurement Period" • Denominator = o AND: Initial Population • Denominator Exclusions = o OR: "Encounter, Performed: Encounter Inpatient (discharge status: Discharged to Home for Hospice Care)" ends during "Measurement Period" o OR: "Encounter, Performed: Encounter Inpatient (discharge status: Discharged to Health Care Facility for Hospice Care)" ends during "Measurement Period" o OR: Union of: ▪ "Intervention, Order: Hospice care ambulatory" ▪ "Intervention, Performed: Hospice care ambulatory" ▪ overlaps "Measurement Period" • Numerator = o AND: ▪ OR: "Medication, Order: High Risk Medications for the Elderly" during "Measurement Period" ▪ OR: "Medication, Order: High-Risk Medications With Days Supply Criteria (cumulative medication duration >= 90 day(s))" during "Measurement Period" • Numerator Exclusions = o None • Denominator Exceptions = o None • Stratification = o None • ------Population Criteria 2 ------• Initial Population = o AND: Age>= 65 year(s) at: "Measurement Period" o AND: Union of: ▪ "Encounter, Performed: Office Visit" ▪ "Encounter, Performed: Ophthalmologic Outpatient Visit" ▪ "Encounter, Performed: Face-to-Face Interaction" ▪ "Encounter, Performed: Preventive Care Services - Established Office Visit, 18 and Up" ▪ "Encounter, Performed: Preventive Care Services-Initial Office Visit, 18 and Up" ▪ "Encounter, Performed: Annual Wellness Visit" ▪ "Encounter, Performed: Home Healthcare Services" ▪ during "Measurement Period" • Denominator = o AND: Initial Population • Denominator Exclusions = o OR: "Encounter, Performed: Encounter Inpatient (discharge status: Discharged to Home for Hospice Care)" ends during "Measurement Period" o OR: "Encounter, Performed: Encounter Inpatient (discharge status: Discharged to Health Care Facility for Hospice Care)" ends during "Measurement Period" o OR: Union of: ▪ "Intervention, Order: Hospice care ambulatory" ▪ "Intervention, Performed: Hospice care ambulatory" ▪ overlaps "Measurement Period" • Numerator = o AND: ▪ OR: "Medication, Order: Hydrochlorothiazide / Methyldopa" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Hydrochlorothiazide / Methyldopa" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine / Ibuprofen / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine / Ibuprofen / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Carbetapentane / Chlorpheniramine / Ephedrine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Carbetapentane / Chlorpheniramine / Ephedrine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Chlorpheniramine / Dextromethorphan" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Chlorpheniramine / Dextromethorphan" during "Measurement Period" ) ▪ OR: "Medication, Order: Dexchlorpheniramine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dexchlorpheniramine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Dexbrompheniramine / Dextromethorphan / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dexbrompheniramine / Dextromethorphan / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Amitriptyline / Perphenazine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Amitriptyline / Perphenazine" during "Measurement Period" ) ▪ OR: "Medication, Order: Dexbrompheniramine Maleate / Pseudoephedrine Hydrochloride" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dexbrompheniramine Maleate / Pseudoephedrine Hydrochloride" during "Measurement Period" ) ▪ OR: "Medication, Order: Dexbrompheniramine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dexbrompheniramine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Codeine / Pseudoephedrine / Triprolidine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Codeine / Pseudoephedrine / Triprolidine" during "Measurement Period" ) ▪ OR: "Medication, Order: Codeine / Dexchlorpheniramine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Codeine / Dexchlorpheniramine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine / Dihydrocodeine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine / Dihydrocodeine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlophedianol / Dexbrompheniramine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlophedianol / Dexbrompheniramine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Codeine / Dexbrompheniramine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Codeine / Dexbrompheniramine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Dexbrompheniramine / Dextromethorphan / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dexbrompheniramine / Dextromethorphan / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine / Codeine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine / Codeine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlophedianol / Dexbrompheniramine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlophedianol / Dexbrompheniramine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Dextromethorphan / Diphenhydramine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Dextromethorphan / Diphenhydramine" during "Measurement Period" ) ▪ OR: "Medication, Order: Estradiol / Levonorgestrel" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Estradiol / Levonorgestrel" during "Measurement Period" ) ▪ OR: "Medication, Order: Brompheniramine / Chlophedianol / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Brompheniramine / Chlophedianol / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Dextromethorphan / Doxylamine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dextromethorphan / Doxylamine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Brompheniramine / Chlophedianol / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Brompheniramine / Chlophedianol / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine / Codeine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine / Codeine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlophedianol / Dexchlorpheniramine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlophedianol / Dexchlorpheniramine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Doxylamine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Doxylamine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Brompheniramine / Codeine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Brompheniramine / Codeine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Dextromethorphan / Doxylamine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dextromethorphan / Doxylamine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine / Phenylephrine / Phenyltoloxamine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine / Phenylephrine / Phenyltoloxamine" during "Measurement Period" ) ▪ OR: "Medication, Order: Brompheniramine / Codeine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Brompheniramine / Codeine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Dextromethorphan / Diphenhydramine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Dextromethorphan / Diphenhydramine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Carbetapentane / Chlorpheniramine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Carbetapentane / Chlorpheniramine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlophedianol / Chlorpheniramine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlophedianol / Chlorpheniramine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Meprobamate" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Meprobamate" during "Measurement Period" ) ▪ OR: "Medication, Order: Trimipramine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Trimipramine" during "Measurement Period" ) ▪ OR: "Medication, Order: Ergoloid Mesylates" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Ergoloid Mesylates" during "Measurement Period" ) ▪ OR: "Medication, Order: Thioridazine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Thioridazine" during "Measurement Period" ) ▪ OR: "Medication, Order: Phenobarbital" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Phenobarbital" during "Measurement Period" ) ▪ OR: "Medication, Order: Dipyridamole" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dipyridamole" during "Measurement Period" ) ▪ OR: "Medication, Order: Meperidine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Meperidine" during "Measurement Period" ) ▪ OR: "Medication, Order: Doxylamine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Doxylamine" during "Measurement Period" ) ▪ OR: "Medication, Order: Amobarbital" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Amobarbital" during "Measurement Period" ) ▪ OR: "Medication, Order: Secobarbital" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Secobarbital" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpropamide" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpropamide" during "Measurement Period" ) ▪ OR: "Medication, Order: Ticlopidine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Ticlopidine" during "Measurement Period" ) ▪ OR: "Medication, Order: Carbinoxamine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Carbinoxamine" during "Measurement Period" ) ▪ OR: "Medication, Order: Clemastine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Clemastine" during "Measurement Period" ) ▪ OR: "Medication, Order: Disopyramide" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Disopyramide" during "Measurement Period" ) ▪ OR: "Medication, Order: Estropipate" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Estropipate" during "Measurement Period" ) ▪ OR: "Medication, Order: Methyldopa" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Methyldopa" during "Measurement Period" ) ▪ OR: "Medication, Order: Trihexyphenidyl" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Trihexyphenidyl" during "Measurement Period" ) ▪ OR: "Medication, Order: Clomipramine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Clomipramine" during "Measurement Period" ) ▪ OR: "Medication, Order: Guanfacine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Guanfacine" during "Measurement Period" ) ▪ OR: "Medication, Order: Megestrol" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Megestrol" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine" during "Measurement Period" ) ▪ OR: "Medication, Order: Nifedipine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Nifedipine" during "Measurement Period" ) ▪ OR: "Medication, Order: Orphenadrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Orphenadrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Conjugated Estrogens" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Conjugated Estrogens" during "Measurement Period" ) ▪ OR: "Medication, Order: Metaxalone" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Metaxalone" during "Measurement Period" ) ▪ OR: "Medication, Order: Imipramine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Imipramine" during "Measurement Period" ) ▪ OR: "Medication, Order: Benztropine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Benztropine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorzoxazone" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorzoxazone" during "Measurement Period" ) ▪ OR: "Medication, Order: Ketorolac Tromethamine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Ketorolac Tromethamine" during "Measurement Period" ) ▪ OR: "Medication, Order: Estradiol" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Estradiol" during "Measurement Period" ) ▪ OR: "Medication, Order: Indomethacin" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Indomethacin" during "Measurement Period" ) ▪ OR: "Medication, Order: Glyburide" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Glyburide" during "Measurement Period" ) ▪ OR: "Medication, Order: Carisoprodol" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Carisoprodol" during "Measurement Period" ) ▪ OR: "Medication, Order: Methocarbamol" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Methocarbamol" during "Measurement Period" ) ▪ OR: "Medication, Order: Diphenhydramine Hydrochloride" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Diphenhydramine Hydrochloride" during "Measurement Period" ) ▪ OR: "Medication, Order: Cyclobenzaprine Hydrochloride" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Cyclobenzaprine Hydrochloride" during "Measurement Period" ) ▪ OR: "Medication, Order: Amitriptyline Hydrochloride" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Amitriptyline Hydrochloride" during "Measurement Period" ) ▪ OR: "Medication, Order: Hydroxyzine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Hydroxyzine" during "Measurement Period" ) ▪ OR: "Medication, Order: Dexbrompheniramine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dexbrompheniramine" during "Measurement Period" ) ▪ OR: "Medication, Order: Dexchlorpheniramine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dexchlorpheniramine" during "Measurement Period" ) ▪ OR: "Medication, Order: Meperidine / Promethazine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Meperidine / Promethazine" during "Measurement Period" ) ▪ OR: "Medication, Order: Pentobarbital" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Pentobarbital" during "Measurement Period" ) ▪ OR: "Medication, Order: Butabarbital" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Butabarbital" during "Measurement Period" ) ▪ OR: "Medication, Order: Pentazocine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Pentazocine" during "Measurement Period" ) ▪ OR: "Medication, Order: Triprolidine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Triprolidine" during "Measurement Period" ) ▪ OR: "Medication, Order: Mephobarbital" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Mephobarbital" during "Measurement Period" ) ▪ OR: "Medication, Order: Esterified Estrogens" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Esterified Estrogens" during "Measurement Period" ) ▪ OR: "Medication, Order: Isoxsuprine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Isoxsuprine" during "Measurement Period" ) ▪ OR: "Medication, Order: Brompheniramine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Brompheniramine" during "Measurement Period" ) ▪ OR: "Medication, Order: Amitriptyline / Chlordiazepoxide" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Amitriptyline / Chlordiazepoxide" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Dextromethorphan / Doxylamine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Dextromethorphan / Doxylamine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Chlorpheniramine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Chlorpheniramine" during "Measurement Period" ) ▪ OR: "Medication, Order: Codeine / Phenylephrine / Promethazine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Codeine / Phenylephrine / Promethazine" during "Measurement Period" ) ▪ OR: "Medication, Order: Diphenhydramine / Ibuprofen" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Diphenhydramine / Ibuprofen" during "Measurement Period" ) ▪ OR: "Medication, Order: Phenylephrine / Promethazine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Phenylephrine / Promethazine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine / Dextromethorphan" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine / Dextromethorphan" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine / Hydrocodone / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine / Hydrocodone / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Dexchlorpheniramine / Dextromethorphan / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dexchlorpheniramine / Dextromethorphan / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine / Codeine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine / Codeine" during "Measurement Period" ) ▪ OR: "Medication, Order: Aspirin / Caffeine / Orphenadrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Aspirin / Caffeine / Orphenadrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Aspirin / Carisoprodol / Codeine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Aspirin / Carisoprodol / Codeine" during "Measurement Period" ) ▪ OR: "Medication, Order: Diphenhydramine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Diphenhydramine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine / Phenylephrine / Pyrilamine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine / Phenylephrine / Pyrilamine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Chlorpheniramine / Dextromethorphan / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Chlorpheniramine / Dextromethorphan / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine / Dextromethorphan / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine / Dextromethorphan / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Aspirin / Carisoprodol" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Aspirin / Carisoprodol" during "Measurement Period" ) ▪ OR: "Medication, Order: Dextromethorphan / Promethazine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dextromethorphan / Promethazine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Chlorpheniramine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Chlorpheniramine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Butalbital" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Butalbital" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Diphenhydramine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Diphenhydramine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Esterified Estrogens / Methyltestosterone" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Esterified Estrogens / Methyltestosterone" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Chlorpheniramine / Dextromethorphan / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Chlorpheniramine / Dextromethorphan / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Aspirin / Butalbital / Caffeine / Codeine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Aspirin / Butalbital / Caffeine / Codeine" during "Measurement Period" ) ▪ OR: "Medication, Order: Estradiol / Norethindrone" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Estradiol / Norethindrone" during "Measurement Period" ) ▪ OR: "Medication, Order: Conjugated Estrogens / Medroxyprogesterone" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Conjugated Estrogens / Medroxyprogesterone" during "Measurement Period" ) ▪ OR: "Medication, Order: Brompheniramine / Dextromethorphan / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Brompheniramine / Dextromethorphan / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Butalbital / Caffeine / Codeine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Butalbital / Caffeine / Codeine" during "Measurement Period" ) ▪ OR: "Medication, Order: Brompheniramine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Brompheniramine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Chlorpheniramine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Chlorpheniramine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Dextromethorphan / Doxylamine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Dextromethorphan / Doxylamine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine / Hydrocodone" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine / Hydrocodone" during "Measurement Period" ) ▪ OR: "Medication, Order: Brompheniramine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Brompheniramine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Trimethobenzamide" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Trimethobenzamide" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine / Dextromethorphan / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine / Dextromethorphan / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Dextromethorphan / Doxylamine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Dextromethorphan / Doxylamine" during "Measurement Period" ) ▪ OR: "Medication, Order: Brompheniramine / Dextromethorphan / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Brompheniramine / Dextromethorphan / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Codeine / Promethazine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Codeine / Promethazine" during "Measurement Period" ) ▪ OR: "Medication, Order: Chlorpheniramine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Chlorpheniramine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Pseudoephedrine / Triprolidine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Pseudoephedrine / Triprolidine" during "Measurement Period" ) ▪ OR: "Medication, Order: Naloxone / Pentazocine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Naloxone / Pentazocine" during "Measurement Period" ) ▪ OR: "Medication, Order: Aspirin / Butalbital / Caffeine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Aspirin / Butalbital / Caffeine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Diphenhydramine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Diphenhydramine" during "Measurement Period" ) ▪ OR: "Medication, Order: Desiccated Thyroid" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Desiccated Thyroid" during "Measurement Period" ) ▪ OR: "Medication, Order: Atropine / Hyoscyamine / Phenobarbital / Scopolamine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Atropine / Hyoscyamine / Phenobarbital / Scopolamine" during "Measurement Period" ) ▪ OR: "Medication, Order: Glyburide / Metformin" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Glyburide / Metformin" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Butalbital / Caffeine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Butalbital / Caffeine" during "Measurement Period" ) ▪ OR: "Medication, Order: Promethazine Hydrochloride" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Promethazine Hydrochloride" during "Measurement Period" ) ▪ OR: "Medication, Order: Aspirin / Diphenhydramine Citrate" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Aspirin / Diphenhydramine Citrate" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Diphenhydramine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Diphenhydramine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Doxylamine / Pyridoxine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Doxylamine / Pyridoxine" during "Measurement Period" ) ▪ OR: "Medication, Order: Aspirin / Chlorpheniramine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Aspirin / Chlorpheniramine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Chlorpheniramine / Dextromethorphan / Guaifenesin" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Chlorpheniramine / Dextromethorphan / Guaifenesin" during "Measurement Period" ) ▪ OR: "Medication, Order: Dexbrompheniramine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dexbrompheniramine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Phenylephrine / Triprolidine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Phenylephrine / Triprolidine" during "Measurement Period" ) ▪ OR: "Medication, Order: Bazedoxifene / Conjugated Estrogens" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Bazedoxifene / Conjugated Estrogens" during "Measurement Period" ) ▪ OR: "Medication, Order: Doxylamine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Doxylamine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Aspirin / Diphenhydramine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Aspirin / Diphenhydramine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Brompheniramine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Brompheniramine" during "Measurement Period" ) ▪ OR: "Medication, Order: Diphenhydramine / Pseudoephedrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Diphenhydramine / Pseudoephedrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Aspirin / Meprobamate" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Aspirin / Meprobamate" during "Measurement Period" ) ▪ OR: "Medication, Order: Diphenhydramine / Magnesium Salicylate" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Diphenhydramine / Magnesium Salicylate" during "Measurement Period" ) ▪ OR: "Medication, Order: Estradiol / Norgestimate Biphasic" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Estradiol / Norgestimate Biphasic" during "Measurement Period" ) ▪ OR: "Medication, Order: Dextromethorphan / Diphenhydramine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dextromethorphan / Diphenhydramine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Dienogest / Estradiol Multiphasic" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dienogest / Estradiol Multiphasic" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Doxylamine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Doxylamine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Dexchlorpheniramine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Dexchlorpheniramine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Acetaminophen / Dexbrompheniramine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Acetaminophen / Dexbrompheniramine" during "Measurement Period" ) ▪ OR: "Medication, Order: Diphenhydramine / Naproxen" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Diphenhydramine / Naproxen" during "Measurement Period" ) ▪ OR: "Medication, Order: Brompheniramine / Codeine / Phenylephrine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Brompheniramine / Codeine / Phenylephrine" during "Measurement Period" ) ▪ OR: "Medication, Order: Drospirenone / Estradiol" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Drospirenone / Estradiol" during "Measurement Period" ) ▪ OR: "Medication, Order: Atropine / Chlorpheniramine / Hyoscyamine / Pseudoephedrine / Scopolamine" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Atropine / Chlorpheniramine / Hyoscyamine / Pseudoephedrine / Scopolamine" during "Measurement Period" ) ▪ OR: ▪ AND: Sum>= 90 day(s): "Medication, Order: Nonbenzodiazepine hypnotics (cumulative medication duration)" during "Measurement Period" ▪ AND: "Medication, Order: Nonbenzodiazepine hypnotics" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Nonbenzodiazepine hypnotics" during "Measurement Period" ) ▪ OR: ▪ AND: Sum>= 90 day(s): "Medication, Order: Anti Infectives, other (cumulative medication duration)" during "Measurement Period" ▪ AND: "Medication, Order: Anti Infectives, other" satisfies all: ▪ during "Measurement Period" ▪ >= 1 day(s) starts after end of ("Medication, Order: Anti Infectives, other" during "Measurement Period" ) • Numerator Exclusions = o None • Denominator Exceptions = o None • Stratification = o None

Data Criteria (QDM Variables) • None

Data Criteria (QDM Data Elements)

• "Encounter, Performed: Annual Wellness Visit" using "Annual Wellness Visit Grouping Value Set (2.16.840.1.113883.3.526.3.1240)" • "Encounter, Performed: Encounter Inpatient" using "Encounter Inpatient SNOMEDCT Value Set (2.16.840.1.113883.3.666.5.307)" • "Encounter, Performed: Face-to-Face Interaction" using "Face-to-Face Interaction Grouping Value Set (2.16.840.1.113883.3.464.1003.101.12.1048)" • "Encounter, Performed: Home Healthcare Services" using "Home Healthcare Services Grouping Value Set (2.16.840.1.113883.3.464.1003.101.12.1016)" • "Encounter, Performed: Office Visit" using "Office Visit Grouping Value Set (2.16.840.1.113883.3.464.1003.101.12.1001)" • "Encounter, Performed: Ophthalmologic Outpatient Visit" using "Ophthalmologic Outpatient Visit CPT Value Set (2.16.840.1.113883.3.464.1003.101.11.1206)" • "Encounter, Performed: Preventive Care Services - Established Office Visit, 18 and Up" using "Preventive Care Services - Established Office Visit, 18 and Up Grouping Value Set (2.16.840.1.113883.3.464.1003.101.12.1025)" • "Encounter, Performed: Preventive Care Services-Initial Office Visit, 18 and Up" using "Preventive Care Services-Initial Office Visit, 18 and Up Grouping Value Set (2.16.840.1.113883.3.464.1003.101.12.1023)" • "Intervention, Order: Hospice care ambulatory" using "Hospice care ambulatory SNOMEDCT Value Set (2.16.840.1.113762.1.4.1108.15)" • "Intervention, Performed: Hospice care ambulatory" using "Hospice care ambulatory SNOMEDCT Value Set (2.16.840.1.113762.1.4.1108.15)" • "Medication, Order: Acetaminophen / Aspirin / Diphenhydramine" using "Acetaminophen / Aspirin / Diphenhydramine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1388)" • "Medication, Order: Acetaminophen / Brompheniramine" using "Acetaminophen / Brompheniramine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1389)" • "Medication, Order: Acetaminophen / Butalbital" using "Acetaminophen / Butalbital Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1317)" • "Medication, Order: Acetaminophen / Butalbital / Caffeine" using "Acetaminophen / Butalbital / Caffeine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1363)" • "Medication, Order: Acetaminophen / Butalbital / Caffeine / Codeine" using "Acetaminophen / Butalbital / Caffeine / Codeine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1326)" • "Medication, Order: Acetaminophen / Chlorpheniramine" using "Acetaminophen / Chlorpheniramine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1289)" • "Medication, Order: Acetaminophen / Chlorpheniramine / Dextromethorphan" using "Acetaminophen / Chlorpheniramine / Dextromethorphan Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1421)" • "Medication, Order: Acetaminophen / Chlorpheniramine / Dextromethorphan / Guaifenesin" using "Acetaminophen / Chlorpheniramine / Dextromethorphan / Guaifenesin Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1383)" • "Medication, Order: Acetaminophen / Chlorpheniramine / Dextromethorphan / Phenylephrine" using "Acetaminophen / Chlorpheniramine / Dextromethorphan / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1310)" • "Medication, Order: Acetaminophen / Chlorpheniramine / Dextromethorphan / Pseudoephedrine" using "Acetaminophen / Chlorpheniramine / Dextromethorphan / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1321)" • "Medication, Order: Acetaminophen / Chlorpheniramine / Phenylephrine" using "Acetaminophen / Chlorpheniramine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1328)" • "Medication, Order: Acetaminophen / Chlorpheniramine / Pseudoephedrine" using "Acetaminophen / Chlorpheniramine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1316)" • "Medication, Order: Acetaminophen / Dexbrompheniramine" using "Acetaminophen / Dexbrompheniramine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1405)" • "Medication, Order: Acetaminophen / Dextromethorphan / Diphenhydramine" using "Acetaminophen / Dextromethorphan / Diphenhydramine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1441)" • "Medication, Order: Acetaminophen / Dextromethorphan / Diphenhydramine / Phenylephrine" using "Acetaminophen / Dextromethorphan / Diphenhydramine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1399)" • "Medication, Order: Acetaminophen / Dextromethorphan / Doxylamine" using "Acetaminophen / Dextromethorphan / Doxylamine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1338)" • "Medication, Order: Acetaminophen / Dextromethorphan / Doxylamine / Phenylephrine" using "Acetaminophen / Dextromethorphan / Doxylamine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1287)" • "Medication, Order: Acetaminophen / Dextromethorphan / Doxylamine / Pseudoephedrine" using "Acetaminophen / Dextromethorphan / Doxylamine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1329)" • "Medication, Order: Acetaminophen / Diphenhydramine" using "Acetaminophen / Diphenhydramine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1350)" • "Medication, Order: Acetaminophen / Diphenhydramine / Phenylephrine" using "Acetaminophen / Diphenhydramine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1318)" • "Medication, Order: Acetaminophen / Diphenhydramine / Pseudoephedrine" using "Acetaminophen / Diphenhydramine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1378)" • "Medication, Order: Acetaminophen / Doxylamine / Phenylephrine" using "Acetaminophen / Doxylamine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1400)" • "Medication, Order: Amitriptyline / Chlordiazepoxide" using "Amitriptyline / Chlordiazepoxide Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1286)" • "Medication, Order: Amitriptyline / Perphenazine" using "Amitriptyline / Perphenazine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1428)" • "Medication, Order: Amitriptyline Hydrochloride" using "Amitriptyline Hydrochloride Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1373)" • "Medication, Order: Amobarbital" using "Amobarbital Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1297)" • "Medication, Order: Anti Infectives, other" using "Anti Infectives, other Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1481)" • "Medication, Order: Aspirin / Butalbital / Caffeine" using "Aspirin / Butalbital / Caffeine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1347)" • "Medication, Order: Aspirin / Butalbital / Caffeine / Codeine" using "Aspirin / Butalbital / Caffeine / Codeine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1322)" • "Medication, Order: Aspirin / Caffeine / Orphenadrine" using "Aspirin / Caffeine / Orphenadrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1302)" • "Medication, Order: Aspirin / Carisoprodol" using "Aspirin / Carisoprodol Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1313)" • "Medication, Order: Aspirin / Carisoprodol / Codeine" using "Aspirin / Carisoprodol / Codeine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1305)" • "Medication, Order: Aspirin / Chlorpheniramine / Phenylephrine" using "Aspirin / Chlorpheniramine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1380)" • "Medication, Order: Aspirin / Diphenhydramine Citrate" using "Aspirin / Diphenhydramine Citrate Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1376)" • "Medication, Order: Aspirin / Meprobamate" using "Aspirin / Meprobamate Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1394)" • "Medication, Order: Atropine / Chlorpheniramine / Hyoscyamine / Pseudoephedrine / Scopolamine" using "Atropine / Chlorpheniramine / Hyoscyamine / Pseudoephedrine / Scopolamine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1411)" • "Medication, Order: Atropine / Hyoscyamine / Phenobarbital / Scopolamine" using "Atropine / Hyoscyamine / Phenobarbital / Scopolamine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1355)" • "Medication, Order: Bazedoxifene / Conjugated Estrogens" using "Bazedoxifene / Conjugated Estrogens Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1386)" • "Medication, Order: Benztropine" using "Benztropine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1361)" • "Medication, Order: Brompheniramine" using "Brompheniramine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1427)" • "Medication, Order: Brompheniramine / Chlophedianol / Phenylephrine" using "Brompheniramine / Chlophedianol / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1445)" • "Medication, Order: Brompheniramine / Chlophedianol / Pseudoephedrine" using "Brompheniramine / Chlophedianol / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1443)" • "Medication, Order: Brompheniramine / Codeine" using "Brompheniramine / Codeine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1455)" • "Medication, Order: Brompheniramine / Codeine / Phenylephrine" using "Brompheniramine / Codeine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1409)" • "Medication, Order: Brompheniramine / Codeine / Pseudoephedrine" using "Brompheniramine / Codeine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1450)" • "Medication, Order: Brompheniramine / Dextromethorphan / Phenylephrine" using "Brompheniramine / Dextromethorphan / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1325)" • "Medication, Order: Brompheniramine / Dextromethorphan / Pseudoephedrine" using "Brompheniramine / Dextromethorphan / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1339)" • "Medication, Order: Brompheniramine / Phenylephrine" using "Brompheniramine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1327)" • "Medication, Order: Brompheniramine / Pseudoephedrine" using "Brompheniramine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1332)" • "Medication, Order: Butabarbital" using "Butabarbital Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1402)" • "Medication, Order: Carbetapentane / Chlorpheniramine / Ephedrine / Phenylephrine" using "Carbetapentane / Chlorpheniramine / Ephedrine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1420)" • "Medication, Order: Carbetapentane / Chlorpheniramine / Phenylephrine" using "Carbetapentane / Chlorpheniramine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1472)" • "Medication, Order: Carbinoxamine" using "Carbinoxamine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1306)" • "Medication, Order: Carisoprodol" using "Carisoprodol Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1369)" • "Medication, Order: Chlophedianol / Chlorpheniramine / Phenylephrine" using "Chlophedianol / Chlorpheniramine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1412)" • "Medication, Order: Chlophedianol / Dexbrompheniramine / Phenylephrine" using "Chlophedianol / Dexbrompheniramine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1435)" • "Medication, Order: Chlophedianol / Dexbrompheniramine / Pseudoephedrine" using "Chlophedianol / Dexbrompheniramine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1440)" • "Medication, Order: Chlophedianol / Dexchlorpheniramine / Pseudoephedrine" using "Chlophedianol / Dexchlorpheniramine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1447)" • "Medication, Order: Chlorpheniramine" using "Chlorpheniramine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1352)" • "Medication, Order: Chlorpheniramine / Codeine" using "Chlorpheniramine / Codeine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1301)" • "Medication, Order: Chlorpheniramine / Codeine / Phenylephrine" using "Chlorpheniramine / Codeine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1439)" • "Medication, Order: Chlorpheniramine / Codeine / Pseudoephedrine" using "Chlorpheniramine / Codeine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1446)" • "Medication, Order: Chlorpheniramine / Dextromethorphan" using "Chlorpheniramine / Dextromethorphan Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1296)" • "Medication, Order: Chlorpheniramine / Dextromethorphan / Phenylephrine" using "Chlorpheniramine / Dextromethorphan / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1312)" • "Medication, Order: Chlorpheniramine / Dextromethorphan / Pseudoephedrine" using "Chlorpheniramine / Dextromethorphan / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1337)" • "Medication, Order: Chlorpheniramine / Dihydrocodeine / Phenylephrine" using "Chlorpheniramine / Dihydrocodeine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1434)" • "Medication, Order: Chlorpheniramine / Hydrocodone" using "Chlorpheniramine / Hydrocodone Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1330)" • "Medication, Order: Chlorpheniramine / Hydrocodone / Pseudoephedrine" using "Chlorpheniramine / Hydrocodone / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1299)" • "Medication, Order: Chlorpheniramine / Ibuprofen / Pseudoephedrine" using "Chlorpheniramine / Ibuprofen / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1416)" • "Medication, Order: Chlorpheniramine / Phenylephrine" using "Chlorpheniramine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1343)" • "Medication, Order: Chlorpheniramine / Phenylephrine / Phenyltoloxamine" using "Chlorpheniramine / Phenylephrine / Phenyltoloxamine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1453)" • "Medication, Order: Chlorpheniramine / Phenylephrine / Pyrilamine" using "Chlorpheniramine / Phenylephrine / Pyrilamine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1309)" • "Medication, Order: Chlorpheniramine / Pseudoephedrine" using "Chlorpheniramine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1315)" • "Medication, Order: Chlorpropamide" using "Chlorpropamide Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1303)" • "Medication, Order: Chlorzoxazone" using "Chlorzoxazone Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1362)" • "Medication, Order: Clemastine" using "Clemastine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1308)" • "Medication, Order: Clomipramine" using "Clomipramine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1336)" • "Medication, Order: Codeine / Dexbrompheniramine / Pseudoephedrine" using "Codeine / Dexbrompheniramine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1437)" • "Medication, Order: Codeine / Dexchlorpheniramine / Phenylephrine" using "Codeine / Dexchlorpheniramine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1433)" • "Medication, Order: Codeine / Phenylephrine / Promethazine" using "Codeine / Phenylephrine / Promethazine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1291)" • "Medication, Order: Codeine / Promethazine" using "Codeine / Promethazine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1340)" • "Medication, Order: Codeine / Pseudoephedrine / Triprolidine" using "Codeine / Pseudoephedrine / Triprolidine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1431)" • "Medication, Order: Conjugated Estrogens" using "Conjugated Estrogens Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1357)" • "Medication, Order: Conjugated Estrogens / Medroxyprogesterone" using "Conjugated Estrogens / Medroxyprogesterone Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1324)" • "Medication, Order: Cyclobenzaprine Hydrochloride" using "Cyclobenzaprine Hydrochloride Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1372)" • "Medication, Order: Desiccated Thyroid" using "Desiccated Thyroid Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1354)" • "Medication, Order: Dexbrompheniramine" using "Dexbrompheniramine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1375)" • "Medication, Order: Dexbrompheniramine / Dextromethorphan / Phenylephrine" using "Dexbrompheniramine / Dextromethorphan / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1426)" • "Medication, Order: Dexbrompheniramine / Dextromethorphan / Pseudoephedrine" using "Dexbrompheniramine / Dextromethorphan / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1438)" • "Medication, Order: Dexbrompheniramine / Phenylephrine" using "Dexbrompheniramine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1384)" • "Medication, Order: Dexbrompheniramine / Pseudoephedrine" using "Dexbrompheniramine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1430)" • "Medication, Order: Dexbrompheniramine Maleate / Pseudoephedrine Hydrochloride" using "Dexbrompheniramine Maleate / Pseudoephedrine Hydrochloride Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1429)" • "Medication, Order: Dexchlorpheniramine" using "Dexchlorpheniramine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1391)" • "Medication, Order: Dexchlorpheniramine / Dextromethorphan / Pseudoephedrine" using "Dexchlorpheniramine / Dextromethorphan / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1300)" • "Medication, Order: Dexchlorpheniramine / Phenylephrine" using "Dexchlorpheniramine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1403)" • "Medication, Order: Dexchlorpheniramine / Pseudoephedrine" using "Dexchlorpheniramine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1425)" • "Medication, Order: Dextromethorphan / Diphenhydramine / Phenylephrine" using "Dextromethorphan / Diphenhydramine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1397)" • "Medication, Order: Dextromethorphan / Doxylamine" using "Dextromethorphan / Doxylamine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1452)" • "Medication, Order: Dextromethorphan / Doxylamine / Pseudoephedrine" using "Dextromethorphan / Doxylamine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1444)" • "Medication, Order: Dextromethorphan / Promethazine" using "Dextromethorphan / Promethazine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1314)" • "Medication, Order: Dienogest / Estradiol Multiphasic" using "Dienogest / Estradiol Multiphasic Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1398)" • "Medication, Order: Diphenhydramine / Ibuprofen" using "Diphenhydramine / Ibuprofen Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1293)" • "Medication, Order: Diphenhydramine / Magnesium Salicylate" using "Diphenhydramine / Magnesium Salicylate Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1395)" • "Medication, Order: Diphenhydramine / Naproxen" using "Diphenhydramine / Naproxen Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1406)" • "Medication, Order: Diphenhydramine / Phenylephrine" using "Diphenhydramine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1307)" • "Medication, Order: Diphenhydramine / Pseudoephedrine" using "Diphenhydramine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1392)" • "Medication, Order: Diphenhydramine Hydrochloride" using "Diphenhydramine Hydrochloride Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1371)" • "Medication, Order: Dipyridamole" using "Dipyridamole Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1349)" • "Medication, Order: Disopyramide" using "Disopyramide Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1311)" • "Medication, Order: Doxylamine" using "Doxylamine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1290)" • "Medication, Order: Doxylamine / Phenylephrine" using "Doxylamine / Phenylephrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1387)" • "Medication, Order: Doxylamine / Pseudoephedrine" using "Doxylamine / Pseudoephedrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1448)" • "Medication, Order: Doxylamine / Pyridoxine" using "Doxylamine / Pyridoxine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1379)" • "Medication, Order: Drospirenone / Estradiol" using "Drospirenone / Estradiol Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1410)" • "Medication, Order: Ergoloid Mesylates" using "Ergoloid Mesylates Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1288)" • "Medication, Order: Esterified Estrogens" using "Esterified Estrogens Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1419)" • "Medication, Order: Esterified Estrogens / Methyltestosterone" using "Esterified Estrogens / Methyltestosterone Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1320)" • "Medication, Order: Estradiol" using "Estradiol Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1365)" • "Medication, Order: Estradiol / Levonorgestrel" using "Estradiol / Levonorgestrel Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1483)" • "Medication, Order: Estradiol / Norethindrone" using "Estradiol / Norethindrone Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1323)" • "Medication, Order: Estradiol / Norgestimate Biphasic" using "Estradiol / Norgestimate Biphasic Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1396)" • "Medication, Order: Estropipate" using "Estropipate Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1319)" • "Medication, Order: Glyburide" using "Glyburide Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1368)" • "Medication, Order: Glyburide / Metformin" using "Glyburide / Metformin Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1360)" • "Medication, Order: Guanfacine" using "Guanfacine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1341)" • "Medication, Order: High Risk Medications for the Elderly" using "High Risk Medications for the Elderly Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1253)" • "Medication, Order: High-Risk Medications With Days Supply Criteria" using "High-Risk Medications With Days Supply Criteria Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1254)" • "Medication, Order: Hydrochlorothiazide / Methyldopa" using "Hydrochlorothiazide / Methyldopa Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1414)" • "Medication, Order: Hydroxyzine" using "Hydroxyzine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1374)" • "Medication, Order: Imipramine" using "Imipramine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1359)" • "Medication, Order: Indomethacin" using "Indomethacin Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1366)" • "Medication, Order: Isoxsuprine" using "Isoxsuprine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1422)" • "Medication, Order: Ketorolac Tromethamine" using "Ketorolac Tromethamine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1364)" • "Medication, Order: Megestrol" using "Megestrol Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1342)" • "Medication, Order: Meperidine" using "Meperidine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1351)" • "Medication, Order: Meperidine / Promethazine" using "Meperidine / Promethazine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1393)" • "Medication, Order: Mephobarbital" using "Mephobarbital Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1413)" • "Medication, Order: Meprobamate" using "Meprobamate Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1284)" • "Medication, Order: Metaxalone" using "Metaxalone Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1358)" • "Medication, Order: Methocarbamol" using "Methocarbamol Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1370)" • "Medication, Order: Methyldopa" using "Methyldopa Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1331)" • "Medication, Order: Naloxone / Pentazocine" using "Naloxone / Pentazocine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1346)" • "Medication, Order: Nifedipine" using "Nifedipine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1353)" • "Medication, Order: Nonbenzodiazepine hypnotics" using "Nonbenzodiazepine hypnotics Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1480)" • "Medication, Order: Orphenadrine" using "Orphenadrine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1356)" • "Medication, Order: Pentazocine" using "Pentazocine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1407)" • "Medication, Order: Pentobarbital" using "Pentobarbital Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1401)" • "Medication, Order: Phenobarbital" using "Phenobarbital Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1348)" • "Medication, Order: Phenylephrine / Promethazine" using "Phenylephrine / Promethazine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1294)" • "Medication, Order: Phenylephrine / Triprolidine" using "Phenylephrine / Triprolidine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1385)" • "Medication, Order: Promethazine Hydrochloride" using "Promethazine Hydrochloride Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1367)" • "Medication, Order: Pseudoephedrine / Triprolidine" using "Pseudoephedrine / Triprolidine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1345)" • "Medication, Order: Secobarbital" using "Secobarbital Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1298)" • "Medication, Order: Thioridazine" using "Thioridazine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1344)" • "Medication, Order: Ticlopidine" using "Ticlopidine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1304)" • "Medication, Order: Trihexyphenidyl" using "Trihexyphenidyl Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1334)" • "Medication, Order: Trimethobenzamide" using "Trimethobenzamide Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1335)" • "Medication, Order: Trimipramine" using "Trimipramine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1285)" • "Medication, Order: Triprolidine" using "Triprolidine Grouping Value Set (2.16.840.1.113883.3.464.1003.196.12.1408)" • Attribute: "Discharge status: Discharged to Health Care Facility for Hospice Care" using "Discharged to Health Care Facility for Hospice Care SNOMEDCT Value Set (2.16.840.1.113883.3.117.1.7.1.207)" • Attribute: "Discharge status: Discharged to Home for Hospice Care" using "Discharged to Home for Hospice Care SNOMEDCT Value Set (2.16.840.1.113883.3.117.1.7.1.209)"

Supplemental Data Elements

• "Patient Characteristic Ethnicity: Ethnicity" using "Ethnicity CDCREC Value Set (2.16.840.1.114222.4.11.837)" • "Patient Characteristic Payer: Payer" using "Payer SOP Value Set (2.16.840.1.114222.4.11.3591)" • "Patient Characteristic Race: Race" using "Race CDCREC Value Set (2.16.840.1.114222.4.11.836)" • "Patient Characteristic Sex: ONC Administrative Sex" using "ONC Administrative Sex AdministrativeGender Value Set (2.16.840.1.113762.1.4.1)"

Risk Adjustment Variables

• None

Measure Set None