DOCSLIB.ORG

Mixing Alcohol with Other Drugs

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Mixing Alcohol with Other Drugs Mixing Alcohol With Other Drugs Mixing Alcohol with other drugs--prescription and non prescription--can have complicated, and at times dangerous interactions. Alcohol is a Central Nervous System Depressant literally hundreds of medications can lead to alcohol (also called ethanol) interactions, it is important to review your medicines with your pharmacist or other health care provider to check for clinically significant drug-alcohol reactions. Even though some research suggests that moderate alcohol consumption is heart healthy, certain medications and alcohol have the capacity to interfere with your successful treatment The danger is real. Mixing alcohol with certain medications can cause nausea and vomiting, headaches, drowsiness, fainting, or loss of coordination. It also can put you at risk for internal bleeding, heart problems, and difficulties in breathing. In addition to these dangers, alcohol can make a medication less effective or even useless, or it may make the medication harmful or toxic to your body. Some medicines that you might never have suspected can react with alcohol, including many medications which can be purchased “over- the-counter”—that is, without a prescription. Even some herbal remedies can have harmful effects when combined with alcoho Check with You Doctor and/or Pharmacist. Medications typically are safe and effective when used appropriately. Your pharmacist or other health care provider can help you determine which medications interact harmfully with alcohol. Medication Some possible Medication (Generic Symptom/Disorders (Brand reactions with name) name) alcohol Allergies/Colds/Flu • Alavert® Loratadine Drowsiness, dizziness; increased risk for overdose • Atarax® Hydroxyzine • Benadryl® Diphenhydramine • Clarinex® Desloratadine • Claritin®, Loratadine Claritin-D® • Dimetapp® Brompheniramine Cold &Allergy • Sudafed® Chlorpheniramine Sinus & Allergy • Triaminic® Chlorpheniramine Cold & Allergy • Tylenol® Chlorpheniramine Allergy Sinus • Tylenol® Cold Chlorpheniramine & Flu • Zyrtec® Cetirizine Angina (chest pain), • Isordil® Isosorbide Rapid heartbeat, coronary heart disease Nitroglycerin sudden changes in blood pressure, dizziness, fainting Anxiety and epilepsy • Ativan® Lorazepam Drowsiness, dizziness; increased risk for overdose; • BuSpar® Buspirone Medication Some possible Medication (Generic Symptom/Disorders (Brand reactions with name) name) alcohol • Klonopin® Clonazepam slowed or difficulty breathing; impaired motor control; • Librium® Chlordiazepoxide unusual behavior; memory problems • Paxil® Paroxetine • Valium® Diazepam • Xanax® Alprazolam • Herbal Liver damage, preparations drowsiness (Kava Kava) Arthritis • Celebrex® Celecoxib Ulcers, stomach bleeding, liver damage • Naprosyn® Naproxen • Voltaren® Diclofenac Attention and • Adderall® Amphetamine/dextro- Dizziness, concentration amphetamine drowsiness, impaired (Attention concentration deficit/hyperactivity (methylphenidate, disorder) • Concerta®, Methylphenidate dexmethylphenidate); Ritalin® possible increased risk for heart problems • Dexedrine® Dextroamphetamine (amphetamine, dextroamphetamine, • Focalin® Dexmethylphenidate lisdexamfetamine); liver damage (atomoxetine) • Strattera® Atomoxetine • Vyvanse® Lisdexamfetamine Blood clots • Coumadin® Warfarin Occasional drinking may lead to internal bleeding; heavier drinking also may cause bleeding or may have the opposite effect, resulting in possible blood clots, strokes, or heart attacks Cough • Delsym®, Dextromethorpan Drowsiness, Robitussin dizziness; increased Cough® risk for overdose • Robitussin A– Guaifenesin + codeine C® Depression • Abilify® Aripriprazone Drowsiness, dizziness; increased risk for overdose; • Anafranil® Clomipramine increased feelings of depression or hopelessness (all • Celexa® Citalopram Medication Some possible Medication (Generic Symptom/Disorders (Brand reactions with name) name) alcohol • Clozaril® Clozapine medications); impaired motor control (quetiapine, • Cymbalta® Duloxetine mirtazapine); increased alcohol effect (bupropion); • Desyrel® Trazodone liver damage (duloxetine) • Effexor® Venlafaxine • Elavil® Amitriptyline Monoamine oxidase inhibitors (MAOIs), such as • Geodon® Ziprasidone tranylcypromine and phenelzine, when combined with • Invega® Paliperidone alcohol, may result in serious heart-related • Lexapro® Escitalopram side effects. Risk for dangerously high blood pressure is • Luvox® Fluvoxamine increased when MAOIs are mixed with tyramine, a • Nardil® Phenelzine byproduct found in beer and red wine • Norpramin® Desipramine • Pamate® Tranylcypromine • Paxil® Paroxetine • Pristiq® Desevenlafaxine • Prozac® Fluoxetine • Remeron® Mirtazapine • Risperdal® Risperidone • Seroquel® Quetiapine • Serzone® Nefazodone • Symbyax® Fluoxetine/Olanzapine • Wellbutrin® Bupropion • Zoloft® Sertraline • Zyprexa® Olanzapine • Herbal preparations (St. John’s Wort) Diabetes • Diabinese® Chlorpropamide Abnormally low blood sugar levels, flushing reaction • Glucotrol® Glipizide Medication Some possible Medication (Generic Symptom/Disorders (Brand reactions with name) name) alcohol • Glucophage® Metformin (nausea, vomiting, headache, rapid heartbeat, sudden • Glynase®, Glyburide changes in blood DiaBeta®, pressure); symptoms Micronase® of nausea and weakness may occur (metformin) • Orinase® Tolbutamide • Tolinase® Tolazamide Enlarged prostate • Cardura® Doxazosin Dizziness, light headedness, fainting • Flomax® Tamsulosin • Hytrin® Terazosin • Minipress® Prazosin Heartburn, • Axid® Nizatidine Rapid heartbeat; indigestion, sour increased alcohol stomach effect; sudden • Reglan® Metoclopramide changes in blood pressure (metoclopramide) • Tagamet® Cimetidine • Zantac® Ranitidine High blood pressure • Accupril® Quinapril Dizziness, fainting, drowsiness; heart problems such as • Calan® Verapamil changes in the heart’s regular heartbeat (arrhythmia) • Capozide® Hydrochlorothiazide • Cardura® Doxazosin • Catapres® Clonidine • Cozaar® Losartan • Hytrin® Terazosin • Lopressor® Hydrochlorothiazide HCT • Lotensin® Benzapril • Minipress® Prazosin • Norvasc® Amlodipine mesylate • Prinivil®, Lisinopril Zestril® • Vaseretic® Enalapril High cholesterol • Advicor® Lovastatin + Niacin Medication Some possible Medication (Generic Symptom/Disorders (Brand reactions with name) name) alcohol • Altocor® Lovastatin • Crestor® Rosuvastatin • Lipitor® Atorvastatin • Mevacor® Lovastatin Liver damage (all medications); increased flushing • Niaspan® Niacin and itching (niacin), increased stomach • Pravachol® Pravastatin bleeding (pravastatin + aspirin) • Pravigard™ Pravastatin + Aspirin • Vytorin™ Ezetimibe + Simvastatin • Zocor® Simvastatin Infections • Acrodantin® Nitrofurantoin Fast heartbeat, sudden changes in blood pressure; • Flagyl® Metronidazole stomach pain, upset stomach, vomiting, headache, or flushing • Grisactin® Griseofulvin or redness of the face; liver damage • Nizoral® Ketoconazole (isoniazid, ketoconazole) • Nydrazid® Isoniazid • Seromycin® Cycloserine • Tindamax® Tinidazole • Zithromax® Azithromycin Mood stabilizers • Depakene®, Valproic acid Drowsiness, Depakote® dizziness; tremors; increased risk for side effects, such as • Eskalith®, Lithium restlessness, impaired Eskalith®CR, motor control; loss of Lithobid appetite; stomach upset; irregular bowel movement; joint or muscle pain; depression; liver damage (valproic acid) Muscle pain • Flexeril® Cyclobenzaprine Drowsiness, dizziness; increased risk of seizures; • Soma® Carisoprodol increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems Medication Some possible Medication (Generic Symptom/Disorders (Brand reactions with name) name) alcohol Nausea, motion • Antivert® Meclizine Drowsiness, sickness dizziness; increased risk for overdose • Dramamine® Dimenhydrinate • Phenergan® Promethazine Pain (such as muscle • Advil® Ibuprofen Stomach upset, ache, minor arthritis bleeding and ulcers; pain), fever, liver damage inflammation • Aleve® Naproxen (acetaminophen); rapid heartbeat • Excedrin® Aspirin, Acetaminophen • Motrin® Ibuprofen • Tylenol® Acetaminophen Seizures • Dilantin® Phenytoin Drowsiness, dizziness; increased risk of seizures • Horizant®, Gabapentin (levetiracetam, Neurontin® phenytoin); unusual behavior and changes in mental health • Keppra® Levetiracetam (such as thoughts of suicide) (topiramate) • Klonopin® Clonazepam Phenobarbital • Lamictal® Lamotrigine • Lyrica® Pregabalin • Tegretol® Carbamazepine • Topamax® Topiramate • Trileptal® Oxcarbazepine Barbiturates Severe pain from • Darvocet–N® Propoxyphene Drowsiness, injury, postsurgical dizziness; increased care, oral surgery, risk for overdose; migraines • Demerol® Merepidine slowed or difficulty breathing; impaired motor control; • Fiorinal® with Butalbital + codeine unusual behavior; codeine memory problems • Percocet® Oxycodone • Vicodin® Hydrocodone Sleep problems • Ambien® Zolpidem Drowsiness, sleepiness, dizziness; slowed or difficulty • Lunesta™ Eszopiclone Medication Some possible Medication (Generic Symptom/Disorders (Brand reactions with name) name) alcohol • Prosom™ Estazolam breathing; impaired motor control; unusual behavior; • Restoril® Temazepam memory problems • Sominex® Diphenhydramine • Unisom® Doxylamine • Herbal Increased drowsiness preparations (chamomile, valerian, lavender) Commonly Used Medicines (Both Prescription and Over-the-Counter) That Interact With Alcohol Additional Resources MedlinePlus A service of the U.S. National Library of Medicine and the National Institutes
Load more

Recommended publications
  • Insomnia and Anxiety in Older People Sleeping Pills Are Usually Not the Best Solution
    ® Insomnia and anxiety in older people Sleeping pills are usually not the best solution lmost one-third of older people in the people who take one of United States take sleeping pills. These these medicines sleep medicines are also sometimes called only a little longer and A“sedative-hypnotics” or “tranquilizers.” They better than those who affect the brain and spinal cord. don’t take a medicine. Doctors prescribe some of these medicines Sleeping pills can for sleep problems. Some of these medicines have serious side effects. also can be used to treat other conditions, such All sedative-hypnotic medicines have special as anxiety or alcohol withdrawal. Sometimes, risks for older adults. Seniors are likely to be doctors also prescribe certain anti-depressants more sensitive to the medicines’ effects than for sleep, even though that’s not what they’re younger adults. And these medicines may designed to treat. stay in older people’s bodies longer. These Most older adults should first try to treat their medicines can cause confusion and memory insomnia without medicines. According to the problems that: American Geriatrics Society, there are safer and • Increase the risk of falls and hip fractures. better ways to improve sleep or reduce anxiety. These are common causes of hospital stays Here’s why: and death in older people. Sleeping pills may not help much. • Increase the risk of car accidents. Many ads say that sleeping pills help people get a full, restful night’s sleep. But studies show that this is not exactly true in real life. On average, The new “Z” medicines also have risks.
    [Show full text]
  • Drug & Alcohol Testing Program
    Pottawattmie County Drug & Alcohol Testing Program Appendix A Table of Contents POLICY STATEMENT ...................................................................................................................................... 3 SCOPE ............................................................................................................................................................ 4 EDUCATION AND TRAINING .......................................................................................................................... 4 DESIGNATED EMPLOYER REPRESENTATIVE (DER): ....................................................................................... 5 DUTY TO COOPERATE ................................................................................................................................... 5 EMPLOYEE ADMISSION OF ALCOHOL AND CONTROLLED SUBSTANCE USE: (49 CFR Part 382.121) ... 6 PROHIBITED DRUGS AND ILLEGALLY USED CONTROLLED SUBSTANCES: ..................................................... 7 PROHIBITED BEHAVIOR AND CONDUCT: ...................................................................................................... 8 DRUG & ALCOHOL TESTING REQUIREMENTS (49 CFR, Part 40 & 382) ............................................... 10 DRUG & ALCOHOL TESTING CIRCUMSTANCES (49 CFR Part 40 & 382) .............................................. 12 A. Pre-Employment Testing: .................................................................................................... 12 B. Reasonable Suspicion Testing: .........................................................................................
    [Show full text]
  • 2015-16 59. On-Line Learning Bipolar Medications
    Pharmacology/Therapeutics II Block II Handouts – 2015‐16 59. On‐Line learning Bipolar Medications ‐ Schilling 60. On‐Line Learning Anti‐Depressants ‐ Schilling 61. On‐Line Learning Sedative Hypnotics ‐ Battaglia 62. On‐Line Learning Treatment of Insomnia ‐ Battaglia 63. On‐Line Learning AntiPsychotics ‐ Schilling 64. On‐Line Only Drugs of Abuse, tolerance & Dependence – Bakowska 65. Active Learning Session: Mood Disorders & Treatment – Schilling 66. Active Learning Session – Anxiety Disorders – Schilling 67. Active Learning Session – Psychotic Illness & Treatment – Schilling 68. Drugs to Treat Rheumatoid Arthritis & Gout ‐ Clipstone Pharmacology & Therapeutics Bipolar Medications February 15, 2016 David Schilling, M.D. Bipolar Disorder Medications Goals & Objectives: Describe the pharmacologic profiles of major drugs/drug classes used in the treatment of bipolar disorder. These drugs include: Lithium, Divalproex (Depakote), Carbamazepine (Tegretol), Lamotrigine (Lamictal) 1. List the major drugs/drug classes used in the treatment of bipolar disorder 2. Describe the mechanism of action of each of the major drugs/drug classes used in the treatment of bipolar disorder 3. Describe the principle pharmacokinetic properties of the major drugs used to treat bipolar disorder. This includes: half-life & time to steady state, trough levels, metabolic auto-induction, P450 system induction, therapeutic index 4. Describe the pharmacodynamics (common adverse effects) of the major drugs used to treat bipolar disorder. 5. Describe the pharmacodynamics (serious adverse effects) of the major drugs used to treat bipolar disorder. This includes: lithium toxicity, agranulocytosis, aplastic anemia, hepatic failure, exfoliative dermatitis, pancreatitis, Steven’s Johnson syndrome 6. Identify the laboratory tests that may be used to monitor for common and serious major adverse effects of the major drugs used to treat bipolar disorder.
    [Show full text]
  • Optum Essential Health Benefits Enhanced Formulary PDL January
    PENICILLINS ketorolac tromethamineQL GENERIC mefenamic acid amoxicillin/clavulanate potassium nabumetone amoxicillin/clavulanate potassium ER naproxen January 2016 ampicillin naproxen sodium ampicillin sodium naproxen sodium CR ESSENTIAL HEALTH BENEFITS ampicillin-sulbactam naproxen sodium ER ENHANCED PREFERRED DRUG LIST nafcillin sodium naproxen DR The Optum Preferred Drug List is a guide identifying oxacillin sodium oxaprozin preferred brand-name medicines within select penicillin G potassium piroxicam therapeutic categories. The Preferred Drug List may piperacillin sodium/ tazobactam sulindac not include all drugs covered by your prescription sodium tolmetin sodium drug benefit. Generic medicines are available within many of the therapeutic categories listed, in addition piperacillin sodium/tazobactam Fenoprofen Calcium sodium to categories not listed, and should be considered Meclofenamate Sodium piperacillin/tazobactam as the first line of prescribing. Tolmetin Sodium Amoxicillin/Clavulanate Potassium LOW COST GENERIC PREFERRED For benefit coverage or restrictions please check indomethacin your benefit plan document(s). This listing is revised Augmentin meloxicam periodically as new drugs and new prescribing LOW COST GENERIC naproxen kit information becomes available. It is recommended amoxicillin that you bring this list of medications when you or a dicloxacillin sodium CARDIOVASCULAR covered family member sees a physician or other penicillin v potassium ACE-INHIBITORS healthcare provider. GENERIC QUINOLONES captopril ANTI-INFECTIVES
    [Show full text]
  • Drug and Alcohol Abuse Prevention Handbook FOREWARD
    Drug and Alcohol Abuse Prevention Handbook FOREWARD Grayson College recognizes that the illicit use of drugs and/or the abuse of alcohol are a persistent health problem of major proportion affecting our society physically, mentally, and socially. Illicit drug use and /or alcohol abuse can adversely affect an individual’s personal life, safety, health, and mental and physical performance. It is the intent of GC to provide employees and students pertinent information related to illicit drug use and/or alcohol abuse in an effort to prevent such harm. GC is committed to promoting and maintaining a work and academic environment that is free from illegal alcohol and drug use and abuse, in accordance with all federal, state, and local laws. Students, employees, and visitors are prohibited from possessing, consuming, manufacturing, dispensing, or being under the influence of alcohol/illegal drugs or engaging in improper self- medication while on college property or college business. Any member of the college community who violates this policy is subject to both prosecution and punishment under federal, state, and local laws to disciplinary proceedings by the college. This alcohol/drug policy is not designed to punish people for seeking rehabilitation. All information about those individuals who voluntarily avail themselves of drug or alcohol counseling or rehabilitation will not be used as a basis for disciplinary action or be used against an individual in any way. College employees and students who violate the alcohol/drug policy shall be informed about and referred to services to assist them in determining whether they are abusing drugs and alcohol or are chemically dependent.
    [Show full text]
  • For Personal Use Only
    SedatiWITH ANTIi ® Dowden Health Media CopyrightFor personal use only Initiate the antipsychotic at a reasonable, not overly high dose, then use a nonantipsychotic to help control insomnia, anxiety, and agitation For mass reproduction, content licensing and permissions contact Dowden Health Media. pSYCHIATRY i PSYCHOTICSon edation is a frequent side effect of antipsychot- ics, especially at relatively high doses. Antipsy- S chotics’ sedative effects can reduce agitation in acute psychosis and promote sleep in insomnia, but Manage, don’t long-term sedation may: • interfere with schizophrenia patients’ efforts to go accept adverse to work or school or engage in normal socialization • prevent improvement from psychosocial training, psychiatric rehabilitation, and other treatments. ‘calming’ eff ect This article discusses how to manage acute psycho- sis without oversedation and ways to address persistent sedation and chronic insomnia with less-sedating anti- Del D. Miller, PharmD, MD Professor of psychiatry psychotics or adjunctive medications. University of Iowa Carver College of Medicine Iowa City Neurobiology or psychopharmacology? Many patients experience only mild, transient som- nolence at the beginning of antipsychotic treatment, and most develop some tolerance to the sedating ef- fects with continued administration. Others may have persistent daytime sedation that interferes with nor- mal functioning. Sedation is especially common in elderly patients re- ceiving antipsychotics. Compared with younger patients, older patients receiving
    [Show full text]
  • The Case of Ketamine Allergy
    CASE REPORT The Case of Ketamine Allergy William Bylund, MD Department of Emergency Medicine, Naval Medical Center Portsmouth, Portsmouth, Virginia Liam Delahanty, MD Maxwell Cooper, MD Section Editor: Rick A. McPheeters, DO Submission history: Submitted April 3, 2017; Revision received June 29, 2017; Accepted July 11, 2017 Electronically published October 3, 2017 Full text available through open access at http://escholarship.org/uc/uciem_cpcem DOI: 10.5811/cpcem.2017.7.34405 Ketamine is often used for pediatric procedural sedation due to low rates of complications, with allergic reactions being rare. Immediately following intramuscular (IM) ketamine administration, a three-year-old female rapidly developed facial edema and diffuse urticarial rash, with associated wheezing and oxygen desaturation. Symptoms resolved following treatment with epinephrine, dexamethasone and diphenhydramine. This case presents a clinical reaction to ketamine consistent with anaphylaxis due to histamine release, but it is uncertain whether this was immunoglobulin E mediated. This is the only case reported to date of allergic reaction to IM ketamine, without co- administration of other agents. [Clin Pract Cases Emerg Med.2017;1(4):323–325.] INTRODUCTION cardiac monitor, end tidal CO2 (ETCO2) and pulse oximetry Ketamine is a common medication, used in isolation as well (POx), in addition to being placed on two liters nasal cannula as with other agents, for pediatric sedation in the emergency (NC). No intravenous (IV) access was obtained prior to sedation. department (ED). It is often turned to because of its efficacy, ease Seventy milligrams (4.4mg/kg) of ketamine was administered IM of use, and favorable safety profile. Common side effects of into the right thigh.
    [Show full text]
  • Clomipramine | Memorial Sloan Kettering Cancer Center
    PATIENT & CAREGIVER EDUCATION Clomipramine This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Brand Names: US Anafranil Brand Names: Canada Anafranil; MED ClomiPRAMINE; TARO-Clomipramine Warning Drugs like this one have raised the chance of suicidal thoughts or actions in children and young adults. The risk may be greater in people who have had these thoughts or actions in the past. All people who take this drug need to be watched closely. Call the doctor right away if signs like low mood (depression), nervousness, restlessness, grouchiness, panic attacks, or changes in mood or actions are new or worse. Call the doctor right away if any thoughts or actions of suicide occur. This drug is not approved for use in all children. Talk with the doctor to be sure that this drug is right for your child. What is this drug used for? It is used to treat obsessive-compulsive problems. It may be given to you for other reasons. Talk with the doctor. Clomipramine 1/8 What do I need to tell my doctor BEFORE I take this drug? If you have an allergy to clomipramine or any other part of this drug. If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. If you have had a recent heart attack. If you are taking any of these drugs: Linezolid or methylene blue.
    [Show full text]
  • Atomoxetine: a New Pharmacotherapeutic Approach in the Management of Attention Deficit/Hyperactivity Disorder
    i26 Arch Dis Child: first published as 10.1136/adc.2004.059386 on 21 January 2005. Downloaded from Atomoxetine: a new pharmacotherapeutic approach in the management of attention deficit/hyperactivity disorder J Barton ............................................................................................................................... Arch Dis Child 2005;90(Suppl I):i26–i29. doi: 10.1136/adc.2004.059386 Atomoxetine is a novel, non-stimulant, highly selective lifespan including a potential requirement for lifelong treatment.4 Because of the limitations of noradrenaline reuptake inhibitor that has been studied for existing treatments and the paradigm shift in use in the treatment of attention deficit/hyperactivity thinking about the management of ADHD, there disorder (ADHD). Data from clinical trials show it to be well is an interest in the development of new pharmacological treatments. tolerated and effective in the treatment of ADHD in children, adolescents, and adults. Improvements were seen ATOMOXETINE HYDROCHLORIDE: A not only in core symptoms of ADHD, but also in broader NOVEL TREATMENT FOR ADHD social and family functioning and self esteem. Once-daily Atomoxetine is the first non-stimulant to be approved for the treatment of ADHD and the first dosing of atomoxetine has been shown to be effective in drug to be licensed for the treatment of ADHD in providing continuous symptom relief. Atomoxetine does adults.5 Atomoxetine was licensed in the US in not appear to have abuse potential and is associated with November 2002 and in the UK in May 2004. At the time of writing, it is under consideration for a benign side effect profile. The development of licensing by the regulatory authorities in a atomoxetine thus represents an important advance in the number of other countries.
    [Show full text]
  • Potentially Harmful Drugs in the Elderly: Beers List
    −This Clinical Resource gives subscribers additional insight related to the Recommendations published in− March 2019 ~ Resource #350301 Potentially Harmful Drugs in the Elderly: Beers List In 1991, Dr. Mark Beers and colleagues published a methods paper describing the development of a consensus list of medicines considered to be inappropriate for long-term care facility residents.12 The “Beers list” is now in its sixth permutation.1 It is intended for use by clinicians in outpatient as well as inpatient settings (but not hospice or palliative care) to improve the care of patients 65 years of age and older.1 It includes medications that should generally be avoided in all elderly, used with caution, or used with caution or avoided in certain elderly.1 There is also a list of potentially harmful drug-drug interactions in seniors, as well as a list of medications that may need to be avoided or have their dosage reduced based on renal function.1 This information is not comprehensive; medications and interactions were chosen for inclusion based on potential harm in relation to benefit in the elderly, and availability of alternatives with a more favorable risk/benefit ratio.1 The criteria no longer address drugs to avoid in patients with seizures or insomnia because these concerns are not unique to the elderly.1 Another notable deletion is H2 blockers as a concern in dementia; evidence of cognitive impairment is weak, and long-term PPIs pose risks.1 Glimepiride has been added as a drug to avoid. Some drugs have been added with cautions (dextromethorphan/quinidine, trimethoprim/sulfamethoxazole), and some have had cautions added (rivaroxaban, tramadol, SNRIs).
    [Show full text]
  • Medication Choice Diabetes
    Weight Change Low Blood Sugar Blood Sugar Considerations (Hypoglycemia) Blood(A1c Reduction) Sugar Weight Change Low Blood Sugar (A1c Reduction) Considerations (Hypoglycemia) Metformin Metformin Metformin 1 – 2% Metformin In the rst few weeks after starting Metformin, patients may have some nausea, indigestion or diarrhea. None No Severe Risk Minor = 0 – 1% Insulin There are no other side effects associated with Insulin. Insulin Insulin Insulin Unlimited % Pioglitazone 4 to 6 lb. gain Over time, 10 in 100 people may have fluid retention Severe = 1 – 3% Minor = 30 – 40% (edema) while taking the drug. For some it may be as little as ankle swelling. For others, fluid may build up Pioglitazone 1% in the lungs making it difficult to breathe. This may Pioglitazone Pioglitazone resolve after you stop taking the drug. 10 in 100 people at risk of bone fractures who use this drug will have More than 2 to 6 lb. gain a bone fracture in the next 10 years. There appears to No Severe Risk Minor = 1 – 2% be a slight increase in the risk of bladder cancer with Liraglutide/ 0.5 – 1% this drug. Liraglutide/Exenatide Liraglutide/Exenatide Exenatide Liraglutide/Exenatide Some patients may have nausea or diarrhea. In some 3 to 6 lb. loss cases, the nausea may be severe enough that a patient No Severe Risk Minor = 0 – 1% has to stop taking the drug. There are reports of pain in the abdomen that may be caused by inammation Sulfonylureas Sulfonylureas Sulfonylureas 1 – 2% of the pancreas with these agents. Glipizide, Glimepiride, Glyburide Glipizide, Glimepiride, Glyburide Glipizide, Glimepiride, Glyburide Sulfonylureas 2 to 3 lb.
    [Show full text]
  • Kiwiherb Valerian Oral Liquid Valerian Root Extract
    PATIENT INFORMATION LEAFLET: stress and to aid sleep, exclusively based on long standing use. 2. Before you take this product DO NOT TAKE this product if you are: • Allergic to Valerian or any other ingredients in this product (see section 6) • Under 18 years of age • Pregnant or breast feeding • Taking medicines known to interact with alcohol (e.g. metronidazole) • Already taking a medicine for sleep or Kiwiherb Valerian Oral Liquid anxiety Valerian Root Extract Taking other medicines Tell your healthcare professional, e.g. a doctor or pharmacist, if you are taking any other medicines Read all of this leaflet carefully because it contains including herbal medicines or medicines that did important information for you. not require a prescription. This medicine is available without prescription. Driving and using machines However you still need to use Kiwiherb Valerian carefully to get the best results from it. This product may cause drowsiness. If affected, do not drive or operate machinery Keep this leaflet. You may want to read it again. Take Special Care with this product Ask your healthcare professional, e.g. a doctor or pharmacist, if you need more information or This product contains alcohol (45% ethanol), i.e. advice. up to 2.25 ml per 5 ml dose, (equivalent to 45 ml beer or 18.8 ml wine), and may be harmful to If the condition worsens or symptoms do not those suffering from alcoholism. improve after 2 weeks, a qualified healthcare professional, e.g. a doctor or pharmacist, should be To be taken into account in pregnant or consulted.
    [Show full text]