Driscoll 1 Ira Driscoll, Phd Address

Total Page:16

File Type:pdf, Size:1020Kb

Driscoll 1 Ira Driscoll, Phd Address Driscoll 1 Ira Driscoll, PhD Address: University of Wisconsin – Milwaukee Psychology Department 224 Garland Hall 2441 E. Harford Ave. Milwaukee, WI 53211 USA Contact Information: Office phone: (414) 229-6665 Fax: (414) 229-5219 Email: [email protected] Current Position: Assistant Professor EDUCATION 2005-2010 Post-doctoral Fellow National Institute on Aging, USA 2005 Ph.D. Neuroscience University of Lethbridge, Canada 2002 M.S. Psychology University of New Mexico, USA 2000 B.A. Psychology University of New Mexico, USA B.A. Sociology FUNDING Current 2014-2017 Darrel K Royal Research Fund for Alzheimer’s Disease Co-PI Enhancing cognitive performance through reconsolidation mechanisms. 2013-2014 Clinical and Translational Science Institute Pilot Grant – MCW Co-PI Reduced neural synchrony of attention and default-mode networks during auditory attention in aging. 2011-2015 National Institute on Aging Grant 1 K99R00 AG032361-01 PI Genetic and hormonal contributions to age-related cognitive decline and dementia. Driscoll 2 Completed 2002-2003 Canadian Institute for Health Research (CIHR pilot grant) Co-PI The aging hippocampus: Enhancing neurogenesis and promoting survival. 2003 Pilot Grant/Dissertation Support, National Institute on Aging PI The aging hippocampus: a multi-level analysis in the rat. Honors and Awards 2014 Investigator Award (Alzheimer’s Association of South-Eastern WI) 2006 National Institute on Aging Fellows Award for Research Excellence 2005 Gold Medal of the Governor General of Canada 2004-2005 NeuroscienceCanada 2004-2005 Alberta Heritage Foundation for Medical Research (AHFMR) Studentship 2004-2005 Doctoral Research Award, Heart & Stroke Foundation of Canada (declined) 2005 The 10th Annual Graylyn Conference on Women’s Health Poster and Travel Award 2001-2004 National Science Foundation Graduate Research Fellowship 2004 International Society for Magnetic Resonance in Medicine Student Travel Assistance 2002 International Society for Magnetic Resonance in Medicine Student Travel Assistance 2001 Research Award, University of New Mexico 1998-2000 Zia Transfer Scholarship, State of New Mexico 1998-2000 Dean’s List, University of New Mexico PROFESSIONAL AFFILIATIONS Alzheimer’s Association Society for Neuroscience International Society for Magnetic Resonance in Medicine Cognitive Neuroscience Society PROFESSIONAL EXPERIENCE AND LEADERSHIP Professional Responsibilities • Judge, National Institute on Aging Fellows Award for Research Excellence Guest Editor – Current Alzheimer’s Research Driscoll 3 Ad Hoc Reviewer • Nature Reviews Neurology, PLoS One, Hippocampus, Neurobiology of Aging, Cerebral Cortex, Acta Neuropathologica, Neuroscience, Alzheimer Disease & Associated Disorders, Alzheimer’s and Dementia, Journal of Gerontology & Geriatric Research, European Journal of Neuroscience, Behavioural Brain Research, Journal of Neuroendocrinology, Brain Research, Brain and Cognition, Neuroscience Letters, Psychoneuroendocrinology, Neurobiology of Learning and Memory, Experimental Psychology, Physiology and Behavior, Behavioral Neuroscience, Neurochemistry International, Future Medicine, Wiley–Blackwell TEACHING EXPERIENCE • Physiological Psychology (Psych 254) University of Wisconsin - Milwaukee • Advanced Physiological Psychology (Psych 654) University of Wisconsin - Milwaukee • Psychology of Aging (Psych 680) University of Wisconsin - Milwaukee • Behavioral Neuroscience (Psych 854) University of Wisconsin - Milwaukee • Summer Journal Club NIA/NIH • Contemporary Problems in Brain, Behaviour and Cognitive Science Canadian Centre for Behavioural Neuroscience. University of Lethbridge PUBLICATIONS Manuscripts (in preparation) 1. Korthauer LE, Nowak NT, Moffat SD, An Y, Rowland LM, Barker P, Ferrucci L, Resnick SM, Driscoll I (in preparation). Longitudinal assessment of virtual Morris Water Maze performance and associations with regional brain volumes in older adults. 2. Driscoll I, et al. (in preparation). A candidate gene study of genetic risk for dementia and Mild Cognitive Impairment (MCI) in older, post-menopausal women: Results from the Women’s Health Initiative Memory Study (WHIMS). 3. Driscoll I, Snively B, Rossom R, Manson J, Ockene J, Vitolins M, Shumaker S, Espeland M (in preparation). Relationship between caffeine intake with global cognitive function and the risk of cognitive impairment: Results from the Women’s Health Initiative Memory Study (WHIMS). 4. Frahmand M, Nowak NT, Driscoll I, Moffat SD (in preparation). Relationships between Sex Steroid Hormones and Cognition in Men and Women. Driscoll 4 Manuscripts (under review) 1. Driscoll I, Gaussoin S, Wassertheil-Smoller S, Limacher M, Casanova RL, Yaffe K, Resnick SM, Espeland MA (Obesity). Obesity and brain volume in post-menopausal women: The Women’s Health Initiative Magnetic Resonance Imaging Study (WHIMS-MRI). 2. Chen JC, Wang X, Wellenius GA, Serre ML, Driscoll I, Casanova R, McArdle JJ, Manson JE, Chui HC, Espeland MA (Arch Neurol). Ambient Air Pollution and Neurotoxicity on Brain Structure: Evidence from Women’s Health Initiative Memory Study. 3. Nowak NT, Murali A, Driscoll I (Journal of Environmental Psychology). Navigation-related experience affects sex differences in computerized maze performance. Manuscripts (published and in press) 33. Goveas JS, Rapp S, Hogan PE, Driscoll I, Tindle HA, Smith JC, Kesler SR, Zaslavsky O, Rossom RC, Ockene JK, Yaffe K, Manson JE, Resnick SM, Espeland MA (in press). Correlates of optimal cognitive aging in 80+ women: The Women’s Health Initiative Memory Study (WHIMS). Journal of Gerontology: Series A – Medical Sciences. 32. Driscoll I, Troncoso JC, Rudow G, Sojkova J, Pletnikova O, Zhou Y, Kraut MA, Ferrucci L, Mathis CA, Klunk WE, O'Brien RJ, Davatzikos C, Wong DF, Resnick SM (2012). Correspondence between in vivo (11)C-PiB-PET amyloid imaging and postmortem, region-matched assessment of plaques. Acta Neuropathol. 124(6):823-31. 31. Driscoll I, Martin B, An Y, Maudsley S, Ferrucci L, Mattson MP, Resnick SM (2012). Plasma BDNF is associated with age-related white matter atrophy but not with cognitive function in older, non-demented adults. PLoS One. 7(4):e35217. 30. Driscoll I, Beydoun MA, An Y, Davatzikos C, Ferrucci L, Zonderman AB, Resnick SM (2012). Midlife obesity and trajectories of brain volume changes in older adults. Human Brain Mapping. 33(9):2204-10. 29. Driscoll I, Troncoso J (2011). Brain resilience and plasticity in the face of Alzheimer pathology. Curr Alzheimer Res. 8(4):329. 28. Driscoll I, Troncoso J (2011). Asymptomatic Alzheimer's disease: a prodrome or a state of resilience? Curr Alzheimer Res. 8(4):330-5. 27. Driscoll I, Espeland MA, Wassertheil-Smoller S, Gaussoin SA, Ding J, Granek IA, Ockene JK, Phillips LS, Yaffe K, Resnick SM; Women's Health Initiative Study of Cognitive Aging (2011). Weight change and cognitive function: findings from the Women's Health Initiative Study of Cognitive Aging. Obesity (Silver Spring). 19(8):1595-600. doi: 10.1038/oby.2011.23. Epub 2011 Mar 10. 26. Sojkova J, Driscoll I, Iacono D, Zhou Y, Codispoti KE, Kraut MA, Ferrucci L, Pletnikova O, Mathis CA, Klunk WE, O'Brien RJ, Wong DF, Troncoso JC, Resnick SM (2011). In vivo fibrillar beta- amyloid detected using [11C]PiB positron emission tomography and neuropathologic assessment in older adults. Arch Neurol. 68(2):232-40. 25. Driscoll I, Zhou Y, An Y, Sojkova J, Davatzikos C, Kraut MA, Ye W, Ferrucci L, Mathis CA, Klunk WE, Wong DF, Resnick SM (2011). Lack of association between (11)C-PiB and longitudinal Driscoll 5 brain atrophy in non-demented older individuals. Neurobiol Aging. 32(12):2123-30. Epub 2010 Feb 21. 24. Golden E, Emiliano A, Maudsley S, Windham BG, Carlson OD, Egan JM, Driscoll I, Resnick SM, Ferrucci L, Martin B, and Mattson MP (2010). Circulating brain-derived neurotrophic factor and indices of metabolic and cardiovascular health: data from the Baltimore Longitudinal Study of Aging. PLoS One 9;5(4):e10099. 23. Driscoll I, Davatzikos C, An Y, Wu X, Shen D, Kraut M, Resnick SM (2009). Longitudinal pattern of regional brain volume change differentiates normal aging from MCI. Neurology 72(22):1906-1913. 22. O'Brien RJ, Resnick SM, Zonderman AB, Ferrucci L, Crain BJ, Pletnikova O, Rudow G, Iacono D, Riudavets MA, Driscoll I, Price DL, Martin LJ, Troncoso JC (2009). Neuropathologic Studies of the Baltimore Longitudinal Study of Aging (BLSA). J Alzheimer’s Dis. 2009 Aug 3. [Epub ahead of print] 21. Monfils MH, Driscoll I, Vavrek R, Kolb B, Fouad K (2008). FGF-2-induced functional improvement from neonatal motor cortex injury via corticospinal projections. Exp Brain Res 185(3):453-60. 20. Driscoll I, Hong NS, Craig LA, Sutherland RJ, McDonald RJ (2008).Enhanced cell death and learning deficits after a mini-stroke in aged hippocampus. Neurobiol Aging 29(12); 1847-1858. 19. Driscoll I, Resnick SM (2007). Testosterone and cognition in normal aging and Alzheimer’s disease: An update. Current Alzheimer Research 4 (1): 33-45. Review. 18. Resnick SM, Driscoll I, Lamar M. Vulnerability of the Orbitofrontal Cortex to Age-Associated Structural and Functional Brain Changes (2007). Ann N Y Acad Sci 1121:562-75. Review. 17. Driscoll I, Monfils MH, Flynn C, Teskey GC, Kolb B (2007). Neurophysiological properties of cells filling the neonatal medial prefrontal cortex lesion cavity. Brain Res 1178:38-43. 16. Driscoll I, Resnick SM, Troncoso JC, An Y, O’Brien R, Zonderman AB (2006). Impact of Alzheimer pathology on cognitive trajectories in non-demented elderly. Annals of Neurology 60 (6), 688-695. 15. Monfils MH, Driscoll
Recommended publications
  • Final Version
    REWARD LIST ‐ RANK C JCR 2018 ‐CiteScore 2018 WOS Edition/ Scopus Main Rank Subject Category Journal Title ISSN Subject Area code IEEE TRANSACTIONS ON ULTRASONICS SCIE ACOUSTICS 08853010 C FERROELECTRICS AND FREQUENCY SCIE ACOUSTICS JOURNAL OF VIBRATION AND CONTROL 10775463 C SCIE AGRICULTURAL ECONOMICS & POLICY JOURNAL OF AGRICULTURAL ECONOMICS 0021857X C SCIE AGRICULTURAL ENGINEERING BIOMASS & BIOENERGY 09619534 C SCIE AGRICULTURE, DAIRY & ANIMAL SCIENCE ANIMAL REPRODUCTION SCIENCE 03784320 C SCIE AGRICULTURE, DAIRY & ANIMAL SCIENCE APPLIED ANIMAL BEHAVIOUR SCIENCE 01681591 C SCIE AGRICULTURE, DAIRY & ANIMAL SCIENCE ARCHIVES OF ANIMAL NUTRITION 1745039X C JOURNAL OF ANIMAL PHYSIOLOGY AND SCIE AGRICULTURE, DAIRY & ANIMAL SCIENCE 09312439 C ANIMAL NUTRITION SCIE AGRICULTURE, DAIRY & ANIMAL SCIENCE Animals 20762615 C SCIE AGRICULTURE, MULTIDISCIPLINARY Journal of Land Use Science 1747423X C RENEWABLE AGRICULTURE AND FOOD SCIE AGRICULTURE, MULTIDISCIPLINARY 17421705 C SYSTEMS SCIE AGRICULTURE, MULTIDISCIPLINARY ANNALS OF APPLIED BIOLOGY 00034746 C SCIE AGRICULTURE, MULTIDISCIPLINARY CALIFORNIA AGRICULTURE 00080845 C SCIE AGRONOMY PLANT PATHOLOGY 00320862 C SCIE AGRONOMY IRRIGATION SCIENCE 03427188 C SCIE AGRONOMY Rice Science 16726308 C SCIE AGRONOMY Agronomy‐Basel 20734395 C SCIE AGRONOMY CROP PROTECTION 02612194 C SCIE AGRONOMY EXPERIMENTAL AGRICULTURE 00144797 C JOURNAL OF PLANT NUTRITION AND SOIL SCIE AGRONOMY 14368730 C SCIENCE SCIE ALLERGY CONTACT DERMATITIS 01051873 C SCIE ALLERGY Allergy Asthma & Immunology Research 20927355 C Advances
    [Show full text]
  • SCIENCE CITATION INDEX EXPANDED - JOURNAL LIST Total Journals: 8631
    SCIENCE CITATION INDEX EXPANDED - JOURNAL LIST Total journals: 8631 1. 4OR-A QUARTERLY JOURNAL OF OPERATIONS RESEARCH 2. AAPG BULLETIN 3. AAPS JOURNAL 4. AAPS PHARMSCITECH 5. AATCC REVIEW 6. ABDOMINAL IMAGING 7. ABHANDLUNGEN AUS DEM MATHEMATISCHEN SEMINAR DER UNIVERSITAT HAMBURG 8. ABSTRACT AND APPLIED ANALYSIS 9. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 10. ACADEMIC EMERGENCY MEDICINE 11. ACADEMIC MEDICINE 12. ACADEMIC PEDIATRICS 13. ACADEMIC RADIOLOGY 14. ACCOUNTABILITY IN RESEARCH-POLICIES AND QUALITY ASSURANCE 15. ACCOUNTS OF CHEMICAL RESEARCH 16. ACCREDITATION AND QUALITY ASSURANCE 17. ACI MATERIALS JOURNAL 18. ACI STRUCTURAL JOURNAL 19. ACM COMPUTING SURVEYS 20. ACM JOURNAL ON EMERGING TECHNOLOGIES IN COMPUTING SYSTEMS 21. ACM SIGCOMM COMPUTER COMMUNICATION REVIEW 22. ACM SIGPLAN NOTICES 23. ACM TRANSACTIONS ON ALGORITHMS 24. ACM TRANSACTIONS ON APPLIED PERCEPTION 25. ACM TRANSACTIONS ON ARCHITECTURE AND CODE OPTIMIZATION 26. ACM TRANSACTIONS ON AUTONOMOUS AND ADAPTIVE SYSTEMS 27. ACM TRANSACTIONS ON COMPUTATIONAL LOGIC 28. ACM TRANSACTIONS ON COMPUTER SYSTEMS 29. ACM TRANSACTIONS ON COMPUTER-HUMAN INTERACTION 30. ACM TRANSACTIONS ON DATABASE SYSTEMS 31. ACM TRANSACTIONS ON DESIGN AUTOMATION OF ELECTRONIC SYSTEMS 32. ACM TRANSACTIONS ON EMBEDDED COMPUTING SYSTEMS 33. ACM TRANSACTIONS ON GRAPHICS 34. ACM TRANSACTIONS ON INFORMATION AND SYSTEM SECURITY 35. ACM TRANSACTIONS ON INFORMATION SYSTEMS 36. ACM TRANSACTIONS ON INTELLIGENT SYSTEMS AND TECHNOLOGY 37. ACM TRANSACTIONS ON INTERNET TECHNOLOGY 38. ACM TRANSACTIONS ON KNOWLEDGE DISCOVERY FROM DATA 39. ACM TRANSACTIONS ON MATHEMATICAL SOFTWARE 40. ACM TRANSACTIONS ON MODELING AND COMPUTER SIMULATION 41. ACM TRANSACTIONS ON MULTIMEDIA COMPUTING COMMUNICATIONS AND APPLICATIONS 42. ACM TRANSACTIONS ON PROGRAMMING LANGUAGES AND SYSTEMS 43. ACM TRANSACTIONS ON RECONFIGURABLE TECHNOLOGY AND SYSTEMS 44.
    [Show full text]
  • Jennifer I. Luebke 1 Curriculum Vitae Jennifer I. Luebke, Ph.D. Associate
    Jennifer I. Luebke Curriculum Vitae Jennifer I. Luebke, Ph.D. Associate Professor of Anatomy & Neurobiology Associate Professor of Psychiatry Director, Laboratory of Cellular Neurobiology Boston University School of Medicine 85 East Newton Street, M949 Boston, Massachusetts 02118 Voice: 617-638-4930 Email: [email protected] Education and Employment History: 1980-1984: B.S. (Biology) Randolph-Macon College, Ashland, Virginia 1984-1986: Laboratory Technician (Laboratory of Cell Biology and Genetics, NIDDK) National Institutes of Health, Bethesda, Maryland 1986-1990: Ph.D. Student (Anatomy & Neurobiology), Boston University School of Medicine, Boston, Massachusetts (Linda L. Wright, mentor) 1990-1992: Postdoctoral Fellow, Department of Psychiatry, Harvard Medical School, Boston, Massachusetts (Robert W. McCarley and Robert W. Greene mentors) 1992-1995: Postdoctoral Fellow, Department of Physiology, Tufts University Medical School, Boston, Massachusetts (Kathleen Dunlap, mentor) 1995-2003: Assistant Professor, Department of Anatomy & Neurobiology and Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts 2004-Present: Associate Professor, Department of Anatomy & Neurobiology and Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts 2010-Present: Adjunct Associate Professor, Department of Neuroscience, Mount Sinai School of Medicine, New York, New York Research Summary: Research is directed toward understanding alterations in the structure and function of individual cortical pyramidal cells in a rhesus monkey model of normal aging and in transgenic mouse models of neurodegenerative disease. Using whole-cell patch-clamp methods and ultra-high resolution confocal microscopy, Dr. Luebke has demonstrated marked alterations in action potential firing patterns (and underlying ionic currents), glutamatergic and GABAergic synaptic response properties and detailed dendritic and spine architecture in cortical pyramidal cells both in normal aging and in mouse models of neurodegenerative disease.
    [Show full text]
  • Predicting Cognitive Decline: Genetic, Environmental and Lifestyle Risk Factors
    Predicting Cognitive Decline: Genetic, Environmental and Lifestyle Risk Factors Shea J. Andrews April 2017 A thesis by compilation submitted for the degree of Doctor of Philosophy of The Australian National University © Copyright by Shea John Frederick Andrews 2017 All Rights Reserved i Declaration This work was conducted from February 2013 to August 2016 at the Genome Diversity and Health Group, John Curtin School of Medical Research, The Australian National University, Canberra, ACT. This thesis by compilation consists of five original publications describing the analyses I have performed during my candidature investigating the role of genetic, environmental and lifestyle risk factors in normal cognitive aging. All five publications have been published in Q1 ranked journals according to the SCImago Journal & Country Rankings in the fields of neurology, genetics, psychiatry and mental health, and geriatric and gerontology. My specific contribution to each manuscript is detailed in the subsequent pages in the form of a statement signed by the senior author of each publication. This document has not been submitted for qualifications at any other academic institution. Shea Andrews Canberra, Australia April 2017 ii Published Papers Andrews, SJ, Das, D., Anstey, KJ., Easteal, S. (2015). Interactive effect of APOE genotype and blood pressure on cognitive decline: The PATH through life project. Journal of Alzheimer's Disease. 44(4): 1087-98. DOI: 10.3233/JAD- 140630 For this publication, I designed and performed all statistical analyses and wrote the manuscript. A slightly modified version of this paper is presented in Chapter 3. ____________________ Simon Easteal Senior Author April 2017 Andrews SJ, Das D, Cherbuin N, Anstey KJ, Easteal S.
    [Show full text]
  • Brain Ageing in the New Millennium
    Brain ageing in the new millennium Julian N. Trollor, Michael J. Valenzuela Objective: This paper examines the current literature pertaining to brain ageing. The objective of this review is to provide an overview of the effects of ageing on brain structure and function and to examine possible mediators of these changes. Methods: A MEDLINE search was conducted for each area of interest. A selective review was undertaken of relevant articles. Results: Although fundamental changes in fluid intellectual abilities occur with age, global cognitive decline is not a hallmark of the ageing process. Decline in fluid intellectual ability is paralleled by regionally specific age related changes apparent from both structural and functional neuroimaging studies. The histopathological mediators of these changes do not appear to be reduction in neuronal number, which, with the exception of selected hippo- campal regions, remain relatively stable across age. At the molecular level, several mech- anisms of age related change have been postulated. Such theoretical models await refinement and may eventually provide a basis for therapy designed to reduce effects of the ageing process. The role of possible protective factors such as ‘brain reserve’, neuro- protective agents and hormonal factors in modifying individual vulnerability to the ageing process has been the focus of a limited number of studies. Conclusion: Our understanding of the functional and structural changes associated with both healthy and pathological ageing is rapidly gaining in sophistication and complexity. An awareness of the fundamental biological substrates underpinning the ageing process will allow improved insights into vulnerability to neuropsychiatric disease associated with advancing age. Key words: brain ageing, cognition, dementia, neuroimaging.
    [Show full text]
  • The Effects of Normal Aging on Myelin and Nerve Fibers: a Review∗
    Journal of Neurocytology 31, 581–593 (2002) The effects of normal aging on myelin and nerve fibers: A review∗ ALAN PETERS Department of Anatomy and Neurobiology, Boston University School of Medicine, 715, Albany Street, Boston, MA 02118, USA [email protected] Received 7 January 2003; revised 4 March 2003; accepted 5 March 2003 Abstract It was believed that the cause of the cognitive decline exhibited by human and non-human primates during normal aging was a loss of cortical neurons. It is now known that significant numbers of cortical neurons are not lost and other bases for the cognitive decline have been sought. One contributing factor may be changes in nerve fibers. With age some myelin sheaths exhibit degenerative changes, such as the formation of splits containing electron dense cytoplasm, and the formation on myelin balloons. It is suggested that such degenerative changes lead to cognitive decline because they cause changes in conduction velocity, resulting in a disruption of the normal timing in neuronal circuits. Yet as degeneration occurs, other changes, such as the formation of redundant myelin and increasing thickness suggest of sheaths, suggest some myelin formation is continuing during aging. Another indication of this is that oligodendrocytes increase in number with age. In addition to the myelin changes, stereological studies have shown a loss of nerve fibers from the white matter of the cerebral hemispheres of humans, while other studies have shown a loss of nerve fibers from the optic nerves and anterior commissure in monkeys. It is likely that such nerve fiber loss also contributes to cognitive decline, because of the consequent decrease in connections between neurons.
    [Show full text]
  • Technology and Aging in America (Part 14 Of
    Appendix B The Cell Biology of Aging Introduction spans that seem to be “programmed” into them accord- ing to species. Mechanisms underlying this programmed The distinction between the effects of aging as a aging could involve an intrinsic genetic component of chronological process and diseases whose prevalence the tissues (24), and/or an extrinsic “neuroendocrine increase with advancing age remains blurred. Condi- pacemaker” (16,17). tions once thought to be inevitable companions of old The genetic version of the biological clock is bol- age are now known to in fact be pathological in origin stered by the observation that the survival time of and thus possibly treatable and preventable. One ex- tissues grafted (or transferred) from an older animal ample is senile dementia, no longer the mysterious fate into a younger one of the same species seems to de- of the very old, but often a clinical manifestation of pend on the age of the donor and is not influenced arteriosclerotic or biochemical brain disease. by the “younger” environment into which it has been Further research may elucidate the mechanisms introduced (24). Similarly, when nuclei from younger underlying aging and their possible connection to age- cells are transplanted into the cytoplasm of older cells, related diseases, leading to the development of medi- the recipients then live longer and regain the ability cal techniques that delay the onset and progression to replicate. These observations all suggest that a of symptoms. While it may not lead to actual exten- “clock” controlling aging does exist and may be located sion of the human life span, such knowledge could re- in the nucleus, possibly in the genetic material (24).
    [Show full text]
  • Integrated Transcriptomic and Neuroimaging Brain Model Decodes
    RESEARCH ARTICLE Integrated transcriptomic and neuroimaging brain model decodes biological mechanisms in aging and Alzheimer’s disease Quadri Adewale1,2,3, Ahmed F Khan1,2,3, Felix Carbonell4, Yasser Iturria-Medina1,2,3*, Alzheimer’s Disease Neuroimaging Initiative† 1Neurology and Neurosurgery Department, Montreal Neurological Institute, McGill University, Montreal, Canada; 2McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Canada; 3Ludmer Centre for Neuroinformatics and Mental Health, McGill University, Montreal, Canada; *For correspondence: 4Biospective Inc, Montreal, Canada [email protected] †Data used in preparation of this article were partly obtained from the Alzheimer’s Disease Abstract Both healthy aging and Alzheimer’s disease (AD) are characterized by concurrent Neuroimaging Initiative (ADNI) alterations in several biological factors. However, generative brain models of aging and AD are database (adni.loni.usc.edu). As limited in incorporating the measures of these biological factors at different spatial resolutions. such, the investigators within the Here, we propose a personalized bottom-up spatiotemporal brain model that accounts for the ADNI contributed to the design direct interplay between hundreds of RNA transcripts and multiple macroscopic neuroimaging and implementation of ADNI modalities (PET, MRI). In normal elderly and AD participants, the model identifies top genes and/or provided data but did not modulating tau and amyloid-b burdens, vascular flow, glucose metabolism, functional activity, and participate in analysis or writing atrophy to drive cognitive decline. The results also revealed that AD and healthy aging share of this report. A complete listing specific biological mechanisms, even though AD is a separate entity with considerably more altered of ADNI investigators can be pathways.
    [Show full text]
  • Download Download
    NeuroRegulation The Official Journal of . Volume 8, Number 1, 2021 NeuroRegulation Editor-in-Chief Rex L. Cannon, PhD: SPESA Research Institute, Knoxville, TN, USA Executive Editor Nancy L. Wigton, PhD: 1) Grand Canyon University, Phoenix, AZ, USA; 2) Applied Neurotherapy Center, Tempe, AZ, USA Associate Editors Scott L. Decker, PhD: University of South Carolina, Department of Psychology, Columbia, SC, USA Jon A. Frederick, PhD: Lamar University, Beaumont, TX, USA Genomary Krigbaum, PsyD: University of Wyoming, Family Medicine Residency, Casper, WY, USA Randall Lyle, PhD: Mount Mercy University, Cedar Rapids, IA, USA Tanya Morosoli, MSc: 1) Clínica de Neuropsicología Diagnóstica y Terapéutica, Mexico City, Mexico; 2) ECPE, Harvard T. H. Chan School oF Public Health, Boston, MA, USA Sarah Prinsloo, PhD: MD Anderson Cancer Center, Houston, TX, USA Deborah Simkin, MD: 1) Emory University School of Medicine, Department of Psychiatry, Atlanta, GA, USA; 2) Attention, Memory, and Cognition Center, Destin, FL, USA Estate M. Sokhadze, PhD: University of South Carolina, School of Medicine Greenville, Greenville, SC, USA Larry C. Stevens, PhD: Northern Arizona University, Department of Psychological Services, Flagstaff, AZ, USA Tanju Surmeli, MD: Living Health Center for Research and Education, Sisli, Istanbul, Turkey Production Editor Jacqueline Luk Paredes, Phoenix, AZ, USA NeuroRegulation (ISSN: 2373-0587) is published quarterly by the International Society for Neurofeedback and Research (ISNR), 13876 SW 56th Street, PMB 311, Miami, FL 33175-6021, USA. Copyright NeuroRegulation is open access with no submission fees or APC (Author Processing Charges). This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge.
    [Show full text]
  • 2020-21 Student Handbook for Pharmacology and Neuroscience
    Pharmacology and Neuroscience Student Handbook 2020-2021 The information provided in this document serves to supplement the requirements of the Graduate School of Biomedical Sciences detailed in the UNTHSC Catalog with requirements specific to the discipline of Pharmacology and Neuroscience. Table of Contents Page Description of the Pharmacology & Neuroscience Discipline ........ 3 Graduate Faculty and Their Research ............................................. 4 Requirements ................................................................................. 18 Required Courses ..................................................................... 18 Journal Club and Seminar Courses .......................................... 18 Works in Progress .................................................................... 18 Elective Courses ....................................................................... 18 Sample Degree Plans ..................................................................... 20 Advancement to Candidacy ........................................................... 23 2 Pharm & Neuro Discipline Handbook (8/6/2020) Pharmacology & Neuroscience Discipline Nathalie Sumien, Ph.D., Graduate Advisor Center for BioHealth Building, Room 517 817-735-2389 [email protected] Graduate Faculty: Barber, Basu, Borgmann, Chaturvedula, Clark, R. Cunningham, Das, Dong, Forster, Gatch, Goulopoulou, Hall, Huang, Jin, Johnson, R. Liu, Y. Liu, Luedtke, Mallet, Nejtek, O’Bryant, Park, Phillips, L. Prokai, K. Prokai, Roane, Salvatore, A.
    [Show full text]
  • Listado De Revistas Extranjeras Homologadas 2019
    Código: M304PR03F01 DEPARTAMENTO LISTADO REVISTAS Versión: 04 ADMINISTRATIVO DE CIENCIA, TECNOLOGÍA E HOMOLOGADAS Fecha: 2018-09-20 INNOVACIÓN Página: 1 de 1 No. NOMBRE ISSN CATEGORIA VIGENCIA LISTA_SIR Enero 2019 - Scimago Journal Rank - SJR; Journal 1 COMMUNICATIONS OF THE ACM 0001-0782; 1557-7317 A1 Diciembre 2020 Citation Reports - JCR; Enero 2019 - Scimago Journal Rank - SJR; Journal 2 AIAA JOURNAL 0001-1452; 1533-385X A1 Diciembre 2020 Citation Reports - JCR; Enero 2019 - Scimago Journal Rank - SJR; Journal 3 AICHE JOURNAL 0001-1541; 1547-5905 A1 Diciembre 2020 Citation Reports - JCR; Enero 2019 - Scimago Journal Rank - SJR; Journal 4 AORN JOURNAL 0001-2092; 1878-0369 A2 Diciembre 2020 Citation Reports - JCR; Enero 2019 - 5 Archiv fur Rechts- und Sozialphilosophie 0001-2343 B Scimago Journal Rank - SJR; Diciembre 2020 0001-2491; 0364-9962; Enero 2019 - Scimago Journal Rank - SJR; Journal 6 ASHRAE JOURNAL B 1943-6637 Diciembre 2020 Citation Reports - JCR; Enero 2019 - 7 Planning 0001-2610 C Scimago Journal Rank - SJR; Diciembre 2020 Enero 2019 - Scimago Journal Rank - SJR; Journal 8 SEMINARS IN NUCLEAR MEDICINE 0001-2998; 1558-4623 A1 Diciembre 2020 Citation Reports - JCR; Enero 2019 - Scimago Journal Rank - SJR; Journal 9 Abacus 0001-3072; 1467-6281 A2 Diciembre 2020 Citation Reports - JCR; Enero 2019 - Scimago Journal Rank - SJR; Journal 10 ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS 0001-3765; 1678-2690 A1 Diciembre 2020 Citation Reports - JCR; Enero 2019 - Scimago Journal Rank - SJR; Journal 11 BULLETIN DE L ACADEMIE NATIONALE DE
    [Show full text]
  • Dr. F. Gonzalez-Lima CV Updated Jan. 10, 2017
    (Updated January 10, 2017) CURRICULUM VITAE Francisco Gonzalez-Lima 1. POSITION George I. Sanchez Centennial Professorship in Liberal Arts and Sciences Professor, Behavioral Neuroscience Area, Department of Psychology, College of Liberal Arts Professor, Division of Pharmacology and Toxicology, College of Pharmacy Professor, Institute for Neuroscience, College of Natural Sciences, Graduate Studies Program The University of Texas at Austin 2. ADDRESS The University of Texas at Austin, 108 E. Dean Keeton Stop A8000, Austin, TX 78712-1043, USA. Home: 5739 Merrywing Circle, Austin, TX 78730-1411, USA. Phone: Cell (512) 202-7375, Office (512) 475-8497, Fax (512) 910-8247. Email: [email protected] Webpage: http://www.utexas.edu/cola/depts/psychology/faculty/fg 3. EDUCATION B.S., Biology, Tulane University, New Orleans, Louisiana, USA, 1976. B.A., Psychology, Tulane University, New Orleans, Louisiana, USA, 1977. Ph.D., Anatomy and Neurobiology, Biomedical Sciences Graduate Program, School of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico, USA, 1980. Postdoctoral Research Fellow, Behavioral Neuroscience, Alexander von Humboldt Foundation, Technische Universität Darmstadt, Germany, 1983. 4. EXPERIENCE 4.1. Appointments Assistant Professor 1980-83, Associate Professor 1983-85, Department of Anatomy, Ponce School of Medicine, Ponce, Puerto Rico, USA. Assistant Professor 1986-90, Department of Anatomy and Neurobiology, College of Medicine, Texas A&M University, College Station, Texas, USA. Associate Professor 1991-96, Professor 1997-present, Head 1997-2001, Behavioral Neuroscience Area, George I. Sanchez Centennial Professorship in Liberal Arts and Sciences 2000-present, Director 2002-2011, Texas Consortium in Behavioral Neuroscience, Departments of Psychology, Pharmacology and Toxicology, Institute for Neuroscience, Imaging Research Center and Center for Behavioral Neuroendocrinology, The University of Texas at Austin, Texas, USA.
    [Show full text]