AH16 Aboriginal and Torres Strait Islander Health
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Structure of ATP Synthase from Paracoccus Denitrificans Determined by X-Ray Crystallography at 4.0 Å Resolution
Structure of ATP synthase from Paracoccus denitrificans determined by X-ray crystallography at 4.0 Å resolution Edgar Morales-Riosa, Martin G. Montgomerya, Andrew G. W. Leslieb,1, and John E. Walkera,1 aMedical Research Council Mitochondrial Biology Unit, Cambridge Biomedical Campus, Cambridge CB2 0XY, United Kingdom; and bMedical Research Council Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge CB2 0QH, United Kingdom Contributed by John E. Walker, September 4, 2015 (sent for review July 28, 2015; reviewed by Stanley D. Dunn, Robert H. Fillingame, and Dale Wigley) The structure of the intact ATP synthase from the α-proteobacterium mitochondrial enzyme that have no known role in catalysis (2). Paracoccus denitrificans ζ , inhibited by its natural regulatory -protein, Structures have been described of the F1 domains of the enzymes has been solved by X-ray crystallography at 4.0 Å resolution. The from Escherichia coli (10, 11), Caldalkalibacillus thermarum (12), ζ-protein is bound via its N-terminal α-helix in a catalytic interface in and Geobacillus stearothermophilus (formerly Bacillus PS3) (13); of the F1 domain. The bacterial F1 domain is attached to the membrane the α3β3-subcomplex of the F1 domain from G. stearothermophilus domain by peripheral and central stalks. The δ-subunit component of (14); and of isolated c-rings from the rotors of several species (15– the peripheral stalk binds to the N-terminal regions of two α-subunits. 19). There is also structural information on the peripheral stalk The stalk extends via two parallel long α-helices, one in each of the region of the F-ATPase from E. -
Oneida County Legislative District 1 Date: April 1, 2014
CARTER RD D D 5 R R 6 B T 3 L L I E P L P S A T K E U C E T 5 C 6 K R D D U W O 3 M R W O D E O R S E R A K T R L Y T N C E E A A S E U D H G R I C Y T O I E O E D E R ID R A R A T R N N R F D C R D E W E O R N S E G S N D R H R E T D T E E S E A L D H S E E R I R T O S T U R I 10 D R M S N W I S R A G E A C N L H R T Y Verona D R AC11 AC12 AC13 AC14 AC15 E AC16 AC17 AC18 H AC19 R C R W H T L D R E I IL D L D D R L S E VERONA 4 R E B R M U N L R D I E T A K C K H A C O O U R S 6 R TA R N D TE 2 D R T OU R LO TE W E 31 Y EL T L U D R D R D O E R R L L B N R O E S T G E N T W E D I B A R L T O D S R NS E D T A D S A M M R R R T H 4 WESTMORELAND 3 R E C E N R RO A E N R E U FR TE N D U G Y T H B R 31 D D R S I I L D E R Y 5 YD R L R 6 L BO R D 5 L R N 3 I I 6 E SPR R H A 3 ING RD M M G E D S 3 R M E L I E T O E W N U T R EL I F U L I O RD E S L R O PR I-90 R D R ING STAT D E RD I- E R T E 90 OU T T A D AD11 AD12 AD13 E AD14 T A AD15 AD16 AD17 AD18 AD19 31 S T R S I-90 I-90 H 0 T I-9 L I OW D E R M S LL S PR VERONA 3 L ING H RD IL 0 OUS H I-90 I-9 E RD FOSTE D R CORN N ERS RD A T S S N D I R A E I-90 R M O Y I-90 O IL DA 5 M D D R 36 I-90 I-90 R E S A T -90 MIT G I C HEL S E U L R WN L R D O I O D T NE N R I D R I-90 I R RD S K SK KINNE R N 0 E N T RD -9 T 5 E I I E 0 L A 6 R L 9 S A J I- P 3 D D T T S R WESTMORELAND 4 D S E Y R E A LL R E W T N E C NL D T H O O E U H C L T F I R O R I L L M E O I R O L L X M W U D IL HIL E L T R R O M 0 T I-9 A E D E O R IN AE11 AE12 AE1R 3 T AE14 D AE15 AE16 L AE17 AE18 AE19 R D S R 3 N C D 1 E EN OW TE -
CADP 2.0) Infrastructure for Connectivity and Innovation
The Comprehensive Asia Development Plan 2.0 (CADP 2.0) Infrastructure for Connectivity and Innovation November 2015 Economic Research Institute for ASEAN and East Asia The findings, interpretations, and conclusions expressed herein do not necessarily reflect the views and policies of the Economic Research Institute for ASEAN and East Asia, its Governing Board, Academic Advisory Council, or the institutions and governments they represent. All rights reserved. Material in this publication may be freely quoted or reprinted with proper acknowledgement. Cover Art by Artmosphere ERIA Research Project Report 2014, No.4 National Library of Indonesia Cataloguing in Publication Data ISBN: 978-602-8660-88-4 Contents Acknowledgement iv List of Tables vi List of Figures and Graphics viii Executive Summary x Chapter 1 Development Strategies and CADP 2.0 1 Chapter 2 Infrastructure for Connectivity and Innovation: The 7 Conceptual Framework Chapter 3 The Quality of Infrastructure and Infrastructure 31 Projects Chapter 4 The Assessment of Industrialisation and Urbanisation 41 Chapter 5 Assessment of Soft and Hard Infrastructure 67 Development Chapter 6 Three Tiers of Soft and Hard Infrastructure 83 Development Chapter 7 Quantitative Assessment on Hard/Soft Infrastructure 117 Development: The Geographical Simulation Analysis for CADP 2.0 Appendix 1 List of Prospective Projects 151 Appendix 2 Non-Tariff Barriers in IDE/ERIA-GSM 183 References 185 iii Acknowledgements The original version of the Comprehensive Asia Development Plan (CADP) presents a grand spatial design of economic infrastructure and industrial placement in ASEAN and East Asia. Since the submission of such first version of the CADP to the East Asia Summit in 2010, ASEAN and East Asia have made significant achievements in developing hard infrastructure, enhancing connectivity, and participating in international production networks. -
Mapping the Links Between ASEAN and the GMS, BIMP-EAGA, and IMT-GT
REGIONAL AND SUBREGIONAL PROGRAM LINKS Mapping the links between ASEAN and the GMS, BIMP-EAGA, and IMT-GT REGIONAL AND SUBREGIONAL PROGRAM LINKS Mapping the links between ASEAN and the GMS, BIMP-EAGA, and IMT-GT September 2013 © 2013 Asian Development Bank All rights reserved. Published 2013. Printed in the Philippines. ISBN 978-92-9254-202-3 (Print), 978-92-9254-203-0 (PDF) Publication Stock No. RPT135922-2 Cataloging-In-Publication Data Regional and Subregional Program Links: mapping the links between ASEAN and the GMS, BIMP-EAGA, and IMT-GT Mandaluyong City, Philippines: Asian Development Bank, 2013. 1. Regional cooperation and integration. 2. ASEAN. 3. GMS. 4. BIMP-EAGA. 5. IMT-GT. I. Asian Development Bank. The views expressed in this publication are those of the authors and do not necessarily reflect the views and policies of the Asian Development Bank (ADB) or its Board of Governors or the governments they represent. ADB does not guarantee the accuracy of the data included in this publication and accepts no responsibility for any consequence of their use. Use of the term “country” does not imply any judgment by the authors or ADB as to the legal or other status of any territorial entity. The symbol “$” represents the United States dollar unless otherwise indicated. “Asia” refers only to ADB’s Asian member economies. ADB encourages printing or copying information exclusively for personal and noncommercial use with proper acknowledgement of ADB. Users are restricted from reselling, redistributing, or creating derivative works for commercial purposes without the express, written consent of ADB. Photo credits (cover): ADB photo archive and Josephine Duque-Comia. -
1St IRF Asia Regional Congress & Exhibition
1st IRF Asia Regional Congress & Exhibition Bali, Indonesia November 17–19 , 2014 For Professionals. By Professionals. "Building the Trans-Asia Highway" Bali’s Mandara toll road Executive Summary International Road Federation Better Roads. Better World. 1 International Road Federation | Washington, D.C. ogether with the Ministry of Public Works Indonesia, we chose the theme “Building the Trans-Asia Highway” to bring new emphasis to a visionary project Tthat traces its roots back to 1959. This Congress brought the region’s stakeholders together to identify new and innovative resources to bridge the current financing gap, while also sharing case studies, best practices and new technologies that can all contribute to making the Trans-Asia Highway a reality. This Congress was a direct result of the IRF’s strategic vision to become the world’s leading industry knowledge platform to help countries everywhere progress towards safer, cleaner, more resilient and better connected transportation systems. The Congress was also a reflection of Indonesia’s rising global stature. Already the largest economy in Southeast Asia, Indonesia aims to be one of world’s leading economies, an achievement that will require the continued development of not just its own transportation network, but also that of its neighbors. Thank you for joining us in Bali for this landmark regional event. H.E. Eng. Abdullah A. Al-Mogbel IRF Chairman Minister of Transport, Kingdom of Saudi Arabia Indonesia Hosts the Region’s Premier Transportation Meeting Indonesia was the proud host to the 1st IRF Asia Regional Congress & Exhibition, a regional gathering of more than 700 transportation professionals from 52 countries — including Ministers, senior national and local government officials, academics, civil society organizations and industry leaders. -
Characterization and Transferability of Microsatellite Markers of the Cultivated Peanut (Arachis Hypogaea)
BMC Plant Biology BioMed Central Research article Open Access Characterization and transferability of microsatellite markers of the cultivated peanut (Arachis hypogaea) Marcos A Gimenes*1,2, Andrea A Hoshino1, Andrea VG Barbosa1, Dario A Palmieri1 and Catalina R Lopes1 Address: 1Laboratório de Biotecnologia e Genética Molecular (BIOGEM), Departamento de Genética, Instituto de Biociências, Universidade Estadual Paulista (UNESP), Botucatu, SP, Brazil and 2Instituto Agronômico de Campinas – RGV, Caixa Postal 28, Campinas, SP, Brazil Email: Marcos A Gimenes* - [email protected]; Andrea A Hoshino - [email protected]; Andrea VG Barbosa - [email protected]; Dario A Palmieri - [email protected]; Catalina R Lopes - [email protected] * Corresponding author Published: 27 February 2007 Received: 3 March 2006 Accepted: 27 February 2007 BMC Plant Biology 2007, 7:9 doi:10.1186/1471-2229-7-9 This article is available from: http://www.biomedcentral.com/1471-2229/7/9 © 2007 Gimenes et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The genus Arachis includes Arachis hypogaea (cultivated peanut) and wild species that are used in peanut breeding or as forage. Molecular markers have been employed in several studies of this genus, but microsatellite markers have only been used in few investigations. Microsatellites are very informative and are useful to assess genetic variability, analyze mating systems and in genetic mapping. The objectives of this study were to develop A. -
BELLA COOLA to FOUR MILE TRAIL
BELLA COOLA to FOUR MILE TRAIL Trail Location & Engineering Design Project sponsored by Bella Coola General Hospital Central Coast Regional District & Union of BC Municipalities December 14, 2009 PO Box 216, Hagensborg, BC V0T 1H0 Tel:250-982-2515, [email protected] BC-4Mile Trail Layout Report -i- TABLE OF CONTENTS 1 INTRODUCTION 1 1.1 Layout & Survey Method 1 1.2 Trail Design Criteria 1 2 TRAIL LAYOUT & DESCRIPTION 1 2.1 Cut and Fill 2 2.2 Partial Fill 2 2.3 Overland Fill 3 2.4 Flush Surfacing 3 2.5 Detailed Description 4 2.6 Tatsquan Creek Crossing Options 5 2.6.1 Option A - Hwy 20 Sidewalk 5 2.6.2 Option A2 – Widened Sidewalk on Hwy Bridge 5 2.6.3 Option B – Parallel Footbridge 6 2.6.4 Option C – Downstream Footbridge 7 3 ENVIRONMENT 8 3.1 Fish 8 3.2 Wildlife 8 4 FIELD REVIEW 9 5 CONSTRUCTION 9 5.1 Trail Components 11 5.1.1 Asphalt 11 5.1.2 Crush Gravel 11 5.1.3 Sub-grade Ballast 11 5.1.4 Foot Bridges 11 5.1.5 Culverts 11 5.1.6 Benches 12 5.1.7 Guards 12 5.1.8 Trail Posts 12 5.2 Next Engineering Steps 12 6 TRAIL MAINTENANCE 12 BC-4Mile Trail Layout Report -ii- APPENDIX A – AIRPHOTO MAP OF TRAIL 13 APPENDIX B – SURVEY MAP OF TRAIL 13 APPENDIX C – ENGINEERED PLAN, PROFILE & CROSS SECTIONS 13 Acknowledgement A number of individuals contributed time and knowledge to this initial stage of locating the proposed trail and Frontier Resource Management Ltd is very grateful for this help. -
Europe Price List
2019 Europe Price List EUROPE PRICE LIST 2019 Terms and Conditions of Sale Conditions générales de vente Condizioni generali di vendita Allgemeine Verkaufsbedingungen By placing an order, the customer Toutes les commandes passées Tutti gli ordini effettuati com- Mit Aufgabe einer Bestellung er- fully accepts the following Terms impliquent que l’acheteur accep- portano la piena accettazione, kennt der Kunde die folgenden and Conditions of Sale: te intégralement les Conditions da parte dell’acquirente, delle Allgemeinen Verkaufsbedingun- générales de vente suivantes : seguenti Condizioni Generali di gen in vollem Umfang an: 0. Validity Vendita: Price list valid from 18/02/2019. 0. Validité 0. Gültigkeit Tarif valable à partir de 18/02/2019. 0. Validità Die Preisliste gilt ab dem 1. Prices Listino valido dal 18/02/2019. 18/02/2019. The prices applied will be those 1. Prix valid on the date of reception of Les tarifs en vigueur s’appliquent 1. Prezzi 1. Preise the order (RRP, VAT not included). à la date de réception de la com- Verranno applicate le tariffe Es werden die Preise berechnet, All prices featured in the price list mande (prix PVPR, TVA non com- vigenti alla data di ricezione die am Tag des Auftrageingangs include the WEEE eco-fee. prise). Tous les prix indiqués dans dell’ordine (prezzi di vendita al gelten (UVP ohne Mehrwerts- la liste des tarifs comprennent pubblico consigliati, IVA esclusa). teuer). Alle angegebenen Preise 2. Delivery times l’éco-participation DEEE. Tutti i prezzi indicati nel listino sind einschließlich WEEE Gebühr. Delivery times will be confirmed at prezzi sono con contributo ECO- the moment of placing the order 2. -
Chapter A-10 Road Network Development Plan
Final Report The Study on the Road Network Development in the Kingdom of Cambodia October 2006 CHAPTER A-10 ROAD NETWORK DEVELOPMENT PLAN 10.1 Road Development Principle As identified in the existing road condition survey, road network system in Cambodia has sufficient coverage from the perspectives of road density and network, however, many of important roads are not functioning well mainly due to poor surface condition as well as narrow and poor temporary bridges with limited loading capacity. Based on the existing road condition stated above, the Study team establishes the following road development principle; (1) Improvement of Existing Road Network * Use existing road network as much as possible * Improvement of existing road network - Pavement up-grade for 1-Digit and 2-Digit roads - Maintenance for 3-Digit and rural roads (2) Strengthening of Road Network and Capacity * 4 lane widening, Ring Road and Bypass (3) Reinforcement of Road Network * Provision of alternative routes 10.2 Target of Road Network Development Based on the above road development principle as well as the 5 strategies developed in the previous chapter, the following target of road network development was established: Strategy 1: Multi Growth Pole Development Target: (1) Widening and upgrading of 1-Digit road (2) Construction of Bypass around major cities (3) Reinforcement of road network around Phnom Penh by Ring Road Strategy 2: National Integration Target: (1) Improvement of accessibility to provincial capital (2) Reinforcement of main 2-Digit roads Strategy -
ASEAN Connectivity, Project Information Sheet
ASEAN Connectivity Project Information Sheets one vision one identity one community The Association of Southeast Asian Nations (ASEAN) was established on 8 August 1967. The Member States of the Association are Brunei Darussalam, Cambodia, Indonesia, Lao PDR, Malaysia, Myanmar, Philippines, Singapore, Thailand and Viet Nam. The ASEAN Secretariat is based in Jakarta, Indonesia. The ASEAN Secretariat Public Outreach and Civil Society Division 70A Jalan Sisingamangaraja Jakarta 12110, Indonesia Phone : (62 21) 724-3372, 726-2991 Fax : (62 21) 739-8234, 724-3504 E-mail : [email protected] General information on ASEAN appears online at the ASEAN Website: www.asean.org Catalogue-in-Publication Data ASEAN Connectivity Jakarta: ASEAN Secretariat, August 2012 The text of this publication may be freely quoted or reprinted with proper acknowledgement. Copyright Association of Southeast Asian Nations (ASEAN) 2012 All rights reserved PHYSICAL CONNECTIVITY PrOjECT INfOrmATION SHEET mPAC PP/A1/01 CONSTRUCTION OF THE ASEAN HIGHWAY NETWORK (AHN) MISSING LINKS AND UPGRADE OF TRANSIT TRANSPORT ROUTES IN LAO PDR AND MYANMAR PrOjECT DESCrIPTION PrOjECT STATuS ASEAN HIGHWAY Given the growing regional integration and cooperation Seeking technical in ASEAN, the development of high quality transport assistance and funding NETWORK infrastructure is a crucial element to building a competitive ASEAN Community with equitable economic TArgET COmPLETION development. However, ASEAN with total land area DATE of around 4.4 million sq. km faces challenges with poor December 2015 quality of roads and incomplete road networks. The ASEAN Highway Network (AHN) project is a flagship ImPLEmENTINg bODIES infrastructure project that seeks to bring connectivity Ministry of Public across borders and confer many benefits, such as Works and Transport improved competitiveness of regional production of Lao PDR, Ministry networks, better trade and investment flows, and of Construction of reductions in development gaps. -
The Effect of Road Upgrading to Overland Trade in Asian Highway Network Ziyodullo PARPIEV ∗ Jamshid SODIKOV **
Eurasian Journal of Business and Economics 2008, 1 (2), 85-101. The Effect of Road Upgrading to Overland Trade in Asian Highway Network Ziyodullo PARPIEV ∗ Jamshid SODIKOV ** Abstract This paper investigates an impact of road upgrading and improvement on overland trade in 18 out of 32 Asian Highway Network member countries. A regression based cost model was developed. The results indicate that approximately 6.5 billion US dollars is required to upgrade and improve surface condition of the selected roads with total length of 15,842 km. The gravity model approach was adopted to quantitatively evaluate overland trade expansion assuming pessimistic and optimistic scenarios: improvements in road quality indices up to 50 and up to 75, respectively. The results suggests that in the first scenario total intra-regional trade will increase by about 20 percent or 48.7 billion US dollars annually, while second scenario predicts that trade will increase by about 35 percent or 89.5 billion US dollars annually. Keywords: Asian Highway Network, road transport, gravity model. Jel Classification: F12, F15, F17. ∗ Advisor-Economist, UNDP Uzbekistan Country Office, Email: [email protected] ** Chief Engineer, Road Research Institute, Tashkent, Uzbekistan The views expressed in this paper are those of the author(s) and do not necessarily represent those of organizations the authors are associated with. Ziyodullo PARPIEV & Jamshid SODIKOV 1. Introduction In 1992, the United Nations Economic and Social Commission for Asia and the Pacific (ESCAP) endorsed the Asian Land Transport Infrastructure Development (ALTID) project comprising of the Asian Highway and the Trans-Asian Railway network. The formalization of the Asian Highway, through the Intergovernmental Agreement on Asian Highway Network (AHN), was adopted in November 2003. -
Growing Together Articulates a Number of Proposals That Can Help the Region Exploit Its Huge Untapped Potential for Regional Economic Integration
i Photo by Warren Field ii FOREWORD For the global economy, these are difficult times. The world is emerging from a crisis whose aftershocks continue to resonate – trapping some of the richest economies in recession and shaking the foundations of one of the world’s major currencies. Here at ESCAP, there are historical echoes. What is now the Economic and Social Commission for Asia and the Pacific was founded more than 60 years ago – also in the aftermath of a global crisis. The countries of Asia and the Pacific established their new Commission partly to assist them in rebuilding their economies as they came out of the yoke of colonialism and the Second World War. The newly established ECAFE, as ESCAP was called then, held a ministerial conference on regional economic cooperation in 1963 that resolved to set up the Asian Development Bank with the aim of assisting the countries in the region in rebuilding their economies. Fifty years later, the Asia-Pacific region is again at a crossroads, on this occasion seeking ways and means to sustain its dynamism in a dramatically changed global context in the aftermath of a global financial and economic crisis. An important change is the fact that, burdened by huge debts and global imbalances, the advanced economies of the West are no longer able to play the role of engines of growth for the Asia-Pacific region that they played in the past. Hence, the Asia-Pacific region has to look for new engines of growth. The secretariat of ESCAP has argued over the past few years that regional developmental challenges, such as poverty and wide disparities in social and physical infrastructure, can be turned into opportunities for sustaining growth in the future.