Iowa Center for Education and Anticholinergic Meds (Continued) Anticholinergic Meds (Continued) Research on Therapeutics The University of Iowa Motion Sickness, Dizziness, Nausea Ulcer & Acid Reflux Dimenhydrinate (Dramamine) Cimetidine (Tagamet) Meclizine (Dramamine II, Ranitidine (Zantac) Antivert) Anticholinergic Prochlorperazine (Compazine) Gastrointestinal Muscle Relaxers Promethazine (Phenergan) Scopolamine (Transderm Scop, Clidinium (Librax) Medications in Scopace, Donnatal) Dicyclomine (Bentyl) Hyoscyamine (Levsin, Levbid, Symax, HyoMax) Tricyclic Antidepressants Older Adults Amitripyline (Elavil) Desipramine (Norpramin, Eye Drops Pertofrane) Atropine (Atropisol) Doxepin (Sinequan, Silenor) Pheneramine (Opcon-A) What are they used for? Imipramine (Tofranil) Scopolamine (Isopto Hyoscine) Nortriptyline (Pamelor) Protriptyline (Vivactil) What side effects can they cause? Anxiety For more information on Hydroxyzine (Atarax) Who is at risk? medication use and safety in Seizures, Mood Swings older adults, visit: Carbamazepine (Tegretol) www.IowaCERT.org
Muscle Spasms, Muscle Pain
Cyclobenzaprine (Flexeril, Fexmid, Amrix) Orphenadrine (Norflex, Flexon, Mephenamin) This work was supported by an Agency for Phenyltoloxamine (Doans, Vicks Healthcare Research and Quality (AHRQ) Centers Percogesic, Momentum Extra) for Education and Research on Therapeutics cooperative agreement #5 U18 HSO16094
Q: What is an anticholinergic? Q: Who is at risk? Anticholinergic Medicines
A: “Anticholinergic” is a term A: Older adults, especially (grouped by reason for use)
for a drug that reduces those with dementia, are Allergies, Cold & Cough acetylcholine activity. more likely to have confusion Azelastine nasal spray (Astelin, Acetylcholine is a and sedation side effects. Astepro) Other side effects are also neurotransmitter that plays Brompheniramine (Bromfed, an important role in the more common in older adults. Dimetapp) nervous system. Chlorpheniramine (Clor- Q: What should I do if I am Trimeton) Q: What side effects can taking an anticholinergic? Clemastine or Meclastin (Tavist) they have? Dexbrompheniramine (Drixoral) A: Ask your doctor or Dexchlorpheniramine A: Anticholinergics can cause pharmacist whether there is (Polaramine) Diphenhydramine (Benadryl) Confusion a safer drug you could be taking instead. Tell your Hydroxyzine (Atarax, Vistaril) Sedation (sleepiness) doctor or pharmacist if you Olopatadine nasal spray Constipation (Pantanase) think you are experiencing
Difficulty urinating side effects. Blurred vision Bladder Problems Dry mouth Q: Which drugs have Darifenacin (Enablex) High temperature anticholinergic effects? Flavoxate (Urispas) Oxybutynin (Ditropan, Gelnique) High heart rate A: Drugs with anticholinergic Solifenacin (Vesicare) Loss of balance and falls effects are commonly used Tolterodine (Detrol) to treat allergies, colds, Trospium (Sanctura) bladder problems, stomach or intestinal problems, and Insomnia & Sleep Problems other ailments. Some Diphenhydramine (Tylenol PM, common anticholinergics are generic PM pain relievers) listed on the next page and Doxylamine (Unisom, generic other side of this brochure. nighttime sleep aids)