Driscoll 1 Ira Driscoll, Phd Address
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Driscoll 1 Ira Driscoll, PhD Address: University of Wisconsin – Milwaukee Psychology Department 224 Garland Hall 2441 E. Harford Ave. Milwaukee, WI 53211 USA Contact Information: Office phone: (414) 229-6665 Fax: (414) 229-5219 Email: [email protected] Current Position: Assistant Professor EDUCATION 2005-2010 Post-doctoral Fellow National Institute on Aging, USA 2005 Ph.D. Neuroscience University of Lethbridge, Canada 2002 M.S. Psychology University of New Mexico, USA 2000 B.A. Psychology University of New Mexico, USA B.A. Sociology FUNDING Current 2014-2017 Darrel K Royal Research Fund for Alzheimer’s Disease Co-PI Enhancing cognitive performance through reconsolidation mechanisms. 2013-2014 Clinical and Translational Science Institute Pilot Grant – MCW Co-PI Reduced neural synchrony of attention and default-mode networks during auditory attention in aging. 2011-2015 National Institute on Aging Grant 1 K99R00 AG032361-01 PI Genetic and hormonal contributions to age-related cognitive decline and dementia. Driscoll 2 Completed 2002-2003 Canadian Institute for Health Research (CIHR pilot grant) Co-PI The aging hippocampus: Enhancing neurogenesis and promoting survival. 2003 Pilot Grant/Dissertation Support, National Institute on Aging PI The aging hippocampus: a multi-level analysis in the rat. Honors and Awards 2014 Investigator Award (Alzheimer’s Association of South-Eastern WI) 2006 National Institute on Aging Fellows Award for Research Excellence 2005 Gold Medal of the Governor General of Canada 2004-2005 NeuroscienceCanada 2004-2005 Alberta Heritage Foundation for Medical Research (AHFMR) Studentship 2004-2005 Doctoral Research Award, Heart & Stroke Foundation of Canada (declined) 2005 The 10th Annual Graylyn Conference on Women’s Health Poster and Travel Award 2001-2004 National Science Foundation Graduate Research Fellowship 2004 International Society for Magnetic Resonance in Medicine Student Travel Assistance 2002 International Society for Magnetic Resonance in Medicine Student Travel Assistance 2001 Research Award, University of New Mexico 1998-2000 Zia Transfer Scholarship, State of New Mexico 1998-2000 Dean’s List, University of New Mexico PROFESSIONAL AFFILIATIONS Alzheimer’s Association Society for Neuroscience International Society for Magnetic Resonance in Medicine Cognitive Neuroscience Society PROFESSIONAL EXPERIENCE AND LEADERSHIP Professional Responsibilities • Judge, National Institute on Aging Fellows Award for Research Excellence Guest Editor – Current Alzheimer’s Research Driscoll 3 Ad Hoc Reviewer • Nature Reviews Neurology, PLoS One, Hippocampus, Neurobiology of Aging, Cerebral Cortex, Acta Neuropathologica, Neuroscience, Alzheimer Disease & Associated Disorders, Alzheimer’s and Dementia, Journal of Gerontology & Geriatric Research, European Journal of Neuroscience, Behavioural Brain Research, Journal of Neuroendocrinology, Brain Research, Brain and Cognition, Neuroscience Letters, Psychoneuroendocrinology, Neurobiology of Learning and Memory, Experimental Psychology, Physiology and Behavior, Behavioral Neuroscience, Neurochemistry International, Future Medicine, Wiley–Blackwell TEACHING EXPERIENCE • Physiological Psychology (Psych 254) University of Wisconsin - Milwaukee • Advanced Physiological Psychology (Psych 654) University of Wisconsin - Milwaukee • Psychology of Aging (Psych 680) University of Wisconsin - Milwaukee • Behavioral Neuroscience (Psych 854) University of Wisconsin - Milwaukee • Summer Journal Club NIA/NIH • Contemporary Problems in Brain, Behaviour and Cognitive Science Canadian Centre for Behavioural Neuroscience. University of Lethbridge PUBLICATIONS Manuscripts (in preparation) 1. Korthauer LE, Nowak NT, Moffat SD, An Y, Rowland LM, Barker P, Ferrucci L, Resnick SM, Driscoll I (in preparation). Longitudinal assessment of virtual Morris Water Maze performance and associations with regional brain volumes in older adults. 2. Driscoll I, et al. (in preparation). A candidate gene study of genetic risk for dementia and Mild Cognitive Impairment (MCI) in older, post-menopausal women: Results from the Women’s Health Initiative Memory Study (WHIMS). 3. Driscoll I, Snively B, Rossom R, Manson J, Ockene J, Vitolins M, Shumaker S, Espeland M (in preparation). Relationship between caffeine intake with global cognitive function and the risk of cognitive impairment: Results from the Women’s Health Initiative Memory Study (WHIMS). 4. Frahmand M, Nowak NT, Driscoll I, Moffat SD (in preparation). Relationships between Sex Steroid Hormones and Cognition in Men and Women. Driscoll 4 Manuscripts (under review) 1. Driscoll I, Gaussoin S, Wassertheil-Smoller S, Limacher M, Casanova RL, Yaffe K, Resnick SM, Espeland MA (Obesity). Obesity and brain volume in post-menopausal women: The Women’s Health Initiative Magnetic Resonance Imaging Study (WHIMS-MRI). 2. Chen JC, Wang X, Wellenius GA, Serre ML, Driscoll I, Casanova R, McArdle JJ, Manson JE, Chui HC, Espeland MA (Arch Neurol). Ambient Air Pollution and Neurotoxicity on Brain Structure: Evidence from Women’s Health Initiative Memory Study. 3. Nowak NT, Murali A, Driscoll I (Journal of Environmental Psychology). Navigation-related experience affects sex differences in computerized maze performance. Manuscripts (published and in press) 33. Goveas JS, Rapp S, Hogan PE, Driscoll I, Tindle HA, Smith JC, Kesler SR, Zaslavsky O, Rossom RC, Ockene JK, Yaffe K, Manson JE, Resnick SM, Espeland MA (in press). Correlates of optimal cognitive aging in 80+ women: The Women’s Health Initiative Memory Study (WHIMS). Journal of Gerontology: Series A – Medical Sciences. 32. Driscoll I, Troncoso JC, Rudow G, Sojkova J, Pletnikova O, Zhou Y, Kraut MA, Ferrucci L, Mathis CA, Klunk WE, O'Brien RJ, Davatzikos C, Wong DF, Resnick SM (2012). Correspondence between in vivo (11)C-PiB-PET amyloid imaging and postmortem, region-matched assessment of plaques. Acta Neuropathol. 124(6):823-31. 31. Driscoll I, Martin B, An Y, Maudsley S, Ferrucci L, Mattson MP, Resnick SM (2012). Plasma BDNF is associated with age-related white matter atrophy but not with cognitive function in older, non-demented adults. PLoS One. 7(4):e35217. 30. Driscoll I, Beydoun MA, An Y, Davatzikos C, Ferrucci L, Zonderman AB, Resnick SM (2012). Midlife obesity and trajectories of brain volume changes in older adults. Human Brain Mapping. 33(9):2204-10. 29. Driscoll I, Troncoso J (2011). Brain resilience and plasticity in the face of Alzheimer pathology. Curr Alzheimer Res. 8(4):329. 28. Driscoll I, Troncoso J (2011). Asymptomatic Alzheimer's disease: a prodrome or a state of resilience? Curr Alzheimer Res. 8(4):330-5. 27. Driscoll I, Espeland MA, Wassertheil-Smoller S, Gaussoin SA, Ding J, Granek IA, Ockene JK, Phillips LS, Yaffe K, Resnick SM; Women's Health Initiative Study of Cognitive Aging (2011). Weight change and cognitive function: findings from the Women's Health Initiative Study of Cognitive Aging. Obesity (Silver Spring). 19(8):1595-600. doi: 10.1038/oby.2011.23. Epub 2011 Mar 10. 26. Sojkova J, Driscoll I, Iacono D, Zhou Y, Codispoti KE, Kraut MA, Ferrucci L, Pletnikova O, Mathis CA, Klunk WE, O'Brien RJ, Wong DF, Troncoso JC, Resnick SM (2011). In vivo fibrillar beta- amyloid detected using [11C]PiB positron emission tomography and neuropathologic assessment in older adults. Arch Neurol. 68(2):232-40. 25. Driscoll I, Zhou Y, An Y, Sojkova J, Davatzikos C, Kraut MA, Ye W, Ferrucci L, Mathis CA, Klunk WE, Wong DF, Resnick SM (2011). Lack of association between (11)C-PiB and longitudinal Driscoll 5 brain atrophy in non-demented older individuals. Neurobiol Aging. 32(12):2123-30. Epub 2010 Feb 21. 24. Golden E, Emiliano A, Maudsley S, Windham BG, Carlson OD, Egan JM, Driscoll I, Resnick SM, Ferrucci L, Martin B, and Mattson MP (2010). Circulating brain-derived neurotrophic factor and indices of metabolic and cardiovascular health: data from the Baltimore Longitudinal Study of Aging. PLoS One 9;5(4):e10099. 23. Driscoll I, Davatzikos C, An Y, Wu X, Shen D, Kraut M, Resnick SM (2009). Longitudinal pattern of regional brain volume change differentiates normal aging from MCI. Neurology 72(22):1906-1913. 22. O'Brien RJ, Resnick SM, Zonderman AB, Ferrucci L, Crain BJ, Pletnikova O, Rudow G, Iacono D, Riudavets MA, Driscoll I, Price DL, Martin LJ, Troncoso JC (2009). Neuropathologic Studies of the Baltimore Longitudinal Study of Aging (BLSA). J Alzheimer’s Dis. 2009 Aug 3. [Epub ahead of print] 21. Monfils MH, Driscoll I, Vavrek R, Kolb B, Fouad K (2008). FGF-2-induced functional improvement from neonatal motor cortex injury via corticospinal projections. Exp Brain Res 185(3):453-60. 20. Driscoll I, Hong NS, Craig LA, Sutherland RJ, McDonald RJ (2008).Enhanced cell death and learning deficits after a mini-stroke in aged hippocampus. Neurobiol Aging 29(12); 1847-1858. 19. Driscoll I, Resnick SM (2007). Testosterone and cognition in normal aging and Alzheimer’s disease: An update. Current Alzheimer Research 4 (1): 33-45. Review. 18. Resnick SM, Driscoll I, Lamar M. Vulnerability of the Orbitofrontal Cortex to Age-Associated Structural and Functional Brain Changes (2007). Ann N Y Acad Sci 1121:562-75. Review. 17. Driscoll I, Monfils MH, Flynn C, Teskey GC, Kolb B (2007). Neurophysiological properties of cells filling the neonatal medial prefrontal cortex lesion cavity. Brain Res 1178:38-43. 16. Driscoll I, Resnick SM, Troncoso JC, An Y, O’Brien R, Zonderman AB (2006). Impact of Alzheimer pathology on cognitive trajectories in non-demented elderly. Annals of Neurology 60 (6), 688-695. 15. Monfils MH, Driscoll